Pub Date : 2023-04-01DOI: 10.4103/jras.jras_109_23
K. Sangeetha, Bhavana Prasher
{"title":"Ayurgenomics: A Novel Integrative Research Framework of Ayurveda and Genomics towards P5 Medicine","authors":"K. Sangeetha, Bhavana Prasher","doi":"10.4103/jras.jras_109_23","DOIUrl":"https://doi.org/10.4103/jras.jras_109_23","url":null,"abstract":"","PeriodicalId":394246,"journal":{"name":"Journal of Research in Ayurvedic Sciences","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116926325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BACKGROUND: In patients with hyperglycemia, the resistance to oral antihyperglycemic drugs may lead to insulin therapy. Insulin therapy has some limitations, such as the cost of medicine, dose monitoring, and the risk of hypoglycemia. The classical text of Ayurveda has described several formulations for treating diabetes. The role of Ayurveda antidiabetic formulations needs to be studied for controlling hyperglycemia and reducing the dose and frequency of insulin administration. Vijayasaradi capsule is an antidiabetic herbal formulation mainly utilized to treat hyperglycemia. Objective: This study aimed to evaluate the clinical efficacy of Vijayasaradi capsule as add-on management in the cases of insulin-dependent type 2 diabetes. MATERIALS AND METHODS: Seventy-nine patients of either sex with insulin-dependent diabetes mellitus (T2-IDDM) between 18 and 70 years were studied. The intervention for the control group (n = 38) was hypoglycemic drugs with insulin injections. The trial group (n = 41) was treated with the Vijayasaradi capsule, two capsules (500 mg each) thrice daily before food, hypoglycemic medicine, and insulin injection. The duration of the study was 3 months, and follow-ups were done weekly. Percentage changes of reduction in the units of insulin therapy, fasting and postprandial blood sugar levels, and hemoglobin A1c before and after the treatment and the associated subjective symptoms of type 2 diabetes were the primary outcome measures. RESULTS: The trial drug significantly decreased fasting blood sugar (P = 0.02) and postprandial blood sugar (P = 0.0001). The average insulin dose was also reduced from 33.27 ± 19 to 28.8 ± 80 units. A significant reduction (P = 0.001) in hemoglobin A1c was observed after the treatment. After the treatment, reduction in the maximum average insulin dose was also observed. CONCLUSION: Vijaysaradi capsule can be used as an add-on therapy to manage hyperglycemia and reduce insulin doses in patients with T2-IDDM.
{"title":"Efficacy of Vijayasaradi capsule as add-on management in insulin-dependent type 2 diabetes – A randomized standard controlled clinical trial","authors":"Nidhi Verma, M. Goyal, Jitendra Varsakiya","doi":"10.4103/jras.jras_79_22","DOIUrl":"https://doi.org/10.4103/jras.jras_79_22","url":null,"abstract":"BACKGROUND: In patients with hyperglycemia, the resistance to oral antihyperglycemic drugs may lead to insulin therapy. Insulin therapy has some limitations, such as the cost of medicine, dose monitoring, and the risk of hypoglycemia. The classical text of Ayurveda has described several formulations for treating diabetes. The role of Ayurveda antidiabetic formulations needs to be studied for controlling hyperglycemia and reducing the dose and frequency of insulin administration. Vijayasaradi capsule is an antidiabetic herbal formulation mainly utilized to treat hyperglycemia. Objective: This study aimed to evaluate the clinical efficacy of Vijayasaradi capsule as add-on management in the cases of insulin-dependent type 2 diabetes. MATERIALS AND METHODS: Seventy-nine patients of either sex with insulin-dependent diabetes mellitus (T2-IDDM) between 18 and 70 years were studied. The intervention for the control group (n = 38) was hypoglycemic drugs with insulin injections. The trial group (n = 41) was treated with the Vijayasaradi capsule, two capsules (500 mg each) thrice daily before food, hypoglycemic medicine, and insulin injection. The duration of the study was 3 months, and follow-ups were done weekly. Percentage changes of reduction in the units of insulin therapy, fasting and postprandial blood sugar levels, and hemoglobin A1c before and after the treatment and the associated subjective symptoms of type 2 diabetes were the primary outcome measures. RESULTS: The trial drug significantly decreased fasting blood sugar (P = 0.02) and postprandial blood sugar (P = 0.0001). The average insulin dose was also reduced from 33.27 ± 19 to 28.8 ± 80 units. A significant reduction (P = 0.001) in hemoglobin A1c was observed after the treatment. After the treatment, reduction in the maximum average insulin dose was also observed. CONCLUSION: Vijaysaradi capsule can be used as an add-on therapy to manage hyperglycemia and reduce insulin doses in patients with T2-IDDM.","PeriodicalId":394246,"journal":{"name":"Journal of Research in Ayurvedic Sciences","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127277513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.4103/jras.jras_103_23
Tripta Dixit
{"title":"India’s exceptional plant-oriented translational sector – An ayush exports case report","authors":"Tripta Dixit","doi":"10.4103/jras.jras_103_23","DOIUrl":"https://doi.org/10.4103/jras.jras_103_23","url":null,"abstract":"","PeriodicalId":394246,"journal":{"name":"Journal of Research in Ayurvedic Sciences","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125645270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Publication of research work is one of the most crucial parts of knowledge transfer. Currently, scientific articles are the most popular and effective mode of knowledge dissemination. Publishing in peer-reviewed journals maintains the integrity of scientific information and filters the data based on irrational and poor-quality evidence. It establishes the significance and originality of the study and provides an authentic form of scientific knowledge. There are sufficient numbers of peer-reviewed journals that publish research studies conducted on traditional medicines, but searching for and selecting a journal is a brainstorming and time-consuming task. Hence, scholars and researchers face difficulty selecting one to publish their scientific work. Therefore, the present article has been drafted to provide a convenient and pragmatic reference platform that may help scholars to search and select relevant and credible journals to publish their research works. A search has been conducted to gather information using search terms such as “Ayu,” “Ayurveda,” and “Ethnomedicine” on the University Grants Commission-Consortium for Academic and Research Ethics (UGC-CARE) Group-I (journals found qualified through UGC-CARE protocols, 317 journals) and Group-II (journals indexed in globally recognized databases, 2415 journals) lists. After screening a total of 2732 journals, 61 peer-reviewed journals have been identified where research studies related to traditional/conventional medicine can be communicated as per the suitability and scope of journals. Present article proffers information to identify good scientific journals’ significance of publishing in credible journals with a reference list of peer-reviewed quality journals to researchers and scholars of the traditional system of medicine.
{"title":"Credible journals for publication of research in traditional system of medicine: A bird’s eye view","authors":"Rohit Singh, Pramod Yadav, Pradeep Prajapati","doi":"10.4103/jras.jras_92_22","DOIUrl":"https://doi.org/10.4103/jras.jras_92_22","url":null,"abstract":"Publication of research work is one of the most crucial parts of knowledge transfer. Currently, scientific articles are the most popular and effective mode of knowledge dissemination. Publishing in peer-reviewed journals maintains the integrity of scientific information and filters the data based on irrational and poor-quality evidence. It establishes the significance and originality of the study and provides an authentic form of scientific knowledge. There are sufficient numbers of peer-reviewed journals that publish research studies conducted on traditional medicines, but searching for and selecting a journal is a brainstorming and time-consuming task. Hence, scholars and researchers face difficulty selecting one to publish their scientific work. Therefore, the present article has been drafted to provide a convenient and pragmatic reference platform that may help scholars to search and select relevant and credible journals to publish their research works. A search has been conducted to gather information using search terms such as “Ayu,” “Ayurveda,” and “Ethnomedicine” on the University Grants Commission-Consortium for Academic and Research Ethics (UGC-CARE) Group-I (journals found qualified through UGC-CARE protocols, 317 journals) and Group-II (journals indexed in globally recognized databases, 2415 journals) lists. After screening a total of 2732 journals, 61 peer-reviewed journals have been identified where research studies related to traditional/conventional medicine can be communicated as per the suitability and scope of journals. Present article proffers information to identify good scientific journals’ significance of publishing in credible journals with a reference list of peer-reviewed quality journals to researchers and scholars of the traditional system of medicine.","PeriodicalId":394246,"journal":{"name":"Journal of Research in Ayurvedic Sciences","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114536322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Educational reforms introduced by NCISM in lines with Mann Ki Baat promulgations","authors":"BS Prasad, J. Deopujari","doi":"10.4103/jras.jras_74_23","DOIUrl":"https://doi.org/10.4103/jras.jras_74_23","url":null,"abstract":"","PeriodicalId":394246,"journal":{"name":"Journal of Research in Ayurvedic Sciences","volume":"3 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132836961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
INTRODUCTION: Vitiligo is one of the major skin diseases affecting the normal pigmentation of the skin. It is an auto-immune disorder resulting in skin hypopigmentation due to reduced melanin production. In Ayurveda classical texts, the external application of Shwitrahara Lepa (SHL) and Avalgujabeejadi Lepa (AGL) is indicated for managing vitiligo. Hence, given literary indication, the present study was undertaken to evaluate the efficacy of SHL and AGL in managing vitiligo. MATERIALS AND METHODS: An open-label, parallel-group, randomized, controlled clinical study was conducted among 40 participants aged between 21 and 60 diagnosed with vitiligo. The participants were randomly assigned into two equal groups. Group A was treated by using an external application of SHL with water. Group B received AGL external application with cow urine. The external application of the interventions was done over the lesion once a day following early morning (7:00 a.m.) sunlight exposure for 15 min daily for 45 days. The effect of therapy was assessed through clinical parameters such as Vitiligo Area Scoring Index (VASI), pigmentation, margin, and the number of lesions along with classical symptoms of vitiligo, such as discoloration of the skin, reddish or coppery discoloration, skin dryness, burning sensation, itching, and thickening of the skin. RESULTS: The results of the study indicate that both SHL and AGL are significant in improving the score of VASI (P < 0.001) and pigmentation and reducing the margin of the lesions compared to baseline. Significant reduction in skin dryness and itching was noted in both SHL (P = 0.004, P = 0.023) and AGL (P = 0.034, P = 0.009) groups. SHL also significantly reduced whitish skin discoloration and burning sensation (P < 0.05). On comparing the effect of SHL and AGL, statistically nonsignificant results (P > 0.05) were obtained for all the assessment parameters, indicating that both interventions are equally effective. No adverse drug reactions were noted. CONCLUSION: Both the formulations are equally effective.
{"title":"Comparative efficacy of ayurveda interventions Shwitrahara Lepa and Avalgujabeejadi Lepa in the Management of Shwitra (Vitiligo): An open-labeled, parallel-group, randomized, controlled clinical study","authors":"Bhumika Saxena, UP Sowmyashree, G. Gopala Krishna","doi":"10.4103/jras.jras_71_22","DOIUrl":"https://doi.org/10.4103/jras.jras_71_22","url":null,"abstract":"INTRODUCTION: Vitiligo is one of the major skin diseases affecting the normal pigmentation of the skin. It is an auto-immune disorder resulting in skin hypopigmentation due to reduced melanin production. In Ayurveda classical texts, the external application of Shwitrahara Lepa (SHL) and Avalgujabeejadi Lepa (AGL) is indicated for managing vitiligo. Hence, given literary indication, the present study was undertaken to evaluate the efficacy of SHL and AGL in managing vitiligo. MATERIALS AND METHODS: An open-label, parallel-group, randomized, controlled clinical study was conducted among 40 participants aged between 21 and 60 diagnosed with vitiligo. The participants were randomly assigned into two equal groups. Group A was treated by using an external application of SHL with water. Group B received AGL external application with cow urine. The external application of the interventions was done over the lesion once a day following early morning (7:00 a.m.) sunlight exposure for 15 min daily for 45 days. The effect of therapy was assessed through clinical parameters such as Vitiligo Area Scoring Index (VASI), pigmentation, margin, and the number of lesions along with classical symptoms of vitiligo, such as discoloration of the skin, reddish or coppery discoloration, skin dryness, burning sensation, itching, and thickening of the skin. RESULTS: The results of the study indicate that both SHL and AGL are significant in improving the score of VASI (P < 0.001) and pigmentation and reducing the margin of the lesions compared to baseline. Significant reduction in skin dryness and itching was noted in both SHL (P = 0.004, P = 0.023) and AGL (P = 0.034, P = 0.009) groups. SHL also significantly reduced whitish skin discoloration and burning sensation (P < 0.05). On comparing the effect of SHL and AGL, statistically nonsignificant results (P > 0.05) were obtained for all the assessment parameters, indicating that both interventions are equally effective. No adverse drug reactions were noted. CONCLUSION: Both the formulations are equally effective.","PeriodicalId":394246,"journal":{"name":"Journal of Research in Ayurvedic Sciences","volume":"189 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133564300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.4103/jras.jras_108_23
D. Londhe, M. Gundeti
{"title":"Perspective on- ‘Millet for Health’ initiatives by Ayush Institutes across India based on the Hon’ble Prime Minister’s Millet-promotion call through Mann ki Baat","authors":"D. Londhe, M. Gundeti","doi":"10.4103/jras.jras_108_23","DOIUrl":"https://doi.org/10.4103/jras.jras_108_23","url":null,"abstract":"","PeriodicalId":394246,"journal":{"name":"Journal of Research in Ayurvedic Sciences","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132470507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.4103/jras.jras_104_23
G. Krishnan
{"title":"WHO Global Centre for Traditional Medicinev","authors":"G. Krishnan","doi":"10.4103/jras.jras_104_23","DOIUrl":"https://doi.org/10.4103/jras.jras_104_23","url":null,"abstract":"","PeriodicalId":394246,"journal":{"name":"Journal of Research in Ayurvedic Sciences","volume":"187 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114215001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Emphasizing evidence-based research: a way forward to robust validity of clinical research in Ayurveda","authors":"Rabina Acharya","doi":"10.4103/jras.jras_49_23","DOIUrl":"https://doi.org/10.4103/jras.jras_49_23","url":null,"abstract":"","PeriodicalId":394246,"journal":{"name":"Journal of Research in Ayurvedic Sciences","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121570960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ancient Indian medicine offerings to the greying modern world: Stenting the stumble blocks","authors":"S. Chaturvedi, Vinod Diwan","doi":"10.4103/jras.jras_81_23","DOIUrl":"https://doi.org/10.4103/jras.jras_81_23","url":null,"abstract":"","PeriodicalId":394246,"journal":{"name":"Journal of Research in Ayurvedic Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115700916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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