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Ocular manifestations in post-coronavirus disease-2019 patients in a tertiary care institute in North-East India: A cross-sectional study 印度东北部一家三级医疗机构2019年冠状病毒病后患者的眼部表现:一项横断面研究
Q4 Medicine Pub Date : 2022-09-01 DOI: 10.4103/jms.jms_75_22
Bigyabati Rajkumari, Victor Rajkumar, D. Chingakham, R. Bishwalata
Background: There are various studies on coronavirus disease-2019 (COVID-19) from globally which are mainly focused on respiratory and other medical manifestations of the disease. There are few studies on ocular manifestations in COVID-19 and post-COVID-19 patients. Objectives: We aim to investigate the ocular manifestations of hospitalized post-COVID-19 patients at a tertiary care institute in the North Eastern part of India. Materials and Methods: This cross-sectional study was conducted among hospitalized post-COVID-19 patients 18 years and above during July 1, 2021–December 31, 2021. A universal sampling method was employed. A structured pro forma was used for data collection along with detailed ocular examination. Descriptive statistics were generated from collected data. Approval of the study was obtained from the institutional ethics committee. Results: A total of 105 patients were included in the study with ages ranging from 18 to 85 years and males constituting 63.8%. Around two-thirds of the patients (70, 66.7%) had not received any vaccination. Chest X-ray showed bilateral moderate consolidation in 59 (56.2%) patients. Twelve (11.4%) patients developed ocular signs and symptoms. Dry eye, redness of the eye, dimness of vision, itching, blurring of vision, and discharge from the eyes are some of the symptoms encountered. Two patients developed subconjunctival hemorrhage, one patient had a retinal hemorrhage and exposure keratopathy was detected in one patient. Conclusion: In this study, 11.4% of hospitalized post-COVID-19 patients have ocular manifestations. Post-COVID-19 syndrome could affect the eyes thus necessitating meticulous follow-up of patients who recovered from COVID-19.
背景:全球有各种关于2019冠状病毒病(新冠肺炎)的研究,主要集中在该疾病的呼吸道和其他医学表现上。关于新冠肺炎和新冠肺炎后患者眼部表现的研究很少。目的:我们旨在调查印度东北部一家三级医疗机构住院的COVID-19后患者的眼部表现。材料和方法:这项横断面研究于2021年7月1日至2021年12月31日在18岁及以上住院的COVID-19后患者中进行。采用了通用抽样方法。结构化的形式用于数据收集以及详细的眼部检查。描述性统计数据是根据收集的数据生成的。该研究获得了机构伦理委员会的批准。结果:共有105名患者被纳入研究,年龄在18至85岁之间,男性占63.8%。约三分之二的患者(70,66.7%)没有接种任何疫苗。胸部X线片显示59例(56.2%)患者双侧中度实变。12名(11.4%)患者出现眼部体征和症状。眼睛干燥、发红、视力模糊、瘙痒、视力模糊和眼睛分泌物都是会出现的一些症状。两名患者出现结膜下出血,一名患者出现视网膜出血,其中一名患者发现暴露性角膜病变。结论:在本研究中,11.4%的COVID-19后住院患者有眼部表现。COVID-19后综合征可能会影响眼睛,因此需要对COVID-19]康复患者进行细致的随访。
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引用次数: 0
A comparison of intravenous paracetamol and intravenous paracetamol with dexmedetomidine for postoperative analgesia management in gynecological surgeries – A prospective randomized double-blinded study 对乙酰氨基酚静脉注射与右美托咪定在妇科手术术后镇痛管理中的比较——一项前瞻性随机双盲研究
Q4 Medicine Pub Date : 2022-09-01 DOI: 10.4103/jms.jms_23_22
A. Srinithi, T. Prasad, Rajarajeswaran Krishnan, S. Kumar
Background: Substitution of nonopioid analgesic drugs in place of opioids perioperatively has become mandatory recently due to the development of the opioid crisis. This study emphasizes nonopioid alternatives to significantly reduce perioperative opioid consumption in gynecological surgeries. Objective: This study compared the efficacy of intravenous paracetamol and intravenous (iv) paracetamol with dexmedetomidine in terms of postoperative visual analog scale (VAS) score, sedation score, hemodynamic changes, and analgesic requirement in gynecological procedures. Materials and Methods: This prospective randomized double-blinded study included females between the age of 18 and 60 years who underwent gynecological surgeries. Group P received iv paracetamol 1 g infusion, Group DP received an infusion of iv paracetamol 1 g with dexmedetomidine at a dose of 0.5 μg/kg as infusion 10 min before the end of the surgery over 10 min. VAS score, sedation score, hemodynamic changes, and rescue analgesic requirement were observed up to 12 h postoperatively. Results: Group DP had a significantly lower VAS score in the 4th and 6th h (P = 0.009 and 0.023, respectively). Group P had significantly higher rescue analgesia than Group DP (P = 0.005). Group DP had a significantly higher heart rate than Group P at the 2nd and 4th h (P = 0.001) postoperatively. Group DP had significantly lower mean arterial pressure than Group P at 2 h (P = 0.001). Sedation score among Group DP was significantly higher till 10 h. Conclusion: Combining iv dexmedetomidine and paracetamol effectively reduces postoperative pain, analgesic requirements with good sedation score, and mild hemodynamic changes. Hence, it effectively increases postoperative comfort and reduces hospital stay and cost.
背景:由于阿片类药物危机的发展,非阿片类镇痛药物替代阿片类药物在围手术期已成为强制性的。本研究强调非阿片类药物的替代品可以显著减少妇科手术围手术期阿片类药物的消耗。目的:比较静脉注射扑热息痛和静脉注射(iv)扑热息痛与右美托咪定在妇科手术中术后视觉模拟评分(VAS)评分、镇静评分、血流动力学变化和镇痛需求的疗效。材料和方法:本前瞻性随机双盲研究纳入了年龄在18岁至60岁之间接受妇科手术的女性。P组患者术后10 min静脉滴注扑热息痛1 g, DP组患者术后10 min内静脉滴注右美托咪定注射液1 g,剂量为0.5 μg/kg。观察术后12 h VAS评分、镇静评分、血流动力学变化及救援镇痛需求。结果:DP组VAS评分在第4、6 h明显低于对照组(P = 0.009、0.023)。P组抢救镇痛明显高于DP组(P = 0.005)。DP组术后2 h、4 h心率明显高于P组(P = 0.001)。DP组2 h平均动脉压明显低于P组(P = 0.001)。结论:右美托咪定联合扑热息痛可有效减轻术后疼痛,镇痛需求,镇静评分良好,血流动力学改变轻微。因此,它有效地提高了术后舒适度,减少了住院时间和费用。
{"title":"A comparison of intravenous paracetamol and intravenous paracetamol with dexmedetomidine for postoperative analgesia management in gynecological surgeries – A prospective randomized double-blinded study","authors":"A. Srinithi, T. Prasad, Rajarajeswaran Krishnan, S. Kumar","doi":"10.4103/jms.jms_23_22","DOIUrl":"https://doi.org/10.4103/jms.jms_23_22","url":null,"abstract":"Background: Substitution of nonopioid analgesic drugs in place of opioids perioperatively has become mandatory recently due to the development of the opioid crisis. This study emphasizes nonopioid alternatives to significantly reduce perioperative opioid consumption in gynecological surgeries. Objective: This study compared the efficacy of intravenous paracetamol and intravenous (iv) paracetamol with dexmedetomidine in terms of postoperative visual analog scale (VAS) score, sedation score, hemodynamic changes, and analgesic requirement in gynecological procedures. Materials and Methods: This prospective randomized double-blinded study included females between the age of 18 and 60 years who underwent gynecological surgeries. Group P received iv paracetamol 1 g infusion, Group DP received an infusion of iv paracetamol 1 g with dexmedetomidine at a dose of 0.5 μg/kg as infusion 10 min before the end of the surgery over 10 min. VAS score, sedation score, hemodynamic changes, and rescue analgesic requirement were observed up to 12 h postoperatively. Results: Group DP had a significantly lower VAS score in the 4th and 6th h (P = 0.009 and 0.023, respectively). Group P had significantly higher rescue analgesia than Group DP (P = 0.005). Group DP had a significantly higher heart rate than Group P at the 2nd and 4th h (P = 0.001) postoperatively. Group DP had significantly lower mean arterial pressure than Group P at 2 h (P = 0.001). Sedation score among Group DP was significantly higher till 10 h. Conclusion: Combining iv dexmedetomidine and paracetamol effectively reduces postoperative pain, analgesic requirements with good sedation score, and mild hemodynamic changes. Hence, it effectively increases postoperative comfort and reduces hospital stay and cost.","PeriodicalId":39636,"journal":{"name":"JMS - Journal of Medical Society","volume":"36 1","pages":"118 - 123"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46846434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Infodemic and its unwanted effect on COVID-19 信息传播及其对新冠肺炎的不良影响
Q4 Medicine Pub Date : 2022-09-01 DOI: 10.4103/jms.jms_59_21
P. Sookaromdee, V. Wiwanitkit
COVID-19 is a new disease that results in a worldwide pandemic. A rapid increasing of studies regarding occurs within a few period after its first emergence. The infodemic of COVID-19 data occurs. On the one hand, it can bring useful new knowledge. On the other hand, the negative impact such as misconduct and exaggeration off data occurs. In addition, since this new disease occurs in the IT era, the public health communication through social media regarding COVID-19 is also an interesting public health phenomenon. In this brief report, the authors summarize and discuss on infodemic and its unwanted effect on COVID-19.
COVID-19是一种导致全球大流行的新疾病。在其首次出现后的几段时间内,对其的研究迅速增加。COVID-19数据大爆发。一方面,它能带来有用的新知识。另一方面,也会产生不当行为、数据夸大等负面影响。此外,由于这种新疾病发生在IT时代,通过社交媒体进行关于COVID-19的公共卫生传播也是一个有趣的公共卫生现象。在这篇简短的报告中,作者总结和讨论了信息疫情及其对COVID-19的不良影响。
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引用次数: 0
SARS-CoV-2 and Helicobacter pylori and some hematological parameters: A case–control study 严重急性呼吸系统综合征冠状病毒2型和幽门螺杆菌及一些血液学参数:一项病例对照研究
Q4 Medicine Pub Date : 2022-09-01 DOI: 10.4103/jms.jms_55_22
F. AL-Khikani, Ahmed Al-Hussainy, Alia A. Hussein, Rasha Alshamary
Background: The SARS-CoV-2 associated with bacterial infection represents a serious public health challenge. Recently, there is a remarkable increase in the number of researches that confirms the effect of Helicobacter pylori on pulmonary diseases. Aim: The goal of this research was to see how H. pylori affected the presentation of COVID-19 infections as a prospective risk factor. Materials and Methods: This research was conducted in Babylon, Iraq, from January 1, 2022, to March 5, 2022. A total of 180 people were engaged in this study, with 90 patients identified with SARS-CoV-2 by polymerase chain reaction testing and 90 people serving as a control group. Antibody screening assays on blood samples were used to look for antibodies against H. pylori. The samples were processed for complete blood count and ABO blood group. Results: COVID-19 infection was more frequent in females than in males, especially between 31 and 45 years. When compared to healthy people, COVID-19 patients had a higher white blood cell count (P = 0.0001) and a lower lymphocyte count (P = 0.0001). H. pylori and COVID-19 have been found to have a strong relationship, especially in females. When comparing patients to healthy people, blood group A is the most common. Conclusion: People with H. pylori infections are considerably more sensitive to COVID-19 than people without H. pylori infections (P = 0.011). In combination with SARS-CoV-2, IgG for H. pylori might be a risk factor.
背景:与细菌感染相关的严重急性呼吸系统综合征冠状病毒2型是一个严重的公共卫生挑战。最近,证实幽门螺杆菌对肺部疾病影响的研究数量显著增加。目的:本研究的目的是了解幽门螺杆菌如何影响新冠肺炎感染的表现,将其作为一个前瞻性风险因素。材料和方法:本研究于2022年1月1日至2022年3月5日在伊拉克巴比伦进行。共有180人参与了这项研究,其中90名患者通过聚合酶链式反应检测被确认为严重急性呼吸系统综合征冠状病毒2型,90人作为对照组。使用血液样本的抗体筛选试验来寻找针对幽门螺杆菌的抗体。对样本进行了全血细胞计数和ABO血型分析。结果:新冠肺炎感染女性比男性更常见,尤其是在31至45岁之间。与健康人相比,新冠肺炎患者的白细胞计数较高(P=0.0001),淋巴细胞计数较低(P=0.0001。当将患者与健康人进行比较时,A血型是最常见的。结论:幽门螺杆菌感染者对新冠肺炎的敏感性明显高于未感染幽门螺杆菌的人(P=0.011)。与SARS-CoV-2相结合,幽门螺杆菌IgG可能是一个危险因素。
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引用次数: 3
Assessment of depression and suicidal risk in patients with psoriasis: A hospital-based cross sectional study 银屑病患者抑郁和自杀风险的评估:一项基于医院的横断面研究
Q4 Medicine Pub Date : 2022-09-01 DOI: 10.4103/jms.jms_88_20
Pranjal Dey, R. Zaman, J. Nath
Background: Psoriasis is one of the common psychosomatic illnesses which have impairment of physical, psychological, social functioning of an individual. This impairment may lead to psychiatric morbidities such as anxiety disorders and depressive disorder which increase the suicidal risk in these patients. The present hospital-based comparative study was carried out to evaluate the depression and suicidal risk in patients with psoriasis and to compare them with healthy control. Methods: This was a hospital-based cross-sectional study. Fifty patients with psoriasis were enrolled for the study after their informed consent with purposive sampling method from the department of dermatology in a tertiary care hospital in the northeastern part of India and compared them with those of the control group. The severity of psoriasis was assessed using the Psoriasis Area and Severity Index scale. The same patients were evaluated by the International Classification of Mental and Behavioral Disorders tenth revision research criteria along with the Hamilton Rating Scale for Depression and suicidal risk assessment form to diagnose and grade depression and assess for suicidal risk. Data were analyzed in SPSS version 16.0. Results: The incidence of depression was significantly higher in the psoriasis patient group (44%) in comparison to the control group. Among them, 50% of the depressed patients had mild depression and 31.9% of the patients had very severe depression with death wish with suicidal ideation. Furthermore, 4.6% of the depressed patients have a high risk of suicide. Conclusions: These findings indicate the need of early recognition of depression and suicidal risk among these patients and their early intervention will improve the primary disease process and will prevent a devastating outcome like suicide.
背景:银屑病是一种常见的心身疾病,会损害个体的身体、心理和社会功能。这种损伤可能导致焦虑症和抑郁障碍等精神疾病,从而增加这些患者的自杀风险。本项基于医院的比较研究旨在评估银屑病患者的抑郁和自杀风险,并将其与健康对照组进行比较。方法:这是一项基于医院的横断面研究。50名银屑病患者在知情同意后,从印度东北部一家三级护理医院的皮肤科采用有目的的抽样方法参与了这项研究,并将他们与对照组的患者进行了比较。使用银屑病面积和严重程度指数量表评估银屑病的严重程度。同样的患者通过国际精神和行为障碍分类第十次修订研究标准以及汉密尔顿抑郁评定量表和自杀风险评估表进行评估,以诊断和分级抑郁并评估自杀风险。数据采用SPSS 16.0版软件进行分析。结果:银屑病患者组的抑郁症发生率(44%)明显高于对照组。其中,50%的抑郁症患者有轻度抑郁症,31.9%的患者有非常严重的抑郁症,并有自杀念头。此外,4.6%的抑郁症患者有较高的自杀风险。结论:这些发现表明,需要尽早认识到这些患者的抑郁和自杀风险,他们的早期干预将改善原发性疾病的进程,并防止自杀等毁灭性后果。
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引用次数: 0
A comparative study on sequential single-agent chemotherapy followed by radiation versus single-agent chemotherapy alone in elderly patients of metastatic non-small cell lung cancer 顺序单药化疗加放疗与单药化疗治疗老年转移性非小细胞肺癌的比较研究
Q4 Medicine Pub Date : 2022-09-01 DOI: 10.4103/jms.jms_69_22
A. Devi, Laishram Devi, Y. Singh, Thangjam Nirpendra, Ramthaipou Kamei, M. Ramalingam
Background: Stage IV non-small cell lung cancer (NSCLC) in elderly patients typically has a poor prognosis and addition of aggressive local therapy to the systemic therapy could provide encouraging outcomes with prolonged survival in certain patients with stage IV NSCLC. Objectives: The aim of this study is to compare the treatment response and progression-free survival (PFS) between single-agent chemotherapy (CT) followed by external-beam radiotherapy versus single-agent CT alone in elderly patients with metastatic NSCLC. Materials and Methods: In a randomized prospective study, after taking Ethical committees approval, 40 patients aged from 60 to 82 years were enrolled and divided into two equal groups: Arm A and Arm B. Both the arms received Gemcitabine 1 g/m2/dose as 30 min intravenous infusion on D1, D8, and D15 of 28-day cycle or D1 and D8 of a 21-day cycle for a total of 3–4 cycles, whereas Arm A received radiation 45–55 Gy @ 180 cgy/fraction after CT. Treatment response and PFS against time were analyzed using Friedman's test and Kaplan − Meier method. P < 0.05 was considered statistically significant. Results: The demographic profiles of the patients were comparable between the two groups. Most patients have Stage IV M1b disease and squamous cell carcinoma subtype and bone metastasis. There were marked symptomatic improvements in both the arms. The overall treatment response was 70.0% in Arm A and 50.0% in Arm B with median follow-up was 8 months. Median PFS and overall survival were 5 months and 8 months for arm A, respectively whereas it was 4 months and 7 months for Arm B (P = 0.03). Conclusion: In this study, it was found that sequential single agent CT followed by radiation has shown survival advantage in certain patients with Stage IV NSCLC.
背景:老年患者IV期非小细胞肺癌(NSCLC)通常预后较差,在全身治疗的基础上增加积极的局部治疗可以提供令人鼓舞的结果,延长某些IV期NSCLC患者的生存期。目的:本研究的目的是比较老年转移性NSCLC患者单药化疗(CT)加外束放疗与单药CT治疗的治疗反应和无进展生存期(PFS)。材料与方法:在一项随机前瞻性研究中,经伦理委员会批准,入组40例年龄在60 ~ 82岁的患者,分为两组:a组和b组。两组均接受吉西他滨1 g/m2/剂量30 min静脉输注,D1、D8、D15为28天周期或D1、D8为21天周期,共3-4个周期,而a组在CT后接受45-55 Gy @ 180 cgy/分次的放疗。采用Friedman's检验和Kaplan - Meier方法分析治疗反应和PFS随时间的变化。P < 0.05为差异有统计学意义。结果:两组患者的人口学特征具有可比性。大多数患者有IV期M1b疾病和鳞状细胞癌亚型和骨转移。两只手臂的症状都有明显改善。A组总体治疗有效率为70.0%,B组为50.0%,中位随访时间为8个月。A组的中位PFS和总生存期分别为5个月和8个月,而B组为4个月和7个月(P = 0.03)。结论:本研究发现,在某些IV期NSCLC患者中,序贯单药CT加放疗显示出生存优势。
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引用次数: 0
Epidemiological survey of fatal road traffic accident in Imphal, Manipur 曼尼普尔邦英帕尔致命道路交通事故的流行病学调查
Q4 Medicine Pub Date : 2022-05-01 DOI: 10.4103/jms.jms_43_22
Pabitramala Nandeibam, K. Pradipkumar, Supriya Keisham, H. Nabachandra
Background: Approximately 1.3 million people die each year as a result of road traffic accidents (RTAs). According to the National Crime Record Bureau, a total of 368,828 traffic accidents were reported in the country in 2020, and out of these, 96% of the cases were due to RTAs with 354,796 cases and 37% fatality. Objectives: The objective is to study the demographic profile of victims of fatal road accidents. Materials and Methods: A cross-sectional study was carried out in the department of forensic medicine of a tertiary care teaching hospital in Imphal on all cases of fatal RTA brought in between October 2015 and September 2018. All data including the postmortem findings were analyzed and presented. Results: Out of 478 medicolegal autopsies conducted during the study period, 159 (33.3%) were vehicular accident fatalities. The majority of the victims were males in the age group of >20–30 years (22.64%) and pedestrians (30.82%). Most of the accidents (40.88%) occurred during the afternoon period between 12 Noon and 6 PM and in the winter months (50.9%), with maximum cases occurring on national highways (55.3%). The cause of death of the victims was due to head injuries in 42.14%. Conclusions: Several factors are responsible for RTAs. There is clearly a need for road safety education among road users. The licensing authorities should adopt stricter, more comprehensive, and scientifically based test.
背景:每年约有130万人死于道路交通事故。根据国家犯罪记录局的数据,2020年,该国共报告了368828起交通事故,其中96%的案件是由RTA造成的,354796起,37%的死亡。目的:目的是研究致命道路事故受害者的人口概况。材料和方法:在英帕尔一家三级护理教学医院的法医科对2015年10月至2018年9月期间发生的所有致命RTA病例进行了横断面研究。对包括尸检结果在内的所有数据进行了分析和呈现。结果:在研究期间进行的478例法医尸检中,159例(33.3%)为交通事故死亡。大多数受害者是年龄在20-30岁以上的男性(22.64%)和行人(30.82%)。大多数事故(40.88%)发生在中午12点到下午6点之间的下午时段和冬季月份(50.9%),其中发生在国道上的病例最多(55.3%)。受害者的死因是头部受伤,占42.14%。结论:RTAs有几个因素。道路使用者显然需要进行道路安全教育。发证机关应采取更严格、更全面、更科学的检测方法。
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引用次数: 0
Effect of COVID-19 on sleep pattern, mobile usage, and serum melatonin level among 1st-year medical students 新冠肺炎对医学生睡眠模式、手机使用和血清褪黑素水平的影响
Q4 Medicine Pub Date : 2022-05-01 DOI: 10.4103/jms.jms_150_21
Lalmalsawma Hnamte, Jayshree Phurailatpam, Memeeka Laishram
Background: The COVID-19 pandemic has enforced a new norm in the world with maximum dependence on technology in day-to-day living as well as the academic atmosphere. Globally, students are profoundly affected but more specifically medical students are subjected to immense stress, which is bound to affect their sleep and thus the sleep-regulating hormone, melatonin. Young medical students right at the entry to their professional career have, therefore, been hit by the changing scenario with most classes becoming online and increasing dependence on technological gadgets such as smartphones and laptops. Aims and Objectives: The purpose of the study was to determine the sleep pattern of 1st-year medical students, survey their mobile phone use, and to estimate their serum melatonin levels during the COVID-19 pandemic. Materials and Methods: This cross-sectional study was done in a Northeast India Medical Institute using standard questionnaires, Pittsburgh's Sleep Quality Index (PSQI) and Problematic Mobile Phone Usage Questionnaire among medical students and estimating their early morning serum melatonin level by ELISA assay. Statistical Analysis: Data collected were entered in SSPS version 21 and analyzed using descriptive measures, and statistical significances were set at P < 0.05. Results: One hundred and one students (Male: 49 and Female: 52) in the age range of 18–23 years responded to the study which recorded poor sleep quality in 53.5% and good sleep in 46.5%. Poor sleep quality as indicated by PSQI score >5 was reported in 63.5% of females and 42.9% of males which was statistically significant (P = 0.04). Out of these poor sleepers, 66.7% of males and 54.5% of females reported mobile phone usage for more than 2 up to 6 h. Comparatively, poor sleep quality was reported in only 19% of male students as compared to 27% of females among those using mobiles beyond 6 h. Besides, 14% of males and 18% of females among poor sleepers reported using mobiles <2 h. Further, in 80 respondents (Male: 40 and Female: 40) randomly selected for estimation of their early morning sample, serum melatonin level was estimated as 99.25 ± 72.07 pg/ml in males and 109.76 ± 84.54 pg/ml in females. Conclusion: Nearly 2/3rd of poor sleeper, 1st-year medical male students use mobiles for 2–6 h daily during the pandemic while Only ½ of the females do. However, among those poor sleepers using mobiles beyond 6 h daily, females outnumbered males. Estimated Serum smelatonin levels were also relatively higher than those reported in nonpandemic studies.
背景:新冠肺炎疫情已经在世界范围内强制执行了一种新常态,即日常生活和学术氛围都最大程度地依赖于技术。在全球范围内,学生受到了深刻的影响,但更具体地说,医学生承受着巨大的压力,这必然会影响他们的睡眠,从而影响睡眠调节激素——褪黑激素。因此,年轻的医学生在他们职业生涯的开端受到了不断变化的情况的打击,大多数课程都是在线的,越来越依赖于智能手机和笔记本电脑等科技产品。目的和目的:本研究的目的是确定一年级医学生的睡眠模式,调查他们的手机使用情况,并估计他们在COVID-19大流行期间的血清褪黑激素水平。材料与方法:本横断面研究在印度东北部医学研究所进行,采用标准问卷、匹兹堡睡眠质量指数(PSQI)和问题手机使用问卷对医学生进行调查,并采用ELISA法测定其清晨血清褪黑素水平。统计分析:收集的数据输入SSPS版本21,采用描述性措施进行分析,P < 0.05为统计学显著性。结果:101名18-23岁的大学生(男49岁,女52岁)参与了研究,其中睡眠质量差的占53.5%,睡眠质量好的占46.5%。63.5%的女性和42.9%的男性报告PSQI评分为bbb50分的睡眠质量较差,差异有统计学意义(P = 0.04)。在这些睡眠质量差的学生中,66.7%的男性和54.5%的女性报告使用手机超过2小时至6小时。相比之下,只有19%的男性学生报告睡眠质量差,而使用手机超过6小时的女性中有27%报告睡眠质量差。此外,在睡眠质量差的学生中,14%的男性和18%的女性报告使用手机<2小时。此外,在80名受访者中(男性:40,女性:40)随机选取的清晨样本,男性血清褪黑素水平估计为99.25±72.07 pg/ml,女性为109.76±84.54 pg/ml。结论:在流感大流行期间,近2/3睡眠不良的医一年级男生每天使用手机2-6小时,而女生只有1 / 2。然而,在每天使用手机超过6小时的睡眠不良者中,女性多于男性。估计的血清褪黑素水平也相对高于非大流行研究中报告的水平。
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引用次数: 0
Promoting active learning and student engagement in undergraduate medical education 在本科医学教育中促进积极学习和学生参与
Q4 Medicine Pub Date : 2022-05-01 DOI: 10.4103/jms.jms_140_21
S. Shrivastava, P. Shrivastava
Medical student is expected to acquire a significant amount of knowledge during their training period and this becomes major stress for them. The purpose of the current review was to understand the need for active learning and student engagement and identify the various tools or strategies to promote student engagement. An extensive search of all materials related to the topic was carried out on the PubMed search engine, and a total of 21 articles were selected based on their suitability with the current review objectives. Keywords used in the search include student engagement and medical education in the title alone only. Student engagement is a crucial aspect to ensure active learning as it aids in stimulating and enhancing the ability of students to comprehend the concepts and apply them. As we envisage interactive teaching should be the new norm in medical education delivery, it becomes a crucial factor that medical teachers should use appropriate tools/vignettes to ensure student engagement. To conclude, considering the complexities in medical education, ensuring student engagement during the teaching–learning session is of paramount importance. It becomes the responsibility of the teachers to employ various strategies and tools to engage students in the class, as it will help them to acquire knowledge and skills better and will eventually prepare them for their future competent medical practitioner.
医学生在训练期间需要获得大量的知识,这成为他们的主要压力。当前审查的目的是了解积极学习和学生参与的必要性,并确定促进学生参与的各种工具或策略。在PubMed搜索引擎上对与该主题相关的所有材料进行了广泛搜索,根据其与当前审查目标的适用性,共选择了21篇文章。搜索中使用的关键词仅在标题中包括学生参与度和医学教育。学生参与是确保积极学习的一个关键方面,因为它有助于激发和提高学生理解和应用概念的能力。由于我们认为互动教学应该成为医学教育提供的新规范,因此医学教师应该使用适当的工具/小插曲来确保学生的参与成为一个关键因素。总之,考虑到医学教育的复杂性,确保学生在教学过程中的参与至关重要。教师有责任采用各种策略和工具让学生参与课堂,因为这将帮助他们更好地获得知识和技能,并最终为他们未来的合格医生做好准备。
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引用次数: 0
Prospective clinical study to evaluate role of centchroman in regression of mastalgia in rural population 评价centchroman在农村人群乳房痛消退中的作用的前瞻性临床研究
Q4 Medicine Pub Date : 2022-05-01 DOI: 10.4103/jms.jms_115_21
S. Mishra, Somendra Singh, S. Singh, Vipin Gupta, P. Gupta, Anil Sharma, Shesh Kumar, M. Agarwal
Background: Mastalgia in the reproductive age group is common among women. Treatment is not yet standardized for these conditions. The majority of treatments used for mastalgia is costly and have side effects. The aim of our study was to find the efficacy of centchroman for regression of mastalgia in a predominantly rural population, measured by the visual analog scale (VAS). Materials and Methods: A total of 140 patients were randomized into two groups: Group 1 (n = 70) patients treated with centchroman and Group 2 (n = 70) patients treated with placebo for 12 weeks. The main outcomes are evaluated after one week to look for any intolerance, followed by repeated follow-ups at four, twelve, and twenty-four weeks to evaluate the treatment response using the VAS score and the side effects. Results: The mean age of patients in Group 1 was 29.63 ± 9.67 years and 32.32 ± 9.74 years in Group 2. The baseline mean VAS score was 6.40 ± 1.65 and 5.83 ± 1.69, respectively. After 2, 4, 8, 12, and 24 weeks of follow-up, the mean VAS score was significantly decreased in patients treated with centchroman. On intragroup comparison, the mean VAS score was significantly decreased at baseline to 2, 4, 8, 12, and 24 weeks of follow-ups. In both the groups, gastritis and headache were comparable, and delayed menstruation was significantly more in patients treated with centchroman. Conclusion: Centchroman has substantial efficacy, with a marginal effect on regression, of mastalgia in women of the reproductive age group, and it can be used as the first line of treatment.
背景:生殖年龄组的乳房疼痛在女性中很常见。这些情况的治疗尚未标准化。大多数用于治疗乳房痛的治疗方法成本高昂且有副作用。我们研究的目的是通过视觉模拟量表(VAS)测量centchroman在以农村为主的人群中对乳房痛消退的疗效。材料和方法:共140名患者被随机分为两组:第1组(n=70)接受centchroman治疗的患者和第2组(n=70%)接受安慰剂治疗12周的患者。一周后评估主要结果,以寻找任何不耐受,然后在第四周、第十二周和第二十四周重复随访,使用VAS评分和副作用评估治疗反应。结果:第一组患者的平均年龄为29.63±9.67岁,第二组为32.32±9.74岁。基线平均VAS评分分别为6.40±1.65和5.83±1.69。随访2、4、8、12和24周后,接受centchroman治疗的患者的平均VAS评分显著降低。在组内比较中,随访2、4、8、12和24周时,平均VAS评分在基线时显著降低。在这两组患者中,胃炎和头痛具有可比性,并且在接受centchroman治疗的患者中月经延迟明显更多。结论:Cenchroman对育龄妇女乳房痛有显著疗效,消退作用不大,可作为一线治疗药物。
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