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Fijación de las fracturas de cuello femoral del adulto: comparación retrospectiva entre tornillos canulados y el sistema de cuello femoral (FNS) 成人股骨颈骨折的固定:套管螺钉与股骨颈系统(FNS)的回顾性比较。
Q3 Medicine Pub Date : 2025-07-01 DOI: 10.1016/j.recot.2024.10.006
E. Guillén Botaya, Á. Soler García, J.L. Aparicio Martínez, A. Tejeda Gómez, F. Segura Llopis, A. Silvestre Muñoz

Objective

The FNS System DePuy Synthes® (EEUU, 2018) represents a recent alternative treatment for the fixation of femoral neck fractures, providing biomechanical advantages with respect to cannulated screws (3 CS). The objective of this study is to compare the clinical results of both fixation methods.

Method

A retrospective collection of the 36 subcapital fractures treated with the FNS system was carried out compared with a retrospective search of the last 35 patients treated with 3 CS. Age, sex, fracture pattern, delay until the intervention, length of intervention, hospital length stay, and haemoglobin loss were analyzed. In addition, the rate of avascular necrosis, nonunion, symptomatic femoral neck shortening, and material protrusion with or without its removal were recorded during a minimum follow-up of 6 months.

Results

No significant differences were found in age (p-value 0.32), fracture patterns (p-value 0.77), surgical delay (p-value 0.28), surgical time (p-value 0.226), length of hospital stay (p-value 0.921) and blood loss (p-value 0.086) between the two groups.
A significantly higher overall complication rate was observed in the group treated with cannulated screws (p-value 0.004). Analysed separately, a higher rate of avascular necrosis, symptomatic shortening of the femoral neck, protrusion of the osteosynthesis material with or without removal was observed in the group treated with cannulated screws.

Conclusions

The FNS system represents a safe and reproductible alternative for the fixation of femoral neck fractures, showing non-inferior outcomes to treatment with cannulated screws.
目的:FNS 系统 DePuy Synthes® (EEUU, 2018) 是最近用于股骨颈骨折固定的一种替代疗法,与套管螺钉(3CS)相比具有生物力学优势。本研究旨在比较两种固定方法的临床效果:方法:对使用 FNS 系统治疗的 36 例股骨颈下骨折患者进行回顾性收集,并与使用 3CS 治疗的最后 35 例患者进行回顾性检索。分析了患者的年龄、性别、骨折类型、介入治疗延迟时间、介入治疗时间、住院时间和血红蛋白损失。此外,在至少 6 个月的随访期间,还记录了发生血管性坏死、骨折不愈合、无症状股骨颈缩短以及材料突出(无论是否移除)的比率:两组患者在年龄(P 值 0.32)、骨折类型(P 值 0.77)、手术延迟(P 值 0.28)、手术时间(P 值 0.226)、住院时间(P 值 0.921)和失血量(P 值 0.086)方面均无明显差异。使用套管螺钉治疗组的总体并发症发生率明显更高(P 值为 0.004)。分别分析发现,使用套管螺钉治疗组的血管性坏死、股骨颈无症状缩短、骨合成材料突出(无论是否移除)的发生率较高:FNS系统是股骨颈骨折固定的一种安全、可重复的替代方法,其疗效不逊于带壳螺钉。
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引用次数: 0
La reparación aislada presenta mayor altura patelar postoperatoria según el índice de Insall-Salvati en comparación con la aumentación biológica en roturas agudas del tendón rotuliano 在急性髌腱断裂患者中,根据 Insall-Salvati 指数计算的孤立修复术后髌骨高度高于生物增强术。
Q3 Medicine Pub Date : 2025-07-01 DOI: 10.1016/j.recot.2024.10.002
R. Olivieri , J.T. Muñoz , J.I. Laso , J. Ugarte , N. Franulic , P. Innocenti
<div><h3>Background and objective</h3><div>Patellar tendon ruptures (PTR) are rare but highly disabling injuries. Surgical treatment is the standard approach. Postoperative patellar height (PH) is used to determine the success of the intervention, with various indices described in the literature. The objective of the study was to determine if there are differences in PH according to the Insall-Salvati index in the immediate postoperative period and at 4 months, between two groups of patients operated on for acute PTR: The first group underwent isolated repair techniques (IR) and the second group had biological augmentation with autograft or allograft added to the repair (BAR). Our hypothesis was that the BAR group would have lower PH in the immediate postoperative period and at 4 months.</div></div><div><h3>Materials and methods</h3><div>All patients with acute PTR treated at our center between 2016 and 2022 were reviewed retrospectively. Patients with re-rupture of the operated tendon and those with non-biological augmentation were excluded. PH according to the Insall-Salvati index was measured in radiographs taken the day after surgery and at 4 months postoperatively by three orthopedic surgeons with a subspecialty in knee surgery, independently. A fourth blind evaluator analyzed the measurement results, determining the average PH and the intraclass correlation coefficient for absolute agreement among the three evaluators. The primary outcome was the difference in PH between both groups the day after surgery and at 4 months. The secondary outcome was the difference in PH between the immediate postoperative measurement and at 4 months in both groups.</div></div><div><h3>Results</h3><div>This was a retrospective observational study. Thirty-one operated knees were included. IR was performed on 15 knees (48.38%), and biological augmentation was added in 16. The intraclass correlation coefficient between observer 1 and 2 was 0.88; between 2 and 3 it was 0.89; and between observers 1 and 3 it was 0.92, showing at least substantial agreement among observers. The average Insall-Salvati index the day after surgery and at 4 months was 1.15 and 1.21 for the IR group, and 0.97 and 1.07 for the BAR group, respectively. A statistically significant difference in the Insall-Salvati index was found between the two groups, both in the measurement taken the day after surgery (<em>p</em> <!--><<!--> <!-->0.0001) and at 4 months (<em>p</em> <!-->=<!--> <!-->0.0002). Additionally, significant differences were observed indicating an increase in average PH when comparing the immediate postoperative measurement and at 4 months in each study group (for IR <em>p</em> <!-->=<!--> <!-->0.0016 and for BAR <em>p</em> <!--><<!--> <!-->0.0001).</div></div><div><h3>Conclusions</h3><div>The Insall-Salvati index was significantly lower in BAR cases both the day after surgery and at 4 months postoperatively. Additionally, a significant increase in PH was observed at 4 months
背景和目的:髌腱断裂(PTR)是一种罕见的致残性损伤。手术治疗是标准方法。术后髌骨高度(PH)用于确定干预是否成功,文献中描述了各种指数。本研究的目的是根据 Insall-Salvati 指数,确定两组接受急性髌骨外翻手术的患者在术后初期和 4 个月后的髌骨高度是否存在差异。第一组患者采用孤立修复技术(IR),第二组患者在修复术中加入了自体或异体移植的生物增强技术(BAR)。我们的假设是,BAR 组在术后初期和 4 个月时的髌骨高度较低:回顾性研究了2016年至2022年期间在本中心接受治疗的所有急性PTR患者。排除了手术肌腱再次断裂的患者和非生物增高的患者。根据 Insall-Salvati 指数测量 PH 值,术后第二天和术后 4 个月的 X 光片由 3 位膝关节手术专业的骨科医生独立完成。第四位盲人评估员对测量结果进行分析,确定平均 PH 值和三位评估员之间绝对一致的类内相关系数 (ICC)。主要结果是两组患者术后第二天和 4 个月时 PH 值的差异。次要结果是两组术后即刻和 4 个月时 PH 值的差异:这是一项回顾性观察研究。共纳入了 31 个接受手术的膝关节。15个膝关节(48.38%)接受了IR手术,16个膝关节接受了生物增量术。观察者1和观察者2之间的ICC为0.88;观察者2和观察者3之间的ICC为0.89;观察者1和观察者3之间的ICC为0.92,这表明观察者之间的意见至少基本一致。IR组术后第二天和4个月时的平均Insall-Salvati指数分别为1.15和1.21,BAR组分别为0.97和1.07。两组的 Insall-Salvati 指数在术后第二天(p < 0.0001)和 4 个月时(p = 0.0002)的测量结果均有显著差异。此外,各研究组在术后即刻和 4 个月时的测量结果显示,平均 PH 值均有明显增加(IR 值 p = 0.0016,BAR 值 p < 0.0001):结论:在 BAR 病例中,术后第二天和术后 4 个月的 Insall-Salvati 指数都明显较低。此外,无论采用哪种手术方法,术后 4 个月时 PH 值均明显升高。在该组病例中,髌骨高度测量的观察者间一致性很高:证据等级:III。
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引用次数: 0
Impacto del alargamiento de miembros inferiores con clavos telescópicos en la funcionalidad y calidad de vida de pacientes con acondroplasia 软骨发育不全患者下肢伸长术对功能和生活质量的影响。
Q3 Medicine Pub Date : 2025-07-01 DOI: 10.1016/j.recot.2025.01.001
M. Galán-Olleros, J. Alonso-Hernández, C. Miranda-Gorozarri, J. García-Fernández, R.M. Egea-Gámez, Á. Palazón-Quevedo

Introduction

The short stature characteristic of patients with achondroplasia can negatively affect health-related quality of life (HRQoL). Lower limb lengthening reusing telescopic intramedullary nails (TIMNs) offers an alternative to external fixators, with the potential to enhance functionality, self-esteem, and HRQoL, while reducing complication risks, which this study aims to evaluate.

Materials and methods

This retrospective study included nine patients with achondroplasia who underwent parallel transverse lengthening of femurs and/or tibias reusing a TIMN between 2015 and 2022. Functionality (Lower Extremity Functional Scale, LEFS), self-esteem (Rosenberg Self-Esteem Scale), and HRQoL (Short Form-12, SF-12, and EuroQol VAS) were assessed preoperatively and at least two years post-surgery. Complications (Clavien-Dindo-Sink classification) and patient satisfaction were also recorded.

Results

The median age was 13.5 years (IQR: 12.5-17.1), with a significant height increase of +19.9 cm +19.9 cm (p < 0.05). Improvements were significant in functionality (LEFS, +4.6 points; p < 0.05), self-esteem (Rosenberg, +3.7 points; p < 0.05), and HRQoL (SF-12 physical, +8.9 points; p < 0.05; EQ-VAS, +20 points; p < 0.05). A total of 22 complications were reported in 32 treated bones, most classified as grade 2 or 3 B, with no significant correlation to functionality, HRQoL, or self-esteem outcomes (p > 0.05).

Conclusions

Lower limb lengthening reusing TIMNs appears to improve functionality, HRQoL, and self-esteem in patients with achondroplasia compared to their preoperative status. High patient satisfaction and manageable complications were observed, with no negative impact on outcomes, laying the groundwork for future studies.
软骨发育不全患者身材矮小的特点会对健康相关生活质量(HRQoL)产生负面影响。重复使用伸缩式髓内钉(timn)进行下肢延长是外固定架的另一种选择,具有增强功能、自尊和HRQoL的潜力,同时减少并发症的风险,本研究旨在对其进行评估。材料和方法:本回顾性研究纳入了9例软骨发育不全患者,这些患者在2015年至2022年间使用TIMN进行了股骨和/或胫骨平行横向延长。术前和术后至少两年评估功能(下肢功能量表,LEFS)、自尊(Rosenberg自尊量表)和HRQoL (Short Form-12、SF-12和EuroQol VAS)。同时记录并发症(Clavien-Dindo-Sink分类)和患者满意度。结果:中位年龄为13.5岁(IQR: 12.5 ~ 17.1),身高增加+19.9 cm +19.9 cm,差异有统计学意义(p < 0.05)。结论:与软骨发育不全患者术前相比,使用timn进行下肢延长似乎可以改善其功能、HRQoL和自尊。观察到患者满意度高,并发症可控,对结果无负面影响,为今后的研究奠定了基础。证据级别IV级,回顾性病例系列。
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引用次数: 0
Utilización de prótesis «cono de helado» en defectos acetabulares secundarios a resecciones tumorales 使用“冰锥”假体治疗肿瘤切除后的继发性眼睑缺陷
Q3 Medicine Pub Date : 2025-06-19 DOI: 10.1016/j.recot.2025.02.022
J. Teves, J. Perez-Abdala, N. Stramazzo, I. Albergo, G. Farfalli, M. Ayerza, L. Aponte-Tinao
<div><h3>Antecedentes y objetivos</h3><div>El tratamiento de tumores pélvicos, particularmente en la región periacetabular (zona <span>ii</span> de Enneking y Dunham), representa un gran desafío para los cirujanos ortopédicos oncológicos debido a la complejidad anatómica y a la necesidad de preservar la función de la cadera. Las prótesis tipo «cono de helado» han surgido como una opción reconstructiva prometedora por su versatilidad y su potencial para minimizar infecciones, aunque la evidencia sobre su efectividad aún es limitada.</div></div><div><h3>Materiales y métodos</h3><div>Se analizó una cohorte retrospectiva de pacientes con tumores óseos pélvicos tratados con prótesis tipo «cono de helado» entre 2016 y 2023 en un único centro de tercer nivel. Se incluyeron aquellos pacientes con afectación tumoral en la zona <span>ii</span> y preservación de zona Ia según la clasificación de Enneking. Se evaluaron variables quirúrgicas, complicaciones, funcionalidad, recurrencia y mortalidad.</div></div><div><h3>Resultados</h3><div>Diez pacientes cumplieron con los criterios de inclusión. La mediana de edad fue de 50 años, con un seguimiento promedio de 26,4 meses. El condrosarcoma fue el tumor más frecuente (60%). Todas las cirugías lograron márgenes oncológicos negativos. La mediana en la escala <em>Musculoskeletal Tumor Society</em> (MSTS) postoperatoria fue de 22,5 puntos (rango: 12-28). No se observó recurrencia local, aunque un paciente presentó metástasis y otro falleció por complicaciones de una enfermedad renal crónica.</div></div><div><h3>Conclusión</h3><div>La utilización de prótesis tipo «cono de helado» para defectos acetabulares secundarios a resección oncológica parece ser una técnica segura y eficaz en pacientes seleccionados, ofreciendo buenos resultados funcionales y alta satisfacción, con tasas de complicaciones comparables a otras alternativas.</div></div><div><h3>Background and objectives</h3><div>The treatment of pelvic tumors, particularly in the periacetabular region (zone II of the Enneking and Dunham classification), represents a significant challenge for orthopedic oncologic surgeons due to the anatomical complexity and the need to preserve hip function. “Ice cream cone” prostheses have emerged as a promising reconstructive option due to their versatility and potential to reduce infection rates, although evidence regarding their effectiveness remains limited.</div></div><div><h3>Materials and methods</h3><div>A retrospective cohort of patients with pelvic bone tumors treated with “ice cream cone” prostheses between 2016 and 2023 at a single tertiary care center was analyzed. Patients with tumors affecting zone II and undergoing preservation of zone Ia were included. Surgical variables, complications, functionality, recurrence, and mortality were evaluated.</div></div><div><h3>Results</h3><div>Ten patients met the inclusion criteria. The median age was 50 years, with a mean follow-up of 26.4 months. Chondrosarcoma was the most
骨盆肿瘤的治疗,特别是在腹股沟周围(Enneking和Dunham II区),由于解剖复杂性和保持髋关节功能的需要,对骨科肿瘤外科医生来说是一个巨大的挑战。“冰锥”式假体已经成为一种很有前途的重建选择,因为它的多功能性和减少感染的潜力,尽管关于其有效性的证据仍然有限。一组回顾性骨盆骨肿瘤患者在2016年至2023年期间在一个三级中心接受了“冰锥”假体治疗。根据Enneking分类,将肿瘤病变患者纳入II区和Ia区保留区。我们评估了手术变量、并发症、功能、复发和死亡率。10例患者符合纳入标准。中位年龄为50岁,平均随访26.4个月。软骨肉瘤是最常见的肿瘤(60%)。所有手术均达到负肿瘤边际。术后肌肉骨骼肿瘤学会(MSTS)量表的中位值为22.5(范围:12-28)。未观察到局部复发,但1名患者发生转移,1名患者死于慢性肾病并发症。结论:使用冰锥型假体治疗继发性肿瘤切除后的乙状结肠缺陷似乎是一种安全有效的技术,在选定的患者中提供了良好的功能结果和高满意度,并发症率可与其他替代方法相比较。骨盆肿瘤的治疗,特别是在腹股沟周区域(Enneking和Dunham分类的II区),由于解剖的复杂性和保持髋关节功能的需要,代表了骨科肿瘤外科医生的一个重大挑战。“冰淇淋锥”假体已经成为一种很有前途的重建选择,因为它们的多功能性和降低感染率的潜力,尽管关于它们有效性的证据仍然有限。对2016年至2023年在一家三级护理中心接受“冰淇淋锥”假体治疗的骨盆肿瘤患者回顾性队列进行了分析。包括影响II区和Ia区保存的肿瘤患者。对手术变量、并发症、功能、复发和死亡率进行了评估。结果10名患者符合纳入标准。中位年龄为50岁,平均随访时间为26.4个月。软骨肉瘤是最常见的肿瘤(60%)。所有的手术都达到了负肿瘤边际。肌肉骨骼肿瘤学会(MSTS)量表术后平均得分为22.5分(范围:12 - 28)。没有观察到局部复发,尽管一名患者出现转移,另一名患者死于慢性肾脏疾病的并发症。结论:使用“冰锥”假体治疗肿瘤切除后的乙酰片状缺陷似乎是一种安全有效的技术,在选定的患者中提供了良好的功能结果和高满意度,并发症率可与其他替代方法相比较。
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引用次数: 0
[Translated article] ‘À la carte’ treatment algorithm for patellofemoral instability 髌骨不稳的“À点菜”治疗算法
Q3 Medicine Pub Date : 2025-06-16 DOI: 10.1016/j.recot.2025.06.010
T. Pineda , D.H. Dejour
Patellar instability is a complex and multifactorial problem that poses difficulties in treatment decision-making. The treatment algorithm proposed by the Lyon School of Knee Surgery aims to guide surgeons in identifying imaging risk factors for failure and proposing a therapeutic plan focused on correcting major risk factors present in specific case.
髌骨不稳是一个复杂的多因素问题,给治疗决策带来困难。里昂膝关节外科学院提出的治疗算法旨在指导外科医生识别失败的影像学危险因素,并提出针对具体病例存在的主要危险因素进行纠正的治疗方案。
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引用次数: 0
[Translated article] Predictive factors of hospital and nursing facility admission in the fixation of low-energy ankle fractures 低能量踝关节骨折住院及护理机构住院的预测因素
Q3 Medicine Pub Date : 2025-06-16 DOI: 10.1016/j.recot.2025.06.014
J.V. Andrés-Peiró , M.M. Reverté-Vinaixa , O. Pujol-Alarcón , M. Altayó-Carulla , S. Castellanos-Alonso , J. Teixidor-Serra , J. Tomàs-Hernández , J. Selga-Marsà , C.A. Piedra-Calle , F. Blasco-Casado , Y. García-Sánchez , N. Joshi-Jubert , J. Minguell-Monyart

Introduction

Ankle fractures are increasingly common in frail patients, with hospitalisation being the principal cost driver, particularly for the elderly who often need referral to nursing facilities. This study aims to identify factors affecting resource utilisation per admission (hospital and nursing) in the fixation of low-energy ankle fractures.

Materials and methods

This retrospective cohort study examined patients undergoing fixation for low-energy ankle fractures. The primary outcome was the length of hospitalisation. Secondary outcomes included delays in fixation and the need for referral to a nursing institution. Multiple linear and logistic regression models were used to determine predictors related to patient demographics, injury characteristics, and treatment.

Results

We analysed 651 patients with a median age of 58 years. The median hospitalisation duration was 9 days, primarily before surgery. Extended hospitalisation was associated with antithrombotic treatment (b = 4.08), fracture-dislocation (2.26), skin compromise (7.56), complications (9.90), and discharge to a nursing centre (5.56). Referral to a nursing facility occurred in 17.2%, associated with older age (OR = 1.10) and an ASA score  III (6.96).

Conclusions

Prolonged hospitalisation was mainly due to surgical delays and was related to fracture-dislocations, skin compromise, and complications. Older and comorbid patients were more likely to need nursing facilities, and delays in these facilities’ availability contributed to extended hospital stays.
踝关节骨折在体弱患者中越来越常见,住院治疗是主要的成本驱动因素,特别是对于经常需要转介到护理机构的老年人。本研究旨在确定影响低能量踝关节骨折固定中每次住院(医院和护理)资源利用的因素。材料和方法本回顾性队列研究调查了接受低能量踝关节骨折固定治疗的患者。主要观察指标为住院时间。次要结果包括固定的延迟和转介到护理机构的需要。使用多元线性和逻辑回归模型来确定与患者人口统计学、损伤特征和治疗相关的预测因子。结果我们分析了651例患者,中位年龄58岁。中位住院时间为9天,主要是在手术前。延长住院时间与抗血栓治疗(b = 4.08)、骨折脱位(2.26)、皮肤损伤(7.56)、并发症(9.90)和出院到护理中心(5.56)相关。17.2%的患者转诊至护理机构,与年龄较大(OR = 1.10)和ASA评分≥III(6.96)相关。结论延长住院时间主要是由于手术延误,并与骨折脱位、皮肤受损和并发症有关。老年和合并症患者更可能需要护理设施,而这些设施的可用性延迟导致住院时间延长。
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引用次数: 0
[Translated article] Biomechanical study on cadaveric reconstruction with graft of the anterior talofibular and calcaneofibular ligaments 距腓骨前韧带和跟腓骨前韧带移植重建尸体的生物力学研究
Q3 Medicine Pub Date : 2025-06-16 DOI: 10.1016/j.recot.2025.06.008
A. Abarquero-Diezhandino , M.Á. Mellado-Romero , M. Muñoz de la Espada-López , R. Diaz-Suárez , E. García-Jarabo , A. Núñez-García , E.J. Sánchez-Morata , M.T. Vázquez-Osorio , F. Guerra-Pinto , J. Vilá-Rico

Background and aim

Ankle sprains can lead to chronic lateral ankle instability (CLAI) in 10-50% of cases. While the anterior talofibular ligament (ATFL) is traditionally considered the primary structure affected, recent studies indicate a high incidence of combined injuries to the ATFL and the calcaneofibular ligament (CFL). Given the importance of the CFL, this study aims to evaluate the biomechanical efficacy of double tendon graft reconstruction of the ATFL and CFL in cases of CLAI.

Materials and methods

This biomechanical study on cadaveric ankles compares two techniques: anatomical reconstruction using a double graft for both the ATFL and CFL versus isolated anatomical reconstruction of the ATFL with a single graft. Stability was assessed using specific examination maneuvers (anterior drawer, forced varus, and pivot shift) with an arthrometer measuring angular displacement across three spatial planes (horizontal, coronal, and sagittal). Four models were analyzed: intact ankle, sectioning of the ATFL and CFL, double graft reconstruction of the ATFL and CFL, and single graft reconstruction of the ATFL.

Results

The results showed no significant differences between the double graft reconstruction and the intact ankle. Comparing the double graft with the single graft reconstruction revealed statistically significant differences, favoring the double graft for greater angular stability in the coronal plane during forced varus and external rotation maneuvers.

Conclusions

Double graft reconstruction of the ATFL and CFL provides greater angular stability compared to isolated ATFL reconstruction, demonstrating significant benefits in lateral and rotational stabilization of the ankle in CLAI cases.
背景和目的在10-50%的病例中,踝关节扭伤可导致慢性外侧踝关节不稳定(CLAI)。虽然距腓骨前韧带(ATFL)传统上被认为是受影响的主要结构,但最近的研究表明,距腓骨前韧带和跟腓骨韧带(CFL)合并损伤的发生率很高。鉴于CFL的重要性,本研究旨在评估双肌腱移植重建ATFL和CFL在CLAI病例中的生物力学效果。材料和方法本生物力学研究比较了两种技术:使用双移植物对前fl和后fl进行解剖重建与使用单移植物对前fl进行分离解剖重建。使用关节计测量三个空间平面(水平面、冠状面和矢状面)的角位移,通过特定的检查动作(前伸、强制内翻和枢轴移位)评估稳定性。分析了四种模型:完整踝关节、前胫韧带和前胫韧带切片、前胫韧带和前胫韧带的双移植物重建和前胫韧带的单移植物重建。结果双植骨重建与踝关节完整无明显差异。双植骨重建与单植骨重建的比较显示出统计学上的显著差异,在强制内翻和外旋时,双植骨在冠状面具有更大的角度稳定性。结论与单独的ATFL重建相比,ATFL和CFL的双移植物重建提供了更大的角度稳定性,在CLAI病例中踝关节的侧向和旋转稳定方面显示出显著的益处。
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引用次数: 0
[Translated article] Induced osteogenesis by chitosan (3-glycidoxypropyl)trimethoxysilane and silica-based biomaterial in rabbits 壳聚糖(3-甘油氧基丙基)三甲氧基硅烷和硅基生物材料诱导家兔成骨
Q3 Medicine Pub Date : 2025-06-16 DOI: 10.1016/j.recot.2025.06.012
J. Orta-Chincoa , M. Salido , M. Piñero , N. García , P. Andrés-Cano

Introduction

Synthetic biomaterials obtained through tissue engineering offer an alternative to the use of autologous and heterologous grafts for the repair of bone defects of various etiologies, although the ideal material for this purpose has not yet been developed. A gel based on chitosan (CS) (3-glycidoxypropyl)trimethoxysilane (GPTMS), and silica have shown efficacy in experimental studies from a biomechanical and in vitro osseointegration perspective.

Objective

To demonstrate that the hybrid aerogel based on CS-GPTMS-silica is effective and safe for treating bone defects in load-bearing bone in rabbits.

Materials and methods

A comparative experimental study was conducted on 12 adult New Zealand rabbits, involving osteotomy in both radii as case (osteotomy with biomaterial placement) and contralateral control (osteotomy with placement of the extracted bone), both fixed with plates and screws. After 10 weeks, the animals were euthanized, and the surgical area was subjected to histological analysis.

Results

For all subjects, wound healing was successful, and normal gait was observed within 24–48 h. In case limbs, cortical closure of 95.9% was observed compared to 98% in control limbs. Residual biomaterial was observed in 5 subjects, with an average of 16% of the total analyzed area. Inflammatory cells were grouped (5–10%) in all case samples, with significant differences between case and control samples (p < .05). An increase in the presence of bone precursor cells (5–10%) was observed in all case samples compared to control samples, with significant differences (p < .05).

Conclusions

The aerogel based on chitosan CS-GPTMS, and silica is biocompatible and safe in rabbits, demonstrating minimal inflammatory reaction, good osteoblast adhesion, and a high resorption rate.
通过组织工程获得的合成生物材料为修复各种原因的骨缺损提供了自体和异体移植物的替代选择,尽管用于这一目的的理想材料尚未开发出来。基于壳聚糖(CS)(3-缩水氧基丙基)三甲氧基硅烷(GPTMS)和二氧化硅的凝胶从生物力学和体外骨整合的角度进行了实验研究。目的研究cs - gptms -二氧化硅复合气凝胶治疗家兔负重骨缺损的安全性和有效性。材料和方法对12只成年新西兰兔进行了对比实验研究,包括双侧桡骨截骨作为病例(截骨植入生物材料)和对侧对照(截骨植入取出的骨),均用钢板和螺钉固定。10周后,对动物实施安乐死,并对手术区域进行组织学分析。结果所有受试者伤口愈合成功,步态在24-48小时内恢复正常。病例肢体皮层闭合率为95.9%,对照组为98%。在5名受试者中观察到残留的生物物质,平均占总分析面积的16%。所有病例样本的炎症细胞分组(5-10%),病例与对照样本之间差异有统计学意义(p < 0.05)。与对照样本相比,在所有病例样本中观察到骨前体细胞的存在增加(5-10%),具有显著差异(p < 0.05)。结论壳聚糖CS-GPTMS和二氧化硅制备的气凝胶具有良好的生物相容性和安全性,炎症反应小,成骨细胞粘附良好,吸收率高。
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引用次数: 0
[Translated article] Superior capsular reconstruction of the shoulder with biceps autograft vs. Achilles allograft: A 2-year comparative study 【翻译文章】自体肱二头肌与异体跟腱肩关节上囊重建:2年对比研究
Q3 Medicine Pub Date : 2025-06-16 DOI: 10.1016/j.recot.2025.06.006
D.J. Gómez, S. Ávila Posada, N. Gabotto, G.M. Viollaz, Á.J. Muratore, N.N. Altamirano, D. Moya

Purpose

To retrospectively evaluate the clinical–functional outcomes, healing rates, complications, and surgical time in patients treated with superior capsular reconstruction (SCR) using long head of the biceps autograft (LHB) and Achilles allograft (AA).

Materials and methods

This retrospective study included 24 patients with irreparable rotator cuff tears of the supraspinatus and infraspinatus, treated with SCR. Two treatment groups were formed: one with 12 cases using AA and another with 12 cases using LHB. All patients were followed for a minimum of 2 years.

Results

The SSV was 73.7 ± 25.3 vs. 86.0 ± 8.7 (p = 0.26), the Constant score was 76.8 ± 20.1 vs. 83.7 ± 4.6 (p = 0.12), and the VAS was 1.6 ± 2.3 vs. 1.7 ± 0.5 (p = 0.9) for the LHB and AA groups, respectively. Tendon healing was 66.7% in AA and 100% in LHB (p = 0.001). Complications were 50% in AA and 0% in LHB. The average surgical time was 127.7 ± 37.6 min for AA and 84.3 ± 14.3 min for LHB (p = 0.01).

Conclusions

SCR with LHB showed better results in terms of tendon healing, fewer complications, and reduced surgical time compared to the use of AA.
目的回顾性评价采用自体肱二头肌长头移植(LHB)和跟腱同种异体移植(AA)进行上囊重建术(SCR)患者的临床功能、治愈率、并发症和手术时间。材料与方法本回顾性研究纳入24例应用SCR治疗的冈上和冈下不可修复的肩袖撕裂患者。治疗组分为两组,AA组12例,LHB组12例。所有患者至少随访2年。结果LHB组和AA组的SSV分别为73.7±25.3∶86.0±8.7 (p = 0.26), Constant评分分别为76.8±20.1∶83.7±4.6 (p = 0.12), VAS评分分别为1.6±2.3∶1.7±0.5 (p = 0.9)。AA组肌腱愈合率为66.7%,LHB组为100% (p = 0.001)。AA组并发症发生率为50%,LHB组为0%。AA的平均手术时间为127.7±37.6 min, LHB的平均手术时间为84.3±14.3 min (p = 0.01)。结论scr联合LHB与AA相比,在肌腱愈合方面具有更好的效果,并发症少,手术时间短。
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引用次数: 0
[Translated article] Use of artificial intelligence to predict complications in degenerative thoracolumbar spine surgery: A systematic review 使用人工智能预测退行性胸腰椎手术并发症:一项系统综述
Q3 Medicine Pub Date : 2025-06-16 DOI: 10.1016/j.recot.2025.06.015
G. Ricciardi , J.I. Cirillo Totera , R. Pons Belmonte , L. Romero Valverde , F. López Muñoz , A. Manríquez Díaz

Objective

We aim to conduct a systematic review of the literature to evaluate the effectiveness of artificial intelligence prediction models in predicting complications in adult patients undergoing surgery for degenerative thoracolumbar pathology compared with other commonly used prediction techniques.

Methods

A systematic literature review was conducted in Medline/Pubmed, Cochrane Library, and Lilacs/Portal de la BVS to identify machine learning models in predicting complications in patients undergoing surgery for degenerative thoracolumbar spine pathology between January 1, 2000, and May 1, 2023. The risk of bias was assessed using the PROBAST tool. Study characteristics and outcomes focusing on general or specific complications were recorded.

Results

A total of 2341 titles were identified (763 were duplicates). Screening was performed on 1578 titles, and 22 were selected for full-text reading, with 18 exclusions and 4 publications selected for the subsequent review. Additionally, 8 publications were included from other sources (Argentine Association of Orthopaedics and Traumatology Library; manual citation search). In 5 (41.6%) articles, the effectiveness of artificial intelligence predictive models was compared with conventional techniques. All were globally classified as having a very high risk of bias. Due to heterogeneity in samples, outcomes of interest, and algorithm evaluation metrics, a meta-analysis was not performed.

Conclusion

Although the available evidence is limited and carries a high risk of bias, the studies analysed suggest that these models may achieve promising performance in predicting complications, with area under the curve values mostly ranging from acceptable to excellent.
目的通过系统的文献综述,评价人工智能预测模型在预测成人退行性胸腰椎病变手术并发症方面的有效性,并与其他常用预测技术进行比较。方法系统回顾Medline/Pubmed、Cochrane Library和Lilacs/Portal de la BVS的文献,确定机器学习模型在预测2000年1月1日至2023年5月1日行退行性胸腰椎病变手术患者并发症中的应用。使用PROBAST工具评估偏倚风险。记录一般或特定并发症的研究特征和结果。结果共检出2341篇文献,其中重复文献763篇。对1578篇文献进行筛选,其中22篇入选全文阅读,18篇被排除,4篇入选后续综述。此外,从其他来源(阿根廷骨科和创伤学协会图书馆;人工引文检索)纳入了8份出版物。在5篇(41.6%)的文章中,人工智能预测模型与传统技术的有效性进行了比较。所有这些都被全球归类为具有非常高的偏倚风险。由于样本、感兴趣的结果和算法评估指标的异质性,没有进行meta分析。结论虽然现有的证据有限且存在较高的偏倚风险,但分析的研究表明,这些模型在预测并发症方面可能取得很好的效果,曲线下面积值大多在可接受到优秀之间。
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引用次数: 0
期刊
Revista Espanola de Cirugia Ortopedica y Traumatologia
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