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Funcionalidad del miembro inferior con exposición ósea con el uso de terapia con presión negativa VAC® vs. colgajo de gemelo medial VAC®负压治疗与内侧双胞胎皮瓣下骨暴露的下肢功能
Pub Date : 2023-03-31 DOI: 10.24265/horizmed.2023.v23n2.04
Enrique Antonio Chau Ramos
Objective: To compare two reconstructive surgery techniques for lower limb injury with exposed bone and demonstrate that the VAC® (vacuum-assisted closure) negative pressure wound therapy is an alternative for potential recovery showing no significant changes that could lead to functional compromise. Materials and methods: An analytical, prospective, quantitative and longitudinal study conducted with all the patients of Clínica Stella Maris with traumatic injuries of the lower limb and exposure of the middle third of the tibia treated with the VAC® system and the medial calf flap in 2019. Results: The measurement obtained with the functional ambulation categories (FAC) scale showed better results among the patients treated with the VAC® technique (since 50 % got grade V) than those who underwent the flap technique (50 % got grade IV), being the differences statistically significant (p < 0.05). It was observed that the time to closure was longer with the VAC® technique due to the progressive regeneration process consisting of the complete filling or coverage of the lesion area. On the other hand, the difference in the postoperative pain intensity between the two techniques was evident, being moderate to intense with the flap technique and mild, for the most part, with the VAC® technique. Conclusions: The VAC® suction system is effective for bone coverage in traumatic defects of the anterior middle third of the tibia. It is an alternative for potential recovery that does not change the anatomical structures because it provides better functional results and fewer complications. It is a useful and safe option that stimulates wound closure and minimizes the need for surgical treatment.
目的:比较两种下肢骨外露损伤的重建手术技术,并证明VAC®(真空辅助封闭)负压伤口治疗是一种潜在恢复的替代方法,没有明显的变化可能导致功能损害。材料与方法:对2019年所有采用VAC®系统和小腿内侧皮瓣治疗的Clínica Stella Maris下肢外伤性损伤及胫骨中三分之一外露患者进行分析性、前瞻性、定量和纵向研究。结果:功能活动分类(FAC)量表显示,采用VAC®技术治疗的患者(50%达到V级)优于采用皮瓣技术治疗的患者(50%达到IV级),差异有统计学意义(p < 0.05)。我们观察到,由于渐进式再生过程包括完全填充或覆盖病变区域,使用VAC®技术闭合的时间更长。另一方面,两种技术之间的术后疼痛强度差异是明显的,皮瓣技术是中等到强烈的,而VAC®技术在很大程度上是轻微的。结论:VAC®吸引系统对胫骨前中部三分之一创伤性缺损的骨覆盖是有效的。它是一种不改变解剖结构的潜在恢复方法,因为它提供了更好的功能结果和更少的并发症。这是一种有效和安全的选择,可以刺激伤口愈合,最大限度地减少手术治疗的需要。
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引用次数: 0
Percepciones de los estudiantes de ciencias de la salud sobre el aprendizaje cooperativo en la modalidad virtual 健康科学学生对虚拟模式下合作学习的看法
Pub Date : 2023-03-31 DOI: 10.24265/horizmed.2023.v23n2.03
Edith Chambi-Mescco, Ofelia Calero Escurra, Milagros Salazar De La Torre, Maritza Yovany Mestanza Tejada, Pilar Julia Paucar Miranda, Laura Ysabel Ballarta Rodríguez, Miguel Alfredo Durand Veramatus, Yolanda Segura Medina, Janet Cordori Carpio, Sara Pamela Sánchez Sandoval, Melisa Matos Carhuaricra
Objective: To identify the perceptions of implementing online cooperative learning during the 2021-II academic semester by first-year students of Universidad Nacional Mayor de San Marcos (UNMSM) School of Medicine. Materials and methods: A descriptive and cross-sectional research design was used in this study. The population consisted of 592 students from the professional schools of Human Medicine, Nursing, Obstetrics, Nutrition and
目的:了解圣马科斯国立大学(UNMSM)医学院一年级学生在2021-II学期实施在线合作学习的感受。材料和方法:本研究采用描述性和横断面研究设计。研究对象包括592名来自人类医学、护理学、产科、营养学和医学等专业学校的学生
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引用次数: 0
Apendicolito libre postapendicectomía
Pub Date : 2023-03-31 DOI: 10.24265/horizmed.2023.v23n2.11
Hubert James Mendoza Rojas
Dropped appendicolith following an appendectomy is a rare complication which may occur as a consequence of appendicolith expulsion from the appendix due to a previous perforation or failure to identify the appendicolith. A fecalith generally becomes symptomatic over time, as a result of abscess formation, intestinal obstruction, fistula tract or inflammation of the appendiceal stump. Two cases of dropped appendicolith following an appendectomy are described hereinbelow. Case 1: A 23-year-old female patient, who underwent an appendectomy the previous day, was admitted to the emergency room due to hypogastric pain. A computed tomography (CT) scan revealed a dropped appendicolith in the right iliac fossa, and a diagnostic laparoscopy showed intra-abdominal abscesses and a dropped appendicolith in the appendicular stump. Case 2: A 77-year-old male patient, who underwent surgery for acute appendicitis caused by appendicoliths, showed abdominal distension on the sixth postoperative day. The CT scan revealed intestinal obstruction and a dropped appendicolith at bowel loops. In the surgical reintervention, erosion of the mesentery caused by the appendicolith was evidenced. Both patients progressed after the reoperations. The incidence of dropped appendicolith following an appendectomy is currently unknown since few data are available in the literature worldwide. Therefore, it is important to present these cases to expand the casuistry, learn more about dropped appendicoliths following an appendectomy, demonstrate their complications if they are not removed early and show how to prevent them. In conclusion, dropped appendicoliths following an appendectomy must be removed early to avoid complications.
阑尾切除术后阑尾脱落是一种罕见的并发症,它可能是由于阑尾先前穿孔或未能识别阑尾而导致阑尾结石从阑尾排出的结果。随着时间的推移,由于脓肿形成、肠梗阻、瘘道或阑尾残端炎症,粪石通常会出现症状。本文描述了阑尾切除术后阑尾结石脱落的两个病例。病例1:23岁女性患者,前日行阑尾切除术,因下腹疼痛入院急诊。计算机断层扫描(CT)显示右侧髂窝阑尾结石脱落,诊断性腹腔镜检查显示腹腔内脓肿和阑尾残端阑尾结石脱落。病例2:男性,77岁,因阑尾结石引起的急性阑尾炎手术,术后第6天出现腹胀。CT扫描显示肠梗阻,肠袢处阑尾结石脱落。在手术再次介入治疗中,肠系膜糜烂是由阑尾炎引起的。两例患者在再次手术后均有进展。由于世界范围内的文献资料很少,阑尾切除术后阑尾结石脱落的发生率目前尚不清楚。因此,介绍这些病例是很重要的,以扩大诡辩,了解更多关于阑尾切除术后阑尾结石脱落的情况,说明如果不及早切除它们的并发症,并展示如何预防它们。总之,阑尾切除术后脱落的阑尾结石必须尽早切除以避免并发症。
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引用次数: 0
Uso y resultados del astegolimab en el manejo del asma severa: ¿qué se conoce? 阿斯替格单抗在严重哮喘治疗中的应用和结果:已知的情况?
Pub Date : 2023-01-31 DOI: 10.24265/horizmed.2023.v23n1.13
Iván David Lozada Martínez, Gonzalo Andrés Domínguez Alvarado, Fernando Torres Perez, Leidy Johanna Cruz Rodríguez, Lesmer Alirio Galindo Ruiz, María Camila Gamboa Perdomo, Luisa Fernanda Hurtado Quiros, Karen Elena Reales Hernández
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引用次数: 0
Asociación entre el nivel del establecimiento de salud y el cumplimiento de los elementos informativos en los formatos de consentimiento informado, 2019-2021 2019-2021年,卫生设施水平与知情同意格式中信息元素的依从性之间的关联
Pub Date : 2023-01-31 DOI: 10.24265/horizmed.2023.v23n1.01
José Luis Angeles Fuentes, Maritza Dorila Placencia Medina
El presente estudio forma parte del trabajo de investigación para obtener el Grado Académico de Magíster en Gerencia en Servicios de Salud: Angeles Fuentes, José Luis y Placencia Medina, Maritza, “Gestión del formato de consentimiento informado e instrumento de validación en los hospitales e institutos del Minsa de Lima Metropolitana 2019-2021” [tesis de posgrado]. Lima: Facultad de Medicina Humana, Universidad Nacional Mayor de San Marcos (UNMSM); 2022.
这项研究的研究工作的一部分来获取硕士学位在卫生服务管理:天使的来源、jose Luis和Placencia Medina,特鲁伊的知情同意和文书格式验证管理医院和首都利马的18岁学校2019-2021“研究生论文。利马:圣马科斯国立大学人类医学院(UNMSM);2022.
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引用次数: 0
Clases teóricas, ¿cosa del pasado en la docencia de ciencias básicas en Medicina? 理论课,医学基础科学教学的过去?
Pub Date : 2023-01-31 DOI: 10.24265/horizmed.2023.v23n1.00
Enrique Ruiz-Mori
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引用次数: 0
Compromiso del parénquima pulmonar secundaria a la inyección subcutánea de geles de silicona: reporte de caso 皮下注射硅胶凝胶继发性肺实质损伤:病例报告
Pub Date : 2023-01-31 DOI: 10.24265/horizmed.2023.v23n1.10
Renzo Steffano Valle Farfán, Enver Vantroi Palacios Ordoñez, Ysabel Lozano Rodas, Stefano Alessandro Valle Farfán
Pulmonary parenchymal involvement secondary to the subcutaneous injection of silicone gels is an unusual condition which occurs more frequently in women aged between 22 and 55 years. Although different theories have been put forward about its etiology, it is unknown and the condition may cause local and systemic complications and even have a fatal outcome. Few cases have been reported in South America and there is no report of this unique entity in Peru. We present the case of a previously healthy 28-year-old male transgender patient who, after an illegal subcutaneous injection of silicone gels in the gluteal region given by a non-healthcare professional, showed progressive respiratory distress and stabbing chest pain of approximately 7 out of 10 on the pain scale within the first 24 hours. Upon admission to the emergency room, respiratory failure was objectively evidenced since the patient had an oxygen saturation of 72 % at a FiO2 of 21 %, as well as pulmonary parenchymal involvement both in the CT scan and chest X-ray with signs highly suggestive of this pathology. Using a SARS-CoV-2 RNA real-time RT-PCR test performed on a respiratory specimen, COVID pneumonia, immunodeficiency disorders and pulmonary embolism were ruled out. Since there is no standard treatment, the patient was given relevant support measures such as the administration of supplemental oxygen at a low flow rate by binasal cannula, intravenous systemic corticosteroids and antibiotic therapy, thus achieving good progress with resolution of the initial clinical presentation. Then, after 10 days of intrahospital treatment, the patient was discharged.Copyright © La revista. Publicado por la Universidad de San Martin de Porres, Peru.
继发于皮下注射硅酮凝胶的肺实质受累是一种罕见的情况,多见于22至55岁的女性。虽然其病因有不同的说法,但尚不清楚,该病可引起局部和全身并发症,甚至致命。南美洲报告的病例很少,秘鲁也没有这一独特实体的报告。我们报告了一个先前健康的28岁男性变性患者,在由非医疗保健专业人员在臀部区域非法皮下注射硅凝胶后,在最初的24小时内表现出进行性呼吸窘迫和刺痛,疼痛等级约为7 / 10。在进入急诊室时,客观地证明了呼吸衰竭,因为患者的氧饱和度为72%,FiO2为21%,并且CT扫描和胸部x线检查显示肺实质受累,高度提示这种病理。通过对呼吸道标本进行SARS-CoV-2 RNA实时RT-PCR检测,排除了COVID -肺炎、免疫缺陷疾病和肺栓塞。由于无标准治疗,患者给予相应的支持措施,如双鼻插管低流速补氧、全身静脉注射糖皮质激素、抗生素治疗等,取得了良好的进展,初步临床表现得到缓解。经过10天的院内治疗,患者出院。版权所有©La revista。秘鲁圣马丁大学。
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引用次数: 0
Cáncer de mama y mutación del gen ataxia telangiectasia: reporte de caso 乳腺癌和共济失调基因突变毛细血管扩张:病例报告
Pub Date : 2023-01-31 DOI: 10.24265/horizmed.2023.v23n1.11
Óscar Alejandro Bonilla Sepúlveda
Among women, breast cancer is the most common cancer in the world, accounting for 25.7 % of all cancers and thus making it a topic of interest in public health. Breast cancer is a complex, heterogeneous genetic disease and, in the vast majority of cases, of unknown etiology. Around 7 % of breast cancer cases in the general population present a susceptibility gene mutation of Mendelian inheritance. The ataxia telangiectasia mutated (ATM) gene mutation is found in less than 1 % of the general population, and association studies conducted with controls have shown that these alleles are characterized by a moderate risk (RR: 2 ‐ 4) for hereditary cancer. Mutations in ATM incompletely cosegregate the disease, with an estimated 15 % of mutation carriers in this gene developing cancer. The incomplete penetrance of ATM, as well as other moderate‐risk genes, supports that they follow a polygenic model of cancer susceptibility. We report the case of a 35‐year‐old woman diagnosed with metachronous bilateral breast carcinoma—T4b N1 M0 stage IIIB left breast and T1c N0 stage I right breast, intrinsic luminal B subtype, HER2 overexpression and pathogenic variant of ATM gene c.7913 G>A, p. Trp2638*—who was treated with neoadjuvant chemotherapy, followed by mastectomy, sentinel node biopsy and radiotherapy. The objective of this case report is to describe the clinicopathological characteristics of breast cancer and its association with moderate‐risk gene mutations
在妇女中,乳腺癌是世界上最常见的癌症,占所有癌症的25.7%,因此使其成为公共卫生感兴趣的话题。乳腺癌是一种复杂的异质性遗传疾病,在绝大多数情况下,病因不明。一般人群中约7%的乳腺癌病例存在孟德尔遗传的易感基因突变。共济失调毛细血管扩张突变(ATM)基因突变在不到1%的普通人群中被发现,与对照进行的关联研究表明,这些等位基因具有中等遗传癌症风险(RR: 2‐4)。ATM的突变不完全共分离该疾病,估计有15%的该基因突变携带者会患上癌症。ATM和其他中等风险基因的不完全外显率支持它们遵循癌症易感性的多基因模型。我们报告一例35岁女性诊断为异时性双侧乳腺癌- t4b N1 M0 iii期ib左乳和T1c N0 I期右乳,内在腔内B亚型,HER2过表达和ATM基因c.7913的致病性变异G>A, p. Trp2638* -患者行新辅助化疗,随后行乳房切除术、前哨淋巴结活检和放疗。本病例报告的目的是描述乳腺癌的临床病理特征及其与中危基因突变的关系
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引用次数: 0
Factor de crecimiento nervioso en neuropatía óptica traumática 创伤性视神经病变中的神经生长因子
Pub Date : 2023-01-31 DOI: 10.24265/horizmed.2023.v23n1.09
Justiniano Oseas Zea Quispe, Roberto Michael Orihuela Echavigurin, Freddy Cristóbal López Gonzales
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引用次数: 0
Evaluación de la efectividad de la vitamina E en la esteatosis hepática no alcohólica en pacientes diabéticos tipo 2 sin fibrosis avanzada 维生素E治疗非晚期纤维化2型糖尿病患者非酒精性肝脂肪变性的有效性评价
Pub Date : 2023-01-31 DOI: 10.24265/horizmed.2023.v23n1.02
Gonzalo Miranda Manrique
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引用次数: 0
期刊
Horizonte Médico (Lima)
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