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La europeización de la genética y una mirada a los peruanos 遗传学的欧洲化和秘鲁人的一瞥
Pub Date : 2022-12-07 DOI: 10.24265/horizmed.2022.v22n4.00
Ricardo Fujita
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引用次数: 0
Riesgo de enfermedad cardiovascular y cerebrovascular a largo plazo en mujeres con antecedente personal de abrupción placentaria 有胎盘突变史的女性长期心血管和脑血管疾病的风险
Pub Date : 2022-12-07 DOI: 10.24265/horizmed.2022.v22n4.13
Iván David Lozada Martínez, María Teresa Navarro Peña, Adriana Isabel Castiblanco Cortes, Angela María Torres Villalobos, Juan Pablo Duque Varela, Natalia Bautista Motta, Carol Juliana Parra Navarro, Germán Felipe Aponte Vargas, Maickol Tocarruncho Tiria
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引用次数: 0
Hipertensión arterial asociada a osteoporosis en pacientes mujeres del hospital del Seguro Social, Trujillo 特鲁希略社会保险医院女性患者与骨质疏松症相关的动脉高血压
Pub Date : 2022-12-07 DOI: 10.24265/horizmed.2022.v22n4.04
Jeanpierre De La Cruz-Burgos, Víctor Bardales-Zuta
Objective: To determine if hypertension is associated with osteoporosis in female patients of Seguro Social de Salud (EsSalud) Hospital I in Trujillo. Materials and methods: An observational, analytical and cross-sectional study, which included 351 female patients treated in the Internal Medicine Unit of EsSalud Hospital I Florencia de Mora, Trujillo, from 2016 to 2019. According to the screening criteria, patients were divided into two groups—175 with hypertension and 176 without hypertension—to determine the number of patients with osteoporosis. The data was analyzed with Pearson’s chi-square test using IBM SPSS Statistics V26 to perform the statistical analysis and present the results in graphs and tables in Microsoft Excel Windows 10. Results: It was found that the prevalence of osteoporosis with hypertension accounted for 31.4 %, while that of osteoporosis without hypertension was 1.7 %. This shows that the prevalence of osteoporosis in women with hypertension is statistically significant ( p < 0.001) with respect to women without hypertension. Regarding the analysis of the intervening variables, age ( p < 0.001), cholesterol ( p < 0.001) and coffee ( p < 0.001) were statistically significant. Variables such as type 2 diabetes mellitus, sex, obesity, anemia, triglycerides and smoking were not statistically significant. Conclusions: Hypertension is associated with osteoporosis as well as with the intervening variables age, cholesterol and coffee, as they were statistically significant.
目的:了解特鲁希略市塞古罗社会医院(EsSalud)第一医院女性患者的高血压是否与骨质疏松症相关。材料与方法:一项观察性、分析性和横断面研究,纳入2016年至2019年在特鲁希略弗洛伦西亚德莫拉EsSalud医院内科治疗的351名女性患者。根据筛查标准,将患者分为高血压组175例和非高血压组176例,确定骨质疏松患者的数量。采用IBM SPSS Statistics V26对数据进行Pearson卡方检验进行统计分析,并在Microsoft Excel Windows 10中以图表形式呈现结果。结果:骨质疏松伴高血压的患病率为31.4%,骨质疏松无高血压的患病率为1.7%。这表明,与没有高血压的女性相比,高血压女性骨质疏松症的患病率具有统计学意义(p < 0.001)。对于干预变量的分析,年龄(p < 0.001)、胆固醇(p < 0.001)、咖啡(p < 0.001)具有统计学意义。2型糖尿病、性别、肥胖、贫血、甘油三酯和吸烟等变量无统计学意义。结论:高血压与骨质疏松相关,且与年龄、胆固醇、咖啡等干预变量相关,且具有统计学意义。
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引用次数: 0
Necesidad de inclusión de la enseñanza de medicina no convencional en la medicina convencional para la región de Sudamérica 需要将非传统医学教学纳入南美洲区域的传统医学
Pub Date : 2022-09-27 DOI: 10.24265/horizmed.2022.v22n3.00
A. Salazar-Granara
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引用次数: 0
Dolor osteoarticular y depresión en adultos mayores atendidos en un hospital geriátrico de Lima-Perú 利马-秘鲁老年医院治疗的老年人骨关节疼痛和抑郁
Pub Date : 2022-09-27 DOI: 10.24265/horizmed.2022.v22n3.03
Pamela Maceda Limo, Walter A. Maceda Nuñez, Esther A. Escalante López
Objective: To determine the relationship between osteoarticular pain and depression in older adults treated in a geriatric hospital in Lima, Peru. Materials and methods: An observational and descriptive study. A sample of 74 older adults treated in the outpatient department of a geriatric hospital in Lima, Peru, in 2021 was selected. A survey was used as technique and a questionnaire as instrument. Using the IBM SPSS Statistics statistical software, a chi-square test was performed with a significance level of 5 %. Results: Concerning the older adults’ general characteristics, 51.35 % were over 70 years of age, 55.41 % were women, 60.81 % had secondary education and 86.49 % were married or cohabiting. Regarding the characteristics of pain, 32.43 % stated that the pain decreased when they were not alone, 20.27 % pointed out that the pain was more intense at home, 81.08 % had moderate pain and 64.86 % had experienced pain for more than six months. As for depression, 43.24 % dealt with mild depression and 29.73 % had persistent depression. The characteristics of osteoarticular pain associated with depression were the degree of pain ( p = 0.041) and duration of pain ( p = 0.024). Conclusions: Osteoarticular pain was significantly associated with depression in older adults treated in a geriatric hospital in Lima, Peru.
目的:确定在秘鲁利马一家老年医院治疗的老年人骨关节疼痛和抑郁之间的关系。材料和方法:观察性和描述性研究。选取了2021年在秘鲁利马一家老年医院门诊部接受治疗的74名老年人作为样本。调查是一种技术,问卷是一种工具。采用IBM SPSS Statistics统计软件进行卡方检验,显著性水平为5%。结果:老年人总体特征中,70岁以上占51.35%,女性占55.41%,中等文化程度占60.81%,已婚或同居占86.49%。关于疼痛的特征,32.43%的人表示不独处时疼痛减轻,20.27%的人指出在家时疼痛更剧烈,81.08%的人疼痛中度,64.86%的人疼痛超过6个月。至于抑郁症,43.24%为轻度抑郁症,29.73%为持续性抑郁症。与抑郁相关的骨关节疼痛的特征为疼痛程度(p = 0.041)和疼痛持续时间(p = 0.024)。结论:在秘鲁利马一家老年医院接受治疗的老年人中,骨关节疼痛与抑郁症显著相关。
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引用次数: 0
Síndrome de POEMS: a propósito de un caso 诗歌综合症:关于一个案例
Pub Date : 2022-09-27 DOI: 10.24265/horizmed.2022.v22n3.10
Vianca Gutiérrez Araujo, Esther Hernández Santos, Luis Arturo Camacho Saavedra
POEMS syndrome is a disease of unknown pathogenesis. The acronym stands for the disease’s main clinical manifestations: polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin disorders. Recent studies suggest the association of genetic mutations with immunoglobulin λ. We report the case of a 56-year-old male patient with a 10-month clinical picture, whose initial signs and symptoms were lower limb edema and hypertrichosis, followed by gastrointestinal symptoms, inguinal lymphadenopathy and lower limb paresthesia. We emphasize the importance of this clinical case, given the limited reports of POEMS syndrome at the national level and no reported cases in the department of La Libertad, and the long time it takes to diagnose such disease.
POEMS综合征是一种病因不明的疾病。首字母缩略词代表了该疾病的主要临床表现:多神经病变、器官肿大、内分泌病变、单克隆伽玛病和皮肤病。最近的研究表明基因突变与免疫球蛋白λ有关。我们报告一例56岁男性患者,其临床表现为10个月,其初始体征和症状为下肢水肿和多毛,随后出现胃肠道症状,腹股沟淋巴结病和下肢感觉异常。我们强调这一临床病例的重要性,因为在国家一级对POEMS综合征的报道有限,La Libertad部门没有报告病例,而且诊断这种疾病需要很长时间。
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引用次数: 0
Factores asociados a la vacunación contra la COVID-19 en estudiantes de Medicina de una universidad peruana 秘鲁一所大学医科学生接种COVID-19疫苗的相关因素
Pub Date : 2022-09-27 DOI: 10.24265/horizmed.2022.v22n3.05
S. Dextre-Vilchez, R. Febres-Ramos, Sofia Raquel Dextre-Vilchez, M. R. Mercado-Rey
RESUMEN Objetivo: Determinar los factores asociados a la vacunación contra la COVID-19 en estudiantes de Medicina de la Universidad Peruana Los Andes. Materiales y métodos: Estudio observacional, analítico y transversal. Un total de 243 estudiantes del segundo al décimo ciclo respondieron un cuestionario que incluía características sociodemográficas, académicas, antecedentes médicos, familiares y personales, y el número de dosis recibidas de la vacuna contra la COVID-19. Para determinar la asociación, se utilizó las pruebas de chi cuadrado y t de Student. Resultados: La prevalencia de vacunación fue del 98,77 %, de los cuales el 61,73 % cuenta con las 3 dosis. Además, un 46,50 % de los estudiantes refirió haberse contagiado al menos una vez por la COVID-19. En el análisis bivariado se encontró que la edad (p = 0,047) y el lugar de residencia (p = 0,042) se asociaron de manera significativa con el estado de vacunación. Conclusiones: La prevalencia de vacunación fue muy alta; sin embargo, cabe resaltar que un número importante de estudiantes no recibió la dosis de refuerzo. Los factores asociados fueron la edad y la residencia. Se recomienda fomentar la vacunación en los estudiantes debido a la proximidad del retorno a las clases presenciales y su influencia en la opinión pública.
摘要目的:确定秘鲁洛斯安第斯大学医科学生接种COVID-19疫苗的相关因素。方法:采用观察性、分析性和横断面研究方法。共有243名二至十年级学生回答了一份问卷,问卷内容包括社会人口学、学术、病史、家庭和个人病史,以及接种COVID-19疫苗的次数。为了确定相关性,我们使用了卡方检验和学生t检验。结果:接种疫苗的流行率为98.77%,其中3剂接种疫苗的流行率为61.73%。此外,46.50%的学生报告至少感染过一次COVID-19。在双变量分析中发现,年龄(p = 0.047)和居住地(p = 0.042)与接种状态显著相关。结论:接种疫苗的流行率很高;然而,值得注意的是,相当多的学生没有接受强化剂量。相关因素包括年龄和居住地。建议鼓励学生接种疫苗,因为重返课堂的临近及其对公众舆论的影响。
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引用次数: 0
Lupus eritematoso sistémico ampolloso en un paciente varón de 16 años 16岁男性患者系统性水疱性红斑狼疮
Pub Date : 2022-09-27 DOI: 10.24265/horizmed.2022.v22n3.11
Karla Fiorella Aguilar García, Adela Margarita Vargas Rojas, Natalia Tena Angulo, Gabriela López Córdova, César Augusto Chian García, Wenceslao Castillo Farneschi
Bullous systemic lupus erythematosus (BSLE) is a vesiculobullous disease mediated by autoantibodies in patients with systemic lupus erythematosus (SLE). Tense vesicles and bullae are seen on an edematous, erythematous and sometimes normal skin in any body region, including mucous membranes and non-photoexposed areas. This is the case of a 16-year-old male patient with lupus nephritis who, on the seventh day of hospitalization, presented multiple serous and hemorrhagic blisters on the face, trunk, abdomen and upper extremities. The histological study showed a subepidermal bullous dermatosis with numerous neutrophils.
大疱性系统性红斑狼疮(BSLE)是一种由自身抗体介导的系统性红斑狼疮(SLE)患者的囊泡性疾病。在身体任何部位,包括粘膜和非光暴露部位,可在水肿、红斑和有时正常的皮肤上看到紧张的囊泡和大泡。这是一例16岁的男性狼疮肾炎患者,在住院第7天,在面部、躯干、腹部和上肢出现多个浆液和出血性水泡。组织学检查显示皮下大疱性皮肤病伴大量中性粒细胞。
{"title":"Lupus eritematoso sistémico ampolloso en un paciente varón de 16 años","authors":"Karla Fiorella Aguilar García, Adela Margarita Vargas Rojas, Natalia Tena Angulo, Gabriela López Córdova, César Augusto Chian García, Wenceslao Castillo Farneschi","doi":"10.24265/horizmed.2022.v22n3.11","DOIUrl":"https://doi.org/10.24265/horizmed.2022.v22n3.11","url":null,"abstract":"Bullous systemic lupus erythematosus (BSLE) is a vesiculobullous disease mediated by autoantibodies in patients with systemic lupus erythematosus (SLE). Tense vesicles and bullae are seen on an edematous, erythematous and sometimes normal skin in any body region, including mucous membranes and non-photoexposed areas. This is the case of a 16-year-old male patient with lupus nephritis who, on the seventh day of hospitalization, presented multiple serous and hemorrhagic blisters on the face, trunk, abdomen and upper extremities. The histological study showed a subepidermal bullous dermatosis with numerous neutrophils.","PeriodicalId":396953,"journal":{"name":"Horizonte Médico (Lima)","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123853688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Grado de dolor, trastornos musculoesqueléticos más frecuentes y características sociodemográficas de pacientes atendidos en el Área de Terapia Física y Rehabilitación de un centro médico de Villa El Salvador, Lima, Perú 在秘鲁利马萨尔瓦多维拉医疗中心物理治疗和康复领域接受治疗的患者的疼痛程度、最常见的肌肉骨骼疾病和社会人口学特征
Pub Date : 2022-09-27 DOI: 10.24265/horizmed.2022.v22n3.04
Alberto Guevara Tirado, Joseph Sanchez Gavidia
Objective: To describe the socioeconomic characteristics of, the most frequent pathologies and symptoms of, and the subjective pain assessment by patients treated at a physical therapy and rehabilitation center located in the district of Villa El Salvador, Lima, Peru. Materials and methods: A descriptive, prospective and cross-sectional study conducted in 366 patients over 18 years of age, of both sexes, who attended their first physical therapy. Results: The patients reported moderate pain intensity in the pre-physical therapy and rehabilitation sessions assessment. Low back pain was the most frequent pathology, followed by neck pain and painful shoulder. Regarding the education level, most patients had secondary and technical education. Moreover, a statistical association was found between pain intensity and sex (p = 0.049), as well as between pain intensity and profession/occupation (p = 0.012). Conclusions: The patients who attended the physical therapy and rehabilitation service reported moderate pain before beginning their sessions. Based on the results of the socioeconomic characteristics, it is necessary to keep up preventive and promotional health measures to avoid possible risk factors that exacerbate musculoskeletal disorders which may interfere with patients’ future recovery and possible relapse.
目的:描述在秘鲁利马维拉萨尔瓦多区物理治疗和康复中心接受治疗的患者的社会经济特征、最常见的病理和症状以及主观疼痛评估。材料和方法:一项描述性、前瞻性和横断面研究,对366名18岁以上、首次接受物理治疗的男女患者进行了研究。结果:在物理治疗前和康复期评估中,患者报告疼痛强度适中。腰痛是最常见的病理,其次是颈部疼痛和肩部疼痛。从受教育程度来看,大多数患者受过中等和技术教育。此外,疼痛强度与性别(p = 0.049)以及疼痛强度与专业/职业(p = 0.012)之间存在统计学关联。结论:参加物理治疗和康复服务的患者在开始治疗前报告了中度疼痛。根据社会经济特征的结果,有必要采取预防和促进健康措施,以避免可能加剧肌肉骨骼疾病的危险因素,从而干扰患者未来的康复和可能的复发。
{"title":"Grado de dolor, trastornos musculoesqueléticos más frecuentes y características sociodemográficas de pacientes atendidos en el Área de Terapia Física y Rehabilitación de un centro médico de Villa El Salvador, Lima, Perú","authors":"Alberto Guevara Tirado, Joseph Sanchez Gavidia","doi":"10.24265/horizmed.2022.v22n3.04","DOIUrl":"https://doi.org/10.24265/horizmed.2022.v22n3.04","url":null,"abstract":"Objective: To describe the socioeconomic characteristics of, the most frequent pathologies and symptoms of, and the subjective pain assessment by patients treated at a physical therapy and rehabilitation center located in the district of Villa El Salvador, Lima, Peru. Materials and methods: A descriptive, prospective and cross-sectional study conducted in 366 patients over 18 years of age, of both sexes, who attended their first physical therapy. Results: The patients reported moderate pain intensity in the pre-physical therapy and rehabilitation sessions assessment. Low back pain was the most frequent pathology, followed by neck pain and painful shoulder. Regarding the education level, most patients had secondary and technical education. Moreover, a statistical association was found between pain intensity and sex (p = 0.049), as well as between pain intensity and profession/occupation (p = 0.012). Conclusions: The patients who attended the physical therapy and rehabilitation service reported moderate pain before beginning their sessions. Based on the results of the socioeconomic characteristics, it is necessary to keep up preventive and promotional health measures to avoid possible risk factors that exacerbate musculoskeletal disorders which may interfere with patients’ future recovery and possible relapse.","PeriodicalId":396953,"journal":{"name":"Horizonte Médico (Lima)","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124864751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metástasis gástrica de tumor de células germinales mixto primario testicular: reporte de caso 睾丸原发性混合生殖细胞肿瘤胃转移:病例报告
Pub Date : 2022-09-27 DOI: 10.24265/horizmed.2022.v22n3.09
Fernando Barreda Bolaños, Jessica Alferez, Claudia Barreda Velit, Harold Benites Goñi, Luis Taxa Rojas
Testicular cancer is the most common solid tumor in men between ages 15 and 29. It can metastasize through the hematogenous or lymphatic routes to different organs such as the lung and liver (common) and the stomach (uncommon). We present the case of a 30-year-old male patient with upper gastrointestinal bleeding due to two ulcers in the stomach body with histology of unspecified small-cell malignant neoplasm. CT scans showed a right testicular tumor with secondary implants in the brain, lung, liver and spleen. β-HCG (35,5354 mIU/mL), AFP (500 ng/mL) and LDH (1,669 IU/L) tests were conducted. A right radical orchiectomy was performed. It is concluded that this was a clinical stage IIIC primary germ cell tumor of the right testis due to liver, spleen, lung, gastric and brain metastases.
睾丸癌是15至29岁男性中最常见的实体肿瘤。它可以通过血液或淋巴途径转移到不同的器官,如肺和肝脏(常见)和胃(不常见)。我们提出一个30岁的男性病人上消化道出血由于两个溃疡在胃体与组织学不明的小细胞恶性肿瘤。CT扫描显示右侧睾丸肿瘤,并在脑、肺、肝和脾继发植入。进行β-HCG(35、5354 mIU/mL)、AFP (500 ng/mL)、LDH (1669 IU/L)检测。行右侧根治性睾丸切除术。结论:本病例为临床IIIC期右侧睾丸原发性生殖细胞瘤,经肝、脾、肺、胃、脑转移。
{"title":"Metástasis gástrica de tumor de células germinales mixto primario testicular: reporte de caso","authors":"Fernando Barreda Bolaños, Jessica Alferez, Claudia Barreda Velit, Harold Benites Goñi, Luis Taxa Rojas","doi":"10.24265/horizmed.2022.v22n3.09","DOIUrl":"https://doi.org/10.24265/horizmed.2022.v22n3.09","url":null,"abstract":"Testicular cancer is the most common solid tumor in men between ages 15 and 29. It can metastasize through the hematogenous or lymphatic routes to different organs such as the lung and liver (common) and the stomach (uncommon). We present the case of a 30-year-old male patient with upper gastrointestinal bleeding due to two ulcers in the stomach body with histology of unspecified small-cell malignant neoplasm. CT scans showed a right testicular tumor with secondary implants in the brain, lung, liver and spleen. β-HCG (35,5354 mIU/mL), AFP (500 ng/mL) and LDH (1,669 IU/L) tests were conducted. A right radical orchiectomy was performed. It is concluded that this was a clinical stage IIIC primary germ cell tumor of the right testis due to liver, spleen, lung, gastric and brain metastases.","PeriodicalId":396953,"journal":{"name":"Horizonte Médico (Lima)","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128968354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Horizonte Médico (Lima)
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