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Regulation of a delicate problem in patients with rectal diseases 直肠疾病患者的一个微妙问题的调节
Pub Date : 2022-05-20 DOI: 10.21518/1995-1477-2022-19-1-81-88
V. Skvortsov, A. Eremenko, N. V. Eremenko
This paper highlights the problem of chronic constipation, their epidemiology, etiology, clinical features in some concomitant diseases, diagnostics and approaches to therapy with a focus on sodium picosulfate preparations. Based on several scientific papers, an analysis of a group of sodium picosulfate preparations was performed, indications, dosage, efficacy and possible side effects were considered. The paper also provides a clinical example of managing a patient with chronic constipation. Who received therapy with sodium picosulfate. Constipation is a violation of the act of defecation less than 3 times a week or more than three days. At the same time, it is possible to say about chronic constipation if such symptoms persist for 6 months. To date, the discussion about constipation as a nosological unit continues. The study of the epidemiology of constipation in various scientific sources indicates the wide spread of this disease. The diagnosis of “Constipation” is based on the Rome Criteria IV adopted in 2016. By origin, constipation can be primary and secondary, and among the factors provoking them are not only gastroenterological diseases, but diseases of other organ systems, as well as environmental factors and the intake of certain groups of medicines. Therapy of chronic constipation is carried out both medicamentally and non-medicamentally (surgical methods today have no proven effectiveness). The analysis of sodium picosulfate preparations proved their effectiveness and safety, which was also noted in our clinical case.
本文重点介绍了慢性便秘的问题、流行病学、病因、伴发疾病的临床特点、诊断方法和治疗方法,并重点介绍了pico硫酸钠制剂。根据多篇科学论文,对一组pico硫酸钠制剂进行了分析,考虑了适应症、剂量、疗效和可能的副作用。本文还提供了一个管理慢性便秘患者的临床实例。接受picosulfate钠的治疗。便秘是一种每周排便少于3次或超过3天的违规行为。同时,如果这样的症状持续6个月,就可以说是慢性便秘了。迄今为止,关于便秘作为一个分类学单位的讨论仍在继续。各种科学来源对便秘流行病学的研究表明,这种疾病的广泛传播。“便秘”的诊断基于2016年通过的罗马标准IV。从病因上看,便秘有原发和继发之分,引起便秘的因素不仅有肠胃疾病,还有其他脏器系统疾病,以及环境因素和某些药物的摄入。慢性便秘的治疗包括药物治疗和非药物治疗两种方法(目前尚未证实手术方法有效)。pico硫酸钠制剂的分析证明了其有效性和安全性,这在我们的临床病例中也得到了注意。
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引用次数: 2
Osteoarthritis: modern possibilities of therapy 骨关节炎:现代治疗的可能性
Pub Date : 2022-05-20 DOI: 10.21518/1995-1477-2022-19-1-60-67
Y. Filatova, M. Ilyin, I. N. Soloviev
The article discusses the treatment of osteoarthritis (OA). In recent decades, ideas about the pathogenesis of OA have undergone significant changes. If at the dawn of the study OA was presented as a degenerative process associated with age, now that some immunological and genetic aspects of the disease have become known, the idea of the pathogenesis of OA has changed. Currently, there are clinical guidelines developed by professional communities that define approaches to the diagnosis and treatment of patients with OA. In Russia, the Association of Rheumatologists and Orthopedic Traumatologists in 2021 developed clinical guidelines for the management of patients with gonarthrosis and coxarthrosis, but currently no clear consensus has been developed in any of the treatment recommendations regarding the use of nutraceuticals and dietary supplements. While according to published studies of plant and botanical nutraceuticals developed from natural products, promising data on efficacy compared to placebo drugs and their potential for the treatment of patients with OA have been demonstrated. According to a study conducted by N.E. Lane et al., patients with OA regularly use supplements, as well as over-the-counter products in combination with prescription drugs, and the likelihood of using prescription products increases with increasing duration and severity of OA. And currently there is not enough knowledge and information about the possibilities of additional use of nutraceuticals in the treatment of patients. The article discusses the composition of the biologically active additive, which has anti-inflammatory, anti-catabolic and antiproliferative effects and can be considered as an addition to NSAIDs, chondroitin sulfate, glycosamine (sulfate or hydrochloride) and their combinations in OA. Type II collagen peptide, curcumin (curcuminoids 95%), black pepper extract (piperine) and Boswellia pilchata extract in clinical studies have demonstrated efficacy and safety in the treatment of patients with OA. A number of studies have also found a number of pleootropic effects. Effects such as anti-inflammatory, neuroprotective, immunomodulatory, cardioprotective and antitumor effects will be important in patients with comorbidity.
本文讨论骨关节炎(OA)的治疗方法。近几十年来,关于OA发病机制的观点发生了重大变化。如果在研究开始时,OA被认为是一种与年龄相关的退行性过程,那么现在我们已经了解了这种疾病的一些免疫学和遗传学方面,OA的发病机制已经改变了。目前,专业团体制定了临床指南,定义了OA患者的诊断和治疗方法。在俄罗斯,风湿病学家和骨科创伤学家协会于2021年制定了关节病和关节关节病患者管理的临床指南,但目前尚未就使用营养保健品和膳食补充剂的任何治疗建议达成明确的共识。根据已发表的从天然产品中开发的植物和植物营养保健品的研究,与安慰剂药物相比,其疗效和治疗OA患者的潜力的数据已经得到证实。根据N.E. Lane等人的研究,OA患者经常使用补充剂,以及非处方药与处方药联合使用,并且使用处方药的可能性随着OA病程和严重程度的增加而增加。目前还没有足够的知识和信息说明在治疗患者时额外使用营养药品的可能性。本文讨论了具有抗炎、抗分解代谢和抗增殖作用的生物活性添加剂的组成,可考虑作为非甾体抗炎药、硫酸软骨素、糖胺(硫酸或盐酸)及其联合治疗OA的添加剂。II型胶原肽、姜黄素(姜黄素95%)、黑胡椒提取物(胡椒碱)和乳香提取物在临床研究中已经证明了治疗OA患者的有效性和安全性。一些研究也发现了一些多效性效应。抗炎、神经保护、免疫调节、心脏保护和抗肿瘤等作用对合并症患者将是重要的。
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引用次数: 3
Modern markers of inflammatory process in surgical practice 外科实践中炎症过程的现代标记
Pub Date : 2022-05-20 DOI: 10.21518/1995-1477-2022-19-1-147-156
A. Morozov, A. Sergeev, S. Zhukov, N. S. Novikova, M. Belyak
Introduction. Currently, one of the important problems in surgery is the search for new markers of the inflammatory process to determine the prognosis of the disease, substantiate the need for surgical intervention and to assess the effectiveness of treatment.Aim. To evaluate the possibilities and prospects of using modern markers of the inflammatory process in the practice of a surgeon.Materials and methods. In the course of the present investigation we analyzed relevant sources of domestic and foreign literature on the topic of application and possibilities of use of modern inflammatory process markers in various fields of medicine. Information was collected from databases of ScienceDirect, Cyberleninka.ru, and PubMed.Results. Acute phase proteins, as markers of inflammation, are valuable tools in the diagnosis, treatment and prognosis of inflammatory diseases, as they are sensitive to systemic inflammation. Important criteria for the use of biomarkers of inflammation are: a low number of false positive results and the possibility of using the marker not only as an indicator of the disease, but also to determine the severity of the patient’s condition. In order to assess the presence of inflammation in clinical conditions, laboratories evaluate the concentrations of various acute phase proteins in plasma. Currently, the most relevant markers of inflammatory processes are: C-reactive protein; haptoglobin; presepsin is also an early indicator of inflammation; fibrinogen; serum amyloid A; a complement system containing key markers of inflammation. Determining them in the surgeon’s practice will allow you to predict the outcome of the disease and evaluate the results of treatment.Conclusion. At the moment, the determination of inflammatory markers helps in predicting the disease, planning treatment tactics, evaluating the effectiveness of therapy after surgery and in earlier diagnosis of severe conditions.
介绍。目前,寻找炎症过程的新标志物来确定疾病的预后、证实手术干预的必要性和评估治疗的有效性是外科研究的重要问题之一。评估在外科医生的实践中使用现代炎症过程标志物的可能性和前景。材料和方法。在本次调查过程中,我们分析了国内外有关现代炎症过程标志物在医学各个领域的应用和使用可能性的相关文献来源。信息收集自ScienceDirect、cyberlenink .ru和PubMed.Results数据库。急性期蛋白对全身性炎症反应敏感,作为炎症的标志物,在炎性疾病的诊断、治疗和预后中具有重要的价值。使用炎症生物标志物的重要标准是:假阳性结果的数量少,并且该标志物不仅可以作为疾病的指标,还可以确定患者病情的严重程度。为了在临床条件下评估炎症的存在,实验室评估血浆中各种急性期蛋白的浓度。目前,与炎症过程最相关的标志物有:c反应蛋白;结合珠蛋白;胃泌素也是炎症的早期指标;纤维蛋白原;血清淀粉样蛋白A;一个包含炎症关键标志的补体系统。在外科医生的实践中确定它们将使你能够预测疾病的结果并评估治疗结果。目前,炎症标志物的测定有助于预测疾病,规划治疗策略,评估手术后治疗的有效性以及早期诊断严重疾病。
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引用次数: 2
Influence of treatment methods on quality of life of patients with hemorrhoidal disease 治疗方法对痔疮患者生活质量的影响
Pub Date : 2022-05-20 DOI: 10.21518/1995-1477-2022-19-1-68-80
E. Zagriadskiǐ, A. M. Bogomazov, E. B. Golovko, M. V. Abritsova
Introduction. The effectiveness of the treatment of hemorrhoidal disease is based on the frequency of recurrence of hemorrhoid symptoms, the development of early and late postoperative complications, as well as the degree of patient satisfaction with the results of treatment. However, such an indicator as quality of life, which reflects the health of the patient, is not taken into account.Aim. Obtaining data on the influence of the method and type of treatment on the quality of life of patients suffering from acute or chronic hemorrhoids.Materials and methods. The analysis of the influence of the treatment method on the quality of life of patients suffering from acute or chronic hemorrhoids was carried out. The analysis included 1032 patients with stage I–IV hemorrhoids. The age of the patients was 44.8 ± 13.0 (18–94) years. The study included 509 (49.3%) men and 523 (50.7%) women.Results. Quality of life indicators before treatment in all groups are within the reference values, which is associated with adaptation of patients to the disease. After treatment, quality of life indicators naturally increase. However, in patients after hemorrhoidectomy, regardless of the nature of the technique, quality of life indicators are significantly lower than in patients of groups 1 and 2.Conclusions. Quality of life indicators in all groups before treatment are within the reference values and do not have statistically significant differences in the considered indicators. After the treatment, there is a statistically significant increase in the quality of life indicators in all scales. After hemorrhoidectomy, regardless of the nature of the technique, quality of life indicators are significantly lower than in patients of groups 1 and 2, which is associated with surgical trauma. Since the groups of patients are heterogeneous in terms of the stages of the disease, it can be assumed that for each stage of hemorrhoids, there is a subjective perception of the disease, which can be reflected in the quality of life indicators, which requires additional analysis of the results obtained.
介绍。痔疮病的治疗效果是根据痔疮症状的复发频率、术后早期和晚期并发症的发生情况以及患者对治疗结果的满意程度来判断的。但是,没有考虑到反映病人健康状况的生活质量等指标。获取关于治疗方法和类型对急慢性痔疮患者生活质量影响的数据。材料和方法。分析治疗方法对急慢性痔疮患者生活质量的影响。该分析包括1032例I-IV期痔疮患者。患者年龄44.8±13.0(18-94)岁。该研究包括509名(49.3%)男性和523名(50.7%)女性。各组治疗前生活质量指标均在参考值范围内,这与患者对疾病的适应程度有关。治疗后,生活质量指标自然提高。然而,在痔疮切除术后的患者中,无论技术性质如何,生活质量指标均明显低于1组和2组患者。各组治疗前生活质量指标均在参考值范围内,所考虑指标无统计学差异。治疗后,各量表的生活质量指标均有统计学上的显著提高。痔疮切除术后,不论采用何种技术,其生活质量指标均明显低于1组和2组患者,这与手术创伤有关。由于患者群体在疾病分期方面存在异质性,因此可以假设,对于痔疮的每个阶段,都存在对疾病的主观感知,这可以反映在生活质量指标中,这需要对所获得的结果进行额外的分析。
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引用次数: 1
Air plethysmography characteristic of the pathological segmental hypervolemia of the calf in patients with CVD clinical classes (CEAP) CVD临床分型(CEAP)患者小腿病理性节段性高血容量的空气容积图特征
Pub Date : 2022-05-20 DOI: 10.21518/1995-1477-2022-19-1-124-131
A. B. Sannikov, E. Shaydakov
Introduction. The involvement of pathological segmental venous hypervolemia of the lower leg in patients with varicose veins in the formation of chronic venous insufficiency (CVI) is an established fact, however, objective criteria for this pathohemodynamic phenomenon have not been definitively determined today.The purpose of the study. Determination by air plethysmography (APG) of the degree of functional disorders in the limb and establishment of significant criteria characterizing pathological segmental hypervolemia of the lower leg in patients with CVD of various clinical classes according to CEAP.Materials and methods. For the period from 2002 to 2019, 380 healthy individuals with no symptoms of chronic venous diseases and 896 patients with CVD were examined with the use of APG, with their distribution in accordance with the CEAR international classification as follows: C0–C1, C2–C3, C4–C6 clinical classes. To assess the intensity of venous blood flow, the following values were calculated: the maximum capacity of the leg veins (Venous Capacity – VC), the volume of their evacuation (Evacuation Volume – EV) for a set time, the maximum venous outflow (Maximum Venous Outflow – MVO), the ratio of these values on both limbs (Venous Capacity Index – VC1, Evacuation Volume Index – EVI, Maximum Venous Outflow Index – MVOI).Results. The most statistically significant and conjugate correlation data were obtained (expectation, mean square deviation, standard error of expectation, median and coefficient of variation) during the analysis in groups according to the characteristic VCI.Discussion. The obtained results allowed us to assert that APG is an informative functional method for diagnosing hemodynamic disorders in patients with lower limb CVD.Conclusion. The established criteria of the venous capacity index will allow in practice to give an objective characterization of the degree of change in hemodynamic disorders in patients with CVD before and after the treatment undertaken.
介绍。静脉曲张患者的下肢病理性节段性静脉高血容量参与慢性静脉功能不全(CVI)的形成是一个既定的事实,然而,这种病理血流动力学现象的客观标准目前尚未明确确定。研究的目的。通过空气体积描记仪(APG)测定肢体功能障碍程度,并根据CEAP建立不同临床类型CVD患者下肢病理性节段性高血容量的重要标准。材料和方法。2002 - 2019年,应用APG对380例无慢性静脉疾病症状的健康个体和896例CVD患者进行了检测,其分布符合CEAR国际分类:C0-C1、C2-C3、C4-C6临床分类。为了评估静脉血流量的强度,我们计算了以下数值:在一定时间内腿部静脉的最大容量(venous capacity—VC)、静脉的最大流出量(evacuation volume—EV)、最大静脉流出量(maximum venous outflow—MVO),以及这些数值在四肢上的比值(静脉容量指数—VC1、抽气量指数—EVI、最大静脉流出量指数—MVOI)。在分组分析中,根据特征vci,获得最具统计学意义和共轭相关的数据(期望、均方差、期望标准误差、中位数和变异系数)。结果表明,APG是诊断下肢cvd患者血流动力学障碍的一种信息丰富的功能方法。静脉容量指数的既定标准将允许在实践中给出CVD患者在治疗前后血流动力学障碍变化程度的客观表征。
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引用次数: 0
Experience of homeopathic ointment during the non-surgical treatment for acute hemorrhoids in the outpatient settings 顺势疗法软膏在门诊急性痔疮非手术治疗中的应用经验
Pub Date : 2022-05-20 DOI: 10.21518/1995-1477-2022-19-1-98-106
B. M. Belik, A. Kovalev
Introduction. The use of traditional anti-inflammatory and local anesthetic preparations during the non-surgical treatment of acute hemorrhoids is liable to cause the progression of serious side effects in patients.Purpose of the study. To evaluate the clinical efficacy of homeopathic ointment as the topical preparation in the complex treatment of patients with acute hemorrhoids on the outpatient settings.Materials and methods. The comparative analysis of the results of the non-surgical treatment was conducted and applied to 48 patients with acute hemorrhoids of 1–3 degrees, who were divided into two groups. In 23 patients (control group), traditional non-surgical treatment was conducted without the use of topical preparations. In 25 patients (the main group), traditional preparation therapy was supplemented with local treatment using homeopathic ointment.Results. In the patients of the main group, a faster regression of pain syndrome and other manifestations of the disease (itching, burning and discomfort in the anal canal, perianal edema) was noted in the dynamics of treatment, and higher values of quality of life parameters were recorded than in patients of the control group. In the main group, good and satisfactory treatment results were obtained in 23 (92.0%) patients, unsatisfactory – in 2 (8.0%) patients. In the control group, good and satisfactory treatment results were observed in 18 (78.3%) patients, unsatisfactory results – in 5 (21.7%) patients.Discussion. The maximum therapeutic effect with topical application of ointment was observed in patients with acute hemorrhoids of 2–3 degrees, the disease in which proceeded with a pronounced inflammatory-allergic component.Conclusion. Our results allow us to consider homeopathic ointment as an alternative topical preparation in the non-surgical treatment of acute hemorrhoids in outpatient settings in patients with serious contraindications to the use of traditional topical preparations.
介绍。急性痔疮非手术治疗过程中使用传统的抗炎和局麻制剂,容易引起患者严重副作用的发展。研究目的:目的评价顺势疗法软膏作为外用制剂在门诊复杂治疗急性痔疮患者中的临床疗效。材料和方法。对48例1 ~ 3度急性痔疮患者进行非手术治疗效果的对比分析,并将其分为两组。23例患者(对照组)采用传统的非手术治疗,不使用外用制剂。25例患者(主要组)在传统制剂治疗的基础上辅以局部顺势疗法软膏治疗。在主组患者中,在治疗动态中注意到疼痛综合征和其他疾病表现(肛管瘙痒,灼烧和不适,肛周水肿)的消退更快,并且记录的生活质量参数值高于对照组患者。主组疗效满意23例(92.0%),不满意2例(8.0%)。对照组18例(78.3%)患者治疗效果良好满意,5例(21.7%)患者治疗效果不理想。局部应用软膏治疗2-3度急性痔疮患者效果最佳,该疾病伴有明显的炎症-过敏成分。我们的研究结果允许我们考虑顺势疗法软膏作为急性痔疮非手术治疗的替代外用制剂,在门诊设置的严重禁忌症的患者使用传统的外用制剂。
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引用次数: 1
About the current situation with regard to the risks and prevention of venous thromboembolic complications after varicose vein surgery 关于静脉曲张术后静脉血栓栓塞并发症的危险及预防的现状
Pub Date : 2022-05-20 DOI: 10.21518/1995-1477-2022-19-1-157-160
V. Bogachev, K. Lobastov, A. A. Fokin, E. Shaydakov, E. Burleva, A. Krylov, V. Barinov, S. Belentsov, V. Soroka, R. Bredikhin, D. A. Rosukhovski, D. Borsuk, P. G. Gabay
.
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引用次数: 1
Сlinical case of treatment of superficial thrombophlebitis (unique in its originality) Сlinical浅表性血栓性静脉炎治疗1例(独创性独特)
Pub Date : 2022-05-19 DOI: 10.21518/1995-1477-2022-19-1-29-33
A. B. Sannikov
Among patients with varicose veins, superficial vein thrombophlebitis occurs in 4–59% of patients. Unfortunately, despite the large number of published official sources with recommendations for the treatment of vein thrombophlebitis in our daily clinical practice, we continue to meet not just with casuistic cases, but because of their absurdity, which are beyond reasonable understanding (the appointment of leeches, c auterization of veins with celandine, alcohol compresses and lotions with dimexide). This clinical case report describes the case of a 65-year-old patient who initially sought medical help from a local therapist due to the appearance of a single seal and hyperemia in the upper third of the lower leg. For two weeks, the patient tried to independently stop the inflammation with alcohol compresses. Due to the lack of a positive effect, the district therapist prescribed antibiotics and warming compresses with combined nonivamide/nicoboxil ointment. Two weeks later, with the progression of inflammation and multiple purulent wounds on the background of necrosis foci throughout the inner surface of the entire lower limb, the patient turned to our medical center. As a result, it took us more than two months to stop the inflammation and heal extensive purulent wounds with secondary tension. Treatment of vein thrombophlebitis in varicose veins has been developed in detail for a long time and in detail. The tactics of using conservative means and operational benefits depend on the localization, prevalence, acute or chronic course of the disease. The purpose of this publication is to focus the attention of specialists of a wide profile on a specific example from practice on the choice of methods of treatment of vein thrombophlebitis.
在静脉曲张患者中,4-59%的患者发生浅静脉血栓性静脉炎。不幸的是,尽管在我们的日常临床实践中有大量发表的官方资料提供了治疗静脉血栓性静脉炎的建议,但我们继续遇到的不仅是一针见血的病例,而且还因为它们的荒谬,超出了合理的理解(预约水蛭,用白熏菜消毒静脉,酒精压迫和二甲苯洗液)。本临床病例报告描述了一名65岁患者的病例,他最初因出现单一密封和下肢上三分之一充血而向当地治疗师寻求医疗帮助。在两周的时间里,患者试图通过酒精压迫来独立地停止炎症。由于缺乏积极的效果,地区治疗师开了抗生素和热敷联合非尼瓦胺/尼科博西软膏。两周后,随着炎症的进展和整个下肢内表面坏死灶背景下的多个化脓性伤口,患者转向我们的医疗中心。结果,我们花了两个多月的时间才止住了炎症,并治愈了继发性紧张的广泛脓性伤口。静脉血栓性静脉炎在静脉曲张中的治疗已经有了很长时间的详细研究。采用保守手段的策略和手术效果取决于疾病的部位、流行程度、急慢性病程。本出版物的目的是将专家的注意力集中在一个具体的例子,从实践中选择治疗静脉血栓性静脉炎的方法。
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引用次数: 0
Some features of compression therapy for varicose veins of the lower extremities of clinical class C2 according to CEAP 临床C2级下肢静脉曲张压迫治疗的特点
Pub Date : 2022-05-19 DOI: 10.21518/1995-1477-2022-19-1-13-18
V. Bogachev, B. Boldin, P. Turkin, M. N. Klyuchevskaya
Introduction. The main method of varicose vein disease treatment is surgical intervention. At the same time, there is a rather large group of patients who postpone surgical treatment indefinitely. In this situation, conservative measures come to the fore, the key one among which is compression therapy.Aim. Study of the immediate effect of compression therapy on venous outflow from the lower extremities in patients with varicose veins and the medium-term results of medical knitwear classes 1 and 2.Materials and methods. The study enrolled 64 patients (mean age 28.3 ± 2.2 years, mean BMI 25.3 ± 4.1) with large saphenous vein reflux to the upper third of the tibia. Blood flow return time and pump force were measured while walking without and with zero, class 1, and class 2 compression knitted garments on.Results and discussion. On photoplethysmography return times without and with zero compression were 18.4 ± 2.2 s and 18.9 ± 1.4 s (p = 0.62), tibial venous pump strength was 3.6 ± 0.3% and 3.4 ± 0.2% (p = 0.57). Wearing a class 1 knitwear significantly increased return time and lower leg muscle venous pump strength to 21.6 ± 1.9 sec and 6.2 ± 1.8% (p < 0.001). Grade 2 knitwear increased return blood-flow time and tibia musculo-venous pump strength to 28.2 ± 2.6 sec and 12.3 ± 1.6%, which was significantly higher (p < 0.001). Global quality of life index according to CIVIQ-14 at baseline and follow-up was 44.3 ± 4.6 and 17.8 ± 3.6 points respectively (p < 0.001) in the class 1 group. Compression Class II had a mean value of 45.1 ± 3.9 and 18.1 ± 4.3 (p < 0.001).Conclusion. In summary, the RAL class 2 standard compression knitted fabric shows better immediate correction of lower leg muscle venous pump function in patients with primary varicose veins compared to the class 1 compression knitted fabric. In the mid-term followup there were no differences in the elimination of initial venous specific symptoms and in the improvement of the global quality of life index between class I and class II knitwear.
介绍。治疗静脉曲张疾病的主要方法是手术干预。与此同时,有相当多的患者无限期推迟手术治疗。在这种情况下,保守措施就显得尤为重要,其中最关键的是压迫治疗。压迫治疗对静脉曲张患者下肢静脉流出的即时效果及医用针织品1、2类中期效果的研究。材料和方法。该研究纳入64例患者(平均年龄28.3±2.2岁,平均BMI 25.3±4.1),大隐静脉返流至胫骨上三分之一。在不穿、不穿、不穿0级、1级和2级压缩针织服装行走时,测量血流量恢复时间和泵力。结果和讨论。无压迫和无压迫的光容积脉搏波恢复时间分别为18.4±2.2 s和18.9±1.4 s (p = 0.62),胫骨静脉泵强度分别为3.6±0.3%和3.4±0.2% (p = 0.57)。穿着1类针织衫可显著增加返回时间和下肢肌肉静脉泵强度,分别为21.6±1.9秒和6.2±1.8% (p < 0.001)。2级针织品使回血时间和胫骨肌静脉泵强度分别提高28.2±2.6秒和12.3±1.6%,差异有统计学意义(p < 0.001)。1级组患者基线和随访时CIVIQ-14全球生活质量指数分别为44.3±4.6分和17.8±3.6分(p < 0.001)。压缩II级的平均值分别为45.1±3.9和18.1±4.3 (p < 0.001)。综上所述,与1级压缩针织物相比,RAL 2级标准压缩针织物对原发性静脉曲张患者下肢肌肉静脉泵功能的即时矫正效果更好。中期随访时,I类针织品与II类针织品在初始静脉特异性症状的消除和总体生活质量指数的改善方面无差异。
{"title":"Some features of compression therapy for varicose veins of the lower extremities of clinical class C2 according to CEAP","authors":"V. Bogachev, B. Boldin, P. Turkin, M. N. Klyuchevskaya","doi":"10.21518/1995-1477-2022-19-1-13-18","DOIUrl":"https://doi.org/10.21518/1995-1477-2022-19-1-13-18","url":null,"abstract":"Introduction. The main method of varicose vein disease treatment is surgical intervention. At the same time, there is a rather large group of patients who postpone surgical treatment indefinitely. In this situation, conservative measures come to the fore, the key one among which is compression therapy.Aim. Study of the immediate effect of compression therapy on venous outflow from the lower extremities in patients with varicose veins and the medium-term results of medical knitwear classes 1 and 2.Materials and methods. The study enrolled 64 patients (mean age 28.3 ± 2.2 years, mean BMI 25.3 ± 4.1) with large saphenous vein reflux to the upper third of the tibia. Blood flow return time and pump force were measured while walking without and with zero, class 1, and class 2 compression knitted garments on.Results and discussion. On photoplethysmography return times without and with zero compression were 18.4 ± 2.2 s and 18.9 ± 1.4 s (p = 0.62), tibial venous pump strength was 3.6 ± 0.3% and 3.4 ± 0.2% (p = 0.57). Wearing a class 1 knitwear significantly increased return time and lower leg muscle venous pump strength to 21.6 ± 1.9 sec and 6.2 ± 1.8% (p < 0.001). Grade 2 knitwear increased return blood-flow time and tibia musculo-venous pump strength to 28.2 ± 2.6 sec and 12.3 ± 1.6%, which was significantly higher (p < 0.001). Global quality of life index according to CIVIQ-14 at baseline and follow-up was 44.3 ± 4.6 and 17.8 ± 3.6 points respectively (p < 0.001) in the class 1 group. Compression Class II had a mean value of 45.1 ± 3.9 and 18.1 ± 4.3 (p < 0.001).Conclusion. In summary, the RAL class 2 standard compression knitted fabric shows better immediate correction of lower leg muscle venous pump function in patients with primary varicose veins compared to the class 1 compression knitted fabric. In the mid-term followup there were no differences in the elimination of initial venous specific symptoms and in the improvement of the global quality of life index between class I and class II knitwear.","PeriodicalId":398195,"journal":{"name":"Ambulatornaya khirurgiya = Ambulatory Surgery (Russia)","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126305394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
“Medical neo-education”: How can a surgeon prove his qualification? 《医学新教育》:外科医生如何证明自己的资格?
Pub Date : 2022-05-19 DOI: 10.21518/1995-1477-2022-19-1-8-10
D. S. Zubkov
,
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引用次数: 0
期刊
Ambulatornaya khirurgiya = Ambulatory Surgery (Russia)
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