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3D Printing Dressing in Treatment of Diabetic Ulcer: A Case-Series 3D打印敷料在糖尿病溃疡治疗中的应用:一个案例系列
Pub Date : 2022-09-30 DOI: 10.47363/jdrr/2022(4)157
Vito Michele Cassano, Cecilia Parra, Giovanni Bonino, A. Carlo
Diabetic foot syndrome is defined as infection, ulceration, or destruction of deep tissues of the foot (including bones) in a patient with diabetes mellitus. Complex and multifactorial management of diabetic foot ulcer is necessary to reduce costs and ensure faster healing and avoid limb amputation. In this, dressings play a key role in stimulating tissue repair. In the case series we present we have exper-imented with the use of 3D printing resorbable biopolymers gauze in diabetic vascular ulcers. In both cases the lesions healed with a period of around 3 months with signs of improvement in the bottom of the lesion as early as the fifteenth day
糖尿病足综合征被定义为糖尿病患者足部深部组织(包括骨骼)的感染、溃疡或破坏。糖尿病足溃疡的复杂和多因素管理是必要的,以降低成本,确保更快的愈合和避免截肢。在这种情况下,敷料在刺激组织修复中起着关键作用。在病例系列中,我们提出了在糖尿病血管溃疡中使用3D打印可吸收生物聚合物纱布的实验。在这两种情况下,病灶愈合大约需要3个月的时间,病灶底部早在第15天就有改善的迹象
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引用次数: 0
Nutritional and Anti-Diabetic Properties of Cookies Supplemented with Processed Phyllantus Amarus Leaf 加香桉叶饼干的营养和抗糖尿病特性
Pub Date : 2022-06-30 DOI: 10.47363/jdrr/2022(4)154
Akintoyese O Alabi
This study described the α-Glucosidase, α-amylase, antioxidant activity, and glycemic index of wheat - Phyllantus amarus cookies, using standard methods. It was also observed that these medicinal plants have the ability to inhibit α–amylase, α-glucosidase and reducing effect on the radical DPPH and glycemic index of the formulated cookies. The microbial count on Phyllantus amarus cookies showed that only total viable count between (2-5) 103 cfu/g shows re-sponse against the four samples tested, while Staphylococcus aureus (cfu/g), Coliform count (cfu/g), Fungi count (sfu/g) showed no response which is an ev-idence that these samples may be good for consumption. Physical characteris-tics; thickness, diameter, weight, spread ratio and hardness were also observed which ranged from 12.68mm- 14.37mm, 2.76mm - 2.90mm, 4.18g - 6.44g, 0.17- 0.21 and 8.13mm - 11.57mm respectively. The moisture, protein, ash, fat, fibre, carbohydrate contents of the control cookies (100% Wheat flour) were 5.08%, 14.60%, 1.63%, 20.75%, 1.78%, 57.95% respectively while that of wheat-Phyllantus amarus cookies ranged from 4.14 %- 4.83 %, 13.95 % - 15.92 %, 1.22 % - 2.15 %, 19.83 % - 21.40%, 2.70% - 3.38%, 56.64% - 60.38% respectively
本研究采用标准方法测定了小麦毛竹饼干的α-葡萄糖苷酶、α-淀粉酶、抗氧化活性和升糖指数。同时还观察到这些药用植物具有抑制α-淀粉酶、α-葡萄糖苷酶的能力,并对配方饼干的DPPH自由基和血糖指数有降低作用。毛竹饼干上的微生物计数结果显示,只有(2 ~ 5)103 cfu/g之间的活菌总数对4种样品有反应,而金黄色葡萄球菌(cfu/g)、大菌群(cfu/g)、真菌(sfu/g)没有反应,说明这些样品可能适合食用。物理特征;厚度、直径、重量、铺展比和硬度分别为12.68mm ~ 14.37mm、2.76mm ~ 2.90mm、4.18g ~ 6.44g、0.17 ~ 0.21和8.13mm ~ 11.57mm。对照饼干(100%小麦粉)的水分、蛋白质、灰分、脂肪、纤维和碳水化合物含量分别为5.08%、14.60%、1.63%、20.75%、1.78%、57.95%,小麦-毛竹饼干的水分、蛋白质、灰分、脂肪、纤维和碳水化合物含量分别为4.14% ~ 4.83%、13.95% ~ 15.92%、1.22% ~ 2.15%、19.83% ~ 21.40%、2.70% ~ 3.38%、56.64% ~ 60.38%
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引用次数: 0
Chronic Kidney Disease in Patients with Diabetes: Diabetic vs. Non-Diabetic Kidney Etiologies 糖尿病患者的慢性肾病:糖尿病与非糖尿病肾病病因
Pub Date : 2022-06-30 DOI: 10.47363/jdrr/2022(4)152
Qi Wang, Gaosi Xu
Diabetes mellitus is a growing burden on global healthcare. Although the definition of Diabetic Kidney Disease (DKD) is that the kidney disease due to type 1 or 2 diabetes, the clinical diagnosis of DKD remains controversial. The diagnosis of DKD is highly subjective, depending on the doctor’s judgment and experience. It is necessary to distinguish the non-diabetic kidney disease from DKD at an early time, however, it is also seems difficult and inefficient. Up to date, there is lack of the diagnostic flow diagram for the disease. In this mini-review, we for the first time focused to create a diagnostic workflow for the disease
糖尿病是全球医疗保健日益沉重的负担。虽然糖尿病肾病(DKD)的定义是由1型或2型糖尿病引起的肾脏疾病,但DKD的临床诊断仍存在争议。DKD的诊断是高度主观的,取决于医生的判断和经验。早期鉴别非糖尿病性肾病和DKD是必要的,但难度大,效率低。到目前为止,缺乏该病的诊断流程图。在这篇小型综述中,我们首次专注于创建该疾病的诊断工作流程
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引用次数: 1
Diabetic Cheiroarthropathy 糖尿病Cheiroarthropathy
Pub Date : 2022-06-30 DOI: 10.47363/jdrr/2022(4)153
Ali Alsmair
A 54-year-old man with type 2 diabetes mellitus presented with limitation of movement, flexion deformity and stiff skin of both hands. The diagnosis was suspected clinically. Both wrists MRI were requested, however only the right wrist MRI was obtained for financial conditions
一例54岁男性2型糖尿病患者,表现为双手活动受限、屈曲畸形和皮肤僵硬。临床有疑似诊断。要求双手腕MRI,但由于经济原因仅获得右手腕MRI
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引用次数: 0
Diabetic Retinopathy Trends in a Digital Screening Program of Eight and Half Years 8年半数字筛查项目中的糖尿病视网膜病变趋势
Pub Date : 2022-03-31 DOI: 10.47363/jdrr/2022(4)151
J. Ahmad
Objectives: To share the trending of Diabetic Retinopathy (DR) over eight and half years period digital screening program of DR in Bangladesh at a tertiary eye hospital. Methods: This study analyze 8 and 1/2 years (102 months, from July 2010 to December 2018) findings of a digital screening and subsequent grading programs of DR in a tertiary eye care centre. A total 45289 eyes of 22645 diabetic person underwent retinal photography.7818 (17.26%) retinal Photographs were excluded because of unassessable for grading remaining 37471 retinal photographs were analyzed. Screening was performed by non-mydriatic digital fundus camera. Optometrist & Ophthalmologist review of all photographs were done at three level of grading system. Evaluation of the percentage distribution of degree of retinopathy was done. Data analysis was done by SPSS software version 16.0. Results: A total of 22645 patients (64.12 % male,35.88 % female) with mean age of 55.58 ± 9.88 (±SD) years were under went DR screening during a 8.5 years period. Features of DR was found in 18958 of 37471 (50.59%) retinal photographs. Non-proliferative diabetic retinopathy (NPDR) was documented in 14457 of 37471 photographs (38.59 %), while 4501 of 37471 photographs (12.00%) showed proliferative diabetic retinopathy (PDR). Diabetic Macular Edema (DME) was found in 10788 (28.79 %) of total 37471 assessable photograph and (56.90 %) of a total 18958 DR. Conclusion: DR is highly prevalent among Bangladeshi patients. In order to provide a sensitive, cost effective and easily accessible DR screening, digital imaging is a useful means
目的:分享孟加拉国某三级眼科医院8年半以来糖尿病视网膜病变(DR)数字化筛查项目的发展趋势。方法:本研究分析了一家三级眼科保健中心8年半(102个月,2010年7月至2018年12月)的DR数字筛查和后续分级方案的结果。共对22645例糖尿病患者的45289只眼睛进行了视网膜摄影(17.26%)视网膜照片因无法评估而被排除,剩余的37471张视网膜照片被分析。采用无散瞳数码眼底相机进行筛查。验光师和眼科医生对所有照片的审查按三级分级系统进行。评估视网膜病变程度的百分比分布。采用SPSS 16.0软件进行数据分析。结果:在8.5年的时间里,共有22645例患者(男性64.12%,女性35.88%)接受了DR筛查,平均年龄为55.58±9.88(±SD)岁。37471张视网膜照片中有18958张(50.59%)发现DR特征。37471张照片中有14457张(38.59%)为非增生性糖尿病视网膜病变(NPDR),而37471张照片中有4501张(12.00%)为增生性糖尿病视网膜病变(PDR)。糖尿病性黄斑水肿(DME)在37471例可评估照片中有10788例(28.79%),在18958例DR中有56.90%。结论:DR在孟加拉国患者中非常普遍。为了提供一种灵敏、经济、方便的DR筛查,数字成像是一种有用的手段
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引用次数: 0
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Journal of Diabetes Research Reviews & Reports
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