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Wound Healing Activity of Propolis of West Algeria 阿尔及利亚西部蜂胶伤口愈合活性研究
Q4 Medicine Pub Date : 2018-10-17 DOI: 10.3166/PHYTO-2018-0075
M. Debab, F. Toumi-Benali, H. Salem
Propolis is a resinous substance that bees use todefend their colonies against any pathogen. It has beenused in traditional medicine since ancient times because ofits therapeutic properties. Pollen analysis of propolis of AinTrid has shown that the region of Ain Trid is rich in plantspecies visited by bees (31 genus identified) and that themajority of these species are considered as medicinal plants,which gives propolis an important place in wound healing.The study of the wound healing activity is carried out in vivoon theWistar rats divided into 3 groups: group 1 treated withpropolis ointment, group 2 treated with commercial cream,and group 3 considered as untreated. The duration of treatmentwas estimated to be 23 days. The results obtainedshowed that the group treated by propolis ointment showeda high cure rate, in which the percentage of wound closurereached up to 94.93% ± 5.29 in the group 1, while in thegroup 2 arrived to 79.97% ± 13.01, and in group 3 was72.55% ± 19.94. The results demonstrated also that the numberof days required to contract 50% of wound area wasdifferent among the groups, in the 12th day in group 1,16th day in group 2, and 18th day post wounding in group 3.These results have shown that propolis can be prepared andused in traditional medicine as a natural ointment for thetreatment of skin diseases in our region.
蜂胶是一种树脂状物质,蜜蜂用它来保护蜂群免受任何病原体的侵害。由于其治疗特性,自古以来就被用于传统医学。对AinTrid蜂胶的花粉分析表明,Ain Trid地区有丰富的蜜蜂到访的植物物种(已确定31属),这些物种中的大多数被认为是药用植物,这使蜂胶在伤口愈合中占有重要地位。对Wistar大鼠的伤口愈合活性进行了活体研究,分为3组:第一组用蜂胶软膏治疗,第二组用市售乳膏治疗,第三组视为未治疗。治疗时间估计为23天。结果表明,蜂胶软膏治疗组的治愈率较高,其中第一组伤口愈合率为94.93%±5.29,第二组伤口愈合百分率为79.97%±13.01,第三组伤口愈合百分比为72.55%±19.94。研究结果还表明,不同组之间收缩50%伤口面积所需的天数不同,第12天为第12天,第2组为第16天,第3组为第18天。这些结果表明,蜂胶可以作为一种天然软膏制备并在传统医学中用于治疗我地区的皮肤病。
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引用次数: 1
Essai de formulation de suppositoires et ovules à base de beurre de karité comme excipient 乳木果油作为赋形剂的栓剂和卵子配方试验
Q4 Medicine Pub Date : 2018-10-17 DOI: 10.3166/PHYTO-2018-0065
E. Djoko, L. T. Nague, R. Chougouo, D. Wouessidjewe
Le beurre de karité et le beurre de cacao présentent de grandes similitudes d’utilisation en cosmétique et en agroalimentaire. Nous avons voulu, dans la présente étude, rechercher les voies et moyens de l’utilisation du beurre de karité dans le secteur pharmaceutique pour la fabrication des suppositoires et des ovules. Des échantillons de beurre de karité produits dans la région nord du Cameroun ont été achetés sur le marché de Bafoussam (région ouest). Après l’analyse physique et chimique des échantillons, nous avons procédé à la recherche d’un améliorant qui, incorporé au beurre de karité, pourrait permettre d’obtenir un excipient compatible avec la fabrication des suppositoires et des ovules. Nous avons ainsi essayé successivement comme améliorant la cire blanche et la silice colloïdale aux taux respectifs de 1, 2, 4 et 6 %. Pour vérifier la pertinence de notre choix, nous avons fabriqué et soumis au contrôle deux médicaments témoins en utilisant d’une part le beurre de karité brut local et d’autre part le beurre de karité raffiné importé de France (laboratoire Aroma). À température ambiante, le beurre de karité brut était collant et huileux au toucher, avec une consistance pâteuse. Son point de fusion était de 34 °C. L’indice d’acide était de 1,56, l’indice d’ester de 170,98, l’indice de saponification de 181,84, l’indice de peroxyde de 2,90 et la densité de 0,90. Pour ce qui est de la recherche de l’améliorant, le meilleur résultat a été obtenu avec la silice colloïdale anhydre (AEROSIL® 200) à 4 %. Le nouvel excipient obtenu avait une consistance convenable et un point de fusion favorable (36 °C) à l’utilisation comme excipient pour suppositoires. Tous les médicaments témoins (suppositoires enfants de paracétamol dosés à 300 mg et ovules de métronidazole dosés à 500 mg) fabriqués aussi bien avec le beurre de karité brut local que le beurre de karité raffiné importé ont répondu favorablement aux tests pharmacotechniques prévus par la pharmacopée européenne. Ce résultat des tests pharmacotechniques nous permet de conclure que le beurre de karité renforcé par 4 % de silice colloïdale anhydre peut être valablement utilisé comme excipient pour suppositoires et ovules.
乳木果油和可可脂在化妆品和食品加工中有很大的相似之处。在本研究中,我们试图研究乳木果油在制药部门用于栓剂和卵子生产的方法和方法。喀麦隆北部地区生产的乳木果油样品是在Bafoussam(西部地区)市场购买的。在对样品进行物理和化学分析后,我们开始寻找一种改进剂,将其与乳木果油混合,可以获得一种与栓剂和卵子生产兼容的赋形剂。因此,我们分别以1、2、4和6%的比例测试了白蜡和胶体二氧化硅的改良效果。为了验证我们的选择的相关性,我们生产并控制了两种对照药物,一方面使用本地生乳木果黄油,另一方面使用从法国进口的精制乳木果黄油(Aroma实验室)。在室温下,生乳木果油摸起来又粘又油腻,呈糊状。它的熔点是34°C。酸指数为1.56,酯指数为170.98,皂化指数为181.84,过氧化指数为2.90,密度为0.90。在改进剂研究中,4%的无水胶体二氧化硅(AEROSIL®200)获得了最好的结果。新获得的赋形剂具有足够的一致性和良好的熔点(36°C),适合作为栓剂赋形剂使用。所有儿童证人(栓剂药物服用扑热息痛的定量测定甲硝唑的卵子和300毫克至500毫克)制造,还是与当地牛油果油原油进口的牛油果油精制了响应测试欧洲药典规定的药典。药理试验的结果使我们得出结论,经4%无水胶体二氧化硅增强的乳木果油可以有效地用作栓剂和卵泡的辅料。
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引用次数: 0
Inhibition of Protein Tyrosine Phosphatase 1B by Lutein Derivatives isolated from Mexican Oregano (Lippia graveolens) 从墨西哥牛至(Lippia graveolens)分离的叶黄素衍生物对蛋白质酪氨酸磷酸酶1B的抑制作用
Q4 Medicine Pub Date : 2018-10-17 DOI: 10.3166/PHYTO-2018-0074
R. Perez-Gutierrez
Methanol extract from Lippia graveolens (Mexican oregano) was studied in order to identify inhibitory bioactives for protein tyrosine phosphatase 1B (PTP1B). Known flavone as lutein (1), and another flavone glycoside such as lutein-7-o-glucoside (2), 6-hydroxy-lutein-7-ohexoside (3) and lutein-7-o-ramnoide (4) were isolated from methanol extract of aerial parts of the Lippia graveolens. All isolates were identified based on extensive spectroscopic data analysis, including UV, IR, NMR, MS and compared with spectroscopic data previously reported. These flavones were evaluated for PTP1B inhibitory activity. Among them, compounds 1 and 3 displayed potential inhibitory activity against PTP1B with IC50 values of 7.01 ± 1.25 μg/ml and 18.4 μg/ml, respectively. In addition, compound 2 and 4 showed moderate inhibitory activity with an IC50 value of 23.8 ± 6.21 and 67.8 ± 5.80 μg/ml respectively. Among the four compounds, luteolin was found to be the most potent PTP1B inhibitor compared to the positive control ursolic acid, with an IC50 value of 8.12 ± 1.06 μg/ml. These results indicate that flavonoids constituents contained in Lippia graveolens can be considered as a natural source for the treatment of type 2 diabetes.
研究了墨西哥牛至的甲醇提取物对蛋白酪氨酸磷酸酶1B(PTP1B)的抑制活性。从李皮地上部分的甲醇提取物中分离出已知的黄酮,如叶黄素(1)和另一种黄酮苷,如叶黄素-7-葡萄糖苷(2)、6-羟基-白藜芦醇-7-羟基糖苷(3)和叶黄素-7-胡萝卜素(4)。所有分离物都是基于广泛的光谱数据分析(包括UV、IR、NMR、MS)进行鉴定的,并与之前报道的光谱数据进行了比较。对这些黄酮类化合物的PTP1B抑制活性进行了评价。其中,化合物1和3对PTP1B表现出潜在的抑制活性,IC50值分别为7.01±1.25μg/ml和18.4μg/ml。此外,化合物2和4表现出中等的抑制活性,IC50值分别为23.8±6.21和67.8±5.80μg/ml。在这四种化合物中,木犀草素被发现是与阳性对照熊果酸相比最有效的PTP1B抑制剂,IC50值为8.12±1.06μg/ml。这些结果表明,李皮中含有的黄酮类成分可以被认为是治疗2型糖尿病的天然来源。
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引用次数: 1
Evaluation of the Preservative Properties of Origanum elongatum Essential Oil in a Topically Applied Formulation Under a Challenge Test 在挑战试验下评价牛至精油在局部应用配方中的防腐性能
Q4 Medicine Pub Date : 2018-10-09 DOI: 10.3166/PHYTO-2018-0067
S. Boukhira, F. Bousta, S. Moularat, A. Abdellaoui, Z. B. Ouaritini, D. Bousta
The aim of this study is to evaluate the preservative efficacy of Origanum elongatum essential oil in topical cream under a challenge test that was performed following the standard procedure proposed by the European Pharmacopoeia, using standardized microorganisms. Essential oil was analyzed by GC–MS (gas chromatography–mass spectrometry). The antimicrobial activity of this essential oil was investigated by agar diffusion methods and broth microdilution assay to determine the minimum inhibitory concentration of essential oil required for preservation. The results demonstrated that the preservation effect was effective at 2% (v/w) of Origanum elongatum essential oil in topical cream, satisfying criterion A against Staphylococcus aureus, Escherichia coli and Aspergillus brasiliensis. However, the essential oil was ineffective against Pseudomonas aeruginosa with a reduction of 102 within 7 days of challenge and no increase up to the 28th day and against Candida albicans in the challenge test. Carvacrol predominated (63.06%), followed by the two monoterpenes hydrocarbons: γ-terpinene (15.99%) and p-cymene (9.51%). Our study highlighted the preservative power of Origanum elongatum essential oil as an alternative solution to chemical preservatives.
本研究的目的是根据欧洲药典提出的标准程序,使用标准化的微生物进行挑战试验,以评估长藤精油在局部乳膏中的防腐效果。采用气相色谱-质谱联用技术对精油进行分析。采用琼脂扩散法和肉汤微量稀释法研究了该精油的抑菌活性,确定了保存所需的最低抑菌浓度。结果表明,在2% (v/w)的浓度下,外用乳膏保存效果良好,对金黄色葡萄球菌、大肠杆菌和巴西曲霉均达到A标准。然而,在攻毒试验中,精油对铜绿假单胞菌无效,攻毒后7天内降低102,到第28天没有增加,对白色念珠菌没有增加。其次是γ-萜烯(15.99%)和对伞花烃(9.51%)两种单萜烯类化合物。我们的研究强调了长叶牛萃精油作为化学防腐剂的替代方案的防腐能力。
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引用次数: 3
Quorum sensing : une nouvelle cible anti-infectieuse des plantes médicinales Quorum Sensing:药用植物的新抗感染靶点
Q4 Medicine Pub Date : 2018-10-04 DOI: 10.3166/PHYTO-2018-0042
A. Bouyahya, Fatima-Ezzahrae Guaouguaou, N. Dakka, Y. Bakri
Le quorum sensing (QS) est une communication bacterienne fondee sur des molecules-signaux ligands-recepteurs. Ces derniers sont des pheromones bacteriennes dites auto-inductrices secretees par les bacteries pour reguler certaines fonctions telles que la resistance aux antibiotiques et la formation de biofilms. Le dechiffrage moleculaire de ce systeme a permis de decortiquer de nouvelles cibles moleculaires contrebalancant ainsi les mecanismes de resistance pour lutter contre les maladies infectieuses. Les substances naturelles des plantes medicinales sont montrees efficaces contre les mediateurs du QS dans les dernieres annees. Elles peuvent inhiber, interferer ou sequestrer les auto-inducteurs du QS. Ainsi, elles peuvent supprimer les phenotypes qui en resultent tels que la bioluminescence et la formation de biofilms. Dans le present travail, nous discutons le systeme du QS et leur implication dans les maladies infectieuses, ainsi nous montrons leur importance comme cible therapeutique specifique de substances naturelles extraites des plantes medicinales.
群体感应(QS)是基于配体受体信号分子的细菌通信。后者是所谓的自诱导细菌酚酮,由细菌分泌以调节某些功能,如抗生素耐药性和生物膜的形成。该系统的分子脱壳允许分离新的分子靶点,从而平衡对抗传染病的抗性机制。近年来,药用植物中的天然物质已被证明对QS介质有效。它们可以抑制、干扰或阻断QS自身诱导剂。因此,它们可以去除由此产生的表型,如生物发光和生物膜的形成。在这项工作中,我们讨论了QS系统及其与传染病的关系,因此我们展示了它们作为从药用植物中提取的天然物质的特异性治疗靶点的重要性。
{"title":"Quorum sensing : une nouvelle cible anti-infectieuse des plantes médicinales","authors":"A. Bouyahya, Fatima-Ezzahrae Guaouguaou, N. Dakka, Y. Bakri","doi":"10.3166/PHYTO-2018-0042","DOIUrl":"https://doi.org/10.3166/PHYTO-2018-0042","url":null,"abstract":"Le quorum sensing (QS) est une communication bacterienne fondee sur des molecules-signaux ligands-recepteurs. Ces derniers sont des pheromones bacteriennes dites auto-inductrices secretees par les bacteries pour reguler certaines fonctions telles que la resistance aux antibiotiques et la formation de biofilms. Le dechiffrage moleculaire de ce systeme a permis de decortiquer de nouvelles cibles moleculaires contrebalancant ainsi les mecanismes de resistance pour lutter contre les maladies infectieuses. Les substances naturelles des plantes medicinales sont montrees efficaces contre les mediateurs du QS dans les dernieres annees. Elles peuvent inhiber, interferer ou sequestrer les auto-inducteurs du QS. Ainsi, elles peuvent supprimer les phenotypes qui en resultent tels que la bioluminescence et la formation de biofilms. Dans le present travail, nous discutons le systeme du QS et leur implication dans les maladies infectieuses, ainsi nous montrons leur importance comme cible therapeutique specifique de substances naturelles extraites des plantes medicinales.","PeriodicalId":39888,"journal":{"name":"Phytotherapie","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41616987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Hypolipidemic and Antioxidant Effects ofCitrullus colocynthisSeeds Oil in High-Fat Diets Induced Obese Rats 瓜籽油对高脂饮食诱导肥胖大鼠的降血脂和抗氧化作用
Q4 Medicine Pub Date : 2018-10-04 DOI: 10.3166/PHYTO-2018-0066
M. Sari, S. Nemmiche, Houcine Benmehdi, A. Amrouche, A. Hamadi, D. C. Sari
The purpose of the current study is to explore the prominent role of the fixed oil of Citrullus colocynthis seeds as a natural remedy to obesity. Wistar rats were subjected to different diets; one being an 8 week high-fat diet that was established to induce obesity in rats. The results from our experiment show a significant correction in body weight, blood parameters, and in particular, the total cholesterol, triglycerides, HDL-C (high-density lipoprotein cholesterol), and glycemia. There was also an improvement of the redox status shown by the significant increase in antioxidant vitamins levels and decrease in malondialdehyde contents as well as an increase in the hepatic enzymes activities in Citrullus colocynthis seeds oil treated rats compared to obese rats and olive oil treated rats. The results of this study demonstrated that Citrullus colocynthis seeds oil prompted a corrective effect in the antioxidant defense systems, restored insulin sensitivity, and improved lipid profile. To conclude, our study suggests thatCitrullus colocynthisseeds oil is a promising natural tool to combat obesity and its associated complications.
本研究的目的是探索柠檬籽固定油作为治疗肥胖的天然药物的突出作用。Wistar大鼠接受不同的饮食;一种是为诱导大鼠肥胖而建立的8周高脂肪饮食。我们的实验结果显示,体重、血液参数,特别是总胆固醇、甘油三酯、HDL-C(高密度脂蛋白胆固醇)和血糖都有显著的校正。与肥胖大鼠和橄榄油处理的大鼠相比,通过显著增加抗氧化维生素水平、降低丙二醛含量以及增加肝酶活性,也显示出氧化还原状态的改善。这项研究的结果表明,柠檬子油促进了抗氧化防御系统的纠正作用,恢复了胰岛素敏感性,并改善了脂质状况。总之,我们的研究表明,柠檬子油是一种很有前途的对抗肥胖及其相关并发症的天然工具。
{"title":"Hypolipidemic and Antioxidant Effects ofCitrullus colocynthisSeeds Oil in High-Fat Diets Induced Obese Rats","authors":"M. Sari, S. Nemmiche, Houcine Benmehdi, A. Amrouche, A. Hamadi, D. C. Sari","doi":"10.3166/PHYTO-2018-0066","DOIUrl":"https://doi.org/10.3166/PHYTO-2018-0066","url":null,"abstract":"The purpose of the current study is to explore the prominent role of the fixed oil of Citrullus colocynthis seeds as a natural remedy to obesity. Wistar rats were subjected to different diets; one being an 8 week high-fat diet that was established to induce obesity in rats. The results from our experiment show a significant correction in body weight, blood parameters, and in particular, the total cholesterol, triglycerides, HDL-C (high-density lipoprotein cholesterol), and glycemia. There was also an improvement of the redox status shown by the significant increase in antioxidant vitamins levels and decrease in malondialdehyde contents as well as an increase in the hepatic enzymes activities in Citrullus colocynthis seeds oil treated rats compared to obese rats and olive oil treated rats. The results of this study demonstrated that Citrullus colocynthis seeds oil prompted a corrective effect in the antioxidant defense systems, restored insulin sensitivity, and improved lipid profile. To conclude, our study suggests thatCitrullus colocynthisseeds oil is a promising natural tool to combat obesity and its associated complications.","PeriodicalId":39888,"journal":{"name":"Phytotherapie","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48537953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Actualités en phytothérapie 植物疗法新闻
Q4 Medicine Pub Date : 2018-10-01 DOI: 10.1007/s10298-008-0328-9
P. Goetz
{"title":"Actualités en phytothérapie","authors":"P. Goetz","doi":"10.1007/s10298-008-0328-9","DOIUrl":"https://doi.org/10.1007/s10298-008-0328-9","url":null,"abstract":"","PeriodicalId":39888,"journal":{"name":"Phytotherapie","volume":"6 1","pages":"258-260"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10298-008-0328-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48221118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
E pur si muove ! 它也在动!
Q4 Medicine Pub Date : 2018-10-01 DOI: 10.3166/PHYTO-2018-0080
P. Goetz
{"title":"E pur si muove !","authors":"P. Goetz","doi":"10.3166/PHYTO-2018-0080","DOIUrl":"https://doi.org/10.3166/PHYTO-2018-0080","url":null,"abstract":"","PeriodicalId":39888,"journal":{"name":"Phytotherapie","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44297486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Activité virucide in vitro d’un extrait de cyprès sur des virus humains et bovins 柏树提取物对人病毒和牛病毒的体外杀毒活性
Q4 Medicine Pub Date : 2018-10-01 DOI: 10.3166/PHYTO-2018-0064
I. Guinobert, V. Bardot, L. Berthomier, I. Ripoche, C. Faivre, L. Haddioui, H. Belkhelfa
L’objectif etait de realiser l’empreinte phytochimique par HPTLC et d’identifier par LC/MS les principaux composes d’un extrait hydroethanolique de cones frais de cypres (Cupressus sempervirens L.) puis d’evaluer l’activite virucide de cet extrait sur quatre virus infectant l’Homme et trois virus bovins. L’analyse phytochimique a montre la presence de tanins, de flavonoides, d’acides amines et de glucides. A 40 % (v/v), au contact des virus pendant 60 minutes a 37 °C, l’extrait a eu une activite virucide sur le coronavirus, le virus parainfluenza de type 3, le virus respiratoire syncytial bovin et le rotavirus bovin. A 80 % (v/v), l’extrait a eu une activite virucide sur le virus influenza A-H1N1, le rhinovirus et l’herpesvirus bovin de type 1. Ces resultats invitent a poursuivre les travaux sur cet extrait de cypres et a explorer ses effets antiviraux in vivo.
目的是通过HPTLC实现植物化学指纹,并通过LC/MS鉴定新鲜柏树锥(Cupressus sempervirens L.)的水乙醇提取物的主要成分,然后评估该提取物对四种人类病毒和三种牛病毒的杀毒活性。植物化学分析A显示存在单宁、类黄酮、氨基酸和碳水化合物。在37°C下与病毒接触60分钟后,40%(v/v)的提取物对冠状病毒、副流感病毒3型、牛呼吸道合胞病毒和牛轮状病毒具有杀毒活性。在80%(v/v)时,提取物对甲型H1N1流感病毒、鼻病毒和牛疱疹病毒1型具有杀毒活性。这些结果邀请我们继续研究这种柏树提取物,并探索其体内抗病毒作用。
{"title":"Activité virucide in vitro d’un extrait de cyprès sur des virus humains et bovins","authors":"I. Guinobert, V. Bardot, L. Berthomier, I. Ripoche, C. Faivre, L. Haddioui, H. Belkhelfa","doi":"10.3166/PHYTO-2018-0064","DOIUrl":"https://doi.org/10.3166/PHYTO-2018-0064","url":null,"abstract":"L’objectif etait de realiser l’empreinte phytochimique par HPTLC et d’identifier par LC/MS les principaux composes d’un extrait hydroethanolique de cones frais de cypres (Cupressus sempervirens L.) puis d’evaluer l’activite virucide de cet extrait sur quatre virus infectant l’Homme et trois virus bovins. L’analyse phytochimique a montre la presence de tanins, de flavonoides, d’acides amines et de glucides. A 40 % (v/v), au contact des virus pendant 60 minutes a 37 °C, l’extrait a eu une activite virucide sur le coronavirus, le virus parainfluenza de type 3, le virus respiratoire syncytial bovin et le rotavirus bovin. A 80 % (v/v), l’extrait a eu une activite virucide sur le virus influenza A-H1N1, le rhinovirus et l’herpesvirus bovin de type 1. Ces resultats invitent a poursuivre les travaux sur cet extrait de cypres et a explorer ses effets antiviraux in vivo.","PeriodicalId":39888,"journal":{"name":"Phytotherapie","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49265034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Astragale : Astragalus membranaceus Bunge (Fabaceae) 黄芪:黄芪(豆科)
Q4 Medicine Pub Date : 2018-10-01 DOI: 10.3166/PHYTO-2018-0069
K. Ghedira, P. Goetz
{"title":"Astragale : Astragalus membranaceus Bunge (Fabaceae)","authors":"K. Ghedira, P. Goetz","doi":"10.3166/PHYTO-2018-0069","DOIUrl":"https://doi.org/10.3166/PHYTO-2018-0069","url":null,"abstract":"","PeriodicalId":39888,"journal":{"name":"Phytotherapie","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41489583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Phytotherapie
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