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MULTI-DRUG RESISTANT ESCHERICHIA COLI AND THEIR SENSITIVITY TO ORAL FOSFOMYCIN IN URINARY TRACT INFECTIONS: A SINGLE-CENTER EXPERIENCE 多重耐药大肠杆菌及其对口服磷霉素在尿路感染中的敏感性:单中心经验
Q4 Medicine Pub Date : 2023-05-23 DOI: 10.52764/jms.23.31.2.1
Iqbal Haider, Sana Ullah, K. Bibi, Hammad Naeem, Hamza M Ali, Wazir Mohammad Khan
Objectives: To determine the frequency of Escherichia coli (E. Coli) with multi-drug resistance and sensitivity to oral Fosfomycin in urinary tract infections in a public sector hospital of Peshawar Pakistan.Material and Methods: A descriptive cross-sectional study with a convenient consecutive sampling technique at the Department of Medicine Khyber Teaching Hospital Peshawar. A total of 179 patients were recruited in the current study. Detailed history and examination were carried out followed by routine baseline investigations. Under rigorous aseptic settings, two clean midstream urine samples from patients exhibiting symptoms of a urinary tract infection were collected. These samples were then promptly transferred to the hospital laboratory for routine evaluation and E.Coli inoculation on culture media. Once E.Coli was detected, it was tested for antibiotic sensitivity and resistance against the antibiotics mentioned. The multi-drug resistant (MDR) strains were isolated and their sensitivity was checked against oral fosfomycin. All the variables of data were recorded in SPSS version 20. Descriptive and inferential statistics will be utilized to elaborate study findings.  Results: The mean age in this study was 37 years with a standard deviation was ±11.27.Seventy-three (41%) patients were males and 106 (59%) patients were females. One hundred and eleven (62%) patients had multidrug-resistant E.Coli among which oral Fosfomycin was sensitive in 108(97%) patients and was resistant in 3(3%) patients presenting with urinary tract infection.Conclusion: The multidrug-resistant E. coli strains are common in our setup. However, oral fosfomycin has documented sensitivity against these MDR strains of E. coli in the majority of UTI cases. Keywords: Multidrug-resistant Escherichia coli, Drug Sensitivity, Fosfomycin, urinary tract infection
目的:确定巴基斯坦白沙瓦公立医院尿路感染中对口服磷霉素具有多药耐药性和敏感性的大肠杆菌(E.coli)的频率。材料和方法:在白沙瓦开伯尔教学医院医学部采用方便的连续采样技术进行描述性横断面研究。本研究共招募了179名患者。进行详细的病史和检查,然后进行常规基线调查。在严格的无菌环境下,从出现尿路感染症状的患者身上采集了两份干净的中游尿液样本。然后将这些样本迅速转移到医院实验室进行常规评估,并在培养基上接种大肠杆菌。一旦检测到大肠杆菌,就对其进行抗生素敏感性和对上述抗生素的耐药性测试。分离出耐多药菌株,并对其口服磷霉素进行了敏感性检测。数据的所有变量均记录在SPSS版本20中。描述性和推断统计学将用于阐述研究结果。结果:本研究的平均年龄为37岁,标准差为±11.27。73名(41%)患者为男性,106名(59%)患者为女性。一百一十一名(62%)患者患有耐多药大肠杆菌,其中口服磷霉素对108名(97%)患者敏感,对3名(3%)尿路感染患者耐药。结论:耐多药大肠杆菌菌株在我们的装置中是常见的。然而,在大多数尿路感染病例中,口服磷霉素对这些耐多药大肠杆菌菌株具有敏感性。关键词:耐多药大肠杆菌;药物敏感性;磷霉素;尿路感染
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引用次数: 0
PERCEPTION OF FOURTH-YEAR MEDICAL STUDENTS REGARDING THEIR EDUCATIONAL ENVIRONMENT IN THE PEDIATRIC UNIT OF KHYBER TEACHING HOSPITAL 四年级医学生对开伯尔教学医院儿科教育环境的看法
Q4 Medicine Pub Date : 2023-05-23 DOI: 10.52764/jms.23.31.2.3
A. Munir, Sabahat Amir, Farooq Ahmad, Usman Mehboob, Aqeel Muhammed
Objectives: The study aimed to assess the students’ perception of the educational environment in the pediatric unit of Khyber teaching hospital using Dundee Ready Educational Environment Measures (DREEM).Material and Methods: This cross-sectional, questionnaire-based study was conducted at the Department of Child Health Khyber Teaching Hospital Peshawar, Pakistan, from May to November 2019. The sample size included 220 students fourth-year students. The study instrument was the DREEM questionnaire, which has 50 items that assess five do­mains. There are 50 items with 5 subscales and the maximum score is 200.  Descriptive statistics were used to calculate the mean and standard deviation of the DREEM and the five domainsResults: Of the 220 Students, 100 completed the questionnaire, resulting in a response rate of 45%. The total DREEM score was 113.14/200 (56.57%). The results showed that student’s perception of their learning environment was 27.31/48 (56.89%), the perception of teachers was 25.45/44 (57.84%), self-perception of their academics was 18.97/32 (59.28%), their perception of the atmosphere was 27.7/48 (57.7%), and social self-perception was 13.7/28 (48.96%).Conclusion: The study found that the atmosphere in the pediatric ward of Khyber Teaching Hospital was perceived positively by the students. However, the total DREEM score and points in the subdomains did not fall in the excellent category and remained one step below the highest rank. Therefore, there is room for improvement in the educational climate at the pediatric ward of Khyber Teaching Hospital.Keywords: Dundee Ready Educational Environment Measures (DREEM), educational environment measures. 
目的:采用邓迪教育环境测评(DREEM)评估开伯尔教学医院儿科学生对教育环境的感知。材料和方法:这项基于问卷的横断面研究于2019年5月至11月在巴基斯坦白沙瓦开伯尔教学医院儿童保健部进行。样本量包括220名四年级学生。研究工具是DREEM问卷,它有50个项目,评估5个主要问题。共50题,5个分量表,满分200分。采用描述性统计方法计算DREEM和5个域的均值和标准差。结果:在220名学生中,有100人完成了问卷调查,回复率为45%。DREEM总评分为113.14/200(56.57%)。结果表明:学生对学习环境的感知为27.31/48(56.89%),对教师的感知为25.45/44(57.84%),对学术人员的自我感知为18.97/32(59.28%),对氛围的感知为27.7/48(57.7%),对社会的自我感知为13.7/28(48.96%)。结论:本研究发现,开伯尔教学医院儿科病房气氛良好。然而,DREEM的总得分和子域得分并没有落入优秀的类别,仍然比最高排名低一步。因此,开伯尔教学医院儿科病房的教育环境还有改进的余地。关键词:邓迪教育环境措施(DREEM),教育环境措施
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引用次数: 0
FREQUENCY OF THE AGENESIS OF PALMARIS LONGUS AND FLEXOR DIGITORUM SUPERFICIALIS TENDONS AMONG INDIVIDUALS 个体掌长肌和指浅屈肌肌腱发育不全的频率
Q4 Medicine Pub Date : 2023-05-23 DOI: 10.52764/jms.23.31.2.9
N. Rafique, Anum Rafique, Hafsa Bint Bilal, Izzah Nawaz, Mohab O. M. Ali
Objective: To find out the frequency of hereditary absence of palmaris longus and flexor digitorum superficialis tendons among individuals visiting physiotherapy clinics of 2 hospitals in Pakistan.Methods: This cross-sectional study was conducted in Government hospitals in twin cities (Islamabad and Rawalpindi), Pakistan from September 2018 to March 2019. For examination, a standardized clinical Schaeffer's test and three additional tests were used for the assessment of palmaris longus (PL), and a standardized simple, and the modified test was used for flexor digitorum superficialis (FDS). Data were analyzed by using SPSS 23.Results: Out of 619 individuals, 51.7% were men and 48.3% women were examined. The mean age of males was 33.4 years ± 14.5 and of females 35.9 years ± 13.4. Palmaris longus muscle was absent in 49.3% of participants with bilateral absence being more common. Unilateral absence of the PL muscle was found to be more in the left hand. Its absence in the left hand was found more common in females than in males (11.7% females, 9.1% males). This research showed agenesis of PL is gender dependent. (p< 0.05), and no association was found among the standard FDS and PL tendon test, that is r (617) =0.046, p= 0.249.Conclusion(s): The absence of palmaris longus muscle is more frequently found in women and in the left hand. Agenesis of FDS is rare in individuals and has no association with agenesis of palmaris longus.Keywords: Association, agenesis, humans, muscle, population. 
目的:了解在巴基斯坦两家医院的理疗诊所就诊的患者中,掌长肌腱和指浅屈肌肌腱遗传性缺失的频率。方法:本横断面研究于2018年9月至2019年3月在巴基斯坦两个城市(伊斯兰堡和拉瓦尔品第)的政府医院进行。为了进行检查,标准化临床Schaeffer试验和三项额外试验用于评估掌长肌(PL),标准化简单改良试验用于指浅屈肌(FDS)。结果:619名受试者中,男性占51.7%,女性占48.3%。男性平均年龄为33.4岁±14.5岁,女性平均年龄为35.9岁±13.4岁。49.3%的参与者没有掌长肌,双侧缺失更为常见。发现单侧PL肌缺失的情况更多发生在左手。它在左手中的缺失在女性中比男性更常见(女性11.7%,男性9.1%)。这项研究表明PL的发育不全是性别依赖性的。(p<0.05),标准FDS和PL肌腱测试之间没有发现相关性,即r(617)=0.046,p=0.249。结论:掌长肌缺失在女性和左手中更常见。FDS发育不全在个体中是罕见的,并且与掌长肌发育不全无关。关键词:联想,发育不全,人类,肌肉,人群。
{"title":"FREQUENCY OF THE AGENESIS OF PALMARIS LONGUS AND FLEXOR DIGITORUM SUPERFICIALIS TENDONS AMONG INDIVIDUALS","authors":"N. Rafique, Anum Rafique, Hafsa Bint Bilal, Izzah Nawaz, Mohab O. M. Ali","doi":"10.52764/jms.23.31.2.9","DOIUrl":"https://doi.org/10.52764/jms.23.31.2.9","url":null,"abstract":"Objective: To find out the frequency of hereditary absence of palmaris longus and flexor digitorum superficialis tendons among individuals visiting physiotherapy clinics of 2 hospitals in Pakistan.\u0000Methods: This cross-sectional study was conducted in Government hospitals in twin cities (Islamabad and Rawalpindi), Pakistan from September 2018 to March 2019. For examination, a standardized clinical Schaeffer's test and three additional tests were used for the assessment of palmaris longus (PL), and a standardized simple, and the modified test was used for flexor digitorum superficialis (FDS). Data were analyzed by using SPSS 23.\u0000Results: Out of 619 individuals, 51.7% were men and 48.3% women were examined. The mean age of males was 33.4 years ± 14.5 and of females 35.9 years ± 13.4. Palmaris longus muscle was absent in 49.3% of participants with bilateral absence being more common. Unilateral absence of the PL muscle was found to be more in the left hand. Its absence in the left hand was found more common in females than in males (11.7% females, 9.1% males). This research showed agenesis of PL is gender dependent. (p< 0.05), and no association was found among the standard FDS and PL tendon test, that is r (617) =0.046, p= 0.249.\u0000Conclusion(s): The absence of palmaris longus muscle is more frequently found in women and in the left hand. Agenesis of FDS is rare in individuals and has no association with agenesis of palmaris longus.\u0000Keywords: Association, agenesis, humans, muscle, population.\u0000 ","PeriodicalId":39900,"journal":{"name":"Journal of Medical Sciences (Taiwan)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48384742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE DIAGNOSIS OF TUBERCULOUS MENINGITIS BY DETECTION OF MYCOBACTERIUM TUBERCULOSIS DNA IN CEREBROSPINAL FLUID USING PCR TECHNIQUE 应用PCR技术检测脑脊液结核分枝杆菌DNA诊断结核性脑膜炎
Q4 Medicine Pub Date : 2023-05-23 DOI: 10.52764/jms.23.31.2.7
Nizzam Uddin, Ghulam Abbas, A. Zar, A. Nabi
Objective: To determine the frequency of positive mycobacterial PCR technique in cerebrospinal fluid (CSF) in patients with suspected tuberculous meningitis.Materials and methods: A cross-sectional study was conducted in the Department of Medicine Khyber Teaching Peshawar KPK from June 2020 to June 2021 over patients above the age of 15 years having clinical suspicion of tuberculous meningitis with cerebrospinal fluid showing raised protein, increased lymphocytes, and low CSF sugar levels. After performing a lumbar puncture 2.5 ccs of CSF was collected in a special bottle and sent to the laboratory for detection of Mycobacterial Tuberculosis (MTB) DNA. Data were analyzed by SPSS version 26. Results were displayed in tables and graphs.Results: Out of the total 100 patients, 49 (49%) were male and 51 (51%) were female. The mean age of the patients was 47.16±16.5 years (16- 82 years). The mean CSF cell count was 626/ cm3, the CSF protein level was 188.5±87 gram/dl and the mean CSF glucose level was 46±10 mg/dl ranging from 30 to 66 mg/dl. Mycobacterial PCR was positive for mycobacterium DNA in 70% of patients and negative in 30% of patients. MTB PCR in cerebrospinal fluid showed a strong correlation with CSF protein levels (p-value <0.000)Conclusion: Due to the high prevalence of positive PCR for the detection of MTB, every patient with a lymphocytic predominant picture of CSF examination and high protein should undergo MTB PCR testing for Mycobacterium tuberculosis.KEYWORDSMycobacterium tuberculosis, meningitis, polymerase chain reaction, cerebrospinal fluid
目的:检测疑似结核性脑膜炎患者脑脊液中分枝杆菌聚合酶链式反应阳性率。材料和方法:2020年6月至2021年6月,在白沙瓦KPK开伯尔教学医学系对15岁以上临床怀疑患有结核性脑膜炎的患者进行了一项横断面研究,脑脊液显示蛋白质升高、淋巴细胞增加和CSF糖水平低。在进行腰椎穿刺后,将2.5ccs的CSF收集在一个特殊的瓶子中,并送往实验室检测结核分枝杆菌(MTB)DNA。数据采用SPSS版本26进行分析。结果显示在表格和图表中。结果:100例患者中,男性49例(49%),女性51例(51%)。患者的平均年龄为47.16±16.5岁(16-82岁)。平均CSF细胞计数为626/cm3,CSF蛋白水平为188.5±87 g/dl,平均CSF葡萄糖水平为46±10 mg/dl,范围为30至66 mg/dl。70%的患者的分枝杆菌DNA聚合酶链式反应呈阳性,30%的患者呈阴性。脑脊液中的MTB-PCR与CSF蛋白水平呈强相关性(p值<0.000)。关键词结核分枝杆菌、脑膜炎、聚合酶链式反应、脑脊液
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引用次数: 0
CHEMICAL ANALYSIS OF DIFFERENT BRANDS OF BOTTLED WATER WITH WORLD HEALTH ORGANIZATION (WHO) STANDARDS 按世界卫生组织(who)标准对不同品牌瓶装水进行化学分析
Q4 Medicine Pub Date : 2023-05-23 DOI: 10.52764/jms.23.31.2.13
Adeela Mustafa, Hasnain Azam, Sarmad Ayaz Khan, Hoor ul ain, Faryal Gul, M. Awais, -. Inayatullah
Abstract: Objective: To assess the quality and compare different brands of bottled drinking water with WHO standards.  Methods: This is a cross sectional descriptive study conducted in Peshawar, Pakistan in 2022. 14 brands of bottled water was selected randomly and two samples of each brand were analyzed for physiochemical parameters in the laboratory of Khyber medical college. Results: In our results the physiochemical parameters such as colour, odor, taste, turbidity, chloride, nitrate, total solids, calcium and sulphate of all samples were found within the of WHO standards. Conclusion: Our study concluded that the bottled drinking water of different brands available in Peshawar city is physiochemically fit for consumption as all the parameter tested were within the permissible limits of WHO. Key words: Bottled water, Drinking water, WHO water quality standards, Physiochemical parameters
摘要:目的:评价不同品牌瓶装饮用水的质量,并与世界卫生组织标准进行比较。方法:这是一项2022年在巴基斯坦白沙瓦进行的横断面描述性研究。随机抽取14个品牌的瓶装水,在开伯尔医学院实验室对每个品牌的两个样品进行理化参数分析。结果:在我们的结果中,所有样品的理化参数,如颜色、气味、味道、浊度、氯化物、硝酸盐、总固体、钙和硫酸盐均符合世界卫生组织标准。结论:我们的研究得出结论,白沙瓦市不同品牌的瓶装饮用水在理化性质上适合消费,因为测试的所有参数都在世界卫生组织的允许范围内。关键词:瓶装水、饮用水、世界卫生组织水质标准、理化参数
{"title":"CHEMICAL ANALYSIS OF DIFFERENT BRANDS OF BOTTLED WATER WITH WORLD HEALTH ORGANIZATION (WHO) STANDARDS","authors":"Adeela Mustafa, Hasnain Azam, Sarmad Ayaz Khan, Hoor ul ain, Faryal Gul, M. Awais, -. Inayatullah","doi":"10.52764/jms.23.31.2.13","DOIUrl":"https://doi.org/10.52764/jms.23.31.2.13","url":null,"abstract":"Abstract: \u0000Objective: To assess the quality and compare different brands of bottled drinking water with WHO standards. \u0000 Methods: This is a cross sectional descriptive study conducted in Peshawar, Pakistan in 2022. 14 brands of bottled water was selected randomly and two samples of each brand were analyzed for physiochemical parameters in the laboratory of Khyber medical college. \u0000Results: In our results the physiochemical parameters such as colour, odor, taste, turbidity, chloride, nitrate, total solids, calcium and sulphate of all samples were found within the of WHO standards. \u0000Conclusion: Our study concluded that the bottled drinking water of different brands available in Peshawar city is physiochemically fit for consumption as all the parameter tested were within the permissible limits of WHO. \u0000Key words: Bottled water, Drinking water, WHO water quality standards, Physiochemical parameters","PeriodicalId":39900,"journal":{"name":"Journal of Medical Sciences (Taiwan)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44850628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FREQUENCY OF HYPERURICEMIA IN TYPE 2 DIABETES MELLITUS PATIENTS WITH BMI >23 KG/M2- STUDY AT A TERTIARY CARE HOSPITAL BMI>23kg/M2的2型糖尿病患者高尿酸血症的发生频率&一家三级医院的研究
Q4 Medicine Pub Date : 2023-05-23 DOI: 10.52764/jms.23.31.2.4
Aqil Noor, Shaista Kanwal, Suleman Elahi Malik, Zafran Ullah, T. Ghaffar, K. Usman
OBJECTIVE: To determine the frequency of hyperuricemia in type 2 diabetes mellitus (T2DM) patients with BMI >23 kg/m2MATERIALS AND METHODS: This descriptive study was conducted from February 2020 to September 2021. All patients with Type 2 Diabetes Mellitus (T2DM )with body mass index (BMI) >23 kg/m2 were assessed for hyperuricemia through Roche Cobas 6000 series C501 in MTI Hayatabad Medical Complex’s laboratory.     RESULTS: Total number of patients was 300, out of which 60 % were males. The studied population has a mean age of 59 (SD =±7) years, mean systolic blood pressure was 151 (SD = ±17) mmHg, mean duration of T2DM was 13 (SD = ±4) years, mean HbA1c was 10.9 (SD = ±2.5) %, mean BMI was 28.8 (SD = ±3.1) kg/m2 and mean serum uric acid was 5.7 (SD=±1.3) mg/dl. The overall prevalence of Hyperuricemia was 47% (36.7 % males and 62.5% females). Of those with hyperuricemia, 73 % were also found to have hypertension. Results showed that patients with hyperuricemia belonged to older age, and have higher Systolic blood pressure, raised BMI, and HbA1c. The mean differences were considered statistically significant with a p-value < 0.05 by using an independent sample t-test.CONCLUSION: The current study demonstrated a higher prevalence of hyperuricemia in T2DM patients with BMI> 23 kg/m2. Patients with hyperuricemia had a higher mean HbA1c, higher mean BMI, and raised systolic component of blood pressure.KEY WORDS: BMI, Hyperuricemia, Hypertension, Type 2 diabetes mellitus, HbA1c
目的:确定BMI为bb0 23 kg/m2的2型糖尿病(T2DM)患者高尿酸血症的发生率。材料和方法:本描述性研究于2020年2月至2021年9月进行。在MTI Hayatabad医疗综合医院的实验室,通过罗氏Cobas 6000系列C501对所有体重指数(BMI)为> - 23 kg/m2的2型糖尿病(T2DM)患者进行高尿酸血症评估。结果:患者总数300例,其中男性占60%。研究人群的平均年龄为59 (SD=±7)岁,平均收缩压为151 (SD=±17)mmHg,平均T2DM病程为13 (SD=±4)年,平均HbA1c为10.9 (SD=±2.5)%,平均BMI为28.8 (SD=±3.1)kg/m2,平均血清尿酸为5.7 (SD=±1.3)mg/dl。高尿酸血症的总体患病率为47%(男性36.7%,女性62.5%)。在高尿酸血症患者中,73%的人同时患有高血压。结果显示,高尿酸血症患者年龄偏大,收缩压增高,BMI升高,HbA1c升高。采用独立样本t检验,p值< 0.05,认为平均差异有统计学意义。结论:目前的研究表明,高尿酸血症在BMI为bbb23 kg/m2的T2DM患者中患病率更高。高尿酸血症患者平均HbA1c较高,平均BMI较高,收缩压升高。关键词:BMI,高尿酸血症,高血压,2型糖尿病,HbA1c
{"title":"FREQUENCY OF HYPERURICEMIA IN TYPE 2 DIABETES MELLITUS PATIENTS WITH BMI >23 KG/M2- STUDY AT A TERTIARY CARE HOSPITAL","authors":"Aqil Noor, Shaista Kanwal, Suleman Elahi Malik, Zafran Ullah, T. Ghaffar, K. Usman","doi":"10.52764/jms.23.31.2.4","DOIUrl":"https://doi.org/10.52764/jms.23.31.2.4","url":null,"abstract":"OBJECTIVE: To determine the frequency of hyperuricemia in type 2 diabetes mellitus (T2DM) patients with BMI >23 kg/m2\u0000MATERIALS AND METHODS: This descriptive study was conducted from February 2020 to September 2021. All patients with Type 2 Diabetes Mellitus (T2DM )with body mass index (BMI) >23 kg/m2 were assessed for hyperuricemia through Roche Cobas 6000 series C501 in MTI Hayatabad Medical Complex’s laboratory.     \u0000RESULTS: Total number of patients was 300, out of which 60 % were males. The studied population has a mean age of 59 (SD =±7) years, mean systolic blood pressure was 151 (SD = ±17) mmHg, mean duration of T2DM was 13 (SD = ±4) years, mean HbA1c was 10.9 (SD = ±2.5) %, mean BMI was 28.8 (SD = ±3.1) kg/m2 and mean serum uric acid was 5.7 (SD=±1.3) mg/dl. The overall prevalence of Hyperuricemia was 47% (36.7 % males and 62.5% females). Of those with hyperuricemia, 73 % were also found to have hypertension. Results showed that patients with hyperuricemia belonged to older age, and have higher Systolic blood pressure, raised BMI, and HbA1c. The mean differences were considered statistically significant with a p-value < 0.05 by using an independent sample t-test.\u0000CONCLUSION: The current study demonstrated a higher prevalence of hyperuricemia in T2DM patients with BMI> 23 kg/m2. Patients with hyperuricemia had a higher mean HbA1c, higher mean BMI, and raised systolic component of blood pressure.\u0000KEY WORDS: BMI, Hyperuricemia, Hypertension, Type 2 diabetes mellitus, HbA1c","PeriodicalId":39900,"journal":{"name":"Journal of Medical Sciences (Taiwan)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48450391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A STUDY OF AUTHORITARIAN PARENTING STYLE AND AGGRESSION AMONG ADOLESCENTS 专制教养方式与青少年攻击性的研究
Q4 Medicine Pub Date : 2023-05-23 DOI: 10.52764/jms.23.31.2.8
Saima Arzeen, Naeema Arzeen, Syed mubashar Shah
Objective: To examine   the link of authoritarian parenting style and aggression among adolescents. Material and Methods: Data was collected from institutes (high school and intermediate colleges) located in Peshawar, Islamabad, and Rawalpindi. For the study, Parenting Authority Questionnaire (PAQ) and Buss and Perry Aggression Questionnaire (BPAQ) were used.  For current study the sample (N=200) of boys (n=98) and girls (n=102). Results: The study findings indicated that both variables (authoritarian parenting style and aggression) significantly correlated in desirable direction (r =.23**). However, results showed the non-significant gender differences on both variables of the study. Conclusion: Findings highlighted that dominating, harsh and controlling parenting style (authoritarian) stimulated aggressive acts or behavior in youth which promoted more extreme cases in Pakistani society.
目的:探讨权威型父母教养方式与青少年攻击行为的关系。资料和方法:数据收集于位于白沙瓦、伊斯兰堡和拉瓦尔品第的研究所(高中和中级学院)。本研究采用父母权威问卷(PAQ)和Buss & Perry攻击问卷(BPAQ)。对于目前的研究,样本(N=200)为男孩(N= 98)和女孩(N= 102)。结果:研究结果表明,专制教养方式和攻击性在理想方向上显著相关(r = 0.23 **)。然而,结果显示,在研究的两个变量上,性别差异不显著。结论:研究结果强调了支配、严厉和控制的父母方式(专制)刺激青少年的攻击行为或行为,从而促进了巴基斯坦社会中更多的极端案件。
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引用次数: 0
THE EFFICACY AND SAFETY OF MAGNESIUM SULPHATE FOR NEONATAL NEUROPROTECTION IN PATIENTS WITH IMMINENT PRETERM DELIVERIES: EXPERIENCE AT A TERTIARY CARE HOSPITAL 硫酸镁对即将早产患者新生儿神经保护的有效性和安全性:三级护理医院的经验
Q4 Medicine Pub Date : 2023-05-23 DOI: 10.52764/jms.23.31.2.10
Tayaba Mazhar, S. Rauf, Asma Ambareen, Shahnaz Nadir
ObjectiveThe study aimed to find the effect of 4 grams of intravenous bolus antenatal dose of magnesium Sulphate on maternal and neonatal outcomes in preterm births.Material and MethodsIn a one-year cross-sectional descriptive study,  patients with active preterm labor or those with planned preterm birth at 28-34 weeks of gestation were included. Antenatal magnesium Sulphate was administered as a 4gm IV loading dose over 30 minutes. The data was analyzed with SPSS (version 20), where mean ± standard deviation was used for numerical variables and frequency and percentages for categorical variables. The sample size was 88.  A P value <_0.05 is used as a threshold for statistical significance.ResultsThe mean age of patients was 28.78 (± SD of 6.038) and the mean period of gestation remained 32.04 (±1.868). Similarly, the mean cervical dilatation at which magnesium Sulphate was given was 6.591 (±1.358), the mean baby’s weight was 1.655 (±0.508) kg, and the mean Apgar score at 5 minutes was recorded as 7.11 (±1.208). Regarding the period of gestation of the patients, 15 (17.04%) were at 28-30 weeks, 26 (29.54%) were at 30– 32 weeks and 47 (53.4%) were at 32– 34 weeks. Out of 88 patients, normal vaginal deliveries were conducted in 61 (69.38%) whereas, 27 (30.68%) patients had cesarean sections.Neonatal seizures were observed in 3 (2.6%), intraventricular hemorrhage in 2 (1.754%), Periventricular leukomalacia (PVL) 1(0.877%), and neonatal mortality in 5 (4.38%).ConclusionMagnesium Sulphate is a safe drug that plays an important role in protecting immature brains. Four-gram bolus is a sufficient dose as compared with infusion, which requires additional human resources and risks attached to prolonged infusions.Key Words: Magnesium Sulphate, Preterm Deliveries, Neonatal Neuroprotection, Intraventricular Hemorrhage
目的本研究旨在探讨产前静脉滴注4克硫酸镁对早产产妇和新生儿结局的影响。材料和方法在一项为期一年的横断面描述性研究中,纳入了妊娠28-34周时有活动性早产或计划早产的患者。产前硫酸镁以4gm IV负荷剂量在30分钟内给药。使用SPSS(版本20)对数据进行分析,其中数值变量使用平均值±标准差,分类变量使用频率和百分比。样本量为88。P值<_0.05用作统计显著性的阈值。结果患者的平均年龄为28.78(±SD为6.038),平均妊娠期为32.04(±1.868)。同样,给予硫酸镁的平均宫颈扩张度为6.591(±1.358),婴儿的平均体重为1.655(±0.508)kg,5分钟时的平均Apgar评分为7.11(±1.208),15人(17.04%)在28-30周,26人(29.54%)在30-32周,47人(53.4%)在32-34周。在88名患者中,61名(69.38%)患者进行了正常阴道分娩,而27名(30.68%)患者进行剖宫产。新生儿癫痫发作3例(2.6%),脑室出血2例(1.754%),脑室周围白质软化症1例(0.877%),新生儿死亡率5例(4.38%)。与输注相比,4克的推注是足够的剂量,输注需要额外的人力资源和长期输注的风险。关键词:硫酸镁、早产、新生儿神经保护、脑室出血
{"title":"THE EFFICACY AND SAFETY OF MAGNESIUM SULPHATE FOR NEONATAL NEUROPROTECTION IN PATIENTS WITH IMMINENT PRETERM DELIVERIES: EXPERIENCE AT A TERTIARY CARE HOSPITAL","authors":"Tayaba Mazhar, S. Rauf, Asma Ambareen, Shahnaz Nadir","doi":"10.52764/jms.23.31.2.10","DOIUrl":"https://doi.org/10.52764/jms.23.31.2.10","url":null,"abstract":"Objective\u0000The study aimed to find the effect of 4 grams of intravenous bolus antenatal dose of magnesium Sulphate on maternal and neonatal outcomes in preterm births.\u0000Material and Methods\u0000In a one-year cross-sectional descriptive study,  patients with active preterm labor or those with planned preterm birth at 28-34 weeks of gestation were included. Antenatal magnesium Sulphate was administered as a 4gm IV loading dose over 30 minutes. The data was analyzed with SPSS (version 20), where mean ± standard deviation was used for numerical variables and frequency and percentages for categorical variables. The sample size was 88.  A P value <_0.05 is used as a threshold for statistical significance.\u0000Results\u0000The mean age of patients was 28.78 (± SD of 6.038) and the mean period of gestation remained 32.04 (±1.868). Similarly, the mean cervical dilatation at which magnesium Sulphate was given was 6.591 (±1.358), the mean baby’s weight was 1.655 (±0.508) kg, and the mean Apgar score at 5 minutes was recorded as 7.11 (±1.208). Regarding the period of gestation of the patients, 15 (17.04%) were at 28-30 weeks, 26 (29.54%) were at 30– 32 weeks and 47 (53.4%) were at 32– 34 weeks. Out of 88 patients, normal vaginal deliveries were conducted in 61 (69.38%) whereas, 27 (30.68%) patients had cesarean sections.\u0000Neonatal seizures were observed in 3 (2.6%), intraventricular hemorrhage in 2 (1.754%), Periventricular leukomalacia (PVL) 1(0.877%), and neonatal mortality in 5 (4.38%).\u0000Conclusion\u0000Magnesium Sulphate is a safe drug that plays an important role in protecting immature brains. Four-gram bolus is a sufficient dose as compared with infusion, which requires additional human resources and risks attached to prolonged infusions.\u0000Key Words: Magnesium Sulphate, Preterm Deliveries, Neonatal Neuroprotection, Intraventricular Hemorrhage","PeriodicalId":39900,"journal":{"name":"Journal of Medical Sciences (Taiwan)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49086120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE DIAGNOSTIC UTILITY OF MEAN PLATELET VOLUME (MPV) IN PATIENTS WITH EARLY NEONATAL SEPSIS 平均血小板体积在早期新生儿败血症诊断中的应用
Q4 Medicine Pub Date : 2023-05-23 DOI: 10.52764/jms.23.31.2.2
M. Idrees, M. Rehman, Sabahat Amir, M. I. Khan, M. Waqas, I. Rahman
Objective:To determine the diagnostic utility of mean platelet volume in patients presenting with early neonatal sepsis.Materials and methods:This validation study was conducted in the Department of the Pediatrics ward, Khyber Teaching Hospital, Peshawar. After seeking parental consent, a brief history of Neonatal Sepsis and co-morbidities was obtained. The patient's clinical record was reviewed for the presence of any of the conditions indicated in the exclusion criteria for this study. A questionnaire about the patient’s demographics, disease duration, and treatment records was compiled. Samples were taken and examined of such newborns with consent from the patient's guardians (n=322). 4 ml venous blood was collected from each subject. 2 ml was used for blood culture, and 2 ml was used for Mean Platelet Volume estimation each at hours 0, 24, and 48. Data was collected and analyzed using the SPPS 24.Results:A total of 322 newborns (154 males, 168 females) were enrolled. The Sepsis group as diagnosed by blood culture, had 201 cases while the control group had 121 participants. There was a significant difference (p-value less than 0.05) between the two groups for Mean Platelet Volume. The values for sensitivity, specificity, and negative and positive predictive values as compared to blood culture as the gold standard were 77.58, 55.31, 50.00, and 81.08 percent, respectively.Conclusion:The mean platelet volume has high diagnostic utility in patients with neonatal sepsis. 
目的:探讨平均血小板体积对新生儿早期脓毒症的诊断价值。材料与方法:本验证性研究在白沙瓦开伯尔教学医院儿科病房进行。在征得父母同意后,获得了新生儿败血症和合并症的简史。检查患者的临床记录是否存在本研究排除标准中指出的任何情况。编制了一份关于患者人口统计、病程和治疗记录的问卷。在患者监护人同意的情况下,对这些新生儿进行了采样和检查(n=322)。每位受试者采集静脉血4 ml。2 ml用于血培养,2 ml用于0、24和48小时的平均血小板体积估计。使用SPPS 24收集和分析数据。结果:共纳入新生儿322例(男154例,女168例)。血培养诊断的败血症组有201例,对照组有121例。两组平均血小板体积比较差异有统计学意义(p值< 0.05)。与血培养作为金标准相比,敏感性、特异性和阴性、阳性预测值分别为77.58%、55.31%、50.00%和81.08%。结论:平均血小板体积对新生儿脓毒症有较高的诊断价值。
{"title":"THE DIAGNOSTIC UTILITY OF MEAN PLATELET VOLUME (MPV) IN PATIENTS WITH EARLY NEONATAL SEPSIS","authors":"M. Idrees, M. Rehman, Sabahat Amir, M. I. Khan, M. Waqas, I. Rahman","doi":"10.52764/jms.23.31.2.2","DOIUrl":"https://doi.org/10.52764/jms.23.31.2.2","url":null,"abstract":"Objective:\u0000To determine the diagnostic utility of mean platelet volume in patients presenting with early neonatal sepsis.\u0000Materials and methods:\u0000This validation study was conducted in the Department of the Pediatrics ward, Khyber Teaching Hospital, Peshawar. After seeking parental consent, a brief history of Neonatal Sepsis and co-morbidities was obtained. The patient's clinical record was reviewed for the presence of any of the conditions indicated in the exclusion criteria for this study. A questionnaire about the patient’s demographics, disease duration, and treatment records was compiled. Samples were taken and examined of such newborns with consent from the patient's guardians (n=322). 4 ml venous blood was collected from each subject. 2 ml was used for blood culture, and 2 ml was used for Mean Platelet Volume estimation each at hours 0, 24, and 48. Data was collected and analyzed using the SPPS 24.\u0000Results:\u0000A total of 322 newborns (154 males, 168 females) were enrolled. The Sepsis group as diagnosed by blood culture, had 201 cases while the control group had 121 participants. There was a significant difference (p-value less than 0.05) between the two groups for Mean Platelet Volume. The values for sensitivity, specificity, and negative and positive predictive values as compared to blood culture as the gold standard were 77.58, 55.31, 50.00, and 81.08 percent, respectively.\u0000Conclusion:\u0000The mean platelet volume has high diagnostic utility in patients with neonatal sepsis.\u0000 ","PeriodicalId":39900,"journal":{"name":"Journal of Medical Sciences (Taiwan)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45848230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HYPOMAGNESEMIA CAUSING VENTRICULAR TACHYCARDIA IN PATIENTS PRESENTING TO A CORONARY CARE UNIT 低镁血症导致冠心病患者室性心动过速
Q4 Medicine Pub Date : 2023-05-23 DOI: 10.52764/jms.23.31.2.5
Z. Khan, Rahim Dil Khan, Charagh Hussain, Tariq Nawaz, Yasir Hakeem, Hameed Ullah
OBJECTIVE: To determine the frequency of hypomagnesemia in patients with ventricular tachycardia.Materials and Methods: It is a descriptive Cross-Sectional study conducted in the Department of Cardiology, MTI-HMC, Peshawar from 20 Sept 2020 to 20 Mar 2021 after approval from the Institutional Ethical Committee. Patients were managed according to the guidelines and hospital protocol. After stabilization, the data was collected. Age, sex, address, patient’s history of diabetes, and hypertension were noted. Patients` serum was sent for serum electrolytes level and also serum magnesium level. Patients were labeled as hypomagnesemia and Hypokalemia as per operational definitions.RESULTS: The Mean and SDs for age were 57.52+9.155. The Mean and SDs for the serum level of potassium were 4.93+0.806. The Mean and SDs for the serum level of magnesium were 1.22+0.423. Thirty-four (18.4%) patients were recorded in the 35-50 years age group while 151 (81.6%) patients were recorded in the 51-72 years age group. 144 (77.8%) male patients and 41 (22.2%) female patients were recorded. Diabetes mellitus was present in 42 (22.7%). Hypertension was present in 37 (20.0%) patients. 9 (26.5%) patients had past five days’ history of diuretics usage. 18 (9.7%) patients were recorded with Hypokalemia. Ninety-eight (53.0%) patients were found to have hyperkalemia. A total of 185 patients admitted to the CCU of our hospital having ventricular tachycardia were included in this study, out of which 70 (37.8%) patients having ventricular tachycardia were recorded with hypomagnesemia. 19 (38.8%) patients with diuretics induced Ventricular Tachycardia had hypomagnesemia and while remaining 51 (37.5%) patients with ischemic Ventricular Tachycardia and VT-RVOT respectively were recorded with hypomagnesemia (P Value = 0.875)CONCLUSION: The data suggest that magnesium deficiency does occur in ventricular tachycardia with an increased incidence of cardiac arrhythmias.KEYWORDS:Cardiovascular Disease, Ventricular Tachycardia, Hypomagnesemia
目的:确定室性心动过速患者低镁血症的发生频率。材料和方法:这是一项描述性横断面研究,经机构伦理委员会批准,于2020年9月20日至2021年3月20日在白沙瓦MTI-HMC心内科进行。根据指南和医院方案对患者进行管理。稳定后,收集数据。记录患者的年龄、性别、住址、糖尿病和高血压病史。发送患者血清以测定血清电解质水平和血清镁水平。根据操作定义,患者被标记为低镁血症和低钾血症。结果:年龄的平均值和标准差为57.52±9.155。血清钾水平的平均值和标准差为4.93+0.806。血清镁水平的平均值和标准差为1.22+0.423。35-50岁年龄组中记录了34名(18.4%)患者,51-72岁年龄组记录了151名(81.6%)患者。男性患者144例(77.8%),女性患者41例(22.2%)。糖尿病42例(22.7%),高血压37例(20.0%)。9名(26.5%)患者有超过5天的利尿剂使用史。18例(9.7%)患者记录为低钾血症。98名(53.0%)患者被发现患有高钾血症。本研究共纳入我院CCU收治的185例室性心动过速患者,其中70例(37.8%)室性心动速患者记录为低镁血症。19例(38.8%)利尿剂引起的室性心动过速患者出现低镁血症,其余51例(37.5%)缺血性室性心动速和VT-RVOT患者分别记录为低镁血症(P值=0.875)。关键词:心血管疾病、室性心动过速、低镁血症
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Journal of Medical Sciences (Taiwan)
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