Pub Date : 2020-07-03DOI: 10.3329/bjog.v33i1.43545
N. Islam
Background: Ectopic pregnancy is a common clinical condition. Diagnosis and management of this condition is necessary in due to day practice. Methods: A cross sectional study on ectopic pregnancy was conducted in Sir Salimullah Medical College and Mitford Hospital (SSMC & MH) , Dhaka, with the objective to analyze the risk factors and assess the results of management with respect to maternal morbidity and mortality of ectopic pregnancy during the last two years. Result: Fifty patients were admitted with ectopic pregnancy from 1st January 2008 to 31st December 2010.Frequency of ectopic pregnancy were 1.5% of total 3252 pregnancies. Risk factors were found in 45% of cases. Surgical treatment were performed in total 43 patients. There was one heterotrophic pregnancy and one case of abdominal pregnancy. Four patients were given intramuscular Methotrexate and two un-ruptured ectopics resolved spontaneously after by expectant management. Conclusion: Conservative management was an option but surgical treatment was done more often because of late referrals. Screening of high risk cases, early diagnosis and early intervention would reduce the morbidity in ectopic pregnancies. Address of Correspondence: Dr. Nazia Islam, Specialist , Dept. of Mother and Child Care, BRB Hospitals Ltd, East Razabazar (Former Gastro Liver Hospital), Panthopath, Dhaka-1215 email-naziaislam1978@gmail.com, Mobile-01715437494. appendisectomy etc were looked for and recorded. For confirmation of the diagnosis serum 2 hCG, Transvaginal sonography (TVS) was done and culdocentesis was performed in necessary cases. Plan of management of patient with ectopic pregnancy was decided according to the condition of patient. Emergency operation were planned and performed accordingly.
{"title":"Diagnostic Clues and Management of ectopic Pregnancy in Sir Salimullah Medical College and Mitford Hospital, Dhaka","authors":"N. Islam","doi":"10.3329/bjog.v33i1.43545","DOIUrl":"https://doi.org/10.3329/bjog.v33i1.43545","url":null,"abstract":"Background: Ectopic pregnancy is a common clinical condition. Diagnosis and management of this condition is necessary in due to day practice. Methods: A cross sectional study on ectopic pregnancy was conducted in Sir Salimullah Medical College and Mitford Hospital (SSMC & MH) , Dhaka, with the objective to analyze the risk factors and assess the results of management with respect to maternal morbidity and mortality of ectopic pregnancy during the last two years. Result: Fifty patients were admitted with ectopic pregnancy from 1st January 2008 to 31st December 2010.Frequency of ectopic pregnancy were 1.5% of total 3252 pregnancies. Risk factors were found in 45% of cases. Surgical treatment were performed in total 43 patients. There was one heterotrophic pregnancy and one case of abdominal pregnancy. Four patients were given intramuscular Methotrexate and two un-ruptured ectopics resolved spontaneously after by expectant management. Conclusion: Conservative management was an option but surgical treatment was done more often because of late referrals. Screening of high risk cases, early diagnosis and early intervention would reduce the morbidity in ectopic pregnancies. Address of Correspondence: Dr. Nazia Islam, Specialist , Dept. of Mother and Child Care, BRB Hospitals Ltd, East Razabazar (Former Gastro Liver Hospital), Panthopath, Dhaka-1215 email-naziaislam1978@gmail.com, Mobile-01715437494. appendisectomy etc were looked for and recorded. For confirmation of the diagnosis serum 2 hCG, Transvaginal sonography (TVS) was done and culdocentesis was performed in necessary cases. Plan of management of patient with ectopic pregnancy was decided according to the condition of patient. Emergency operation were planned and performed accordingly.","PeriodicalId":39936,"journal":{"name":"Bangladesh Journal of Obstetrics and Gynecology","volume":"33 1","pages":"49-53"},"PeriodicalIF":0.0,"publicationDate":"2020-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42454946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-03DOI: 10.3329/bjog.v33i1.43541
Shabera Arzoo, Shereen Yousof, Jahanara Rahman, S. Chowdhury
Introduction: Injectable iron sucrose and oral ferrous sulfate both are used for the correction of anaemia in second and third trimester of pregnancy. But injectable iron is supposed to be more effective than oral iron, as it needs less time for correction of anaemia and efficacy is more. Oral iron is cost effective but more time consuming. The objective of the study was to compare the safety of intravenous iron sucrose complex in the treatment of iron deficiency anemia in third trimester of pregnancy. To compare the efficacy of intravenous iron with oral iron. Method: A randomised controlled trial was conducted in which pregnant women with iron deficiency were sequentially selected from the pregnant women attended antenatal clinic of OPD of Institute of Child and Maternal Health (ICMH) and assigned either to injectable or to oral ferrous sulfate by random number table. Each study patient was given the total calculated amount of injectable iron sucrose {Hb deficit (gm/l) × body weight (kg) × 0.24+ storage iron mg } in divided dose 200 mg in 200 ml normal saline intravenously over 1 hour every alternate day . Each patient of the control group was given ferrous sulfate 200mg orally three times a day for 4 weeks. Pregnant women follow up at 4 weeks and 8 weeks after get treatment by oral and injectable iron. During follow up monitored for adverse effects, clinical and laboratory response and haemoglobin percentage were observed. Result: There were 75 patients in injectable group and 75 patients in oral group. Injectable group achieved a significantly higher Hb level (11.49 ± 0.39) than oral group Hb level (10.39 ± 0.75) after 8 weeks of treatment. Injectable group showed no major side effects, only two patient had complains .One patient complain of epigastic pain and one patient complain of tachycardia while in oral group complain of nausea and vomiting, epigastic pain, constipation, allergic reaction was found in 42.0%, 39.3%,35.7% and 3.6% respectively. Conclusion: Iron sucrose complex appears to be a safe and effective in the treatment of iron deficiency anemia. Key word: Iron deficiency anemia in pregnancy, Injectable iron, oral iron. Bangladesh J Obstet Gynaecol, 2018; Vol. 33(1): 40-44
{"title":"Iron Deficiency Anemia in Pregnancy: Intravenous Iron Sucrose versus Oral Iron Sulfate","authors":"Shabera Arzoo, Shereen Yousof, Jahanara Rahman, S. Chowdhury","doi":"10.3329/bjog.v33i1.43541","DOIUrl":"https://doi.org/10.3329/bjog.v33i1.43541","url":null,"abstract":"Introduction: Injectable iron sucrose and oral ferrous sulfate both are used for the correction of anaemia in second and third trimester of pregnancy. But injectable iron is supposed to be more effective than oral iron, as it needs less time for correction of anaemia and efficacy is more. Oral iron is cost effective but more time consuming. The objective of the study was to compare the safety of intravenous iron sucrose complex in the treatment of iron deficiency anemia in third trimester of pregnancy. To compare the efficacy of intravenous iron with oral iron. Method: A randomised controlled trial was conducted in which pregnant women with iron deficiency were sequentially selected from the pregnant women attended antenatal clinic of OPD of Institute of Child and Maternal Health (ICMH) and assigned either to injectable or to oral ferrous sulfate by random number table. Each study patient was given the total calculated amount of injectable iron sucrose {Hb deficit (gm/l) × body weight (kg) × 0.24+ storage iron mg } in divided dose 200 mg in 200 ml normal saline intravenously over 1 hour every alternate day . Each patient of the control group was given ferrous sulfate 200mg orally three times a day for 4 weeks. Pregnant women follow up at 4 weeks and 8 weeks after get treatment by oral and injectable iron. During follow up monitored for adverse effects, clinical and laboratory response and haemoglobin percentage were observed. Result: There were 75 patients in injectable group and 75 patients in oral group. Injectable group achieved a significantly higher Hb level (11.49 ± 0.39) than oral group Hb level (10.39 ± 0.75) after 8 weeks of treatment. Injectable group showed no major side effects, only two patient had complains .One patient complain of epigastic pain and one patient complain of tachycardia while in oral group complain of nausea and vomiting, epigastic pain, constipation, allergic reaction was found in 42.0%, 39.3%,35.7% and 3.6% respectively. Conclusion: Iron sucrose complex appears to be a safe and effective in the treatment of iron deficiency anemia. Key word: Iron deficiency anemia in pregnancy, Injectable iron, oral iron. Bangladesh J Obstet Gynaecol, 2018; Vol. 33(1): 40-44","PeriodicalId":39936,"journal":{"name":"Bangladesh Journal of Obstetrics and Gynecology","volume":"33 1","pages":"40-44"},"PeriodicalIF":0.0,"publicationDate":"2020-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3329/bjog.v33i1.43541","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43228820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-03DOI: 10.3329/bjog.v33i1.43546
N. Naher, F. Begum, N. Hashem
Background: Urinary tract infection (UTI) is common during pregnancy and especially so in pregnant patients with diabetes mellitus. The emergence of drug resistance and particularly the extended spectrum Beta-lactamase production by Escherechia Coli and Methicillin resistance in staphylococci, limits the choice of anti-microbials. Method: A cross-sectional study was conducted on 50 pregnant women with sign and symptoms of UTI in the Department of Obstetrics and Gynaecology, BIRDEM general Hospital-2 from January to June 2017. The objectives of the study were to determine the presence and type of pathogens found in pregnant diabetic women presenting with features of urinary tract infection, and to analyze their antibiotic sensitivity pattern. Clean catch midstream urine samples were collected using standard procedure and culture and sensitivity was done following standard bacteriological method. Results: Mean age of the study subjects was 29.84±5.29 yrs; 48% were in third trimester of pregnancy; 52% had Gestational Diabetes Mellitus (GDM) and 48% had Diabetes Mellitus (DM). Out of fifty pregnant women, thirty eight (76.0%) study subjects had positive growth. Of them, Escherechia coli was found in 57.9% cases, Klebsiella in 21.1%, Staphylococcus aureus in 7.9%, Enterococcus and Pseudomonas aeruginosa each in 2.6% case. Amikacin was found to be sensitive to 100% cases of E. Coli, Klebsiella & Enterococcus but 100% resistant to Streptococcus. Conclusion: In this study, E. Coli was the most common organisms causing UTI, which is less susceptible to conventional oral antibiotics but more susceptible to amikacin. So carefull drug selection is required for successful outcome in UTI.
{"title":"Antibiotic Sensitivity in UTI among Diabetic Pregnant Women","authors":"N. Naher, F. Begum, N. Hashem","doi":"10.3329/bjog.v33i1.43546","DOIUrl":"https://doi.org/10.3329/bjog.v33i1.43546","url":null,"abstract":"Background: Urinary tract infection (UTI) is common during pregnancy and especially so in pregnant patients with diabetes mellitus. The emergence of drug resistance and particularly the extended spectrum Beta-lactamase production by Escherechia Coli and Methicillin resistance in staphylococci, limits the choice of anti-microbials. Method: A cross-sectional study was conducted on 50 pregnant women with sign and symptoms of UTI in the Department of Obstetrics and Gynaecology, BIRDEM general Hospital-2 from January to June 2017. The objectives of the study were to determine the presence and type of pathogens found in pregnant diabetic women presenting with features of urinary tract infection, and to analyze their antibiotic sensitivity pattern. Clean catch midstream urine samples were collected using standard procedure and culture and sensitivity was done following standard bacteriological method. Results: Mean age of the study subjects was 29.84±5.29 yrs; 48% were in third trimester of pregnancy; 52% had Gestational Diabetes Mellitus (GDM) and 48% had Diabetes Mellitus (DM). Out of fifty pregnant women, thirty eight (76.0%) study subjects had positive growth. Of them, Escherechia coli was found in 57.9% cases, Klebsiella in 21.1%, Staphylococcus aureus in 7.9%, Enterococcus and Pseudomonas aeruginosa each in 2.6% case. Amikacin was found to be sensitive to 100% cases of E. Coli, Klebsiella & Enterococcus but 100% resistant to Streptococcus. Conclusion: In this study, E. Coli was the most common organisms causing UTI, which is less susceptible to conventional oral antibiotics but more susceptible to amikacin. So carefull drug selection is required for successful outcome in UTI.","PeriodicalId":39936,"journal":{"name":"Bangladesh Journal of Obstetrics and Gynecology","volume":"33 1","pages":"54-58"},"PeriodicalIF":0.0,"publicationDate":"2020-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3329/bjog.v33i1.43546","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46305711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-03DOI: 10.3329/bjog.v33i1.43550
A. Nessa, S. B. Chowdhury, P. Fatima, M. Kamal, Mohammad Sharif, A. Azad
Background: Cervical cancer (CC) is the fourth most common cancer in women worldwide with an estimated 569,847 new cases and 311,365 deaths in the year 2018. In Bangladesh, the incidence of CC was 8068 and 5214 women died from CC in the year 2018.1CC constitutes about 12% of the female cancer in this country.1 Methods: The present situation of cervical cancer screening program is reviewed. Results: The Government of Bangladesh (GOB) adopted visual inspection of cervix with acetic acid (VIA) method for cervical cancer screening. The major strengths of VIA is its simplicity, low cost, potential for immediate linkage with investigations/treatment, feasible in low resource settings and the possibility of rapid training to the providers. The GOB has extended the program to all districts and selected upazilas.The screening programme has been implemented through capacity building of service providers of Medical College Hospitals (MCHs), District Hospitals (DHs), Mother and Child care Welfare Centers (MCWCs) and selected Upazila Health Compleses(UHCs) and several institutes.Service providersare performing VIA for the women of 30 years and above at about 417 VIA centres at primary, secondary and tertiary level health care facilities of 64 districts of Bangladesh. Screen positive cases are being referred to the colposcopy clinics of 14 government MCHs and BSMMU, where evaluation and management are carried out. From January 2005 to June 2017, 1647380VIA tests were performed at different facilities with 4.6%positivity.Among the VIA +ve women attending women at the colposcopy clinic of Bangabandhu Sheikh Mujib Medical University (BSMMU), 51% had precancerous or cancerous condition of the cervix, 3312 (14.10%) were treated by local excision, 2428 (10.30%)by local ablative method and1413 (6%) women with cervical cancer were referred to oncology. In Bangladesh, LEEPand thermal ablation has acquired acceptability as a commonly used treatment method for selected CIN and ‘see-and-treat’ approach for high grade diseases combining colposcopy and LEEP/ thermal ablation has been adopted since the year 2010 to improve compliance to treatment. Conclusion: Bangladesh has established VIA as screening test for prevention of cervical cancer in quiet a good number of facilities with wide coverage. But the program has to be expanded readily to prevent cancer and reduce sufferings & untimely death of women due to this devastating disease. Key word: Prevention of cancer cervix; prevention of cancer cervix in Bangladesh, VIA in Bangladesh. See & Treat of cervical cancer. Bangladesh J Obstet Gynaecol, 2018; Vol. 33(1): 63-73
{"title":"Cervical Cancer Screening Program in Bangladesh","authors":"A. Nessa, S. B. Chowdhury, P. Fatima, M. Kamal, Mohammad Sharif, A. Azad","doi":"10.3329/bjog.v33i1.43550","DOIUrl":"https://doi.org/10.3329/bjog.v33i1.43550","url":null,"abstract":"Background: Cervical cancer (CC) is the fourth most common cancer in women worldwide with an estimated 569,847 new cases and 311,365 deaths in the year 2018. In Bangladesh, the incidence of CC was 8068 and 5214 women died from CC in the year 2018.1CC constitutes about 12% of the female cancer in this country.1 Methods: The present situation of cervical cancer screening program is reviewed. Results: The Government of Bangladesh (GOB) adopted visual inspection of cervix with acetic acid (VIA) method for cervical cancer screening. The major strengths of VIA is its simplicity, low cost, potential for immediate linkage with investigations/treatment, feasible in low resource settings and the possibility of rapid training to the providers. The GOB has extended the program to all districts and selected upazilas.The screening programme has been implemented through capacity building of service providers of Medical College Hospitals (MCHs), District Hospitals (DHs), Mother and Child care Welfare Centers (MCWCs) and selected Upazila Health Compleses(UHCs) and several institutes.Service providersare performing VIA for the women of 30 years and above at about 417 VIA centres at primary, secondary and tertiary level health care facilities of 64 districts of Bangladesh. Screen positive cases are being referred to the colposcopy clinics of 14 government MCHs and BSMMU, where evaluation and management are carried out. From January 2005 to June 2017, 1647380VIA tests were performed at different facilities with 4.6%positivity.Among the VIA +ve women attending women at the colposcopy clinic of Bangabandhu Sheikh Mujib Medical University (BSMMU), 51% had precancerous or cancerous condition of the cervix, 3312 (14.10%) were treated by local excision, 2428 (10.30%)by local ablative method and1413 (6%) women with cervical cancer were referred to oncology. In Bangladesh, LEEPand thermal ablation has acquired acceptability as a commonly used treatment method for selected CIN and ‘see-and-treat’ approach for high grade diseases combining colposcopy and LEEP/ thermal ablation has been adopted since the year 2010 to improve compliance to treatment. Conclusion: Bangladesh has established VIA as screening test for prevention of cervical cancer in quiet a good number of facilities with wide coverage. But the program has to be expanded readily to prevent cancer and reduce sufferings & untimely death of women due to this devastating disease. Key word: Prevention of cancer cervix; prevention of cancer cervix in Bangladesh, VIA in Bangladesh. See & Treat of cervical cancer. Bangladesh J Obstet Gynaecol, 2018; Vol. 33(1): 63-73","PeriodicalId":39936,"journal":{"name":"Bangladesh Journal of Obstetrics and Gynecology","volume":"33 1","pages":"63-73"},"PeriodicalIF":0.0,"publicationDate":"2020-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48607327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-03DOI: 10.3329/bjog.v33i1.43553
R. Perveen, M. Asaduzzaman
Background: Cystic enlargement of ovaries may develop due a large number of causes and may need surgical intervention. Moreover, some ovarian cysts arise due to endocrine disorders & do not require surgery. We report an unusual case of massive enlargement of ovaries with multiple cysts in a girl with severe hypothyroidism. Morphologic features of cysts on ultrasonography and clinical features of hypothyroidism with elevated TSH level facilitates diagnosis of multiple ovarian cysts and hypothyroidism. Case presentation: A 23-year-old unmarried woman presented with abdominal enlargement, pain and moderate anemia. Abdominal ultra sonogram revealed huge enlargement of the ovaries with multiple large cysts. She was admitted in a hospital, treated with blood transfusion and laparotomy was decided. She was referred to us in a private clinic. On further evaluation , she had features of hypothyroidism with high TSH level and abdomino-pelvic ultrasound revealed enlarged ovaries with multiple large thin-walled cysts and mild ascitis. Conservative management with thyroxin replacement therapy was given and after 3 weeks of thyroxine (T4) therapy, follow-up abdominal ultrasound showed significant reduction in ovarian size. After 4 months of thyroxine therapy, ovarian size normalized, cysts disappeared completely and there was significant improvement of patient’s condition and she became euthyroid. Conclusion: This case report highlights the rare association between hypothyroidism and multicystic ovarian enlargement. It is necessary to keep in mind the possibility of hypothyroidism in the differential diagnosis of adult patients with ovarian enlargement and multiple cyst formation in order to prevent unnecessary ovarian surgery. Bangladesh J Obstet Gynaecol, 2018; Vol. 33(1): 78-81
{"title":"Massive Ovarian Enlargement with Multiple Cysts Mimicking Ovarian Neoplasm and Primary Hypothyroidism","authors":"R. Perveen, M. Asaduzzaman","doi":"10.3329/bjog.v33i1.43553","DOIUrl":"https://doi.org/10.3329/bjog.v33i1.43553","url":null,"abstract":"Background: Cystic enlargement of ovaries may develop due a large number of causes and may need surgical intervention. Moreover, some ovarian cysts arise due to endocrine disorders & do not require surgery. We report an unusual case of massive enlargement of ovaries with multiple cysts in a girl with severe hypothyroidism. Morphologic features of cysts on ultrasonography and clinical features of hypothyroidism with elevated TSH level facilitates diagnosis of multiple ovarian cysts and hypothyroidism. Case presentation: A 23-year-old unmarried woman presented with abdominal enlargement, pain and moderate anemia. Abdominal ultra sonogram revealed huge enlargement of the ovaries with multiple large cysts. She was admitted in a hospital, treated with blood transfusion and laparotomy was decided. She was referred to us in a private clinic. On further evaluation , she had features of hypothyroidism with high TSH level and abdomino-pelvic ultrasound revealed enlarged ovaries with multiple large thin-walled cysts and mild ascitis. Conservative management with thyroxin replacement therapy was given and after 3 weeks of thyroxine (T4) therapy, follow-up abdominal ultrasound showed significant reduction in ovarian size. After 4 months of thyroxine therapy, ovarian size normalized, cysts disappeared completely and there was significant improvement of patient’s condition and she became euthyroid. Conclusion: This case report highlights the rare association between hypothyroidism and multicystic ovarian enlargement. It is necessary to keep in mind the possibility of hypothyroidism in the differential diagnosis of adult patients with ovarian enlargement and multiple cyst formation in order to prevent unnecessary ovarian surgery. Bangladesh J Obstet Gynaecol, 2018; Vol. 33(1): 78-81","PeriodicalId":39936,"journal":{"name":"Bangladesh Journal of Obstetrics and Gynecology","volume":"33 1","pages":"78-81"},"PeriodicalIF":0.0,"publicationDate":"2020-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43944976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-20DOI: 10.3329/fmcj.v13i2.43649
Mst Moonmoon Begum, F. Sultana
Sertoli-Leydig Cell Tumor (SLCT) is an extremely rare and distinctive sex cord-stromal tumor. Ovarian sex cord-stromal tumors are infrequent tumors that differ from the more frequent epithelial neoplasm and have strong association with hormone-mediated syndromes, presentation in a wide age range, and the diagnosis is usually at early-stage disease with a good outcome. SLCT typically present with pelvic or abdominal pain and tenderness, mass, and or abnormal menstruation, and with hormonal activity reported predominantly after menarche. We report a case of 18-year-old unmarried female presented with severe pain and lump in the lower abdomen. She was a case of primary amenorrhea with normal secondary sex characters. She was a suspected case of twisted ovarian tumor on USG and underwent laparotomy followed by total excision of the lump and histopathology report revealed Sertoli-Leydig Cell Tumor. Though it is a rare tumor, the possibility of Sertoli-Leydig Cell Tumor in a young woman should be kept in mind. Key Words: Ovarian tumor, Sclerosing stromal tumor, sex cord-stromal tumor, Sertoli- Leydig Cell Tumor. Bangladesh J Obstet Gynaecol, 2017; Vol. 32(2) : 117-120
{"title":"Sertoli-Leydig Cell Tumor (SLCT) of the Ovary - A Case Report","authors":"Mst Moonmoon Begum, F. Sultana","doi":"10.3329/fmcj.v13i2.43649","DOIUrl":"https://doi.org/10.3329/fmcj.v13i2.43649","url":null,"abstract":"Sertoli-Leydig Cell Tumor (SLCT) is an extremely rare and distinctive sex cord-stromal tumor. Ovarian sex cord-stromal tumors are infrequent tumors that differ from the more frequent epithelial neoplasm and have strong association with hormone-mediated syndromes, presentation in a wide age range, and the diagnosis is usually at early-stage disease with a good outcome. SLCT typically present with pelvic or abdominal pain and tenderness, mass, and or abnormal menstruation, and with hormonal activity reported predominantly after menarche. We report a case of 18-year-old unmarried female presented with severe pain and lump in the lower abdomen. She was a case of primary amenorrhea with normal secondary sex characters. She was a suspected case of twisted ovarian tumor on USG and underwent laparotomy followed by total excision of the lump and histopathology report revealed Sertoli-Leydig Cell Tumor. Though it is a rare tumor, the possibility of Sertoli-Leydig Cell Tumor in a young woman should be kept in mind. Key Words: Ovarian tumor, Sclerosing stromal tumor, sex cord-stromal tumor, Sertoli- Leydig Cell Tumor. \u0000Bangladesh J Obstet Gynaecol, 2017; Vol. 32(2) : 117-120","PeriodicalId":39936,"journal":{"name":"Bangladesh Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46996302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-22DOI: 10.3329/bjog.v33i1.43267
M. Joarder, S. Begum, MS Ahmad, Md Immam Hossin, S. Islam, Md. Abdullah Yousuf Al Harun
Background: Cervical cancer remains a major public health problem worldwide – particularly in less developed countries. Around 85% of their new cases and 86% of deaths occur in less development countries (IARC, 2012). In Bangladesh, Cervical cancer is the second most common disease among female with an estimated 11,956 new cases and 6,582 deaths in 2012. Objectives: The present study was undertaken to identify the Effects of Human Papillomavirus infection with Pre-invasive cervical lesions in Bangladesh. Methods: This cross sectional study was carried out at the colposcopy clinic of Gynaecology and Obstetrics department of Bangabandhu Sheikh Mujib Medical University during the study period January 2015 - December 2015. A total of 65 consecutive women with VIA +ve cases of all three grades of CIN (CIN I, CIN II, CIN III) were enrolled in this study. Women having invasive cervical disease and women who not interested were excluded from this study. Results: More than one third (35.3%) patients were in 3rd decade. More than one third (35.4%) patients had normal colposcopic findings followed by 23(35.4%) was CIN I, 11(16.9%) was CIN II and 8(12.3%) was CIN III. Majority (42.6%) patients was found CIN I, 11(26.1%) was CIN II, 8(19.4%) was CIN III and 5(11.9%) had normal in Histopathology. CIN I histopathological finding was found 18 cases, among them 8(44.4%) in positive HC-2/Viral load/ RLU index. In multivariate analysis CIN III was significantly increased 1.34 times in HC-2/Viral load/RLU index positive (human Papillomavirus) cases (95% CI 0.22 – 8.9%, <0.05). Validity test of benign HPV DNA test of the study women showed that HPV DNA had sensitivity 51.4%, specificity 92.9%, accuracy 69.2%, positive predictive values 90.5% and negative predictive values 59.1%. Benign Colposcopic finding had had sensitivity 86.5%, specificity 64.3%, accuracy 76.9%, positive predictive values 76.2% and negative predictive values 78.3%. CIN III significantly 1.34 times increased HC-2/Viral load/ RLU index positive (human Papillomavirus) in multivariate analysis. Conclusion: From the findings of the study it was observed that colposcopy had a high sensitivity and optimum specificity; HPV DNA test had lower sensitivity and higher specificity. Colposcopic findings were closely associated with Histopathology, where the validity test was high when compared to HPV DNA test. So it can be concluded that the Colposcopy is a useful screening test for detection of cervical lesions and Human Papillomavirus is associated with pre-invasive cervical lessons. So the HPV DNA test can be used as a co-test with Colposcopy for screening of cervical lesions. Bangladesh J Obstet Gynaecol, 2018; Vol. 33(1) : 5-10
{"title":"Effects of Human Papillomavirus Infection with Pre-invasive Cervical Lesions: Bangladesh Perspectives","authors":"M. Joarder, S. Begum, MS Ahmad, Md Immam Hossin, S. Islam, Md. Abdullah Yousuf Al Harun","doi":"10.3329/bjog.v33i1.43267","DOIUrl":"https://doi.org/10.3329/bjog.v33i1.43267","url":null,"abstract":"Background: Cervical cancer remains a major public health problem worldwide – particularly in less developed countries. Around 85% of their new cases and 86% of deaths occur in less development countries (IARC, 2012). In Bangladesh, Cervical cancer is the second most common disease among female with an estimated 11,956 new cases and 6,582 deaths in 2012. Objectives: The present study was undertaken to identify the Effects of Human Papillomavirus infection with Pre-invasive cervical lesions in Bangladesh. \u0000Methods: This cross sectional study was carried out at the colposcopy clinic of Gynaecology and Obstetrics department of Bangabandhu Sheikh Mujib Medical University during the study period January 2015 - December 2015. A total of 65 consecutive women with VIA +ve cases of all three grades of CIN (CIN I, CIN II, CIN III) were enrolled in this study. Women having invasive cervical disease and women who not interested were excluded from this study. \u0000Results: More than one third (35.3%) patients were in 3rd decade. More than one third (35.4%) patients had normal colposcopic findings followed by 23(35.4%) was CIN I, 11(16.9%) was CIN II and 8(12.3%) was CIN III. Majority (42.6%) patients was found CIN I, 11(26.1%) was CIN II, 8(19.4%) was CIN III and 5(11.9%) had normal in Histopathology. CIN I histopathological finding was found 18 cases, among them 8(44.4%) in positive HC-2/Viral load/ RLU index. In multivariate analysis CIN III was significantly increased 1.34 times in HC-2/Viral load/RLU index positive (human Papillomavirus) cases (95% CI 0.22 – 8.9%, <0.05). Validity test of benign HPV DNA test of the study women showed that HPV DNA had sensitivity 51.4%, specificity 92.9%, accuracy 69.2%, positive predictive values 90.5% and negative predictive values 59.1%. Benign Colposcopic finding had had sensitivity 86.5%, specificity 64.3%, accuracy 76.9%, positive predictive values 76.2% and negative predictive values 78.3%. CIN III significantly 1.34 times increased HC-2/Viral load/ RLU index positive (human Papillomavirus) in multivariate analysis. \u0000Conclusion: From the findings of the study it was observed that colposcopy had a high sensitivity and optimum specificity; HPV DNA test had lower sensitivity and higher specificity. Colposcopic findings were closely associated with Histopathology, where the validity test was high when compared to HPV DNA test. So it can be concluded that the Colposcopy is a useful screening test for detection of cervical lesions and Human Papillomavirus is associated with pre-invasive cervical lessons. So the HPV DNA test can be used as a co-test with Colposcopy for screening of cervical lesions. \u0000Bangladesh J Obstet Gynaecol, 2018; Vol. 33(1) : 5-10","PeriodicalId":39936,"journal":{"name":"Bangladesh Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46617600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-22DOI: 10.3329/bjog.v33i1.43266
S. Khatun
Abstract not available Bangladesh J Obstet Gynaecol, 2018; Vol. 33(1) : 1-3
摘要不可用孟加拉国妇产科杂志，2018；第33卷（1）：1-3
{"title":"Prevention of Cervical Cancer","authors":"S. Khatun","doi":"10.3329/bjog.v33i1.43266","DOIUrl":"https://doi.org/10.3329/bjog.v33i1.43266","url":null,"abstract":"Abstract not available \u0000Bangladesh J Obstet Gynaecol, 2018; Vol. 33(1) : 1-3","PeriodicalId":39936,"journal":{"name":"Bangladesh Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44729215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Cervical cancer is 4th most common cancer in women in the world and the most common form of cancer in women in developing countries. Population based cervical cancer screening and treatment of intraepitheial neoplasia in early stage can reduce morbidity and mortality associated with cervical cancer. To determine the prevalence of cervical intra epithelial neoplasia (CIN) among sexually active and married women in Rajshahi Division of Bangladesh. Place and Duration: This population based cross sectional study was carried out in 4 selected Upazilla from 4 different districts of Rajshahi Division from 1st December 2014 to 31st May 2015. Study on 1050 sexually active women between 25 to 55 years of age who fulfilled the inclusion criteria enrolled in the study after taking the consent. Result: Among 1050 enrolled women 90 (8.5%) were VIA positive and 91 were colposcopically abnormal and among them 33 were CIN positive & 58 had chronic cervictis with or without squamorus metaplasia. Mean age of CIN positive women was 36.75 years, 92.2% were housewife & 7.8% were service holder and in 64.6% women education level was up to XII class. In fifty five percent of their husband was day labouer from poor socioeconomic condition. Conclusion: VIA and Colopscopy can differentiate a normal cervix from a precancerous cervix with reasonable accuracy. Till now a good number of studies had been carried out in different countries of world and it is now well established that sensitivity of the test is very good. From the present study we can conclude that it will give a very good information about the prevalence of CIN in our country and by proper management of the CIN cases the incidence of carcinoma cervix can be reduced. Bangladesh J Obstet Gynaecol, 2018; Vol. 33(1) : 17-20
{"title":"Prevalence of Cervical Intra Epithelial Neoplasia (CIN) among the sexually active married Women at Rajshahi Division","authors":"Jesmin Shahela, Najnin Monira, Ashrafunnesa, Afroz Romana, Sarkar Mousumi, S. Nargis","doi":"10.3329/bjog.v33i1.43269","DOIUrl":"https://doi.org/10.3329/bjog.v33i1.43269","url":null,"abstract":"Background: Cervical cancer is 4th most common cancer in women in the world and the most common form of cancer in women in developing countries. Population based cervical cancer screening and treatment of intraepitheial neoplasia in early stage can reduce morbidity and mortality associated with cervical cancer. To determine the prevalence of cervical intra epithelial neoplasia (CIN) among sexually active and married women in Rajshahi Division of Bangladesh. \u0000Place and Duration: This population based cross sectional study was carried out in 4 selected Upazilla from 4 different districts of Rajshahi Division from 1st December 2014 to 31st May 2015. Study on 1050 sexually active women between 25 to 55 years of age who fulfilled the inclusion criteria enrolled in the study after taking the consent. \u0000Result: Among 1050 enrolled women 90 (8.5%) were VIA positive and 91 were colposcopically abnormal and among them 33 were CIN positive & 58 had chronic cervictis with or without squamorus metaplasia. Mean age of CIN positive women was 36.75 years, 92.2% were housewife & 7.8% were service holder and in 64.6% women education level was up to XII class. In fifty five percent of their husband was day labouer from poor socioeconomic condition. \u0000Conclusion: VIA and Colopscopy can differentiate a normal cervix from a precancerous cervix with reasonable accuracy. Till now a good number of studies had been carried out in different countries of world and it is now well established that sensitivity of the test is very good. From the present study we can conclude that it will give a very good information about the prevalence of CIN in our country and by proper management of the CIN cases the incidence of carcinoma cervix can be reduced. \u0000Bangladesh J Obstet Gynaecol, 2018; Vol. 33(1) : 17-20","PeriodicalId":39936,"journal":{"name":"Bangladesh Journal of Obstetrics and Gynecology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41654881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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