Pub Date : 2022-03-12DOI: 10.31688/abmu.2022.57.1.12
A. Martiniuc, Ana Stănilă, D. Tabacelia, Radu Poenaru, Stefana Dumitras, Florina A. Nitu, R. Dumitru, M. Florescu, R. Grigorescu, C. Rosianu, L. Popa, Adelina Birceanu, D. Chiriţă, C. Stroescu
Introduction. The coronavirus disease 2019 (COVID-19) pandemic has constrained healthcare units to reorganize hospital departments, substantially reducing their capacity to perform oncology-related surgeries. Despite the efforts to reduce the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during hospitalization, COVID-19 has complicated the recovery of many surgical patients. Our objective was to assess the impact of SARS-CoV-2 infection on the postoperative evolution of patients with pancreatic surgery. Cases presentation. We present four patients with pancreaticoduodenectomy for malignant disease, operated in our hepato-biliary-pancreatic surgery department, who presented COVID-19 in the postoperative period, despite initial negative screening. 10% of patients who had pancreaticoduodenectomies were subsequently detected with minimal, moderate to severe forms of COVID-19 in the postoperative period, which led to an extension of the hospitalization period, in some cases, by up to five weeks. Conclusions. The side effects of COVID-19 pandemic are yet to have reached their limits. Pancreaticoduodenectomy is a complex surgery with high morbidity rates, but during the COVID-19 pandemics it has become more challenging.
{"title":"\"THE CLINICAL CONSEQUENCES OF SARS-CoV-2 INFECTION IN PATIENTS WITH PANCREATICODUODENECTOMY FOR MALIGNANT DISEASE\"","authors":"A. Martiniuc, Ana Stănilă, D. Tabacelia, Radu Poenaru, Stefana Dumitras, Florina A. Nitu, R. Dumitru, M. Florescu, R. Grigorescu, C. Rosianu, L. Popa, Adelina Birceanu, D. Chiriţă, C. Stroescu","doi":"10.31688/abmu.2022.57.1.12","DOIUrl":"https://doi.org/10.31688/abmu.2022.57.1.12","url":null,"abstract":"Introduction. The coronavirus disease 2019 (COVID-19) pandemic has constrained healthcare units to reorganize hospital departments, substantially reducing their capacity to perform oncology-related surgeries. Despite the efforts to reduce the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during hospitalization, COVID-19 has complicated the recovery of many surgical patients. Our objective was to assess the impact of SARS-CoV-2 infection on the postoperative evolution of patients with pancreatic surgery. Cases presentation. We present four patients with pancreaticoduodenectomy for malignant disease, operated in our hepato-biliary-pancreatic surgery department, who presented COVID-19 in the postoperative period, despite initial negative screening. 10% of patients who had pancreaticoduodenectomies were subsequently detected with minimal, moderate to severe forms of COVID-19 in the postoperative period, which led to an extension of the hospitalization period, in some cases, by up to five weeks. Conclusions. The side effects of COVID-19 pandemic are yet to have reached their limits. Pancreaticoduodenectomy is a complex surgery with high morbidity rates, but during the COVID-19 pandemics it has become more challenging.","PeriodicalId":40057,"journal":{"name":"Archives of the Balkan Medical Union","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43663762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-12DOI: 10.31688/abmu.2022.57.1.05
Mariia Y. Koteliukh
Introduction. Les complications tardives de l’infarctus du myocarde (IDM) constituent l’une des principales causes de ré hospitalisation et de mortalité parmi les patients avec diabète de type 2. L’objectif de l’étude était de prévoir le développement des complications tardives de l’IDM chez les patients avec diabète de type 2 ce qui a permis d’améliorer les méthodes diagnostiques chez cette cohorte de patients. Matériel et méthodes. Le total de 109 patients qui ont développé un diabète de type 2 après avoir subi un IDM, a été divisé en deux groupes : un groupe expérimental (n = 74) et un groupe témoin (n = 35). La détermination de l’adropine et C1q/Protéine 3 induite par le facteur de nécrose tumorale (CTRP3) a été réalisée au moyen de la méthode de dosage immuno-enzymatique. Le modèle de prédiction des complications tardives de l’IDM a été évalué en utilisant la régression logistique binaire. ABSTRACT
{"title":"\"A MODEL FOR PREDICTING LATE COMPLICATIONS OF MYOCARDIAL INFARCTION IN PATIENTS WITH TYPE 2 DIABETES MELLITUS\"","authors":"Mariia Y. Koteliukh","doi":"10.31688/abmu.2022.57.1.05","DOIUrl":"https://doi.org/10.31688/abmu.2022.57.1.05","url":null,"abstract":"Introduction. Les complications tardives de l’infarctus du myocarde (IDM) constituent l’une des principales causes de ré hospitalisation et de mortalité parmi les patients avec diabète de type 2. L’objectif de l’étude était de prévoir le développement des complications tardives de l’IDM chez les patients avec diabète de type 2 ce qui a permis d’améliorer les méthodes diagnostiques chez cette cohorte de patients. Matériel et méthodes. Le total de 109 patients qui ont développé un diabète de type 2 après avoir subi un IDM, a été divisé en deux groupes : un groupe expérimental (n = 74) et un groupe témoin (n = 35). La détermination de l’adropine et C1q/Protéine 3 induite par le facteur de nécrose tumorale (CTRP3) a été réalisée au moyen de la méthode de dosage immuno-enzymatique. Le modèle de prédiction des complications tardives de l’IDM a été évalué en utilisant la régression logistique binaire. ABSTRACT","PeriodicalId":40057,"journal":{"name":"Archives of the Balkan Medical Union","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44482996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-16DOI: 10.31688/abmu.2021.56.4.06
Trung Kien Nguyen, D. L. Nguyen, Thi Tuyet Ngan Doan, Hong Ha Nguyen, R. S. Dewey, V. D. Tran
Introduction. Les patients souffrant d’hypertension artérielle ont un taux plus élevé d’augmentation de la pression artérielle matinale (poussée matinale, PM) que les patients non hypertendus. La PM augmente le risque d’accident vasculaire cérébral, d’infarctus du myocarde, de mort subite d’origine cardiaque, de rigidité artérielle, d’hypertrophie ventriculaire gauche, d’athérosclérose carotidienne et d’inf lammation vasculaire. La prévalence et les prédicteurs de PM peuvent varier considérablement entre les régions géographiques. L’objectif de l’étude était de déterminer l’incidence de la PM et des facteurs associés chez les patients souffrant d’hypertension primaire. Matériel et méthodes. Une étude descriptive transversale a été menée chez des patients âgés de 35 ans et plus, diagnostiqués avec une hypertension artérielle primaire, et hospitalisés dans le service de cardiologie de l’hôpital de Thanh Vu, Bac Lieu, Vietnam, entre mars 2019 et mai 2020. ABSTRACT
导言。高血压患者的早晨血压升高率（晨吐，PM）高于非高血压患者。PM增加中风、心肌梗死、心脏猝死、动脉僵硬、左心室肥大、颈动脉动脉粥样硬化和血管缺血的风险。PM的患病率和预测因子在地理区域之间差异很大。本研究的目的是确定原发性高血压患者PM和相关因素的发病率。材料和方法。对2019年3月至2020年5月期间在越南Bac Liu Thanh Vu医院心脏科住院的35岁及以上诊断为原发性高血压的患者进行了横断面描述性研究。摘要
{"title":"Morning blood pressure surge and associated factors in patients with primary hypertension","authors":"Trung Kien Nguyen, D. L. Nguyen, Thi Tuyet Ngan Doan, Hong Ha Nguyen, R. S. Dewey, V. D. Tran","doi":"10.31688/abmu.2021.56.4.06","DOIUrl":"https://doi.org/10.31688/abmu.2021.56.4.06","url":null,"abstract":"Introduction. Les patients souffrant d’hypertension artérielle ont un taux plus élevé d’augmentation de la pression artérielle matinale (poussée matinale, PM) que les patients non hypertendus. La PM augmente le risque d’accident vasculaire cérébral, d’infarctus du myocarde, de mort subite d’origine cardiaque, de rigidité artérielle, d’hypertrophie ventriculaire gauche, d’athérosclérose carotidienne et d’inf lammation vasculaire. La prévalence et les prédicteurs de PM peuvent varier considérablement entre les régions géographiques. L’objectif de l’étude était de déterminer l’incidence de la PM et des facteurs associés chez les patients souffrant d’hypertension primaire. Matériel et méthodes. Une étude descriptive transversale a été menée chez des patients âgés de 35 ans et plus, diagnostiqués avec une hypertension artérielle primaire, et hospitalisés dans le service de cardiologie de l’hôpital de Thanh Vu, Bac Lieu, Vietnam, entre mars 2019 et mai 2020. ABSTRACT","PeriodicalId":40057,"journal":{"name":"Archives of the Balkan Medical Union","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45330668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-16DOI: 10.31688/abmu.2021.56.4.09
V. Musteata
Introduction. A growing number of studies indicates the increased susceptibility of patients with hematologic malignancies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection as compared to the apparently healthy population. The objective of our study was to identify and evaluate the contemporary epidemiological and diagnosis patterns of chronic myeloid leukemia (CML) in the context of coronavirus disease 2019 (COVID-19) pandemic, to optimize the management of this hematologic malignancy. Material and methods. This analytical, descriptive and prospective study included 15 patients with CML and COVID-19, who were treated and followed up in the Institute of Oncology Chisinau, Republic of Moldova, between 2005–2021. SARS-CoV-2 infection was diagnosed in these patients between April 2020–September 2021. Results. These 15 cases represented 10.6% out of 142 patients diagnosed with CML and followed up under the treatment with tyrosine kinase inhibitors. There were 9 (60.0%) males and 6 (40.0%) females, with the male/female ratio 1.5/1. The patients’ age at diagnosis of COVID-19 ranged between 38-74 years (average age 54.2 years). According to the World Health Organization classification of COVID-19 severity, mild forms were registered in 4 (26.7%) cases, moderate in 6 (40.0%) and severe in 5 (33.3%) cases. Eight (53.3%) patients were hospitalized for treatment of COVID-19: 5 patients with severe forms and 3 patients with moderate forms. Viral pneumonia was diagnosed in 6 patients: 5 with severe and one with moderate form of COVID-19. Non-infectious comorbidities were registered in 4 of 5 patients with severe COVID-19 forms. Conclusions. COVID-19 commonly affects CML patients of male gender and older than the average age of patients with CML. Patients without hematologic response presented an unfavorable evolution of both diseases, CML and COVID-19.
{"title":"COVID-19 in patients with chronic myeloid leukemia: management challenges and outcomes","authors":"V. Musteata","doi":"10.31688/abmu.2021.56.4.09","DOIUrl":"https://doi.org/10.31688/abmu.2021.56.4.09","url":null,"abstract":"Introduction. A growing number of studies indicates the increased susceptibility of patients with hematologic malignancies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection as compared to the apparently healthy population. The objective of our study was to identify and evaluate the contemporary epidemiological and diagnosis patterns of chronic myeloid leukemia (CML) in the context of coronavirus disease 2019 (COVID-19) pandemic, to optimize the management of this hematologic malignancy. Material and methods. This analytical, descriptive and prospective study included 15 patients with CML and COVID-19, who were treated and followed up in the Institute of Oncology Chisinau, Republic of Moldova, between 2005–2021. SARS-CoV-2 infection was diagnosed in these patients between April 2020–September 2021. Results. These 15 cases represented 10.6% out of 142 patients diagnosed with CML and followed up under the treatment with tyrosine kinase inhibitors. There were 9 (60.0%) males and 6 (40.0%) females, with the male/female ratio 1.5/1. The patients’ age at diagnosis of COVID-19 ranged between 38-74 years (average age 54.2 years). According to the World Health Organization classification of COVID-19 severity, mild forms were registered in 4 (26.7%) cases, moderate in 6 (40.0%) and severe in 5 (33.3%) cases. Eight (53.3%) patients were hospitalized for treatment of COVID-19: 5 patients with severe forms and 3 patients with moderate forms. Viral pneumonia was diagnosed in 6 patients: 5 with severe and one with moderate form of COVID-19. Non-infectious comorbidities were registered in 4 of 5 patients with severe COVID-19 forms. Conclusions. COVID-19 commonly affects CML patients of male gender and older than the average age of patients with CML. Patients without hematologic response presented an unfavorable evolution of both diseases, CML and COVID-19.","PeriodicalId":40057,"journal":{"name":"Archives of the Balkan Medical Union","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46831068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-16DOI: 10.31688/abmu.2021.56.4.14
Cuong Tran Chi, Phung NGUYEN KIM, Tuan Ngo Minh, D. T. Pham
supérieure et de ses branches devrait être soupçonné chez les patients avec de l’hémorragie gastro-intestinale inexpliquée. L’intervention endovasculaire est une approche faisable, surtout chez les patients aux multiples comorbidités et à risque élevé de saignement. Mots-clés: pseudo-anévrisme, artère mésentérique supérieure, artère iléale, thérapie endovasculaire, coil, saignement gastro-intestinal. upper and lower gastrointestinal endoscopy were in-conclusive. The diagnosis was confirmed by angiography and the patient was successfully treated by coil embolization. Conclusions. Ruptured pseudoaneurysm of superior mesenteric artery and its branches should be suspected in patients with unexplained gastrointestinal hemorrhage. Endovascular intervention is a feasible approach, especially in patients with multiple comorbidities and high bleeding risk.
{"title":"Ruptured ileal artery pseudoaneurysm: a rare cause of lower gastrointestinal hemorrhage","authors":"Cuong Tran Chi, Phung NGUYEN KIM, Tuan Ngo Minh, D. T. Pham","doi":"10.31688/abmu.2021.56.4.14","DOIUrl":"https://doi.org/10.31688/abmu.2021.56.4.14","url":null,"abstract":"supérieure et de ses branches devrait être soupçonné chez les patients avec de l’hémorragie gastro-intestinale inexpliquée. L’intervention endovasculaire est une approche faisable, surtout chez les patients aux multiples comorbidités et à risque élevé de saignement. Mots-clés: pseudo-anévrisme, artère mésentérique supérieure, artère iléale, thérapie endovasculaire, coil, saignement gastro-intestinal. upper and lower gastrointestinal endoscopy were in-conclusive. The diagnosis was confirmed by angiography and the patient was successfully treated by coil embolization. Conclusions. Ruptured pseudoaneurysm of superior mesenteric artery and its branches should be suspected in patients with unexplained gastrointestinal hemorrhage. Endovascular intervention is a feasible approach, especially in patients with multiple comorbidities and high bleeding risk.","PeriodicalId":40057,"journal":{"name":"Archives of the Balkan Medical Union","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46518474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-16DOI: 10.31688/abmu.2021.56.4.01
Veska T. Gergova, Asena Serbezova, D. Sidjimova
de cas de manière spécifique. Mots-clés: centré sur le patient, visite à domicile, es-sai clinique, pays européens. in Europe is often based on a case-by-case evaluation only. Notwithstanding the application of various national requirements and acts, they are either fragmen-tary, or not specifically applicable for such cases. and
De cas De maniires spiccifique。mots - cless: centr sur le patient, visite comdomicile, es-sai clinique, pays europsamens。在欧洲，通常只基于个案评估。尽管适用了各种国家规定和法令，但它们要么是零碎的，要么不是具体适用于这种情况。和
{"title":"Analysis on decentralized clinical trials in some European countries","authors":"Veska T. Gergova, Asena Serbezova, D. Sidjimova","doi":"10.31688/abmu.2021.56.4.01","DOIUrl":"https://doi.org/10.31688/abmu.2021.56.4.01","url":null,"abstract":"de cas de manière spécifique. Mots-clés: centré sur le patient, visite à domicile, es-sai clinique, pays européens. in Europe is often based on a case-by-case evaluation only. Notwithstanding the application of various national requirements and acts, they are either fragmen-tary, or not specifically applicable for such cases. and","PeriodicalId":40057,"journal":{"name":"Archives of the Balkan Medical Union","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48436853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-16DOI: 10.31688/abmu.2021.56.4.10
Raja Alkhasawneh, Kais Yazid Asad Ghanma, S. Aldaoud, Laith Siam Azzar Toeimeh, Ghaith Mshari ABU ALSAMEN, M. Obeidat, M. Shabaneh
Background. Hematologic markers ratios have been proposed as indicators to assist in the diagnosis and risk stratification of infectious diseases. The objective of the study was to explore the predictive value of neutrophils and monocytes to lymphocytes ratios (NLR and MLR, respectively) and to determine their cut-off values for the early severity stratification in mechanically ventilated critically ill SARS-CoV-2 infected patients. Material and methods. This study was retrospectively conducted on 193 patients admitted with COVID-19 in a specialized center in Jordan. Data were retrieved from the electronic medical record system over 9 months, between April – December 2020. Patients aged below 18 years, with a hospital length of stay less than 7 days, and whose studied variables were totally or partially missed were excluded from our study. An Independent and One-Sample T-Tests were used for parametric comparative data while non-parametric comparative variables were analysed using Chi Square Test. A receiver operating characteristic (ROC) was plotted to investigate the area under each curve (AUROC) of the tested prognosticator. Results. The mean age of the entire study group was 58.37±9.96 years, and the survivor group was insignificantly older than the non-survivor group (58.55±9.95 years versus 58.09±10.05 years, respectively). The 28-day intensive care unit mortality was detected in 94 patients (48.70%) during a mean of 12.40±4.79 days. NLR and MLR were significantly lower in the survivor group compared to the non-survivor cohort (2.22±0.99 and 0.25±0.10 versus 5.16±2.08 and 0.89±0.19, respectively, p <0.05). Conclusions. In this study, the higher values of MLR and NLR in patients with COVID-19, particularly in those with mechanical ventilation, could be used as predictors for risk stratification of patients with COVID-19.
{"title":"The predictive acccuracy for mortality of peripheral hematological markers ratios in mechanically ventilated COVID-19 patients","authors":"Raja Alkhasawneh, Kais Yazid Asad Ghanma, S. Aldaoud, Laith Siam Azzar Toeimeh, Ghaith Mshari ABU ALSAMEN, M. Obeidat, M. Shabaneh","doi":"10.31688/abmu.2021.56.4.10","DOIUrl":"https://doi.org/10.31688/abmu.2021.56.4.10","url":null,"abstract":"Background. Hematologic markers ratios have been proposed as indicators to assist in the diagnosis and risk stratification of infectious diseases. The objective of the study was to explore the predictive value of neutrophils and monocytes to lymphocytes ratios (NLR and MLR, respectively) and to determine their cut-off values for the early severity stratification in mechanically ventilated critically ill SARS-CoV-2 infected patients. Material and methods. This study was retrospectively conducted on 193 patients admitted with COVID-19 in a specialized center in Jordan. Data were retrieved from the electronic medical record system over 9 months, between April – December 2020. Patients aged below 18 years, with a hospital length of stay less than 7 days, and whose studied variables were totally or partially missed were excluded from our study. An Independent and One-Sample T-Tests were used for parametric comparative data while non-parametric comparative variables were analysed using Chi Square Test. A receiver operating characteristic (ROC) was plotted to investigate the area under each curve (AUROC) of the tested prognosticator. Results. The mean age of the entire study group was 58.37±9.96 years, and the survivor group was insignificantly older than the non-survivor group (58.55±9.95 years versus 58.09±10.05 years, respectively). The 28-day intensive care unit mortality was detected in 94 patients (48.70%) during a mean of 12.40±4.79 days. NLR and MLR were significantly lower in the survivor group compared to the non-survivor cohort (2.22±0.99 and 0.25±0.10 versus 5.16±2.08 and 0.89±0.19, respectively, p <0.05). Conclusions. In this study, the higher values of MLR and NLR in patients with COVID-19, particularly in those with mechanical ventilation, could be used as predictors for risk stratification of patients with COVID-19.","PeriodicalId":40057,"journal":{"name":"Archives of the Balkan Medical Union","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42011779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-16DOI: 10.31688/abmu.2021.56.4.04
R. A. Corb Aron, D. M. Ţiț, R. Moleriu, C. Vesa, Sergiu Bungau, A. G. Tarce, T. Behl, S. Bungău
Introduction. La composition du microbiote intestinal peut être affectée par le diabète de type 2 (T2DM) et le syndrome métabolique (SM), son amélioration est fréquemment ignorée dans les troubles métaboliques. L’objectif de l’étude était une évaluation comparative du microbiote fécal de témoins sains et de patients DT2 et SM (n = 150). Matériaux et méthodes. Une étude transversale rétrospective a été réalisée entre juillet 2019 et décembre 2020 dans le laboratoire Bio-standard Oradea, Roumanie. Un nombre de 75 patients atteints de DT2 non insulinodépendant et de SM (groupe d’étude = GE) et 75 sujets sains (groupe témoin = GT) ont été inclus dans l’étude. La composition du microbiome et l’influence du traitement antidiabétique oral sur le microbiome chez les patients SG ont été comparées. ABSTRACT
{"title":"Particularities of the intestinal microbiome composition in Romanian patients with metabolic syndrome and type 2 diabetes","authors":"R. A. Corb Aron, D. M. Ţiț, R. Moleriu, C. Vesa, Sergiu Bungau, A. G. Tarce, T. Behl, S. Bungău","doi":"10.31688/abmu.2021.56.4.04","DOIUrl":"https://doi.org/10.31688/abmu.2021.56.4.04","url":null,"abstract":"Introduction. La composition du microbiote intestinal peut être affectée par le diabète de type 2 (T2DM) et le syndrome métabolique (SM), son amélioration est fréquemment ignorée dans les troubles métaboliques. L’objectif de l’étude était une évaluation comparative du microbiote fécal de témoins sains et de patients DT2 et SM (n = 150). Matériaux et méthodes. Une étude transversale rétrospective a été réalisée entre juillet 2019 et décembre 2020 dans le laboratoire Bio-standard Oradea, Roumanie. Un nombre de 75 patients atteints de DT2 non insulinodépendant et de SM (groupe d’étude = GE) et 75 sujets sains (groupe témoin = GT) ont été inclus dans l’étude. La composition du microbiome et l’influence du traitement antidiabétique oral sur le microbiome chez les patients SG ont été comparées. ABSTRACT","PeriodicalId":40057,"journal":{"name":"Archives of the Balkan Medical Union","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43020466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-16DOI: 10.31688/abmu.2021.56.4.03
Kalbim Arslan, Feyzi Kurt
subi une appendicectomie. La durée moyenne du suivi était de 36,4 mois. Conclusions. Les pathologies des patients ayant subi une appendicectomie pour appendicite aiguë doivent être étroitement surveillées, les cas de tumeurs neuroendocrines doivent être réévalués et le traitement et le suivi de ces cas doivent être effectués en fonction des caractéristiques de la tumeur. Mots-clés: appendicite aiguë, tumeur neuroendocrine, tumeur carcinoïde, chirurgie, histopathologie. should be reevaluated, and treatment and follow-up of these cases should be done based on the tumour characteristics.
{"title":"Neuroendocrine tumours in patients operated for acute appendicitis: a retrospective clinical study","authors":"Kalbim Arslan, Feyzi Kurt","doi":"10.31688/abmu.2021.56.4.03","DOIUrl":"https://doi.org/10.31688/abmu.2021.56.4.03","url":null,"abstract":"subi une appendicectomie. La durée moyenne du suivi était de 36,4 mois. Conclusions. Les pathologies des patients ayant subi une appendicectomie pour appendicite aiguë doivent être étroitement surveillées, les cas de tumeurs neuroendocrines doivent être réévalués et le traitement et le suivi de ces cas doivent être effectués en fonction des caractéristiques de la tumeur. Mots-clés: appendicite aiguë, tumeur neuroendocrine, tumeur carcinoïde, chirurgie, histopathologie. should be reevaluated, and treatment and follow-up of these cases should be done based on the tumour characteristics.","PeriodicalId":40057,"journal":{"name":"Archives of the Balkan Medical Union","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42397541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-16DOI: 10.31688/abmu.2021.56.4.15
Ilir Gjermeni, E. Nelaj, Irida Kecaj, Eliona Gjermeni, M. Tase
{"title":"Nephrotoxicity by overdose of acetaminophen","authors":"Ilir Gjermeni, E. Nelaj, Irida Kecaj, Eliona Gjermeni, M. Tase","doi":"10.31688/abmu.2021.56.4.15","DOIUrl":"https://doi.org/10.31688/abmu.2021.56.4.15","url":null,"abstract":"","PeriodicalId":40057,"journal":{"name":"Archives of the Balkan Medical Union","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45623790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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