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Discrete Subaortic Stenosis in an Elderly Patient 离散性主动脉下狭窄的老年患者
Q4 Medicine Pub Date : 2021-06-01 DOI: 10.1177/26339447221098465
Jaideep Dey, Nadeem Akhtar, V. Shama, Arif Mustaqueem, S. Shrivastava
Discrete subaortic stenosis is an uncommon condition in the elderly population. Echocardiographic examination can be useful for diagnosis with high accuracy. We present a case report of an elderly female patient who presented with accelerated hypertension and was subsequently diagnosed with discrete subaortic stenosis on transthoracic echocardiography. A significant, non-dynamic, left ventricular outflow tract pressure gradient in the presence of aortic regurgitation should raise the possibility of this condition in patients of geriatric age group.
离散性主动脉下狭窄在老年人群中并不常见。超声心动图检查有助于诊断,准确率高。我们报告了一例老年女性患者,她表现为高血压加速,随后经胸超声心动图诊断为离散性主动脉下狭窄。存在主动脉反流的显著的、非动态的左心室流出道压力梯度应提高老年年龄组患者发生这种情况的可能性。
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引用次数: 0
Herpes Simplex Hepatitis Presenting as Fulminant Hepatic Failure in Pregnancy 单纯疱疹病毒性肝炎在妊娠期表现为暴发性肝衰竭
Q4 Medicine Pub Date : 2021-06-01 DOI: 10.1177/26339447221096200
K. Parvathy, A. Reghukumar, Athul Gurudas, K. Sasidharan, Lakshmi J. Nair
Herpes simplex hepatitis can progress to fulminant hepatic failure in immunocompromised patients as well as in pregnancy due to alterations in T cell-mediated immunity in these populations. If not identified early, herpes simplex virus (HSV) hepatitis will progress to fulminant hepatic failure requiring liver transplantation. Early identification and treatment with acyclovir can be life-saving as HSV hepatitis in pregnancy has been found to be associated with high mortality rate. We report the case of a 23-year-old woman who developed HSV-induced fulminant hepatic failure in the third trimester of pregnancy.
单纯疱疹病毒性肝炎可发展为暴发性肝功能衰竭在免疫功能低下的患者以及在怀孕由于改变在这些人群的T细胞介导的免疫。如果不及早发现,单纯疱疹病毒(HSV)肝炎将发展为暴发性肝衰竭,需要肝移植。早期发现和用阿昔洛韦治疗可以挽救生命,因为发现妊娠期HSV肝炎与高死亡率有关。我们报告的情况下,一个23岁的妇女谁发展单纯疱疹病毒引起的暴发性肝功能衰竭在妊娠晚期。
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引用次数: 1
Barriers and the Role of Assistive Technology to Access Education for Children with Visually Impaired During COVID-19 Times 2019冠状病毒病期间,辅助技术在视障儿童获得教育方面的障碍和作用
Q4 Medicine Pub Date : 2021-06-01 DOI: 10.1177/26339447221089124
Shweta Kapote, P. Srikanth
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引用次数: 3
The Hulk Hand!—In a Hemodialysis Patient 绿巨人之手!-一个血液透析病人
Q4 Medicine Pub Date : 2021-06-01 DOI: 10.1177/26339447221084415
M. Prabhakaran, H. Mahapatra, Amandeep Singh, Sanket Patil, Abhisek Gautam
A 35-year-old gentleman who was on maintenance hemodialysis for last 20 months presented with progressive swelling of the left upper limb. Initially, he had right nontunneled internal jugular vein (IJV) catheter followed by left nontunneled IJV catheter through which he received dialysis for 2 months. Further, his left brachiocephalic fistula (BCF) was created 18 months back. Since then, he was on regular thrice weekly dialysis through BCF. He started developing swelling of the left upper limb 8 months after fistula creation, which was gradually increasing. Blood flow was found to be normal during dialysis, examination suggestive of entire left upper limb swelling with thick induration. Doppler showed dilated outflow veins with high flow without any narrowing/stenosis of veins. Computed tomography venography done showed left brachiocephalic vein stenosis. He was found to have mega-fistula secondary to central vein stenosis which was managed successfully being discussed in this case report. Undiagnosed occult central venous stenosis in the prearteriovenous fistula (AVF) construction can manifest in various ways; one of them is as mega-fistula. It is the generalized aneurysmal dilatation of the entire outflow vessels of an AVF. Management option for this condition is limited depending on the etiology, fistula flow has to be reduced either by banding of the vessel or by fistula closure. Assessment of central veins before AVF construction and regular access surveillance in dialysis patients may prevent complications like these.
一位35岁的男士,进行维持性血液透析20个月后出现左上肢进行性肿胀。最初,他有右颈内静脉(IJV)导管,随后有左颈内静脉(IJV)导管,他接受了2个月的透析。此外,他的左头臂瘘(BCF)是在18个月前创建的。从那以后,他每周定期通过BCF进行三次透析。患者在造瘘8个月后开始出现左上肢肿胀,逐渐加重。透析时血流正常,检查提示整个左上肢肿胀伴厚硬结。多普勒显示流出静脉扩张,血流大,未见静脉狭窄。计算机断层扫描显示左头臂静脉狭窄。他被发现有继发于中央静脉狭窄的巨大瘘管,并成功地处理,并在本病例报告中讨论。在动静脉前瘘(AVF)构建中未确诊的隐匿性中心静脉狭窄可表现为多种方式;其中之一是巨瘘。它是AVF的整个流出血管的广泛性动脉瘤扩张。这种情况的治疗选择是有限的,取决于病因,瘘管流动必须通过血管绑扎或瘘管关闭来减少。透析患者在AVF构建前对中心静脉进行评估,并定期监测静脉通路,可预防此类并发症的发生。
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引用次数: 0
Case of an Exotic Skin and Soft Tissue Infection Associated with Cyclone Ockhi 与旋风奥基有关的外来皮肤和软组织感染病例
Q4 Medicine Pub Date : 2021-06-01 DOI: 10.1177/26339447211070986
Sreekumar Sivadasan, A. Reghukumar, Athul Gurudas, Kiran Kumar V. Sasidharan, S. Nair
Vibrio vulnificus is a halophilic marine gram-negative bacillus that is known to cause fulminant primary septicemia and complicated skin and soft tissue infections in humans. Vibrio vulnificus is referred to as flesh-eating bacteria. In the absence of timely detection and treatment, it results in sepsis with mortality of 50% and septic shock with mortality as high as 100%. Primary septicemia occurs following ingestion of contaminated seafood, and wound infections are acquired following exposure of open wounds to contaminated seawater. Early clinical suspicion and initiation of the appropriate antibiotics is essential to ensure good clinical outcome in case of Vibrio vulnificus septicemia. Here we report the case of a fisherman injured in cyclone Ockhi admitted to our hospital with lower limb cellulitis, who was diagnosed as Vibrio vulnificus wound infection. This case emphasizes the importance of history and clinical examination in antibiotic stewardship.
创伤弧菌是一种嗜盐的海洋革兰氏阴性杆菌,已知可引起人类暴发性原发性败血症和复杂的皮肤和软组织感染。创伤弧菌被称为食肉细菌。在没有及时发现和治疗的情况下,导致败血症死亡率高达50%,感染性休克死亡率高达100%。原发性败血症发生在摄入受污染的海产品后,伤口感染发生在开放性伤口暴露于受污染的海水后。在创伤弧菌败血症的情况下,早期临床怀疑和开始使用适当的抗生素对于确保良好的临床结果至关重要。在这里,我们报告的情况下,渔民受伤的旋风Ockhi入院的下肢蜂窝织炎,谁被诊断为创伤弧菌伤口感染。这个病例强调了病史和临床检查在抗生素管理中的重要性。
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引用次数: 0
Perceived Stress Levels and Associated Factors Among SARS-CoV-2-Affected Young Adults Under Home Isolation—A Cross-Sectional Study From Kerala, India 家庭隔离下受sars - cov -2影响的年轻人的感知压力水平及相关因素——来自印度喀拉拉邦的一项横断面研究
Q4 Medicine Pub Date : 2020-06-01 DOI: 10.1177/26339447211058643
Anjana Nalina Kumari Kesavan Nair, Jisharaj Vijayakumari Rajasekharan Nair, S. Swarnabai, R. Sudha, Alice Metilda Mendez, Leela Itty Amma
Introduction The impact of SARS-CoV-2 is not only on physical health but also on mental health. This pandemic raised concerns of fear, anxiety, and stress among patients affected with the disease. Quarantine and home isolation might have created psychological distress and helplessness in patients due to social and economic reasons. This study aimed in assessing the level of perceived stress and factors associated with it among SARS-CoV-2-affected young adults who were under home isolation. Methodology A cross-sectional study was conducted among 147 SARS-CoV-2-affected young adults who were under home isolation during June 2021 to August 2021. A semi-structured proforma was created using KoBo Toolbox for humanitarian response for data collection. Perceived Stress Scale (PSS-10) was used for measurement of stress among COVID-19 patients. The questionnaire was shared in online platform. Data was analyzed using Statistical Package for Social Sciences version 23.0. Significance of association was tested using chi square test and independent sample t test. Logistic regression was done to predict the factors associated with perceived stress. Results Out of the 147 study participants, 56.5% were females and 43.5% were males. Symptoms were present in 94 (63.9%) of patients. The mean age of the study participants was 26 (10.5) years. The mean PSS score was 17.5 (6.4). Among the cases under home isolation, 24.5% had low stress levels, 68% had moderate stress levels, and 7.5% had severe stress levels. Feeling of loneliness during home isolation (odds ratio [OR]: 4.7, 95% confidence interval [CI] [1.9-11.63], P = .008), presence of elderly or under-5 children in the same house (OR: 15.45, 95% CI [2.03-117.5], P = .001), and presence of cough (P = .05) were found to be significantly associated with higher PSS scores. Age and sleep were negatively correlated with stress score. Conclusion One-third of the study participants had moderate to severe levels of perceived stress. Age, sleep hours, presence of cough, presence of under-5 children or elderly in the same house, and feeling of loneliness during home isolation were found to be significantly associated with high perceived stress level scores.
SARS-CoV-2不仅对身体健康有影响,对心理健康也有影响。这次大流行引起了患者的恐惧、焦虑和压力。由于社会和经济原因,隔离和家庭隔离可能会造成患者的心理困扰和无助感。本研究旨在评估在家隔离的受sars - cov -2影响的年轻人的感知压力水平及其相关因素。方法对2021年6月至2021年8月期间居家隔离的147名感染sars - cov -2的年轻成年人进行横断面研究。使用KoBo工具箱创建了半结构化形式,用于人道主义响应数据收集。采用感知压力量表(PSS-10)测量新冠肺炎患者的压力水平。该问卷在网络平台上共享。数据分析使用Statistical Package for Social Sciences version 23.0。采用卡方检验和独立样本t检验检验相关性的显著性。采用Logistic回归预测与感知压力相关的因素。结果147名研究参与者中,56.5%为女性,43.5%为男性。94例(63.9%)患者出现症状。研究参与者的平均年龄为26岁(10.5岁)。PSS平均评分为17.5分(6.4分)。在居家隔离的病例中,24.5%为低压力水平,68%为中等压力水平,7.5%为严重压力水平。家庭隔离期间的孤独感(比值比[OR]: 4.7, 95%可信区间[CI] [1.9-11.63], P = 0.008)、家中有老人或5岁以下儿童(比值比[OR]: 15.45, 95% CI [2.03-117.5], P = 0.001)和咳嗽(P = 0.05)与较高的PSS评分显著相关。年龄、睡眠与压力得分呈负相关。三分之一的研究参与者有中度到重度的感知压力。年龄、睡眠时间、咳嗽、5岁以下儿童或老人住在同一所房子里,以及在家隔离期间的孤独感被发现与高感知压力水平得分显著相关。
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引用次数: 0
Weil’s Disease Death Investigation and Outbreak Control Measures Instituted in the Field Area of a Family Health Center in Thiruvananthapuram, Kerala—A Case Report 喀拉拉邦Thiruvananthapuram一家家庭保健中心野外地区Weil病死亡调查和疫情控制措施
Q4 Medicine Pub Date : 2020-06-01 DOI: 10.1177/26339447211067580
Pranav V. Vasisht
Introduction: Weil syndrome, a rare infectious disorder, is a severe form of the bacterial infection caused by Leptospira bacteria known as leptospirosis. Weil syndrome is characterized by dysfunction of the kidneys and liver, abnormal enlargement of the liver (hepatomegaly), persistent yellowing of the skin, mucous membranes, whites of the eyes (jaundice), and/or alterations in consciousness. In most cases, Weil syndrome occurs among individuals who are exposed to affected animals. Case Presentation and Summary: The investigation of death was done by a team consisting of doctor, junior health inspector, and ASHA workers of the area. We did a qualitative approach of in-depth interview of the wife and daughter-in-law of the deceased for data collection. The patient’s name and other details are not revealed for anonymity. No particular statistical analyses are used for this case reporting. The CARE guidelines were followed for writing this report. Conclusion: Leptospirosis is a disease of outbreak potential and has high case fatality rate. Timely identification of cases and institution of preventive measures is very important in preventing outbreaks. The surveys conducted in the area did not reveal any signs of an imminent or ongoing outbreak of leptospirosis.
简介:韦尔综合征是一种罕见的传染性疾病,是由钩端螺旋体引起的一种严重的细菌感染,称为钩端螺旋体病。Weil综合征的特征是肾脏和肝脏功能障碍,肝脏异常肿大(肝肿大),皮肤、粘膜、眼白(黄疸)持续变黄,和/或意识改变。在大多数情况下,威尔综合征发生在接触受感染动物的个体中。病例介绍和总结:死亡调查由一个由医生、初级卫生检查员和该地区ASHA工作人员组成的小组完成。我们对死者的妻子和儿媳进行了深度访谈的定性方法来收集数据。病人的姓名和其他细节因匿名而未透露。本病例报告没有使用特别的统计分析。撰写本报告时遵循了CARE指南。结论:钩端螺旋体病是一种具有暴发潜力的疾病,病死率高。及时发现病例和制定预防措施对预防疫情非常重要。在该地区进行的调查未发现任何即将或正在爆发钩端螺旋体病的迹象。
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引用次数: 0
Case of Mycotic Pseudoaneurysm of the Common Carotid Artery due to Salmonella typhi Bacteremia 伤寒沙门氏菌菌血症致颈总动脉真菌性假性动脉瘤1例
Q4 Medicine Pub Date : 2020-06-01 DOI: 10.1177/26339447211061041
S. Nair, A. Reghukumar, Athul Gurudas, K. Sasidharan, Sreekumar Sivadasan
Aneurysm of the extracranial carotid artery is a rare disease, mycotic pseudoaneurysms being even less common. They are a life-threatening complication of systemic infection and atherosclerosis. Immunocompromised people, including patients with HIV, uncontrolled diabetes melltus, those on immunosuppressants like high-dose steroids, and chemotherapy, are at a higher risk for development of mycotic pseudoaneurysms. Due to the high risk of potential complications like rupture and thromboembolic events, mycotic aneurysms always require surgical management. Early detection followed by restoration of blood flow is critical to minimize a fatal outcome. Here we report the case of a 52-year-old man with a past history of hypertension and dyslipidemia who presented with a pulsatile painful neck swelling. On evaluation, the patient was diagnosed to have Salmonella typhi bacteremia, HIV infection, and a mycotic aneurysm of the left common carotid artery.
颅外颈动脉动脉瘤是一种罕见的疾病,真菌性假性动脉瘤更不常见。它们是全身感染和动脉粥样硬化的危及生命的并发症。免疫功能低下的人,包括艾滋病患者、未控制的糖尿病患者、使用免疫抑制剂(如大剂量类固醇)和化疗的患者,患真菌性假性动脉瘤的风险更高。由于潜在并发症如破裂和血栓栓塞事件的高风险,真菌性动脉瘤总是需要手术治疗。早期发现并恢复血流对减少致命后果至关重要。在这里,我们报告的情况下,52岁的男子与高血压和血脂异常的过去的历史,谁提出了搏动疼痛颈部肿胀。经评估,患者被诊断为伤寒沙门氏菌菌血症、HIV感染和左侧颈总动脉真菌性动脉瘤。
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引用次数: 0
Evolution of Non-communicable Disease Programs in Kerala: Lessons Learnt and the Way Forward 喀拉拉邦非传染性疾病方案的演变:经验教训和前进方向
Q4 Medicine Pub Date : 2020-06-01 DOI: 10.1177/26339447211058621
J. Ramesh, R. Gaitonde
Addressing the double burden of disease in a country like India is a massive challenge, especially when the system is tuned to do monitoring and surveillance of mainly communicable diseases. Achieving the sustainable development goal target 3.4 to bring down the premature mortality from non-communicable diseases (NCDs) to one-third will need to consider the requirement of robust indicators at the national level to keep track of the prevalence of NCD and its risk factors among its population. The state of Kerala in contrast has a strong primary health care system that it can build on to address the rising NCD burden.
在印度这样的国家,解决疾病的双重负担是一项巨大的挑战,特别是当该系统主要用于监测和监测传染病时。实现可持续发展目标3.4将非传染性疾病造成的过早死亡率降至三分之一的具体目标,将需要考虑在国家一级制定强有力的指标的要求,以便跟踪非传染性疾病的流行情况及其在人口中的风险因素。相比之下,喀拉拉邦拥有强大的初级卫生保健系统,可以以此为基础解决日益增加的非传染性疾病负担。
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引用次数: 0
Celiac Disease Presenting as Hemolytic Anemia Mimic: A Case Report 腹腔疾病表现为溶血性贫血模拟:1例报告
Q4 Medicine Pub Date : 2020-06-01 DOI: 10.1177/26339447211053438
Anjum Siddiqui, R. Khan
Celiac disease, an immune-mediated enteropathy, results from gluten ingestion in the form of wheat, rye, and barley in genetically susceptible individuals. It is a systemic disorder characterized by a variable combination of gluten-related signs and symptoms, and disease-specific antibodies in addition to enteropathy. The clinical presentation of celiac disease is extremely variable: a small proportion of patients presenting with severe gastrointestinal symptoms and malabsorption, and extraintestinal symptoms, and a large proportion having no symptoms at all. Owing to the varied clinical presentation, diagnosing celiac disease remains a challenge. We present a case of celiac disease presenting with severe anemia and clinical features suggestive of hemolytic anemia, making diagnosis even more difficult.
乳糜泻是一种免疫介导的肠病,是由遗传易感个体摄入小麦、黑麦和大麦形式的麸质引起的。它是一种全身性疾病,其特征是谷蛋白相关体征和症状的可变组合,以及除肠病外的疾病特异性抗体。乳糜泻的临床表现千差万别:一小部分患者表现为严重的胃肠道症状和吸收不良,以及肠外症状,而很大一部分患者根本没有症状。由于各种临床表现,乳糜泻的诊断仍然是一个挑战。我们提出一个乳糜泻的病例,表现为严重的贫血和临床特征提示溶血性贫血,使诊断更加困难。
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引用次数: 0
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Journal, Indian Academy of Clinical Medicine
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