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Factors Related to Nutritional Status of Toddlers in the Working Area of Soropia Health Center, Konawe Regency in 2021 2021年科纳威县Soropia健康中心工作区域幼儿营养状况相关因素
Pub Date : 2022-11-08 DOI: 10.46496/medula.v10i1.28496
L. Lisnawaty, J. Jafriati, Nur-Kuain Hamka, Febriana Muchtar
ABSTRACTBackground: Nutritional status is a state of health related to the use of food by the body. As a result of poor nutritional status during infancy, it can cause stunted growth, cause toddlers to be lazy to carry out activities related to energy production, disruption of the toddler's immune system so that they  are  susceptible  to  infectious  diseases,  inhibition  of  optimal  brain  growth,  and  changes  in behavior such as apathy. Purposes: This study aimed to determine the relationship between parental income, and eating patterns in children under five with the occurrence of malnutrition in children under five in the working area of Soropia Health Center. Methods: This research was a quantitative research  that  is  observational  analytic  with  a  Cross  Sectional  Study  approach.  The  number  of samples were 50 toddler with a sampling technique using total sampling and for analysis using the Chi-Square test. Results: The results showed that there was a relationship between parental income (p=0.048) and eating patterns (p=0.000) with the nutritional status of children under five in the Soropia Health Center area in 2021. Conclusion:it was found that there was a relationship between parents' income and diet. on the nutritional status of children.Keywords: Toddler, nutritional status, parents' income, diet
摘要背景:营养状况是与机体对食物的利用有关的一种健康状态。由于婴儿期营养状况不佳,它会导致发育迟缓,导致幼儿懒得进行与能量产生有关的活动,破坏幼儿的免疫系统,使他们容易感染传染病,抑制最佳的大脑发育,以及行为改变,如冷漠。目的:本研究旨在确定父母收入、五岁以下儿童饮食模式与索洛比亚保健中心工作区域五岁以下儿童营养不良发生的关系。方法:本研究为定量研究,采用横断面研究方法进行观察分析。样本数量为50名幼儿,采用总抽样技术,采用卡方检验进行分析。结果:结果显示,父母收入(p=0.048)和饮食方式(p=0.000)与索罗亚保健中心区域2021年5岁以下儿童营养状况存在相关关系。结论:发现父母收入与饮食存在一定的关系。关于儿童营养状况。关键词:幼儿,营养状况,父母收入,饮食
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引用次数: 0
Hubungan Faktor Risiko dengan Kejadian Sindrom Dispepsia Fungsional pada Mahasiswa Fakultas Kedokteran Universitas Khairun 克伦大学医学院学生功能性消化不良综合征危险因素的关系
Pub Date : 2022-11-08 DOI: 10.46496/medula.v10i1.25877
Muhammad Sultan Firman Syah, A. Manaf, Fera The
Dispepsia merupakan kumpulan rasa tidak nyaman, nyeri epigastrium, kembung, mual muntah, sendawa dan rasa penuh. Stres, pola makan, makanan/minuman iritatif, obat anti inflamasi non-steroid (OAINS), Helicobacter pylori, alkohol dan merokok merupakan faktor risiko dispepsia. Meski berada di urutan ke-8 dari 10 penyakit spesifik di Maluku Utara, belum ada penelitian terkait hubungan faktor risiko dengan kejadian pada kelompok ini, khususnya pada kaum muda di Universitas Khairun. Tujuan: Mengetahui hubungan faktor risiko dengan kejadian sindrom dispepsia fungsional pada mahasiswa Fakultas Kedokteran Universitas Khairun. Metode: Penelitian observasional analitik cross sectional ini dilaksanakan mengunakan metode random sampling dari populasi mahasiswa Fakultas Kedokteran Universitas Khairun pada Januari 2022. Data diperoleh melalui kuesioner. Hasil: Dari 136 sampel, sebagian besar berusia 20-24 tahun (54,4%), 71,3% perempuan, 52,5% memiliki tingkat stres normal, 64,7% memiliki pola makan teratur, 56,6% mengonsumsi makanan/minuman iritatif, 23,5% mengonsumsi OAINS, 2,2% perokok, dan 6,6% mengonsumsi alkohol. Dispepsia fungsional dialami 55,9% mahasiswa. Dari seluruh variabel independen, jenis kelamin, tingkat stres, diet iritatif, OAINS, dan status perokok ditemukan berhubungan bermakna secara statistis dengan kejadian dispepsia fungsional (p<0,05). Simpulan: Pada mahasiswa Fakultas Kedokteran Universitas Khairun, jenis kelamin, tingkat stres, diet iritatif, OAINS, dan status perokok ditemukan berhubungan bermakna secara statistis dengan kejadian dispepsia fungsional.Kata Kunci: Dispepsia, faktor risiko, mahasiswa fakultas kedokteran
消化不良是一组不舒服的感觉,上腹疼痛、脚踝疼痛、恶心、呕吐、大笑和味觉饱胀。压力、饮食、刺激性食物/饮料、非甾体抗炎药、幽门螺杆菌、酒精和吸烟是消化不良的危险因素。尽管它在北马鲁古的10种特定疾病中排名第八,但没有研究与这一群体中事件相关的风险因素,尤其是在凯伦大学的年轻人中。目的:了解凯伦大学医学院学生发生功能性消化不良综合征的危险因素。方法:这项横断面观察性分析研究于2022年1月在凯伦大学医学院的学生群体中使用随机抽样方法进行。数据是通过内聚获得的。结果:在136个样本中,大多数是20-24岁(54.4%),71.3%是女性,52.5%有正常压力,64.7%有规律的饮食模式,56.6%吃刺激性食物/饮料,23.5%吃OAINS,2.2%吸烟,6.6%饮酒。55.9%的学生出现功能性消化不良。在所有自变量中,性别、压力水平、刺激性饮食、OAINS和吸烟状态与功能性消化不良的发生具有统计学相关性(p<0.05)。简介:在凯伦大学医学院的学生中,性别、压力水平、刺激性饮食、OAINS和吸烟状况被发现与功能性消化不良的发生具有统计学意义。关键词:消化不良,危险因素,医学生
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引用次数: 0
Risk Factors for Acute Respiratory Infection in Toddlers : A Case Control Study 幼儿急性呼吸道感染危险因素的病例对照研究
Pub Date : 2022-11-08 DOI: 10.46496/medula.v10i1.26409
Elpira Asmin, Mira Juanita, Vebiyanti Tentua
Background: Acute Respiratory Infection (ARI) is a disease that attacks the upper and lower respiratory tract caused by bacteria and viruses. ARI is one of the causes of high morbidity and mortality in under-fives. Purpose(s): This study aims to determine the relationship between toddler age, immunization status, smoking habits of family members, mother's knowledge, and residential density to the incidence of ARI in the working area of the Namlea Health Center in 2021 Methods: This study is a research study quantitative analysis using a case control research design. The sample in the case group was taken using the simple random sampling method and the control group was taken using the accidental sampling method. Results: the age of toddlers who were 36 months (55.2%), incomplete immunization status (46.9%), smoking habits of family members (68.8%), low maternal knowledge (30.2%), and density of bedroom occupancy (60.4%). The results of the chi-square test showed that the p-values for each variable were age (p = 0.035), immunization status (p = 0.017), room occupancy density (p = 0.022), mother's knowledge (p = 0.046), and smoking habits. family members (p = 0.036). Conclusion: There is a significant relationship between age, immunization status, room occupancy density, mother's knowledge, and smoking habits of family members with the incidence of ARI in children under five in the working area of the Namlea Health Center in 2021.
背景:急性呼吸道感染(ARI)是一种由细菌和病毒引起的侵袭上呼吸道和下呼吸道的疾病。ARI是五岁以下儿童发病率和死亡率高的原因之一。目的:本研究旨在确定2021年Namlea健康中心工作区幼儿年龄、免疫状况、家庭成员吸烟习惯、母亲知识和居住密度与ARI发病率之间的关系。方法:本研究是一项采用病例对照研究设计的研究性定量分析。病例组采用简单随机抽样法,对照组采用意外抽样法。结果:36个月幼儿的年龄(55.2%)、未完全免疫状态(46.9%)、家庭成员吸烟习惯(68.8%)、母亲知识水平低(30.2%)和卧室占用密度(60.4%)。卡方检验结果显示,每个变量的p值分别为年龄(p=0.035)、免疫状态(p=0.017)、房间占用密度(p=0.022),母亲的知识(p=0.046)和吸烟习惯。结论:2021年Namlea卫生中心工作区5岁以下儿童ARI发病率与家庭成员年龄、免疫接种状况、房间占用密度、母亲知识、吸烟习惯存在显著关系。
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引用次数: 0
Relationship between Waist Circumference (Abdomen) and Triglyceride and Low Density Lipoprotein-Cholesterol (LDL-C) Levels in Premenopausal Women 绝经前妇女腰围(腹部)与甘油三酯和低密度脂蛋白-胆固醇(LDL-C)水平的关系
Pub Date : 2022-11-08 DOI: 10.46496/medula.v10i1.26412
Mutmainnah Abbas, R. Mus
 Background: Premenopausal is a period that women will experience before heading to the menopause phase in the age range of 4 5-55 years. In the premenopausal period it is characterized by the instability of the hormone estrogen which will affect lipid metabolism which is closely related to the increase in abdominal fat known as abdominal or central obesity . The instability of the hormone estrogen results in hormonal changes that affect the levels of lipids in the body such as TG and LDL-Chol levels in the blood. Purpose(s): This study aims to determine whether there is a relationship between Waist Circumference (Abdomen) and Triglyceride and Low Density Lipoprotein-Cholesterol (LDL-C) Levels in Premenopausal Women. Methods: This study used an analytical correlative method with a cross-sectional study approach. This study involved 40 research subjects who met the criteria. Results: In the results of the pearson correlation test analysis to determine the relationship between the abdominal waist circle and TG levels in premenopausal women, the results of the p value = 0.351 and the pearson correlation test value = 0.15 were obtained. In the correlation test between waist circumference (abdomen) and LDL- Chol levels in premenopausal women, a value of p = 0.164 with a pearson correlation value of 0.224 was obtained. Conclusion: There is no relationship between Waist Circumference (Abdomen) and Triglyceride and Low Density Lipoprotein-Cholesterol (LDL-C) Levels in Premenopausal Women.Keywords: Premenopause, Waist Circumference, Lipid, Triglycerides, Low Density Lipoprotein
背景:绝经前是女性在进入绝经期前的一段时间,年龄范围为45 -55岁。绝经前的特点是雌激素不稳定这会影响脂质代谢这与腹部脂肪增加密切相关被称为腹部肥胖或中心性肥胖。雌激素的不稳定性导致激素变化,影响体内脂质水平,如血液中的TG和ldl -胆固醇水平。目的:本研究旨在确定绝经前妇女腰围(腹部)与甘油三酯和低密度脂蛋白-胆固醇(LDL-C)水平之间是否存在关系。方法:本研究采用相关分析方法和横断面研究方法。这项研究涉及40名符合标准的研究对象。结果:绝经前妇女腹腰圆与TG水平关系的pearson相关检验分析结果,p值= 0.351,pearson相关检验值= 0.15。绝经前妇女腰围(腹部)与LDL-胆固醇水平的相关性检验,p = 0.164, pearson相关值为0.224。结论:绝经前妇女腰围(腹部)与甘油三酯和低密度脂蛋白-胆固醇(LDL-C)水平无相关性。关键词:绝经前,腰围,脂质,甘油三酯,低密度脂蛋白
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引用次数: 0
The Activity of Notika Leaves (Archboldiodendron calosericeum KOBUSKI) Against Tumors Necrosis Factor Alpha (TNF-) Levels in Rats Notika叶对肿瘤坏死因子α(TNF)的活性-) 大鼠体内的水平
Pub Date : 2022-11-08 DOI: 10.46496/medula.v10i1.23816
N. Nuralifah, P. Parawansah, F. Malik, Nining Yulianti
Inflammation is a response process to tissue injury and infection. The inflammatory response causes the release of pro-inflammatory mediators such as IL-1, IL-6 and TNF-α which are the main cytokines in the acute inflammatory response. Plants that have the potential to be anti-inflammatory are notika leaves (Archboldiodendron calosericeum KOBUSKI). This research was conducted to determine the anti-inflammatory activity of the ethanol extract of notika leaves against the levels of Tumor Necrosis Factor Alpha (TNF-a) in wistar mice. This study used a post test only control group design. Using 5 treatment groups, namely positive control (diclofenac sodium), negative control (NaCMC 0.5%), 100 mg/kgBW extract test group, 200 mg/kgBW extract group and 300 mg/kgBW extract group. In vivo tests were carried out by induction of inflammatory substances, administering preparations and measuring TNF-α levels using the ELISA method. Data were analyzed using the One Way ANOVA test. The results showed that the mean levels of TNF-α in the positive control group (0.475 ng/L), negative control (0.816 ng/L), extract dose 100 mg/kgBW (0.67 ng/L), extract dose 200 mg/kgBW (0.7285 ng/L) and extract dosage of 300 mg/kgBW (0.7785 ng/L). The conclusion obtained is that the ethanol extract of notika leaves has anti-inflammatory activity against the levels of Tumor Necrosis Factor Alpha (TNF-a) in Wistar rats based on the reduction in levels with negative control and the best dose was 100 mg/kgBW.
炎症是对组织损伤和感染的反应过程。炎症反应引起促炎介质如IL-1、IL-6和TNF-α的释放,这些介质是急性炎症反应的主要细胞因子。具有潜在抗炎作用的植物是红叶(Archboldiodendron calosericeum KOBUSKI)。本研究旨在探讨香叶乙醇提取物对wistar小鼠肿瘤坏死因子α (TNF-a)的抗炎作用。本研究采用单纯后测对照组设计。采用5个治疗组,分别为阳性对照组(双氯芬酸钠)、阴性对照组(0.5% NaCMC)、100 mg/kgBW提取物试验组、200 mg/kgBW提取物组和300 mg/kgBW提取物组。体内试验通过诱导炎症物质、给药制剂和ELISA法测定TNF-α水平进行。数据分析采用单因素方差分析检验。结果表明:阳性对照组(0.475 ng/L)、阴性对照组(0.816 ng/L)、提取物剂量为100 mg/kgBW (0.67 ng/L)、提取物剂量为200 mg/kgBW (0.7285 ng/L)、提取物剂量为300 mg/kgBW (0.7785 ng/L)的小鼠血清TNF-α平均水平;结论:在阴性对照的基础上,红叶乙醇提取物对Wistar大鼠体内肿瘤坏死因子α (TNF-a)水平具有抗炎作用,最佳剂量为100 mg/kgBW。
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引用次数: 0
Aktivitas Antibakteri dan Skrining Fitokimia Ekstrak Etanol Daun Jambu Mete Anacardium occidentale L. Terhadap Pertumbuhan Escherichia coli Antibacterial Activity and Phytochemical Screening of Ethanol Extract of Cashew Leaves Anacardium occidentale L. Against Escherichia coli 腰果叶乙醇提取物对大肠杆菌的抗菌活性和植物化学筛选
Pub Date : 2022-11-08 DOI: 10.46496/medula.v10i1.26112
E. Astuty
ABSTRACTBackground: All parts of the cashew tree Anacardium occidentale L. (especially the leaves and bark) have been widely used as traditional herbal medicines, and are used throughout the world. Thus, in recent decades, the traditional medicinal properties of the Anacardium plant, and its various biological effects are being studied extensively. Purpose(s): This study aims to conduct a preliminary study of the antibacterial properties and phytochemical screening of the ethanol extract of cashew leaves. Methods: The antibacterial test of was determined by the Kirby baeur disc paper diffusion method. Qualitative test of phytochemical content was carried out using chemical reagents. Results: The results indicated that the ethanol extract of cashew leaves has an inhibitory effect on the growth of Escherichia coli. The smallest inhibition zone was found in the extract with a concentration of 10% of 5.75 mm and the largest was found at a concentration of 100% with a diameter of 14 mm. The phytochemical screening revealed that extracts contained; alkaloids, flavonoids, steroids, terpenoids, phenolics, saponins, and tanins Conclusion: The ethanol extract of cashew leaves was able to inhibit the growth of Escherichia coli test bacteria at all concentration variations. Phytochemical screening also found that the ethanol extract of cashew leaves contains alkaloids, flavonoids, steroid terpenoids, phenolics, saponins, and tannins which are known to have antibacterial properties.Keywords: cashew, ethanol extract, antibacteria ABSTRAKLatar Belakang: Semua bagian pohon jambu mete Anacardium occidentale L. (terutama daun dan kulit batang) telah banyak digunakan sebagai obat herbal tradisional, dan digunakan di seluruh dunia. Dengan demikian, dalam beberapa dekade terakhir, sifat obat tradisional tanaman Anacardium, dan berbagai efek biologis sedang dipelajari secara ekstensif Tujuan: Penelitian ini bertujuan untuk melakukan studi pendahuluan sifat antibakteri dan skrining fitokimia dari ekstrak etanol daun jambu mete. Metode: Uji antibakteri ekstrak ditentukan dengan metode difusi kertas cakram Kirby baeur. Uji kualitatif kandungan fitokimia dalam ekstrak dilakukan dengan pereaksi kimia. Hasil: Ekstrak etanol daun jambu mete memiliki daya hambat terhadap pertumbuhan Escherichia coli. Zona hambat terkecil terdapat pada ekstrak dengan konsentrasi 10% sebesar 5,75 mm dan terbesar terdapat pada konsentrasi 100% dengan diameter 14 mm. Hasil skrining fitokimia menunjukkan bahwa ekstrak etanol daun jambu mete mengandung senyawa golongan alkaloid, flavonoid, steroid, terpenoid, fenolik, saponin, dan tanin Simpulan: Ekstrak etanol daun jambu mete mampu menghambat pertumbuhan bakteri uji Escherichia coli pada semua variasi konsentrasi. Skrining fitokimia juga menemukan bahwa dalam ekstrak etanol daun jambu mete mengandung alkaloid, flavonoid, steroid terpenoid, fenolik, saponin, dan tannin yang diketahui memiki kemampuan sebagai antibakteriKata Kunci: jambu mete, ekstr
摘要背景:腰果的所有部位(尤其是叶和树皮)都被广泛用作传统中药材,并在世界各地广泛使用。因此,近几十年来,人们对Anacardium植物的传统药用特性及其各种生物学效应进行了广泛的研究。目的:本研究旨在对腰果叶乙醇提取物的抗菌性能和植物化学筛选进行初步研究。方法:采用Kirby-baeur纸片扩散法测定其抗菌活性。用化学试剂对植物化学成分进行了定性检测。结果:腰果叶乙醇提取物对大肠杆菌的生长有抑制作用。在浓度为10%的5.75mm提取物中发现最小的抑制区,在浓度为100%的直径为14mm的提取物中发现最大的抑制区。植物化学筛选显示提取物含有生物碱、黄酮类化合物、类固醇、萜类化合物、酚类化合物、皂苷类化合物和tanins类化合物结论:腰果叶乙醇提取物在各种浓度变化下都能抑制大肠杆菌试验菌的生长。植物化学筛选还发现,腰果叶的乙醇提取物含有生物碱、类黄酮、类固醇萜类、酚类、皂苷和单宁,这些物质已知具有抗菌特性。关键词:腰果、乙醇提取物、抗菌药[UNK]ABSTRAKLatar:西洋Anacardium occidentale L.的所有部位(尤其是叶和茎皮)都被广泛用作传统草药,并在世界范围内使用。因此,在过去的几十年里,人们对传统植物药Anacardium的性质及其各种生物学效应进行了广泛的研究。目的:本研究旨在对乙醇叶提取物进行抗菌前体研究和植物化学筛选。方法:采用Kirby-Baeur纸片扩散法测定提取物的抗菌性。提取物中植物化学成分的质量检测是通过化学作用进行的。结果:甲基蜡叶乙醇提取物对大肠杆菌生长有一定的抑制作用。最小的屏障区位于浓度为10%5.75mm的提取物上,最大的屏障区在直径为14mm的浓度为100%的提取物上。mete蠕虫的乙醇叶提取物可以在各种浓度下减缓大肠杆菌测试细菌的生长。植物化学筛选还发现,在乙醇提取物中,甲基炭疽叶中含有生物碱、类黄酮、萜类类固醇、酚类、皂苷和单宁,已知具有抗菌能力关键字:甲基炭疽,乙醇提取物,抗菌
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引用次数: 1
Correlation between Chest Radiograph and Lung Ultrasound with Clinical Appearance in Hyaline Membrane Disease Patients 透明质膜病患者胸部X线片和肺部超声与临床表现的相关性
Pub Date : 2022-11-08 DOI: 10.46496/medula.v10i1.28495
Wa Ode Zerbarani, Sri Asriani, Mirna Muis, Ema Alasir
ABSTRACT Background: Hyaline membrane disease (HMD) is a respiratory distress disease in premature infants due to surfactant deficiency. The combination of clinical, laboratory and radiological features makes it easy to quickly, precisely & accurately establish HMD which is important for early therapy in preventing death. Purpose: Knowing the suitability between chest X-ray & Thorax ultrasound with the clinical picture in HMD patients. Methods: This study is an observational study with a cross sectional method conducted in the radiology & NICU section of Dr. Wahidin Sudirohusodo Makassar from August 2021 to January  2022.  Sampling  was  done  by  consecutive  sampling.  The  researcher  performed  a  thorax ultrasound & assessed the chest x-ray. The results were verified by two pediatric radiology consultants. Results: The largest sample was in neonates at 34 weeks of gestation, 8 samples (21.1%), sex with 25 samples (65.8%), the highest birth weight between 1000-2000 grams 32 samples (84.2%) , the most preterm etiology was due to severe preeclampsia in 13 samples (34.2%), the most deliveries were by cesarean section 34 samples (89.4%), the highest APGAR Score was in moderate degree 25 samples (65.8%), the highest O2 saturation was between 90 -94%, namely 24 samples (63.2%), the most down scores were moderate degrees 15 samples (39.5%), HMD degrees based on chest radiographs were mostly grade II 25 samples (65.8%), HMD degrees based on thorax ultrasound the most in the moderate degree 19 samples (50%).Conclusion: Ultrasound is considered as the radiological modality of choice because it is safe, inexpensive, easy & sensitive to assess respiratory distress in neonates but is influenced by the operator's ability to apply it.Keywords: hyaline membrane disease, down score, chest radiograph, lung ultrasound
摘要背景:透明质膜病(HMD)是一种由表面活性剂缺乏引起的早产儿呼吸窘迫疾病。临床、实验室和放射学特征的结合使快速、准确和准确地建立HMD变得容易,这对预防死亡的早期治疗很重要。目的:了解胸部X光和胸部超声与HMD患者临床影像的适用性。方法:本研究是一项观察性研究,采用横断面方法,于2021年8月至2022年1月在Wahidin Sudirohusodo Makassar医生的放射学和新生儿重症监护室进行。通过连续采样进行采样。研究人员进行了胸部超声检查,并对胸部x光片进行了评估。两名儿科放射学顾问对结果进行了验证。结果:最大样本发生在妊娠34周的新生儿中,8个样本(21.1%),性别25个样本(65.8%),最高出生体重在1000-2000克之间32个样本(84.2%),最早产的病因是严重先兆子痫13个样本(34.2%),大多数产子是剖宫产34个样本(89.4%),O2饱和度最高在90-94%之间,即24个样本(63.2%),得分最高的是中等程度的15个样本(39.5%),基于胸部X光片的HMD程度大多是II级的25个样本(65.8%),基于胸部超声的HMD程度在中度19个样本中最多(50%)
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引用次数: 0
Antioxidant Potential of Organic Fraction of Turi Leaf Extract (Sesbania grandiflora L.) Using DPPH Reagent 大头草叶提取物有机组分的抗氧化活性研究使用DPPH试剂
Pub Date : 2022-05-25 DOI: 10.46496/medula.v9i2.25291
Wa Ode Sitti Musnina, Randa Wulaisfan, Jumriana Akhyar, Y. Yuyun
Background: White turi leaf (Sesbania grandiflora) is a plant from the Leguminosae family that isused as traditional medicine. Purpose(s): To determine the antioxidant potential of white turi leafextract (Sesbania grandiflora L) using DPPH reagent. Methods: White turi leaves (S. grandiflora)were extracted using maceration technique with ethanol the solvent. The ethanol extract wasfractionated using a liquid-liquid extraction using n-hexane, ethyl acetate, and ethanol. In addition,phytochemical screening was also carried out on secundary metabolite compounds contained in theethanol extract, it’s organic fractions. Results: Ethanol extract obtained as much as 160 g (16%).Fractionation of 10 grams of ethanol extract obtained n-hexane fraction 2.9 g (29%); ethyl acetatefraction 0.8 g (8%); and ethanol fraction 6.1 g (61%). Phytochemical screening showed that theethanol extract and ethyl acetate fraction contained flavonoids, saponins, and tannins; the ethanolfraction contains terpenoids, flavonoids, saponins, and tannins; while the n-hexane fraction containstannin compounds. The antioxidant activity of the ethanol extract, ethyl acetate fraction, and ethanolfraction were tested using the DPPH radical scavenging method. The antioxidant activity assayshowed that the SC50 values of the ethanol extract, ethyl acetate fraction, and ethanol fraction were234.7; 66,244, and 106.755 ppm, vitamin C as a positif control with SC50 3,006 ppm. Conclusion:white turi leaf extract (S. grandiflora) has antioxidant activity less than 22-78 times than controlpositif, so it is not potential as an antioxidant.  
背景:白turi叶(Sesbania grandflora)是豆科植物,被用作传统药物。目的:采用DPPH试剂测定大花叶提取物的抗氧化活性。方法:采用乙醇浸渍法提取桔梗白turi叶。用正己烷、乙酸乙酯和乙醇进行液-液萃取,对乙醇提取物进行分馏。此外,还对乙醇提取物及其有机组分中含有的次生代谢产物进行了植物化学筛选。结果:乙醇提取物可达160 g(16%)。10克乙醇提取物分馏得到正己烷馏分2.9克(29%);乙酸乙酯馏分0.8 g (8%);乙醇馏分6.1 g(61%)。植物化学筛选表明,乙醇提取物和乙酸乙酯部位含有黄酮类化合物、皂苷和单宁;乙醇馏分含有萜类、黄酮类、皂苷和单宁;而正己烷馏分则含有单宁化合物。采用DPPH自由基清除法对乙醇提取物、乙酸乙酯部分和乙醇部分的抗氧化活性进行了测试。抗氧化活性测定表明,乙醇提取物、乙酸乙酯部位和乙醇部位的SC50值均为234.7;66,244和106.755 ppm,维生素C作为阳性对照,SC50为3,006 ppm。结论:桔梗白turi叶提取物的抗氧化活性低于对照的22-78倍,不具有抗氧化潜力。
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引用次数: 0
Analysis of Leukocyte Count in Patients Acute Coronary Syndrome with ST-Segment Elevation and Acute Coronary Syndrome without ST-Segment Elevation at Kendari City General Hospital 肯达里市综合医院ST段抬高型急性冠状动脉综合征和无ST段抬高的急性冠状动脉综合症患者白细胞计数分析
Pub Date : 2022-05-25 DOI: 10.46496/medula.v9i2.25462
J. Jamaluddin, Irawaty Irawaty, Fercee Primula
Background: Acute coronary syndrome (ACS) is an acute complication of coronary heart disease due to rupture of an atherosclerotic plaque, resulting in the formation of a thrombus, narrowing the lumen, resulting in impaired blood supply and decreased strength of heart muscle contraction. The occurrence of inflammation in the atherosclerotic process is characterized by an increase in the number of leukocytes, which causes increased leukocyte recruitment at the site of plaque rupture and is thought to play an important role in the incidence and prognosis of ACS. Purpose: The aim of this study was to determine the comparison of the number of leukocytes in STE and NSTE ACS patients. Methods: This research was an observational analytic study. The research design used a cross sectional study carried out at the Kendari City Regional General Hospital with the independent variable STE and Non STE ACS and the dependent variable was the leukocytes count. The number of samples was 73 patients. Data were collected from medical record data in accordance with the inclusion criteria.  Bivariate analysis to compare the number of leukocytes using the unpaired T test. Results: Research from 73 respondents found that STE ACS patients had a mean leucocyte count of 10.31±3.50x103/μL while NSTE ACS patients had a mean leukocyte count of 8.62±3.43 x 103/μL (p=0,000). Conclusion: There was a significant difference of leukocyte count in STE ACS and NSTE ACS patients.
背景:急性冠状动脉综合征(Acute冠脉综合征,ACS)是一种由动脉粥样硬化斑块破裂引起的冠心病急性并发症,导致血栓形成,管腔变窄,导致血液供应受损和心肌收缩强度下降。动脉粥样硬化过程中炎症的发生以白细胞数量的增加为特征,白细胞数量的增加导致斑块破裂部位白细胞募集增加,被认为在ACS的发病率和预后中起重要作用。目的:本研究的目的是确定STE和NSTE ACS患者白细胞数量的比较。方法:本研究为观察性分析研究。研究设计采用在肯达里市地区总医院进行的横断面研究,自变量为STE和非STE ACS,因变量为白细胞计数。样本数量为73例。根据纳入标准从病历数据中收集数据。使用非配对T检验进行双变量分析以比较白细胞的数量。结果:对73例被调查者的研究发现,STE ACS患者的平均白细胞计数为10.31±3.50 × 103/μL,而NSTE ACS患者的平均白细胞计数为8.62±3.43 × 103/μL (p= 000)。结论:STE型ACS与NSTE型ACS患者白细胞计数有显著差异。
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引用次数: 0
The Relationship Between Nutritional Status with Post Dural Puncture Headache Incident in Sectio Caesarea Patients with Spinal Anesthesi 脊髓麻醉剖宫产术患者硬脊膜穿刺后头痛与营养状况的关系
Pub Date : 2022-05-25 DOI: 10.46496/medula.v9i2.25289
Agussalim Ali
Background: Post dural puncture headache (PDPH) is one of the most common complications of spinal anesthesia caused by leakage of cerebrospinal fluid (CSS) after anesthesia procedures. One of the factors that influence the incidence of PDPH is nutrional status where obese patients tend not to experience PDPH. This is based on an increase intraabdominal pressure in obese patients which can reduce CSF leakage in the epidural space. Purpose: Purpose of this study to determine whether there was a relationship between nutritional status and post dural puncture headache incident in sectio caesarea patients with spinal anesthesia at Aliyah 2 Hospital. Methods: This study used an observational analytic study with a cross sectional approach carried out at Aliyah 2 Hospital. The number of samples in this study was 51 people who were taken using total sampling technique. Data collection was obtained from medical records and filling out observation sheets for post-sectio caesarea patients with spinal anesthesia and then analyzed using the Fisher’s Exact Test. The dependent variable in this study was PDPH and the independent variables was the nutrional status. Result: This study showed that nutritional status (p = 0.007) had a significant relationship with the incidence of PDPH at Aliyah Hospital 2. Conclusion: From this study it could be concluded that the incidence of PDPH  after spinal anasthesia is higher in patients with low BMI. 
背景:硬脊膜穿刺后头痛(PDPH)是脊髓麻醉术后由脑脊液漏引起的最常见并发症之一。影响PDPH发病率的因素之一是营养状况,肥胖患者往往不会发生PDPH。这是基于肥胖患者增加腹内压可以减少脑脊液在硬膜外间隙的渗漏。目的:本研究旨在探讨阿利亚第二医院腰麻剖宫产术患者的营养状况与硬膜穿刺后头痛的关系。方法:本研究采用在Aliyah 2医院进行的横断面观察性分析研究。本研究的样本数量为51人,采用全抽样技术。对脊髓麻醉剖腹手术后剖腹手术患者的病历和观察表进行数据收集,并采用Fisher精确检验进行分析。本研究的因变量为PDPH,自变量为营养状况。结果:本研究显示,在Aliyah 2医院,营养状况与PDPH发病率有显著关系(p = 0.007)。结论:本研究表明,低BMI患者脊髓麻醉后PDPH发生率较高。
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引用次数: 0
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