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Effect of waveshape on iontophoretic drug delivery 波形对离子渗透给药的影响
C. Zakzewski, J.K. Li, D. Amory, E. Kalatzis-Manolakis
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引用次数: 1
A fractal approach to the problem of ventricular late potential detection 分形方法在心室晚期电位检测中的应用
O. Escalona
Detection of ventricular late potentials (VLP) following myocardial infarction (MI) can be a useful risk indicator. A reliable novel approach for detecting abnormal VLP activity based on fractal dimension analysis is presented. Computation of the fractal dimension (δ) of the VLP "attractor" traced in the microvoltage, 3-dimensional space, provided a reliable parameter for detecting abnormal VLP activity in post-MI patients. A clinical study suggested that a value of δ > 1.30 can be a risk criterion.
心肌梗死(MI)后心室晚期电位(VLP)的检测是一个有用的危险指标。提出了一种可靠的基于分形维数分析的VLP异常检测新方法。计算在微电压三维空间追踪的VLP“吸引子”的分形维数(δ),为检测心肌梗死后患者VLP异常活动提供了可靠的参数。一项临床研究表明,δ > 1.30可作为危险标准。
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引用次数: 1
Kardioassist - PC based system for modern ECG signal analysis. signal alignment method 基于PC的现代心电信号分析系统。信号对准法
J. Leski
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引用次数: 3
Symbolic motion analysis in digital subtraction angiography: a preliminary study 数字减影血管造影中的符号运动分析:初步研究
J. Puentes, C. Roux, M. Garreau, J. Coatrieux
displacements are quasi-homogeneous on a segment based analysis, a f i r s t approach to s tudy the twodimensional motions of the main coronary ar ter ies is propsed. A knowledge-based system extracts a n d interprets t h e d y n a m i c i n f o r m a t i o n . M o t i o n interpretations a r e obtained in two temporal image sequences a c q u i r e d in s t a n d a r d condi t ions, A prel iminary example of the system in te rpre ta t ion using declarative knowledge and d a t a representation is shown. T h e appl ica t ion of t h e homogeneous segment concept has permit ted to obtain a suitable arteries’ motion analysis. I . INTRODUCTION Visual interpretation includes perception, shape recognition, understanding, decision making and learning. Idcntification of useful entities in the image is one of the key problems to solve[l]. Interactions are simultaneous and varied, and a subjective inspection does not always differenciate between them. Knowledge based systems, aimed at the understanding of temporal image sequences, produce quantitative and qualitative evaluation of either objects or dynamic behaviors. Robot vision [ 2 ] and medical diagnosis (31, [4]. (51 are among the most important application fields. The objective in digital subtraction angiography is motivated by the need to work with qualitative, structural, morphological and kinetic properties. The analysis of cardiac movement is extremely complex. Normally, a highly qualified specialist is required to interpret these images. On the other hand, a great amount of the available angiography equipments take image sequences at one view angle and not at two angles simultaneously. Then, two dimensional motion analysis is rather used than three dimensional analysis. Most of the published works about the interpretation of cardiac angiographies are focused on the detection of lesions and do not include the temporal dimension. Usually, no more than two images are used. Studies are done with only two extreme positions of the heart, for example in ventricular analysis [6]. This work deals with knowledge based systems and image processing methods to analyse time-varying cardiovascular pictures. The temporal information given by the contrast medium circulation and the ECG signal is not considered in this work. Heart’s local and global behavior can be examined then, following only the coronary arteries’ displacements. This type of analysis relates three elements: artery’s position, magnitude and direction of its movement. The two-dimensional (2D) velocity vector associated to each artery’s point displacement is the basic data representation. The movement is qualitatively analysed in two temporal sequences recorded almost simultaneously with a biplane acquisition system R A 0 (right anterior oblique) and LAO (left anterior oblique) views. 11. METHOD OVERVIEW To achive qualitative kinetic description and motion analysis several steps must be accomplished: central line extraction, binary image representat
在基于段的分析中,位移是准均匀的,提出了一种研究主冠状动脉二维运动的方法。一种基于知识的系统,从数据中提取数据,并对数据进行解释。在两种时序图像序列中分别获得了两种不同的解译结果,并在两种不同的解译条件下,给出了该系统在使用陈述性知识和语义表示的情况下的一个初步示例。通过对均匀段概念的应用,可以得到合适的动脉运动分析。我。视觉解释包括感知、形状识别、理解、决策和学习。图像中有用实体的识别是需要解决的关键问题之一[1]。相互作用是同步的和多样的,主观的检查并不总是区分它们。基于知识的系统,旨在理解时间图像序列,产生对象或动态行为的定量和定性评估。机器人视觉[2]与医学诊断[31,[4]。(51)是最重要的应用领域。在数字减影血管造影术的目标是由需要工作与定性,结构,形态和动力学性质的动机。心脏运动的分析是极其复杂的。通常情况下,需要一个高素质的专家来解释这些图像。另一方面,现有的血管造影设备大多是在一个视角下拍摄图像序列,而不是在两个视角下同时拍摄。其次,采用二维运动分析而不是三维运动分析。大多数已发表的关于心脏血管造影解释的作品都集中在病变的检测上,而不包括时间维度。通常,使用的图像不超过两个。研究只在心脏的两个极端位置进行,例如在心室分析中[6]。这项工作涉及基于知识的系统和图像处理方法来分析时变心血管图像。在这项工作中没有考虑造影剂循环和心电信号所给出的时间信息。心脏的局部和全局行为可以在冠状动脉位移之后进行检查。这种类型的分析涉及三个要素:动脉的位置、大小和运动方向。与每个动脉的点位移相关的二维(2D)速度矢量是基本的数据表示。通过双平面采集系统ra0(右前斜)和LAO(左前斜)视图几乎同时记录两个时间序列,对运动进行定性分析。11. 为了实现定性的动力学描述和运动分析,必须完成几个步骤:中心线提取、二值图像表示和运动估计。它们是由171年已经报告的低水平处理进行的。利用动力学描述有效识别点的位置变化。假设物体的运动在基于片段的分析上是均匀的,就可以识别运动区域。这一概念指导目标识别任务产生有意义的不同图像描述之间的关系,创建来表示场景的动态演变。也就是说,必须有一组中间描述性元素,以便从计算值转换为符号。上下文层分为几个层次:(i)。速度矢量,动脉段的角方向,所选矢量场的平均角度和大小。(ii)运用先验知识来建立扩张、收缩的时间概念。全球运动方向、地方和全球趋势的不连续性。(iii).考虑到线性、离散和收敛的时间,设计了一个类似语言的时间尺度来识别心脏周期。每个容器都是二维中有序连接的点集。齐次线段被定义为一组相邻的点,它们的角取向,相对于相应的动脉线段,满足先前陈述的推断。在对两幅连续图像进行分析时,分配每个分支的运动解释标签。标签被添加到声明性知识库中。它们包括分支名称,视角,微分时间,间隔长度(如果是分支段)和确定的运动。为了减小知识库的大小,有必要确定哪些部分是相关的。所有段。小于预定义度量的,不包括在知识库中。这个启发式标准被用来过滤原始数据,我们仍然有相同的全局运动解释。标签是通过数据导向过程找到的。
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引用次数: 4
An optical device for interactive, image-guided neurosurgery 一种用于交互式、图像引导神经外科的光学装置
R. Galloway, R. Maciunas, W. Bass, D. Crouch
A device is presented which allows for the rapid display of surgical position and trajectory during neurosurgical procedures. The device’s position is determined by an optical triangulation device with an accuracy of approximately 0.1”. Surgical position is displayed on preoperatively obtained tomograms including Computed Tomography, Magnetic Resonance Imaging and Positron Emission Tomography scans.
提出了一种在神经外科手术过程中可以快速显示手术位置和轨迹的装置。该装置的位置由精度约为0.1“的光学三角测量装置确定。手术位置显示在术前获得的断层图像上,包括计算机断层扫描、磁共振成像和正电子发射断层扫描。
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引用次数: 10
Non-orthogonal Gabor representation of event-related potentials 事件相关电位的非正交Gabor表示
M. Brown, W. J. Williams, A. Hero
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引用次数: 7
Early embryonic development of xenopus laevis in 8 T and 40 nT magnetic fields 8t和40nt磁场对非洲爪蟾早期胚胎发育的影响
S. Ueno, M. lwasaka, K. Shiokawa
A possible influence of intense magnetic fields on the embryonic development of frogs was studied in reference to a potentiat hazardous problem in magnetic resonance imaging technology. We concluded that static magnetic fields up to 8 T do not appreciably affect the rapid cleavage and the following cell multiplication and differentiation in Xenopus laevis . We have also studied embryonic development of Xenopus laevis in 40 nT magnetic fields, and obtained similar results.
针对磁共振成像技术中存在的一个潜在危险问题,研究了强磁场对青蛙胚胎发育可能产生的影响。结果表明,8 T的静磁场对非洲爪蟾的快速分裂和随后的细胞增殖分化没有明显影响。我们也对非洲爪蟾在40nt磁场下的胚胎发育进行了研究,得到了类似的结果。
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引用次数: 2
Application of differential polarization light scattering to the study of bacterial cells 差偏振光散射在细菌细胞研究中的应用
A. Diaspro, M. Nizzari, M. Bertolotto, C. Nicolini
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引用次数: 0
New concepts in pacemaker technology 起搏器技术的新概念
Max Schaldach, A. Urbaszek, Helmut Hutten
Abstrod The aim of today’s pacemaker technology is to maintain a high quality of life and physical perfomace of the patient When natural sinus rhythm i s absent, a series of sensors with complex microelectronic contml circuits meets the need for rate-adaptive pacemaker systems while preserving AV synchrony. But only closed loop control has the potential to restore natural regulation. Intracardiac impedance measurements allow the monitoring of the contractile status of the heart, which depends mainly on the sympathetic drive. The ANS-contmlled pacemaker, which uses the stimulating electrode at the same time as the measuring electrode, is of special cIinical advantage The clinical evaluation of this pacing system in more than 200 patients confirmed adequate rate adaptation. Future developments are likely to make use of this possibility for eg arrhythmia prevention, intensive care monitoring o r as already implemented in conjunction with cardiomyoplasty.
当前的起搏器技术的目标是在没有自然窦性心律的情况下维持患者的高生活质量和身体机能,在保持房室同步的同时,一系列具有复杂微电子控制电路的传感器满足了心率自适应起搏器系统的需要。但只有闭环控制才有可能恢复自然调节。心内阻抗测量可以监测心脏的收缩状态,这主要取决于交感神经驱动。ans控制的起搏器,同时使用刺激电极和测量电极,具有特殊的临床优势。该起搏器在200多例患者的临床评估中证实了适当的心率适应。未来的发展可能会利用这种可能性,例如心律失常预防,重症监护监测或已经与心肌成形术一起实施。
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引用次数: 0
Achieving disabled access in the city of Oaxaca, Mexico 在墨西哥瓦哈卡市实现残疾人通道
R.E. Mayagoitia
On the initiative of the Mayor and with the advice of a biomedical engineer the City of Oaxaca began a project to make the center of the city accessible to the disabled, applying access standards previously developed in Mexico. The first stage has been finished, connecting the most important points in the center by wheelchair-accessible routes. There are people with disabilities the world over. However, it is uncommon to see them on the street or in public places in Mexico, where many physical (as well as social) barriers exist. There is v e q litZle legislation regarding access. Building codes are out of date in terms of %cess and urgently need to be revised. The regulations for Mexico City concentrate on human rights aspects and mention access in passing [l]. The= is state legislation in the State of Durango, where few specifics are given. The standard of the Ministry of Health is the only legislation applicable in the entire country and even though it is very specific it is only required of health care facilities [3]. Other national health care institutions, such as the Mexican Institute of Social Security, have their own standard. in accordance with but not identical to the Ministry of Health standard [41. In both cases access is obligatory only in new or hereafter remodeled health care facilities. Other entities offering disabled access do so out of good will and usually to their own intuitive standards. The health facility standards [3,4] were developed and revised by a multidisciplinary and multi-institutional team IS], where one of the members was a biomedical engineer. This person was asked by the Mayor of the City of Oaxaca to devise a project to make the center of the city accessible. Mexican standards were used.
在市长的倡议下,在一名生物医学工程师的建议下,瓦哈卡市启动了一个项目,采用墨西哥以前制定的通行标准,使市中心对残疾人无障碍。第一阶段已经完成,通过轮椅通道连接中心最重要的点。世界各地都有残疾人。然而,在墨西哥的街道或公共场所很少看到他们,那里存在许多物理(以及社会)障碍。关于获取信息的立法很少。建筑规范在进度方面已经过时,急需修订。墨西哥城的法规侧重于人权方面,并顺带提到了准入问题[1]。这是杜兰戈州的州立法,没有给出具体细节。卫生部的标准是唯一适用于全国的立法,尽管它非常具体,但它只适用于卫生保健设施[3]。其他国家卫生保健机构,如墨西哥社会安全研究所,也有自己的标准。符合但不完全等同于卫生部的标准[41]。在这两种情况下,只有在新的或以后改建的保健设施中,才能强制使用。其他提供残疾人通道的实体这样做是出于善意,通常是按照他们自己的直觉标准。卫生设施标准[3,4]是由一个多学科和多机构小组制定和修订的,其中一名成员是生物医学工程师。这个人被瓦哈卡市市长要求设计一个项目,使城市中心无障碍。采用了墨西哥标准。
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Proceedings of the 15th Annual International Conference of the IEEE Engineering in Medicine and Biology Societ
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