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2006 3rd IEEE/EMBS International Summer School on Medical Devices and Biosensors最新文献

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Unobtrusive Body Movement Monitoring during Sleep using Infrared Motion Detector and ZigBee Protocol 使用红外运动探测器和ZigBee协议监测睡眠期间不显眼的身体运动
Pub Date : 2006-09-01 DOI: 10.1109/ISSMDBS.2006.360090
J. M. Choi, B. O. Kim, B. Hwang, R. Sohn, K. S. Park
This study was designed to assess body movement during sleep at night unobtrusively using an infrared motion detector and ZigBee communication module. In order to validate the accuracy of this system, motion records and actigraphic data were obtained simultaneously from three young healthy people for three or more consecutive nights. Significant agreement between two data was found by statistical analysis. This body movement monitoring system can assess sleep behaviors on bed without any intervention. Zigbee protocol has an advantage of low power consumption and is suitable for this application.
本研究旨在使用红外运动检测器和ZigBee通信模块来评估夜间睡眠时的身体运动。为了验证该系统的准确性,从三个健康的年轻人连续三个或三个以上的晚上同时获得运动记录和活动数据。经统计分析,两组数据具有显著的一致性。这种身体运动监测系统可以在没有任何干预的情况下评估床上的睡眠行为。Zigbee协议具有低功耗的优点,非常适合这种应用。
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引用次数: 9
Modeling of Pulse Transit Time under the Effects of Hydrostatic Pressure for Cuffless Blood Pressure Measurements 无袖带血压测量中静水压作用下脉搏传递时间的建模
Pub Date : 2006-09-01 DOI: 10.1109/ISSMDBS.2006.360098
Carmen C. Y. Poon, Yuan-ting Zhang, Yinbo Liu
The pulse transit time (PTT)-based approach has been proposed as a noninvasive and cuffless alternative to the conventional occluding-cuff approaches to be used in wearable medical devices for long-term and continuous monitoring of blood pressure (BP). Nevertheless, the PTT-based technique requires an individualized calibration procedure. In order to derive a simple procedure for estimating individualized coefficients for this approach, this paper aims to model PTT under the effects of hydrostatic pressure due to hand elevation. In this study, 11 volunteers were recruited. BP and PTT were measured while the subjects elevated their hands to specific heights above heart level (h). The results of the study show that PTT changes significantly with h (p<0.05) and the relationship between them generally agrees with that derives from the theoretical model. This suggests that using the proposed model, individualized coefficients for estimating BP by the PTT-based approach can be obtained from some simple movements such as hand elevation.
基于脉冲传递时间(PTT)的方法已被提出作为传统封闭袖带方法的无创和无袖带替代方法,用于可穿戴医疗设备中长期连续监测血压(BP)。然而,基于ptt的技术需要个性化的校准程序。为了推导出一种估算该方法个性化系数的简单方法,本文旨在对手抬高引起的静水压力影响下的PTT进行建模。在这项研究中,11名志愿者被招募。当被试将手高举到高于心脏水平(h)的特定高度时,测量血压和PTT。研究结果表明,PTT随h的变化有显著性变化(p<0.05),两者之间的关系与理论模型基本一致。这表明,使用该模型,基于ptt的方法可以从一些简单的动作(如手部抬高)中获得个性化的BP系数。
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引用次数: 39
Using GVF Snake to Segment Liver from CT Images 利用GVF Snake从CT图像中分割肝脏
Pub Date : 2006-09-01 DOI: 10.1109/ISSMDBS.2006.360120
Shaohui Huang, Boliang Wang, Xiaoyang Huang
Liver segmentation on computed tomography (CT) images is a challenging task because the images are often corrupted by noise and sampling artifacts. Thus we choose GVF snake to perform the task. Unfortunately, GVF snake use Gaussian function to generate the edge map. We find that this often cause new problems such as blur the liver boundary. To avoid this, a Canny edge detector is a good choice. Another problem during the segmentation is that GVF snake cannot works well with bad initialization, especially when encounter deep concavities. Fortunately we find that if the initial contour can cross the "bottleneck" of the deep concave, it can easily reach the boundary of liver. Thus an algorithm was developed to generate the initial contour automatically. We introduce a new "maximum force angle map" to evaluate the direction variability of the GVF forces. This map can mark up the "bottleneck " and give a trace to run through it. There may be other trace we do not need in the map. With the help of transcendental knowledge about the liver, such as the position, the shape and the Hounsfield unit range of the liver, the correct trace can be found. The contour of this trace is suitable for using as initial contour for GVF snake. By this means we finally segment the liver slice by slice correctly.
计算机断层扫描(CT)图像的肝脏分割是一项具有挑战性的任务,因为图像经常受到噪声和采样伪影的破坏。因此,我们选择GVF蛇来执行任务。不幸的是,GVF snake使用高斯函数来生成边缘映射。我们发现这往往会引起新的问题,如肝边界模糊。为了避免这种情况,精明的边缘检测器是一个很好的选择。分割过程中的另一个问题是初始化不好时GVF蛇形不能很好地工作,特别是遇到深凹时。幸运的是,我们发现如果初始轮廓能越过深凹的“瓶颈”,就很容易到达肝的边界。为此,提出了一种自动生成初始轮廓的算法。我们引入了一种新的“最大力角图”来评估GVF力的方向变异性。该地图可以标记出“瓶颈”,并给出通过它的踪迹。也许地图上还有其他我们不需要的痕迹。借助关于肝脏的先验知识,如肝脏的位置、形状和霍斯菲尔德单位范围,可以找到正确的踪迹。该轨迹轮廓适合作为GVF蛇的初始轮廓。通过这种方法,我们最终正确地切片了肝脏。
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引用次数: 26
Wearable and Wireless Multi-Electrophysiological System 可穿戴无线多电生理系统
Pub Date : 2006-09-01 DOI: 10.1109/ISSMDBS.2006.360103
Peipei Cao, Shan Jia, Xunheng Wang, Jianzhong Zhou
Recently the development in sensor technology, embedded system technology and wireless communication technology have significantly improved the integration of wearable systems, so that we could find new ways to minimize the wearable circuits module, design layers of fabric for wearable system. In our research, we developed a novel multi-electrophysiological (ECG, GSR, SKT) system using wireless wearable technology. Then using this equipment we detected three electrophysiological signals in different emotional episodes. At last we discussed wireless sensor network and the power supply of this practical system.
近年来,传感器技术、嵌入式系统技术和无线通信技术的发展显著提高了可穿戴系统的集成度,从而为可穿戴系统找到了最小化可穿戴电路模块、设计织物层数的新途径。在我们的研究中,我们利用无线可穿戴技术开发了一种新的多电生理(ECG, GSR, SKT)系统。然后我们用这个仪器检测了不同情绪状态下的三种电生理信号。最后对该实用系统的无线传感器网络和电源进行了讨论。
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引用次数: 8
Integration of Wearable Wireless Sensors and Non-Intrusive Wireless in-Home Monitoring System to Collect and Label the Data from Activities of Daily Living 集成可穿戴无线传感器和非侵入式无线家庭监控系统,收集和标记日常生活活动的数据
Pub Date : 2006-09-01 DOI: 10.1109/ISSMDBS.2006.360089
N. Ince, Cheol-Hong Min, A. Tewfik
We describe an inexpensive in-home monitoring system designed to assist patients with traumatic brain injuries plan and execute daily activities. The system consists of fixed and wearable wireless sensors, including motion, pressure, door, flow, accelerometer, magnetometer, temperature, light and sound sensors. The sensors provide information that can be used to localize the patient, detect the activity they are engaged in and interruptions that may prevent them from completing the activity in a timely manner. During the system design and training phase, we augment the system with time stamped video and audio collection to provide a ground truth and label training data.
我们描述了一种廉价的家庭监测系统,旨在帮助创伤性脑损伤患者计划和执行日常活动。该系统由固定和可穿戴无线传感器组成,包括运动、压力、门、流量、加速度计、磁力计、温度、光和声音传感器。传感器提供的信息可用于定位患者,检测他们正在进行的活动以及可能阻止他们及时完成活动的中断。在系统设计和训练阶段,我们用带有时间戳的视频和音频收集来增强系统,以提供一个真实的基础并标记训练数据。
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引用次数: 14
Micropatterned non-invasive dry electrodes for Brain-Computer Interface 用于脑机接口的微图案化无创干电极
Pub Date : 2006-09-01 DOI: 10.1109/ISSMDBS.2006.360099
F. Gramatica, R. Carabalona, M. Casella, C. Cepek, E. Di Fabrizio, M. Di Rienzo, L. Gavioli, M. Matteucci, F. Rizzo, M. Sancrotti
Partially or completely paralyzed patients can benefit from advanced neuro-prostheses in which a continuous recording of electroencephalogram (EEG) is required, operating some processing and classification to control a computer (BCI, brain-computer interfaces). Patients are so allowed to control external devices or to communicate simple messages through the computer, just concentrating their attention on codified movements or on a letter or icon on a digital keyboard. Conventional electrodes usually require skin preparation and application of electrolytic gel for high quality low amplitude biopotentials recordings and are not suitable for being easily used by patient or caregivers at home in BCI or equivalent systems. In this report we describe the fabrication and characterization of dry (gel not required), non-invasive, user-friendly biopotential electrodes. The electrodes consist of a bidimensional array of micro-needles designed to pierce the first dielectric skin layer (stratum corneum) and establishing a direct contact with the living and electrical conducting cells in the epidermis (no blood vessels and nerve terminations). The easy and immediate application of the spiked electrodes makes them also attractive for every surface long-term biosignal measurements, even at patient's home (EEG, electrocardiogram, etc).
部分或完全瘫痪的患者可以从先进的神经假肢中受益,这种假肢需要连续记录脑电图(EEG),进行一些处理和分类,以控制计算机(BCI,脑机接口)。病人可以控制外部设备或通过电脑交流简单的信息,只需将注意力集中在编码的动作或数字键盘上的字母或图标上。传统的电极通常需要皮肤制备和应用电解凝胶来进行高质量的低振幅生物电位记录,并且不适合患者或护理人员在BCI或等效系统中轻松使用。在本报告中,我们描述了干燥(不需要凝胶),非侵入性,用户友好的生物电位电极的制造和表征。电极由微针的二维阵列组成,设计用于刺穿第一介电皮肤层(角质层),并与表皮中的活细胞和导电细胞(没有血管和神经末梢)建立直接接触。尖刺电极的简单和直接的应用使它们对每一个表面的长期生物信号测量也很有吸引力,甚至在病人家里(脑电图,心电图等)。
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引用次数: 8
Fluid Volume Conductance for Determination of Bladder Volume 测定膀胱容积的液体体积电导法
Pub Date : 2006-09-01 DOI: 10.1109/ISSMDBS.2006.360112
B. Gill, P. C. Fletter, P. Zaszczurynski, A. Perlin, D. Yachia, M. Damaser
Clinical urodynamics is the present standard for diagnosing voiding dysfunction. The nonphysiological nature of this exam often hinders symptom reproduction in the laboratory. Currently, a small intrabladder device is being developed to conduct ambulatory urodynamics. This study investigates the feasibility of using fluid volume conductance for the realtime intravesical volume measurement needed in urodynamics. Prototype devices are polymer bodies having 4 electrodes. Electrode configurations and probe geometries were tested in bladder-like latex vessels using saline having conductivity similar to urine. Sensitivity to temperature and fluid concentration were determined using fresh pig bladders in vitro. The voltage across the fluid volume was found to be inversely related to volume. The ideal probe configuration was found to be an ellipsoid having strip electrodes spaced at 25deg. Increasing fluid temperature and concentration increased solution conductivity, significantly decreasing the measured voltage. Urine's dynamic chemical properties therefore necessitate real-time compensation of conductivity in clinical application; which could be accomplished with another smaller electrode array.
临床尿动力学是目前诊断排尿功能障碍的标准。这种检查的非生理性质常常阻碍了实验室症状的再现。目前,正在开发一种小型的膀胱内装置来进行动态尿动力学。本研究探讨了在尿动力学中使用液体体积电导进行实时膀胱内体积测量的可行性。原型装置是具有4个电极的聚合物体。电极配置和探针几何形状在膀胱样乳胶血管中测试,使用具有类似尿液的导电性的生理盐水。用新鲜猪膀胱体外测定对温度和液体浓度的敏感性。发现流体体积上的电压与体积成反比。理想的探针结构被发现是一个椭球,具有间距为25度的条形电极。提高流体温度和浓度会增加溶液的导电性,显著降低测量电压。因此,尿液的动态化学性质需要在临床应用中实时补偿电导率;这可以用另一个更小的电极阵列来完成。
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引用次数: 1
Wireless E-Jacket for Multiparameter Biophysical Monitoring and Telemedicine Applications 多参数生物物理监测和远程医疗应用的无线电子护套
Pub Date : 2006-09-01 DOI: 10.1109/ISSMDBS.2006.360092
S. Nag, D. Sharma
A widespread requirement exists for a low cost and reliable health monitor in the clinical as well as home environment. The e-jacket presented here is an example of a smart clothing system with multiple bioparameter acquisition of electrocardiogram (ECG), pulse oximetry, body motion/tilt and skin temperature. The battery operated circuit has an integrated graphic liquid crystal display (LCD) screen and a 2.4 GHz wireless link. An RS232 interface provides a plug-in port for easy accessibility to remote telemedicine applications. The system incorporates an efficient ARM7 microcontroller to coordinate a list of software tasks with associated time stamp. Comfort analysis and reliability aspects have been carefully studied along with intelligent power conservation schemes. A low cost and reliable tele-medical network is proposed using an innovative e-textile solution.
在临床和家庭环境中,对低成本和可靠的健康监测仪存在着广泛的需求。这里展示的电子夹克是智能服装系统的一个例子,该系统具有多种生物参数采集,包括心电图(ECG)、脉搏血氧仪、身体运动/倾斜和皮肤温度。电池供电电路具有集成图形液晶显示(LCD)屏幕和2.4 GHz无线链路。RS232接口提供了一个插件端口,方便访问远程远程医疗应用程序。该系统采用了一个高效的ARM7微控制器来协调具有相关时间戳的软件任务列表。随着智能节能方案的提出,舒适性分析和可靠性方面也得到了认真的研究。利用一种创新的电子纺织解决方案,提出了一种低成本、可靠的远程医疗网络。
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引用次数: 6
Wireless Body Sensor Network for Continuous Cuff-less Blood Pressure Monitoring 用于连续无袖带血压监测的无线身体传感器网络
Pub Date : 2006-09-01 DOI: 10.1109/ISSMDBS.2006.360085
J. Espina, T. Falck, J. Muehlsteff, X. Aubert
This paper describes an unobtrusive IEEE 802.15.4-based wireless body sensor network (BSN) that enables continuous cuff-less blood pressure monitoring, opening up new perspectives for hypertension diagnosis and treatment, cardio-vascular event detection, and stress monitoring. We estimate the arterial blood pressure based on the pulse arrival time (PAT), which is measured with a waist electrocardiogram (ECG) and an ear photo-plethysmogram (PPG). The PAT measurement requires the synchronization of the wireless sensors' clocks. This is achieved with the flooding time synchronization protocol (FTSP). The evaluation of both the implemented time synchronization and the robustness of the wireless data transmission yielded promising results. Future work will include the study of packet collisions in synchronized IEEE 802.15.4 networks, the enhancement of the BSN with additional context-providing sensors (e.g. accelerometer, magnetometer, thermistor), and the integration of the blood pressure estimation algorithm in a wireless sensor unit.
本文介绍了一种基于IEEE 802.15.4的无线身体传感器网络(BSN),该网络可以实现连续的无袖带血压监测,为高血压诊断和治疗、心血管事件检测和压力监测开辟了新的视角。我们根据脉搏到达时间(PAT)来估计动脉血压,该时间是用腰部心电图(ECG)和耳容积图(PPG)测量的。PAT测量需要无线传感器时钟的同步。这是通过泛洪时间同步协议(FTSP)实现的。对实现的时间同步和无线数据传输的鲁棒性进行了评估,取得了令人满意的结果。未来的工作将包括研究同步IEEE 802.15.4网络中的数据包碰撞,用额外的提供上下文的传感器(例如加速度计、磁力计、热敏电阻)增强BSN,以及在无线传感器单元中集成血压估计算法。
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引用次数: 45
Image Denoising Based on A Mixture of Bivariate Gaussian Models in Complex Wavelet Domain 基于复小波域二元高斯混合模型的图像去噪
Pub Date : 2006-09-01 DOI: 10.1109/ISSMDBS.2006.360121
H. Rabbani, M. Vafadoost, I. Selesnick, S. Gazor
Recently, it has been shown that algorithms exploiting dependencies between coefficients for modeling probability density function (pdf) of wavelet coefficients, could achieve better results for image denoising in wavelet domain compared with the ones based on the independence assumption. In this context, we design a bivariate maximum a posteriori (MAP) estimator which relies on a mixture of bivariate Gaussian models. This model not only is bivariate but also is mixture and therefore, using this new statistical model, we are able to better capture heavy-tailed natures of the data as well as the interscale dependencies of wavelet coefficients. The simulation results show that our proposed technique achieves better performance than several published methods both visually and in terms of peak signal-to-noise ratio (PSNR).
近年来,利用小波系数的概率密度函数(pdf)来建模系数之间的依赖关系的算法比基于独立性假设的算法在小波域图像去噪方面取得了更好的效果。在这种情况下,我们设计了一个二元最大后验(MAP)估计器,它依赖于二元高斯模型的混合。该模型不仅是二元的,而且是混合的,因此,使用这个新的统计模型,我们能够更好地捕获数据的重尾性质以及小波系数的尺度间依赖性。仿真结果表明,无论在视觉上还是在峰值信噪比(PSNR)方面,我们提出的方法都比现有的几种方法具有更好的性能。
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引用次数: 5
期刊
2006 3rd IEEE/EMBS International Summer School on Medical Devices and Biosensors
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