{"title":"Genetics","authors":"Jan Hurst, Richard H. Scott","doi":"10.1201/b19495-15","DOIUrl":"https://doi.org/10.1201/b19495-15","url":null,"abstract":"","PeriodicalId":415868,"journal":{"name":"Great Ormond Street Handbook of Paediatrics","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130843998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Haematology","authors":"Owen P. Smith, I. Hann","doi":"10.1201/b19495-11","DOIUrl":"https://doi.org/10.1201/b19495-11","url":null,"abstract":"","PeriodicalId":415868,"journal":{"name":"Great Ormond Street Handbook of Paediatrics","volume":"89 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122907082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Orthopaedics and Fractures","authors":"D. Eastwood","doi":"10.1201/B19495-21","DOIUrl":"https://doi.org/10.1201/B19495-21","url":null,"abstract":"","PeriodicalId":415868,"journal":{"name":"Great Ormond Street Handbook of Paediatrics","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115420682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Pilkington, K. Nistala, Helen Lachman, P. Brogan
{"title":"Rheumatology","authors":"C. Pilkington, K. Nistala, Helen Lachman, P. Brogan","doi":"10.1201/b19495-17","DOIUrl":"https://doi.org/10.1201/b19495-17","url":null,"abstract":"","PeriodicalId":415868,"journal":{"name":"Great Ormond Street Handbook of Paediatrics","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121540225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Child protection","authors":"Alice Armitage, D. Hodes","doi":"10.1201/b19495-2","DOIUrl":"https://doi.org/10.1201/b19495-2","url":null,"abstract":"","PeriodicalId":415868,"journal":{"name":"Great Ormond Street Handbook of Paediatrics","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124980465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Infectious Diseases","authors":"V. Novelli, D. Shingadia, H. Al-Ansari","doi":"10.1201/b19495-3","DOIUrl":"https://doi.org/10.1201/b19495-3","url":null,"abstract":"","PeriodicalId":415868,"journal":{"name":"Great Ormond Street Handbook of Paediatrics","volume":"85 11","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120904107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Renal Diseases","authors":"S. Marks","doi":"10.1201/b19495-10","DOIUrl":"https://doi.org/10.1201/b19495-10","url":null,"abstract":"","PeriodicalId":415868,"journal":{"name":"Great Ormond Street Handbook of Paediatrics","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121156570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ophthalmology","authors":"K. Nischal","doi":"10.1201/b19495-7","DOIUrl":"https://doi.org/10.1201/b19495-7","url":null,"abstract":"","PeriodicalId":415868,"journal":{"name":"Great Ormond Street Handbook of Paediatrics","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134067234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Immunology (primary Immunodeficiency Syndromes","authors":"S. Strobel, A. Jones","doi":"10.1201/B19495-16","DOIUrl":"https://doi.org/10.1201/B19495-16","url":null,"abstract":"","PeriodicalId":415868,"journal":{"name":"Great Ormond Street Handbook of Paediatrics","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123928850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
1.4 Allergies against house dust mites (HDM), a common aeroallergen, are observed in up to 85% of asthmatic patients worldwide. HDM is an immunologically complex antigen which activates both innate and adaptive immune responses (1). Moreover it was reported that proteinases, such as trypsin-like enzymes, in HDM promoted allergenicity to proteins, resulting in allergic reactions (2). To facilitate allergic asthma research, Chondrex, Inc. provides HDM extract as a clinically relevant allergen for the induction of a mouse asthma model that mimics how asthmatic patients are sensitized with aeroallergens.
{"title":"Allergic Diseases","authors":"Adam Fox, George Du Toit, Stephan Strobel","doi":"10.1201/b19495-23","DOIUrl":"https://doi.org/10.1201/b19495-23","url":null,"abstract":"1.4 Allergies against house dust mites (HDM), a common aeroallergen, are observed in up to 85% of asthmatic patients worldwide. HDM is an immunologically complex antigen which activates both innate and adaptive immune responses (1). Moreover it was reported that proteinases, such as trypsin-like enzymes, in HDM promoted allergenicity to proteins, resulting in allergic reactions (2). To facilitate allergic asthma research, Chondrex, Inc. provides HDM extract as a clinically relevant allergen for the induction of a mouse asthma model that mimics how asthmatic patients are sensitized with aeroallergens.","PeriodicalId":415868,"journal":{"name":"Great Ormond Street Handbook of Paediatrics","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116855059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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