Pub Date : 2023-03-05DOI: 10.29235/1561-8323-2023-67-1-74-82
P. Vityaz, T. F. Grigoreva, V. Zhornik, S. Kovaliova, V. I. Kvashnin, S. Petrova, E. Devyatkina, S. Vosmerikov, I. S. Veremey, N. Lyakhov
The influence of the conditions of mechanical activation of a mixture of Cu–12 wt. % Sn with different content of the modifier Cu9 Al4 on the structural-phase composition and morphology of the formed composites was studied by the methods of X-ray diffraction analysis, optical and electron microscopy. With the mechanochemical introduction of 10 wt. % of the modifying additive into the matrix of mechanosynthesized tin bronze, the product mainly forms a ternary solid solution of aluminum and tin in copper, Al0.05Cu0.9Sn0.05. In the case of 20 wt. % of the modifying additive, the product contains a solid solution of tin in copper Cu0.9Sn0.1 and an intermetallic compound Cu9 Al4. Studies of the mechanical and tribotechnical characteristics of the material obtained by sintering under pressure showed that the intensity of wear of bronze of the mechanochemically synthesized powder Cu–12 wt. % Sn is slightly less than that of industrial bronze BrTPh10-1, the friction coefficient f decreases by a factor of 1.4, and the range of its values is quite wide f = 0.7–0.9. Modification of mechanically synthesized Cu–12 wt. % Sn bronze with the Cu9 Al4 intermetallic compound makes it possible to reduce wear by a factor of 1.4–1.8 and significantly reduces the friction coefficient (by a factor of 2). A stable value of f = 0.5 is achieved for the MA composition Cu–12 wt. % Sn + 20 wt. % Cu9 Al4. The introduction of an intermetallic compound increases the microhardness of the alloys by a factor of 1.6–2.0 (up to Hμ = 2730 MPa) relative to the bronze alloy BrTPh10-1and mechanically synthesized bronze.
{"title":"Mechanochemical modification of tin bronzes with intermetallide Cu9 Al4","authors":"P. Vityaz, T. F. Grigoreva, V. Zhornik, S. Kovaliova, V. I. Kvashnin, S. Petrova, E. Devyatkina, S. Vosmerikov, I. S. Veremey, N. Lyakhov","doi":"10.29235/1561-8323-2023-67-1-74-82","DOIUrl":"https://doi.org/10.29235/1561-8323-2023-67-1-74-82","url":null,"abstract":"The influence of the conditions of mechanical activation of a mixture of Cu–12 wt. % Sn with different content of the modifier Cu9 Al4 on the structural-phase composition and morphology of the formed composites was studied by the methods of X-ray diffraction analysis, optical and electron microscopy. With the mechanochemical introduction of 10 wt. % of the modifying additive into the matrix of mechanosynthesized tin bronze, the product mainly forms a ternary solid solution of aluminum and tin in copper, Al0.05Cu0.9Sn0.05. In the case of 20 wt. % of the modifying additive, the product contains a solid solution of tin in copper Cu0.9Sn0.1 and an intermetallic compound Cu9 Al4. Studies of the mechanical and tribotechnical characteristics of the material obtained by sintering under pressure showed that the intensity of wear of bronze of the mechanochemically synthesized powder Cu–12 wt. % Sn is slightly less than that of industrial bronze BrTPh10-1, the friction coefficient f decreases by a factor of 1.4, and the range of its values is quite wide f = 0.7–0.9. Modification of mechanically synthesized Cu–12 wt. % Sn bronze with the Cu9 Al4 intermetallic compound makes it possible to reduce wear by a factor of 1.4–1.8 and significantly reduces the friction coefficient (by a factor of 2). A stable value of f = 0.5 is achieved for the MA composition Cu–12 wt. % Sn + 20 wt. % Cu9 Al4. The introduction of an intermetallic compound increases the microhardness of the alloys by a factor of 1.6–2.0 (up to Hμ = 2730 MPa) relative to the bronze alloy BrTPh10-1and mechanically synthesized bronze.","PeriodicalId":41825,"journal":{"name":"DOKLADY NATSIONALNOI AKADEMII NAUK BELARUSI","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49072297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-05DOI: 10.29235/1561-8323-2023-67-1-83-88
Z. V. Lovkis
The results of study of the characteristics of new varieties of fruits, root crops, berries, and vegetables that can move in the fluid flow are obtained. Their interaction with the friction surfaces of trays made of various building materials has been studied. The friction coefficients of rolling and sliding of fruits and vegetables on the wetted surfaces of open channels and trays have been established. They can be used in hydraulic calculations when determining the main parameters of a hydraulic transport installation.
{"title":"Experimental determination of the parameters of the hydraulic transport system of fruit and vegetables","authors":"Z. V. Lovkis","doi":"10.29235/1561-8323-2023-67-1-83-88","DOIUrl":"https://doi.org/10.29235/1561-8323-2023-67-1-83-88","url":null,"abstract":"The results of study of the characteristics of new varieties of fruits, root crops, berries, and vegetables that can move in the fluid flow are obtained. Their interaction with the friction surfaces of trays made of various building materials has been studied. The friction coefficients of rolling and sliding of fruits and vegetables on the wetted surfaces of open channels and trays have been established. They can be used in hydraulic calculations when determining the main parameters of a hydraulic transport installation.","PeriodicalId":41825,"journal":{"name":"DOKLADY NATSIONALNOI AKADEMII NAUK BELARUSI","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48828510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-04DOI: 10.29235/1561-8323-2023-67-1-41-50
E. V. Voronkova, V. I. Luksha, J. V. Poliukhovich, O. N. Gukasian, V. M. Zharich, A. Yermishin
The predominance of varieties and parental lines having low male fertility is a characteristic feature of potatoes as a culture with asexual reproduction. The growth of the share of male sterile varieties has been recently noticed as a result of use in breeding interspecific hybrids with sterile-type cytoplasm. It leads to narrowing the genetic basis of modern potato varieties since it limits the choice of pollinators for breeding. The objectives of this research were to assess male fertility characters of 130 potato varieties from the collection of the Institute of Genetics and Cytology of the National Academy of Sciences of Belarus and identify their cytoplasm type using the set of DNA markers. The obtained results are intended for selection of pollinators for conventional breeding of potato, as well as of varieties for production of dihaploids with fertile-type cytoplasm suitable for hybrid breeding at the diploid level. It was revealed that the accessions with T- and D-type cytoplasm prevailed in the collection (46.0 and 35.4 %, respectively), the share of the accessions with W-type cytoplasm was 18.5 %. Most of the effective pollinators were selected among the varieties having T/β-type cytoplasm (44.6 %). The varieties Aksamit, Briz, Dubrava, Uladar, Alwara, Ausonia, Carlita, Fresco, Labadia, Latona, Liu, Lyra, Quarta, Satina, Sissi with this cytoplasm type were selected as most promising for our purposes according to the combination of breeding characters. The potato varieties with D/α-type cytoplasm were present in the collection under study. Approximately one third (32.6 %) was able to produce functionally fertile pollen (PFF), however the level of its fertility was as a rule low. Nevertheless, the varieties Bashkirski, Delfin, Olga and Ponto formed pollen with PFF suitable to guarantee seed production in crosses. Most of the studied varieties with W/α-, W/β-, and W/γ-type cytoplasm were male sterile. The varieties Atlant and Vesna Belaya were revealed among them that were able to produce functionally fertile pollen.
{"title":"Male fertility of varieties of potato whith different cytoplasma type","authors":"E. V. Voronkova, V. I. Luksha, J. V. Poliukhovich, O. N. Gukasian, V. M. Zharich, A. Yermishin","doi":"10.29235/1561-8323-2023-67-1-41-50","DOIUrl":"https://doi.org/10.29235/1561-8323-2023-67-1-41-50","url":null,"abstract":"The predominance of varieties and parental lines having low male fertility is a characteristic feature of potatoes as a culture with asexual reproduction. The growth of the share of male sterile varieties has been recently noticed as a result of use in breeding interspecific hybrids with sterile-type cytoplasm. It leads to narrowing the genetic basis of modern potato varieties since it limits the choice of pollinators for breeding. The objectives of this research were to assess male fertility characters of 130 potato varieties from the collection of the Institute of Genetics and Cytology of the National Academy of Sciences of Belarus and identify their cytoplasm type using the set of DNA markers. The obtained results are intended for selection of pollinators for conventional breeding of potato, as well as of varieties for production of dihaploids with fertile-type cytoplasm suitable for hybrid breeding at the diploid level. It was revealed that the accessions with T- and D-type cytoplasm prevailed in the collection (46.0 and 35.4 %, respectively), the share of the accessions with W-type cytoplasm was 18.5 %. Most of the effective pollinators were selected among the varieties having T/β-type cytoplasm (44.6 %). The varieties Aksamit, Briz, Dubrava, Uladar, Alwara, Ausonia, Carlita, Fresco, Labadia, Latona, Liu, Lyra, Quarta, Satina, Sissi with this cytoplasm type were selected as most promising for our purposes according to the combination of breeding characters. The potato varieties with D/α-type cytoplasm were present in the collection under study. Approximately one third (32.6 %) was able to produce functionally fertile pollen (PFF), however the level of its fertility was as a rule low. Nevertheless, the varieties Bashkirski, Delfin, Olga and Ponto formed pollen with PFF suitable to guarantee seed production in crosses. Most of the studied varieties with W/α-, W/β-, and W/γ-type cytoplasm were male sterile. The varieties Atlant and Vesna Belaya were revealed among them that were able to produce functionally fertile pollen.","PeriodicalId":41825,"journal":{"name":"DOKLADY NATSIONALNOI AKADEMII NAUK BELARUSI","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43727411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-04DOI: 10.29235/1561-8323-2023-67-1-20-26
B. Zalesky
An algorithm to detect moving objects captured by a moving video camera is presented. The algorithm is based on detection of motion on video frames taken by a moving video camera, as well as on finding and analyzing the trajectories of moving objects. A feature of the algorithm is detection on frames of connected areas (clusters) of possible object motion. Then moving points on the detected clusters are found, and those points trajectories are built with help of the optical flow. The trajectories are used as features of moving objects. Only smooth trajectories are exploited for detection of moving objects, and the remaining ones are removed from consideration. An object is considered as moving on the current frame if it contains ends of a sufficient number of trajectories of moving points found on previous frames. The presented algorithm has a low computational complexity, which allows it to be used in real or near real time on small computers that have only a few processors of the ARM architecture without powerful parallel computing tools such as GPUs or neural network processors NPU.
{"title":"Algorithm for detection of moving objects observed by a video camera","authors":"B. Zalesky","doi":"10.29235/1561-8323-2023-67-1-20-26","DOIUrl":"https://doi.org/10.29235/1561-8323-2023-67-1-20-26","url":null,"abstract":"An algorithm to detect moving objects captured by a moving video camera is presented. The algorithm is based on detection of motion on video frames taken by a moving video camera, as well as on finding and analyzing the trajectories of moving objects. A feature of the algorithm is detection on frames of connected areas (clusters) of possible object motion. Then moving points on the detected clusters are found, and those points trajectories are built with help of the optical flow. The trajectories are used as features of moving objects. Only smooth trajectories are exploited for detection of moving objects, and the remaining ones are removed from consideration. An object is considered as moving on the current frame if it contains ends of a sufficient number of trajectories of moving points found on previous frames. The presented algorithm has a low computational complexity, which allows it to be used in real or near real time on small computers that have only a few processors of the ARM architecture without powerful parallel computing tools such as GPUs or neural network processors NPU.","PeriodicalId":41825,"journal":{"name":"DOKLADY NATSIONALNOI AKADEMII NAUK BELARUSI","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46555396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-04DOI: 10.29235/1561-8323-2023-67-1-51-58
V. Lukashevich, V. V. Ponomarev, S. Gubkin, S. M. Mankevich
An important problem of modern clinical biomechanics is to identify complex movement markers that make it possible to evaluate complex motor adaptive reactions regardless of age, gender, and anthropometric deviations. The purpose of the present study was to develop a method for analysis of human motor adaptive reactions based on calculating specific biomechanical markers obtained by performing diverse kinematic tests. The study involved 90 volunteers with a right-leading kinematic side at an age of 18.8 [16.8/20.8] years, with a height of 171.8 [179.2/164.8] cm, a body weight of 65.3 [76.6/58.5] kg, and the ratio of men and women – 5 : 4. During the study, all participants underwent biomechanical analysis using the TESLASUIT remote motion capture suit and performing diverse kinematic tests. In the course of the study, a new method for analyzing human motor adaptive reactions was developed. It is based on calculating specific time markers of the active phase, average angular deviation markers, and inertial kinematic markers. All markers are calculated after each kinematic tests “frontal stability”, “sagittal stability”, “spatial orientation”, and “stimulus identification”. Our survey revealed that specific (p < 0.001) markers of the first test are the time indicators of the active phase, the markers of the second and fourth tests are associated with the average angular deviation parameters, and the specific indicators of the third test can be the inertial kinematics of thighs, legs, and feet.
{"title":"Evaluation of motor adaptation of healthy persons according to space-time kinematics data","authors":"V. Lukashevich, V. V. Ponomarev, S. Gubkin, S. M. Mankevich","doi":"10.29235/1561-8323-2023-67-1-51-58","DOIUrl":"https://doi.org/10.29235/1561-8323-2023-67-1-51-58","url":null,"abstract":"An important problem of modern clinical biomechanics is to identify complex movement markers that make it possible to evaluate complex motor adaptive reactions regardless of age, gender, and anthropometric deviations. The purpose of the present study was to develop a method for analysis of human motor adaptive reactions based on calculating specific biomechanical markers obtained by performing diverse kinematic tests. The study involved 90 volunteers with a right-leading kinematic side at an age of 18.8 [16.8/20.8] years, with a height of 171.8 [179.2/164.8] cm, a body weight of 65.3 [76.6/58.5] kg, and the ratio of men and women – 5 : 4. During the study, all participants underwent biomechanical analysis using the TESLASUIT remote motion capture suit and performing diverse kinematic tests. In the course of the study, a new method for analyzing human motor adaptive reactions was developed. It is based on calculating specific time markers of the active phase, average angular deviation markers, and inertial kinematic markers. All markers are calculated after each kinematic tests “frontal stability”, “sagittal stability”, “spatial orientation”, and “stimulus identification”. Our survey revealed that specific (p < 0.001) markers of the first test are the time indicators of the active phase, the markers of the second and fourth tests are associated with the average angular deviation parameters, and the specific indicators of the third test can be the inertial kinematics of thighs, legs, and feet.","PeriodicalId":41825,"journal":{"name":"DOKLADY NATSIONALNOI AKADEMII NAUK BELARUSI","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46892849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-04DOI: 10.29235/1561-8323-2023-67-1-38-40
V. Urban, V. Veresov
ZAP-70 (Zeta-chain-Associated Protein kinase 70) is a key kinase in the regulation of the adaptive immune response. Zap-70 acts by binding its SH2-domains to the T-cell-associated CD3ζ protein, thus transmitting a T-cell activation signal induced by the interaction of Major Histocompatibility Complex with T-cell Receptor. It has been established that for ZAP-70 kinase activation, the phosphorylation of Tyr315, Tyr319, and Tyr493 is required, however the mechanisms are unclear. In the present study, we use the tools of structural modeling to elucidate the ZAP-70 activation mechanisms.
{"title":"Structural basis of ZAP-70 activation upon phosphorylation of tyrosines 315, 319 and 493","authors":"V. Urban, V. Veresov","doi":"10.29235/1561-8323-2023-67-1-38-40","DOIUrl":"https://doi.org/10.29235/1561-8323-2023-67-1-38-40","url":null,"abstract":"ZAP-70 (Zeta-chain-Associated Protein kinase 70) is a key kinase in the regulation of the adaptive immune response. Zap-70 acts by binding its SH2-domains to the T-cell-associated CD3ζ protein, thus transmitting a T-cell activation signal induced by the interaction of Major Histocompatibility Complex with T-cell Receptor. It has been established that for ZAP-70 kinase activation, the phosphorylation of Tyr315, Tyr319, and Tyr493 is required, however the mechanisms are unclear. In the present study, we use the tools of structural modeling to elucidate the ZAP-70 activation mechanisms.","PeriodicalId":41825,"journal":{"name":"DOKLADY NATSIONALNOI AKADEMII NAUK BELARUSI","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46591664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-04DOI: 10.29235/1561-8323-2023-67-1-27-37
A. Ivanets, D. V. Pecheonсka, V. Prozorovich, T. F. Kouznetsova
Adsorbents based on binary lithium-manganese oxides with the spinel structure of Li1.33Mn1.67O4 were synthesized by using solid-phase, sol-gel, and hydrothermal methods. The effect of the synthesis methods and calcination temperature on the crystal structure, phase composition, textural characteristics, and morphology of prepared adsorbents was established. It was found that the samples obtained by solid-phase and sol-gel methods and calcined at 600 °C were single-phase (Li1.33Mn1.67O4) while the Mn2O3 trace phase was also obtained only in hydrothermal synthesis. The increase in the average crystallite size and the decrease in the specific surface and the total volume of pores were observed during temperature rise in the range from 400 to 800 °C. The samples prepared by sol-gel and hydrothermal methods after at 600 °C calcination had the highest adsorption efficiency of Li+ ions.
{"title":"Synthesis and physicochemical properties of adsorbents based on Li1.33Mn1.67O4","authors":"A. Ivanets, D. V. Pecheonсka, V. Prozorovich, T. F. Kouznetsova","doi":"10.29235/1561-8323-2023-67-1-27-37","DOIUrl":"https://doi.org/10.29235/1561-8323-2023-67-1-27-37","url":null,"abstract":"Adsorbents based on binary lithium-manganese oxides with the spinel structure of Li1.33Mn1.67O4 were synthesized by using solid-phase, sol-gel, and hydrothermal methods. The effect of the synthesis methods and calcination temperature on the crystal structure, phase composition, textural characteristics, and morphology of prepared adsorbents was established. It was found that the samples obtained by solid-phase and sol-gel methods and calcined at 600 °C were single-phase (Li1.33Mn1.67O4) while the Mn2O3 trace phase was also obtained only in hydrothermal synthesis. The increase in the average crystallite size and the decrease in the specific surface and the total volume of pores were observed during temperature rise in the range from 400 to 800 °C. The samples prepared by sol-gel and hydrothermal methods after at 600 °C calcination had the highest adsorption efficiency of Li+ ions.","PeriodicalId":41825,"journal":{"name":"DOKLADY NATSIONALNOI AKADEMII NAUK BELARUSI","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48648029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-04DOI: 10.29235/1561-8323-2023-67-1-66-73
S. Lysenko, P. O. Zaiko
The problem of improving the WRF numerical weather model performance for the territory of Belarus by assimilating the Earth remote sensing data is considered. It is shown that for the winter period, the use of satellite data of high spatial resolution, including on the structure of land use , albedo, leaf index and photosynthetically active radiation absorbed by the underlying surface can reduce a root-mean-square error of the short-term forecast (up to 48 h) of the air surface temperature by 0.53–1.11 °С. For the summer period, on the basis of numerical experiments the optimal correction factor for the land surface albedo was estimated. This made it possible to reduce a root-mean-square error of temperature forecast at the meteorological stations of Belarus for the lead time of +12, +24, +36, and +48 h by an average of 0.30 °С, 0.10 °С, 0.15 °С, and 0.16 °С, respectively.
{"title":"Improving the accuracy of short-term numerical weather forecasts for the territory of Belarus using the mesoscale WRF model and earth remote sensing data","authors":"S. Lysenko, P. O. Zaiko","doi":"10.29235/1561-8323-2023-67-1-66-73","DOIUrl":"https://doi.org/10.29235/1561-8323-2023-67-1-66-73","url":null,"abstract":"The problem of improving the WRF numerical weather model performance for the territory of Belarus by assimilating the Earth remote sensing data is considered. It is shown that for the winter period, the use of satellite data of high spatial resolution, including on the structure of land use , albedo, leaf index and photosynthetically active radiation absorbed by the underlying surface can reduce a root-mean-square error of the short-term forecast (up to 48 h) of the air surface temperature by 0.53–1.11 °С. For the summer period, on the basis of numerical experiments the optimal correction factor for the land surface albedo was estimated. This made it possible to reduce a root-mean-square error of temperature forecast at the meteorological stations of Belarus for the lead time of +12, +24, +36, and +48 h by an average of 0.30 °С, 0.10 °С, 0.15 °С, and 0.16 °С, respectively.","PeriodicalId":41825,"journal":{"name":"DOKLADY NATSIONALNOI AKADEMII NAUK BELARUSI","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42602127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-04DOI: 10.29235/1561-8323-2023-67-1-59-65
O. E. Kuznetsov, V. Tsyrkunov, S. S. Kerimova
Increasing incidence, difficulties in early diagnosis, and a high mortality rate in liver cancer (LC) determine the relevance of studying the mechanisms of its development. The aim of the work is to evaluate the expression of high molecular weight glycoproteins MUC-1, MUC-13 in liver cancer. The object of study is LC tissue samples of 65 patients from the archives and 34 blood serum samples from patients with morphologically confirmed LC. The age of subjects was 26– 97 years. The level of antibodies to MUC-1 and MUC-13 was studied by ELISA. The reference value ranges of MUC-1 (0.250 ± 0.10 ng/ml) and MUC-13 (0.321 ± 0.13 ng/ml) in the blood serum of healthy individuals were established. The concentration of antibodies to MUC-1 and MUC-13 in the blood serum in RP was significantly higher than that in practically healthy individuals. The concentration of MUC-1 and MUC-13 in the LC tumor tissue was higher than that in the blood serum of apparently healthy individuals and LC patients. With a confirmed LC diagnosis, the level of antibodies to MUC-1 in the blood serum, which exceeds 0.373 ng/ml, and the level of antibodies to MUC-13, which is more than 0.939 ng/ml, may indicate a high risk of a tumor process.
{"title":"Mucin expression in liver cancer","authors":"O. E. Kuznetsov, V. Tsyrkunov, S. S. Kerimova","doi":"10.29235/1561-8323-2023-67-1-59-65","DOIUrl":"https://doi.org/10.29235/1561-8323-2023-67-1-59-65","url":null,"abstract":"Increasing incidence, difficulties in early diagnosis, and a high mortality rate in liver cancer (LC) determine the relevance of studying the mechanisms of its development. The aim of the work is to evaluate the expression of high molecular weight glycoproteins MUC-1, MUC-13 in liver cancer. The object of study is LC tissue samples of 65 patients from the archives and 34 blood serum samples from patients with morphologically confirmed LC. The age of subjects was 26– 97 years. The level of antibodies to MUC-1 and MUC-13 was studied by ELISA. The reference value ranges of MUC-1 (0.250 ± 0.10 ng/ml) and MUC-13 (0.321 ± 0.13 ng/ml) in the blood serum of healthy individuals were established. The concentration of antibodies to MUC-1 and MUC-13 in the blood serum in RP was significantly higher than that in practically healthy individuals. The concentration of MUC-1 and MUC-13 in the LC tumor tissue was higher than that in the blood serum of apparently healthy individuals and LC patients. With a confirmed LC diagnosis, the level of antibodies to MUC-1 in the blood serum, which exceeds 0.373 ng/ml, and the level of antibodies to MUC-13, which is more than 0.939 ng/ml, may indicate a high risk of a tumor process.","PeriodicalId":41825,"journal":{"name":"DOKLADY NATSIONALNOI AKADEMII NAUK BELARUSI","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45608618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-03DOI: 10.29235/1561-8323-2023-67-1-14-19
V. I. Korzyuk, J. V. Rudzko
For a one-dimensional mildly quasilinear wave equation given in the upper half-plane, we consider the Cauchy problem. The solution is constructed by the method of characteristics in an implicit analytical form as a solution of some integro-differential equation. The solvability of this equation, as well the smoothness of its solution, is studied. For the problem in question, the uniqueness of the solution is proved and the conditions under which its classical solution exists are established. When given data is not enough smooth a mild solution is constructed.
{"title":"Classical solution of the initial-value problem for a one-dimensional quasilinear wave equation","authors":"V. I. Korzyuk, J. V. Rudzko","doi":"10.29235/1561-8323-2023-67-1-14-19","DOIUrl":"https://doi.org/10.29235/1561-8323-2023-67-1-14-19","url":null,"abstract":"For a one-dimensional mildly quasilinear wave equation given in the upper half-plane, we consider the Cauchy problem. The solution is constructed by the method of characteristics in an implicit analytical form as a solution of some integro-differential equation. The solvability of this equation, as well the smoothness of its solution, is studied. For the problem in question, the uniqueness of the solution is proved and the conditions under which its classical solution exists are established. When given data is not enough smooth a mild solution is constructed.","PeriodicalId":41825,"journal":{"name":"DOKLADY NATSIONALNOI AKADEMII NAUK BELARUSI","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47359000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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