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Assessment of Cardiac Functions and Subclinical Cardiovascular Risk in Children with Urolithiasis: A Pilot Study 儿童泌尿系结石的心功能和亚临床心血管风险评估:一项初步研究
IF 0.3 Pub Date : 2023-06-05 DOI: 10.4274/jus.galenos.2022.2022.0043
A. Elmacı, H. Alp, M. Dönmez
Objective: Information on cardiovascular problems related to childhood urinary stone disease is limited. The aim of this study was to assess the ventricular functions and subclinical cardiovascular risk in children with urolithiasis using echocardiographic measurements. Materials and Methods: Children diagnosed with urolithiasis were prospectively enrolled in the study as well as children with no urinary stone disease were confirmed via urinary ultrasonography. Body mass index and blood pressures were noted, as well as basic serum parameters. Carotid intima media thickness (cIMT), epicardial fat tissue (EFT) thickness and periaortic fat tissue (PFT) thickness were measured via transthoracic echocardiography in addition to pulsed and tissue Doppler imaging. Myocardial performance indexes were also calculated and correlation analyses were conducted. Results: A total of 17 patients (10 boys) with a mean age of 8.57±2.62 years were included in this study. There were 17 children (12 boys) in the control group and their mean age was 9.53±1.72 years. There was no statistically significant difference between the two groups in terms of demographic and laboratory variables. Tissue Doppler echocardiography revealed that Tei indexes of the left ventricle, right ventricle and septum were significantly higher in the study group than in the controls (p<0.001 for all). The cIMT (0.041±0.012 vs. 0.025±0.002), EFT (0.432±0.083 vs. 0.325±0.032) and PFT thicknesses (0.138±0.029 vs. 0.113±0.008) of the study group was statistically higher than the control group (p<0.001, p<0.001 and p=0.002, respectively) indicating a higher CVD risk. Conclusion: Children with urolithiasis had not only biventricular early systolic and diastolic dysfunction but also subclinical atherosclerosis at early ages. Cardiovascular complications should be considered in the follow-up and treatment of children with urolithiasis.
目的:与儿童尿路结石相关的心血管问题的信息有限。本研究的目的是使用超声心动图测量来评估尿石症儿童的心室功能和亚临床心血管风险。材料和方法:前瞻性地将诊断为尿石症的儿童纳入研究,并通过尿液超声检查确认无尿石疾病的儿童。记录了体重指数和血压,以及基本的血清参数。除了脉冲和组织多普勒成像外,还通过经胸超声心动图测量颈动脉内膜-中膜厚度(cIMT)、心外膜脂肪组织(EFT)厚度和皮质周围脂肪组织(PFT)厚度。计算心肌功能指标并进行相关分析。结果:本研究共纳入17名患者(10名男孩),平均年龄8.57±2.62岁。对照组有17名儿童(12名男孩),平均年龄为9.53±1.72岁。在人口统计学和实验室变量方面,两组之间没有统计学上的显著差异。组织多普勒超声心动图显示,研究组左心室、右心室和隔膜的Tei指数显著高于对照组(p均<0.001)。研究组的cIMT(0.041±0.012 vs.0.025±0.002)、EFT(0.432±0.083 vs.0.325±0.032)和PFT厚度(0.138±0.029 vs.0.113±0.008)在统计学上高于对照组(分别为p<0.001、p<0.001和p=0.002),表明CVD风险更高。结论:儿童尿石症早期不仅存在双心室收缩和舒张功能障碍,而且存在亚临床动脉粥样硬化。在儿童尿石症的随访和治疗中应考虑心血管并发症。
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引用次数: 0
Solitary Fibrous Tumor of the Prostate: What is the Optimal Treatment? Description of A Case and Review of the Pertinent Literature 孤立性前列腺纤维性肿瘤:最佳治疗方法是什么?个案描述及相关文献回顾
IF 0.3 Pub Date : 2023-06-05 DOI: 10.4274/jus.galenos.2022.2022.0054
H. Yılmaz, I. E. Avci, C. Özkürkçügil, Emre Özcan, A. Eruyar
A solitary fibrous tumor (SFT) originating from the prostate has been rarely reported, presenting the 44 th case. We evaluated a 44-year-old man who presented with a two-year history of pressure in the lower abdomen. On magnetic resonance imaging, a 48×66 mm, well-circumscribed mass was observed. 12-core prostatic needle biopsy was performed. Histological examination reported hypocellular and hypercellular areas composed of bland spindle cells arranged in a haphazard pattern. One or two mitotic figures were observed per 10 high-power-fields. Immunohistochemistry analysis showed a strong expression of CD34, STAT-6, and vimentin by tumor cells. We conducted a surveillance protocol for the patient due to the avoidance the surgery. Although there was an increase of approximately 2 cm in tumor diameter, no change was detected in tumor cellularity, number of mitosis, and other histopathological findings in complementary prostatic needle biopsy after three years of follow-up. A literature review of all prostatic SFTs was performed on histopathological features, treatment modality, and reported recurrence and progression data to identify optimal treatment. Local recurrence was reported in five (11.6%) cases and metastasis in two (4.7%) cases. Twenty-two patients underwent radical surgery with a negative margin. None of these had local recurrence and metastasis was reported in only one. Palliative surgery was reported in 18 patients, including five with local recurrence. However, six had no local recurrence or metastasis during the reported follow-up period. Careful surveillance can be conducted in informed patients if there is no malignancy in the histopathologic examination. In all other cases, surgery is strongly advised and should be radical rather than palliative.
孤立的纤维性肿瘤(SFT)起源于前列腺已经很少报道,提出了第44例。我们评估了一位44岁的男性,他表现出两年的下腹部压力史。在磁共振成像上,观察到一个48×66 mm,边界清楚的肿块。行12芯前列腺穿刺活检。组织学检查报告细胞少区和细胞多区由淡色梭形细胞组成,排列杂乱无章。每10个高倍视场观察到1或2个有丝分裂象。免疫组化分析显示肿瘤细胞强烈表达CD34、STAT-6和vimentin。由于避免手术,我们对患者进行了监测。虽然肿瘤直径增加了约2cm,但随访3年后,补充前列腺穿刺活检的肿瘤细胞、有丝分裂数及其他组织病理学检查未见变化。对所有前列腺SFTs的文献进行回顾,包括组织病理学特征、治疗方式、报告的复发和进展数据,以确定最佳治疗方法。局部复发5例(11.6%),转移2例(4.7%)。22例患者接受了阴性切缘的根治性手术。这些病例均无局部复发,仅有一例报道有转移。18例患者行姑息性手术,其中5例局部复发。然而,在报告的随访期间,6例没有局部复发或转移。如果在组织病理检查中没有恶性肿瘤,可以在知情的患者中进行仔细的监测。在所有其他情况下,强烈建议手术,手术应该是根治性的,而不是姑息性的。
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引用次数: 0
The Efficacy and Safety of Retrograde Intrarenal Surgery: A Multi-Center Experience of the RIRSearch Group Study 逆行肾内手术的疗效和安全性:risearch小组研究的多中心经验
IF 0.3 Pub Date : 2023-06-05 DOI: 10.4274/jus.galenos.2023.2022.0039
M. Akgül, H. Çakir, Ö. Çınar, O. Özman, C. Başataç, Duygu Sıddıkoğlu, Ç. Doğan, A. B. Başeskioğlu, C. Yazıcı, E. Sancak, H. Akpınar, Bülent Önal
Retrograde intrarenal surgery (RIRS) is a reliable surgical method for the treatment of urinary system stone disease. This study evaluated the effectiveness and safety of RIRS considering more than 1000 cases based on multi-center experience. The size of the stone, stone location and surgical experience could affect the success rate. Although most consequences are mild and rare, there could nevertheless be serious, life-threatening complications.
逆行肾内手术(RIRS)是治疗泌尿系统结石的一种可靠的手术方法。本研究基于多中心经验,考虑了1000多例病例,评估了RIRS的有效性和安全性。结石的大小、位置和手术经验都会影响手术成功率。尽管大多数后果是轻微和罕见的,但仍可能出现严重的、危及生命的并发症。
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引用次数: 0
The Effect of the MAYO Adhesive Probability Score on Intraoperative Parameters in Laparoscopic Live Donor Nephrectomy and Bench Surgery MAYO粘附概率评分对腹腔镜活体供肾及台架手术术中参数的影响
IF 0.3 Pub Date : 2023-03-06 DOI: 10.4274/jus.galenos.2023.2023.0007
S. Akinci, O. Açıkgöz, Mert Altınel
Objective: Mayo Adhesive Probability score (MAP score) is a nephrometry system to predict surgical difficulty using radiologic image-based measurements and interpretations. MAP score is based on two main factors: Perinephric fat thickness at the level of the renal vein and perinephric fat stranding, which was defined as a linear area of soft tissue attenuation in the perinephric space. This study evaluated the efficacy of the MAP score on intraoperative parameters of laparoscopic donor nefrectomy and bench surgery. Materials and Methods: Four hundred twenty-one laparoscopic live-donor nephrectomies (LDN) and subsequent bench surgeries carried out between 2016 and 2022 have been included in this study. Preoperative computerized tomography images of donors were blindly scored for determination of MAP scores. Sex, age, hypertension, cigarette smoking, dyslipidemia, and body mass index (BMI) were evaluated as risk factors for high MAPS. Results: In females and males, the percentage of donors in the high MAPS group was 11.79% and 25.32%, respectively, and the difference between the two groups is statistically significant. Similarly, the percentage of donors in the high MAPS group is higher in smokers (42.57%) compared to non-smokers (8.75%) (p<0.05). Conclusion: Although a high MAP score can lead to longer operative time both in LDN and bench surgery, complications in LDN and bench surgery do not seem to be affected by a high MAP score.
目的:Mayo粘连概率评分(MAP评分)是一种肾脏测量系统,通过基于放射影像的测量和解释来预测手术难度。MAP评分基于两个主要因素:肾静脉水平的肾周脂肪厚度和肾周脂肪搁浅,肾周脂肪搁浅被定义为肾周间隙软组织衰减的线性区域。本研究评估MAP评分对腹腔镜供肾网切除术和平板手术术中参数的影响。材料和方法:本研究纳入2016年至2022年期间进行的421例腹腔镜活体供体肾切除术(LDN)及随后的台架手术。对供体术前计算机断层图像进行盲目评分,以确定MAP评分。性别、年龄、高血压、吸烟、血脂异常和身体质量指数(BMI)被评价为高MAPS的危险因素。结果:在女性和男性中,高MAPS组的献血者比例分别为11.79%和25.32%,两组差异有统计学意义。同样,高map组中吸烟者的捐献比例(42.57%)高于非吸烟者(8.75%)(p<0.05)。结论:虽然高MAP评分会导致LDN和长凳手术的手术时间延长,但高MAP评分似乎不会影响LDN和长凳手术的并发症。
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引用次数: 0
Ventral and One-sided Dorsolateral Onlay Buccal Mucosa Graft Urethroplasty for Simultaneous Penile and Bulbar Urethral Stricture: A Case Report and Review of Literature 腹侧和单侧背外侧颊粘膜移植物尿道成形术治疗阴茎和延髓尿道狭窄1例报告并文献复习
IF 0.3 Pub Date : 2023-03-01 DOI: 10.4274/jus.galenos.2022.2022.0021
M. Kutluhan, S. Ünal, A. Özayar, E. Okulu, Ö. Kayıgil
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引用次数: 0
Effect of Ultrasound-guided Obturator Nerve Block on Complications in Transurethral Resection for Bladder Cancer 超声引导下闭孔神经阻滞对膀胱癌症经尿道切除术并发症的影响
IF 0.3 Pub Date : 2023-03-01 DOI: 10.4274/jus.galenos.2022.2022.0029
H. Topcu, Cemil Aydın, A. Şentürk, Özgür Yağan
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引用次数: 0
Torsion of the Testis or Appendix Testis? An Analysis of Presentation, Management and Outcome of Acute Scrotum in Children 睾丸扭转还是睾丸附件扭转?儿童急性阴囊的表现、处理及预后分析
IF 0.3 Pub Date : 2023-03-01 DOI: 10.4274/jus.galenos.2022.2022.0022
R. Müller, A. K. Lindner, C. Mayerhofer, G. Laimer, F. Aigner, C. Radmayr
{"title":"Torsion of the Testis or Appendix Testis? An Analysis of Presentation, Management and Outcome of Acute Scrotum in Children","authors":"R. Müller, A. K. Lindner, C. Mayerhofer, G. Laimer, F. Aigner, C. Radmayr","doi":"10.4274/jus.galenos.2022.2022.0022","DOIUrl":"https://doi.org/10.4274/jus.galenos.2022.2022.0022","url":null,"abstract":"","PeriodicalId":42050,"journal":{"name":"Journal of Urological Surgery","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42672285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Dynamic Thiol/Disulfide Homeostasis in Patients with Non-Muscle Invasive Bladder Tumor 非肌肉浸润性膀胱肿瘤患者动态硫/二硫稳态的评价
IF 0.3 Pub Date : 2023-03-01 DOI: 10.4274/jus.galenos.2022.2022.0033
Salih Bürlukkara, Özer Baran, A. Aykaç, M. M. Sunay
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引用次数: 0
Does the Daily Dose of Tadalafil for the Treatment of Erectile Dysfunction Increase Penile Sensation? 每日剂量的他达拉非治疗勃起功能障碍会增加阴茎感觉吗?
IF 0.3 Pub Date : 2023-03-01 DOI: 10.4274/jus.galenos.2022.2022.0042
S. Taş, E. Islamoglu, A. Eren, M. Savaş
{"title":"Does the Daily Dose of Tadalafil for the Treatment of Erectile Dysfunction Increase Penile Sensation?","authors":"S. Taş, E. Islamoglu, A. Eren, M. Savaş","doi":"10.4274/jus.galenos.2022.2022.0042","DOIUrl":"https://doi.org/10.4274/jus.galenos.2022.2022.0042","url":null,"abstract":"","PeriodicalId":42050,"journal":{"name":"Journal of Urological Surgery","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48038373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Duloxetine in the Treatment of Women with Urinary Incontinence: A Systematic Review and Meta-analysis of Efficacy Data from Randomized Controlled Clinical Trials 度洛西汀治疗女性尿失禁:随机对照临床试验疗效数据的系统回顾和荟萃分析
IF 0.3 Pub Date : 2023-03-01 DOI: 10.4274/jus.galenos.2022.2022.0027
N. Mangır, M. Uçar, Ö. Gülpınar, C. Özkürkçügil, O. Demirkesen, T. Tarcan
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引用次数: 0
期刊
Journal of Urological Surgery
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