Pub Date : 2017-11-14DOI: 10.5262/tndt.2017.1003.21
B. Demir, Caner Alparslan, F. Mutlubaş, Onder Yavascan, Duygu Ertan, D. Alaygut, Serdar Sarıtaş, Nejat Aksu
Peritonitis associated with gram-negative bacteria presents difficulties in the follow-up of patients with chronic peritoneal dialysis. Especially in perionitis related to Pseudomonas spp., treatment becomes difficult and may lead to catheter removal. However, some strains may differ. Here, we present a 14-year-old girl with P. putida peritonitis while on automated peritoneal dialysis due to familial Mediterranean fever (FMF)-related amyloidosis and end-stage renal failure. The patient was admitted with abdominal pain, fever, vomiting and cloudy peritoneal fluid starting one day before the admission. She was diagnosed with peritonitis when additional large amounts of leukocytes with 100% polymorphic nucleated cells were found in the peritoneal fluid. Intraperitoneal cefepime treatment was instituted empirically and systemic cefepime was added for up to three days when catheter dysfunction developed. The peritoneal fluid culture yielded cefepime sensitive P. putida and the treatment was stopped at the end of two weeks. No peritonitis recurrence or technical survival problem was found in the follow-up period. It was thought that infection with P. putida , which is thought to be an opportunistic pathogen with low virulence and high response to antibiotic therapy seen in immunosuppressive patients, may be related to canakinumab, which was being used by our case. The case was presented with the aim of drawing attention to the fact that although a pseudomonal peritonitis, two weeks of cefepime monotherapy may be sufficient for P. putida peritonitis.
{"title":"Çocuklarda Aletli Periton Diyalizi Tedavisinde Nadir Görülen Bir Peritonit Etkeni: Pseudomonas Putida","authors":"B. Demir, Caner Alparslan, F. Mutlubaş, Onder Yavascan, Duygu Ertan, D. Alaygut, Serdar Sarıtaş, Nejat Aksu","doi":"10.5262/tndt.2017.1003.21","DOIUrl":"https://doi.org/10.5262/tndt.2017.1003.21","url":null,"abstract":"Peritonitis associated with gram-negative bacteria presents difficulties in the follow-up of patients with chronic peritoneal dialysis. Especially in perionitis related to Pseudomonas spp., treatment becomes difficult and may lead to catheter removal. However, some strains may differ. Here, we present a 14-year-old girl with P. putida peritonitis while on automated peritoneal dialysis due to familial Mediterranean fever (FMF)-related amyloidosis and end-stage renal failure. The patient was admitted with abdominal pain, fever, vomiting and cloudy peritoneal fluid starting one day before the admission. She was diagnosed with peritonitis when additional large amounts of leukocytes with 100% polymorphic nucleated cells were found in the peritoneal fluid. Intraperitoneal cefepime treatment was instituted empirically and systemic cefepime was added for up to three days when catheter dysfunction developed. The peritoneal fluid culture yielded cefepime sensitive P. putida and the treatment was stopped at the end of two weeks. No peritonitis recurrence or technical survival problem was found in the follow-up period. It was thought that infection with P. putida , which is thought to be an opportunistic pathogen with low virulence and high response to antibiotic therapy seen in immunosuppressive patients, may be related to canakinumab, which was being used by our case. The case was presented with the aim of drawing attention to the fact that although a pseudomonal peritonitis, two weeks of cefepime monotherapy may be sufficient for P. putida peritonitis.","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46909117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-11-14DOI: 10.5262/TNDT.2017.1003.22
Eren Soyaltın, Onder Yavascan, Caner Alparslan, Seçil Arslansoyu Çamlar, D. Alaygut, E. Öncel, F. Mutlubaş, B. Demir
{"title":"Ev Hemodiyalizinde Çocuk Hasta Deneyimi: Olgu Sunumu","authors":"Eren Soyaltın, Onder Yavascan, Caner Alparslan, Seçil Arslansoyu Çamlar, D. Alaygut, E. Öncel, F. Mutlubaş, B. Demir","doi":"10.5262/TNDT.2017.1003.22","DOIUrl":"https://doi.org/10.5262/TNDT.2017.1003.22","url":null,"abstract":"","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46816104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-11-14DOI: 10.5262/TNDT.2017.1003.24
A. Yildiz, A. Ersoy, S. Sag, A. Oruc, Ercan Çiğilli, Y. Ayar, S. Güllülü, C. B. Gul
OBJECTIVE: Early arterial stiffness has been shown in autosomal dominant polycystic kidney disease (ADPKD) patients with preserved renal function. However, to our knowledge, no prospective study evaluated changes in arterial functions in patients with ADPKD. The study aimed to monitor the changes in renal and arterial functions in patients with ADPKD with preserved renal functions. MATERIAL and METHODS: A total of 25 ADPKD patients and 12 controls were included in the study. Data on patient characteristics, biochemical parameters and arterial stiffness were recorded at baseline and at the end of fourth year. Determination of independent correlates of the change in eGFR and arterial functions was performed by linear regression analyses. RESULTS: There was a similar decline in renal functions over the study period in both groups. However, arterial functions deteriorated more rapidly in the ADPKD group. Having ADPKD was the only independent factor associated with the decline in arterial functions. CONCLUSION: There were significant decreases in arterial elasticity characteristics in the ADPKD group compared with the control group despite a similar decline in renal functions. Monitoring of arterial stiffness may be as important as monitoring of renal functions in ADPKD patients. KEy wORDS: Autosomal dominant polycystic kidney disease, Cardiovascular disease, Endothelial dysfunction, Arterial stiffness
{"title":"Arterial Function Worsens Faster than Renal Function in Autosomal Dominant Polycystic Kidney Disease","authors":"A. Yildiz, A. Ersoy, S. Sag, A. Oruc, Ercan Çiğilli, Y. Ayar, S. Güllülü, C. B. Gul","doi":"10.5262/TNDT.2017.1003.24","DOIUrl":"https://doi.org/10.5262/TNDT.2017.1003.24","url":null,"abstract":"OBJECTIVE: Early arterial stiffness has been shown in autosomal dominant polycystic kidney disease (ADPKD) patients with preserved renal function. However, to our knowledge, no prospective study evaluated changes in arterial functions in patients with ADPKD. The study aimed to monitor the changes in renal and arterial functions in patients with ADPKD with preserved renal functions. MATERIAL and METHODS: A total of 25 ADPKD patients and 12 controls were included in the study. Data on patient characteristics, biochemical parameters and arterial stiffness were recorded at baseline and at the end of fourth year. Determination of independent correlates of the change in eGFR and arterial functions was performed by linear regression analyses. RESULTS: There was a similar decline in renal functions over the study period in both groups. However, arterial functions deteriorated more rapidly in the ADPKD group. Having ADPKD was the only independent factor associated with the decline in arterial functions. CONCLUSION: There were significant decreases in arterial elasticity characteristics in the ADPKD group compared with the control group despite a similar decline in renal functions. Monitoring of arterial stiffness may be as important as monitoring of renal functions in ADPKD patients. KEy wORDS: Autosomal dominant polycystic kidney disease, Cardiovascular disease, Endothelial dysfunction, Arterial stiffness","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":"27 1","pages":"44-48"},"PeriodicalIF":0.0,"publicationDate":"2017-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44053408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-11-14DOI: 10.5262/TNDT.2017.1003.20
A. Oruc, A. Yildiz, E. Açıkgöz, M. Gullulu
OBJECTIVE: Oxidative stress (OS) is described as the imbalance of oxidative and anti-oxidative systems towards oxidants and plays a role in the pathogenesis of GN. In many studies, ischemiamodified albumin (IMA) is identified as a sign of OS. However, it has not yet been studied in patients with primary GN in the literature. In the present study, we aimed to determine the role of IMA in the pathogenesis of primary GN. MATERIAL and METHODS: Forty-five primary GN patients were divided into two groups as proliferative GN (PGN) (n= 17, 37.8%) and non-proliferative GN (NPGN) (n= 28, 62.2%) according to the histopathological findings. IMA was studied by the cobalt binding method. Since serum albumin levels are commonly low in patients with GN, we calculated the adjusted IMA (aIMA) according to serum albumin. RESULTS: There was no significant difference between the two groups regarding IMA compared with controls (n= 50). IMA was significantly higher in the PGN group compared with the control and NPGN groups (p= 0.009, 0.037; respectively). There was a negative correlation between serum albumin concentration and IMA. CONCLUSION: These results support the role of OS in the pathogenesis of PGN in which inflammatory immune glomerular injury is predominant. KEy wORDS: Glomerulonephritis, Oxidative stress, Ischemia-modified albumin (IMA)
{"title":"Evaluation of Oxidative Stress in Primary Glomerulonephritis with Serum Level of Ischemia Modified Albumin (IMA)","authors":"A. Oruc, A. Yildiz, E. Açıkgöz, M. Gullulu","doi":"10.5262/TNDT.2017.1003.20","DOIUrl":"https://doi.org/10.5262/TNDT.2017.1003.20","url":null,"abstract":"OBJECTIVE: Oxidative stress (OS) is described as the imbalance of oxidative and anti-oxidative systems towards oxidants and plays a role in the pathogenesis of GN. In many studies, ischemiamodified albumin (IMA) is identified as a sign of OS. However, it has not yet been studied in patients with primary GN in the literature. In the present study, we aimed to determine the role of IMA in the pathogenesis of primary GN. MATERIAL and METHODS: Forty-five primary GN patients were divided into two groups as proliferative GN (PGN) (n= 17, 37.8%) and non-proliferative GN (NPGN) (n= 28, 62.2%) according to the histopathological findings. IMA was studied by the cobalt binding method. Since serum albumin levels are commonly low in patients with GN, we calculated the adjusted IMA (aIMA) according to serum albumin. RESULTS: There was no significant difference between the two groups regarding IMA compared with controls (n= 50). IMA was significantly higher in the PGN group compared with the control and NPGN groups (p= 0.009, 0.037; respectively). There was a negative correlation between serum albumin concentration and IMA. CONCLUSION: These results support the role of OS in the pathogenesis of PGN in which inflammatory immune glomerular injury is predominant. KEy wORDS: Glomerulonephritis, Oxidative stress, Ischemia-modified albumin (IMA)","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41409582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-11-14DOI: 10.5262/tndt.2017.1003.23
S. Pehlivan, Nursel Vatansever, A. Oruc, A. Yildiz
{"title":"Sufficiency of YouTube Videos as a Source of Information in Kidney Transplantation","authors":"S. Pehlivan, Nursel Vatansever, A. Oruc, A. Yildiz","doi":"10.5262/tndt.2017.1003.23","DOIUrl":"https://doi.org/10.5262/tndt.2017.1003.23","url":null,"abstract":"","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45740734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-02DOI: 10.5262/tndt.2017.1003.14
Ismail Baloglu, H. Z. Tonbul, N. Selçuk, Kultigin Turkmen
{"title":"Hemodiyaliz Hastalarında İki Farklı Bikarbonat İçerikli Diyalizat Kullanımının Asidoz Kontrolüne Etkisi","authors":"Ismail Baloglu, H. Z. Tonbul, N. Selçuk, Kultigin Turkmen","doi":"10.5262/tndt.2017.1003.14","DOIUrl":"https://doi.org/10.5262/tndt.2017.1003.14","url":null,"abstract":"","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":"26 1","pages":"333-337"},"PeriodicalIF":0.0,"publicationDate":"2017-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48381709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-02DOI: 10.5262/TNDT.2017.1003.03
Ebru Melekoğlu, F. G. Samur
{"title":"Kronik Böbrek Hastalığında Bağırsak Mikrobiyotası ve Diyet Posasının Rolü","authors":"Ebru Melekoğlu, F. G. Samur","doi":"10.5262/TNDT.2017.1003.03","DOIUrl":"https://doi.org/10.5262/TNDT.2017.1003.03","url":null,"abstract":"","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":"26 1","pages":"254-260"},"PeriodicalIF":0.0,"publicationDate":"2017-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42937865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-02DOI: 10.5262/TNDT.2017.1003.13
S. Başcı, A. Ozkok, M. Kaçar, S. Bilgin, A. Odabaş
{"title":"Handgrip Strength and Serum Uric Acid Levels are Associated with Dialysis-Malnutrition Scores in Chronic Hemodialysis Patients","authors":"S. Başcı, A. Ozkok, M. Kaçar, S. Bilgin, A. Odabaş","doi":"10.5262/TNDT.2017.1003.13","DOIUrl":"https://doi.org/10.5262/TNDT.2017.1003.13","url":null,"abstract":"","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":"26 1","pages":"323-332"},"PeriodicalIF":0.0,"publicationDate":"2017-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46082402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：