Pub Date : 2017-10-02DOI: 10.5262/TNDT.2017.1003.17
B. Demir, R. Hall, W. Newman
{"title":"Chronic kidney disease in a boy with enuresis: The diagnosis behind the smile","authors":"B. Demir, R. Hall, W. Newman","doi":"10.5262/TNDT.2017.1003.17","DOIUrl":"https://doi.org/10.5262/TNDT.2017.1003.17","url":null,"abstract":"","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":"26 1","pages":"347-350"},"PeriodicalIF":0.0,"publicationDate":"2017-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47558471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-02DOI: 10.5262/tndt.2017.1003.08
E. Gökçe, Mehtat Unlu, Serkan Yildiz, C. Çavdar, Sülen Sarioğlu, T. Çamsari
OBJECTIvE: The aim of this study was to evaluate the correlation between glomerular C4d staining and the demographic, clinical and histopathological findings in patients with primary membranous nephropathy (MN). MATErIAl and METhOdS: A total of 20 patients who underwent kidney biopsy and diagnosed as MN between 2005 and 2014 were included in this study. Patients were divided into two groups based on to C4d staining degrees and patterns. Those two groups were compared according to their demographical features, clinical follow-up, laboratory follow-up and histopathological findings. rESulTS: The percentage of segmental sclerosis (p=0.017), deposition of immunoglobulin A (p=0.044), and kappa and lambda proteins (p=0.029, p=0.049 respectively) were associated significantly with the negative-mild degree C4d staining group. Staining in a global pattern was statistically associated with intermediate-severe degree of C4d staining (p=0.001). The C4d staining patterns of the patients were then scored (segmental pattern one point, global pattern two point) and multiplied by the degree of C4d staining. The score of segmental/global pattern of staining factor was significantly higher within the intermediate-severe degree of C4d staining group (p<0.01). CONCluSION: Association of the global pattern and intermediate-severe degree of C4d staining suggests that immune deposition is more prevalent within the global pattern in primary MN. kEY wOrdS: C4d, Membranous nephropathy, Kidney injury
{"title":"Birincil Membranöz Nefropatide C4d Varlığı ve Yoğunluğunun Böbrek Hasarlanma Derecesi ile Birlikteliği","authors":"E. Gökçe, Mehtat Unlu, Serkan Yildiz, C. Çavdar, Sülen Sarioğlu, T. Çamsari","doi":"10.5262/tndt.2017.1003.08","DOIUrl":"https://doi.org/10.5262/tndt.2017.1003.08","url":null,"abstract":"OBJECTIvE: The aim of this study was to evaluate the correlation between glomerular C4d staining and the demographic, clinical and histopathological findings in patients with primary membranous nephropathy (MN). MATErIAl and METhOdS: A total of 20 patients who underwent kidney biopsy and diagnosed as MN between 2005 and 2014 were included in this study. Patients were divided into two groups based on to C4d staining degrees and patterns. Those two groups were compared according to their demographical features, clinical follow-up, laboratory follow-up and histopathological findings. rESulTS: The percentage of segmental sclerosis (p=0.017), deposition of immunoglobulin A (p=0.044), and kappa and lambda proteins (p=0.029, p=0.049 respectively) were associated significantly with the negative-mild degree C4d staining group. Staining in a global pattern was statistically associated with intermediate-severe degree of C4d staining (p=0.001). The C4d staining patterns of the patients were then scored (segmental pattern one point, global pattern two point) and multiplied by the degree of C4d staining. The score of segmental/global pattern of staining factor was significantly higher within the intermediate-severe degree of C4d staining group (p<0.01). CONCluSION: Association of the global pattern and intermediate-severe degree of C4d staining suggests that immune deposition is more prevalent within the global pattern in primary MN. kEY wOrdS: C4d, Membranous nephropathy, Kidney injury","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":"26 1","pages":"290-297"},"PeriodicalIF":0.0,"publicationDate":"2017-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43976730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-02DOI: 10.5262/tndt.2017.1003.15
Serkan Yildiz, Mehtat Unlu, C. Çavdar, A. Sifil, Ali Çelik, Sülen Sarioğlu, T. Çamsari
{"title":"Nadir Bir Akut Böbrek Hasarı Nedeni: Kristal Nefropatisi","authors":"Serkan Yildiz, Mehtat Unlu, C. Çavdar, A. Sifil, Ali Çelik, Sülen Sarioğlu, T. Çamsari","doi":"10.5262/tndt.2017.1003.15","DOIUrl":"https://doi.org/10.5262/tndt.2017.1003.15","url":null,"abstract":"","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":"26 1","pages":"338-340"},"PeriodicalIF":0.0,"publicationDate":"2017-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42780351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-02DOI: 10.5262/TNDT.2017.1003.04
Tayfun Birtay, Tonguç Saba, C. Haberal, G. Genctoy
{"title":"Association Between Vascular Access Type and Visceral and Peripheral Body Fat, Nutritional and Inflammatory Parameters in Incident Hemodialysis Patients","authors":"Tayfun Birtay, Tonguç Saba, C. Haberal, G. Genctoy","doi":"10.5262/TNDT.2017.1003.04","DOIUrl":"https://doi.org/10.5262/TNDT.2017.1003.04","url":null,"abstract":"","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":"26 1","pages":"261-270"},"PeriodicalIF":0.0,"publicationDate":"2017-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44813019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-02DOI: 10.5262/tndt.2017.1003.16
Cengiz Zeybek, A. Bolat, H. Orman, I. Yavan, A. Ozcan
1 Health Sciences University, Gülhane Education and Research Hospital, Department of Pediatric Nephrology, Ankara, Turkey 2 Health Sciences University, Gülhane Education and Research Hospital, Department of Pediatrics, Ankara, Turkey 3 Ministry of Health, Gülhane Education and Research Hospital, Department of Pediatric Nephrology, Ankara, Turkey 4 Health Sciences University, Gülhane Education and Research Hospital, Department of Pathology, Ankara, Turkey 5 Yeniyüzyıl University Faculty of Medicine, Department of Pathology, İstanbul, Turkey doi: 10.5262/tndt.2017.1003.16
{"title":"Unusual Fibrillary Glomerulonephritis in a 19-Month-Old Male Patient: A Case Report and Review of the Literature","authors":"Cengiz Zeybek, A. Bolat, H. Orman, I. Yavan, A. Ozcan","doi":"10.5262/tndt.2017.1003.16","DOIUrl":"https://doi.org/10.5262/tndt.2017.1003.16","url":null,"abstract":"1 Health Sciences University, Gülhane Education and Research Hospital, Department of Pediatric Nephrology, Ankara, Turkey 2 Health Sciences University, Gülhane Education and Research Hospital, Department of Pediatrics, Ankara, Turkey 3 Ministry of Health, Gülhane Education and Research Hospital, Department of Pediatric Nephrology, Ankara, Turkey 4 Health Sciences University, Gülhane Education and Research Hospital, Department of Pathology, Ankara, Turkey 5 Yeniyüzyıl University Faculty of Medicine, Department of Pathology, İstanbul, Turkey doi: 10.5262/tndt.2017.1003.16","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":"26 1","pages":"341-346"},"PeriodicalIF":0.0,"publicationDate":"2017-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41652512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-02DOI: 10.5262/TNDT.2017.1003.10
Ç. Şekerci, Yiloren Tanidir, Mahir Bülent Özgen, M. Koç, Cem Akbal, Ferruh Şimşek
{"title":"Retroperitoneal Fibrozis Tedavisi Deneyimi: Marmara Üniversitesi Üroloji ve Nefroloji Bölümlerinin 26 Yıllık Deneyimi","authors":"Ç. Şekerci, Yiloren Tanidir, Mahir Bülent Özgen, M. Koç, Cem Akbal, Ferruh Şimşek","doi":"10.5262/TNDT.2017.1003.10","DOIUrl":"https://doi.org/10.5262/TNDT.2017.1003.10","url":null,"abstract":"","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":"26 1","pages":"305-310"},"PeriodicalIF":0.0,"publicationDate":"2017-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47096948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-02DOI: 10.5262/tndt.2017.1003.12
A. Unal, T. Arıkan, M. Sipahioğlu, I. Kocyiğit, B. Tokgoz, G. Kahriman, O. Oymak
OBJECTIVE: Metastatic infection is a rare but serious complication in patients undergoing hemodialysis (HD). In this retrospective study, we aimed to analyze the clinical aspects, responsible microorganisms, treatments, and clinical outcomes in HD patients with metastatic infection MATERIAL and METHODS: Metastatic infection was defined as infection that occurs at a location physically separate from the portal of entry of the bacteria. We identified 21 metastatic infections in 19 HD patients at our hospital from December 2010 through November 2016. RESULTS: The mean age was 66.4 ± 15.7 years. Twelve (63.2%) of the 19 patients were female whereas 7 (36.8%) patients were male. Type of vascular access was tunneled cuffed permanent catheter in 15 (78.9%) and arteriovenous fistula in 4 (21.1%) patients. The most common type of metastatic infection was spondylodiscitis. In the majority of these patients, the responsible infectious agents were Gram-positive microorganisms including S. epidermidis and S. aureus. The clinical outcome in the majority of the patients was complete recovery. Two patients died due to metastatic infection. CONCLUSION: Metastatic infection in HD patients, especially those with a tunneled cuffed permanent catheter, is a serious complication, which may result in the patient’s death. Gram-positive microorganisms are responsible for the majority of cases with metastatic infection. KEy wORDS: Antibiotic therapy, Hemodialysis, Gram-positive microorganisms, Metastatic infection, Tunneled cuffed permanent catheter Öz AMAÇ: Metastatik enfeksiyon, hemodiyaliz (HD) uygulanan hastalarda nadir ama ciddi bir komplikasyondur. Bu geriye dönük çalışmada, biz metastatik enfeksiyonu olan HD hastalarında klinik görünümleri, sorumlu mikroorganizmaları, tedavileri ve klinik sonuçları analiz etmeyi amaçladık. GEREÇ ve yÖNTEMLER: Metastatik enfeksiyon bakterinin giriş noktasından fiziksel olarak ayrı bir bölgede meydana gelen enfeksiyon olarak tanımlandı. Bizim hastanemizde Aralık 2010 ile Kasım 2016 tarihleri arasında 19 HD hastasında 21 metastatik enfeksiyon tespit edildi. BULGULAR: Ortalama yaş 66.4 ± 15.7 yıldı. On dokuz hastanın 12’si (%63.2) kadın, 7’si (%36.8) erkekti. Damara ulaşım yolunun türü 15 (%78.9) hastada tünelli keçeli kalıcı kateter ve 4 (%21.1) hastada arteriyovenöz fistüldü. En sık görülen metastatik enfeksiyon türü spondilodiskitti. Hastaların çoğunda sorumlu enfeksiyon ajanları S. epidermitis and S. aureus gibi Gram-pozitif mikroorganizmalardı. Hastaların çoğunda klinik sonuç tam iyileşme idi. İki hasta metastatik enfeksiyon nedeniyle kaybedildi. SONUÇ: Özellikle tünelli keçeli kalıcı kateteri olan HD hastalarında metastatik enfeksiyon ciddi bir komplikasyondur ve hastanın kaybedilmesine neden olabilir. Gram-pozitif mikroorganizmalar metastatik enfeksiyonlu olguların çoğundan sorumludur. ANAHTAR SÖzCüKLER: Antibiyotik tedavi, Hemodiyaliz, Gram-pozitif mikroorganizmalar, Metastatik enfeksiyon, Tünelli keçeli kalıcı kateter Correspon
目的:转移性感染是血液透析(HD)患者中一种罕见但严重的并发症。在这项回顾性研究中,我们旨在分析HD患者转移性感染的临床方面、负责的微生物、治疗和临床结果。材料和方法:转移性感染被定义为发生在与细菌入口分离的物理位置的感染。2010年12月至2016年11月,我们在我院的19例HD患者中发现了21例转移性感染。结果:患者平均年龄66.4±15.7岁。其中女性12例(63.2%),男性7例(36.8%)。15例(78.9%)采用隧道式永久导管,4例(21.1%)采用动静脉瘘。最常见的转移性感染类型是脊椎炎。在这些患者中,主要的感染原是革兰氏阳性微生物,包括表皮葡萄球菌和金黄色葡萄球菌。大多数患者的临床结果是完全康复。两名患者死于转移性感染。结论:HD患者的转移性感染是一种严重的并发症,可能导致患者死亡,尤其是那些使用隧道式袖口永久导管的患者。革兰氏阳性微生物是大多数转移性感染病例的原因。关键词:抗生素治疗,血液透析,革兰氏阳性微生物,转移性感染,隧道式永久导管Öz AMAÇ:转移性感染,血液透析(HD),血液病(HD), hastalarda nadir, cdi, komplikasyondur。但geriye dönük çalışmada, biz metastatik enfeksiyonu olan HD hastalarında klinik görünümleri, sorumlu microorganizmalaryi, tedavileri ve klinik sonulari analyiz etmeyi amaçladık。GEREÇ ve yÖNTEMLER: Metastatik enfeksiyon bakterinin giriki noktasından fiziksel olarak ayrbi bölgede meydana gelen enfeksiyon olarak tanımlandı。Bizim hastanemizde Aralık 2010 ile Kasım 2016 tarihleri arasında 19 HD hastasında 21 metastatik enfeksiyon teespit edildi。bulbulular: Ortalama yaku 66.4±15.7 yıldı。在dokuz上hastanın 12 'si (%63.2) kadın, 7 'si (%36.8) erkekti。Damara ulaşım yolunun türü 15 (%78.9) hasada t nelli keeli kalıcı kateter ve 4 (%21.1) hasada arteriyovenöz fistüldü。En sık görülen转移性enfeksiyon türü脊椎病。Hastaların çoğunda金黄色葡萄球菌表皮炎和革兰氏病菌。Hastaların çoğunda klinik sonuç tam iyile idi。İki快速转移性enkekyon nedeniyle kaybedildi。SONUÇ: Özellikle t nelli keeli kalıcı kateteri olan HD hastalarında metastatik enfeksiyon ciddi bir komplikasyondur ve hastanın kaybedilmesine neden olabilir。革兰氏微组织转移瘤enfeksiyonlu olguların çoğundan sorumludur。anhtar SÖzCüKLER: Antibiyotik tedavi, haemdiyaliz, gramm -pozitif microorganizalar, Metastatik enfeksiyon, t nelli keeli kalıcı kateter通讯地址:Aydın nal Erciyes Üniversitesi Tıp fak ltesi, Nefroloji Bilim dalyi,土耳其开塞利电话:+ 90 352 437 93 49 E-mail: aydinunal2003@gmail.com收件日期:08.03.2017接受:21.06.2017 Aydın nal1 Tamer ARIKAN2 Murat Hayri SipAHiOğLU1 ismail KOÇyiğiT1 blent TOKGÖz1 g ven KAHRiMAN3 Oktay OyMAK1 1土耳其开塞利大学医学院肾病科2土耳其开塞利教育与研究医院肾病科3土耳其开塞利大学医学院放射科
{"title":"Metastatic Infections in Hemodialysis: An Analysis of 19 Cases","authors":"A. Unal, T. Arıkan, M. Sipahioğlu, I. Kocyiğit, B. Tokgoz, G. Kahriman, O. Oymak","doi":"10.5262/tndt.2017.1003.12","DOIUrl":"https://doi.org/10.5262/tndt.2017.1003.12","url":null,"abstract":"OBJECTIVE: Metastatic infection is a rare but serious complication in patients undergoing hemodialysis (HD). In this retrospective study, we aimed to analyze the clinical aspects, responsible microorganisms, treatments, and clinical outcomes in HD patients with metastatic infection MATERIAL and METHODS: Metastatic infection was defined as infection that occurs at a location physically separate from the portal of entry of the bacteria. We identified 21 metastatic infections in 19 HD patients at our hospital from December 2010 through November 2016. RESULTS: The mean age was 66.4 ± 15.7 years. Twelve (63.2%) of the 19 patients were female whereas 7 (36.8%) patients were male. Type of vascular access was tunneled cuffed permanent catheter in 15 (78.9%) and arteriovenous fistula in 4 (21.1%) patients. The most common type of metastatic infection was spondylodiscitis. In the majority of these patients, the responsible infectious agents were Gram-positive microorganisms including S. epidermidis and S. aureus. The clinical outcome in the majority of the patients was complete recovery. Two patients died due to metastatic infection. CONCLUSION: Metastatic infection in HD patients, especially those with a tunneled cuffed permanent catheter, is a serious complication, which may result in the patient’s death. Gram-positive microorganisms are responsible for the majority of cases with metastatic infection. KEy wORDS: Antibiotic therapy, Hemodialysis, Gram-positive microorganisms, Metastatic infection, Tunneled cuffed permanent catheter Öz AMAÇ: Metastatik enfeksiyon, hemodiyaliz (HD) uygulanan hastalarda nadir ama ciddi bir komplikasyondur. Bu geriye dönük çalışmada, biz metastatik enfeksiyonu olan HD hastalarında klinik görünümleri, sorumlu mikroorganizmaları, tedavileri ve klinik sonuçları analiz etmeyi amaçladık. GEREÇ ve yÖNTEMLER: Metastatik enfeksiyon bakterinin giriş noktasından fiziksel olarak ayrı bir bölgede meydana gelen enfeksiyon olarak tanımlandı. Bizim hastanemizde Aralık 2010 ile Kasım 2016 tarihleri arasında 19 HD hastasında 21 metastatik enfeksiyon tespit edildi. BULGULAR: Ortalama yaş 66.4 ± 15.7 yıldı. On dokuz hastanın 12’si (%63.2) kadın, 7’si (%36.8) erkekti. Damara ulaşım yolunun türü 15 (%78.9) hastada tünelli keçeli kalıcı kateter ve 4 (%21.1) hastada arteriyovenöz fistüldü. En sık görülen metastatik enfeksiyon türü spondilodiskitti. Hastaların çoğunda sorumlu enfeksiyon ajanları S. epidermitis and S. aureus gibi Gram-pozitif mikroorganizmalardı. Hastaların çoğunda klinik sonuç tam iyileşme idi. İki hasta metastatik enfeksiyon nedeniyle kaybedildi. SONUÇ: Özellikle tünelli keçeli kalıcı kateteri olan HD hastalarında metastatik enfeksiyon ciddi bir komplikasyondur ve hastanın kaybedilmesine neden olabilir. Gram-pozitif mikroorganizmalar metastatik enfeksiyonlu olguların çoğundan sorumludur. ANAHTAR SÖzCüKLER: Antibiyotik tedavi, Hemodiyaliz, Gram-pozitif mikroorganizmalar, Metastatik enfeksiyon, Tünelli keçeli kalıcı kateter Correspon","PeriodicalId":42328,"journal":{"name":"Turkish Nephrology Dialysis and Transplantation Journal","volume":"26 1","pages":"317-322"},"PeriodicalIF":0.0,"publicationDate":"2017-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43547717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}