首页 > 最新文献

Haseki TIp Bulteni-Medical Bulletin of Haseki最新文献

英文 中文
Coexistence of Fibromyalgia, Myofascial Pain Syndrome and Depression Among Patients with Lumbar Disc Herniation 腰椎间盘突出症患者纤维肌痛、肌筋膜疼痛综合征和抑郁的共存
IF 0.3 Q4 Medicine Pub Date : 2022-09-30 DOI: 10.4274/haseki.galenos.2022.8155
Gonca Sağlam, S. Karakullukçu, Hanife Baykal Şahin, Demet Sağlam Aykut
{"title":"Coexistence of Fibromyalgia, Myofascial Pain Syndrome and Depression Among Patients with Lumbar Disc Herniation","authors":"Gonca Sağlam, S. Karakullukçu, Hanife Baykal Şahin, Demet Sağlam Aykut","doi":"10.4274/haseki.galenos.2022.8155","DOIUrl":"https://doi.org/10.4274/haseki.galenos.2022.8155","url":null,"abstract":"","PeriodicalId":42416,"journal":{"name":"Haseki TIp Bulteni-Medical Bulletin of Haseki","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74762005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A Comparative Analysis of Posterior and Lateral Approaches in Hip Hemiarthroplasty of Patients Older than 65 Years Regarding Dislocation and Periprosthetic Fracture Rates 65岁以上患者髋关节置换术后路和外侧入路对脱位和假体周围骨折发生率的比较分析
IF 0.3 Q4 Medicine Pub Date : 2022-09-30 DOI: 10.4274/haseki.galenos.2022.7733
Serkan Önder Sırma, M. Ekinci, Mustafa YILMAZ, M. Sonmez
{"title":"A Comparative Analysis of Posterior and Lateral Approaches in Hip Hemiarthroplasty of Patients Older than 65 Years Regarding Dislocation and Periprosthetic Fracture Rates","authors":"Serkan Önder Sırma, M. Ekinci, Mustafa YILMAZ, M. Sonmez","doi":"10.4274/haseki.galenos.2022.7733","DOIUrl":"https://doi.org/10.4274/haseki.galenos.2022.7733","url":null,"abstract":"","PeriodicalId":42416,"journal":{"name":"Haseki TIp Bulteni-Medical Bulletin of Haseki","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77421993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship Between the Nasopharyngeal Swab Sampling Method, Nasal Obstruction, and SARS-Cov-2 Positivity 鼻咽拭子取样方法、鼻塞与SARS-Cov-2阳性的关系
IF 0.3 Q4 Medicine Pub Date : 2022-09-30 DOI: 10.4274/haseki.galenos.2022.8492
D. Çakan, Zeliha Kubra Cakan, Semih Uşaklıoğlu, Y. Yılmaz, Omer Uysal, Hasan Ahmet Ozdogan
Aim: We think that the nasopharyngeal swab sample should be taken bilaterally to improve the sensitivity of the real-time-reverse transcriptase-polymerase chain reaction (RT-PCR) test since there may be pathologies that cause nasal obstruction, such as nasal septum deviation (NSD). In this context, we investigated the effect of the nasopharyngeal swab sampling method and the presence of nasal obstruction on the detection of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). Method(s): This prospective clinical study was conducted from March 2021 to January 2022. Forty-four hospitalized patients with NSD were included in the study group, and 44 hospitalized patients without NSD were included in the control group. The results of the RT-PCR test studied with a unilateral nasopharyngeal swab sample taken during hospitalization and the RT-PCR test studied with a bilateral nasopharyngeal swab sample taken on the 2nd day of hospitalization and the visual analog scale (VAS) scores showing the patients' pain during the first sampling were determined. Result(s): In the first test, 23 (52.3%) patients in the study group and 32 (72.7%) patients in the control group were evaluated as SARS-CoV-2 positive. The first test sensitivity was significantly higher in the control group (p=0.048). The VAS score was significantly higher in the study group (p=0.00008). In the second test, 35 (79.5%) patients in the study group and 37 (84.1%) patients in the control group were evaluated as SARS-CoV-2 positive. The sensitivity increases in the study group and in the population were statistically significant (p=0.007 and p=0.004, respectively). The consistency of the first and second test results increased in patients without NSD and in patients with low VAS scores [odds ratio (OR)=3.779;p=0.001, OR=2.572;p=0.005, respectively]. Conclusion(s): Nasopharyngeal swab sampling may be affected by nasal congestion and the sampling method. To avoid this, it may be more appropriate to take a nasopharyngeal swab sample through the bilateral nasal cavity. Copyright © 2022 by The Medical Bulletin of Istanbul Haseki Training and Research Hospital The Medical Bulletin of Haseki published by Galenos Yayinevi.
目的:我们认为实时逆转录聚合酶链反应(RT-PCR)检测可能存在鼻中隔偏曲(鼻中隔偏曲)等病理因素,应采用双侧鼻咽拭子取样,以提高检测的灵敏度。在此背景下,我们研究了鼻咽拭子取样方法和鼻塞对检测严重急性呼吸综合征-冠状病毒-2 (SARS-CoV-2)的影响。方法:本前瞻性临床研究于2021年3月至2022年1月进行。44例住院NSD患者纳入研究组,44例未住院NSD患者纳入对照组。采用住院期间单侧鼻咽拭子样本进行RT-PCR检测,采用住院第2天双侧鼻咽拭子样本进行RT-PCR检测,测定第一次取样时患者疼痛的视觉模拟评分(VAS)。结果:在第一次检测中,研究组23例(52.3%)患者和对照组32例(72.7%)患者被评估为SARS-CoV-2阳性。对照组第一次检测的敏感性显著高于对照组(p=0.048)。研究组VAS评分显著高于对照组(p=0.00008)。在第二次检测中,研究组35例(79.5%)和对照组37例(84.1%)被评估为SARS-CoV-2阳性。研究组和人群的敏感性增加有统计学意义(分别为p=0.007和p=0.004)。无NSD患者和VAS评分较低患者的第一次和第二次检测结果的一致性增加[优势比(OR)=3.779;p=0.001, OR=2.572;p=0.005]。结论:鼻咽拭子取样可能受到鼻塞和取样方法的影响。为了避免这种情况,可能更合适的方法是通过双侧鼻腔采集鼻咽拭子样本。伊斯坦布尔Haseki培训和研究医院医学公报版权所有©2022。Galenos Yayinevi出版的Haseki医学公报。
{"title":"Relationship Between the Nasopharyngeal Swab Sampling Method, Nasal Obstruction, and SARS-Cov-2 Positivity","authors":"D. Çakan, Zeliha Kubra Cakan, Semih Uşaklıoğlu, Y. Yılmaz, Omer Uysal, Hasan Ahmet Ozdogan","doi":"10.4274/haseki.galenos.2022.8492","DOIUrl":"https://doi.org/10.4274/haseki.galenos.2022.8492","url":null,"abstract":"Aim: We think that the nasopharyngeal swab sample should be taken bilaterally to improve the sensitivity of the real-time-reverse transcriptase-polymerase chain reaction (RT-PCR) test since there may be pathologies that cause nasal obstruction, such as nasal septum deviation (NSD). In this context, we investigated the effect of the nasopharyngeal swab sampling method and the presence of nasal obstruction on the detection of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). Method(s): This prospective clinical study was conducted from March 2021 to January 2022. Forty-four hospitalized patients with NSD were included in the study group, and 44 hospitalized patients without NSD were included in the control group. The results of the RT-PCR test studied with a unilateral nasopharyngeal swab sample taken during hospitalization and the RT-PCR test studied with a bilateral nasopharyngeal swab sample taken on the 2nd day of hospitalization and the visual analog scale (VAS) scores showing the patients' pain during the first sampling were determined. Result(s): In the first test, 23 (52.3%) patients in the study group and 32 (72.7%) patients in the control group were evaluated as SARS-CoV-2 positive. The first test sensitivity was significantly higher in the control group (p=0.048). The VAS score was significantly higher in the study group (p=0.00008). In the second test, 35 (79.5%) patients in the study group and 37 (84.1%) patients in the control group were evaluated as SARS-CoV-2 positive. The sensitivity increases in the study group and in the population were statistically significant (p=0.007 and p=0.004, respectively). The consistency of the first and second test results increased in patients without NSD and in patients with low VAS scores [odds ratio (OR)=3.779;p=0.001, OR=2.572;p=0.005, respectively]. Conclusion(s): Nasopharyngeal swab sampling may be affected by nasal congestion and the sampling method. To avoid this, it may be more appropriate to take a nasopharyngeal swab sample through the bilateral nasal cavity. Copyright © 2022 by The Medical Bulletin of Istanbul Haseki Training and Research Hospital The Medical Bulletin of Haseki published by Galenos Yayinevi.","PeriodicalId":42416,"journal":{"name":"Haseki TIp Bulteni-Medical Bulletin of Haseki","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79889893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effects of Low-intensity Resistance Training with Blood Flow Restriction Versus Traditional Resistance Exercise on Lower Extremity Muscle Strength, Walking Capacity, and Balance in Ischemic Stroke Survivors: A Study Protocol for the BFR-Stroke RESILIENCE Trial 低强度血流量限制阻力训练与传统阻力训练对缺血性卒中幸存者下肢肌肉力量、行走能力和平衡的影响:bfr -卒中恢复试验的研究方案
IF 0.3 Q4 Medicine Pub Date : 2022-09-30 DOI: 10.4274/haseki.galenos.2022.8361
Ishtiaq Ahmed, R. Mustafaoglu, B. Erhan
{"title":"The Effects of Low-intensity Resistance Training with Blood Flow Restriction Versus Traditional Resistance Exercise on Lower Extremity Muscle Strength, Walking Capacity, and Balance in Ischemic Stroke Survivors: A Study Protocol for the BFR-Stroke RESILIENCE Trial","authors":"Ishtiaq Ahmed, R. Mustafaoglu, B. Erhan","doi":"10.4274/haseki.galenos.2022.8361","DOIUrl":"https://doi.org/10.4274/haseki.galenos.2022.8361","url":null,"abstract":"","PeriodicalId":42416,"journal":{"name":"Haseki TIp Bulteni-Medical Bulletin of Haseki","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76602041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The Relationship Between Bacterial Pathogen Presence Detected by Bronchial Lavage and Acute Rejection: 1-Year Follow-up Results Following Lung Transplantation 肺移植术后1年随访结果:支气管灌洗检测细菌病原体与急性排斥反应的关系
IF 0.3 Q4 Medicine Pub Date : 2022-09-30 DOI: 10.4274/haseki.galenos.2022.8345
Pinar Atagun Guney, Ayse Nigar Halis, Ertan Saribas, S. Citak, M. Vayvada, M. E. Cardak, Yeşim Uygun Kızmaz, A. Taşçı
Aim: Lung transplant recipients are the highest risk group in terms of infective complications among solid organ transplants. It has improved the management of the most common infectious complications with the aid of advances in diagnostic methods, prophylaxis, and therapeutic strategies. In the present study, we evaluated the results of microbiological culture samples by the bronchoscopic method. Methods: This retrospective cohort study included patients who were admitted between November 2016 and May 2019 in a Lung Transplantation Department. We evaluated the results of bacteria detected in the lavage fluid obtained by serial bronchoscopy in the first year after lung transplantation in lung transplant patients. We divided the patients into two groups: those with acute rejection and those without. The two groups were compared according to their culture of growth and analyzed. Results: Of the 77 patients included in the study, 77.2% were male. In the first year after transplantation, 79 bronchoscopic lavage cultures were positive in the follow-up. While bacterial culture positivity by post-transplant bronchial lavage was found to be 62% in the first 3 months, it decreased to 43.6% between the third month and the first year. There was no significant difference between the groups with and without acute rejection of lavage culture growth. Conclusion: This study revealed the importance of the bronchoscopic method in terms of the detection of microbiological findings and the prempitic antibiotic therapy approach in the evaluation of lung infections in lung transplant patients.
目的:肺移植受者是实体器官移植感染并发症的高危人群。随着诊断方法、预防和治疗策略的进步,它改善了对最常见的感染性并发症的管理。在本研究中,我们通过支气管镜方法评估微生物培养样品的结果。方法:本回顾性队列研究纳入了2016年11月至2019年5月在肺移植科住院的患者。我们评估了肺移植患者肺移植后第一年通过连续支气管镜检查获得的灌洗液中细菌的检测结果。我们将患者分为两组:急性排斥反应组和非急性排斥反应组。根据两组的生长培养情况进行比较和分析。结果:纳入研究的77例患者中,77.2%为男性。在移植后的第一年,随访中79例支气管镜灌洗培养阳性。移植后支气管灌洗细菌培养阳性率在前3个月为62%,在第3个月至第1年下降至43.6%。急性排斥组与非急性排斥组之间无显著性差异。结论:本研究揭示了支气管镜方法在肺移植患者肺部感染评估中的微生物学检查和先期抗生素治疗方法的重要性。
{"title":"The Relationship Between Bacterial Pathogen Presence Detected by Bronchial Lavage and Acute Rejection: 1-Year Follow-up Results Following Lung Transplantation","authors":"Pinar Atagun Guney, Ayse Nigar Halis, Ertan Saribas, S. Citak, M. Vayvada, M. E. Cardak, Yeşim Uygun Kızmaz, A. Taşçı","doi":"10.4274/haseki.galenos.2022.8345","DOIUrl":"https://doi.org/10.4274/haseki.galenos.2022.8345","url":null,"abstract":"Aim: Lung transplant recipients are the highest risk group in terms of infective complications among solid organ transplants. It has improved the management of the most common infectious complications with the aid of advances in diagnostic methods, prophylaxis, and therapeutic strategies. In the present study, we evaluated the results of microbiological culture samples by the bronchoscopic method. Methods: This retrospective cohort study included patients who were admitted between November 2016 and May 2019 in a Lung Transplantation Department. We evaluated the results of bacteria detected in the lavage fluid obtained by serial bronchoscopy in the first year after lung transplantation in lung transplant patients. We divided the patients into two groups: those with acute rejection and those without. The two groups were compared according to their culture of growth and analyzed. Results: Of the 77 patients included in the study, 77.2% were male. In the first year after transplantation, 79 bronchoscopic lavage cultures were positive in the follow-up. While bacterial culture positivity by post-transplant bronchial lavage was found to be 62% in the first 3 months, it decreased to 43.6% between the third month and the first year. There was no significant difference between the groups with and without acute rejection of lavage culture growth. Conclusion: This study revealed the importance of the bronchoscopic method in terms of the detection of microbiological findings and the prempitic antibiotic therapy approach in the evaluation of lung infections in lung transplant patients.","PeriodicalId":42416,"journal":{"name":"Haseki TIp Bulteni-Medical Bulletin of Haseki","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73997817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Different Strategies for Prevention of Catheter-Related Bladder Discomfort: A Randomized Controlled Trial 不同预防导尿管相关性膀胱不适策略的比较:一项随机对照试验
IF 0.3 Q4 Medicine Pub Date : 2022-09-30 DOI: 10.4274/haseki.galenos.2022.8421
Fatma Ozkan Sipahioglu, Filiz Karaca Akaslan, Ozge Yamankilic Mumcu, R. Polat, F. Sandikci, A. Donmez
Aim: Catheter-related bladder discomfort (CRBD) is characterized by pain and a burning sensation in the suprapubic region caused by stimulation of type 3 muscarinic (M3) receptors. The aim of this study was to compare the effects of tramadol and dexmedetomidine on CRBD, which have inhibitory effects on the M3 receptor. Methods: A total of 135 male patients with ASA I-II, aged between 18 and 70 years and scheduled to undergo elective retrograde intrarenal surgery between March and July 2020, were included in the study. Patients were randomized into three groups: tramadol (group T), dexmedetomidine (group D), and control (group C). Patients were evaluated for the incidence and severity of CRBD and postoperative pain at the postoperative 0 th (t 0 ), 1 st (t 1 ), 3 rd (t 2 ), and 6 th (t 3 ) hours. Results: The incidence and severity of CRBD were lower in group D at t 1 than in the other groups (p<0.05). The incidence and severity of CRBD were similar between groups T and D, and they were significantly lower than those in group C at t 2 and t 3 (p<0.01). Postoperative pain levels were significantly lower in groups T and D than in group C at t 0 and t 1 (p<0.01). Postoperative recovery time was significantly longer in group D (p<0.01). Conclusion: Both dexmedetomidine and tramadol are effective in preventing CRBD and in postoperative analgesia. Dexmedetomidine is more potent than tramadol in the early period; however, it may delay post-anesthesia recovery time.
目的:导管相关性膀胱不适(CRBD)以耻骨上区疼痛和烧灼感为特征,由3型毒菌碱(M3)受体的刺激引起。本研究的目的是比较曲马多和右美托咪定对CRBD的影响,这两种药物对M3受体有抑制作用。方法:本研究共纳入135例ASA I-II期男性患者,年龄在18岁至70岁之间,计划于2020年3月至7月行选择性逆行肾内手术。患者随机分为曲马多组(T组)、右美托咪定组(D组)和对照组(C组)。分别于术后第0小时(T 0)、第1小时(T 1)、第3小时(T 2)和第6小时(T 3)评价患者CRBD的发生率、严重程度和术后疼痛。结果:D组患者在1 t时CRBD的发生率和严重程度均低于其他组(p<0.05)。T组和D组CRBD的发生率和严重程度相似,且t2、t3时显著低于C组(p<0.01)。T组和D组术后疼痛水平在t0和t1时明显低于C组(p<0.01)。D组术后恢复时间明显延长(p<0.01)。结论:右美托咪定与曲马多均可有效预防CRBD,并可用于术后镇痛。右美托咪定在早期比曲马多更有效;然而,它可能会延迟麻醉后的恢复时间。
{"title":"Comparison of Different Strategies for Prevention of Catheter-Related Bladder Discomfort: A Randomized Controlled Trial","authors":"Fatma Ozkan Sipahioglu, Filiz Karaca Akaslan, Ozge Yamankilic Mumcu, R. Polat, F. Sandikci, A. Donmez","doi":"10.4274/haseki.galenos.2022.8421","DOIUrl":"https://doi.org/10.4274/haseki.galenos.2022.8421","url":null,"abstract":"Aim: Catheter-related bladder discomfort (CRBD) is characterized by pain and a burning sensation in the suprapubic region caused by stimulation of type 3 muscarinic (M3) receptors. The aim of this study was to compare the effects of tramadol and dexmedetomidine on CRBD, which have inhibitory effects on the M3 receptor. Methods: A total of 135 male patients with ASA I-II, aged between 18 and 70 years and scheduled to undergo elective retrograde intrarenal surgery between March and July 2020, were included in the study. Patients were randomized into three groups: tramadol (group T), dexmedetomidine (group D), and control (group C). Patients were evaluated for the incidence and severity of CRBD and postoperative pain at the postoperative 0 th (t 0 ), 1 st (t 1 ), 3 rd (t 2 ), and 6 th (t 3 ) hours. Results: The incidence and severity of CRBD were lower in group D at t 1 than in the other groups (p<0.05). The incidence and severity of CRBD were similar between groups T and D, and they were significantly lower than those in group C at t 2 and t 3 (p<0.01). Postoperative pain levels were significantly lower in groups T and D than in group C at t 0 and t 1 (p<0.01). Postoperative recovery time was significantly longer in group D (p<0.01). Conclusion: Both dexmedetomidine and tramadol are effective in preventing CRBD and in postoperative analgesia. Dexmedetomidine is more potent than tramadol in the early period; however, it may delay post-anesthesia recovery time.","PeriodicalId":42416,"journal":{"name":"Haseki TIp Bulteni-Medical Bulletin of Haseki","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81681706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effects of Different Doses of Tranexamic Acid Infusions on the Postoperative Outcomes of Pediatric Cardiovascular Surgery 不同剂量氨甲环酸输液对小儿心血管手术术后疗效的影响
IF 0.3 Q4 Medicine Pub Date : 2022-09-30 DOI: 10.4274/haseki.galenos.2022.8533
Hatice Dilek Ozcanoglu, Serife Ozalp, Incila Ali Kahraman, S. Sağlam, Behzat Tuzun, Okan Yıldız, E. Ozturk, Funda Gumus Ozcan, A. Hatemi
Aim: There are still concerns about its benefits and possible risks in pediatric patients, as well as the dosage regimen, frequency, and form of tranexamic acid. In this study, the effects of different doses of tranexamic acid used in pediatric congenital heart surgery were investigated. Methods: The study was conducted between August 1, 2020 and April 30, 2021, by screening patient files and hospital data systems. Accordingly, patients in Group TXA-10 and Group TXA-25 were continuously administered 10 mg/kg/hour and 25 mg/kg/ hour tranexamic acid infusions, respectively, from the induction of anesthesia until their transfer to the intensive care unit. The groups were compared in terms of the amount of bleeding, blood products used, and postoperative complications. Results: Thirty-five patients were included in Group TXA-10, and 36 patients were included in Group TXA-25. There was no statistical difference between the groups in terms of gender, weight, height, or presence of cyanotic heart disease. The median post-pump activated clotting time in Group TXA-10 was significantly longer than in Group TXA-25 (153 vs. 141.5 seconds, p=0.003). There was no significant difference between the groups also in terms of the amount of bleeding; the median erythrocyte transfusion amount was 50 ml in both groups. The amount of fresh frozen plasma and platelets that needed to be transfused in Group TXA-10 was higher than in Group TXA-25, albeit not significantly. There was no difference between the groups in terms of postoperative complication rates. Conclusion: Tranexamic acid can be safely and effectively used in pediatric heart surgery cases with an infusion rate of 10 mg/kg/hour.
目的:对于氨甲环酸在儿科患者中的益处和可能的风险,以及氨甲环酸的给药方案、频率和形式,仍然存在担忧。本研究探讨了不同剂量氨甲环酸在小儿先心病手术中的应用效果。方法:通过筛选患者档案和医院数据系统,于2020年8月1日至2021年4月30日进行研究。相应地,TXA-10组和TXA-25组患者从麻醉诱导至转入重症监护病房,分别连续输注10 mg/kg/h和25 mg/kg/h氨甲环酸。两组在出血量、使用的血液制品和术后并发症方面进行比较。结果:35例患者纳入TXA-10组,36例患者纳入TXA-25组。两组之间在性别、体重、身高或是否患有紫绀型心脏病方面没有统计学差异。TXA-10组的中位泵后激活凝血时间明显长于TXA-25组(153秒比141.5秒,p=0.003)。两组之间在出血量方面也没有显著差异;两组中位红细胞输注量均为50 ml。TXA-10组新鲜冷冻血浆和血小板输注量高于TXA-25组,但差异不显著。两组术后并发症发生率无差异。结论:氨甲环酸以10 mg/kg/h滴注量可安全有效地应用于小儿心脏手术病例。
{"title":"The Effects of Different Doses of Tranexamic Acid Infusions on the Postoperative Outcomes of Pediatric Cardiovascular Surgery","authors":"Hatice Dilek Ozcanoglu, Serife Ozalp, Incila Ali Kahraman, S. Sağlam, Behzat Tuzun, Okan Yıldız, E. Ozturk, Funda Gumus Ozcan, A. Hatemi","doi":"10.4274/haseki.galenos.2022.8533","DOIUrl":"https://doi.org/10.4274/haseki.galenos.2022.8533","url":null,"abstract":"Aim: There are still concerns about its benefits and possible risks in pediatric patients, as well as the dosage regimen, frequency, and form of tranexamic acid. In this study, the effects of different doses of tranexamic acid used in pediatric congenital heart surgery were investigated. Methods: The study was conducted between August 1, 2020 and April 30, 2021, by screening patient files and hospital data systems. Accordingly, patients in Group TXA-10 and Group TXA-25 were continuously administered 10 mg/kg/hour and 25 mg/kg/ hour tranexamic acid infusions, respectively, from the induction of anesthesia until their transfer to the intensive care unit. The groups were compared in terms of the amount of bleeding, blood products used, and postoperative complications. Results: Thirty-five patients were included in Group TXA-10, and 36 patients were included in Group TXA-25. There was no statistical difference between the groups in terms of gender, weight, height, or presence of cyanotic heart disease. The median post-pump activated clotting time in Group TXA-10 was significantly longer than in Group TXA-25 (153 vs. 141.5 seconds, p=0.003). There was no significant difference between the groups also in terms of the amount of bleeding; the median erythrocyte transfusion amount was 50 ml in both groups. The amount of fresh frozen plasma and platelets that needed to be transfused in Group TXA-10 was higher than in Group TXA-25, albeit not significantly. There was no difference between the groups in terms of postoperative complication rates. Conclusion: Tranexamic acid can be safely and effectively used in pediatric heart surgery cases with an infusion rate of 10 mg/kg/hour.","PeriodicalId":42416,"journal":{"name":"Haseki TIp Bulteni-Medical Bulletin of Haseki","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82834746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determination of the Relation Between Passive Cigarette Smoking in Children and Respiratory Tract Infections by Evaluation of Urine Cotinine/Creatinine Levels 通过评估尿可替宁/肌酐水平确定儿童被动吸烟与呼吸道感染的关系
IF 0.3 Q4 Medicine Pub Date : 2022-06-27 DOI: 10.4274/haseki.galenos.2022.8045
Sinem Aslan, Ozlem Bostan Gayret, M. Erol, Selen Mandel Isikli, O. Buke, Abdulrahman Ozel
{"title":"Determination of the Relation Between Passive Cigarette Smoking in Children and Respiratory Tract Infections by Evaluation of Urine Cotinine/Creatinine Levels","authors":"Sinem Aslan, Ozlem Bostan Gayret, M. Erol, Selen Mandel Isikli, O. Buke, Abdulrahman Ozel","doi":"10.4274/haseki.galenos.2022.8045","DOIUrl":"https://doi.org/10.4274/haseki.galenos.2022.8045","url":null,"abstract":"","PeriodicalId":42416,"journal":{"name":"Haseki TIp Bulteni-Medical Bulletin of Haseki","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2022-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79513458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Prospective Analysis of the Relationship Between Sexual Dysfunction and Allergic Rhinitis in Men 男性性功能障碍与变应性鼻炎关系的前瞻性分析
IF 0.3 Q4 Medicine Pub Date : 2022-06-27 DOI: 10.4274/haseki.galenos.2022.8346
D. Çakan, Emin Ozturk, Semih Uşaklıoğlu
{"title":"A Prospective Analysis of the Relationship Between Sexual Dysfunction and Allergic Rhinitis in Men","authors":"D. Çakan, Emin Ozturk, Semih Uşaklıoğlu","doi":"10.4274/haseki.galenos.2022.8346","DOIUrl":"https://doi.org/10.4274/haseki.galenos.2022.8346","url":null,"abstract":"","PeriodicalId":42416,"journal":{"name":"Haseki TIp Bulteni-Medical Bulletin of Haseki","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2022-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82323897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The Mental Health and Marital Adjustment of Mothers of Children with Attention Deficit Hyperactivity Disorder 注意缺陷多动障碍患儿母亲的心理健康与婚姻适应
IF 0.3 Q4 Medicine Pub Date : 2022-06-27 DOI: 10.4274/haseki.galenos.2022.8347
Fatma Akyuz Karacan, Semra Yılmaz, Tayfun Kara
{"title":"The Mental Health and Marital Adjustment of Mothers of Children with Attention Deficit Hyperactivity Disorder","authors":"Fatma Akyuz Karacan, Semra Yılmaz, Tayfun Kara","doi":"10.4274/haseki.galenos.2022.8347","DOIUrl":"https://doi.org/10.4274/haseki.galenos.2022.8347","url":null,"abstract":"","PeriodicalId":42416,"journal":{"name":"Haseki TIp Bulteni-Medical Bulletin of Haseki","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2022-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76742674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Haseki TIp Bulteni-Medical Bulletin of Haseki
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1