Pub Date : 2023-03-29DOI: 10.25276/0235-4160-2023-1-25-30
D. Shkvorchenko, E. S. Khrisanfova, D. G. Uzunyan
Relevance. Retinal detachment is a serious disease, that requires immediate surgical treatment. If there is no doubt about the need for urgent surgical treatment, then the question of choosing tamponing substance after retinal immobilization remains open. Often there are no clear criteria for choosing one or another tamponing substance and this issue is determined by the preference of the surgeon. Purpose. To evaluate effectiveness and compare result of surgical treatment of rhegmatogenous retinal detachment using air and C3F8 gas tamponade. Material and methods. Surgical treatment of 43 patients diagnosed with rhegmatogenous retinal detachment was performed and the results of treatment were evaluated. All patients were divided into 2 groups. The first group included 23 patients with the best corrected visual acuity 0.01– 0.9 (±0.06). Surgical treatment of patients from this group was completed with sterile air tamponade. The second group included 20 patients with the best corrected visual acuity of 0.01–0.8 (±0.08). Surgical treatment was completed with a 2.5% C3 F 8 gas tamponade. Results. By the third month of follow-up after surgical treatment B-scan data showed no pathology in all cases of both groups. Visual acuity in group 1 was 0.55-1.0 (±0.063), in group 2 was 0.45–1.0 (±0.061). Light sensitivity in group 1 was 24.5–30.1 (±0.34) dB, in group 2 was 23.1–27.7 (±0.41) dB. Conclusion. Given the comparable clinical results, air tamponade in surgery for rhegmatogenous retinal detachment is preferable than using 2.5% C 3 F 8 gas tamponade. Key words: rhegmatogenous retinal detachment, surgical treatment, air tamponade, C3F8 gas tamponade
{"title":"Surgical treatment of rhegmatogenous retinal detachment using air tamponade and C3F8 gas tamponade","authors":"D. Shkvorchenko, E. S. Khrisanfova, D. G. Uzunyan","doi":"10.25276/0235-4160-2023-1-25-30","DOIUrl":"https://doi.org/10.25276/0235-4160-2023-1-25-30","url":null,"abstract":"Relevance. Retinal detachment is a serious disease, that requires immediate surgical treatment. If there is no doubt about the need for urgent surgical treatment, then the question of choosing tamponing substance after retinal immobilization remains open. Often there are no clear criteria for choosing one or another tamponing substance and this issue is determined by the preference of the surgeon. Purpose. To evaluate effectiveness and compare result of surgical treatment of rhegmatogenous retinal detachment using air and C3F8 gas tamponade. Material and methods. Surgical treatment of 43 patients diagnosed with rhegmatogenous retinal detachment was performed and the results of treatment were evaluated. All patients were divided into 2 groups. The first group included 23 patients with the best corrected visual acuity 0.01– 0.9 (±0.06). Surgical treatment of patients from this group was completed with sterile air tamponade. The second group included 20 patients with the best corrected visual acuity of 0.01–0.8 (±0.08). Surgical treatment was completed with a 2.5% C3 F 8 gas tamponade. Results. By the third month of follow-up after surgical treatment B-scan data showed no pathology in all cases of both groups. Visual acuity in group 1 was 0.55-1.0 (±0.063), in group 2 was 0.45–1.0 (±0.061). Light sensitivity in group 1 was 24.5–30.1 (±0.34) dB, in group 2 was 23.1–27.7 (±0.41) dB. Conclusion. Given the comparable clinical results, air tamponade in surgery for rhegmatogenous retinal detachment is preferable than using 2.5% C 3 F 8 gas tamponade. Key words: rhegmatogenous retinal detachment, surgical treatment, air tamponade, C3F8 gas tamponade","PeriodicalId":424200,"journal":{"name":"Fyodorov journal of ophthalmic surgery","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123219806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-29DOI: 10.25276/0235-4160-2023-1-18-24
A. Yarovoy, D. Volodin, R. A. Loginov
Purpose. To evaluate the efficacy of transscleral thermotherapy (TSTT) in eight patients with retinoblastoma (Rb). Material and methods. In total, 8 patients (9 eyes, 22 tumors) with Rb were treated by TSTT. The average age at the time of treatment was 28 months (from 10 to 45 months). Bilateral Rb was observed in six patients, unilateral – in two. All tumors had preequatorial localization (7 foci – on the mid periphery and 15 – on the far periphery of the fundus). The number of tumors in one eye varied from 1 to 6. The mean tumor thickness was 0.7 mm (from 0.5 to 1.4), the mean basal diameter was 1.5 mm (from 1.0 to 2.9). TSTT was performed transconjunctivally using a diode laser with the following parameters: wavelength – 810 nm, spot diameter – 1000 microns, power from 200 to 500 MW (average – 350 MW), exposure – from 3 to 15 seconds in the scanning mode. Results. Complete tumor regression after TSTT was achieved in 86% of cases (19 tumors). In one case (5%) an incomplete tumor regression was observed and transpupillary thermotherapy was performed. In two cases (9%) continued tumor growth occurred, which required the use of cryotherapy. Overall local tumor control was achieved in all cases (22 tumors). All eyes are preserved, all patients included in the study are alive without distant metastases. No complications from both the anterior and posterior segments, as well as visual signs of scleral damage were not observed in any case. The follow–up period after TSTT ranged from 3 to 11 months (mean – 6 months). Conclusion. First experience of TSTT showed that this method is very promising and can be used to treat small Rb of preequatorial localization in the absence of risk of damage to the iris and equator of the lens, which is the benefit of TSTT compared to transpupillary thermotherapy. Key words: retinoblastoma, transcleral thermotherapy, laser treatment, preequatorial localization, small tumors
{"title":"The first experience of transscleral laser thermotherapy of retinoblastoma","authors":"A. Yarovoy, D. Volodin, R. A. Loginov","doi":"10.25276/0235-4160-2023-1-18-24","DOIUrl":"https://doi.org/10.25276/0235-4160-2023-1-18-24","url":null,"abstract":"Purpose. To evaluate the efficacy of transscleral thermotherapy (TSTT) in eight patients with retinoblastoma (Rb). Material and methods. In total, 8 patients (9 eyes, 22 tumors) with Rb were treated by TSTT. The average age at the time of treatment was 28 months (from 10 to 45 months). Bilateral Rb was observed in six patients, unilateral – in two. All tumors had preequatorial localization (7 foci – on the mid periphery and 15 – on the far periphery of the fundus). The number of tumors in one eye varied from 1 to 6. The mean tumor thickness was 0.7 mm (from 0.5 to 1.4), the mean basal diameter was 1.5 mm (from 1.0 to 2.9). TSTT was performed transconjunctivally using a diode laser with the following parameters: wavelength – 810 nm, spot diameter – 1000 microns, power from 200 to 500 MW (average – 350 MW), exposure – from 3 to 15 seconds in the scanning mode. Results. Complete tumor regression after TSTT was achieved in 86% of cases (19 tumors). In one case (5%) an incomplete tumor regression was observed and transpupillary thermotherapy was performed. In two cases (9%) continued tumor growth occurred, which required the use of cryotherapy. Overall local tumor control was achieved in all cases (22 tumors). All eyes are preserved, all patients included in the study are alive without distant metastases. No complications from both the anterior and posterior segments, as well as visual signs of scleral damage were not observed in any case. The follow–up period after TSTT ranged from 3 to 11 months (mean – 6 months). Conclusion. First experience of TSTT showed that this method is very promising and can be used to treat small Rb of preequatorial localization in the absence of risk of damage to the iris and equator of the lens, which is the benefit of TSTT compared to transpupillary thermotherapy. Key words: retinoblastoma, transcleral thermotherapy, laser treatment, preequatorial localization, small tumors","PeriodicalId":424200,"journal":{"name":"Fyodorov journal of ophthalmic surgery","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131407993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-29DOI: 10.25276/0235-4160-2023-1-31-36
A. Shpak, D. Shkvorchenko, I. Gorshkov, A. V. Yukhananova
Purpose. To perform a comparative evaluation of the efficacy and functional results of surgical treatment of rhegmatogenous retinal detachment (RRD) with breaks in the lower hemisphere using gas or silicone tamponade of the vitreal cavity. Material and methods. Seventy-eight patients (78 eyes) with RRD and the location of breaks in the lower hemisphere were examined. Depending on the nature of retinal detachment patients were divided into 2 groups: without macular detachment («Macula-on») – 36 patients (36 eyes) and with retinal detachment in the macular area («Macula-off») – 42 patients (42 eyes). Each group included two subgroups «Gas» and «Silicone» depending on the type of final vitreal tamponade performed with gas (12% gas-air mixture with perfluoropropane C3F8 ) or silicone (Densiron), respectively. The type of tamponade was chosen randomly. Results. Subgroups of patients with different types of tamponade did not differ from each other in clinical and demographic characteristics. In the postoperative period, a complete retinal attachment was achieved in 75 patients (96%). At 6 months postoperatively, retinal light sensitivity (total and in central point) in the Macula-on group was significantly higher after treatment with gas tamponade compared to the final tamponade with silicone. For other parameters in the Macula-on group, the type of tamponade did not play a significant role. In the Macula-off group, neither functional parameters nor optical coherence tomography data at 6 months depended on the type of tamponade. Conclusion. The use of tamponade with an air-gas mixture and silicone in RRD patients with localization of breaks in the lower hemisphere is equally effective in achieving a high frequency of retinal attachment. Patients with RRD without macular involvement had significantly higher retinal light sensitivity (total and in central point) after treatment with gas-air tamponade compared to final tamponade with silicone. Gas-air tamponade has the advantage of not requiring a second surgical intervention and can be recommended for wide use in RRD patients with breaks in the lower hemisphere without significant proliferative vitreoretinopathy. Key words: rhegmatogenous retinal detachment, inferior hemisphere break, gas tamponade, silicone tamponade, photosensitivity
{"title":"Comparative analysis of surgical treatment of rhegmatogenous retinal detachment with lower localization of breaks with tamponade of the vitreal cavity by gas or silicone","authors":"A. Shpak, D. Shkvorchenko, I. Gorshkov, A. V. Yukhananova","doi":"10.25276/0235-4160-2023-1-31-36","DOIUrl":"https://doi.org/10.25276/0235-4160-2023-1-31-36","url":null,"abstract":"Purpose. To perform a comparative evaluation of the efficacy and functional results of surgical treatment of rhegmatogenous retinal detachment (RRD) with breaks in the lower hemisphere using gas or silicone tamponade of the vitreal cavity. Material and methods. Seventy-eight patients (78 eyes) with RRD and the location of breaks in the lower hemisphere were examined. Depending on the nature of retinal detachment patients were divided into 2 groups: without macular detachment («Macula-on») – 36 patients (36 eyes) and with retinal detachment in the macular area («Macula-off») – 42 patients (42 eyes). Each group included two subgroups «Gas» and «Silicone» depending on the type of final vitreal tamponade performed with gas (12% gas-air mixture with perfluoropropane C3F8 ) or silicone (Densiron), respectively. The type of tamponade was chosen randomly. Results. Subgroups of patients with different types of tamponade did not differ from each other in clinical and demographic characteristics. In the postoperative period, a complete retinal attachment was achieved in 75 patients (96%). At 6 months postoperatively, retinal light sensitivity (total and in central point) in the Macula-on group was significantly higher after treatment with gas tamponade compared to the final tamponade with silicone. For other parameters in the Macula-on group, the type of tamponade did not play a significant role. In the Macula-off group, neither functional parameters nor optical coherence tomography data at 6 months depended on the type of tamponade. Conclusion. The use of tamponade with an air-gas mixture and silicone in RRD patients with localization of breaks in the lower hemisphere is equally effective in achieving a high frequency of retinal attachment. Patients with RRD without macular involvement had significantly higher retinal light sensitivity (total and in central point) after treatment with gas-air tamponade compared to final tamponade with silicone. Gas-air tamponade has the advantage of not requiring a second surgical intervention and can be recommended for wide use in RRD patients with breaks in the lower hemisphere without significant proliferative vitreoretinopathy. Key words: rhegmatogenous retinal detachment, inferior hemisphere break, gas tamponade, silicone tamponade, photosensitivity","PeriodicalId":424200,"journal":{"name":"Fyodorov journal of ophthalmic surgery","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121401595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-29DOI: 10.25276/0235-4160-2023-1-54-60
A. Shevchenko, V. F. Prokof’ev, V. Konenkov, O. V. Ermakova, A. Trunov, V. Chernykh
Relevance. Glaucoma is one of the significant causes of irreversible blindness among aging population around the world. The significant role of matrix metalloproteinases (MMPs) in the remodeling of eye structures during the development of glaucoma is widely discussed in the scientific literature. It is assumed that the polymorphism of the regulatory regions of the genes encoding MMP can affect the level of their expression and contribute to predisposition to the development of the disease. Purpose. To study the features of the polymorphism of the genes of matrix metalloproteinases MMP2, MMP3 and MMP9 in patients with primary open-angle glaucoma. Material and methods. Main group 99 patients with a verified diagnosis of stage II primary open-angle glaucoma. 100 people without glaucoma in anamnesis are included in the control group. Polymorphism of promoter region MMP2 (rs2438650), MMP3 (rs3025058), MMP9 (rs3918242) genes was analyzed. Results. It is shown that minor homozygous genotype MMP2 is significantly more frequent, and heterozygous genotypeMMP2is less frequent among patients with glaucoma. Two complex genotypes which associated with disease were identified. The protective MMP2-1306 TT genotype was confirmed at group of women with glaucoma relative to women without glaucoma and high odds ratio of disease developing for complex genotype MMP2-130 6TC:MMP3-1171 6A6A was shown relative to the general group. Conclusion. The data we obtained on the protective significance of the presence in the human genome of the homozygous variant of the MMP2gene -1306TTallow us to use them in further studies related to risk of occurrence and development of primary open-angle glaucoma. Key words: primary open-angle glaucoma, gene polymorphism, matrix metalloproteinases
{"title":"The analysis of MMP2, MMP3 and MMP9 matrix metalloproteinases genes polymorphism among Russian Caucasian patients with primary open-angle glaucoma","authors":"A. Shevchenko, V. F. Prokof’ev, V. Konenkov, O. V. Ermakova, A. Trunov, V. Chernykh","doi":"10.25276/0235-4160-2023-1-54-60","DOIUrl":"https://doi.org/10.25276/0235-4160-2023-1-54-60","url":null,"abstract":"Relevance. Glaucoma is one of the significant causes of irreversible blindness among aging population around the world. The significant role of matrix metalloproteinases (MMPs) in the remodeling of eye structures during the development of glaucoma is widely discussed in the scientific literature. It is assumed that the polymorphism of the regulatory regions of the genes encoding MMP can affect the level of their expression and contribute to predisposition to the development of the disease. Purpose. To study the features of the polymorphism of the genes of matrix metalloproteinases MMP2, MMP3 and MMP9 in patients with primary open-angle glaucoma. Material and methods. Main group 99 patients with a verified diagnosis of stage II primary open-angle glaucoma. 100 people without glaucoma in anamnesis are included in the control group. Polymorphism of promoter region MMP2 (rs2438650), MMP3 (rs3025058), MMP9 (rs3918242) genes was analyzed. Results. It is shown that minor homozygous genotype MMP2 is significantly more frequent, and heterozygous genotypeMMP2is less frequent among patients with glaucoma. Two complex genotypes which associated with disease were identified. The protective MMP2-1306 TT genotype was confirmed at group of women with glaucoma relative to women without glaucoma and high odds ratio of disease developing for complex genotype MMP2-130 6TC:MMP3-1171 6A6A was shown relative to the general group. Conclusion. The data we obtained on the protective significance of the presence in the human genome of the homozygous variant of the MMP2gene -1306TTallow us to use them in further studies related to risk of occurrence and development of primary open-angle glaucoma. Key words: primary open-angle glaucoma, gene polymorphism, matrix metalloproteinases","PeriodicalId":424200,"journal":{"name":"Fyodorov journal of ophthalmic surgery","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128337870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-29DOI: 10.25276/0235-4160-2023-1-47-53
V. Rudenko, A. Khudyakov, O. V. Kolenko, E. L. Sorokin
Purpose. To evaluate the long-term outcomes of surgery of submacular hemorrhage (SMH) in patients with exudative age-related macular degeneration. Material and methods. A dynamic follow-up of 32 patients with SMH (32 eyes) was carried out, who underwent 25G endovitreal intervention with subretinal injection of 1000 to 3000 IU of the Gemaza drug. The area of the SMH in all cases was extensive with the capture of the fovea. The follow-up period ranged from 24 to 30 months. Results. There was displacement of almost the entire volume of SMH from the macular area to the low periphery in all operated eyes by the next day after the operation. There were complete elimination of SMH and the formation of a normal configuration of the macular profile in 7 days after surgery in all eyes. All patients were satisfied with the results of the surgery according to significant increase of visual acuity and disappearance of a spot in the central visual field. Postoperative complications appeared in four eyes at different times of follow up period, but they were eliminated after reoperation. Conclusion. Subretinal administration of the drug Gemaza and pneumodislocation of the blood clot is an effective method for the treatment of SMH with a limitation period of up to 2 weeks. In the vast majority of cases (88%), it was possible to achieve complete elimination of the SMH and a significant improvement in central vision. Key words: submacular hemorrhage, Gemaza, recombinant prourokinase, age-related macular degeneration, subretinal neovascular membrane
{"title":"Evaluation of the long-term outcomes of surgery of submacular hemorrhage in patients with exudative age-related macular degeneration","authors":"V. Rudenko, A. Khudyakov, O. V. Kolenko, E. L. Sorokin","doi":"10.25276/0235-4160-2023-1-47-53","DOIUrl":"https://doi.org/10.25276/0235-4160-2023-1-47-53","url":null,"abstract":"Purpose. To evaluate the long-term outcomes of surgery of submacular hemorrhage (SMH) in patients with exudative age-related macular degeneration. Material and methods. A dynamic follow-up of 32 patients with SMH (32 eyes) was carried out, who underwent 25G endovitreal intervention with subretinal injection of 1000 to 3000 IU of the Gemaza drug. The area of the SMH in all cases was extensive with the capture of the fovea. The follow-up period ranged from 24 to 30 months. Results. There was displacement of almost the entire volume of SMH from the macular area to the low periphery in all operated eyes by the next day after the operation. There were complete elimination of SMH and the formation of a normal configuration of the macular profile in 7 days after surgery in all eyes. All patients were satisfied with the results of the surgery according to significant increase of visual acuity and disappearance of a spot in the central visual field. Postoperative complications appeared in four eyes at different times of follow up period, but they were eliminated after reoperation. Conclusion. Subretinal administration of the drug Gemaza and pneumodislocation of the blood clot is an effective method for the treatment of SMH with a limitation period of up to 2 weeks. In the vast majority of cases (88%), it was possible to achieve complete elimination of the SMH and a significant improvement in central vision. Key words: submacular hemorrhage, Gemaza, recombinant prourokinase, age-related macular degeneration, subretinal neovascular membrane","PeriodicalId":424200,"journal":{"name":"Fyodorov journal of ophthalmic surgery","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121166209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-29DOI: 10.25276/0235-4160-2023-1-90-96
E. Titarenko, O. V. Shilovskikh, D.I. IIvanov, A. Ulyanov
Relevance. Cataract is the leading cause of visual impairment worldwide. Even in the early stages of cataract development, when the maximum visual acuity often remains high, patients complain of a decrease in image quality (light scattering, diplopia), which is expressed in the difficulty of performing daily and professional activities. The cause of this condition in most cases is internal aberrations of a higher order. One of the topical issues of modern ophthalmology is the definition of indications for surgery of primary cataracts with high visual acuity. Purpose. The purpose of this literature review was to describe the current state of the problem of wavefront changes in patients with various types of initial lens opacity. Material and methods. A systematic analysis of scientific publications of domestic and foreign authors on the resources PubMed, Medline from 2000 to 2022, devoted to the currently existing methods for assessing the quality of vision of patients with initial opacification of the lens, was carried out. Results. Our literature review showed the great importance of assessing wavefront aberrations in patients with initial cataracts and high visual acuity. With the advent of modern diagnostic systems – aberrometers with the possibility of an isolated assessment of internal aberrations, doctors have the opportunity to interpret data on the effect of lens changes on the quality of vision. Conclusion. Visual acuity in patients with initial cataract is not a unique evaluation criterion for determining the timing of surgical intervention. Analysis of wavefront aberrations to a greater extent describe visual impairments and can be used as objective criteria for prescribing surgical treatment. The study of aberrations of the human eye makes it possible to give an objective and quantitative assessment of the optical functions of the eye, which expands the possibilities for diagnosis and for the formation of surgical approaches for initial lens opacities in patients with high visual acuity. Key words: higher-order wavefront aberrations, cataract
{"title":"Modern approaches to cataract surgery based on wavefront analysis","authors":"E. Titarenko, O. V. Shilovskikh, D.I. IIvanov, A. Ulyanov","doi":"10.25276/0235-4160-2023-1-90-96","DOIUrl":"https://doi.org/10.25276/0235-4160-2023-1-90-96","url":null,"abstract":"Relevance. Cataract is the leading cause of visual impairment worldwide. Even in the early stages of cataract development, when the maximum visual acuity often remains high, patients complain of a decrease in image quality (light scattering, diplopia), which is expressed in the difficulty of performing daily and professional activities. The cause of this condition in most cases is internal aberrations of a higher order. One of the topical issues of modern ophthalmology is the definition of indications for surgery of primary cataracts with high visual acuity. Purpose. The purpose of this literature review was to describe the current state of the problem of wavefront changes in patients with various types of initial lens opacity. Material and methods. A systematic analysis of scientific publications of domestic and foreign authors on the resources PubMed, Medline from 2000 to 2022, devoted to the currently existing methods for assessing the quality of vision of patients with initial opacification of the lens, was carried out. Results. Our literature review showed the great importance of assessing wavefront aberrations in patients with initial cataracts and high visual acuity. With the advent of modern diagnostic systems – aberrometers with the possibility of an isolated assessment of internal aberrations, doctors have the opportunity to interpret data on the effect of lens changes on the quality of vision. Conclusion. Visual acuity in patients with initial cataract is not a unique evaluation criterion for determining the timing of surgical intervention. Analysis of wavefront aberrations to a greater extent describe visual impairments and can be used as objective criteria for prescribing surgical treatment. The study of aberrations of the human eye makes it possible to give an objective and quantitative assessment of the optical functions of the eye, which expands the possibilities for diagnosis and for the formation of surgical approaches for initial lens opacities in patients with high visual acuity. Key words: higher-order wavefront aberrations, cataract","PeriodicalId":424200,"journal":{"name":"Fyodorov journal of ophthalmic surgery","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130502266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-29DOI: 10.25276/0235-4160-2023-1-69-75
V. Yartsev, E. L. At’kova
Relevance. Nasolacrimal duct obstruction occurs in 9% of patients after radioiodine therapy for thyroid cancer. The surgical interventions used in this case have not been studied enough; indications for certain operations have not been developed. Purpose. To evaluate clinical efficacy of surgical treatment in patients with nasolacrimal duct obstruction due to radioactive iodine therapy. Material and methods. The outcomes of 47 surgeries in patients with secondary acquired nasolacrimal duct obstruction due to radioiodine therapy were analyzed, among them 30 cases of dacryocystorinostomy and 17 cases of recanalization of the tear ducts. In 15 cases, dacryocystorinostomy was supplemented by the formation of an anastomosis in the area of the Hasner's valve. A comparative analysis of the effectiveness of surgical intervention depending on the localization of obstruction was carried out. Results. Dacryocystorinostomy was effective in 90% of cases, recanalization of the tear ducts – in 13% of cases. The analysis revealed that in cases of obstruction at the level of the lacrimal sac, the success of dacryocystorinostomy was 100% (5 observations), with obstruction at the level of the middle part of the nasolacrimal duct – 85.7% (12 observations), with obstruction at the level of the Hasner's valve – 100% (6 observations). Recanalization of the tear ducts was characterized by success in 100% of cases (1 observation) with obstruction of the middle part of the nasolacrimal duct and in 6.3% of cases (1 observation) with obstruction at the level of Hasner's valve. Conclusion. Dacryocystorinostomy is an effective intervention in patients with secondary acquired nasolacrimal duct obstruction due to radioiodine therapy. Recanalization of the tear ducts is characterized by low efficiency. The analysis of the effectiveness of these interventions, considering the localization of obstruction of the tear ducts, showed that the effectiveness of surgical treatment may vary depending on the level of obstruction. In cases of anatomically low obstruction of the tear ducts, dacryocystorinostomy was supplemented by the formation of an anastomosis in the area of the Hasner's valve. Recanalization of the tear ducts was characterized by greater efficiency in cases where the level of obstruction of the tear ducts was higher than the Hasner's valve than directly at Hasner's valve. The choice of treatment tactics for patients with secondary acquired nasolacrimal duct obstruction due to radioiodine therapy should be differentiated depending on the localization of the tear duct obstruction. Key words: tear ducts, radioiodine, dacryocystorhinostomy, nasolacrimal duct intubation
{"title":"Analysis of surgical interventions outcomes in patients with nasolacrimal duct obliteration due to radioiodine therapy","authors":"V. Yartsev, E. L. At’kova","doi":"10.25276/0235-4160-2023-1-69-75","DOIUrl":"https://doi.org/10.25276/0235-4160-2023-1-69-75","url":null,"abstract":"Relevance. Nasolacrimal duct obstruction occurs in 9% of patients after radioiodine therapy for thyroid cancer. The surgical interventions used in this case have not been studied enough; indications for certain operations have not been developed. Purpose. To evaluate clinical efficacy of surgical treatment in patients with nasolacrimal duct obstruction due to radioactive iodine therapy. Material and methods. The outcomes of 47 surgeries in patients with secondary acquired nasolacrimal duct obstruction due to radioiodine therapy were analyzed, among them 30 cases of dacryocystorinostomy and 17 cases of recanalization of the tear ducts. In 15 cases, dacryocystorinostomy was supplemented by the formation of an anastomosis in the area of the Hasner's valve. A comparative analysis of the effectiveness of surgical intervention depending on the localization of obstruction was carried out. Results. Dacryocystorinostomy was effective in 90% of cases, recanalization of the tear ducts – in 13% of cases. The analysis revealed that in cases of obstruction at the level of the lacrimal sac, the success of dacryocystorinostomy was 100% (5 observations), with obstruction at the level of the middle part of the nasolacrimal duct – 85.7% (12 observations), with obstruction at the level of the Hasner's valve – 100% (6 observations). Recanalization of the tear ducts was characterized by success in 100% of cases (1 observation) with obstruction of the middle part of the nasolacrimal duct and in 6.3% of cases (1 observation) with obstruction at the level of Hasner's valve. Conclusion. Dacryocystorinostomy is an effective intervention in patients with secondary acquired nasolacrimal duct obstruction due to radioiodine therapy. Recanalization of the tear ducts is characterized by low efficiency. The analysis of the effectiveness of these interventions, considering the localization of obstruction of the tear ducts, showed that the effectiveness of surgical treatment may vary depending on the level of obstruction. In cases of anatomically low obstruction of the tear ducts, dacryocystorinostomy was supplemented by the formation of an anastomosis in the area of the Hasner's valve. Recanalization of the tear ducts was characterized by greater efficiency in cases where the level of obstruction of the tear ducts was higher than the Hasner's valve than directly at Hasner's valve. The choice of treatment tactics for patients with secondary acquired nasolacrimal duct obstruction due to radioiodine therapy should be differentiated depending on the localization of the tear duct obstruction. Key words: tear ducts, radioiodine, dacryocystorhinostomy, nasolacrimal duct intubation","PeriodicalId":424200,"journal":{"name":"Fyodorov journal of ophthalmic surgery","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114699713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-29DOI: 10.25276/0235-4160-2023-1-37-46
V. D. Antonuk, T. S. Kuznetsova, O. Kuranova, S.Y. Shchukin
Purpose. To evaluate state of the blood flow parameters of the macular region, the optic nerve disc, and the state of the premacular bag after the formation of the corneal lenticle during the correction of myopia using CLEAR technology. Material and methods. From December 2021 to February 2022, 25 patients (44 eyes) aged 18 to 39 years (31.88±1.15, M±m) with myopia (–4.08±0.19, M±m) and myopic astigmatism (–0.47±0.04, M±m), who underwent femtolaser lenticular vision correction using CLEAR technology. As additional examination methods, all patients underwent optical coherence tomography on the Nidek RS-3000 Advance AngioScan device (NIDEK, Japan) in order to evaluate the following parameters: vascular network density and blood flow index in the macular region of the retina and optic disc before surgery and 1 day after the CLEAR correction, as well as to determine the size of the premacular bag before surgery and 1 day later. Results. In patients after performing vision correction using CLEAR technology, there are no statistically significant changes in the vascular network density and blood flow index in the macular region of the retina and in the optic disc, as well as the size of the premacular bag 1 day after surgery. Conclusion. With femtolaser lenticular correction of myopia, a longer vacuum effect on the eye is provided at the stage of corneal lenticular formation. However, this does not affect the condition of the blood flow of the posterior segment of the eye in the first day after surgery. Key words: femtolaser correction, lenticula, myopia, vacuum exposure, vascular network density, blood flow index, macular area of the retina, Optical Nerv, premacular bag
{"title":"Evaluation of the fundus blood flow in the early postoperative period after femtolaser lenticular CLEAR technology correction of myopia using OCT-angio","authors":"V. D. Antonuk, T. S. Kuznetsova, O. Kuranova, S.Y. Shchukin","doi":"10.25276/0235-4160-2023-1-37-46","DOIUrl":"https://doi.org/10.25276/0235-4160-2023-1-37-46","url":null,"abstract":"Purpose. To evaluate state of the blood flow parameters of the macular region, the optic nerve disc, and the state of the premacular bag after the formation of the corneal lenticle during the correction of myopia using CLEAR technology. Material and methods. From December 2021 to February 2022, 25 patients (44 eyes) aged 18 to 39 years (31.88±1.15, M±m) with myopia (–4.08±0.19, M±m) and myopic astigmatism (–0.47±0.04, M±m), who underwent femtolaser lenticular vision correction using CLEAR technology. As additional examination methods, all patients underwent optical coherence tomography on the Nidek RS-3000 Advance AngioScan device (NIDEK, Japan) in order to evaluate the following parameters: vascular network density and blood flow index in the macular region of the retina and optic disc before surgery and 1 day after the CLEAR correction, as well as to determine the size of the premacular bag before surgery and 1 day later. Results. In patients after performing vision correction using CLEAR technology, there are no statistically significant changes in the vascular network density and blood flow index in the macular region of the retina and in the optic disc, as well as the size of the premacular bag 1 day after surgery. Conclusion. With femtolaser lenticular correction of myopia, a longer vacuum effect on the eye is provided at the stage of corneal lenticular formation. However, this does not affect the condition of the blood flow of the posterior segment of the eye in the first day after surgery. Key words: femtolaser correction, lenticula, myopia, vacuum exposure, vascular network density, blood flow index, macular area of the retina, Optical Nerv, premacular bag","PeriodicalId":424200,"journal":{"name":"Fyodorov journal of ophthalmic surgery","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126486116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-17DOI: 10.25276/0235-4160-2022-4s-85-91
A. Krasov, N.N. Lansere, I.I. Fadeev, A. Gelfand, M.V. Lesnevskii
Relevance. According to the law « the security of critical information infrastructure of the Russian Federation» 26.07.2017 No. 187-FZ information systems used in ophthalmology can be classified as significant objects of critical information infrastructure if a targeted computer attack can cause serious damage (assessed by five significance indicators). The study considers common objects of critical information infrastructure in the healthcare sector, analyzes typical ophthalmic automated control systems, assesses actual offenders for these systems and the consequences of the implementation of information security threats by them, based on which refined criteria are developed for classifying objects as significant. Purpose. Analysis of typical processes of information systems in the field of ophthalmology. Justification of the choice of systems belonging to the category of «critical». Material and methods. Common objects of critical information infrastructure in automated control systems is carried out. Results. An assessment of actual violators for information systems in the field of ophthalmology was carried out. The consequences of security breaches are identified, based on which refined criteria are developed for classifying objects as significant. Conclusion. The first step in the categorization process is to determine the list of objects (information systems) that are most critical in terms of the consequences of computer attacks for the functioning of a critical infrastructure subject. Not all enterprise information systems provide critical information processes and have signs of a significance category. Keywords: critical information infrastructure, healthcare sector, ophthalmology, information security threats, intruder model, categorization criteria
{"title":"Typical ophthalmic critical information systems","authors":"A. Krasov, N.N. Lansere, I.I. Fadeev, A. Gelfand, M.V. Lesnevskii","doi":"10.25276/0235-4160-2022-4s-85-91","DOIUrl":"https://doi.org/10.25276/0235-4160-2022-4s-85-91","url":null,"abstract":"Relevance. According to the law « the security of critical information infrastructure of the Russian Federation» 26.07.2017 No. 187-FZ information systems used in ophthalmology can be classified as significant objects of critical information infrastructure if a targeted computer attack can cause serious damage (assessed by five significance indicators). The study considers common objects of critical information infrastructure in the healthcare sector, analyzes typical ophthalmic automated control systems, assesses actual offenders for these systems and the consequences of the implementation of information security threats by them, based on which refined criteria are developed for classifying objects as significant. Purpose. Analysis of typical processes of information systems in the field of ophthalmology. Justification of the choice of systems belonging to the category of «critical». Material and methods. Common objects of critical information infrastructure in automated control systems is carried out. Results. An assessment of actual violators for information systems in the field of ophthalmology was carried out. The consequences of security breaches are identified, based on which refined criteria are developed for classifying objects as significant. Conclusion. The first step in the categorization process is to determine the list of objects (information systems) that are most critical in terms of the consequences of computer attacks for the functioning of a critical infrastructure subject. Not all enterprise information systems provide critical information processes and have signs of a significance category. Keywords: critical information infrastructure, healthcare sector, ophthalmology, information security threats, intruder model, categorization criteria","PeriodicalId":424200,"journal":{"name":"Fyodorov journal of ophthalmic surgery","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126622732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-17DOI: 10.25276/0235-4160-2022-4s-108-114
I.A. Ushakov, R.I. Dementiev, D.Y. Derzhko
Relevance. Currently, to ensure secure data transmission in geographically distributed information systems, including in ophthalmology, in particular secure data transmission of telemedicine consultations, when exchanging data between various healthcare institutions, when transmitting data during multicenter clinical trials, scientific developments, Multipoint Private Network (DMVPN) technology is widely used. DMVPN allows you to significantly reduce the load on equipment when organizing the work of remote offices. This «overlay» VPN reduces the participation of the provider in organizing a connection with a large number of users compared to analogues of the «peer-to-peer» type. Purpose. To evaluate the features of the transition to Eltex equipment when building a DMVPN in geographically distributed information systems in ophthalmology. Material and methods. Eltex ESR-200 routers were used as a laboratory stand. To measure the throughput of routers, the Iperf3 software product was used – a cross-platform console client-server program. Results. This article provides an assessment of the throughput of Eltex equipment when building secure DMVPN tunnels. Conclusion. Eltex equipment is productive and effective for solving the problems of building secure DMVPN tunnels to ensure secure data transmission in geographically distributed information systems in ophthalmology. Keywords: information security, performance, fault tolerance, DMVPN, IPsec, NHRP, routing, GRE tunnels
{"title":"Secure data transmission in geographically distributed information systems in ophthalmology based on domestic equipment","authors":"I.A. Ushakov, R.I. Dementiev, D.Y. Derzhko","doi":"10.25276/0235-4160-2022-4s-108-114","DOIUrl":"https://doi.org/10.25276/0235-4160-2022-4s-108-114","url":null,"abstract":"Relevance. Currently, to ensure secure data transmission in geographically distributed information systems, including in ophthalmology, in particular secure data transmission of telemedicine consultations, when exchanging data between various healthcare institutions, when transmitting data during multicenter clinical trials, scientific developments, Multipoint Private Network (DMVPN) technology is widely used. DMVPN allows you to significantly reduce the load on equipment when organizing the work of remote offices. This «overlay» VPN reduces the participation of the provider in organizing a connection with a large number of users compared to analogues of the «peer-to-peer» type. Purpose. To evaluate the features of the transition to Eltex equipment when building a DMVPN in geographically distributed information systems in ophthalmology. Material and methods. Eltex ESR-200 routers were used as a laboratory stand. To measure the throughput of routers, the Iperf3 software product was used – a cross-platform console client-server program. Results. This article provides an assessment of the throughput of Eltex equipment when building secure DMVPN tunnels. Conclusion. Eltex equipment is productive and effective for solving the problems of building secure DMVPN tunnels to ensure secure data transmission in geographically distributed information systems in ophthalmology. Keywords: information security, performance, fault tolerance, DMVPN, IPsec, NHRP, routing, GRE tunnels","PeriodicalId":424200,"journal":{"name":"Fyodorov journal of ophthalmic surgery","volume":"452 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122575383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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