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Preeclampsia prediction model using the dipstick test for proteinuria during early gestation 妊娠早期蛋白尿试纸试验预测先兆子痫模型
IF 0.2 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2021-09-15 DOI: 10.21203/rs.3.rs-887730/v1
H. Ohseto, M. Ishikuro, T. Obara, K. Murakami, T. Onuma, A. Noda, F. Ueno, N. Iwama, M. Kikuya, H. Metoki, J. Sugawara, S. Kuriyama
ObjectiveThe aim of our study was to develop prediction model for preeclampsia (PE) using routinely examined items in early pregnancy especially dipstick test for proteinuria.MethodThe Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study recruited pregnant women and we included 9,086 of them in analysis. Maternal basic characteristics were obtained by self-report, and blood pressure and dipstick test of proteinuria were obtained by medical record at regular antenatal care. The outcome was defined as PE including superimposed preeclampsia. We developed prediction model without dipstick test of proteinuria (model 1) and model with it (model 2), and we compared them by the mean of area under the receiver operating characteristic curve (mAUROC) using five-fold cross validation.ResultsmAUROC of model 1 was 0.769 (95% CI; 0.741 to 0.797) and that of model 2 was 0.785 (95% CI; 0.758 to 0.812). The difference of two mAUROCs was 0.016 (95% CI; 0.004 to 0.028). In model 2, detection rates at false-positive rate of 5%, 10% and 20% were 40%, 49% and 64%, respectively.ConclusionsWe could develop prediction model for PE using routine antenatal care items and it was improved by including dipstick test for proteinuria.
本研究的目的是利用妊娠早期的常规检查项目,特别是蛋白尿试纸测试,建立先兆子痫(PE)的预测模型。方法东北医疗大银行计划生育和三代队列研究招募孕妇,我们将9086名孕妇纳入分析。母亲的基本特征通过自我报告获得,血压和蛋白尿试纸测试通过定期产前护理的病历获得。结果被定义为PE,包括叠加先兆子痫。我们开发了无蛋白尿试纸测试的预测模型(模型1)和有蛋白尿试纸的模型(模型2),并使用五倍交叉验证通过受试者工作特征曲线下面积的平均值(mAUROC)对它们进行了比较。结果模型1的mAUROC为0.769(95%CI;0.741至0.797),模型2的mAUROC=0.785(95%CI:0.758至0.812),两种mAUROC的差异为0.016(95%CI,0.004至0.028),模型2中假阳性率分别为5%、10%和20%的检出率分别为40%、49%和64%。结论我们可以利用常规的产前护理项目建立PE的预测模型,并通过包括蛋白尿试纸测试来改进该模型。
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引用次数: 1
Influence of second stage of labor duration on umbilical artery lactate levels in uncomplicated multiparous women 第二产程对无并发症多胎妇女脐动脉乳酸水平的影响
IF 0.2 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2021-08-31 DOI: 10.14390/jsshp.hrp2021-008
R. Kurashina, Y. Kuwabara, T. Takeshita, Shunji Suzuki
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引用次数: 0
Placenta accreta after cesarean section with a transverse fundal uterine incision 子宫底横切口剖宫产术后植入胎盘
IF 0.2 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2021-08-31 DOI: 10.14390/JSSHP.HRP2020-020
Ryuta Miyake, Y. Takeda, M. Ichikawa, Juria Akasaka, S. Maruyama, K. Naruse
The transverse fundal uterine incision (TFUI), a new cesarean section technique, is effective in cases of abnormal placentation which may cause massive hemorrhage. A 43-year-old multipara woman underwent TFUI cesarean section after being diagnosed with placenta previa. One year and 4 months later, she conceived naturally. The placenta was located on the previous cesarean section scar, and placenta percreta was suspected on magnetic resonance imaging. At 35 weeks and 2 days of gestation, cesarean delivery was performed. After a decision was made not to remove the placenta, total hysterectomy was performed, and bleeding was successfully controlled. Histopathological analysis of the uterus revealed placenta accreta. Although TFUI is a useful cesarean section method, the risk of placenta accreta may increase in the next pregnancy, requiring careful perinatal management.
子宫底横切口(TFUI)是一种新的剖宫产术,在胎盘形成异常可能导致大出血的情况下是有效的。一位43岁的经产妇在被诊断为前置胎盘后接受了TFUI剖宫产术。一年零四个月后,她自然受孕。胎盘位于之前的剖宫产疤痕上,磁共振成像怀疑为percreta胎盘。在妊娠35周零2天时,进行剖宫产。在决定不切除胎盘后,进行了全子宫切除术,并成功控制了出血。子宫组织病理学分析显示胎盘植入。尽管TFUI是一种有用的剖宫产方法,但在下一次怀孕时,胎盘植入的风险可能会增加,需要谨慎的围产期管理。
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引用次数: 0
Third trimester fetal death in heterotopic cervical pregnancy: a case report and literature review 异位子宫颈妊娠晚期胎儿死亡1例并文献复习
IF 0.2 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2021-05-31 DOI: 10.14390/JSSHP.HRP2020-021
Naohiro Suzuki, Yoshitsugu Chigusa, S. Minamiguchi, Ayami Ishida, A. Horie, Masaki Mandai, E. Kondoh
Few reports have described the impact of chemical pregnancy on a viable fetus in heterotopic cervical pregnancy. A 38-year-old primigravida was transferred to our hospital with severe abdominal pain at 32 weeks of gestation. She was tentatively diagnosed with placental abruption with intrauterine fetal death (IUFD), and a stillborn fetus was delivered vaginally. Massive vaginal bleeding continued during labor and was uncontrolled after delivery, requiring a hysterectomy. Macroscopic examination revealed a solid nodule in the uterine cervix. Histologically, the nodule consisted of villous tissue. Fluorescent in situ hybridization revealed two placental tissues derived from different embryos, indicating heterotopic cervical pregnancy. Although pregnancy was achieved after double embryo transfer, no early ultrasound findings suggested cervical pregnancy. This is the first report of heterotopic cervical pregnancy in which retained products after a chemical pregnancy caused sudden massive hemorrhage and IUFD in the third trimester.
很少有报道描述化学妊娠对异位子宫颈妊娠存活胎儿的影响。一位38岁的初产妇在妊娠32周因严重腹痛转至我院。初步诊断为胎盘早剥合并宫内死胎(IUFD),经阴道分娩为死胎。大量阴道出血在分娩过程中持续,分娩后无法控制,需要子宫切除术。肉眼检查发现子宫颈有一实性结节。组织学上,结节由绒毛组织组成。荧光原位杂交显示来自不同胚胎的两个胎盘组织,提示宫颈异位妊娠。虽然双胚胎移植后妊娠成功,但早期超声检查未发现宫颈妊娠。这是首次报道异位子宫颈妊娠,化学妊娠后残留产品导致妊娠晚期突然大出血和IUFD。
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引用次数: 0
A survey on the measurement of blood pressure in pregnant women and management of hypertensive disorders of pregnancy by the Japan Society for the Study of Hypertension in Pregnancy (JSSHP) 日本妊娠高血压研究学会(JSSHP)对孕妇血压测量和妊娠高血压疾病管理的调查
IF 0.2 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2021-01-21 DOI: 10.14390/JSSHP.HRP2020-013
Hirotada Suzuki, K. Takagi, Kanji Tanaka, A. Ichihara, H. Seki
Aim: A questionnaire survey was conducted by the scientific committee of the Japan Society for the Study of Hypertension in Pregnancy (JSSHP) to clarify whether the measurement of blood pressure in pregnant women and management of hypertensive disorders of pregnancy differ between obstetricians. Methods: We distributed anonymous questionnaires to 624 members of the JSSHP by mail in May 2019. Results: Valid responses were obtained from 206 obstetricians. The majority of obstetricians used an automatic sphygmomanometer to screen for hypertension in clinical settings. Home blood pressure measurements were used by 97% of obstetricians to diagnose white coat hypertension. However, blood pressure measurements performed by many obstetricians in clinical and non-clinical settings did not comply with standards for non-pregnant adults. Furthermore, blood pressure goals in women with hypertensive disorders of pregnancy varied among obstetricians. Conclusions: In Japan, an automatic sphygmomanometer in clinical settings and home blood pressure measurements in non-clinical settings are commonly used in practice for pregnant women. However, obstetricians may need to be re-educated on how to perform correct blood pressure measurements in these settings. Further evidence is needed to establish appropriate blood pressure goals in pregnant women with hypertensive disorders of pregnancy.
目的:日本妊娠期高血压研究学会(JSSHP)科学委员会进行了一项问卷调查,以澄清产科医生在孕妇血压测量和妊娠期高血压疾病管理方面是否存在差异。方法:于2019年5月向JSSHP 624名会员邮寄匿名问卷。结果:获得206名产科医生的有效反馈。大多数产科医生在临床环境中使用自动血压计来筛查高血压。97%的产科医生使用家庭血压测量来诊断白大褂高血压。然而,许多产科医生在临床和非临床环境中进行的血压测量不符合非怀孕成人的标准。此外,产科医生对妊娠期高血压疾病妇女的血压目标也各不相同。结论:在日本,临床环境中的自动血压计和非临床环境中的家庭血压测量在孕妇实践中普遍使用。然而,产科医生可能需要接受再教育,了解如何在这些情况下进行正确的血压测量。需要进一步的证据来确定妊娠期高血压疾病孕妇适当的血压目标。
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引用次数: 1
Trends in mode of breech delivery in Japan 日本臀位分娩方式的发展趋势
IF 0.2 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2021-01-15 DOI: 10.14390/JSSHP.HRP2020-017
K. Sagawa, Shunji Suzuki, S. Takeda, K. Kinoshita
Many facilities in Japan currently perform elective cesarean section for term singleton breech presentation, and young doctors training in obstetrics and gynecology may not have had a chance to experience vaginal breech delivery. However, vaginal breech delivery remains an option if comprehensive informed consent is obtained. To reduce the incidence of nuchal arm, “transverse figure 8 breech delivery (TF8 maneuver)” has been widely recommended in Japan. This review discusses trends in mode of breech delivery in Japan, with a focus on the TF8 maneuver.
目前,日本的许多机构都在为足月单胎剖宫产进行选择性剖宫产手术,而接受过妇产科培训的年轻医生可能没有机会经历阴道臀位分娩。然而,如果获得全面的知情同意,阴道臀位分娩仍然是一种选择。为了减少颈臂的发生率,“横贯8字形臀位分娩(TF8手法)”在日本被广泛推荐。这篇综述讨论了日本后臀交付模式的趋势,重点是TF8机动。
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引用次数: 1
Preventive measures against the spread of nosocomial COVID-19 infection: a report of experiences in an obstetric facility at a regional hospital in Japan 预防院内COVID-19感染传播的措施:日本一家地区医院产科设施的经验报告
IF 0.2 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2021-01-01 DOI: 10.14390/JSSHP.HRP2020-016
H. Shinagawa, Ryosei Shikano, A. Takagi, K. Kuromaki
We describe the emergency measures taken in response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in an obstetrics ward in Japan. In April 2020, two midwives in our obstetric ward were diagnosed with SARS-CoV-2 infection. We immediately closed the ward and performed polymerase chain reaction (PCR) testing for 25 patients and 42 staff members who had possible contact with the midwives. Pregnant women at or near term were referred to nearby obstetric facilities. One patient, who delivered before the midwives were diagnosed, and her neonate tested positive for SARS-CoV-2. All other tested patients and staff had negative PCR test results. In total, 14 pregnant women at term and 15 at 34–36 weeks gestation were referred to other facilities. Of these, 13 delivered in transfer destinations and 16 delivered in our hospital after a 14-day temporary closure of the ward. Our prompt measures successfully prevented the nosocomial spread of coronavirus disease.
我们描述了在日本产科病房应对严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)感染所采取的紧急措施。2020年4月,我们产科病房的两名助产士被诊断出感染了SARS-CoV-2。我们立即关闭病房,对25名患者和42名可能与助产士有接触的工作人员进行了聚合酶链反应(PCR)检测。怀孕或接近足月的妇女被转诊到附近的产科设施。一名患者在助产士被诊断出来之前分娩,她的新生儿检测出SARS-CoV-2阳性。其他接受检测的患者和工作人员PCR检测结果均为阴性。总共有14名足月孕妇和15名妊娠34-36周的孕妇被转介到其他机构。其中,13例在转院目的地分娩,16例在病房临时关闭14天后在我院分娩。我们及时采取措施,成功防止了冠状病毒病的院内传播。
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引用次数: 0
Gasless laparoscopic ovarian cystectomy for pregnant women 孕妇无气腹腹腔镜卵巢囊肿切除术
IF 0.2 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2021-01-01 DOI: 10.14390/jsshp.hrp2021-015
R. Kurashina, S. Akira, H. Kaseki, Shunji Suzuki
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引用次数: 0
Postpartum Mental Status in Women with Social Problems at a Japanese perinatal center 日本围产期中心社会问题妇女的产后精神状况
IF 0.2 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2021-01-01 DOI: 10.14390/jsshp.hrp2021-011
R. Kurashina, Shunji Suzuki
We examined the association between ‘specified expectant mothers (SEMs; pregnant women with social problems)’ at our institute and their mental status at one month after delivery. We examined 890 pregnant women who delivered at ≥ 37 weeks of gestation at our institute between January 2019 and October 2019. We excluded mothers with mental disorders requiring medication and whose children were hospitalized in the neonatal intensive care unit. During the study period, there were 148 SEMs with healthy babies (16.6%). The frequency of screening positive on the Japanese version of the Mother-to-Infant Bonding Scale and the Edinburgh Postnatal Depression Scale was higher in SEMs than in non-SEMs (P = 0.04 and 0.02). In addition, there was a strong positive correlation between scores on the two scales in SEMs (r2 = 0.41, P < 0.01). The present results indicate the quantitatively clarify of the mental vulnerabilities in SEMs.
我们研究了特定准妈妈(SEMs);有社会问题的孕妇和产后一个月的精神状况。我们检查了2019年1月至2019年10月期间在我们研究所分娩的890名妊娠≥37周的孕妇。我们排除了需要药物治疗的有精神障碍且其孩子在新生儿重症监护病房住院的母亲。在研究期间,有148名有健康婴儿的sem(16.6%)。日本版《母婴依恋量表》和《爱丁堡产后抑郁量表》筛选阳性的频率在中小企业组高于非中小企业组(P = 0.04和0.02)。此外,两种量表的SEMs得分之间存在较强的正相关(r2 = 0.41, P < 0.01)。本研究结果为中小企业心理脆弱性的定量研究提供了依据。
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引用次数: 1
Opportunistic salpingectomy at cesarean delivery in Japan: A questionnaire for registered physicians of the MFICU Liaison Council 日本剖宫产的机会性输卵管切除术:MFICU联络委员会注册医生的问卷调查
IF 0.2 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2021-01-01 DOI: 10.14390/jsshp.hrp2021-007
Hirotada Suzuki, A. Ohkuchi, K. Horie, S. Nagayama, M. Ogoyama, R. Usui, Hironori Takahashi, Hiroyuki Fujiwara
Aim: A questionnaire survey was conducted to establish whether opportunistic salpingectomy has been performed at cesarean delivery or is intended in the future and also to clarify the steps taken to achieve the goal of performing opportunistic salpingectomy at cesarean delivery in Japan. Methods: We distributed anonymous questionnaires on opportunistic salpingectomy at cesarean delivery to registered physicians of the Maternal Fetal Intensive Care Unit Liaison Council of Japan using a mailing list in 2019. Answer sheets were returned by fax with an unscripted name. Results: Valid responses were obtained from 68 physicians; 28% ( n = 19/68) performed opportunistic salpingectomy at cesarean delivery, while 16% ( n = 8/49) hoped to conduct opportunistic salpingectomy in the future. Most of the physicians performing opportunistic salpingectomy (74%: n = 14/19) had conducted salpingectomy as one of the permanent surgical contraception procedures provided for by law without the approval of an Ethics Committee. Conclusions: Opportunistic salpingectomy at cesarean delivery to reduce the risk of ovarian, fallopian tube, and peritoneal carcinoma in patients at average risk has not yet been widely practiced in Japan. Approximately 25% of physicians have performed opportunistic salpingectomy, 75% of whom conducted this procedure instead of tubal ligation for pregnant women who requested sterilization at cesarean delivery.
目的:通过问卷调查,了解日本剖宫产手术中是否已经实施了机会性输卵管切除术或将来是否打算实施机会性输卵管切除术,并明确为实现日本剖宫产手术中实施机会性输卵管切除术的目标所采取的措施。方法:采用邮寄列表方式,于2019年向日本母婴重症监护病房联络委员会注册医师发放关于剖宫产机会性输卵管切除术的匿名问卷。答题纸是用传真寄来的,上面没有写姓名。结果:共获得68名医生的有效回复;28% (n = 19/68)的患者在剖宫产时行机会性输卵管切除术,16% (n = 8/49)的患者希望以后行机会性输卵管切除术。大多数实施机会性输卵管切除术的医生(74%:n = 14/19)在未经伦理委员会批准的情况下,将输卵管切除术作为法律规定的永久性手术避孕措施之一。结论:剖宫产时机会性输卵管切除术以降低平均风险患者发生卵巢、输卵管和腹膜癌的风险在日本尚未广泛应用。大约25%的医生做过机会性输卵管切除术,其中75%的医生对剖宫产时要求绝育的孕妇进行这种手术而不是输卵管结扎。
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引用次数: 0
期刊
Hypertension Research in Pregnancy
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