{"title":"Journal Awards for the Year 2018","authors":"","doi":"10.14390/jsshp.8.1","DOIUrl":"https://doi.org/10.14390/jsshp.8.1","url":null,"abstract":"","PeriodicalId":42505,"journal":{"name":"Hypertension Research in Pregnancy","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2020-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46399102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hiroyoshi Ko, Liangcheng Wang, Aya Ishiguro, Azusa Kimura, M. Omori, Yuko Irie, K. Imai, K. Chikazawa, Isao Horiuchi, T. Kuwata, R. Konno, K. Takagi
Introduction: The aim of the study was to evaluate if hyperbaric area index (HBI) can be a good predictor for adverse neonatal outcome in patients with hypertensive disorder pregnancy. Method: A retrospective study enrolled 78 cases whose 24 hours ambulatory blood pressure monitoring (ABPM) was measured before delivery was performed. Patients were divided into two groups by the timing of measurement after 20 gestational weeks or not. HBI scores that obtained by integral calculator of the difference between the measured blood pressure and base line to time axis were calculated. Neonatal outcomes including gestational week at birth and infant weight were evaluated. The ROC curve was used to determine the association between scores and neonatal outcomes. Result: Of 78 women, 33 were measured less than 20 weeks and 45 were measure after 20 weeks. The mean gestational weeks at delivery was 36 ± 2.2 weeks, and the mean birth weight was 2,540 ± 590 g. When the blood pressure baseline was set as 140 mmHg, the cutoff value of the score is 43.5 mmHg-hour (AUC is 0.741), and the odds ratio of birth weight < 2,000 g is 8.3 (95%CI: 2.7–28.0). However, the AUCs were 0.778 in the group after 20 weeks and 0.345 in the group less than 20 weeks respectively. When the blood pressure criteria value was set to 135 mmHg, the AUC in the group less than 20 weeks increased to 0.707. Conclusion: HBI can be a useful predictor for adverse neonatal outcome in patients with hypertensive disorder pregnancy.
{"title":"Committee for Academic Affairs JSSHP Research Award 2019 Clinical Research Hyperbaric area index, a novel method to predict outcome of patients with hypertension disorder pregnancy","authors":"Hiroyoshi Ko, Liangcheng Wang, Aya Ishiguro, Azusa Kimura, M. Omori, Yuko Irie, K. Imai, K. Chikazawa, Isao Horiuchi, T. Kuwata, R. Konno, K. Takagi","doi":"10.14390/jsshp.8.2","DOIUrl":"https://doi.org/10.14390/jsshp.8.2","url":null,"abstract":"Introduction: The aim of the study was to evaluate if hyperbaric area index (HBI) can be a good predictor for adverse neonatal outcome in patients with hypertensive disorder pregnancy. Method: A retrospective study enrolled 78 cases whose 24 hours ambulatory blood pressure monitoring (ABPM) was measured before delivery was performed. Patients were divided into two groups by the timing of measurement after 20 gestational weeks or not. HBI scores that obtained by integral calculator of the difference between the measured blood pressure and base line to time axis were calculated. Neonatal outcomes including gestational week at birth and infant weight were evaluated. The ROC curve was used to determine the association between scores and neonatal outcomes. Result: Of 78 women, 33 were measured less than 20 weeks and 45 were measure after 20 weeks. The mean gestational weeks at delivery was 36 ± 2.2 weeks, and the mean birth weight was 2,540 ± 590 g. When the blood pressure baseline was set as 140 mmHg, the cutoff value of the score is 43.5 mmHg-hour (AUC is 0.741), and the odds ratio of birth weight < 2,000 g is 8.3 (95%CI: 2.7–28.0). However, the AUCs were 0.778 in the group after 20 weeks and 0.345 in the group less than 20 weeks respectively. When the blood pressure criteria value was set to 135 mmHg, the AUC in the group less than 20 weeks increased to 0.707. Conclusion: HBI can be a useful predictor for adverse neonatal outcome in patients with hypertensive disorder pregnancy.","PeriodicalId":42505,"journal":{"name":"Hypertension Research in Pregnancy","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2020-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45024410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: Administration of angiotensin II receptor blocker (ARB) to pregnant women is contraindicated due to the risk of inducing oligohydramnios. However, it is unclear if the ARBs on the market uniformly induce oligohydramnios. The aim of this study was to find an ARB that is less likely to develop oligohydramnios based on the frequency of side effects registered in the US Food and Drug Administration Adverse Event Reporting System (FAERS) and to show the mechanism of the lower risk of developing oligohydramnios in non-clinical studies. Methods: We searched for cases registered in FAERS from 2004 to 2017, investigated the frequency of adverse event records of patients taking ARB showing oligohydramnios, and compared them among ARB drugs. We compared the antihypertensive effect of the selected ARBs and their fetal transfer in the model rats of hypertensive disorder of pregnancy with administration of L-NAME, a nonselective nitric oxide synthase inhibitor. The transport activity of organic anion transporting polypeptide (OATP) 2B1 was evaluated by using HEK293 cells transiently transfected with cDNA of human OATP2B1. The drug concentrations were measured by liquid chromatography with tandem mass spectrometry. Results: Of the 6 ARBs investigated, olmesartan had the highest frequency of oligohydramnios, and irbesartan had the lowest frequency, with a 25-fold difference in reporting frequency. In pregnant hypertensive rats, both olmesartan and irbesartan showed remarkable antihypertensive effect, while only irbesartan showed the effect of improving fetal growth failure. Ratio of the plasma concentration in the fetus to that in the dam (F/M ratio)
{"title":"Committee for Academic Affairs JSSHP Research Award 2019 Basic Research Screening of an Angiotensin II Receptor Blocker with Low Adverse Fetal Effect using Adverse Event Reporting System and Mechanism of the Low Placental Transfer","authors":"T. Nishimura, Y. Ishikawa, S. Noguchi, M. Tomi","doi":"10.14390/jsshp.8.3","DOIUrl":"https://doi.org/10.14390/jsshp.8.3","url":null,"abstract":"Objective: Administration of angiotensin II receptor blocker (ARB) to pregnant women is contraindicated due to the risk of inducing oligohydramnios. However, it is unclear if the ARBs on the market uniformly induce oligohydramnios. The aim of this study was to find an ARB that is less likely to develop oligohydramnios based on the frequency of side effects registered in the US Food and Drug Administration Adverse Event Reporting System (FAERS) and to show the mechanism of the lower risk of developing oligohydramnios in non-clinical studies. Methods: We searched for cases registered in FAERS from 2004 to 2017, investigated the frequency of adverse event records of patients taking ARB showing oligohydramnios, and compared them among ARB drugs. We compared the antihypertensive effect of the selected ARBs and their fetal transfer in the model rats of hypertensive disorder of pregnancy with administration of L-NAME, a nonselective nitric oxide synthase inhibitor. The transport activity of organic anion transporting polypeptide (OATP) 2B1 was evaluated by using HEK293 cells transiently transfected with cDNA of human OATP2B1. The drug concentrations were measured by liquid chromatography with tandem mass spectrometry. Results: Of the 6 ARBs investigated, olmesartan had the highest frequency of oligohydramnios, and irbesartan had the lowest frequency, with a 25-fold difference in reporting frequency. In pregnant hypertensive rats, both olmesartan and irbesartan showed remarkable antihypertensive effect, while only irbesartan showed the effect of improving fetal growth failure. Ratio of the plasma concentration in the fetus to that in the dam (F/M ratio)","PeriodicalId":42505,"journal":{"name":"Hypertension Research in Pregnancy","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2020-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46937930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-30DOI: 10.14390/jsshp.hrp2019-018
K. Hashii, Yoshihiro Yamahata, Takao Suzuki
The Japan Council for Implementation of the Maternal Emergency Life Support System (J-CIMELS) adopted the “Kyoto protocol”—which the Kyoto Society for Emergency Response in Obstetrics and Gynecology proposed in 2010—as the “evaluation and care protocol” intended to prevent the progression of pathologic conditions in expectant and nursing mothers by detecting maternal emergencies at an early stage and by taking appropriate and required measures. The protocol also incorporates maternal care including obstetric cardiopulmonary resuscitation (CPR) in the event that pathologic conditions deteriorate further despite the measures taken. The J-CIMELS aims to popularize the protocol among medical professionals involved in perinatal care. The protocol sets forth procedures that the first detector at any obstetric institution should follow. Specifically, the protocol describes monitoring the patient’s vital signs to assess breathing, circulation, and level of consciousness, recommends simple, appropriate approaches for oxygenation and transfusion that are indispensable in maternal emergencies, and provides steps to be taken for immediate measures and the use of an automated external defibrillator and adrenaline in obstetric CPR. The J-CIMELS developed a basic simulation-based practical training course, in which trainees carry out the required measures as per the protocol through simulated maternal emergencies, and has held the course throughout Japan since 2015. Popularization of the protocol is expected to reduce the number of maternal deaths in Japan.
{"title":"Evaluation and care protocol for maternal emergencies: the basic J-CIMELS protocol derived from the Kyoto protocol","authors":"K. Hashii, Yoshihiro Yamahata, Takao Suzuki","doi":"10.14390/jsshp.hrp2019-018","DOIUrl":"https://doi.org/10.14390/jsshp.hrp2019-018","url":null,"abstract":"The Japan Council for Implementation of the Maternal Emergency Life Support System (J-CIMELS) adopted the “Kyoto protocol”—which the Kyoto Society for Emergency Response in Obstetrics and Gynecology proposed in 2010—as the “evaluation and care protocol” intended to prevent the progression of pathologic conditions in expectant and nursing mothers by detecting maternal emergencies at an early stage and by taking appropriate and required measures. The protocol also incorporates maternal care including obstetric cardiopulmonary resuscitation (CPR) in the event that pathologic conditions deteriorate further despite the measures taken. The J-CIMELS aims to popularize the protocol among medical professionals involved in perinatal care. The protocol sets forth procedures that the first detector at any obstetric institution should follow. Specifically, the protocol describes monitoring the patient’s vital signs to assess breathing, circulation, and level of consciousness, recommends simple, appropriate approaches for oxygenation and transfusion that are indispensable in maternal emergencies, and provides steps to be taken for immediate measures and the use of an automated external defibrillator and adrenaline in obstetric CPR. The J-CIMELS developed a basic simulation-based practical training course, in which trainees carry out the required measures as per the protocol through simulated maternal emergencies, and has held the course throughout Japan since 2015. Popularization of the protocol is expected to reduce the number of maternal deaths in Japan.","PeriodicalId":42505,"journal":{"name":"Hypertension Research in Pregnancy","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2020-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49139396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-30DOI: 10.14390/jsshp.hrp2019-014
Akihiko Ueda, Baku Nakakita, Yoshitsugu Chigusa, Haruta Mogami, Asako Inohaya, K. Yamaguchi, A. Horie, J. Hamanishi, M. Mandai, E. Kondoh
Objectives: To clarify the effects of tight blood pressure control on pregnancy outcomes. Methods: This retrospective study included 38 cases of singleton pregnancies which were diagnosed with essential hypertension either before pregnancy or during the first trimester of pregnancy. Patients were subdivided according to systolic blood pressure ( < 130 mmHg, 130–139 mmHg, ≥ 140 mmHg) between 8–11, 12–15, and 16–19 weeks’ gestation, respectively. The influence of systolic blood pressure in each gestational period was assessed with regard to the risk of preterm birth, foetal growth restriction, and superimposed preeclampsia. Results: At 16–19 weeks’ gestation, systolic blood pressure ≥ 140 mmHg and in the range of 130–139 mmHg was strongly linked to a shorter gestational period and lower z-scores for birth weight. The incidence of early onset superimposed preeclampsia was lower in women who had systolic blood pressure < 130 mmHg at 16–19 weeks’ gestation (11%) compared with those with a systolic blood pressure of 130–139 mmHg (27%) and ≥ 140 mmHg (75%). Conclusions: Tight control of blood pressure, with a target systolic blood pressure <
{"title":"Tight systolic blood pressure control early in pregnancy improves pregnancy outcomes in women with chronic hypertension","authors":"Akihiko Ueda, Baku Nakakita, Yoshitsugu Chigusa, Haruta Mogami, Asako Inohaya, K. Yamaguchi, A. Horie, J. Hamanishi, M. Mandai, E. Kondoh","doi":"10.14390/jsshp.hrp2019-014","DOIUrl":"https://doi.org/10.14390/jsshp.hrp2019-014","url":null,"abstract":"Objectives: To clarify the effects of tight blood pressure control on pregnancy outcomes. Methods: This retrospective study included 38 cases of singleton pregnancies which were diagnosed with essential hypertension either before pregnancy or during the first trimester of pregnancy. Patients were subdivided according to systolic blood pressure ( < 130 mmHg, 130–139 mmHg, ≥ 140 mmHg) between 8–11, 12–15, and 16–19 weeks’ gestation, respectively. The influence of systolic blood pressure in each gestational period was assessed with regard to the risk of preterm birth, foetal growth restriction, and superimposed preeclampsia. Results: At 16–19 weeks’ gestation, systolic blood pressure ≥ 140 mmHg and in the range of 130–139 mmHg was strongly linked to a shorter gestational period and lower z-scores for birth weight. The incidence of early onset superimposed preeclampsia was lower in women who had systolic blood pressure < 130 mmHg at 16–19 weeks’ gestation (11%) compared with those with a systolic blood pressure of 130–139 mmHg (27%) and ≥ 140 mmHg (75%). Conclusions: Tight control of blood pressure, with a target systolic blood pressure <","PeriodicalId":42505,"journal":{"name":"Hypertension Research in Pregnancy","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42302268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-30DOI: 10.14390/JSSHP.HRP2019-012
S. Takeda, J. Takeda, S. Makino
Laparoscopic myomectomy (LSM) is a procedure often requested by patients because of its minimal invasiveness. This procedure has, therefore, been widely performed in recent years. However, there is a need for more reports from the obstetric field to determine the effects of this procedure on subsequent pregnancies. In this regard, we searched Japanese medical literature databases for articles on Japanese cases of uterine rupture, placenta increta, or placenta percreta in pregnancy following myomectomy. This review article aims to analyze the retrieved data to clarify the issues involved and to provide useful feedback to gynecologists by sharing information with them on such issues. in pregnancy following LSM, comprising 2 full term cases (8.0%), 18 preterm cases (72.0%), and 5 abortion cases (at 7, 10, 16, 19, and 21 gestational weeks) (20.0%). There was no distinct difference between the frequencies of uterine rupture following LTM and LSM in relation to the abortion period or the preterm period. Cases of uterine rupture following LSM included 3 cases who had undergone subserous myomectomy in which electrocauterization alone was used for resection and hemostasis. In 4 cases, the submucosal myoma had been enucleated, with exposure of the endometrium. intraabdominal rupture
{"title":"Uterine rupture and placenta accreta spectrum following laparoscopic myomectomy in Japan: A message from obstetricians to gynecologic laparoscopists","authors":"S. Takeda, J. Takeda, S. Makino","doi":"10.14390/JSSHP.HRP2019-012","DOIUrl":"https://doi.org/10.14390/JSSHP.HRP2019-012","url":null,"abstract":"Laparoscopic myomectomy (LSM) is a procedure often requested by patients because of its minimal invasiveness. This procedure has, therefore, been widely performed in recent years. However, there is a need for more reports from the obstetric field to determine the effects of this procedure on subsequent pregnancies. In this regard, we searched Japanese medical literature databases for articles on Japanese cases of uterine rupture, placenta increta, or placenta percreta in pregnancy following myomectomy. This review article aims to analyze the retrieved data to clarify the issues involved and to provide useful feedback to gynecologists by sharing information with them on such issues. in pregnancy following LSM, comprising 2 full term cases (8.0%), 18 preterm cases (72.0%), and 5 abortion cases (at 7, 10, 16, 19, and 21 gestational weeks) (20.0%). There was no distinct difference between the frequencies of uterine rupture following LTM and LSM in relation to the abortion period or the preterm period. Cases of uterine rupture following LSM included 3 cases who had undergone subserous myomectomy in which electrocauterization alone was used for resection and hemostasis. In 4 cases, the submucosal myoma had been enucleated, with exposure of the endometrium. intraabdominal rupture","PeriodicalId":42505,"journal":{"name":"Hypertension Research in Pregnancy","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.14390/JSSHP.HRP2019-012","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42772157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Report of The 40th Anniversary Congress of the Japan Society for the Study of Hypertension in Pregnancy (JSSHP 2019)","authors":"","doi":"10.14390/jsshp.7.41","DOIUrl":"https://doi.org/10.14390/jsshp.7.41","url":null,"abstract":"","PeriodicalId":42505,"journal":{"name":"Hypertension Research in Pregnancy","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43008806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-30DOI: 10.14390/JSSHP.HRP2019-006
K. Takagi, Mitsue Muraoka
Aim: “En caul” cesarean section can prevent mechanical damage to preterm babies upon cesarean delivery, by intentionally not rupturing the fetal membranes. This survey investigates its prevalence, indications, and advantages and disadvantages in Japan. Methods: Questionnaires were posted to all registered Level 2 and Level 3 maternal and perinatal centers (where most premature babies are delivered) in Japan ( n = 327). Percentages of centers are presented as survey results. Results: Response rate was 53.2%. En caul cesarean section was employed in 43.2% and 81.6% of Level 2 and 3 centers, respectively. Gestational age considered for en caul cesarean section was less than 31 weeks in 75.9% of centers. Low transverse and vertical uterine incisions were made at 64% and 29% of centers, respectively. En caul cesarean section was considered useful by 87% of centers. However, nearly one-third of the respondents noted that this procedure presents some technical difficulties if membranes happen to rupture accidentally before the delivery of the fetus is complete. Conclusions: En caul cesarean section is a routine cesarean delivery technique used for preterm
{"title":"Cesarean delivery “en caul” in Japan: Results of a national survey of maternal and perinatal centers in Japan","authors":"K. Takagi, Mitsue Muraoka","doi":"10.14390/JSSHP.HRP2019-006","DOIUrl":"https://doi.org/10.14390/JSSHP.HRP2019-006","url":null,"abstract":"Aim: “En caul” cesarean section can prevent mechanical damage to preterm babies upon cesarean delivery, by intentionally not rupturing the fetal membranes. This survey investigates its prevalence, indications, and advantages and disadvantages in Japan. Methods: Questionnaires were posted to all registered Level 2 and Level 3 maternal and perinatal centers (where most premature babies are delivered) in Japan ( n = 327). Percentages of centers are presented as survey results. Results: Response rate was 53.2%. En caul cesarean section was employed in 43.2% and 81.6% of Level 2 and 3 centers, respectively. Gestational age considered for en caul cesarean section was less than 31 weeks in 75.9% of centers. Low transverse and vertical uterine incisions were made at 64% and 29% of centers, respectively. En caul cesarean section was considered useful by 87% of centers. However, nearly one-third of the respondents noted that this procedure presents some technical difficulties if membranes happen to rupture accidentally before the delivery of the fetus is complete. Conclusions: En caul cesarean section is a routine cesarean delivery technique used for preterm","PeriodicalId":42505,"journal":{"name":"Hypertension Research in Pregnancy","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43632461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-30DOI: 10.14390/jsshp.hrp2019-008
N. Natori, R. Oyama, Tsukasa Baba, C. Isurugi, H. Chida, G. Haba, Y. Sasaki, T. Kanasugi, H. Itamochi, A. Kikuchi
Aim: Velocity vector imaging (VVI) is a speckle-tracking ultrasonographic assessment technique used to evaluate myocardial function. However, VVI values show wide deviations. This study aimed to clarify the significance of serial VVI values for assessing fetal cardiac function. Methods: Echocardiographic images of 50 fetuses (normal: n = 29, fetal growth restriction [FGR]: n = 21) were obtained in the four-chamber view during the second and third trimester. VVI images were analyzed for longitudinal velocity, strain, and strain rate in the global and segmental walls of the left ventricle (LV) and right ventricle (RV). Results: Global longitudinal velocity (GLV) of the LV and RV during the third trimester did not significantly differ between FGR and normal fetuses. LVd and RVs appeared to be low in HDP cases, although there were no significant differences compared to no HDP cases. Eighty-two serial images obtained from 13 normal singleton fetuses revealed increased systolic GLV of the LV and RV, increased diastolic GLV in 10 cases, and increased longitudinal velocity in the basal and middle free wall of both the LV and RV. Conclusions: The evaluation of fetal ventricular function using VVI revealed that GLV increases throughout gestation.
{"title":"Velocity vector imaging for evaluation of fetal vertical function throughout gestation","authors":"N. Natori, R. Oyama, Tsukasa Baba, C. Isurugi, H. Chida, G. Haba, Y. Sasaki, T. Kanasugi, H. Itamochi, A. Kikuchi","doi":"10.14390/jsshp.hrp2019-008","DOIUrl":"https://doi.org/10.14390/jsshp.hrp2019-008","url":null,"abstract":"Aim: Velocity vector imaging (VVI) is a speckle-tracking ultrasonographic assessment technique used to evaluate myocardial function. However, VVI values show wide deviations. This study aimed to clarify the significance of serial VVI values for assessing fetal cardiac function. Methods: Echocardiographic images of 50 fetuses (normal: n = 29, fetal growth restriction [FGR]: n = 21) were obtained in the four-chamber view during the second and third trimester. VVI images were analyzed for longitudinal velocity, strain, and strain rate in the global and segmental walls of the left ventricle (LV) and right ventricle (RV). Results: Global longitudinal velocity (GLV) of the LV and RV during the third trimester did not significantly differ between FGR and normal fetuses. LVd and RVs appeared to be low in HDP cases, although there were no significant differences compared to no HDP cases. Eighty-two serial images obtained from 13 normal singleton fetuses revealed increased systolic GLV of the LV and RV, increased diastolic GLV in 10 cases, and increased longitudinal velocity in the basal and middle free wall of both the LV and RV. Conclusions: The evaluation of fetal ventricular function using VVI revealed that GLV increases throughout gestation.","PeriodicalId":42505,"journal":{"name":"Hypertension Research in Pregnancy","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45045298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-30DOI: 10.14390/jsshp.hrp2019-009
J. Ogawa, Shunji Suzuki
Aim: This study aimed to examine the clinical characteristics of pregnancies complicated by both fetal growth restriction (FGR) and placenta previa or low-lying placenta (PPLLP). Methods: A retrospective cohort study was performed to compare clinical characteristics of pregnancies complicated by FGR and/or PPLLP in women who do not habitually smoke or consume alcohol and who underwent delivery of singletons at ≥ 22 weeks’ gestation at Japanese Red Cross Katsushika Maternity Hospital between 2002 and 2015. Assessed factors related to patients and perinatal outcomes included maternal age, parity, history of in vitro fertilization, hypertensive disorders, delivery mode, fetal ultrasonographic findings, delivery mode, gestational age at delivery, neonatal asphyxia, and postpartum hemorrhage. Results: There were 24,118 singleton deliveries assessed for eligibility. Of these, 7 were complicated by both FGR and PPLLP. The development of FGR was not associated with the presence of PPLLP (odds ratio 1.12, 95% confidence interval 0.54–2.4, P = 0.69). Multivariate logistic regression analysis revealed that the incidence of preterm cesarean delivery due to massive bleeding in pregnancies
{"title":"Clinical characteristics of pregnancies complicated by both fetal growth restriction and placenta previa or low-lying placenta","authors":"J. Ogawa, Shunji Suzuki","doi":"10.14390/jsshp.hrp2019-009","DOIUrl":"https://doi.org/10.14390/jsshp.hrp2019-009","url":null,"abstract":"Aim: This study aimed to examine the clinical characteristics of pregnancies complicated by both fetal growth restriction (FGR) and placenta previa or low-lying placenta (PPLLP). Methods: A retrospective cohort study was performed to compare clinical characteristics of pregnancies complicated by FGR and/or PPLLP in women who do not habitually smoke or consume alcohol and who underwent delivery of singletons at ≥ 22 weeks’ gestation at Japanese Red Cross Katsushika Maternity Hospital between 2002 and 2015. Assessed factors related to patients and perinatal outcomes included maternal age, parity, history of in vitro fertilization, hypertensive disorders, delivery mode, fetal ultrasonographic findings, delivery mode, gestational age at delivery, neonatal asphyxia, and postpartum hemorrhage. Results: There were 24,118 singleton deliveries assessed for eligibility. Of these, 7 were complicated by both FGR and PPLLP. The development of FGR was not associated with the presence of PPLLP (odds ratio 1.12, 95% confidence interval 0.54–2.4, P = 0.69). Multivariate logistic regression analysis revealed that the incidence of preterm cesarean delivery due to massive bleeding in pregnancies","PeriodicalId":42505,"journal":{"name":"Hypertension Research in Pregnancy","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.14390/jsshp.hrp2019-009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44343055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：