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Simultaneous Teamwork May Improve Hypoglycemia Rates in Patients with Type 1 Diabetes Using an Insulin Pump 同时团队合作可能改善使用胰岛素泵的1型糖尿病患者的低血糖率
Pub Date : 1900-01-01 DOI: 10.25179/tjem.2021-84564
Başak ÖZGEN SAYDAM, S. C. Adiyaman, Berfu Yeşi̇lli̇, A. Bektaş, Özgül Vatansever, Nalan Aydin, Simge Ruhiye Yilmaz Kavcar, Canan Deği̇rmenci̇, F. Bayraktar, B. Akıncı
Objective: Simultaneous teamwork is an advanced collaboration subtype that includes the patient’s evaluation by the team members (including physician, nurse and dietician) together in the same session. Our study aimed to investigate the effect of a simultaneous teamwork approach on metabolic and clinical outcomes of patients with Type 1 diabetes using an insulin pump. Material and Methods: This retrospective study included 49 previous insulin pump users with Type 1 diabetes who participated in a simultaneous teamwork protocol. Metabolic and clinical parameters were collected before and after the teamwork approach. A separate analysis of 16 patients in whom insulin pump was initiated with simultaneous teamwork and pregnancy data from 9 patients were also reported. Results: Simultaneous teamwork resulted in a significant reduction in the frequency of hypoglycemic episodes in previous insulin pump users with Type 1 diabetes. Hemoglobin A1c decreased, but the difference was statistically insignificant. Simultaneous teamwork was also efficient on patients initiated an insulin pump and for pregnancy follow-up in 2 separate subsets of patients with Type 1 diabetes. Conclusion: The simultaneous teamwork approach is a practical method to manage Type 1 diabetes in insulin pump users with the potential to reduce the frequency of hypoglycemic episodes.
目的:同步团队合作是由团队成员(包括医生、护士和营养师)在同一次会议中一起对患者进行评估的高级协作亚型。我们的研究旨在探讨同时团队合作方法对使用胰岛素泵的1型糖尿病患者的代谢和临床结果的影响。材料和方法:这项回顾性研究包括49名既往使用胰岛素泵的1型糖尿病患者,他们同时参加了团队合作协议。采集团队合作治疗前后的代谢和临床参数。另一项对16例胰岛素泵治疗患者的独立分析也报道了9例患者的妊娠数据。结果:同时团队合作导致先前使用胰岛素泵的1型糖尿病患者低血糖发作频率显著降低。血红蛋白A1c降低,但差异无统计学意义。同时,团队合作在开始使用胰岛素泵的患者和2组1型糖尿病患者的妊娠随访中也很有效。结论:同时团队合作是治疗1型糖尿病胰岛素泵使用者的一种实用方法,具有降低低血糖发作频率的潜力。
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引用次数: 0
Overlapping Between Thymus Neuroendocrine Carcinoma as an Ectopic Cushing Syndrome and Exogenous Cushing’s Syndrome: A Case Report 胸腺神经内分泌癌异位库欣综合征与外源性库欣综合征重叠1例
Pub Date : 1900-01-01 DOI: 10.25179/tjem.2017-56498
E. Faraji, Sepideh Tahsini Tekantapeh
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引用次数: 2
A Bibliometric Analysis of Turkey’s Contribution to Bone Health Literature from an Endocrinologist Perspective 从内分泌学家的角度分析土耳其对骨骼健康文献的贡献
Pub Date : 1900-01-01 DOI: 10.25179/tjem.2018-62921
Ceyla Konca Değertekin, Ö. Turhan İyidir, D. Gogas Yavuz
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引用次数: 1
Case Report: Fixed Drug Eruption Caused by Dapagliflozin 达格列净致药疹1例
Pub Date : 1900-01-01 DOI: 10.25179/TJEM.2018-63449
M. Keskin, O. Tekin, A. Koca, M. Dağdeviren, G. Şimşek, M. Altay, D. Ertuğrul
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引用次数: 5
Top 100 Cited Articles in Thyroid Cancer: A Bibliometric Analysis 甲状腺癌前100篇被引文章:文献计量分析
Pub Date : 1900-01-01 DOI: 10.25179/tjem.2021-84035
V. B. Turhan, A. Ünsal
Objective: To identify and analyze the 100 most cited articles on thyroid cancer since 1975, thus, allowing their easy access for researchers in this field. Material and Methods: This study is a bibliometric analysis of research publications acquired from the Web of Science database. We evaluated the first 100 articles receiving the most citations in the field of thyroid cancer since 1975. Then, all research publications were compiled using journal information into different categories based on the study type, country, research centers, authors, and publication dates. All data were reported as percentages, numbers, and graphs. Results: In this study, we listed 8,608 full-length English-language articles. Our findings showed that the most cited article received 4,325 citations to date, while the Journal of Clinical Endocrinology Metabolism, a Thyroid journal, received the most number of citations (n:6531), publishing seventeen of the articles from our study. Also, thirty-two articles were from the field of oncology. The country with the most number of publications was the United States of America (n=70) in the years 2005, 2008, and 2009 (n=8). Conclusion: It is essential to acknowledge the top-cited articles in thyroid cancer since they contain essential information, research, and advances in its treatment. Our analysis of the first 100 articles included the most important papers with the most significant impact on thyroid cancer research. In our list, we acknowledged the most productive authors and institutions along with their research articles.
目的:对1975年以来被引次数最多的100篇关于甲状腺癌的文章进行识别和分析,为该领域的研究人员提供参考。材料和方法:本研究是对从Web of Science数据库获得的研究出版物进行文献计量学分析。我们评估了1975年以来在甲状腺癌领域中被引用最多的前100篇文章。然后,根据研究类型、国家、研究中心、作者和出版日期,利用期刊信息对所有研究出版物进行分类。所有数据均以百分比、数字和图表形式报告。结果:在本研究中,我们列出了8608篇完整的英文文章。我们的研究结果显示,迄今为止,被引用次数最多的文章被引用了4,325次,而被引用次数最多的是甲状腺杂志Journal of Clinical Endocrinology Metabolism (n:6531),发表了17篇来自我们研究的文章。此外,32篇文章来自肿瘤学领域。2005年、2008年和2009年发表论文最多的国家是美国(n=70) (n=8)。结论:了解被引用次数最多的甲状腺癌相关文章是必要的,因为它们包含了甲状腺癌治疗的基本信息、研究和进展。我们对前100篇文章的分析包括了对甲状腺癌研究影响最大的最重要的论文。在我们的榜单中,我们认可了最具生产力的作者和机构以及他们的研究文章。
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引用次数: 3
Determination of Serum Thyroid Hormones and Electrolytes in Hypothyroid and Hyperthyroid Females-A Case Control Study in Lahore, Pakistan 巴基斯坦拉合尔地区甲状腺功能低下和甲状腺功能亢进女性血清甲状腺激素和电解质的测定——病例对照研究
Pub Date : 1900-01-01 DOI: 10.25179/TJEM.2018-63502
Bushra Mubarak, S. Ashraf, Raheela Aslam
®Copyright 2019 by Turkish Journal of Endocrinology and Metabolism Association Turkish Journal of Endocrinology and Metabolism published by Türkiye Klinikleri Determination of Serum Thyroid Hormones and Electrolytes in Hypothyroid and Hyperthyroid Females-A Case Control Study in Lahore, Pakistan Hipotiroid ve Hipertiroid Kadınlarda Serum Tiroid Hormonları ve Elektrolitlerinin Belirlenmesi-Lahor, Pakistan'da Bir Vaka Kontrol Çalışması
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引用次数: 2
Growth Hormone Deficiency in the Transition Period 过渡时期生长激素缺乏
Pub Date : 1900-01-01 DOI: 10.25179/tjem.2019-65793
D. Vurallı
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引用次数: 0
Anti-Insulin Antibody Syndrome Following Alpha-Lipoic Acid Use in Turkish Patients: Report of Three New Cases 土耳其患者使用α -硫辛酸后的抗胰岛素抗体综合征:三例新病例报告
Pub Date : 1900-01-01 DOI: 10.25179/tjem.2021-83643
Emine Kartal Baykan
Anti-insulin antibody syndrome is a rare autoimmune disorder that is characterized by severe hypoglycemia, elevated blood insulin level, insulin autoantibodies, and the absence of pancreas islet cell pathology or exogenous insulin exposure. Alpha-lipoic acid is a sulfhydrylcontaining compound that is used to treat diabetic peripheral neuropathy and was first reported as a cause of anti-insulin antibody syndrome in Japan in 2003. In the literature, 17 cases with anti-insulin antibody syndrome following alpha-lipoic acid use have been reported from Japan, along with one case from Turkey, two from Korea, and seven cases from Italy. In this article, we present three cases with anti-insulin antibody syndrome developed after alpha-lipoic acid use. Case 1: A 72-year-old male patient was observed to have lost consciousness at home. This patient had no history of diabetes mellitus, diabetic medication, or insulin use. The patient complained of tiredness, palpitations, and sweating that began 3-4 h after eating but regressed after eating during the past month. The patient had a history of diagnosis with lumbar disk hernia two months ago and was using alpha-lipoic acid (600 mg). Case 2: A 67-year-old diabetic female patient using alpha-lipoic acid (600 mg) following the diagnosis of diabetic peripheral neuropathy. She complained of shivering and sweating two to three hours after a meal that started after starting alpha-lipoic acid therapy. Case 3: A 46-year-old male patient complained of fatigue, palpitations, and sweating for the last three weeks. Seven weeks ago, he started using alpha-lipoic acid (600 mg) after being diagnosed with carpal tunnel syndrome. The patients were diagnosed with anti-insulin antibody syndrome secondary to alpha-lipoic acid use, following which their alpha-lipoic therapy was discontinued. Alpha-lipoic acid is widely used in the treatment of diabetic peripheral neuropathy, nutritional support, or as an anti-aging agent. However, it should be noted that its use may cause anti-insulin antibody syndrome in genetically predisposed people.
抗胰岛素抗体综合征是一种罕见的自身免疫性疾病,其特征是严重低血糖,血胰岛素水平升高,胰岛素自身抗体,缺乏胰岛细胞病理或外源性胰岛素暴露。α -硫辛酸是一种含巯基的化合物,用于治疗糖尿病周围神经病变,2003年在日本首次报道为抗胰岛素抗体综合征的原因。在文献中,日本报告了17例使用α -硫辛酸后的抗胰岛素抗体综合征,土耳其1例,韩国2例,意大利7例。在本文中,我们报告了3例使用α -硫辛酸后出现的抗胰岛素抗体综合征。病例1:一名72岁男性患者在家中失去意识。患者无糖尿病史,无糖尿病药物史,无胰岛素使用史。患者主诉进食后3-4小时开始出现疲倦、心悸和出汗,但在过去一个月内进食后有所缓解。患者2个月前诊断为腰椎间盘突出,正在使用α -硫辛酸(600mg)。病例2:67岁糖尿病女性患者,诊断为糖尿病周围神经病变,应用α -硫辛酸(600 mg)治疗。她抱怨说,在开始α硫辛酸治疗后,饭后两到三个小时就开始发抖和出汗。病例3:46岁男性患者主诉疲劳、心悸、出汗近三周。七周前,在被诊断患有腕管综合征后,他开始服用α -硫辛酸(600毫克)。患者被诊断为继发于α -硫辛酸的抗胰岛素抗体综合征,随后停用α -硫辛酸治疗。α -硫辛酸广泛用于糖尿病周围神经病变的治疗、营养支持或作为抗衰老剂。然而,应该注意的是,它的使用可能会导致抗胰岛素抗体综合征的遗传易感性的人。
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引用次数: 1
Lipid Profile in the Elderly and Middle-Aged Patients with Type 2 Diabetes Mellitus in Relation with Gender 中老年2型糖尿病患者血脂与性别的关系
Pub Date : 1900-01-01 DOI: 10.25179/tjem.2019-66342
F. Saraç, S. Savaş, Bahattin Gökdemir, F. Akçiçek
D O I: 10 .2 51 79 /t je m .2 01 966 34 2 Objective: The aim of the present study was to determine the lipid profile in the elderly and middle-aged patients with Type 2 diabetes mellitus (DM) and its relation with gender. Material and Methods: A total of 592 patients with Type 2 DM aged ≥60 years and 269 diabetic patients aged <60 years as middle-aged with initial admissions or patients with two months of antihyperlipidemic medicine pause were recruited from the internal medicine outpatient clinic during December 2012-March 2018. Demographic and biochemical data were collected retrospectively. Abnormal lipid levels were accepted as total-cholesterol >200 mg/dL, low density lipoprotein-cholesterol (LDL-C) ≥100 mg/dL, triglyceride (TG) ≥150 mg/dL, and high density lipoproteincholesterol (HDL-C) <50 in women <40 mg/dL in men. Results: In total, 506 (85.4%) elderly and 248 (92.1%) middle-aged patients had one or more types of dyslipidemia. There were statistically significant differences in the frequencies of isolated high TG (x2=7.54, p=0.01) and combined two parameter dyslipidemia such as LDL-C ≥100 mg/dL & HDL-C <40 mg/dL & TG <150 mg/dL (x2=4.30, p=0.03) for men between elderly and middle-aged patients. Combined two-parameter dyslipidemia such as LDL-C ≥100 mg/dL, TG ≥150 mg/dL & HDL-C >50 mg/dL (x2=6.64, p=0.01), and isolated low HDL-C (x2=2.91, p=0.05) for women were found to be different between the elderly and middle-aged patients. Conclusion: Hypertriglyceridemia with high LDL-C and isolated low HDL-C were more common in the elderly women than that in middle-aged women where isolated hypertriglyceridemia and combined high LDL-C with low HDL-C were higher in the elderly than the middle-aged for men.
目的:探讨中老年2型糖尿病(DM)患者血脂水平及其与性别的关系。材料与方法:592例年龄≥60岁的2型糖尿病患者和269例年龄为200 mg/dL、低密度脂蛋白-胆固醇(LDL-C)≥100 mg/dL、甘油三酯(TG)≥150 mg/dL、高密度脂蛋白-胆固醇(HDL-C)≥50 mg/dL的糖尿病患者(x2=6.64, p=0.01)和女性分离性低HDL-C (x2=2.91, p=0.05)在中老年患者中存在差异。结论:高甘油三酯血症合并高LDL-C和孤立性低HDL-C在老年妇女中比在中年妇女中更常见,老年妇女中孤立性高甘油三酯血症和高LDL-C合并低HDL-C的发生率高于中年男性。
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引用次数: 1
Hospitalisation Cost of Diabetic Patients with Foot Ulcers: A Retrospective Descriptive Analysis from Turkey 糖尿病足溃疡患者的住院费用:来自土耳其的回顾性描述性分析
Pub Date : 1900-01-01 DOI: 10.25179/tjem.2021-82008
İ. H. Açar, N. Acar, Z. Sayiner, M. Araz, E. Akarsu
Objective: With the increase in the prevalence of diabetes and associated complications, most of the healthcare expenditure is due to treatments of diabetes complications. This study evaluated the determinants affecting the total treatment cost in hospitalized patients with diabetic foot ulcers (DFU), an important complication of diabetes. Material and Methods: Factors affecting cost in 300 cases of hospitalization due to DFU were analyzed retrospectively. Hospital invoices were examined, and incurred cost of each patient was calculated in Turkish lira and then converted into US dollars at the exchange rate on the date of hospitalization, considering the number of days of hospitalization. Results: Among the 300 included patients, the ratio of male/female participants was 1.94. The mean age of the patients was 62.6±11 years. Hemoglobin A1c mean was determined as 9.5±2.4%. The average hospitalization time was 17.8±12.9 days. When the average cost was analyzed according to Wagner phases, the average cost increased as the stage of the disease. The factor that most affected the cost was hospitalization cost (p=0.001, r=3.24). Diagnostic imaging tests affected the total cost the most (p=0.001, r=2.52) after hospitalization. Conclusion: The cost of hospitalization was the most important factor affecting the total cost in the analysis of DFU. Therefore, taking precautions before the advancement of ulcer stage and treatment at an early stage is expected to reduce the treatment cost. In addition, reducing the duration of hospital stay will be effective in reducing the cost of DFU treatment.
目的:随着糖尿病及其并发症患病率的增加,大部分医疗保健支出用于糖尿病并发症的治疗。本研究评估了影响糖尿病足溃疡(DFU)住院患者总治疗费用的决定因素,DFU是糖尿病的一个重要并发症。材料与方法:回顾性分析300例DFU住院费用影响因素。检查了医院发票,并以土耳其里拉计算每位患者的费用,然后考虑到住院天数,按住院当日的汇率换算成美元。结果:纳入的300例患者中,男女比例为1.94。患者平均年龄62.6±11岁。糖化血红蛋白平均值为9.5±2.4%。平均住院时间17.8±12.9 d。根据Wagner阶段分析平均成本时,平均成本随着疾病阶段的增加而增加。对成本影响最大的因素是住院费用(p=0.001, r=3.24)。诊断性影像学检查对住院后总费用影响最大(p=0.001, r=2.52)。结论:住院费用是影响DFU总费用的最重要因素。因此,在溃疡进展之前采取预防措施,在早期进行治疗,有望降低治疗成本。此外,缩短住院时间将有效降低DFU治疗的费用。
{"title":"Hospitalisation Cost of Diabetic Patients with Foot Ulcers: A Retrospective Descriptive Analysis from Turkey","authors":"İ. H. Açar, N. Acar, Z. Sayiner, M. Araz, E. Akarsu","doi":"10.25179/tjem.2021-82008","DOIUrl":"https://doi.org/10.25179/tjem.2021-82008","url":null,"abstract":"Objective: With the increase in the prevalence of diabetes and associated complications, most of the healthcare expenditure is due to treatments of diabetes complications. This study evaluated the determinants affecting the total treatment cost in hospitalized patients with diabetic foot ulcers (DFU), an important complication of diabetes. Material and Methods: Factors affecting cost in 300 cases of hospitalization due to DFU were analyzed retrospectively. Hospital invoices were examined, and incurred cost of each patient was calculated in Turkish lira and then converted into US dollars at the exchange rate on the date of hospitalization, considering the number of days of hospitalization. Results: Among the 300 included patients, the ratio of male/female participants was 1.94. The mean age of the patients was 62.6±11 years. Hemoglobin A1c mean was determined as 9.5±2.4%. The average hospitalization time was 17.8±12.9 days. When the average cost was analyzed according to Wagner phases, the average cost increased as the stage of the disease. The factor that most affected the cost was hospitalization cost (p=0.001, r=3.24). Diagnostic imaging tests affected the total cost the most (p=0.001, r=2.52) after hospitalization. Conclusion: The cost of hospitalization was the most important factor affecting the total cost in the analysis of DFU. Therefore, taking precautions before the advancement of ulcer stage and treatment at an early stage is expected to reduce the treatment cost. In addition, reducing the duration of hospital stay will be effective in reducing the cost of DFU treatment.","PeriodicalId":425605,"journal":{"name":"The Turkish Journal of Endocrinology and Metabolism","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128187048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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The Turkish Journal of Endocrinology and Metabolism
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