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A novel melanoma detection model: adapted K-means clustering-based segmentation process 一种新的黑色素瘤检测模型:基于k均值聚类的分割过程
IF 1.2 Q3 Computer Science Pub Date : 2020-11-12 DOI: 10.1515/bams-2020-0040
S. Sukanya, S. Jerine
Abstract Objectives The main intention of this paper is to propose a new Improved K-means clustering algorithm, by optimally tuning the centroids. Methods This paper introduces a new melanoma detection model that includes three major phase’s viz. segmentation, feature extraction and detection. For segmentation, this paper introduces a new Improved K-means clustering algorithm, where the initial centroids are optimally tuned by a new algorithm termed Lion Algorithm with New Mating Process (LANM), which is an improved version of standard LA. Moreover, the optimal selection is based on the consideration of multi-objective including intensity diverse centroid, spatial map, and frequency of occurrence, respectively. The subsequent phase is feature extraction, where the proposed Local Vector Pattern (LVP) and Grey-Level Co-Occurrence Matrix (GLCM)-based features are extracted. Further, these extracted features are fed as input to Deep Convolution Neural Network (DCNN) for melanoma detection. Results Finally, the performance of the proposed model is evaluated over other conventional models by determining both the positive as well as negative measures. From the analysis, it is observed that for the normal skin image, the accuracy of the presented work is 0.86379, which is 47.83% and 0.245% better than the traditional works like Conventional K-means and PA-MSA, respectively. Conclusions From the overall analysis it can be observed that the proposed model is more robust in melanoma prediction, when compared over the state-of-art models.
摘要目的本文的主要目的是通过优化质心,提出一种新的改进的K-means聚类算法。方法介绍一种新的黑色素瘤检测模型,该模型包括分割、特征提取和检测三个主要阶段。对于分割,本文介绍了一种新的改进的K-means聚类算法,其中初始质心由一种新算法——新匹配过程的Lion算法(LANM)进行优化调整,该算法是标准LA的改进版本,和发生频率。随后的阶段是特征提取,其中提取所提出的基于局部向量模式(LVP)和灰度共生矩阵(GLCM)的特征。此外,将这些提取的特征作为输入提供给用于黑色素瘤检测的深度卷积神经网络(DCNN)。结果最后,通过确定正测度和负测度来评估所提出的模型相对于其他传统模型的性能。从分析中可以看出,对于正常皮肤图像,所提出的工作的准确度为0.86379,分别比传统的K-means和PA-MSA等工作提高了47.83%和0.245%。结论从总体分析可以看出,与现有技术的模型相比,所提出的模型在黑色素瘤预测方面更稳健。
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引用次数: 4
Jaya Spider Monkey Optimization-driven Deep Convolutional LSTM for the prediction of COVID’19 基于Jaya Spider Monkey优化驱动的深度卷积LSTM预测COVID ' 19
IF 1.2 Q3 Computer Science Pub Date : 2020-11-12 DOI: 10.1515/bams-2020-0030
S. Chander, Vijaya Padmanabha, Joseph Mani
Abstract COVID’19 is an emerging disease and the precise epidemiological profile does not exist in the world. Hence, the COVID’19 outbreak is treated as a Public Health Emergency of the International Concern by the World Health Organization (WHO). Hence, an effective and optimal prediction of COVID’19 mechanism, named Jaya Spider Monkey Optimization-based Deep Convolutional long short-term classifier (JayaSMO-based Deep ConvLSTM) is proposed in this research to predict the rate of confirmed, death, and recovered cases from the time series data. The proposed COVID’19 prediction method uses the COVID’19 data, which is the trending domain of research at the current era of fighting the COVID’19 attacks thereby, to reduce the death toll. However, the proposed JayaSMO algorithm is designed by integrating the Spider Monkey Optimization (SMO) with the Jaya algorithm, respectively. The Deep ConvLSTM classifier facilitates to predict the COVID’19 from the time series data based on the fitness function. Besides, the technical indicators, such as Relative Strength Index (RSI), Rate of Change (ROCR), Exponential Moving Average (EMA), Williams %R, Double Exponential Moving Average (DEMA), and Stochastic %K, are extracted effectively for further processing. Thus, the resulted output of the proposed JayaSMO-based Deep ConvLSTM is employed for COVID’19 prediction. Moreover, the developed model obtained the better performance using the metrics, like Mean Square Error (MSE), and Root Mean Square Error (RMSE) by considering confirmed, death, and the recovered cases of COVID’19 for China and Oman. Thus, the proposed JayaSMO-based Deep ConvLSTM showed improved results with a minimal MSE of 1.791, and the minimal RMSE of 1.338 based on confirmed cases in Oman. In addition, the developed model achieved the death cases with the values of 1.609, and 1.268 for MSE and RMSE, whereas the MSE and the RMSE value of 1.945, and 1.394 is achieved by the developed model using recovered cases in China.
COVID - 19是一种新兴疾病,全球尚不存在精确的流行病学概况。因此,新冠肺炎疫情被世界卫生组织(WHO)定为“国际关注的突发公共卫生事件”。因此,本研究提出了一种有效且最优的COVID - 19预测机制,即基于Jaya蜘蛛猴优化的深度卷积长短期分类器(JayaSMO-based Deep ConvLSTM),从时间序列数据中预测确诊率、死亡率和康复率。新冠肺炎预测方法利用了当前抗击新冠肺炎攻击的研究趋势领域COVID - 19数据,从而减少了死亡人数。本文提出的JayaSMO算法是将蜘蛛猴优化(SMO)算法与Jaya算法相结合而设计的。Deep ConvLSTM分类器便于基于适应度函数从时间序列数据中预测COVID ' 19。此外,对相对强弱指数(RSI)、变化率(ROCR)、指数移动平均线(EMA)、Williams %R、双指数移动平均线(DEMA)、随机%K等技术指标进行了有效提取,以供进一步处理。因此,所提出的基于jayasmo的深度ConvLSTM的结果输出用于COVID ' 19预测。此外,考虑中国和阿曼的确诊病例、死亡病例和康复病例,采用均方误差(MSE)和均方根误差(RMSE)等指标,所建立的模型获得了更好的性能。因此,基于jayasmo的Deep ConvLSTM的最小均方根误差为1.791,基于阿曼确诊病例的最小均方根误差为1.338。此外,所建立的模型对死亡病例的MSE和RMSE分别为1.609和1.268,而对中国恢复病例的MSE和RMSE分别为1.945和1.394。
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引用次数: 9
Analysis of brain waves changes in stressful situations based on horror game with the implementation of virtual reality and brain-computer interface system: a case study 基于虚拟现实和脑机接口系统的恐怖游戏压力情境下脑电波变化分析
IF 1.2 Q3 Computer Science Pub Date : 2020-11-04 DOI: 10.1515/bams-2020-0050
Natalia Browarska, Aleksandra Kawala-Sterniuk, Przemysław Chechelski, J. Zygarlicki
Abstract Objectives This presents a case for fear and stress stimuli and afterward EEG data analysis. Methods The stress factor had been evoked by a computer horror game correlated with virtual reality (VR) and brain-computer interface (BCI) from OpenBCI, applied for the purpose of brain waves changes observation. Results Results obtained during the initial study were promising and provide conclusions for further research in this field carried out on an expanded group of involved participants. Conclusions The study provided very promising and interesting results. Further investigation with larger amount of participants will be carried out.
摘要目的介绍一个恐惧和应激刺激的病例,并分析之后的脑电图数据。方法利用OpenBCI中与虚拟现实(VR)和脑机接口(BCI)相关的电脑恐怖游戏诱发应激因子,观察脑电波变化。在初步研究中获得的结果是有希望的,并为该领域在扩大的参与者群体中进行的进一步研究提供了结论。结论本研究提供了非常有希望和有趣的结果。将进行更多参与者的进一步调查。
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引用次数: 3
An empirical survey of electroencephalography-based brain-computer interfaces 基于脑电图的脑机接口的实证研究
IF 1.2 Q3 Computer Science Pub Date : 2020-11-03 DOI: 10.1515/bams-2019-0053
M. Wankhade, S. Chorage
Abstract Objectives The Electroencephalogram (EEG) signal is modified using the Motor Imagery (MI) and it is utilized for patients with high motor impairments. Hence, the direct relationship between the computer and brain is termed as an EEG-based brain-computer interface (BCI). The objective of this survey is to presents an analysis of the existing distinct BCIs based on EEG. Methods This survey provides a detailed review of more than 60 research papers presenting the BCI-based EEG, like motor imagery-based techniques, spatial filtering-based techniques, Steady-State Visual Evoked Potential (SSVEP)-based techniques, machine learning-based techniques, Event-Related Potential (ERP)-based techniques, and online EEG-based techniques. Subsequently, the research gaps and issues of several EEG-based BCI systems are adopted to help the researchers for better future scope. Results An elaborative analyses as well as discussion have been provided by concerning the parameters, like evaluation metrics, year of publication, accuracy, implementation tool, and utilized datasets obtained by various techniques. Conclusions This survey paper exposes research topics on BCI-based EEG, which helps the researchers and scholars, who are interested in this domain.
摘要目的利用运动图像(MI)对脑电图(EEG)信号进行修改,并将其用于高运动损伤患者。因此,计算机和大脑之间的直接关系被称为基于脑电的脑机接口(BCI)。本调查的目的是对现有的基于脑电图的不同脑机接口进行分析。方法本次调查对60多篇基于脑机接口的脑电研究论文进行了详细回顾,包括基于运动图像的技术、基于空间滤波的技术、稳态视觉诱发电位(SSVEP)的技术、机器学习的技术、事件相关电位(ERP)的技术和在线脑电技术。随后,采用了几种基于脑电的脑机接口系统的研究空白和问题,以帮助研究人员获得更好的未来范围。结果对评价指标、发表年份、准确性、实施工具和通过各种技术获得的使用数据集等参数进行了详细的分析和讨论。结论本文揭示了基于脑机接口的脑电研究课题,有助于对该领域感兴趣的研究人员和学者。
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引用次数: 1
Initial study on changes in activity of brain waves during audio stimulation using noninvasive brain–computer interfaces: choosing the appropriate filtering method 使用无创脑机接口对音频刺激过程中脑电波活动变化的初步研究:选择合适的滤波方法
IF 1.2 Q3 Computer Science Pub Date : 2020-10-29 DOI: 10.1515/bams-2020-0051
Natalia Browarska, Aleksandra Kawala-Sterniuk, J. Zygarlicki
Abstract Objectives In this paper series of experiments were carried out in order to check the influence of various sounds on human concentration during visually stimulated tasks performance. Methods The obtained data was filtered. For the study purposes various smoothing filters were tested, including Median and Savitzky–Golay Filters; however, median filter only was applied. Implementation of this filter made the obtained data more legible and useful for potential diagnostics purposes. The tests were carried out with the implementation of the Emotiv Flex EEG headset. Results The obtained results were promising and complied with the initial assumptions, which stated that the “relax”-phase, despite relaxing sounds stimuli, is strongly affected with the “focus”-phase with distracting sounds, which is clearly visible in the shape of the recorded EEG data. Conclusions Further investigations with broader range of subjects is being currently carried out in order to confirm the already obtained results.
摘要目的通过一系列实验,考察不同声音对人在视觉刺激任务中注意力的影响。方法对所得数据进行筛选。为了研究目的,我们测试了各种平滑滤波器,包括中值滤波器和Savitzky-Golay滤波器;然而,只应用中值滤波。该过滤器的实现使获得的数据更清晰,对潜在的诊断目的更有用。这些测试是通过Emotiv Flex脑电图头戴设备进行的。结果所得到的结果符合最初的假设,即尽管有放松的声音刺激,但“放松”阶段仍受到有分散声音的“集中”阶段的强烈影响,这在记录的脑电图数据中清晰可见。结论:目前正在开展范围更广的进一步调查,以确认已经获得的结果。
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引用次数: 4
Deep learning of the role of interleukin IL-17 and its action in promoting cancer 深入学习白细胞介素IL-17的作用及其在促癌中的作用
IF 1.2 Q3 Computer Science Pub Date : 2020-10-17 DOI: 10.1515/bams-2020-0052
Alessandro Nutini, A. Sohail
Abstract In breast cancer patients, metastasis remains a major cause of death. The metastasis formation process is given by an interaction between the cancer cells and the microenvironment that surrounds them. In this article, we develop a mathematical model that analyzes the role of interleukin IL-17 and its action in promoting cancer and in facilitating tissue metastasis in breast cancer, using a dynamic analysis based on a stochastic process that accounts for the local and global action of this molecule. The model uses the Ornstein–Uhlembeck and Markov process in continuous time. It focuses on the oncological expansion and the interaction between the interleukin IL-17 and cell populations This analysis tends to clarify the processes underlying the metastasis expansion mechanism both for a better understanding of the pathological event and for a possible better control of therapeutic strategies. IL-17 is a proinflammatory interleukin that acts when there is tissue damage or when there is a pathological situation caused by an external pathogen or by a pathological condition such as cancer. This research is focused on the role of interleukin IL-17 which, especially in the case of breast cancer, turns out to be a dominant “communication pin” since it interconnects with the activity of different cell populations affected by the oncological phenomenon. Stochastic modeling strategies, specially the Ornstein-Uhlenbeck process, with the aid of numerical algorithms are elaborated in this review. The role of IL-17 is discussed in this manuscript at all the stages of cancer. It is discussed that IL-17 also acts as “metastasis promoter” as a result of its proinflammatory nature. The stochastic nature of IL-17 is discussed based on the evidence provided by recent literature. The resulting dynamical analysis can help to select the most appropriate therapeutic strategy. Cancer cells, in the case of breast cancer, have high level of IL-17 receptors (IL-17R); therefore the interleukin itself has direct effects on these cells. Immunotherapy research, focused on this cytokine and interlinked with the stochastic modeling, seems to be a promising avenue.
在乳腺癌患者中,转移仍然是死亡的主要原因。转移的形成过程是由癌细胞和周围微环境的相互作用决定的。在本文中,我们建立了一个数学模型来分析白细胞介素IL-17的作用及其在乳腺癌中促进癌症和促进组织转移的作用,使用基于随机过程的动态分析来解释该分子的局部和全局作用。该模型采用连续时间的Ornstein-Uhlembeck和Markov过程。它侧重于肿瘤扩展和白细胞介素IL-17与细胞群之间的相互作用,这种分析倾向于阐明转移扩展机制的过程,以便更好地理解病理事件,并可能更好地控制治疗策略。IL-17是一种促炎白介素,在组织损伤或由外部病原体或癌症等病理状况引起的病理情况下起作用。这项研究的重点是白细胞介素IL-17的作用,特别是在乳腺癌的情况下,它被证明是一个主要的“通讯针”,因为它与受肿瘤现象影响的不同细胞群的活动相互联系。本文阐述了基于数值算法的随机建模策略,特别是Ornstein-Uhlenbeck过程。本文讨论了IL-17在癌症各个阶段的作用。本文还讨论了IL-17由于其促炎性质也可作为“转移促进子”。根据近年来的文献资料,讨论了IL-17的随机性。结果的动力学分析可以帮助选择最合适的治疗策略。以乳腺癌为例,癌细胞具有高水平的IL-17受体(IL-17R);因此,白细胞介素本身对这些细胞有直接作用。以该细胞因子为研究重点,结合随机建模的免疫治疗研究,似乎是一条很有前景的研究途径。
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引用次数: 4
Robust controller for cancer chemotherapy dosage using nonlinear kernel-based error function 基于非线性误差函数的癌症化疗剂量鲁棒控制器
IF 1.2 Q3 Computer Science Pub Date : 2020-09-28 DOI: 10.1515/BAMS-2019-0056
U. L. Mohite, H. Patel
Abstract It is well-known that chemotherapy is the most significant method on curing the most death-causing disease like cancer. These days, the use of controller-based approach for finding the optimal rate of drug injection throughout the treatment has increased a lot. Under these circumstances, this paper establishes a novel robust controller that influences the drug dosage along with parameter estimation. A new nonlinear error function-based extended Kalman filter (EKF) with improved scaling factor (NEF-EKF-ISF) is introduced in this research work. In fact, in the traditional schemes, the error is computed using the conventional difference function and it is deployed for the updating process of EKF. In our previous work, it has been converted to the nonlinear error function. Here, the updating process is based on the prior error function, though scaled to a nonlinear environment. In addition, a scaling factor is introduced here, which considers the historical error improvement, for the updating process. Finally, the performance of the proposed controller is evaluated over other traditional approaches, which implies the appropriate impact of drug dosage injection on normal, immune and tumor cells. Moreover, it is observed that the proposed NEF-EKF-ISF has the ability to evaluate the tumor cells with a better accuracy rate.
摘要众所周知,化疗是治疗癌症等致死率最高的疾病的最重要的方法。如今,在整个治疗过程中,使用基于控制器的方法来寻找药物注射的最佳速率已经增加了很多。在这种情况下,本文建立了一种新的鲁棒控制器,该控制器随参数估计影响药物剂量。本文提出了一种新的基于非线性误差函数的改进比例因子扩展卡尔曼滤波器(NEF-EKF-ISF)。实际上,在传统的方案中,误差是使用传统的差分函数计算的,并将其用于EKF的更新过程。在我们之前的工作中,它已被转换为非线性误差函数。在这里,更新过程是基于先验误差函数的,尽管缩放到非线性环境。此外,本文还引入了一个考虑历史误差改进的比例因子,用于更新过程。最后,与其他传统方法相比,对所提出的控制器的性能进行了评估,这意味着药物剂量注射对正常细胞,免疫细胞和肿瘤细胞的适当影响。此外,观察到所提出的NEF-EKF-ISF能够以更好的准确率评估肿瘤细胞。
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引用次数: 2
Cooperation of CUDA and Intel multi-core architecture in the independent component analysis algorithm for EEG data 基于CUDA和Intel多核架构的脑电数据独立分量分析算法
IF 1.2 Q3 Computer Science Pub Date : 2020-09-01 DOI: 10.1515/BAMS-2020-0044
Anna Gajos-Balinska, Grzegorz M. Wójcik, Przemysław Stpiczyński
Abstract Objectives The electroencephalographic signal is largely exposed to external disturbances. Therefore, an important element of its processing is its thorough cleaning. Methods One of the common methods of signal improvement is the independent component analysis (ICA). However, it is a computationally expensive algorithm, hence methods are needed to decrease its execution time. One of the ICA algorithms (fastICA) and parallel computing on the CPU and GPU was used to reduce the algorithm execution time. Results This paper presents the results of study on the implementation of fastICA, which uses some multi-core architecture and the GPU computation capabilities. Conclusions The use of such a hybrid approach shortens the execution time of the algorithm.
目的脑电图信号在很大程度上暴露于外界干扰。因此,其加工的一个重要因素是它的彻底清洗。方法独立分量分析(ICA)是常用的信号改进方法之一。然而,它是一个计算量很大的算法,因此需要方法来减少它的执行时间。为了缩短算法的执行时间,采用了一种ICA算法(fastICA),并在CPU和GPU上进行并行计算。结果本文给出了利用一些多核架构和GPU计算能力实现fastICA的研究结果。结论采用这种混合方法可以缩短算法的执行时间。
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引用次数: 0
Overview of the holographic-guided cardiovascular interventions and training – a perspective 全息引导心血管干预和训练综述-一个视角
IF 1.2 Q3 Computer Science Pub Date : 2020-09-01 DOI: 10.1515/BAMS-2020-0043
Klaudia Proniewska, A. Pręgowska, P. Walecki, Damian Dolega-Dolegowski, R. Ferrari, D. Dudek
Abstract Immersive technologies, like Virtual Reality (VR), Augmented Reality (AR) and Mixed Reality (MR) have undergone technical evolutions over the last few decades. Their rapid development and dynamic changes enable their effective applications in medicine, in fields like imaging, preprocedural planning, treatment, operations planning, medical students training, and active support during therapeutic and rehabilitation procedures. Within this paper, a comprehensive analysis of VR/AR/MR application in the medical industry and education is presented. We overview and discuss our previous experience with AR/MR and 3D visual environment and MR-based imaging systems in cardiology and interventional cardiology. Our research shows that using immersive technologies users can not only visualize the heart and its structure but also obtain quantitative feedback on their location. The MR-based imaging system proposed offers better visualization to interventionists and potentially helps users understand complex operational cases. The results obtained suggest that technology using VR/AR/MR can be successfully used in the teaching process of future doctors, both in aspects related to anatomy and clinical classes. Moreover, the system proposed provides a unique opportunity to break the boundaries, interact in the learning process, and exchange experiences inside the medical community.
沉浸式技术,如虚拟现实(VR)、增强现实(AR)和混合现实(MR),在过去的几十年里经历了技术的演变。它们的快速发展和动态变化使其在医学、成像、术前计划、治疗、手术计划、医学生培训以及治疗和康复过程中的积极支持等领域得到有效应用。本文全面分析了VR/AR/MR在医疗行业和教育领域的应用。我们概述并讨论了我们以前在心脏病学和介入性心脏病学中的AR/MR和3D视觉环境以及基于MR的成像系统方面的经验。我们的研究表明,使用沉浸式技术,用户不仅可以可视化心脏及其结构,还可以获得有关其位置的定量反馈。提出的基于核磁共振的成像系统为介入医生提供了更好的可视化,并有可能帮助用户理解复杂的手术病例。结果表明,VR/AR/MR技术可以成功地应用于未来医生的教学过程中,无论是在解剖学方面还是在临床课程方面。此外,提出的系统提供了一个独特的机会,打破边界,在学习过程中互动,并在医学界内交流经验。
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引用次数: 1
Recognition of multifont English electronic prescribing based on convolution neural network algorithm 基于卷积神经网络算法的多字体英文电子处方识别
IF 1.2 Q3 Computer Science Pub Date : 2020-09-01 DOI: 10.1515/BAMS-2020-0021
M. Mohammed, E. Mohammed, Mohammed S. Jarjees
Abstract The printed character recognition is an efficient and automatic method for inputting information to a computer nowadays that is used to translate the printed or handwritten images into an editable and readable text file. This paper aims to recognize a multifont and multisize of the English language printed word for a smart pharmacy purpose. The recognition system has been based on a convolution neural network (CNN) approach where line, word, and character are separately corrected, and then each of the separated characters is fed into the CNN algorithm for recognition purposes. The OpenCV open-source library has been used for preprocessing, which can segment English characters accurately and efficiently, and for recognition, the Keras library with the backend of TensorFlow has been used. The training and testing data sets have been designed to include 23 different fonts with six different sizes. The CNN algorithm achieves the highest accuracy of 96.6% comparing to the other state-of-the-art machine learning methods. The higher classification accuracy of the CNN approach shows that this type of algorithm is ideal for the English language printed word recognition. The highest error rate after testing the system using English electronic prescribing written with all proposed font-types is 0.23% in Georgia font.
摘要印刷字符识别是一种高效、自动的计算机信息输入方法,用于将印刷或手写图像转换为可编辑、可读的文本文件。本文旨在识别多字体、多尺寸的英语印刷词,以实现智能药房的目的。识别系统基于卷积神经网络(CNN)方法,其中行、单词和字符被分别校正,然后每个分离的字符被输入到CNN算法中用于识别目的。OpenCV开源库已用于预处理,可以准确高效地分割英文字符;识别方面,使用了带有TensorFlow后端的Keras库。训练和测试数据集被设计为包括23种不同字体和6种不同大小。与其他最先进的机器学习方法相比,CNN算法实现了96.6%的最高精度。CNN方法具有较高的分类精度,表明该算法是英语印刷字识别的理想算法。在使用所有拟议字体类型编写的英语电子处方测试系统后,乔治亚字体的最高错误率为0.23%。
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引用次数: 8
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Bio-Algorithms and Med-Systems
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