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2020 Medical Technologies Congress (TIPTEKNO)最新文献

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Light-Induced Bactericidal Effect of Wound Dressings Produced from Thermoplastic Polyurethane and Chitosan 热塑性聚氨酯-壳聚糖创面敷料的光致杀菌效果
Pub Date : 2020-11-19 DOI: 10.1109/TIPTEKNO50054.2020.9299288
Sevilay Çetin, Merve Başaranbilek, Hilal Er, Emel Bakay, M. Seydibeyoğlu, N. Topaloglu
Tissue damage or disruption of tissue continuity is called as wound. Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial strain that can cause infection on the wounds, and especially control of the infections plays an important role in the wound healing process. Wound dressings are an alternative method that can be used to shorten wound healing time. At the same time, bacterial infection is tried to be prevented in the wound area by adding antibacterial materials to the contents of the dressing materials. Light applications of certain wavelengths are another method that shows antibacterial effect used in wound infection treatment. In this study, wound dressings were produced by electrospinning method using chitosan (CHT) and thermoplastic polyurethane (TPU) materials. Also, the synergistic antibacterial effects of wound dressings and 808 nm laser light were investigated on Methicillin-resistant Staphylococcus aureus (MRSA). It was observed that the wound dressings produced with TPU and CHT have antibacterial properties and the laser light at 808 nm of wavelength increases the antibacterial efficacy of the dressings. TPU and TPU-CHT wound dressings have a synergistic antibacterial effect when induced with 808 nm laser light. Thus, light induced nanofibers can be an efficient tool to improve the treatments of infected wounds.
组织损伤或组织连续性中断称为伤口。耐甲氧西林金黄色葡萄球菌(MRSA)是一种可引起伤口感染的细菌菌株,特别是感染的控制在伤口愈合过程中起着重要作用。创面敷料是缩短创面愈合时间的另一种方法。同时,在敷料内容物中加入抗菌材料,尽量防止创面细菌感染。特定波长的光应用是伤口感染治疗中显示抗菌效果的另一种方法。本研究以壳聚糖(CHT)和热塑性聚氨酯(TPU)为原料,采用静电纺丝法制备伤口敷料。同时,研究创面敷料与808 nm激光对耐甲氧西林金黄色葡萄球菌(MRSA)的协同抑菌作用。观察到TPU和CHT制备的伤口敷料具有抗菌性能,808 nm波长的激光可提高敷料的抗菌效果。在808 nm激光诱导下,TPU和TPU- cht伤口敷料具有协同抗菌作用。因此,光诱导纳米纤维可以成为改善感染伤口治疗的有效工具。
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引用次数: 1
Classification of Brain Tumors via Deep Learning Models 基于深度学习模型的脑肿瘤分类
Pub Date : 2020-11-19 DOI: 10.1109/TIPTEKNO50054.2020.9299231
Kaya Dağlı, O. Eroğul
Brain tumors threathen human health significantly. Misdiagnosis of these tumors decrease effectiveness of decisions for intervention and patient’s state of health. The conventional method to differentiate brain tumors is by the inspection of magnetic resonance images by clinicians. Since there are various types of brain tumors and there are many images that clinicians should examine, this method is both prone to human errors and causes excessive time consumption. In this study, the most common brain tumor types; Glioma, Meningioma and Pituitary are classified using deep learning models. While the main objective of this study is to have a high rate of accuracy, the time spent is also examined. The aim of this study is to ease clinicians work load and have a time efficient classification system. The system which has been built has an accuracy up to 90%.
脑肿瘤严重威胁人类健康。这些肿瘤的误诊会降低干预决策的有效性和患者的健康状况。常规的方法来区分脑肿瘤是由临床医生检查磁共振图像。由于脑肿瘤的类型多种多样,临床医生需要检查的图像也很多,这种方法容易出现人为错误,也会造成过多的时间消耗。在这项研究中,最常见的脑肿瘤类型;神经胶质瘤、脑膜瘤和垂体瘤使用深度学习模型进行分类。虽然本研究的主要目的是要有一个高的准确率,时间花费也检查。本研究的目的是减轻临床医生的工作量,并有一个时间效率的分类系统。该系统的检测精度可达90%。
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引用次数: 2
Determination of Cell Stiffness Using Polymer Microbeads as Reference 以聚合物微珠为基准测定细胞刚度
Pub Date : 2020-11-19 DOI: 10.1109/TIPTEKNO50054.2020.9299227
Sevde Omeroglu, Rahmetullah Varol, Z. Karavelioglu, Aslıhan Karadağ, Y. Başbınar, Muhammed Enes ORUC, H. Uvet
Knowing the mechanical properties of cells is very important in cell detection, analysis of cell activities, diagnosis and drug treatment. The determination of cell stiffness, which used effectively in cell analysis, is carried out with different measurement techniques. In this study, the stiffness of cells is determined by comparison to the displacement of polystyrene microparticles induced by vibration generated by piezoelectric transducers. The difference of stiffness of the cells and polystyrene microparticles is measured using a digital holographic imaging technique.
了解细胞的力学性质在细胞检测、细胞活性分析、诊断和药物治疗中具有重要意义。在细胞分析中有效使用的细胞刚度的测定采用不同的测量技术进行。在这项研究中,通过比较由压电换能器产生的振动引起的聚苯乙烯微粒的位移来确定细胞的刚度。采用数字全息成像技术测量了聚苯乙烯微粒子与细胞的刚度差。
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引用次数: 0
Classification and Statistical Analysis of Schizophrenic and Normal EEG Time Series 精神分裂症与正常人脑电图时间序列的分类与统计分析
Pub Date : 2020-11-19 DOI: 10.1109/TIPTEKNO50054.2020.9299246
Delal Şeker, M. S. Özerdem
In this study, discrimination of normal and schizophrenic EEG is aimed by using lineer features with different classifiers. Fort his purpose, 1 minutes of EEG records through 16 channels were recorded from 39 normal and 39 schizophrenia patients and minimum, maximum, mean, standard deviation and median feautes were extracted from these records. k-neighbors, Multi-layer perceptron, support vector machines and Random forest classifier were applied to feature vectors extracted from each channel. Highest classification accuracy is reached to 99.95% in proposed work. While MLP seems to be best classifier, channel C4 is observed most relevant to discriminate schizophrenic EEG from healthy control group. As a result of independent sample t-test and Mann-Whitney U Test for the purpose of statistical analysis, there is a distinct statistical significance for whole channels.When considering proposed work, obtained results are so promising and make contributions to literatüre view according to related works.
在本研究中,利用不同分类器的线性特征对正常脑电图和精神分裂症脑电图进行区分。为此,我们分别记录了39例正常人和39例精神分裂症患者16个通道的1分钟脑电图记录,并从中提取最小、最大、平均值、标准差和中位数特征。将k-邻域、多层感知器、支持向量机和随机森林分类器应用于每个通道提取的特征向量。该方法的分类准确率最高可达99.95%。虽然MLP似乎是最好的分类器,但C4通道与区分精神分裂症脑电图与健康对照组最相关。通过独立样本t检验和Mann-Whitney U检验进行统计分析,整个渠道的统计显著性显著。在考虑拟开展的工作时,所获得的结果非常有希望,并根据相关工作对文献综述做出贡献。
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引用次数: 0
Interferometric Investigation of Cell Stiffness and Morphology on Oxidative Stress- Induced Human Umbilical Vein Endothelial Cells (HUVEC) 氧化应激诱导的人脐静脉内皮细胞(HUVEC)细胞刚度和形态学的干涉研究
Pub Date : 2020-11-19 DOI: 10.1109/TIPTEKNO50054.2020.9299252
Z. Karavelioglu, Rahmetullah Varol, Sevde Omeroglu, Hanife E. Meco, Yagmur Buyrukbilen, Y. Başbınar, M. E. Oruc, H. Uvet
Cell stiffness that can be measured accordingly elasticity modulus is an important biomechanical feature that plays a one-to-one role on the basic features of the cell, such as migration and proliferation, and this feature is significantly affected by the characteristic of the cytoskeleton. Reactive Oxygen Species (ROS) are side-products formed as a result of the cell’s general metabolic activities. Cells have a very effective antioxidant defense to deactivate the toxic effect of ROS however, oxidative stress at abnormal levels significantly damages cellular balance. Many conditions such as inflammation, neurodegenerative and cardiovascular diseases and aging are associated with oxidative stress. Besides, oxidative stress is one of the parameters that affect the biomechanical behavior of the cell, but the mechanism of this effect still remains a mystery. In this study, oxidative stress was mimicked on Human Umbilical Vein Endothelial (HUVEC) cells by using H2 O2 and the effect of this situation on cell stiffness and morphological structure was investigated interferometrically for the first time. The changes that occurred in the cell stiffness were determined by calculating the elasticity modules of the cells. Cells were exposed to H2 O2 for 24 hours at 0.5 mM and 1 mM concentrations, and as a result, cell stiffness was shown to decrease due to increased H2 O2 concentration.
弹性模量是一种重要的生物力学特征,它对细胞的迁移、增殖等基本特征起着一对一的作用,而这一特征受到细胞骨架特性的显著影响。活性氧(ROS)是由于细胞一般代谢活动而形成的副产物。细胞有一种非常有效的抗氧化防御来消除ROS的毒性作用,然而,异常水平的氧化应激会显著破坏细胞平衡。许多疾病,如炎症、神经退行性疾病、心血管疾病和衰老都与氧化应激有关。此外,氧化应激是影响细胞生物力学行为的参数之一,但其作用机制仍是一个谜。本研究采用H2 O2模拟氧化应激对人脐静脉内皮细胞(HUVEC)的影响,并首次采用干涉测量法研究了氧化应激对细胞刚度和形态结构的影响。细胞刚度的变化是通过计算细胞的弹性模块来确定的。细胞在0.5 mM和1 mM浓度的H2 O2中暴露24小时,结果显示,细胞硬度由于H2 O2浓度的增加而降低。
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引用次数: 0
Investigation on the Use of Hidden Layers, Different Numbers of Neurons and Different Activation Functions to Detect Pupil Dilation Responses to Stress 利用隐藏层、不同神经元数和不同激活函数检测瞳孔对压力的扩张反应的研究
Pub Date : 2020-11-19 DOI: 10.1109/TIPTEKNO50054.2020.9299221
Abdullah Nuri Somuncuoğlu, V. Purutçuoğlu, F. Arı, D. Gökçay
Stress is an important problem for people that causes health problems and economic losses. When it becomes chronic, it paves the way for many diseases. Studies in this area have made significant progress in measuring stress levels with the help of data from wearable devices and sensors. In this study, using supervised deep learning methods, we worked on the detection of pupil dilation, which is accepted as one of the stress indicators. In our experiment, two different films containing positive and funny scenes and negative and stressful scenes were shown to the participants. Meanwhile, the pupil diameter was measured continuously. After the obtained signals were cleared of noises, deep learning studies were carried out on them. With these experiments, the effect of different activation functions used in hidden layers along with the different number of hidden layers and neuron numbers on learning were examined. After the trials with Hyperbolic Tangent, ReLU and Swish activation functions, the highest accuracy for classifying the stress of the participants from their pupil responses was obtained with the Swish activation function with 90.79%.
压力对人们来说是一个重要的问题,它会导致健康问题和经济损失。当它变成慢性时,它就为许多疾病铺平了道路。在可穿戴设备和传感器数据的帮助下,该领域的研究在测量应力水平方面取得了重大进展。在本研究中,我们使用监督深度学习方法对瞳孔扩张进行检测,瞳孔扩张被认为是压力指标之一。在我们的实验中,我们向参与者播放了两部不同的电影,其中包括积极有趣的场景和消极紧张的场景。同时连续测量瞳孔直径。将得到的信号去噪后,对其进行深度学习研究。通过这些实验,考察了隐藏层中不同激活函数以及不同隐藏层数和神经元数对学习的影响。使用双曲正切、ReLU和Swish激活函数进行实验后,Swish激活函数对被试瞳孔反应的压力分类准确率最高,为90.79%。
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引用次数: 0
IoT-Based Motion Tracking System for Orthopedic Patients and Athletes 基于物联网的骨科患者和运动员运动跟踪系统
Pub Date : 2020-11-19 DOI: 10.1109/TIPTEKNO50054.2020.9299223
Gizem Çoban, Faruk Aktas
Smart exercises are reliable and motivating activities that reduce the possibility of injury, and improve the muscle-bone system. When it is made unconscious movements, it can cause either harm to her/his body or slow down the development of exercise. In this study, it is aimed to study both orthopedic patients and athletes. Thanks to the developed algorithm and equipment, the main theme is doing the exercise correctly in given plan within the personal limits. Depending on the purpose of use, according to the program planned by the doctor or trainer, the system gives a notification when a person (after wears the elbow / knee brace) performs the desired movement with the desired degree. The person understands that the movement has been made successfully from this alert. The processes that continue until reaching the result of the exercise can be stored simultaneously on the ThingSpeak Cloud Platform and can be monitored on the linear graph with the via wireless network. With the developed mobile application, the person can instantly see the angle of movement and the application can instantly send and / or call the doctor / trainer. In this system design based on the Internet of Things, the NodeMCU 12E board including ESP8266 Wi-Fi module, knee pad / elbow pad, Flex sensor were used.
聪明的运动是可靠的和激励的活动,减少受伤的可能性,并改善肌肉骨骼系统。当它无意识地运动时,它可能会对她/他的身体造成伤害或减缓运动的发展。本研究旨在研究骨科患者和运动员。由于开发的算法和设备,主要主题是在个人限制内按照给定的计划正确地做练习。根据使用目的,根据医生或教练计划的程序,当一个人(在佩戴肘部/膝盖支架后)以所需的程度完成所需的动作时,系统会发出通知。这个人从这个警报中了解到动作已经成功完成。这些过程可以同时存储在ThingSpeak云平台上,并通过无线网络在线性图上进行监控。有了开发的移动应用程序,人们可以立即看到运动的角度,应用程序可以立即发送和/或呼叫医生/教练。在本次基于物联网的系统设计中,采用了NodeMCU 12E板,包括ESP8266 Wi-Fi模块、膝垫/肘垫、Flex传感器。
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引用次数: 0
Deep learning to distinguish COVID-19 from other lung infections, pleural diseases, and lung tumors 通过深度学习将COVID-19与其他肺部感染、胸膜疾病和肺部肿瘤区分开来
Pub Date : 2020-11-19 DOI: 10.1109/TIPTEKNO50054.2020.9299215
Ali Serener, Sertan Serte
COVID-19 is a highly infectious respiratory disease caused by severe acute respiratory syndrome coronavirus 2. It can lead to cough and fever and in some cases severe pneumonia. It is generally detected by reverse-transcription polymerase chain reaction and computed tomography scans. However, as it is a lung disease, it has common symptoms with other respiratory diseases. This necessitates us to carefully differentiate COVID-19 from such diseases during the diagnosis. This work aims to do that with the help of several deep learning architectures and chest radiographs. It specifically focuses on differentiating COVID-19 from pneumonia, pleural effusion and lung mass. During this analysis, it is shown that we can differentiate COVID-19 from other respiratory diseases using various deep learning architectures. It is further shown that ResNet-18 architecture produces the best overall performance in three scenarios of experiments.
COVID-19是由严重急性呼吸综合征冠状病毒2引起的高度传染性呼吸道疾病。它会导致咳嗽和发烧,在某些情况下还会导致严重的肺炎。通常通过逆转录聚合酶链反应和计算机断层扫描检测。然而,由于它是一种肺部疾病,它与其他呼吸系统疾病有共同的症状。因此,必须在诊断过程中仔细区分COVID-19与此类疾病。这项工作的目的是在几个深度学习架构和胸部x光片的帮助下做到这一点。它特别侧重于区分COVID-19与肺炎、胸腔积液和肺肿块。在分析过程中,我们可以使用各种深度学习架构将COVID-19与其他呼吸道疾病区分开来。进一步表明,在三种实验场景下,ResNet-18架构的综合性能最好。
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引用次数: 6
Investigation of the Electromagnetic Dosimetry Characteristics of a 4 × 4 MIMO Antenna for WLAN Applications 无线局域网用4 × 4 MIMO天线电磁剂量学特性研究
Pub Date : 2020-11-19 DOI: 10.1109/TIPTEKNO50054.2020.9299283
K. Ateş, Can Yeter, ve Şükrü Özen
With the development of new generation communication systems, antenna technologies used in these areas and their effects on human health are also examined. In this study, a 4×4 MIMO antenna was designed for IEEE 802.11a applications through the finite element method (FEM) based electromagnetic simulation software. Also, its dosimetric effects on tissue were investigated. The proposed antenna includes four antennas operating at 5 GHz. It was designed on a 74 mm ×130 mm dielectric material with a frame height of 5 mm to meet the trend of current phones. The SAR distribution in the head and hand model caused by the antenna model were obtained as 1.4 W/kg and 0.7 W/kg for 1 gr average tissue, respectively.
随着新一代通信系统的发展,在这些领域使用的天线技术及其对人类健康的影响也进行了研究。本研究通过基于有限元法(FEM)的电磁仿真软件,为IEEE 802.11a应用设计了一种4×4 MIMO天线。并对其对组织的剂量效应进行了研究。该天线包括4个工作频率为5ghz的天线。它是在74毫米×130毫米的介电材料上设计的,框架高度为5毫米,以满足当前手机的趋势。天线模型在头部和手部模型中的SAR分布分别为1.4 W/kg和0.7 W/kg。
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引用次数: 0
On Visualization and Quantification of Lesion Margin in CT Liver Images 肝脏CT图像病灶边缘的可视化与定量研究
Pub Date : 2020-11-19 DOI: 10.1109/TIPTEKNO50054.2020.9299219
S. Arıca, Tuğçe Sena Altuntaş, G. Erbay
Cancer is the one of the leading causes of death worldwide, and cancer incidence increases every year. The analysis of lesion margin is quite important to diagnose malignant and benign masses and to detect the presence and the stage of tumor invasion in case of cancer. Accordingly, the aim of the study is to visualize and quantify margin of lesions on radiological images by means of a digital computer. In this study, computed tomography (CT) images of liver have been employed for analysis because the liver has crucial tasks in our body and liver cancer-related deaths is ranked as the forth among the cancer-related deaths. The proposed method consisted of four main steps: image cropping and smoothing, specification of target lesion, the boundary detection of target lesion, and visualization and quantification of margin. First, the images were converted to gray scale. The blank regions surrounding the liver in the CT images were removed before specification of target lesion, and further were smoothed with a bilateral filter. Next, the target region was specified roughly by drawing it manually. The boundary of lesion was more precisely determined with the active contour method employing the sketched borderline as the initial curve. Next, the properties of the target region: the centroid, major axis length, and the orientation values were computed. The intensities along a line passing through the center of the tumor were obtained for eighteen different rotation angles. A pulse model was fit to each of the intensity signal corresponding to a rotation. Then, the intensity change, margin sharpness and width were acquired from the pulse approximation associated to each rotation angle. The level difference provided the intensity change, the slope of edges gave the margin sharpness, and distance between the start and end points of the pulse edge represented margin width. Besides, the inner (core) and outer diameter with respect to angle were also displayed.
癌症是世界范围内死亡的主要原因之一,癌症发病率每年都在增加。病灶边缘的分析对于诊断恶性肿块和良性肿块,判断肿瘤是否存在及侵袭分期具有重要意义。因此,本研究的目的是通过数字计算机在放射图像上可视化和量化病灶的边缘。在本研究中,肝脏的计算机断层扫描(CT)图像被用于分析,因为肝脏在我们的身体中起着至关重要的作用,肝癌相关死亡在癌症相关死亡中排名第四。该方法包括图像裁剪与平滑、目标病灶指定、目标病灶边界检测、边缘可视化与量化四个主要步骤。首先,将图像转换为灰度。在确定目标病灶之前,先去除CT图像中肝脏周围的空白区域,然后用双侧滤波器进行平滑处理。接下来,通过手工绘制粗略指定目标区域。活动轮廓法以绘制的轮廓线为初始曲线,更精确地确定病灶的边界。接下来,计算目标区域的属性:质心、长轴长度和方向值。在18个不同的旋转角度下,获得沿一条穿过肿瘤中心的线的强度。对每一个旋转对应的强度信号进行脉冲模型拟合。然后,通过与每个旋转角度相关联的脉冲近似,获得光强变化、边缘锐度和宽度;等高差提供了强度变化,边缘的斜率给出了边缘锐度,脉冲边缘的起始点和结束点之间的距离表示边缘宽度。此外,还显示了内(芯)外径与角度的关系。
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引用次数: 0
期刊
2020 Medical Technologies Congress (TIPTEKNO)
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