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2020 Medical Technologies Congress (TIPTEKNO)最新文献

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Synchrosqueezing Transform in Biomedical Applications: A mini review 同步压缩变换在生物医学中的应用综述
Pub Date : 2020-11-19 DOI: 10.1109/TIPTEKNO50054.2020.9299225
Duygu Degirmenci, Melike Yalcin, Mehmet Akif Ozdemir, A. Akan
Time-frequency representation (TFR) provides a good analysis for periodic signals; however, they are insufficient for nonstationary signals. The synchrosqueezing transform (SST) provides a strong analysis of nonstationary signals. The signal has different synchrosqueezing transformations that are implemented using different TFR. This paper provides a review of the different SST methods implemented using different TFR available in the literature, a comparison of these, and their use with different techniques in biomedical signal processing applications. Adding different techniques to the applied SST method affects the signal processing and classification ability of the selected SST method.
时频表示(TFR)对周期信号提供了很好的分析;然而,它们对于非平稳信号是不够的。同步压缩变换(SST)为非平稳信号的分析提供了强有力的手段。信号具有使用不同TFR实现的不同同步压缩变换。本文综述了文献中使用不同TFR实现的不同SST方法,并对这些方法进行了比较,以及它们与不同技术在生物医学信号处理应用中的应用。在已应用的海表温度方法中加入不同的技术会影响所选海表温度方法的信号处理和分类能力。
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引用次数: 3
Neuronal Synchronization and The Sparseness of The Cortico-cortical Connections 神经元同步性和皮质-皮质连接的稀疏性
Pub Date : 2020-11-19 DOI: 10.1109/TIPTEKNO50054.2020.9299299
S. Kbah, N. Sengor
The effect of network connections on the synchronization is an area of interest in different disciplines. Several well-known methods have been developed as Kuramoto model. Recently, the relations between synchronization in the cortex and cognitive processes as selective attention, perception begin to draw attention in computational neuroscience. Also, there are works focusing on the relation between neurodegenerative diseases and synchronization in the cortex. Here, we focused on the role of connection sparseness in the cortex. To investigate the effect of sparseness, we built networks inspired by the structure of the cortex using Izhikevich Neuron model.
网络连接对同步的影响是不同学科感兴趣的领域。许多著名的方法都被发展为Kuramoto模型。近年来,皮层同步与选择性注意、知觉等认知过程的关系开始引起计算神经科学的关注。此外,也有工作集中在神经退行性疾病和皮层同步之间的关系。在这里,我们关注的是连接稀疏在大脑皮层中的作用。为了研究稀疏性的影响,我们利用Izhikevich神经元模型建立了受皮层结构启发的网络。
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引用次数: 0
Digital Filter Design Based on ARDUINO and Its Applications 基于ARDUINO的数字滤波器设计及其应用
Pub Date : 2020-11-19 DOI: 10.1109/TIPTEKNO50054.2020.9299311
Muharrem Çelebi
Nowadays, due to the rapid development of digital platforms, digital signal processing has become realizable into small size processors. The purpose of this study is to test the filtering process on both PC-based platform and embedded system. The first goal of this study is to compare the results of the filtering process obtained in MATLAB and ARDUINO environments. For the second purpose, filtering process will be tried in real-time on ARDUINO platform with the produced filter coefficients. Findings obtained as a result of the study are presented and discussed.
如今,由于数字平台的快速发展,数字信号处理已经可以用小尺寸的处理器来实现。本研究的目的是在pc平台和嵌入式系统上测试过滤过程。本研究的第一个目标是比较MATLAB和ARDUINO环境下滤波过程的结果。对于第二个目的,将在ARDUINO平台上使用生成的滤波系数实时尝试滤波过程。本文提出并讨论了研究结果。
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引用次数: 1
Multiclass Classification of Brain Cancer with Machine Learning Algorithms 基于机器学习算法的脑癌多类分类
Pub Date : 2020-11-19 DOI: 10.1109/TIPTEKNO50054.2020.9299233
Begüm Erkal, S. Başak, Alper Çiloğlu, Duygu Dede Sener
Brain cancer is one the most important disease to be treated all around the world. Classification of brain cancer using machine learning techniques has been widely studied by researchers. Microarray gene expression data are commonly used medical data to get observable results in this manner. In this study, multiclass classification of brain cancer is aimed by using different machine learning approaches. Some preprocessing methods were applied to get improved results. According to the result, feature selection has greatly affected the overall performance of each method in terms of overall accuracy and per class accuracy. Experimental results show that Multilayer Perceptron (MP) method has higher accuracy rate compared with other machine learning methods.
脑癌是全世界最需要治疗的疾病之一。使用机器学习技术对脑癌进行分类已经被研究人员广泛研究。微阵列基因表达数据是常用的医学数据,以这种方式获得可观察的结果。在本研究中,通过使用不同的机器学习方法,对脑癌进行多类分类。采用了一些预处理方法,得到了较好的结果。结果表明,特征选择对各方法的总体准确率和每类准确率都有较大的影响。实验结果表明,与其他机器学习方法相比,多层感知器(Multilayer Perceptron, MP)方法具有更高的准确率。
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引用次数: 5
Investigation of Temperature Effects Produced by an Epilation Device Within Agar Phantom 琼脂体中脱毛装置产生的温度效应的研究
Pub Date : 2020-11-19 DOI: 10.1109/TIPTEKNO50054.2020.9299265
H. Durmuş, Emel Çetin Ari, B. Karaböce, MirHasan Seyitsoy
In this study, the temperature effects created by the IPL light source (epilation device) applied by a commercial epilation device at regular intervals on four thermocouples placed 15 mm inside the agar phantom were investigated at five different power levels designed for different skin tones of the device. The determined temperatures have been found to be safe for human use.
在这项研究中,IPL光源(脱毛装置)通过商业脱毛装置在放置在琼脂体内15mm的四个热电偶上以固定间隔施加的温度效应,研究了针对该装置不同肤色设计的五种不同功率水平。确定的温度已被发现对人类使用是安全的。
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引用次数: 0
The Effect of Zinc Oxide Nanoparticles in Antibacterial Photothermal Therapy against MRSA 氧化锌纳米颗粒在MRSA抗菌光热治疗中的作用
Pub Date : 2020-11-19 DOI: 10.1109/TIPTEKNO50054.2020.9299253
B. Erk, Öykü Kabar, Hilal Er, Emel Bakay, Yeşim BÜYÜKSöKMEN, D. Karaman, N. Topaloglu
The discovery of the antibiotics is considered as a major development for the medical world from past to present. However, today due to the unnecessary and wrong use of antibiotics, most pathogenic bacteria have gained resistance to them. Methicillin Resistant Staphylococcus aureus (MRSA), one of the most common types of drug resistant bacteria, causes serious diseases such as hospital infections, and it is difficult to treat the disease with its resistance mechanism. Therefore, new searches for treatment have emerged to prevent infections caused by drug resistant bacteria. One of these new alternative treatments is antibacterial photothermal therapy, which will be supported by the use of nanoparticles in photothermal therapy. In this study, photothermal therapy was performed using zinc oxide (ZnO) nanoparticles which are known to have an antibacterial effect. ZnO concentrations for the applications performed were 100 ×g/ml and 250 ×g/ml. Light applications were carried out with a diode laser with 808-nm of wavelength using various output powers (1, 2, and 2.3 W) and energy densities (42.3, 100, 250, and 600 J/cm2) in the presence of both determined concentrations. The most effective result was more than 99.99% bacterial cell death when the concentration of 250 ×g/ml ZnO was applied with 2.3 W output power and 600 J/cm2 energy density. As a result of this study, it is thought that photothermal therapy in the presence of ZnO nanoparticles has great promise in the treatment of infections caused by antibiotic resistant strains when appropriate parameters are provided.
抗生素的发现被认为是从古至今医学界的一个重大发展。然而,今天由于不必要和错误地使用抗生素,大多数致病菌对它们产生了耐药性。耐甲氧西林金黄色葡萄球菌(Methicillin Resistant Staphylococcus aureus, MRSA)是最常见的耐药细菌之一,可引起医院感染等严重疾病,其耐药机制使其难以治疗。因此,人们开始寻找新的治疗方法来预防耐药细菌引起的感染。其中一种新的替代疗法是抗菌光热疗法,这将得到纳米粒子在光热疗法中的应用的支持。在这项研究中,使用氧化锌纳米粒子进行光热治疗,氧化锌纳米粒子已知具有抗菌作用。ZnO的应用浓度分别为100 ×g/ml和250 ×g/ml。在两种确定的浓度下,使用波长为808 nm的二极管激光器进行光应用,使用不同的输出功率(1、2和2.3 W)和能量密度(42.3、100、250和600 J/cm2)。当ZnO浓度为250 ×g/ml,输出功率为2.3 W,能量密度为600 J/cm2时,细菌细胞死亡率达到99.99%以上。由于本研究的结果,认为在提供适当参数的情况下,ZnO纳米颗粒存在的光热疗法在治疗抗生素耐药菌株引起的感染方面具有很大的前景。
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引用次数: 0
Determination of the Effect of Glycosaminoglycan Mimetic Peptide Hydrogels on Cell Viability for Cartilage Tissue Engineering Applications 测定糖胺聚糖模拟肽水凝胶对软骨组织工程中细胞活力的影响
Pub Date : 2020-11-19 DOI: 10.1109/TIPTEKNO50054.2020.9299263
Gülşah Sunal, Günnur Onak, Oğuzhan Gökmen, Ilayda Namli, O. Karaman
Cartilage is a tissue type that doesn’t have blood vessels, neural networks and lymphatic vessels. Regeneration of the cartilage tissue is limited due to the small number of cells in the articular cartilage, low vascularization and low cell migration to the damage site. Biomaterial scaffolds are used for regeneration of cartilage since the cartilage needs structural and metabolic support in case of any damage. Mimicking the network structure of the natural cartilage is extremely important and hydrogels are good candidates for cartilage tissue engineering due to 3-D structure and the high-water holding capacity similar to the natural tissue. Also, biomimetic self-assembling peptides (SAP) can self-assemble with physiological conditions and form SAP hydrogels. Glycosaminoglycan (GAG) is crucial components of natural cartilage matrix, they are negatively charged chains, and they maintain the mechanical properties of tissue. In this study, it was develop GAG mimetic SAP hydrogels that can mimic original cartilage, and to determine the effect of these peptide hydrogels on cell viability and cell proliferation. SAP hydrogel structures were successfully produced by functionalization of SAP with GAG mimetic peptide epitope, and effect of these hydrogels on cell viability was evaluated by cell culture methods in this work.
软骨是一种没有血管、神经网络和淋巴管的组织。由于关节软骨中的细胞数量少,血管化程度低,细胞向损伤部位的迁移程度低,软骨组织的再生受到限制。生物材料支架用于软骨的再生,因为软骨在受到损伤时需要结构和代谢的支持。模拟天然软骨的网状结构是非常重要的,水凝胶具有类似于天然组织的三维结构和高持水能力,是软骨组织工程的良好候选材料。此外,仿生自组装肽(SAP)可以在生理条件下自组装并形成SAP水凝胶。糖胺聚糖(GAG)是天然软骨基质的重要组成部分,它们是带负电荷的链,维持组织的力学性能。本研究开发了能够模拟原始软骨的GAG模拟SAP水凝胶,并测定了这些肽水凝胶对细胞活力和细胞增殖的影响。通过对SAP进行GAG模拟肽表位功能化,制备了SAP水凝胶结构,并通过细胞培养的方法对SAP水凝胶对细胞活力的影响进行了评价。
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引用次数: 0
Amputee Electromyography Signal Classification Using Convolutional Neural Network 基于卷积神经网络的截肢者肌电信号分类
Pub Date : 2020-11-19 DOI: 10.1109/TIPTEKNO50054.2020.9299236
Fatih Onay, A. Mert
The classification of EMG signals for the amputees is important to develop a powered-prosthetic that is capable of replacing with lost limbs. The EMG signals collected from residual limbs reduce the classification accuracy due to muscle movements that cannot be realized properly. In thıs study, classification performance is aimed to be increased by combining CNN with root mean square (RMS) and waveform length (WL) that are used in analysis of EMG signals successfully. The features such as RMS and WL extracted from EMG signals for the classification of six hand movements at the low, medium, and high force levels were applied to CNN input, and classification results were compared with nearest neighbour and linear discriminant analysis.
被截肢者肌电信号的分类对于开发一种能够替代失去肢体的动力假肢非常重要。残肢肌电信号采集过程中由于肌肉运动无法正常实现,导致分类精度降低。在thıs研究中,通过将CNN与肌电信号分析中使用的均方根(RMS)和波形长度(WL)成功结合,以提高分类性能。将肌电信号提取的RMS、WL等特征用于低、中、高三种力水平下的手部运动分类,并将分类结果与最近邻分析和线性判别分析进行比较。
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引用次数: 0
Classification of Abnormal Respiratory Sounds Using Machine Learning Techniques 使用机器学习技术分类异常呼吸音
Pub Date : 2020-11-19 DOI: 10.1109/TIPTEKNO50054.2020.9299294
Hüseyin Cihad Güler, V. Yildiz, U. Baysal, ve Funda B. Cinyol, D. Köksal, E. Babaoğlu, S. Sarınç Ulaşlı
Lung sounds can vary according to various respiratory diseases of the person. Specialist physicians use these sound data to make a diagnosis. Diagnostic success varies according to the physician’s experience. computer-aided diagnostic systems can help physicians in this regard. In this study, disease diagnosis system was developed by using lung sound data obtained by auscultation method. In experimental studies, various machine learning methods have been tried on 20 normal, 20 ral and 20 rhoncus sound data taken from 60 patients. In addition, the data set was tripled with two different artificial data generation methods. The results obtained by applying k- Nearest Neighbor (kNN), Support Vector Machine (SVM), Naive Bayes, Decision Tree and Random Forest Classifier to all data obtained by real data set and artificial data production are presented. A 95% accuracy value was obtained with 10 cross- validation using the Naive Bayes classification method. In the results obtained after artificial data production, an accuracy value of 94% was obtained with 10 cross-validation with the kNN method.
肺音可以根据人的各种呼吸系统疾病而变化。专科医生利用这些可靠的数据进行诊断。诊断的成功与否取决于医生的经验。计算机辅助诊断系统可以在这方面帮助医生。本研究利用听诊法获得的肺音数据,开发疾病诊断系统。在实验研究中,对来自60名患者的20个正常声音、20个正常声音和20个低音声音数据进行了各种机器学习方法的尝试。此外,用两种不同的人工数据生成方法对数据集进行了三倍的处理。给出了将k-最近邻(kNN)、支持向量机(SVM)、朴素贝叶斯(Naive Bayes)、决策树(Decision Tree)和随机森林分类器(Random Forest Classifier)应用于实际数据集和人工数据生成得到的所有数据的结果。采用朴素贝叶斯分类方法进行10次交叉验证,准确率达到95%。在人工数据生成后得到的结果中,采用kNN方法进行10次交叉验证,准确率达到94%。
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引用次数: 2
Morphological Classification of Low Quality Sperm Images Using Deep Learning Networks 基于深度学习网络的低质量精子图像形态学分类
Pub Date : 2020-11-19 DOI: 10.1109/TIPTEKNO50054.2020.9299318
Mecit Yüzkat, Hamza Osman Ilhan, N. Aydin
The fertility of men and women are examined separately in the diagnosis of infertility. Clinical studies have shown that male infertility rate has a high rate of 25-30% in general diagnosis. Sperm concentration, motility and morphological abnormality are evaluated in male based infertility. In morphological analysis, sperm images should be obtained in detail to obtain objective results. However, the usage of low quality video camera or vibrations occurred in camera module causes to obtain low quality images. In this study, in order to increase the classification performance of the SCIAN-Morpho dataset with low quality sperm images, firstly interpolation methods were applied to increase the data quality. Then, data augmentation techniques have been applied for the data imbalance problem. In the classification phase, pre-trained convolutional neural networks were applied. As a result of the classification, 62% accuracy, 85% precision and 75% sensitivity were obtained by using the VGG-19 networks with the data augmentation and interpolation techniques.
在诊断不孕症时,应分别检查男性和女性的生育能力。临床研究表明,男性不育症的一般诊断率高达25-30%。精子浓度、活力和形态异常在男性不育中被评估。在形态学分析中,需要获得详细的精子图像,以获得客观的结果。然而,使用低质量的摄像机或摄像机模块发生振动会导致图像质量低。本研究为了提高SCIAN-Morpho数据集对低质量精子图像的分类性能,首先采用插值方法提高数据质量;然后,将数据增强技术应用于数据不平衡问题。在分类阶段,使用预训练的卷积神经网络。结合数据增强和插值技术,VGG-19网络的分类准确率为62%,精密度为85%,灵敏度为75%。
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引用次数: 2
期刊
2020 Medical Technologies Congress (TIPTEKNO)
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