J. Kovacic, A. Dhar, Andrew R H Shepherd, I. Popa, A. Chung
Erectile dysfunction is more common than realised and can be the first indication of systemic disease. Penile prosthesis is a low‐risk intervention with high patient satisfaction, previously deemed an endstage form of management. However, improvements in the devices and a recent American Association of Urology recommendation could change that.
{"title":"Penile prosthesis no longer intervention of last resort for erectile dysfunction?","authors":"J. Kovacic, A. Dhar, Andrew R H Shepherd, I. Popa, A. Chung","doi":"10.1002/tre.912","DOIUrl":"https://doi.org/10.1002/tre.912","url":null,"abstract":"Erectile dysfunction is more common than realised and can be the first indication of systemic disease. Penile prosthesis is a low‐risk intervention with high patient satisfaction, previously deemed an endstage form of management. However, improvements in the devices and a recent American Association of Urology recommendation could change that.","PeriodicalId":42819,"journal":{"name":"Trends in Urology & Mens Health","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75256300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Immune checkpoint inhibitors (ICIs) have had a significant impact on the prognosis of people with a wide range of tumours. Melanoma in particular is one of the malignancies for which immunotherapy can achieve excellent outcomes in the adjuvant and advanced settings. Here the authors discuss the use of ICIs and the benefits they can offer.
{"title":"How have immune checkpoint inhibitors transformed melanoma treatment?","authors":"A. Schmitt, J. Larkin","doi":"10.1002/tre.910","DOIUrl":"https://doi.org/10.1002/tre.910","url":null,"abstract":"Immune checkpoint inhibitors (ICIs) have had a significant impact on the prognosis of people with a wide range of tumours. Melanoma in particular is one of the malignancies for which immunotherapy can achieve excellent outcomes in the adjuvant and advanced settings. Here the authors discuss the use of ICIs and the benefits they can offer.","PeriodicalId":42819,"journal":{"name":"Trends in Urology & Mens Health","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84778633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pancreatic cancer carries a very poor prognosis, with five‐year survival currently approaching 10%. Late presentation, lack of effective treatment options and a tumour microenvironment that subverts immune mechanisms are some of the reasons behind this. Here the authors discuss how advances in our understanding of tumour biology, identification and surveillance of high‐risk groups, improvements in surgical outcomes and the availability of new chemotherapeutic options give us grounds for optimism.
{"title":"Pancreatic cancer: a glimmer of hope","authors":"S. Nagendram, S. Bhattacharya","doi":"10.1002/tre.904","DOIUrl":"https://doi.org/10.1002/tre.904","url":null,"abstract":"Pancreatic cancer carries a very poor prognosis, with five‐year survival currently approaching 10%. Late presentation, lack of effective treatment options and a tumour microenvironment that subverts immune mechanisms are some of the reasons behind this. Here the authors discuss how advances in our understanding of tumour biology, identification and surveillance of high‐risk groups, improvements in surgical outcomes and the availability of new chemotherapeutic options give us grounds for optimism.","PeriodicalId":42819,"journal":{"name":"Trends in Urology & Mens Health","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75503266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fetal ultrasound can identify babies who are at risk of developing renal failure. However, renal damage before birth is difficult to reverse and end‐stage renal failure may not be preventable.
胎儿超声可以识别出有肾衰竭风险的婴儿。然而，出生前的肾损害是难以逆转的，终末期肾衰竭可能无法预防。
{"title":"Congenital urinary obstruction and renal failure: has fetal ultrasound improved the prognosis?","authors":"Christopher Woodhouse","doi":"10.1002/tre.905","DOIUrl":"https://doi.org/10.1002/tre.905","url":null,"abstract":"Fetal ultrasound can identify babies who are at risk of developing renal failure. However, renal damage before birth is difficult to reverse and end‐stage renal failure may not be preventable.","PeriodicalId":42819,"journal":{"name":"Trends in Urology & Mens Health","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83849456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Recent events have left the NHS starved of funds and the immediate future does not look too bright financially either. The organisation is also suffering from low staff morale and burnout of its workforce along with ever‐increasing demand. Indeed all the pressures now facing the NHS point towards a need for far‐reaching reform.
{"title":"Is it time to properly examine NHS reform?","authors":"S. Fleming","doi":"10.1002/tre.909","DOIUrl":"https://doi.org/10.1002/tre.909","url":null,"abstract":"Recent events have left the NHS starved of funds and the immediate future does not look too bright financially either. The organisation is also suffering from low staff morale and burnout of its workforce along with ever‐increasing demand. Indeed all the pressures now facing the NHS point towards a need for far‐reaching reform.","PeriodicalId":42819,"journal":{"name":"Trends in Urology & Mens Health","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84777745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this editorial, Professor Roger Kirby, Editor‐in‐Chief of Trends in Urology and Men's Health, reflects on the reasons for and consequences of increasing numbers of doctors leaving the NHS.
{"title":"Doctors are leaving!","authors":"R. Kirby","doi":"10.1002/tre.906","DOIUrl":"https://doi.org/10.1002/tre.906","url":null,"abstract":"In this editorial, Professor Roger Kirby, Editor‐in‐Chief of Trends in Urology and Men's Health, reflects on the reasons for and consequences of increasing numbers of doctors leaving the NHS.","PeriodicalId":42819,"journal":{"name":"Trends in Urology & Mens Health","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89657761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Professor Mike Kirby, Editor of Trends in Urology and Men's Health, picks some interesting recent papers and highlights the ‘take‐home’ messages.
《泌尿学与男性健康趋势》的编辑迈克·柯比教授挑选了一些有趣的近期论文，并强调了“带回家”的信息。
{"title":"Journal watch","authors":"Mike Kirby","doi":"10.1002/tre.907","DOIUrl":"https://doi.org/10.1002/tre.907","url":null,"abstract":"Professor Mike Kirby, Editor of Trends in Urology and Men's Health, picks some interesting recent papers and highlights the ‘take‐home’ messages.","PeriodicalId":42819,"journal":{"name":"Trends in Urology & Mens Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135074930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Conti, L. Pellegrini, M. Riaz, D. Mpavaenda, Alex Sim, N. Fineberg
Obsessive‐compulsive disorder (OCD) commonly affects males and can manifest with a range of urological symptoms directly linked to the content of the OCD. In Part 1 of this article, the authors discussed the recognition and diagnosis of OCD. In Part 2 here, they consider its treatment and related sexual dysfunction.
{"title":"Obsessive‐compulsive disorder and men's health. Part 2: Treatment and related sexual dysfunction","authors":"D. Conti, L. Pellegrini, M. Riaz, D. Mpavaenda, Alex Sim, N. Fineberg","doi":"10.1002/tre.908","DOIUrl":"https://doi.org/10.1002/tre.908","url":null,"abstract":"Obsessive‐compulsive disorder (OCD) commonly affects males and can manifest with a range of urological symptoms directly linked to the content of the OCD. In Part 1 of this article, the authors discussed the recognition and diagnosis of OCD. In Part 2 here, they consider its treatment and related sexual dysfunction.","PeriodicalId":42819,"journal":{"name":"Trends in Urology & Mens Health","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78835627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Pizzol, G. F. López Sánchez, P. Ilie, A. Bertoldo, M. Trott, M. Tully, Jason J. Wilson, N. Veronese, P. Soysal, A. Carrie, S. Ippoliti, Luke Pratsides, Sam Shah, A. Koyanagi, L. Butler, Y. Barnett, Christopher Parris, Rosie K. Lindsay, Lee Smith
Premature ejaculation is a common male condition worldwide with prevalence estimates varying from 30% to 85%. Owing to the lack of a clear definition and a clear understanding of the potentially multifactorial pathophysiology, treatment remains challenging. The aim of this systematic review was to evaluate the non‐pharmacological treatment modalities for PE to inform clinical practice and patients.
{"title":"Non‐pharmacological approaches for treatment of premature ejaculation: a systematic review","authors":"D. Pizzol, G. F. López Sánchez, P. Ilie, A. Bertoldo, M. Trott, M. Tully, Jason J. Wilson, N. Veronese, P. Soysal, A. Carrie, S. Ippoliti, Luke Pratsides, Sam Shah, A. Koyanagi, L. Butler, Y. Barnett, Christopher Parris, Rosie K. Lindsay, Lee Smith","doi":"10.1002/tre.903","DOIUrl":"https://doi.org/10.1002/tre.903","url":null,"abstract":"Premature ejaculation is a common male condition worldwide with prevalence estimates varying from 30% to 85%. Owing to the lack of a clear definition and a clear understanding of the potentially multifactorial pathophysiology, treatment remains challenging. The aim of this systematic review was to evaluate the non‐pharmacological treatment modalities for PE to inform clinical practice and patients.","PeriodicalId":42819,"journal":{"name":"Trends in Urology & Mens Health","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85462543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
As medical technology develops, cancer can be detected sooner and potentially be treated more effectively. However, the benefits of early detection are not clear. Here the authors discuss whether early detection of kidney cancer is leading to overtreatment of some patients and how newer diagnostic techniques may help improve patient‐centred management of the disease.
{"title":"Incidental small renal tumours: are we performing unnecessary surgery?","authors":"H. Warren, M. Tran","doi":"10.1002/tre.900","DOIUrl":"https://doi.org/10.1002/tre.900","url":null,"abstract":"As medical technology develops, cancer can be detected sooner and potentially be treated more effectively. However, the benefits of early detection are not clear. Here the authors discuss whether early detection of kidney cancer is leading to overtreatment of some patients and how newer diagnostic techniques may help improve patient‐centred management of the disease.","PeriodicalId":42819,"journal":{"name":"Trends in Urology & Mens Health","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88604668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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