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Internet of Things—A Novel Innovation in Dentistry 物联网——牙科领域的新创新
IF 0.7 Pub Date : 2020-12-25 DOI: 10.1177/2320206820980248
Balaji Ganesh S, K. Sugumar
We are living in an era where medicine and dentistry are evolving. Dental caries, tooth malalignment and periodontal diseases are being encountered by dental specialists in their daily practices. New digital technologies are emerging in dentistry for diagnostic and treatment purposes. Digitization enhances our efficiency and saves time. One of the recent smart technological innovation in healthcare field is the Internet of Things (IoT). IoT consists of a network of physical gadgets embedded with instrumentation electronics, mounted chips and sensors. Through cloud web technology and internet connectivity, the required data collection is enabled. Acquired data is then exchanged to the doctors and analysis is done. This review article deals about the concept of IoT and its futuristic role in dentistry. The review article is based on the electronic searching and analysis of various international and national publications on the IoT concept in dentistry, medicine and biomedical engineering. A bench marking analysis was made on various applications, pros and cons of IoT in dentistry. IoT will play a paramount role in the clinical advancement aspects of diagnosis and management of various oral diseases in the forthcoming decades.
我们生活在一个医学和牙科不断发展的时代。牙科专家在日常工作中经常遇到蛀牙、牙齿不整齐和牙周病。新的数字技术正在出现在牙科诊断和治疗目的。数字化提高了我们的效率,节省了时间。物联网(IoT)是近年来医疗保健领域的智能技术创新之一。物联网由嵌入仪器电子设备、安装芯片和传感器的物理设备网络组成。通过云网络技术和互联网连接,所需的数据收集得以实现。然后将获得的数据交换给医生并进行分析。这篇综述文章涉及物联网的概念及其在牙科中的未来作用。这篇综述文章是基于对牙科、医学和生物医学工程中物联网概念的各种国际和国内出版物的电子检索和分析。对物联网在牙科领域的各种应用、利弊进行了基准分析。在未来几十年,物联网将在各种口腔疾病的诊断和管理的临床进步方面发挥至关重要的作用。
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引用次数: 3
Remineralization Potential and Shear Bond Strength of Surface Treated Hypomineralized Enamel in Bonding of Orthodontic Brackets: An In Vitro Study 表面处理过的低矿化牙釉质在正畸托槽粘接中的再矿化电位和剪切粘接强度的体外研究
IF 0.7 Pub Date : 2020-12-21 DOI: 10.1177/2320206820977734
E. Enan, M. Tawfik, R. Mehesen, S. Basha
Aim: To investigate the effect of different conditioning methods on remineralization potential of hypomineralized enamel and its shear bond strength (SBS) to orthodontic brackets. Materials and Methods: An in vitro study was conducted at Mansoura University, Egypt. Eighty premolars were collected and randomly classified into four groups (n = 20 each) as follows: Group 1. Control (sound teeth), Group 2. Demineralized, Group 3. Demineralized and treated with nanohydroxyapatite (nano-HA) varnish, Group 4. Demineralized and treated with casein phosphopeptide–amorphous calcium phosphate (CPP–ACP) paste. To detect the rate of remineralization on the surface of treated specimens, energy dispersive X-ray (EDX) analysis was used in conjunction with the scanning electron microscope (SEM). The SBS was measured with a universal testing machine. One-way ANOVA test was carried out to analyze differences between the tested groups. Result: SE micrographs of Group 3 and Group 4 specimens showed smoother and less porous enamel surface than that of the Group 2 specimens. EDX analysis showed highest calcium (Ca) (25.47%) and phosphorous (P) (12.76%) values for Group 4 while Group 2 showed the lowest Ca and P values (16.96%) and (10.20%), respectively (P < .001). Demineralized enamel showed lowest (3.70 MPa) SBS mean value compared to sound (10.69 MPa) and remineralized enamel (Group 3—9.90 MPa, Group 4—10.32 MPa) (P < .001). Conclusion: Nano-HA and CPP–ACP have equal remineralizing effect on hypomineralized enamel lesions and positive influence on SBS.
目的:探讨不同调理方法对低矿化牙釉质再矿化电位及其与托槽的剪切结合强度的影响。材料与方法:体外实验在埃及曼苏拉大学进行。收集前磨牙80颗,随机分为4组,每组20颗。对照组(健全牙),第二组。脱矿,第3族。用纳米羟基磷灰石(纳米ha)清漆进行脱矿处理,第4组。用酪蛋白磷酸肽-无定形磷酸钙(CPP-ACP)浆料进行脱矿处理。为了检测处理后试样表面的再矿化率,将能量色散x射线(EDX)分析与扫描电子显微镜(SEM)结合使用。SBS是用通用试验机测量的。采用单因素方差分析分析各组间差异。结果:实验组3和实验组4的牙釉质表面较实验组2光滑,釉质表面孔隙较少。EDX分析显示,组4的钙(Ca)和磷(P)含量最高(25.47%),磷(P)含量最高(12.76%),组2的钙(Ca)和磷(P)含量最低(16.96%),磷(P)含量最低(10.20%)(P < 0.001)。脱矿牙釉质的SBS平均值(3.70 MPa)低于正常牙釉质(10.69 MPa)和再矿牙釉质(3 ~ 9.90 MPa, 4 ~ 10.32 MPa) (P < 0.001)。结论:纳米ha与CPP-ACP对低矿化牙釉质病变有同等的再矿化作用,对SBS有积极影响。
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引用次数: 2
Comparison of Marginal Adaptation of Different Resin-Ceramic CAD/CAM Crowns: An In Vitro Study 不同树脂陶瓷CAD/CAM冠的边缘适应性比较
IF 0.7 Pub Date : 2020-12-21 DOI: 10.1177/2320206820975971
E. I. Oguz, M. Kılıçarslan, Merve Erdog˘ Özgür, K. Orhan, S. Shujaat
Aim: To compare the marginal adaptation of crowns fabricated by using three different resin-ceramic computer-aided design/computer-aided manufacturing (CAD/CAM) materials. Materials and Methods: Crowns fabricated from three different resin-ceramic CAD/CAM blocks, applied on a typodont premolar (#14), were tested with regard to marginal adaptation, in this in vitro study. The typodont maxillary first premolar was prepared to serve as the master die and digitized with an intraoral scanner. The same virtual crown design was used to fabricate all specimens. Forty-eight crowns were fabricated from the same virtual crown design using three different CAD/CAM resin-ceramic blocks as follows (n = 16): Lava Ultimate (LU), GC Cerasmart (GC), Vita Enamic (VE). Master die and crowns were scanned with a laboratory scanner and three-dimensional data were transferred into three-matic software. The software calculated the mean of the marginal discrepancy (MD) for each crown in negative and positive values, representing under and over estimation of the crown margin, respectively. A marginal discrepancy index (MDI) was obtained for each group using negative and positive MDs. All data were statistically analyzed using one-way analysis of variance and Tukey’s honest significance test (α = 0.05). Results: The analysis of variance showed no statistical differences between materials regarding the negative and positive MDs (P > .05). The MDI for LU was lower than GC and VE (P < .05). Conclusion: The marginal adaptation of different resin-ceramic materials was different with regard to MDI values. Nevertheless, the MD values of all groups were within the clinically acceptable range.
目的:比较三种不同树脂陶瓷计算机辅助设计/计算机辅助制造(CAD/CAM)材料制备冠体的边缘适应性。材料和方法:在这项体外研究中,由三种不同的树脂陶瓷CAD/CAM块制成的冠,应用于typodon前磨牙(#14),测试了边缘自适应。准备上颌第一前磨牙作为主模,用口内扫描仪进行数字化处理。采用相同的虚拟冠设计制作所有标本。采用三种不同的CAD/CAM树脂陶瓷块(n = 16): Lava Ultimate (LU), GC Cerasmart (GC), Vita Enamic (VE),采用相同的虚拟冠设计制作48个冠。用实验室扫描仪扫描主模和齿冠,并将三维数据传输到三维软件中。该软件计算出每个冠的边际差异(MD)的平均值为负值和正值,分别表示冠边缘的估计不足和高估。采用阴性和阳性MDs计算各组的边际差异指数(MDI)。所有数据采用单因素方差分析和Tukey’s honest显著性检验(α = 0.05)进行统计学分析。结果:经方差分析,材料间MDs阳性和阴性差异无统计学意义(P > 0.05)。LU组MDI低于GC组和VE组(P < 0.05)。结论:不同树脂陶瓷材料对MDI值的边际适应性不同。然而,所有组的MD值均在临床可接受范围内。
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引用次数: 1
Comparison of Autogenous Block Bone Graft and Screw Tent-Pole Techniques for Vertical Bone Augmentation in the Posterior Mandible: A Split-Mouth Randomized Controlled Study 自体块骨移植与螺钉-帐篷杆技术在后颌骨垂直骨增强中的比较:一项裂口随机对照研究
IF 0.7 Pub Date : 2020-12-21 DOI: 10.1177/2320206820976010
Gözde Işık, T. Günbay, Yig˘it Uyanıkgil, Hüseyin Kısaog˘lu, Meltem Özden Yüce
Aim: To evaluate the effect on vertical bone augmentation of the screw tent-pole technique using particulate allograft in combination with injectable platelet-rich fibrin, and to compare this with autogenous block bone graft. Materials and Methods: This split-mouth randomized controlled study involved patients with bilateral partial edentulism and vertical bone loss in the posterior mandible. In each patient, the control side was treated with autogenous block bone graft harvested from the mandibular ramus and, on the test side, the screw tent-pole technique was employed, using particulate allograft in combination with injectable platelet-rich fibrin. All augmented sites were covered by leukocyte and platelet-rich fibrin membrane. The primary outcome variable of this study was the radiographic changes to bone height 6 months after augmentation. The secondary outcome variables were the percentage of newly formed bone and the implant survival rate. The data were analyzed with a significance level of α = 0.05. Results: Of the 13 patients included, a total of 11 patients (7 females, 4 males; mean age 50.92) completed the study. The mean values of vertical bone gain were 1.72 ± 0.78 mm for the test group and 2.83 ± 0.89 mm for the control group, which constitutes a significant difference (P = .008). The percentage of newly formed bone was 18.08% ± 2.17% for the test group and 14.26% ± 1.76% for the control group. The difference between the groups was statistically significant (P < .001). The implant survival rates were 100% for both study groups. Conclusions: Based on the study results, screw tent-pole can be considered a feasible technique for bone augmentation. Further randomized studies will be necessary to fully evaluate vertical bone augmentation using the screw tent-pole technique, with different graft materials and with larger samples.
目的:评价颗粒异体骨移植联合可注射富血小板纤维蛋白对垂直骨增强的效果,并与自体块骨移植进行比较。材料与方法:本研究为双侧部分牙槽骨缺损及后颌骨垂直骨缺失患者的随机对照研究。在每个患者中,对照侧采用从下颌支采集的自体块骨移植物治疗,在试验侧采用螺钉帐篷杆技术,使用颗粒同种异体移植物结合可注射的富血小板纤维蛋白。所有增强部位均被白细胞和富血小板纤维蛋白膜覆盖。本研究的主要结局变量是增强后6个月骨高度的影像学变化。次要结果变量为新生骨百分比和种植体存活率。数据分析的显著性水平为α = 0.05。结果:纳入的13例患者中,共11例(女7例,男4例;平均年龄50.92岁)完成研究。试验组垂直骨长高平均值为1.72±0.78 mm,对照组为2.83±0.89 mm,差异有统计学意义(P = 0.008)。试验组新成骨率为18.08%±2.17%,对照组为14.26%±1.76%。两组间差异有统计学意义(P < 0.001)。两个研究组的种植体存活率均为100%。结论:基于本研究结果,螺钉帐篷杆可被认为是一种可行的骨增强技术。需要进一步的随机研究来充分评估使用螺钉帐篷杆技术、不同移植物材料和更大样本进行垂直骨增强的效果。
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引用次数: 7
Use of Quality-Adjusted Tooth Years as an Outcome Measure of Periodontal Treatment: A Quasi Experimental Study 使用质量调整牙龄作为牙周治疗的结果测量:一项准实验研究
IF 0.7 Pub Date : 2020-12-14 DOI: 10.1177/2320206820975990
T. Mohd-Dom, S. W. Puteh, Rasidah Ayob, M. Tennant, S. Aljunid
Aim: To develop a simple approach to estimate quality-adjusted tooth years of teeth (QATY) treated for periodontitis and determine gains in QATY after undergoing cause-related periodontal therapy (CRPT). Quality-adjusted life years (QALY) gained for these patients were also determined. Materials and Methods: Patients newly diagnosed with periodontitis (n = 165, 58.8% females, mean age 43.3 years) were recruited from periodontal specialist clinics. They received CRPT within a period of one year. We used the EuroQoL 5 Dimension (EQ-5D) and the Malaysian Oral Health Impact Profile (OHIP-14) indexes to measure changes in quality-of-life after one year of periodontal treatment. We then used these two scores to calculate their respective utilities and subsequently calculated QALY and QATY. Results: Proportions of deep periodontal sites (≥ 4 mm) decreased from 32.7% to 23.2% and patients gained an average of 0.3 mm of clinical attachment level per tooth at post-treatment follow-up. Improvements in means of OHIP-14 scores from 20.30 to 12.7 were consistent with changes in EQ-5D utilities from 0.81 to 0.91. Treated teeth gained 20.4 years for longevity while patients gained 17 QATYs. This is in line with the increase of 3.8 QALYs. Both treatment outcomes and clinical parameters were statistically significant at P < .0001. Conclusions: The method of estimating QATY using utilities derived from OHIP-14 combined with tooth life expectancy demonstrated that it may be used to measure effective treatment outcomes and is found to be consistent with improvements in QALY scores as calculated using EQ-5D-3L.
目的:建立一种简单的方法来评估牙周炎治疗后的牙齿质量调整牙龄(QATY),并确定接受原因相关牙周治疗(CRPT)后的QATY的收益。这些患者获得的质量调整生命年(QALY)也被确定。材料与方法:从牙周专科门诊招募新诊断为牙周炎的患者165例,女性58.8%,平均年龄43.3岁。他们在一年内接受了CRPT。我们使用EuroQoL 5维度(EQ-5D)和马来西亚口腔健康影响概况(OHIP-14)指数来衡量牙周治疗一年后生活质量的变化。然后,我们使用这两个分数来计算它们各自的效用,并随后计算QALY和QATY。结果:在治疗后随访中,深牙周部位(≥4 mm)的比例从32.7%下降到23.2%,患者每颗牙的临床附着水平平均增加0.3 mm。OHIP-14得分从20.30提高到12.7,EQ-5D效用从0.81提高到0.91。治疗后的牙齿寿命增加了20.4年,而患者的寿命增加了17个QATYs。这与3.8个qaly的增长是一致的。治疗结果和临床参数均有统计学意义,P < 0.0001。结论:使用OHIP-14衍生工具结合牙齿预期寿命估算QALY的方法表明,它可以用来衡量有效的治疗结果,并且发现与使用EQ-5D-3L计算的QALY评分的改善是一致的。
{"title":"Use of Quality-Adjusted Tooth Years as an Outcome Measure of Periodontal Treatment: A Quasi Experimental Study","authors":"T. Mohd-Dom, S. W. Puteh, Rasidah Ayob, M. Tennant, S. Aljunid","doi":"10.1177/2320206820975990","DOIUrl":"https://doi.org/10.1177/2320206820975990","url":null,"abstract":"Aim: To develop a simple approach to estimate quality-adjusted tooth years of teeth (QATY) treated for periodontitis and determine gains in QATY after undergoing cause-related periodontal therapy (CRPT). Quality-adjusted life years (QALY) gained for these patients were also determined. Materials and Methods: Patients newly diagnosed with periodontitis (n = 165, 58.8% females, mean age 43.3 years) were recruited from periodontal specialist clinics. They received CRPT within a period of one year. We used the EuroQoL 5 Dimension (EQ-5D) and the Malaysian Oral Health Impact Profile (OHIP-14) indexes to measure changes in quality-of-life after one year of periodontal treatment. We then used these two scores to calculate their respective utilities and subsequently calculated QALY and QATY. Results: Proportions of deep periodontal sites (≥ 4 mm) decreased from 32.7% to 23.2% and patients gained an average of 0.3 mm of clinical attachment level per tooth at post-treatment follow-up. Improvements in means of OHIP-14 scores from 20.30 to 12.7 were consistent with changes in EQ-5D utilities from 0.81 to 0.91. Treated teeth gained 20.4 years for longevity while patients gained 17 QATYs. This is in line with the increase of 3.8 QALYs. Both treatment outcomes and clinical parameters were statistically significant at P < .0001. Conclusions: The method of estimating QATY using utilities derived from OHIP-14 combined with tooth life expectancy demonstrated that it may be used to measure effective treatment outcomes and is found to be consistent with improvements in QALY scores as calculated using EQ-5D-3L.","PeriodicalId":43017,"journal":{"name":"Journal of Advanced Oral Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73361395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
An Innovative Meta-Systematic Review into the Landscape of Literature and the Concluding Evidence on the Quality of Life of Patients Using Two Implant Supported Mandibular Complete Denture Prosthesis 对双种植下颌全口义齿患者生活质量的文献景观和结论性证据进行创新性meta系统综述
IF 0.7 Pub Date : 2020-12-09 DOI: 10.1177/2320206820953992
V. Rajaraman, D. Nallaswamy, D. Ganapathy, V. Ashok
Aim: The aim of this systematic review is to analyze the existing evidence on the quality of life of patients completely edentulous in the mandible. Materials and Methods: A search questionnaire was formulated using population intervention comparison outcome (PICO) analysis, and a comprehensive search was initiated in PubMed Central, Medline, Cochrane, and Google Scholar databases for the related topics. Manuscripts published till December 2019 were included in this review. Out of the 63 articles obtained from searching all databases, 27 studies were excluded based on the title and abstract. Out of the remaining 36 studies, 12 were excluded based on the inclusion and exclusion criteria of our interest and 24 were included on the basis of core data. Results: One review author identified randomized trials meeting inclusion criteria for this review. Two review authors extracted data and assessed study quality. The oral health-related quality of life in completely edentulous mandibular patients wearing implant-supported overdentures was better when compared to conventional tissue-supported complete denture, and a minimum two implant-supported mandibular complete denture has sufficient improvement in oral health-related quality of life. Conclusion: There are about more than 170 reviews and clinical trials that have been published in support of the same for the past two decades. Thus, the clinicians may not be tempted in placing additional implants in well-formed mandibular edentulous ridges. To enhance the understanding of mandibular implant overdenture treatment, clinicians must scrutinize the existing evidence and formulate a protocol by striking a balance between efficient and evidence based treatment.
目的:本系统综述的目的是分析现有的证据对患者的生活质量在完全无牙的下颌骨。材料与方法:采用人口干预比较结果(PICO)分析编制检索问卷,并在PubMed Central、Medline、Cochrane和Google Scholar数据库中对相关主题进行全面检索。截至2019年12月发表的稿件纳入本综述。在检索所有数据库获得的63篇文章中,根据标题和摘要排除了27篇研究。在剩余的36项研究中,12项根据我们感兴趣的纳入和排除标准被排除,24项根据核心数据被纳入。结果:一篇综述作者确定了符合本综述纳入标准的随机试验。两位综述作者提取数据并评估研究质量。下颌全无牙患者佩戴种植支撑覆盖义齿的口腔健康相关生活质量优于常规组织支撑全口义齿,至少佩戴2个种植支撑下颌全口义齿即可充分改善口腔健康相关生活质量。结论:在过去的二十年里,大约有170多篇评论和临床试验发表了支持这一观点的文章。因此,临床医生可能不会尝试在成形良好的下颌无牙嵴上放置额外的种植体。为了提高对下颌种植覆盖义齿治疗的认识,临床医生必须仔细审查现有证据,并在有效治疗和循证治疗之间取得平衡,制定治疗方案。
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引用次数: 4
Knowledge, Attitudes, and Practices of Dental Patients Toward Cross-Infection and Economic Implications in View of Covid-19: An Online Survey 针对Covid-19的牙科患者对交叉感染的知识、态度和实践及其经济影响:一项在线调查
IF 0.7 Pub Date : 2020-11-29 DOI: 10.1177/2320206820972250
Rhythm Bains, A. Tikku, V. Bains, Promila Verma
Aim: To assess the knowledge, attitude, and practices of the patients regarding cross-infection in dental clinics in view of COVID-19, and its economic implications. Materials and Methods: The present study is a cross-sectional online survey done using Google Forms tool which was shared amongst 501 participants via e-mail and various social media platforms. It consisted of 42 structured questions regarding sociodemographics (seven questions), knowledge of COVID-19 (seven questions), practices regarding COVID-19 preventive methods (five questions), knowledge regarding cross-infection in dental clinics (nine questions), attitudes toward infection in dental clinics, and increased cost of treatment due to added disinfection protocols (14 questions). All the associations were tested using the chi-square test and with the P-value set at <.05. The significance level was taken as α = 0.05; therefore, a difference or association with P-value <.05 was considered statistically significant. The linear regression model was used to relate demographics with the knowledge attitude practices items, and Pearson’s correlation coefficient was used to evaluate the correlation between knowledge, attitudes, and practices. Results: A total of 478 responses were assessed. 92.2% of the respondents had high knowledge regarding COVID-19, and only 48.1% had a high knowledge score regarding infection control in dental clinics. The respondents exhibited high scores for practice related to COVID-19 (83.9%) and attitude toward infection control in dental clinics (91.9%). Using the Pearson’s correlation coefficient, knowledge attitude practices variables showed a significant correlation amongst each other (P < .001). Only 60% responded that extra infection control protocols will increase the treatment charges, and approximately 30% responded that they will not pay or were not sure of paying the extra charges. The proportion of respondents who were agreeing about paying the increase cost were independent of age (P = .226), gender (P = .328), education (P = .085), and profession (P = .121). Conclusion: A significant percentage of patients today have a lot of knowledge of COVID-19. Also, they have higher expectations than before from their dental health care providers regarding infection control.
目的:了解2019冠状病毒病(COVID-19)背景下牙科门诊患者对交叉感染的认知、态度和行为,并探讨其经济意义。材料和方法:本研究是一项横断面在线调查,使用谷歌表单工具,通过电子邮件和各种社交媒体平台在501名参与者中共享。调查包括42个结构化问题,涉及社会人口统计学(7个问题)、COVID-19知识(7个问题)、COVID-19预防方法实践(5个问题)、牙科诊所交叉感染知识(9个问题)、牙科诊所对感染的态度以及由于增加消毒方案而增加的治疗费用(14个问题)。所有关联均采用卡方检验,p值设置为< 0.05。显著性水平取α = 0.05;因此,与p值<的差异或关联。0.05认为有统计学意义。采用线性回归模型将人口统计学与知识态度实践项目联系起来,并采用Pearson相关系数评估知识、态度和实践之间的相关性。结果:共评估了478例应答。92.2%的受访者对新冠肺炎知识知晓率较高,仅48.1%的受访者对牙科诊所感染控制知识得分较高。受访者在与新冠肺炎相关的实践(83.9%)和对牙科诊所感染控制的态度(91.9%)方面得分较高。运用Pearson相关系数,知识态度实践变量之间呈现显著相关(P < 0.001)。只有60%的人回答说,额外的感染控制协议将增加治疗费用,大约30%的人回答说,他们不会支付或不确定支付额外的费用。同意支付增加费用的受访者比例与年龄(P = .226)、性别(P = .328)、教育程度(P = .085)和职业(P = .121)无关。结论:今天有相当比例的患者对COVID-19有很多了解。此外,他们对牙科保健提供者对感染控制的期望也比以前更高。
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引用次数: 7
A Radiographic Assessment of Dental Morbidity in Patients with Multiple Myeloma Undergoing Autologous Stem Cell Transplant: A Retrospective Study 自体干细胞移植后多发性骨髓瘤患者牙齿发病率的影像学评估:一项回顾性研究
IF 0.7 Pub Date : 2020-11-28 DOI: 10.1177/2320206820975981
Taggreed Wazzan, Rohan Jagtap, M. Mona, J. Katz
Aim: To assess the dental and oral morbidity in multiple myeloma patients as expressed in dental radiographs before autologous stem cell transplant. Materials and Methods: A retrospective study involving 79 multiple myeloma patients was designed to collect data prior to their autologous stem cell transplant. Patients were seen at the oral medicine clinic at the University of Florida College of Dentistry during the years 2010–2013. Through available patient data and interpretation of radiographs, the following variables were recorded: age, gender, carious lesions, periodontal disease, and periapical radiolucency. In addition, the incidence of root fragment retention and the presence of punched-out osteolytic lesions were recorded. Cochran–Mantel–Haenszel (CMH) tests and logistic regression were performed for descriptive analysis and presentation of the data. Results: Seventy-nine multiple myeloma patients were recruited for this study. Ages ranged from 28 to 79 years (mean = 61, SD = 9.6), including 41 (51.9%) females and 38 (48.1%) males. The results demonstrated dental decay in 64.56% of patients, periodontal disease in 62.03%, apical rarefying osteitis in 13.92% of patients, and punched-out lesions in 24.05% of patients. Conclusion: Our study indicates high dental morbidity in multiple myeloma patients prior to autologous stem cell transplant. The elimination of foci of infection is highly recommended prior to autologous stem cell transplant for this high-risk population because of the potential risk of bacteremia/septicemia from oral bacteria associated with dental morbidity.
目的:探讨自体干细胞移植前多发性骨髓瘤患者的口腔及口腔发病率。材料和方法:一项涉及79例多发性骨髓瘤患者的回顾性研究旨在收集其自体干细胞移植前的数据。患者于2010-2013年在佛罗里达大学牙科学院的口腔医学诊所就诊。通过现有的患者资料和对x线片的解读,记录了以下变量:年龄、性别、龋齿损害、牙周病和根尖周透光度。此外,还记录了根碎片保留的发生率和穿孔溶骨性病变的存在。采用Cochran-Mantel-Haenszel (CMH)检验和logistic回归对数据进行描述性分析和呈现。结果:79例多发性骨髓瘤患者被纳入本研究。年龄28 ~ 79岁,平均61岁,SD = 9.6,其中女性41例(51.9%),男性38例(48.1%)。结果显示:龋齿占64.56%,牙周病占62.03%,根尖分化性骨炎占13.92%,穿孔性病变占24.05%。结论:我们的研究表明自体干细胞移植前多发性骨髓瘤患者的牙齿发病率很高。强烈建议在自体干细胞移植之前消除感染灶,因为与牙齿发病率相关的口腔细菌有潜在的菌血症/败血症风险。
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引用次数: 0
Bonding Effectiveness of Contemporary Materials in Luting Glass-Ceramic to Dentine: An In Vitro Study 釉玻璃陶瓷与牙本质的结合效果:体外研究
IF 0.7 Pub Date : 2020-11-28 DOI: 10.1177/2320206820973496
A. Mutlu, A. Atay, E. Çal
Aim: To evaluate the shear bond strength (SBS) of resin cements, flowable composites, and a preheated composite in luting glass-ceramic to dentin. Materials and Methods: In total, 108 noncaries human third molar teeth embedded in acrylic blocks, grinded from the occlusal surfaces until dentin was exposed, and divided into 9 randomized groups (n = 12). In total, 108 ceramic samples prepared in disc shape (3mm × 3mm) from IPS e. max CAD (Ivoclar Vivadent) blocks. Four adhesive resin cements: Variolink Esthetic DC (Ivoclar Vivadent), G-CEM LinkForce (GC), Panavia V5 (Kuraray Noritake), Maxcem Elite Chroma (Kerr), and three flowable composites: G-ænial Universal Flo (GC), Herculite XRV Ultra Flow (Kerr), Vertise Flow (Kerr), and one preheated composite: Enamel Plus HRI (Micerium) luted to the prepared occlusal surfaces of the teeth with total-etch, self-etch, and self-adhesive protocols. Then samples were thermocyled (5,000 cycles, 5–55°C, dwell time 20 s). SBS test was performed in a universal testing machine (at 0.5 mm/min). Failure modes were examined under a stereomicroscope at ×25 magnification. Data were analyzed using Kruskal–Wallis and Dunn–Bonferroni tests (α = 0.05). Results: There were statistically significant differences among material types (P < .05). Highest SBS values found in G-ænial Universal Flo (15.43 ± 5.67), and the lowest values obtained in Maxcem Elite Choroma (SA) (1.25 ± 1.47). There were no significant differences between self-etch (Panavia V5, Maxcem Elite Choroma [SE]) and self-adhesive (Maxcem Elite Choroma [SA], Vertise Flow) protocols (P > .05). Conclusion: Flowable composites can be alternatives to resin cements when bonded with total-etch procedures. Bond strength of self-etch and self-adhesive applications is still to be developed.
目的:评价树脂胶合剂、可流动复合材料和预热复合材料在玻璃陶瓷与牙本质粘接中的剪切强度。材料与方法:将108颗非龋齿的人类第三磨牙嵌套在丙烯酸块中,从咬合表面磨牙直至露出牙本质,随机分为9组(n = 12)。总共108个陶瓷样品由IPS e.m ax CAD (Ivoclar Vivadent)块制成圆盘状(3mm × 3mm)。四种胶粘剂树脂水泥:Variolink thetic DC (Ivoclar Vivadent), G- cem LinkForce (GC), Panavia V5 (Kuraray Noritake), Maxcem Elite Chroma (Kerr),三种可流动复合材料:G- Universal Flo (GC), Herculite XRV Ultra Flow (Kerr), Vertise Flow (Kerr),以及一种加热复合材料:搪瓷+ HRI (Micerium),以全蚀刻,自蚀刻和自粘合的方式连接到牙齿的预备咬合表面。然后对样品进行热循环(5000次,5-55°C,停留时间20 s),在通用试验机(0.5 mm/min)中进行SBS测试。在×25放大的立体显微镜下检查失效模式。采用Kruskal-Wallis检验和Dunn-Bonferroni检验对数据进行分析(α = 0.05)。结果:材料类型间差异有统计学意义(P < 0.05)。G- nial Universal Flo的SBS值最高(15.43±5.67),Maxcem Elite Choroma (SA)的SBS值最低(1.25±1.47)。自蚀刻(Panavia V5, Maxcem Elite Choroma [SE])和自粘(Maxcem Elite Choroma [SA], Vertise Flow)方案之间无显著差异(P > 0.05)。结论:可流动复合材料可替代树脂胶结剂与全蚀刻工艺的结合。粘结强度的自蚀刻和自粘应用仍有待开发。
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引用次数: 5
Effect of Endodontic Treatment on Serum Glutathione (GSH) Levels in Patients with Chronic Apical Periodontitis: A Clinical Pilot Study 根管治疗对慢性根尖牙炎患者血清谷胱甘肽(GSH)水平的影响:一项临床初步研究
IF 0.7 Pub Date : 2020-11-25 DOI: 10.1177/2320206820958239
Rhythm Bains, A. Tikku, A. Chandra, W. Ali, Promila Verma
Aim: To assess the before- and after-treatment levels of glutathione (GSH) in the serum of patients with chronic apical periodontitis. Materials and Methods: The study involved 20 systemically healthy patients with radiographic evidence of chronic apical periodontitis in at least one tooth, of which 11 were finally assessed. 10 mL of the patient’s venous blood was obtained before commencing the endodontic treatment to assess the pre-operative serum GSH levels (T0). The canals cleaned and shaped, and irrigated with 2.5% sodium hypochlorite, and filled with a calcium hydroxide based intracanal medicament. At the subsequent appointment after one week, teeth were obturated. The patients were recalled 30 days after the completion of endodontic therapy, and blood samples were assessed again at time frame T1 for serum GSH. The difference in pre- and post-treatment values for T0 and T1 was statistically analyzed. Results: The mean age of the subjects (N = 11) was 21.09±3.24 years, with 19.50±0.71 years in female group and 21.44±3.50 years in the male group. The mean GSH at T0 was 11.73±8.30 units, which was increased to 14.04±13.96 units at T1. However, no significant change was observed in the GSH level from T0 to T1 (change = –2.30, t-value = –0.49, P = .635). Conclusion: The results of this study suggest that endodontic therapy may play a role in restoring the systemic oxidative balance, as seen by the increase in post-treatment serum GSH levels.
目的:探讨慢性根尖牙炎患者治疗前后血清谷胱甘肽(GSH)水平的变化。材料和方法:本研究纳入了20例全身健康且至少有一颗牙齿有慢性根尖牙周炎的患者,最终对其中11例进行了评估。开始根管治疗前取患者静脉血10ml,评估术前血清GSH水平(T0)。这些管道被清洁和塑形,用2.5%的次氯酸钠冲洗,并填充以氢氧化钙为基础的管内药物。在一周后的下一次预约中,牙齿被封闭。患者在完成根管治疗后30天被召回,并在时间框架T1再次评估血液样本的血清GSH。对T0和T1处理前后值的差异进行统计学分析。结果:11例患者平均年龄21.09±3.24岁,其中女性组19.50±0.71岁,男性组21.44±3.50岁。T0时平均GSH为11.73±8.30单位,T1时升高至14.04±13.96单位。然而,从T0到T1, GSH水平没有显著变化(变化= -2.30,t值= -0.49,P = .635)。结论:本研究结果表明,根管治疗可能在恢复全身氧化平衡中发挥作用,治疗后血清GSH水平升高。
{"title":"Effect of Endodontic Treatment on Serum Glutathione (GSH) Levels in Patients with Chronic Apical Periodontitis: A Clinical Pilot Study","authors":"Rhythm Bains, A. Tikku, A. Chandra, W. Ali, Promila Verma","doi":"10.1177/2320206820958239","DOIUrl":"https://doi.org/10.1177/2320206820958239","url":null,"abstract":"Aim: To assess the before- and after-treatment levels of glutathione (GSH) in the serum of patients with chronic apical periodontitis. Materials and Methods: The study involved 20 systemically healthy patients with radiographic evidence of chronic apical periodontitis in at least one tooth, of which 11 were finally assessed. 10 mL of the patient’s venous blood was obtained before commencing the endodontic treatment to assess the pre-operative serum GSH levels (T0). The canals cleaned and shaped, and irrigated with 2.5% sodium hypochlorite, and filled with a calcium hydroxide based intracanal medicament. At the subsequent appointment after one week, teeth were obturated. The patients were recalled 30 days after the completion of endodontic therapy, and blood samples were assessed again at time frame T1 for serum GSH. The difference in pre- and post-treatment values for T0 and T1 was statistically analyzed. Results: The mean age of the subjects (N = 11) was 21.09±3.24 years, with 19.50±0.71 years in female group and 21.44±3.50 years in the male group. The mean GSH at T0 was 11.73±8.30 units, which was increased to 14.04±13.96 units at T1. However, no significant change was observed in the GSH level from T0 to T1 (change = –2.30, t-value = –0.49, P = .635). Conclusion: The results of this study suggest that endodontic therapy may play a role in restoring the systemic oxidative balance, as seen by the increase in post-treatment serum GSH levels.","PeriodicalId":43017,"journal":{"name":"Journal of Advanced Oral Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2020-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84513439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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Journal of Advanced Oral Research
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