Pub Date : 2024-05-21DOI: 10.1177/23202068241242626
Gera Dinesh, K. Ramesh, Gautami S Penmetsa, P. Swetha, NVS Sruthima G, P. M. Kumar
Microbial colonization contributes to periodontitis and peri-implantitis with an increase in proinflammatory cytokines like IL 17. This has a vital role in the destructive process of tissue and bone around the implant. Type 2 diabetes mellitus has the potential to increase these microbial colonies thus becoming a risk factor. To compare and correlate the association of peri-implant sulcular microflora and salivary IL-17 between healthy and controlled diabetic individuals. A total of 30 participants who have undergone dental implant placement with screw-retained prosthesis were included in the study. Participants were divided into two groups, healthy ( n = 15) and diabetic ( n = 15). The subgingival plaque was collected from peri-implant sites into TE buffer vials and the salivary sample was collected into Eppendorf tubes at the 7th, 14th, and 30th day. Microbiological counts of P. gingivalis, T. denticola, T .forsythia, and F. nucleatum were evaluated by polymerase chain reaction, and salivary interleukin (IL)-17 levels were obtained by enzyme-linked immunosorbent assay. The bacterial count was increased in both healthy and diabetic individuals but more prevalent in diabetes. The salivary IL-17 levels were increased in diabetic individuals which was statistically significant. Increased microbiota in both healthy and diabetic individuals along with increased IL-17 levels can lead to peri-implantitis which provides an insight into microbiological and immunological aspects in individuals with dental implants further acting as a predictor for peri-implantitis.
{"title":"Microbiological and Immunological Assessment of Peri-implant Sites in Healthy and Diabetic Individuals After Prosthetic Rehabilitation: A Prospective Case Control Study","authors":"Gera Dinesh, K. Ramesh, Gautami S Penmetsa, P. Swetha, NVS Sruthima G, P. M. Kumar","doi":"10.1177/23202068241242626","DOIUrl":"https://doi.org/10.1177/23202068241242626","url":null,"abstract":"Microbial colonization contributes to periodontitis and peri-implantitis with an increase in proinflammatory cytokines like IL 17. This has a vital role in the destructive process of tissue and bone around the implant. Type 2 diabetes mellitus has the potential to increase these microbial colonies thus becoming a risk factor. To compare and correlate the association of peri-implant sulcular microflora and salivary IL-17 between healthy and controlled diabetic individuals. A total of 30 participants who have undergone dental implant placement with screw-retained prosthesis were included in the study. Participants were divided into two groups, healthy ( n = 15) and diabetic ( n = 15). The subgingival plaque was collected from peri-implant sites into TE buffer vials and the salivary sample was collected into Eppendorf tubes at the 7th, 14th, and 30th day. Microbiological counts of P. gingivalis, T. denticola, T .forsythia, and F. nucleatum were evaluated by polymerase chain reaction, and salivary interleukin (IL)-17 levels were obtained by enzyme-linked immunosorbent assay. The bacterial count was increased in both healthy and diabetic individuals but more prevalent in diabetes. The salivary IL-17 levels were increased in diabetic individuals which was statistically significant. Increased microbiota in both healthy and diabetic individuals along with increased IL-17 levels can lead to peri-implantitis which provides an insight into microbiological and immunological aspects in individuals with dental implants further acting as a predictor for peri-implantitis.","PeriodicalId":43017,"journal":{"name":"Journal of Advanced Oral Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141114154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-11DOI: 10.1177/23202068241238822
Emel Arslan, Kübra Deg˘irmenci
This study evaluates the effect of different surface finishing procedures on the color and translucency values of monolithic zirconia materials on three different colored composite backgrounds. Sixty monolithic zirconia blocks of three different translucency levels were prepared in vitro using computer-aided design/computer-aided manufacturing (CAD/CAM) systems. The correlation between repeat measurements was 0.5, resulting in a sample size of nine samples per group to detect a medium effect size, f = 0.25. Half of the zirconia blocks in each group were subjected to glazing, while the other half were polished ( n = 10). Composite blocks of three different colors were prepared to simulate dental substrates, and the zirconia specimens were placed on these composite backgrounds. The color parameters of the specimens were measured using a spectrophotometer on gray, black, and white backgrounds. Three-way repeated measure ANOVA was used to assess the interaction between the three independent variables (zirconia brand, surface finishing technique, and background color) and the effects of each tested variable on the changes in color and translucency. The surface finishing techniques had a significant effect on the color and translucency of the monolithic zirconia materials. Glazing resulted in higher color differences and lower translucency values compared to polishing. For backgrounds of the same color, no significant differences were detected between the glazed zirconia groups for the same condition ( p > .016). Overall, the study demonstrated the importance of selecting the appropriate surface finishing technique and translucency property of the monolithic zirconia materials to obtain the optimal esthetic results in dental restorations.
{"title":"Translucency and Color Difference of Monolithic Zirconia Restorations: The Effect of Surface Finishing on Background Color","authors":"Emel Arslan, Kübra Deg˘irmenci","doi":"10.1177/23202068241238822","DOIUrl":"https://doi.org/10.1177/23202068241238822","url":null,"abstract":"This study evaluates the effect of different surface finishing procedures on the color and translucency values of monolithic zirconia materials on three different colored composite backgrounds. Sixty monolithic zirconia blocks of three different translucency levels were prepared in vitro using computer-aided design/computer-aided manufacturing (CAD/CAM) systems. The correlation between repeat measurements was 0.5, resulting in a sample size of nine samples per group to detect a medium effect size, f = 0.25. Half of the zirconia blocks in each group were subjected to glazing, while the other half were polished ( n = 10). Composite blocks of three different colors were prepared to simulate dental substrates, and the zirconia specimens were placed on these composite backgrounds. The color parameters of the specimens were measured using a spectrophotometer on gray, black, and white backgrounds. Three-way repeated measure ANOVA was used to assess the interaction between the three independent variables (zirconia brand, surface finishing technique, and background color) and the effects of each tested variable on the changes in color and translucency. The surface finishing techniques had a significant effect on the color and translucency of the monolithic zirconia materials. Glazing resulted in higher color differences and lower translucency values compared to polishing. For backgrounds of the same color, no significant differences were detected between the glazed zirconia groups for the same condition ( p > .016). Overall, the study demonstrated the importance of selecting the appropriate surface finishing technique and translucency property of the monolithic zirconia materials to obtain the optimal esthetic results in dental restorations.","PeriodicalId":43017,"journal":{"name":"Journal of Advanced Oral Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140716611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-25DOI: 10.1177/23202068241237336
Nuran Çevik, E. Bodrumlu
The purpose of this study is to determine how fluoride varnish materials applied to polyacid modified composite resins (PMCR) affect roughness at various temperatures. In total, 100 PMCR discs were manufactured for this in vitro study, and the hundred samples were randomly split into five groups of twenty samples each. The samples in four groups had their surfaces coated with fluoride varnish at varying temperatures (4ºC, 23ºC, 39ºC, and 55ºC), while the samples in the control group did not get this treatment. A heating device is used for fluoride varnish. A profilometer was used to measure the samples’ surface roughness values after application. The Kruskal–Wallis and Shapiro–Wilk tests were used for statistical analysis. After comparing five groups with twenty samples apiece, it was found that 23ºC had the greatest average roughness value. For the fluoride varnish material cooked at various temperatures, there was no discernible statistical variation in the roughness values. The study’s results indicate that all groups’ surface roughness values following the application of fluoride varnish at varying temperatures were found to be clinically acceptable.
{"title":"Effects of Fluoride Varnish on Roughness of Polyacid-Modified Composite Resins at Different Temperatures: An In Vitro Study","authors":"Nuran Çevik, E. Bodrumlu","doi":"10.1177/23202068241237336","DOIUrl":"https://doi.org/10.1177/23202068241237336","url":null,"abstract":"The purpose of this study is to determine how fluoride varnish materials applied to polyacid modified composite resins (PMCR) affect roughness at various temperatures. In total, 100 PMCR discs were manufactured for this in vitro study, and the hundred samples were randomly split into five groups of twenty samples each. The samples in four groups had their surfaces coated with fluoride varnish at varying temperatures (4ºC, 23ºC, 39ºC, and 55ºC), while the samples in the control group did not get this treatment. A heating device is used for fluoride varnish. A profilometer was used to measure the samples’ surface roughness values after application. The Kruskal–Wallis and Shapiro–Wilk tests were used for statistical analysis. After comparing five groups with twenty samples apiece, it was found that 23ºC had the greatest average roughness value. For the fluoride varnish material cooked at various temperatures, there was no discernible statistical variation in the roughness values. The study’s results indicate that all groups’ surface roughness values following the application of fluoride varnish at varying temperatures were found to be clinically acceptable.","PeriodicalId":43017,"journal":{"name":"Journal of Advanced Oral Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140384479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-25DOI: 10.1177/23202068241239150
Shereen Farhana P, Arul Prakash Francis, Gayathri R., K. Sankaran, V. Veeraraghavan
Zirconium oxide nanoparticles have unique properties that could be useful in various applications, including implants, biosensors, anticancer, and antimicrobial agents. To enhance their suitability as coatings for prosthetic implants, quercetin, a flavanol abundant in plants, serves as an effective functionalization agent, enhancing nanoparticle solubility, stability, and bioavailability. This study focuses on synthesizing zirconium oxide nanoparticles using Hemidesmus indicus (H. indicus) root extract and functionalizing them with quercetin. Further, their biocompatibility, antioxidant and antimicrobial activity are evaluated to target their application as coatings for prosthetic implants. Zirconium oxide nanoparticles were prepared using H. indicus root extract (H-ZrO2NPs) and decorated with quercetin followed by pegylation. The nanoparticles were characterized using various characterization techniques including UV–vis spectroscopy (UV–Vis), Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy, and energy-dispersive X-ray analysis. The biological activity of the nanoparticles was evaluated using biocompatibility, antioxidant, and antibacterial assays. Biocompatibility was tested by investigating the interaction between the quercetin-functionalized zirconium oxide nanoparticles (HQZN) and erythrocytes. The antibacterial and antioxidant efficacy of H-ZrO2NPs and HQZN was tested and compared with the standard drug. The results were statistically analyzed using one-way ANOVA followed by Dunnett’s multiple comparison tests. H-ZrO2NPs were successfully synthesized using H. root extract and functionalized with quercetin. The characterization of nanoparticles using various techniques confirmed their morphology, elemental composition, functionalization, crystallinity, size, and stability. The nanoparticles were appearing spherical in shape with a size range of 20–120 nm. The crystallinity of H-ZrO2NPs is found to be enhanced with quercetin functionalization. In vitro, bioactivity studies revealed the antioxidant and antibacterial efficacy of HQZN. The hemocompatibility of HQZN was proved by investigating its interaction with erythrocytes. The study findings revealed that the biocompatible HQZN holds notable antioxidant and antibacterial properties. On the other hand, further comprehensive investigation using an in vivo model is vital to appreciate their efficacy and toxicity profile.
{"title":"Synthesis and Characterization of Zirconium Oxide Nanoparticles Based on Hemidesmus Indicus Extract: Evaluation of Biocompatibility and Bioactivity for Prosthetic Implant Coatings","authors":"Shereen Farhana P, Arul Prakash Francis, Gayathri R., K. Sankaran, V. Veeraraghavan","doi":"10.1177/23202068241239150","DOIUrl":"https://doi.org/10.1177/23202068241239150","url":null,"abstract":"Zirconium oxide nanoparticles have unique properties that could be useful in various applications, including implants, biosensors, anticancer, and antimicrobial agents. To enhance their suitability as coatings for prosthetic implants, quercetin, a flavanol abundant in plants, serves as an effective functionalization agent, enhancing nanoparticle solubility, stability, and bioavailability. This study focuses on synthesizing zirconium oxide nanoparticles using Hemidesmus indicus (H. indicus) root extract and functionalizing them with quercetin. Further, their biocompatibility, antioxidant and antimicrobial activity are evaluated to target their application as coatings for prosthetic implants. Zirconium oxide nanoparticles were prepared using H. indicus root extract (H-ZrO2NPs) and decorated with quercetin followed by pegylation. The nanoparticles were characterized using various characterization techniques including UV–vis spectroscopy (UV–Vis), Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy, and energy-dispersive X-ray analysis. The biological activity of the nanoparticles was evaluated using biocompatibility, antioxidant, and antibacterial assays. Biocompatibility was tested by investigating the interaction between the quercetin-functionalized zirconium oxide nanoparticles (HQZN) and erythrocytes. The antibacterial and antioxidant efficacy of H-ZrO2NPs and HQZN was tested and compared with the standard drug. The results were statistically analyzed using one-way ANOVA followed by Dunnett’s multiple comparison tests. H-ZrO2NPs were successfully synthesized using H. root extract and functionalized with quercetin. The characterization of nanoparticles using various techniques confirmed their morphology, elemental composition, functionalization, crystallinity, size, and stability. The nanoparticles were appearing spherical in shape with a size range of 20–120 nm. The crystallinity of H-ZrO2NPs is found to be enhanced with quercetin functionalization. In vitro, bioactivity studies revealed the antioxidant and antibacterial efficacy of HQZN. The hemocompatibility of HQZN was proved by investigating its interaction with erythrocytes. The study findings revealed that the biocompatible HQZN holds notable antioxidant and antibacterial properties. On the other hand, further comprehensive investigation using an in vivo model is vital to appreciate their efficacy and toxicity profile.","PeriodicalId":43017,"journal":{"name":"Journal of Advanced Oral Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140384483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-21DOI: 10.1177/23202068241237329
Deebah Choudhary, Ana Gupta, Nidhi Bharti
This study aimed to evaluate the penetration depth and persistence of sealer residues in obturated canals with three different bioceramic sealers using confocal microscopy. In total, 60 single-rooted human premolars were selected and decoronated to maintain the working length of 14 mm. The samples were biomechanically prepared and obturated with Protaper Universal GP coated with three different bioceramic sealers, that is, CeraSeal RC, Bio-C and MTA Fillapex. The specimens were divided into three groups ( n = 20) depending on the sealer used. Rhodamine B fluorescent dye was added to the sealers before using them for obturation. The obturated samples were sealed and placed in 100% humidity at 37oC for 7 days. Gutta-percha was removed from all the samples using retreatment files. Each sample was horizontally sectioned into 2 mm thick slices at 3 mm and 5 mm from the apex, which were analysed under a confocal scanning microscope to detect the depth of penetration of sealer into the dentinal tubules. Data were analysed using one-way ANOVA and Tukey’s post hoc tests. Intergroup comparison of penetration depth at 3 mm showed that the mean depth of penetration among CeraSeal samples was found to be significantly more as compared to the other two materials, while, no statistically significant difference was found among Bio-C and MTA Fillapex with the significance level established at 5% ( P < .05). Similarly, an intergroup comparison of penetration depth at 5 mm showed that the mean depth of penetration among CeraSeal samples was found to be significantly more as compared to the other two materials, while, no statistically significant difference was found among Bio-C and MTA Fillapex. CeraSeal RC sealer showed significantly higher depth of penetration than Bio-C and MTA Fillapex. All bioceramic sealers show a significant penetration into the dentinal tubules. However, none of the sealers was completely removed from the tubules following retreatment.
本研究旨在使用共聚焦显微镜评估三种不同生物陶瓷封闭剂在封闭后的残留物的渗透深度和持久性。研究共选择了 60 颗单根人类前臼齿，并对其进行了装饰，以保持 14 毫米的工作长度。对样本进行生物力学制备，并用涂有三种不同生物陶瓷封闭剂（即 CeraSeal RC、Bio-C 和 MTA Fillapex）的 Protaper Universal GP 进行封闭。根据所用封闭剂的不同，试样被分为三组（n = 20）。在使用封闭剂进行封闭前，在封闭剂中添加罗丹明 B 荧光染料。封固后的样本被密封，并放置在 37oC 100%湿度的环境中 7 天。使用再处理锉去除所有样本上的水凝胶。在共聚焦扫描显微镜下进行分析，以检测封闭剂渗入牙本质小管的深度。数据分析采用单因素方差分析和 Tukey 后检验。3 毫米渗透深度的组间比较显示，CeraSeal 样品的平均渗透深度明显高于其他两种材料，而 Bio-C 和 MTA Fillapex 之间则没有显著差异，显著性水平为 5%（P < .05）。同样，5 毫米渗透深度的组间比较显示，CeraSeal 样品的平均渗透深度明显高于其他两种材料，而 Bio-C 和 MTA Fillapex 之间则没有统计学意义上的显著差异。CeraSeal RC 封闭剂的渗透深度明显高于 Bio-C 和 MTA Fillapex。所有生物陶瓷封闭剂都能明显渗入牙本质小管。不过，在再治疗后，没有一种封闭剂能完全从牙本质小管中清除。
{"title":"Comparative Evaluation of Penetrability of Various Bioceramic Sealers into the Tubules of Radicular Dentin","authors":"Deebah Choudhary, Ana Gupta, Nidhi Bharti","doi":"10.1177/23202068241237329","DOIUrl":"https://doi.org/10.1177/23202068241237329","url":null,"abstract":"This study aimed to evaluate the penetration depth and persistence of sealer residues in obturated canals with three different bioceramic sealers using confocal microscopy. In total, 60 single-rooted human premolars were selected and decoronated to maintain the working length of 14 mm. The samples were biomechanically prepared and obturated with Protaper Universal GP coated with three different bioceramic sealers, that is, CeraSeal RC, Bio-C and MTA Fillapex. The specimens were divided into three groups ( n = 20) depending on the sealer used. Rhodamine B fluorescent dye was added to the sealers before using them for obturation. The obturated samples were sealed and placed in 100% humidity at 37oC for 7 days. Gutta-percha was removed from all the samples using retreatment files. Each sample was horizontally sectioned into 2 mm thick slices at 3 mm and 5 mm from the apex, which were analysed under a confocal scanning microscope to detect the depth of penetration of sealer into the dentinal tubules. Data were analysed using one-way ANOVA and Tukey’s post hoc tests. Intergroup comparison of penetration depth at 3 mm showed that the mean depth of penetration among CeraSeal samples was found to be significantly more as compared to the other two materials, while, no statistically significant difference was found among Bio-C and MTA Fillapex with the significance level established at 5% ( P < .05). Similarly, an intergroup comparison of penetration depth at 5 mm showed that the mean depth of penetration among CeraSeal samples was found to be significantly more as compared to the other two materials, while, no statistically significant difference was found among Bio-C and MTA Fillapex. CeraSeal RC sealer showed significantly higher depth of penetration than Bio-C and MTA Fillapex. All bioceramic sealers show a significant penetration into the dentinal tubules. However, none of the sealers was completely removed from the tubules following retreatment.","PeriodicalId":43017,"journal":{"name":"Journal of Advanced Oral Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140221217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-14DOI: 10.1177/23202068241235748
A. Ozdogan, Gizem Erdas, Ozge Gulmez, Furkan Karatas
This study aims to assess how well light-cured resin cements and the corresponding try-in pastes match in terms of color. A1 color blocks containing three different types of ceramic materials were used to generate 120 specimens (5 × 5 mm2). These specimens were split into two thickness-based groups, and the groups were then randomly allocated to receive various kinds of resin cement. Composite substrate blocks with A3 color and dimensions of 4 mm thickness were used to simulate dentin substrates. Color measurements were taken before and after the application of try-in pastes and resin cements using a spectrophotometer. The obtained results were analyzed using the CIELab and CIEDE2000 frameworks, and statistical analysis was performed using a three-way ANOVA test and paired sample t-test with a significance level of α = 0.05. There were no significant interactions between material, thickness, and cement in relation to color in both evaluation systems ( p > .05). However, there were significant differences in the a* values (green-red axis) between the try-in pastes and resin cements ( p < .05), while no significant differences were observed in the L* (lightness) and b* (blue-yellow axis) values ( p > .05). The try-in pastes utilized for pre-cementation evaluation exhibited favorable color compatibility with the corresponding resin cements.
{"title":"Color Matching between Resin Cements and Try-in Pastes in Glass Ceramics at Different Thicknesses","authors":"A. Ozdogan, Gizem Erdas, Ozge Gulmez, Furkan Karatas","doi":"10.1177/23202068241235748","DOIUrl":"https://doi.org/10.1177/23202068241235748","url":null,"abstract":"This study aims to assess how well light-cured resin cements and the corresponding try-in pastes match in terms of color. A1 color blocks containing three different types of ceramic materials were used to generate 120 specimens (5 × 5 mm2). These specimens were split into two thickness-based groups, and the groups were then randomly allocated to receive various kinds of resin cement. Composite substrate blocks with A3 color and dimensions of 4 mm thickness were used to simulate dentin substrates. Color measurements were taken before and after the application of try-in pastes and resin cements using a spectrophotometer. The obtained results were analyzed using the CIELab and CIEDE2000 frameworks, and statistical analysis was performed using a three-way ANOVA test and paired sample t-test with a significance level of α = 0.05. There were no significant interactions between material, thickness, and cement in relation to color in both evaluation systems ( p > .05). However, there were significant differences in the a* values (green-red axis) between the try-in pastes and resin cements ( p < .05), while no significant differences were observed in the L* (lightness) and b* (blue-yellow axis) values ( p > .05). The try-in pastes utilized for pre-cementation evaluation exhibited favorable color compatibility with the corresponding resin cements.","PeriodicalId":43017,"journal":{"name":"Journal of Advanced Oral Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140242569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-19DOI: 10.1177/23202068231220446
S. K. Kumar, Mohit Kumar, Nikita Sharma, Pulkit Arora, Megna Bhatt, Sravyanjali Akkanapally
An assessment and comparison of three retreatment files was conducted to determine their effectiveness in the retrieval of gutta-percha. In the investigation, 60 extracted single-rooted human teeth having straight canals and complete apices were used. The ProTaper Universal file system was used to prepare teeth and obturated using gutta-percha with sealant AH Plus utilizing down pack and backfill obturation technique. Removal was performed with ProTaper, D-RaCe files, MTwo, and R-Endo retreatment files. Using a stopwatch, the time needed to take out the GP was also calculated in seconds. We used ANOVA along with the post hoc Tukey’s test to analyze the quantity of obturating material in apical, middle, and coronal third following decoronation and longitudinal splitting. The average percentage of gutta-percha points removed across root levels varied significantly among the ProTaper, D-RaCe MTwo, and R-Endo groups. With the exception of the ProTaper group, when the middle level displayed the most removal, the coronal level showed much higher removal than the mid-root level, while the apical level often exhibited the highest removal. ProTaper retreatment files outperformed MTwo, D-RaCe, and R-Endo among the four groups in terms of removing root canal filling material. However, none of the experimental groups removed gutta-percha completely from root canals.
{"title":"Comparative Evaluation of the Efficacy of Different Ni-Ti Rotary Instruments in Removal of Gutta-Percha During Root Canal Retreatment: An in vitro Study","authors":"S. K. Kumar, Mohit Kumar, Nikita Sharma, Pulkit Arora, Megna Bhatt, Sravyanjali Akkanapally","doi":"10.1177/23202068231220446","DOIUrl":"https://doi.org/10.1177/23202068231220446","url":null,"abstract":"An assessment and comparison of three retreatment files was conducted to determine their effectiveness in the retrieval of gutta-percha. In the investigation, 60 extracted single-rooted human teeth having straight canals and complete apices were used. The ProTaper Universal file system was used to prepare teeth and obturated using gutta-percha with sealant AH Plus utilizing down pack and backfill obturation technique. Removal was performed with ProTaper, D-RaCe files, MTwo, and R-Endo retreatment files. Using a stopwatch, the time needed to take out the GP was also calculated in seconds. We used ANOVA along with the post hoc Tukey’s test to analyze the quantity of obturating material in apical, middle, and coronal third following decoronation and longitudinal splitting. The average percentage of gutta-percha points removed across root levels varied significantly among the ProTaper, D-RaCe MTwo, and R-Endo groups. With the exception of the ProTaper group, when the middle level displayed the most removal, the coronal level showed much higher removal than the mid-root level, while the apical level often exhibited the highest removal. ProTaper retreatment files outperformed MTwo, D-RaCe, and R-Endo among the four groups in terms of removing root canal filling material. However, none of the experimental groups removed gutta-percha completely from root canals.","PeriodicalId":43017,"journal":{"name":"Journal of Advanced Oral Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139959248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-19DOI: 10.1177/23202068241228722
M. Shaikh, Nikolaos Christidis, Muhammad Sohail Zafar, D. Michelogiannakis, P. E. Rossouw, K. I. Afrashtehfar, Fawad Javed
The authors of the present study speculate that metastasis of breast cancer cells to the temporomandibular joint (TMJ) region mimics classical signs and symptoms of temporomandibular disorders (TMD). The aim of this mapping review was to investigate the association between metastatic breast cancer (MBC) and TMD. The focused question was, “Is there an association between MBC and TMD?” Indexed databases (PubMed/Medline, EMBASE, OVID, Scopus, Google Scholar, and Web of Science) were electronically searched up to and including March 2022. These databases were searched using different combinations of the following keywords: cancer, carcinoma, temporomandibular disorders, temporomandibular joint, disc displacement disorder, nociception, and tumor. Original clinical studies that meet the inclusion criteria were included. The risk of bias (RoB) was assessed using the Joanna Briggs Institute Critical Appraisal Checklist for case reports. The structure of this current evidence-based review was tailored to primarily condense the relevant information. Fifteen case reports were selected after screening the retrieved records from the electronic search. Fifteen out of 16 patients were women aged between 32 and 78 years. All patients were diagnosed with MBC, and most presented with adenocarcinoma. The symptoms identified in patients with TMD included: (a) preauricular pain; (b) preauricular swelling; (c) limited mouth opening; and (d) malocclusion. Fourteen of the included studies had a low RoB, while one had a moderate RoB. Based on the currently available evidence, a direct association between TMD and MBC or vice versa cannot be established. Routine visits to medical and oro-dental healthcare providers can contribute toward early diagnosis and management of TMD and MBC.
本研究的作者推测，乳腺癌细胞转移到颞下颌关节 (TMJ) 区域会模仿颞下颌关节紊乱 (TMD) 的典型体征和症状。本图谱综述旨在研究转移性乳腺癌 (MBC) 与 TMD 之间的关联。重点问题是："MBC 与 TMD 之间是否存在关联？对截至 2022 年 3 月（含 2022 年 3 月）的索引数据库（PubMed/Medline、EMBASE、OVID、Scopus、Google Scholar 和 Web of Science）进行了电子检索。使用以下关键词的不同组合对这些数据库进行了检索：癌症、癌、颞下颌关节紊乱、颞下颌关节、椎间盘移位症、痛觉和肿瘤。符合纳入标准的原创临床研究均被纳入其中。偏倚风险（RoB）采用乔安娜-布里格斯研究所（Joanna Briggs Institute）病例报告批判性评估清单进行评估。本篇循证综述的结构主要是为了浓缩相关信息。在对电子搜索检索到的记录进行筛选后，选出了 15 篇病例报告。16 位患者中有 15 位是女性，年龄在 32 岁至 78 岁之间。所有患者均被确诊为多发性乳腺癌，其中大多数患者表现为腺癌。TMD 患者的症状包括(a) 耳前疼痛；(b) 耳前肿胀；(c) 张口受限；以及 (d) 咬合不良。其中 14 项研究的 RoB 值较低，1 项研究的 RoB 值中等。根据现有证据，无法确定 TMD 与 MBC 之间存在直接联系，反之亦然。对医疗和口腔保健提供者进行常规就诊有助于对 TMD 和 MBC 进行早期诊断和管理。
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Pub Date : 2024-02-19DOI: 10.1177/23202068241229302
Antonio Hernández-Morales, B. S. González-López, R. Scougall-Vilchis, U. Velázquez-Enriquez, Mario I. Ortiz, M. Veras-Hernández, J. F. Casanova-Rosado, A. J. Casanova-Rosado, Carlo Eduardo Medina-Solís, G. Maupomé
The aim of this study was to quantify the association between the incidence and mortality of salivary gland cancer (SGC) with the consumption of tobacco and with the Human Development Index (HDI). An ecological study was designed using SGC incidence and mortality data in 172 countries in 2020, reported per 100,000 population with an age range of 10–85 years. Such dependent variables were obtained from the Global Cancer Observatory (GLOBOCAN). The prevalences of smoked and chewed tobacco were obtained from reports made in 2019, sourced from Global Burden of Diseases Study, while the HDI was obtained from the Human Development Report (2019) presented by the United Nations Development Program, and were considered independent variables. Statistical analysis was performed in Stata using Spearman’s correlation test. In 2020, there were 53,583 new cases of SGC worldwide, and countries with very high HDI exhibited a higher incidence. In terms of mortality, there were 22,778 cases worldwide, and countries with a moderate HDI showed a higher number of deaths. SGC mortality was associated with chewing tobacco use overall and in women. Surprising negative associations were found with the incidence of SGC and tobacco smoking in men, as well as with mortality of SGC and smoking overall and in women. CGS mortality was negatively associated with the HDI and all its components. In this international overview, SGC mortality is associated with chewing tobacco in women, as well as with the HDI and its components.
{"title":"Incidence and Mortality of Salivary Gland Cancer Worldwide and Its Correlation with Tobacco Use (Smoking and Chewing) and With the Human Development Index","authors":"Antonio Hernández-Morales, B. S. González-López, R. Scougall-Vilchis, U. Velázquez-Enriquez, Mario I. Ortiz, M. Veras-Hernández, J. F. Casanova-Rosado, A. J. Casanova-Rosado, Carlo Eduardo Medina-Solís, G. Maupomé","doi":"10.1177/23202068241229302","DOIUrl":"https://doi.org/10.1177/23202068241229302","url":null,"abstract":"The aim of this study was to quantify the association between the incidence and mortality of salivary gland cancer (SGC) with the consumption of tobacco and with the Human Development Index (HDI). An ecological study was designed using SGC incidence and mortality data in 172 countries in 2020, reported per 100,000 population with an age range of 10–85 years. Such dependent variables were obtained from the Global Cancer Observatory (GLOBOCAN). The prevalences of smoked and chewed tobacco were obtained from reports made in 2019, sourced from Global Burden of Diseases Study, while the HDI was obtained from the Human Development Report (2019) presented by the United Nations Development Program, and were considered independent variables. Statistical analysis was performed in Stata using Spearman’s correlation test. In 2020, there were 53,583 new cases of SGC worldwide, and countries with very high HDI exhibited a higher incidence. In terms of mortality, there were 22,778 cases worldwide, and countries with a moderate HDI showed a higher number of deaths. SGC mortality was associated with chewing tobacco use overall and in women. Surprising negative associations were found with the incidence of SGC and tobacco smoking in men, as well as with mortality of SGC and smoking overall and in women. CGS mortality was negatively associated with the HDI and all its components. In this international overview, SGC mortality is associated with chewing tobacco in women, as well as with the HDI and its components.","PeriodicalId":43017,"journal":{"name":"Journal of Advanced Oral Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140451418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-20DOI: 10.1177/23202068231210739
Meena Singh, A. Tikku, Promila Verma, Rakesh K. Yadav, Ramesh Bharti, Rhythm Bains
The purpose of the current investigation was to determine by radiographic means if a calcific dentinal bridge had formed following direct pulp capping (DPC) with calcium hydroxide (CH), mineral trioxide aggregate (MTA), or a combination of platelet-rich fibrin (PRF) and MTA. In the beginning, 45 systemically healthy patients who needed DPC and had pulpal exposure were enrolled in the trial. They were then randomly assigned to one of three groups: CH (control, n = 15), MTA ( n = 15), or PRF + MTA ( n = 15). To determine the radiographic density of the dentin immediately underneath the location of pulpal exposure, pre-operative intraoral digital radiographs of the afflicted teeth were acquired. Through sequential imaging, the radiographic evaluation of dentinal bridge formation was performed. All images were studied carefully, keeping the reference point constant. Out of the 45 patients, finally 10 per group were analysed. According to an analysis of variance, difference in mean density values among the various groups was found to be significant [( p = .001). On bi-group comparison (using post-Tukey HSD), difference between CH and PRF + MTA was significant ( p = .001), between MTA and PRF + MTA was significant ( p = .022), and between CH and MTA not significant ( p = .347)]. The PRF + MTA group showed the highest increase in mean density values. The results of the present study suggest that PRF and MTA when used in combination have better radiographic outcomes compared to MTA alone when used as DPC agents.
{"title":"Radiographic Outcomes of Mineral Trioxide Aggregate (MTA) with and Without Platelet-Rich Fibrin (PRF) In Direct Pulp Capping: A Clinical Pilot Study","authors":"Meena Singh, A. Tikku, Promila Verma, Rakesh K. Yadav, Ramesh Bharti, Rhythm Bains","doi":"10.1177/23202068231210739","DOIUrl":"https://doi.org/10.1177/23202068231210739","url":null,"abstract":"The purpose of the current investigation was to determine by radiographic means if a calcific dentinal bridge had formed following direct pulp capping (DPC) with calcium hydroxide (CH), mineral trioxide aggregate (MTA), or a combination of platelet-rich fibrin (PRF) and MTA. In the beginning, 45 systemically healthy patients who needed DPC and had pulpal exposure were enrolled in the trial. They were then randomly assigned to one of three groups: CH (control, n = 15), MTA ( n = 15), or PRF + MTA ( n = 15). To determine the radiographic density of the dentin immediately underneath the location of pulpal exposure, pre-operative intraoral digital radiographs of the afflicted teeth were acquired. Through sequential imaging, the radiographic evaluation of dentinal bridge formation was performed. All images were studied carefully, keeping the reference point constant. Out of the 45 patients, finally 10 per group were analysed. According to an analysis of variance, difference in mean density values among the various groups was found to be significant [( p = .001). On bi-group comparison (using post-Tukey HSD), difference between CH and PRF + MTA was significant ( p = .001), between MTA and PRF + MTA was significant ( p = .022), and between CH and MTA not significant ( p = .347)]. The PRF + MTA group showed the highest increase in mean density values. The results of the present study suggest that PRF and MTA when used in combination have better radiographic outcomes compared to MTA alone when used as DPC agents.","PeriodicalId":43017,"journal":{"name":"Journal of Advanced Oral Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139168570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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