首页 > 最新文献

Journal of Breast Imaging最新文献

英文 中文
Recent Trends in Breast Cancer Mortality Rates for U.S. Women by Age and Race/Ethnicity.
IF 2 Q3 ONCOLOGY Pub Date : 2025-03-06 DOI: 10.1093/jbi/wbaf007
Debra L Monticciolo, R Edward Hendrick

Objective: To analyze recent trends in U.S. breast cancer mortality rates by age group and race and ethnicity.

Methods: This retrospective analysis of female breast cancer mortality rates used National Center for Health Statistics data from 1990 to 2022 for all women, by age group, and by race or ethnicity. Joinpoint analysis assessed trends in breast cancer mortality rates.

Results: Breast cancer mortality rates for women 20 to 39 years old decreased 2.8% per year from 1999 to 2010 but showed no decline from 2010 to 2022 (annual percentage change [APC], -0.01; P = .98). For women of ages 40 to 74 years, breast cancer mortality rates decreased 1.7% to 3.9% per year from 1990 to 2022 (P <.001); a decline was found for all cohorts in this age group except Asian women. For women ≥75 years of age, breast cancer mortality rates declined significantly from 1993 to 2013 (APC, -1.26; P = .01) but showed no evidence of decline from 2013 to 2022 (APC, -0.2; P = .24). Across all ages, breast cancer mortality rates declined for White and Black women but not for Asian, Hispanic, and Native American women. Asian women ≥75 years of age had significantly increasing mortality rates (APC, 0.73; P <.001). For 2004 to 2022, breast cancer mortality rates were 39% higher in Black women than White women and varied strongly by age group: 104% for ages 20 to 39 years, 51% for ages 40 to 74 years, and 13% for ages ≥75 years.

Conclusion: Female breast cancer mortality rates have stopped declining in women <40 years of age and >74 years of age. The higher mortality rates in Black women compared with White women are age dependent and substantially higher in younger women.

{"title":"Recent Trends in Breast Cancer Mortality Rates for U.S. Women by Age and Race/Ethnicity.","authors":"Debra L Monticciolo, R Edward Hendrick","doi":"10.1093/jbi/wbaf007","DOIUrl":"https://doi.org/10.1093/jbi/wbaf007","url":null,"abstract":"<p><strong>Objective: </strong>To analyze recent trends in U.S. breast cancer mortality rates by age group and race and ethnicity.</p><p><strong>Methods: </strong>This retrospective analysis of female breast cancer mortality rates used National Center for Health Statistics data from 1990 to 2022 for all women, by age group, and by race or ethnicity. Joinpoint analysis assessed trends in breast cancer mortality rates.</p><p><strong>Results: </strong>Breast cancer mortality rates for women 20 to 39 years old decreased 2.8% per year from 1999 to 2010 but showed no decline from 2010 to 2022 (annual percentage change [APC], -0.01; P = .98). For women of ages 40 to 74 years, breast cancer mortality rates decreased 1.7% to 3.9% per year from 1990 to 2022 (P <.001); a decline was found for all cohorts in this age group except Asian women. For women ≥75 years of age, breast cancer mortality rates declined significantly from 1993 to 2013 (APC, -1.26; P = .01) but showed no evidence of decline from 2013 to 2022 (APC, -0.2; P = .24). Across all ages, breast cancer mortality rates declined for White and Black women but not for Asian, Hispanic, and Native American women. Asian women ≥75 years of age had significantly increasing mortality rates (APC, 0.73; P <.001). For 2004 to 2022, breast cancer mortality rates were 39% higher in Black women than White women and varied strongly by age group: 104% for ages 20 to 39 years, 51% for ages 40 to 74 years, and 13% for ages ≥75 years.</p><p><strong>Conclusion: </strong>Female breast cancer mortality rates have stopped declining in women <40 years of age and >74 years of age. The higher mortality rates in Black women compared with White women are age dependent and substantially higher in younger women.</p>","PeriodicalId":43134,"journal":{"name":"Journal of Breast Imaging","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mathematical Modeling to Address Questions in Breast Cancer Screening: An Overview of the Breast Cancer Models of the Cancer Intervention and Surveillance Modeling Network.
IF 2 Q3 ONCOLOGY Pub Date : 2025-02-26 DOI: 10.1093/jbi/wbaf003
Oguzhan Alagoz, Jennifer L Caswell-Jin, Harry J de Koning, Hui Huang, Xuelin Huang, Sandra J Lee, Yisheng Li, Sylvia K Plevritis, Swarnavo Sarkar, Clyde B Schechter, Natasha K Stout, Amy Trentham-Dietz, Nicolien van Ravesteyn, Kathryn P Lowry

The National Cancer Institute-funded Cancer Intervention and Surveillance Modeling Network (CISNET) breast cancer mathematical models have been increasingly utilized by policymakers to address breast cancer screening policy decisions and influence clinical practice. These well-established and validated models have a successful track record of use in collaborations spanning over 2 decades. While mathematical modeling is a valuable approach to translate short-term screening performance data into long-term breast cancer outcomes, it is inherently complex and requires numerous inputs to approximate the impacts of breast cancer screening. This review article describes the 6 independently developed CISNET breast cancer models, with a particular focus on how they represent breast cancer screening and estimate the contribution of screening to breast cancer mortality reduction and improvements in life expectancy. We also describe differences in structures and assumptions across the models and how variation in model results can highlight areas of uncertainty. Finally, we offer insight into how the results generated by the models can be used to aid decision-making regarding breast cancer screening policy.

{"title":"Mathematical Modeling to Address Questions in Breast Cancer Screening: An Overview of the Breast Cancer Models of the Cancer Intervention and Surveillance Modeling Network.","authors":"Oguzhan Alagoz, Jennifer L Caswell-Jin, Harry J de Koning, Hui Huang, Xuelin Huang, Sandra J Lee, Yisheng Li, Sylvia K Plevritis, Swarnavo Sarkar, Clyde B Schechter, Natasha K Stout, Amy Trentham-Dietz, Nicolien van Ravesteyn, Kathryn P Lowry","doi":"10.1093/jbi/wbaf003","DOIUrl":"https://doi.org/10.1093/jbi/wbaf003","url":null,"abstract":"<p><p>The National Cancer Institute-funded Cancer Intervention and Surveillance Modeling Network (CISNET) breast cancer mathematical models have been increasingly utilized by policymakers to address breast cancer screening policy decisions and influence clinical practice. These well-established and validated models have a successful track record of use in collaborations spanning over 2 decades. While mathematical modeling is a valuable approach to translate short-term screening performance data into long-term breast cancer outcomes, it is inherently complex and requires numerous inputs to approximate the impacts of breast cancer screening. This review article describes the 6 independently developed CISNET breast cancer models, with a particular focus on how they represent breast cancer screening and estimate the contribution of screening to breast cancer mortality reduction and improvements in life expectancy. We also describe differences in structures and assumptions across the models and how variation in model results can highlight areas of uncertainty. Finally, we offer insight into how the results generated by the models can be used to aid decision-making regarding breast cancer screening policy.</p>","PeriodicalId":43134,"journal":{"name":"Journal of Breast Imaging","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effective Integration of Feedback in Breast Imaging: A "Guide for the Trainee".
IF 2 Q3 ONCOLOGY Pub Date : 2025-02-22 DOI: 10.1093/jbi/wbae095
Joshua A Greenstein, Martha Sevenich, Allison Aripoli

Receiving feedback can sometimes be difficult and uncomfortable but is an essential component of professional development in breast imaging. Trainees have an opportunity to leverage feedback in breast imaging by incorporating self-assessments, real-world patient outcomes, procedural feedback, patient interactions, and available audit data to build confidence and competency in residency and fellowship. We present strategies for seeking and receiving feedback with a growth mindset, including specific scenarios in breast imaging where trainees can incorporate feedback and maximize learning potential.

接受反馈有时会让人感到困难和不适,但却是乳腺成像专业发展的重要组成部分。学员有机会通过自我评估、真实世界的患者结果、手术反馈、患者互动以及可用的审计数据来利用乳腺成像中的反馈,从而在住院医师和研究员培训中建立信心和能力。我们介绍了以成长心态寻求和接受反馈的策略,包括乳腺成像中学员可以采纳反馈并最大限度发挥学习潜力的具体场景。
{"title":"Effective Integration of Feedback in Breast Imaging: A \"Guide for the Trainee\".","authors":"Joshua A Greenstein, Martha Sevenich, Allison Aripoli","doi":"10.1093/jbi/wbae095","DOIUrl":"https://doi.org/10.1093/jbi/wbae095","url":null,"abstract":"<p><p>Receiving feedback can sometimes be difficult and uncomfortable but is an essential component of professional development in breast imaging. Trainees have an opportunity to leverage feedback in breast imaging by incorporating self-assessments, real-world patient outcomes, procedural feedback, patient interactions, and available audit data to build confidence and competency in residency and fellowship. We present strategies for seeking and receiving feedback with a growth mindset, including specific scenarios in breast imaging where trainees can incorporate feedback and maximize learning potential.</p>","PeriodicalId":43134,"journal":{"name":"Journal of Breast Imaging","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimizing Screening Outcomes: A Guide for Breast Imaging Practices.
IF 2 Q3 ONCOLOGY Pub Date : 2025-02-20 DOI: 10.1093/jbi/wbae093
Sora C Yoon, Jay A Baker, Lars J Grimm

Radiologists face a range of challenges to maximize the life-saving benefits of screening mammography, including pressure to maintain accuracy, manage heavy workloads, and minimize the risk of fatigue and burnout. This review provides targeted strategies to address these challenges and, ultimately, to improve interpretive performance of screening mammography. Workflow optimizations, including offline vs online and batched vs nonbatched interpretation, interrupted vs uninterrupted reading, and the importance of comparing current mammograms with prior examinations will be explored. Each strategy has strengths, weaknesses, and logistical challenges that must be tailored to the individual practice environment. Moreover, as breast radiologists contend with increasingly busy and hectic working conditions, practical solutions to protect reading environments and minimize distractions, such as the "sterile cockpit" approach, will be described. Additionally, breast radiologists are at greater risk for fatigue and burnout due to rising clinic volumes and an inadequate workforce. Optimizing the approach to reading screens is critical to helping breast imaging radiologists maintain and maximize the benefits of screening mammography, ensure the best outcomes for our patients, and maintain radiologist job satisfaction.

{"title":"Optimizing Screening Outcomes: A Guide for Breast Imaging Practices.","authors":"Sora C Yoon, Jay A Baker, Lars J Grimm","doi":"10.1093/jbi/wbae093","DOIUrl":"https://doi.org/10.1093/jbi/wbae093","url":null,"abstract":"<p><p>Radiologists face a range of challenges to maximize the life-saving benefits of screening mammography, including pressure to maintain accuracy, manage heavy workloads, and minimize the risk of fatigue and burnout. This review provides targeted strategies to address these challenges and, ultimately, to improve interpretive performance of screening mammography. Workflow optimizations, including offline vs online and batched vs nonbatched interpretation, interrupted vs uninterrupted reading, and the importance of comparing current mammograms with prior examinations will be explored. Each strategy has strengths, weaknesses, and logistical challenges that must be tailored to the individual practice environment. Moreover, as breast radiologists contend with increasingly busy and hectic working conditions, practical solutions to protect reading environments and minimize distractions, such as the \"sterile cockpit\" approach, will be described. Additionally, breast radiologists are at greater risk for fatigue and burnout due to rising clinic volumes and an inadequate workforce. Optimizing the approach to reading screens is critical to helping breast imaging radiologists maintain and maximize the benefits of screening mammography, ensure the best outcomes for our patients, and maintain radiologist job satisfaction.</p>","PeriodicalId":43134,"journal":{"name":"Journal of Breast Imaging","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mammography Home Workstations and Remote Diagnostic Breast Imaging: Current Practice Patterns and Planned Future Directions.
IF 2 Q3 ONCOLOGY Pub Date : 2025-02-03 DOI: 10.1093/jbi/wbae087
Ria Dawar, Lars J Grimm, Emily B Sonnenblick, Brian N Dontchos, Kristen Coffey, Sally Goudreau, Beatriu Reig, Sarah A Jacobs, Zeeshan Shah, Lisa Mullen, Vandana Dialani, Reema Dawar, James Sayre, Katerina Dodelzon, Jay R Parikh, Hannah S Milch

Objective: Assess current practices and plans regarding home workstations and remote diagnostic breast imaging in the United States.

Methods: A 43-question survey relating to remote breast imaging was distributed to Society of Breast Imaging members from July 6, 2023, through August 2, 2023. A descriptive summary of responses was performed. Pearson's chi-squared test was used to compare demographic variables of respondents and questions of interest.

Results: In total, 424 surveys were completed (response rate 13%, 424/3244). One-third of breast imaging radiologists (31%, 132/424) reported reading examinations from home or a personal remote site for a median of 25% of their clinical time. The most common types of examinations read from home were screening mammography (90%, 119/132), screening US (58%, 77/132), diagnostic mammography and MRI (both 53%, 70/132), and diagnostic US (49%, 65/132). Respondents from private practices were more likely than those from academic practices to read diagnostic imaging from home (67%, 35/52 vs 29%, 15/52; P <.001). Respondents practicing in the West were less likely to read breast imaging examinations from home compared with those in other geographic regions (18%, 12/67 vs 28%-43% for other regions; P = .023). No differences were found among respondents' overall use of home workstations based on age, gender, or having dependents. Most respondents (75%, 318/424) felt that remote breast reading would be a significant practice pattern in the future.

Conclusion: Home workstations for mammography and remote diagnostic breast imaging are a considerable U.S. practice pattern. Further research should explore radiologist preferences regarding remote breast imaging and its impact on clinical care and radiologist well-being.

{"title":"Mammography Home Workstations and Remote Diagnostic Breast Imaging: Current Practice Patterns and Planned Future Directions.","authors":"Ria Dawar, Lars J Grimm, Emily B Sonnenblick, Brian N Dontchos, Kristen Coffey, Sally Goudreau, Beatriu Reig, Sarah A Jacobs, Zeeshan Shah, Lisa Mullen, Vandana Dialani, Reema Dawar, James Sayre, Katerina Dodelzon, Jay R Parikh, Hannah S Milch","doi":"10.1093/jbi/wbae087","DOIUrl":"https://doi.org/10.1093/jbi/wbae087","url":null,"abstract":"<p><strong>Objective: </strong>Assess current practices and plans regarding home workstations and remote diagnostic breast imaging in the United States.</p><p><strong>Methods: </strong>A 43-question survey relating to remote breast imaging was distributed to Society of Breast Imaging members from July 6, 2023, through August 2, 2023. A descriptive summary of responses was performed. Pearson's chi-squared test was used to compare demographic variables of respondents and questions of interest.</p><p><strong>Results: </strong>In total, 424 surveys were completed (response rate 13%, 424/3244). One-third of breast imaging radiologists (31%, 132/424) reported reading examinations from home or a personal remote site for a median of 25% of their clinical time. The most common types of examinations read from home were screening mammography (90%, 119/132), screening US (58%, 77/132), diagnostic mammography and MRI (both 53%, 70/132), and diagnostic US (49%, 65/132). Respondents from private practices were more likely than those from academic practices to read diagnostic imaging from home (67%, 35/52 vs 29%, 15/52; P <.001). Respondents practicing in the West were less likely to read breast imaging examinations from home compared with those in other geographic regions (18%, 12/67 vs 28%-43% for other regions; P = .023). No differences were found among respondents' overall use of home workstations based on age, gender, or having dependents. Most respondents (75%, 318/424) felt that remote breast reading would be a significant practice pattern in the future.</p><p><strong>Conclusion: </strong>Home workstations for mammography and remote diagnostic breast imaging are a considerable U.S. practice pattern. Further research should explore radiologist preferences regarding remote breast imaging and its impact on clinical care and radiologist well-being.</p>","PeriodicalId":43134,"journal":{"name":"Journal of Breast Imaging","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potential Impact of an Artificial Intelligence-based Mammography Triage Algorithm on Performance and Workload in a Population-based Screening Sample. 基于人工智能的乳腺 X 射线照相术分流算法对人群筛查样本的性能和工作量的潜在影响。
IF 2 Q3 ONCOLOGY Pub Date : 2025-01-25 DOI: 10.1093/jbi/wbae056
Alyssa T Watanabe, Hoanh Vu, Chi Y Chim, Andrew W Litt, Tara Retson, Ray C Mayo

Objective: To evaluate potential screening mammography performance and workload impact using a commercial artificial intelligence (AI)-based triage device in a population-based screening sample.

Methods: In this retrospective study, a sample of 2129 women who underwent screening mammograms were evaluated. The performance of a commercial AI-based triage device was compared with radiologists' reports, actual outcomes, and national benchmarks using commonly used mammography metrics. Up to 5 years of follow-up examination results were evaluated in cases to establish benignity. The algorithm sorted cases into groups of "suspicious" and "low suspicion." A theoretical workload reduction was calculated by subtracting cases triaged as "low suspicion" from the sample.

Results: At the default 93% sensitivity setting, there was significant improvement (P <.05) in the following triage simulation mean performance measures compared with actual outcome: 45.5% improvement in recall rate (13.4% to 7.3%; 95% CI, 6.2-8.3), 119% improvement in positive predictive value (PPV) 1 (5.3% to 11.6%; 95% CI, 9.96-13.4), 28.5% improvement in PPV2 (24.6% to 31.6%; 95% CI, 24.8-39.1), 20% improvement in sensitivity (83.3% to 100%; 95% CI, 100-100), and 7.2% improvement in specificity (87.2% to 93.5%; 95% CI, 92.4-94.5). A theoretical 62.5% workload reduction was possible. At the ultrahigh 99% sensitivity setting, a theoretical 27% workload reduction was possible. No cancers were missed by the algorithm at either sensitivity.

Conclusion: Artificial intelligence-based triage in this simulation demonstrated potential for significant improvement in mammography performance and predicted substantial theoretical workload reduction without any missed cancers.

目的评估基于商业人工智能(AI)的分诊设备在人群筛查样本中的潜在筛查乳腺 X 线照相性能和对工作量的影响:在这项回顾性研究中,对 2129 名接受乳腺 X 光筛查的女性进行了评估。使用常用的乳腺 X 光检查指标,将商用人工智能分流设备的性能与放射科医生的报告、实际结果和国家基准进行了比较。对病例长达 5 年的随访检查结果进行了评估,以确定其良性。该算法将病例分为 "可疑 "和 "低度可疑 "两组。从样本中减去被分流为 "低度可疑 "的病例,计算出理论上减少的工作量:结果:在 93% 的默认灵敏度设置下,工作量有了显著改善(P在该模拟中,基于人工智能的分流技术显示出显著提高乳腺 X 射线照相术性能的潜力,并预测在不遗漏任何癌症的情况下,理论工作量会大幅减少。
{"title":"Potential Impact of an Artificial Intelligence-based Mammography Triage Algorithm on Performance and Workload in a Population-based Screening Sample.","authors":"Alyssa T Watanabe, Hoanh Vu, Chi Y Chim, Andrew W Litt, Tara Retson, Ray C Mayo","doi":"10.1093/jbi/wbae056","DOIUrl":"10.1093/jbi/wbae056","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate potential screening mammography performance and workload impact using a commercial artificial intelligence (AI)-based triage device in a population-based screening sample.</p><p><strong>Methods: </strong>In this retrospective study, a sample of 2129 women who underwent screening mammograms were evaluated. The performance of a commercial AI-based triage device was compared with radiologists' reports, actual outcomes, and national benchmarks using commonly used mammography metrics. Up to 5 years of follow-up examination results were evaluated in cases to establish benignity. The algorithm sorted cases into groups of \"suspicious\" and \"low suspicion.\" A theoretical workload reduction was calculated by subtracting cases triaged as \"low suspicion\" from the sample.</p><p><strong>Results: </strong>At the default 93% sensitivity setting, there was significant improvement (P <.05) in the following triage simulation mean performance measures compared with actual outcome: 45.5% improvement in recall rate (13.4% to 7.3%; 95% CI, 6.2-8.3), 119% improvement in positive predictive value (PPV) 1 (5.3% to 11.6%; 95% CI, 9.96-13.4), 28.5% improvement in PPV2 (24.6% to 31.6%; 95% CI, 24.8-39.1), 20% improvement in sensitivity (83.3% to 100%; 95% CI, 100-100), and 7.2% improvement in specificity (87.2% to 93.5%; 95% CI, 92.4-94.5). A theoretical 62.5% workload reduction was possible. At the ultrahigh 99% sensitivity setting, a theoretical 27% workload reduction was possible. No cancers were missed by the algorithm at either sensitivity.</p><p><strong>Conclusion: </strong>Artificial intelligence-based triage in this simulation demonstrated potential for significant improvement in mammography performance and predicted substantial theoretical workload reduction without any missed cancers.</p>","PeriodicalId":43134,"journal":{"name":"Journal of Breast Imaging","volume":" ","pages":"45-53"},"PeriodicalIF":2.0,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142156257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
External Validation of a Commercial Artificial Intelligence Algorithm on a Diverse Population for Detection of False Negative Breast Cancers. 在不同人群中对商用人工智能算法进行外部验证,以检测假阴性乳腺癌。
IF 2 Q3 ONCOLOGY Pub Date : 2025-01-25 DOI: 10.1093/jbi/wbae058
S Reed Plimpton, Hannah Milch, Christopher Sears, James Chalfant, Anne Hoyt, Cheryce Fischer, William Hsu, Melissa Joines

Objective: There are limited data on the application of artificial intelligence (AI) on nonenriched, real-world screening mammograms. This work aims to evaluate the ability of AI to detect false negative cancers not detected at the time of screening when reviewed by the radiologist alone.

Methods: A commercially available AI algorithm was retrospectively applied to patients undergoing screening full-field digital mammography (FFDM) or digital breast tomosynthesis (DBT) at a single institution from 2010 to 2019. Ground truth was established based on 1-year follow-up data. Descriptive statistics were performed with attention focused on AI detection of false negative cancers within these subsets.

Results: A total of 26 694 FFDM and 3183 DBT examinations were analyzed. Artificial intelligence was able to detect 7/13 false negative cancers (54%) in the FFDM cohort and 4/10 (40%) in the DBT cohort on the preceding screening mammogram that was interpreted as negative by the radiologist. Of these, 4 in the FFDM cohort and 4 in the DBT cohort were identified in breast densities of C or greater. False negative cancers detected by AI were predominantly luminal A invasive malignancies (9/11, 82%). Artificial intelligence was able to detect these false negative cancers a median time of 272 days sooner in the FFDM cohort and 248 days sooner in the DBT cohort compared to the radiologist.

Conclusion: Artificial intelligence was able to detect cancers at the time of screening that were missed by the radiologist. Prospective studies are needed to evaluate the synergy of AI and the radiologist in real-world settings, especially on DBT examinations.

目的:关于人工智能(AI)在非浓缩的真实世界乳房X光筛查中的应用,目前只有有限的数据。这项工作旨在评估人工智能检测筛查时未检测到的假阴性癌症的能力:方法:对2010年至2019年期间在一家机构接受全场数字乳腺X光造影术(FFDM)或数字乳腺断层合成术(DBT)筛查的患者回顾性地应用了一种市售的人工智能算法。根据 1 年的随访数据确定了基本事实。进行了描述性统计,重点关注这些子集中假阴性癌症的人工智能检测:共分析了 26 694 次 FFDM 和 3183 次 DBT 检查。人工智能能够在 FFDM 组群中检测出 7/13 例假阴性癌症(54%),在 DBT 组群中检测出 4/10 例假阴性癌症(40%),这些假阴性癌症是在放射科医生解释为阴性的前一次乳房 X 光筛查中发现的。其中,FFDM 组群中的 4 例和 DBT 组群中的 4 例被确定为乳腺密度为 C 或更高。人工智能检测出的假阴性癌症主要是管腔A型浸润性恶性肿瘤(9/11,82%)。与放射科医生相比,人工智能检测出这些假阴性癌症的中位时间在FFDM队列中提前了272天,在DBT队列中提前了248天:结论:人工智能能够在筛查时发现放射科医生漏诊的癌症。需要进行前瞻性研究,以评估人工智能和放射科医生在实际环境中的协同作用,尤其是在 DBT 检查中。
{"title":"External Validation of a Commercial Artificial Intelligence Algorithm on a Diverse Population for Detection of False Negative Breast Cancers.","authors":"S Reed Plimpton, Hannah Milch, Christopher Sears, James Chalfant, Anne Hoyt, Cheryce Fischer, William Hsu, Melissa Joines","doi":"10.1093/jbi/wbae058","DOIUrl":"10.1093/jbi/wbae058","url":null,"abstract":"<p><strong>Objective: </strong>There are limited data on the application of artificial intelligence (AI) on nonenriched, real-world screening mammograms. This work aims to evaluate the ability of AI to detect false negative cancers not detected at the time of screening when reviewed by the radiologist alone.</p><p><strong>Methods: </strong>A commercially available AI algorithm was retrospectively applied to patients undergoing screening full-field digital mammography (FFDM) or digital breast tomosynthesis (DBT) at a single institution from 2010 to 2019. Ground truth was established based on 1-year follow-up data. Descriptive statistics were performed with attention focused on AI detection of false negative cancers within these subsets.</p><p><strong>Results: </strong>A total of 26 694 FFDM and 3183 DBT examinations were analyzed. Artificial intelligence was able to detect 7/13 false negative cancers (54%) in the FFDM cohort and 4/10 (40%) in the DBT cohort on the preceding screening mammogram that was interpreted as negative by the radiologist. Of these, 4 in the FFDM cohort and 4 in the DBT cohort were identified in breast densities of C or greater. False negative cancers detected by AI were predominantly luminal A invasive malignancies (9/11, 82%). Artificial intelligence was able to detect these false negative cancers a median time of 272 days sooner in the FFDM cohort and 248 days sooner in the DBT cohort compared to the radiologist.</p><p><strong>Conclusion: </strong>Artificial intelligence was able to detect cancers at the time of screening that were missed by the radiologist. Prospective studies are needed to evaluate the synergy of AI and the radiologist in real-world settings, especially on DBT examinations.</p>","PeriodicalId":43134,"journal":{"name":"Journal of Breast Imaging","volume":" ","pages":"16-26"},"PeriodicalIF":2.0,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11770225/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142477137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Utility of Second-Look US to Evaluate Abnormal Molecular Breast Imaging Findings: A Retrospective Study. 二诊 US 对评估异常分子乳腺成像结果的实用性:回顾性研究。
IF 2 Q3 ONCOLOGY Pub Date : 2025-01-25 DOI: 10.1093/jbi/wbae059
Davis C Teichgraeber, Roland L Bassett, Gary J Whitman

Objective: The purpose of this study was to evaluate the utility of US for identifying and characterizing lesions detected on molecular breast imaging (MBI).

Methods: A retrospective single-institution review was performed of patients with MBI studies with subsequent US for abnormal MBI findings between January 1, 2015, and September 30, 2021. Medical records, imaging, and histopathology were reviewed. The reference standard was histopathology and/or imaging follow-up. Associations among MBI findings, the presence of an US correlate, and histopathology were evaluated by Fisher exact tests.

Results: The 32 lesions detected on MBI in 25 patients were evaluated by US, and 19 lesions had an US correlate (19/32, 59%). Mass uptake was more likely to have an US correlate (11/13, 85%; P = .02) than nonmass uptake (7/19, 37%), and mass uptake was more likely to be malignant (5/13, 38%; P = .01). Of the 13 lesions without an US correlate, 5 were evaluated and subsequently biopsied by MRI (2 high-risk lesions and 3 benign lesions). Follow-up MBIs demonstrated stability/resolution for 5 lesions in 4 patients at 6 months or longer. Three patients had no further imaging.

Conclusion: Mass lesions identified on MBI were more likely to have an US correlate and were more likely to be malignant than nonmass lesions.

目的本研究旨在评估 US 在识别和描述分子乳腺成像(MBI)检测到的病变方面的实用性:方法:对2015年1月1日至2021年9月30日期间接受分子乳腺成像检查的患者进行了单机构回顾性研究,随后对异常的分子乳腺成像结果进行了US检查。对病历、影像学和组织病理学进行了审查。参考标准为组织病理学和/或成像随访。通过费舍尔精确检验评估了MBI结果、US相关性和组织病理学之间的关联:结果:25 名患者在 MBI 上发现的 32 个病灶均接受了 US 评估,其中 19 个病灶与 US 相关(19/32,59%)。与非肿块摄取(7/19,37%)相比,肿块摄取更有可能与 US 相关(11/13,85%;P = .02),肿块摄取更有可能是恶性的(5/13,38%;P = .01)。在 13 个没有 US 相关性的病灶中,有 5 个进行了评估,随后通过 MRI 进行了活检(2 个高风险病灶和 3 个良性病灶)。随访 MBI 显示,4 名患者的 5 个病灶在 6 个月或更长时间内稳定/消退。结论:结论:与非肿块病变相比,MBI 发现的肿块病变更有可能与 US 相关,也更有可能是恶性的。
{"title":"The Utility of Second-Look US to Evaluate Abnormal Molecular Breast Imaging Findings: A Retrospective Study.","authors":"Davis C Teichgraeber, Roland L Bassett, Gary J Whitman","doi":"10.1093/jbi/wbae059","DOIUrl":"10.1093/jbi/wbae059","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of this study was to evaluate the utility of US for identifying and characterizing lesions detected on molecular breast imaging (MBI).</p><p><strong>Methods: </strong>A retrospective single-institution review was performed of patients with MBI studies with subsequent US for abnormal MBI findings between January 1, 2015, and September 30, 2021. Medical records, imaging, and histopathology were reviewed. The reference standard was histopathology and/or imaging follow-up. Associations among MBI findings, the presence of an US correlate, and histopathology were evaluated by Fisher exact tests.</p><p><strong>Results: </strong>The 32 lesions detected on MBI in 25 patients were evaluated by US, and 19 lesions had an US correlate (19/32, 59%). Mass uptake was more likely to have an US correlate (11/13, 85%; P = .02) than nonmass uptake (7/19, 37%), and mass uptake was more likely to be malignant (5/13, 38%; P = .01). Of the 13 lesions without an US correlate, 5 were evaluated and subsequently biopsied by MRI (2 high-risk lesions and 3 benign lesions). Follow-up MBIs demonstrated stability/resolution for 5 lesions in 4 patients at 6 months or longer. Three patients had no further imaging.</p><p><strong>Conclusion: </strong>Mass lesions identified on MBI were more likely to have an US correlate and were more likely to be malignant than nonmass lesions.</p>","PeriodicalId":43134,"journal":{"name":"Journal of Breast Imaging","volume":" ","pages":"27-34"},"PeriodicalIF":2.0,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11770226/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142509995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unknown Case: Metastatic Breast Cancer With Abnormal Soft Tissue Mass in the Shoulder. 未知病例:转移性乳腺癌伴肩部异常软组织肿块
IF 2 Q3 ONCOLOGY Pub Date : 2025-01-25 DOI: 10.1093/jbi/wbae005
Colin Marshall, Holly Marshall
{"title":"Unknown Case: Metastatic Breast Cancer With Abnormal Soft Tissue Mass in the Shoulder.","authors":"Colin Marshall, Holly Marshall","doi":"10.1093/jbi/wbae005","DOIUrl":"10.1093/jbi/wbae005","url":null,"abstract":"","PeriodicalId":43134,"journal":{"name":"Journal of Breast Imaging","volume":" ","pages":"119-121"},"PeriodicalIF":2.0,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141318546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Invasive Lobular Carcinoma in the Screening Setting. 浸润性小叶癌的筛查。
IF 2 Q3 ONCOLOGY Pub Date : 2025-01-25 DOI: 10.1093/jbi/wbae082
Beatriu Reig, Laura Heacock

Invasive lobular carcinoma (ILC) is the second-most common histologic subtype of breast cancer, constituting 5% to 15% of all breast cancers. It is characterized by an infiltrating growth pattern that may decrease detectability on mammography and US. The use of digital breast tomosynthesis (DBT) improves conspicuity of ILC, and sensitivity is 80% to 88% for ILC. Sensitivity of mammography is lower in dense breasts, and breast tomosynthesis has better sensitivity for ILC in dense breasts compared with digital mammography (DM). Screening US identifies additional ILCs even after DBT, with a supplemental cancer detection rate of 0 to 1.2 ILC per 1000 examinations. Thirteen percent of incremental cancers found by screening US are ILCs. Breast MRI has a sensitivity of 93% for ILC. Abbreviated breast MRI also has high sensitivity but may be limited due to delayed enhancement in ILC. Contrast-enhanced mammography has improved sensitivity for ILC compared with DM, with higher specificity than breast MRI. In summary, supplemental screening modalities increase detection of ILC, with MRI demonstrating the highest sensitivity.

浸润性小叶癌(ILC)是乳腺癌第二常见的组织学亚型,占所有乳腺癌的5%至15%。它的特点是浸润性生长模式,可能会降低乳房x光检查和超声检查的可检出性。数字乳腺断层合成(DBT)的使用提高了ILC的显著性,ILC的灵敏度为80%至88%。乳腺x线摄影对致密乳腺的敏感性较低,而乳腺断层合成对致密乳腺ILC的敏感性优于数字乳腺x线摄影(DM)。筛查US即使在DBT后也能发现额外的ILC,每1000次检查的补充癌症检出率为0至1.2 ILC。通过筛选US发现的增量癌症中有13%是ILCs。乳腺MRI对ILC的敏感性为93%。缩短乳房MRI也有很高的灵敏度,但可能由于ILC的延迟增强而受到限制。与DM相比,对比增强乳房x线摄影提高了ILC的敏感性,比乳腺MRI具有更高的特异性。总之,补充筛查方式增加了ILC的检测,MRI显示出最高的灵敏度。
{"title":"Invasive Lobular Carcinoma in the Screening Setting.","authors":"Beatriu Reig, Laura Heacock","doi":"10.1093/jbi/wbae082","DOIUrl":"10.1093/jbi/wbae082","url":null,"abstract":"<p><p>Invasive lobular carcinoma (ILC) is the second-most common histologic subtype of breast cancer, constituting 5% to 15% of all breast cancers. It is characterized by an infiltrating growth pattern that may decrease detectability on mammography and US. The use of digital breast tomosynthesis (DBT) improves conspicuity of ILC, and sensitivity is 80% to 88% for ILC. Sensitivity of mammography is lower in dense breasts, and breast tomosynthesis has better sensitivity for ILC in dense breasts compared with digital mammography (DM). Screening US identifies additional ILCs even after DBT, with a supplemental cancer detection rate of 0 to 1.2 ILC per 1000 examinations. Thirteen percent of incremental cancers found by screening US are ILCs. Breast MRI has a sensitivity of 93% for ILC. Abbreviated breast MRI also has high sensitivity but may be limited due to delayed enhancement in ILC. Contrast-enhanced mammography has improved sensitivity for ILC compared with DM, with higher specificity than breast MRI. In summary, supplemental screening modalities increase detection of ILC, with MRI demonstrating the highest sensitivity.</p>","PeriodicalId":43134,"journal":{"name":"Journal of Breast Imaging","volume":" ","pages":"3-15"},"PeriodicalIF":2.0,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Breast Imaging
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1