Russelle Go, Lee Romasanta, Pamela Faye Daza, Darel Alexie David, Luieza Sabello, M. N. Young
At the end of 2019, Coronavirus disease (COVID-19) started and as of now, it is still the number one problem of the world today. This virus can be transmitted through droplets of saliva from an infected person which can be from a sneeze, cough, and exhales. As of now, there are a total of 111 million cases of the virus and there are technologies that were introduced to help in the detection of the infection and to reduce the spread of the virus. One of this technology is the Reverse Transcription-Polymerase Chain Reaction (RT-PCR) Machine. This machine detects any specific genetic material, including a virus. Samples from the body are treated with several chemical solutions which remove substances and only allow Ribonucleic Acid (RNA) to remain. But the problem with this machine is the elicitation of false-positive and false-negative results and certain malfunctions. Due to the issues in using RT-PCR, our team has come up with a newer and improvised version of the machine and called it COVIDBIT. COVIDBIT is a more simplified and portable version of the RT-PCR at a cheaper price. In this study, the team analyzed COVIDBIT as a virus detection device and an alternative for RT-PCR machine using SEM model and found out that there is a significant difference in terms of effectiveness and portability in usage and showed that the 210 respondents from the medical industry are most likely to use these kinds of machine.
{"title":"A Study on COVIDBIT as a COVID-19 Detection Device for an Alternative Reverse Transcription-Polymerase Chain Reaction (RT-PCR) Machine","authors":"Russelle Go, Lee Romasanta, Pamela Faye Daza, Darel Alexie David, Luieza Sabello, M. N. Young","doi":"10.1145/3543081.3543101","DOIUrl":"https://doi.org/10.1145/3543081.3543101","url":null,"abstract":"At the end of 2019, Coronavirus disease (COVID-19) started and as of now, it is still the number one problem of the world today. This virus can be transmitted through droplets of saliva from an infected person which can be from a sneeze, cough, and exhales. As of now, there are a total of 111 million cases of the virus and there are technologies that were introduced to help in the detection of the infection and to reduce the spread of the virus. One of this technology is the Reverse Transcription-Polymerase Chain Reaction (RT-PCR) Machine. This machine detects any specific genetic material, including a virus. Samples from the body are treated with several chemical solutions which remove substances and only allow Ribonucleic Acid (RNA) to remain. But the problem with this machine is the elicitation of false-positive and false-negative results and certain malfunctions. Due to the issues in using RT-PCR, our team has come up with a newer and improvised version of the machine and called it COVIDBIT. COVIDBIT is a more simplified and portable version of the RT-PCR at a cheaper price. In this study, the team analyzed COVIDBIT as a virus detection device and an alternative for RT-PCR machine using SEM model and found out that there is a significant difference in terms of effectiveness and portability in usage and showed that the 210 respondents from the medical industry are most likely to use these kinds of machine.","PeriodicalId":432056,"journal":{"name":"Proceedings of the 6th International Conference on Biomedical Engineering and Applications","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127124715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
What is the essence of thinking? The answer is human consciousness. If human beings do not have the ability to think independently, human beings will not be as advanced and complex as human beings are today, and there will be no countless radicals to explore the truth. Therefore, it is necessary to make a scientific inquiry into our consciousness. It is believed that entropy, as a crucial parameter in thermodynamics, is closely related to human consciousness, and information theory builds a good bridge for this connection. Modern technology has also laid a solid foundation for this, such as fMRI and EEG, to help humans better show the conscious activities in the brain and the relationship with system order. This paper will be divided into three parts one by one: Firstly, this paper outlines the computational framework of dynamic entropy in human brain cognition and nervous system; Then, it come up with two specific branches of research on entropy and human physiological phenomena, namely aging and dreaming with the reference of their corresponding medical treatment, so as to better understand the relationship between entropy and human consciousness. This paper also has the research value in some medical fields regarding to decrease the rate of aging and improve the quality of sleep.
{"title":"Singularity Era: Computational Model of Entropy Within the Human Brain","authors":"Wenyu Ding, Tianyi Chen","doi":"10.1145/3543081.3543091","DOIUrl":"https://doi.org/10.1145/3543081.3543091","url":null,"abstract":"What is the essence of thinking? The answer is human consciousness. If human beings do not have the ability to think independently, human beings will not be as advanced and complex as human beings are today, and there will be no countless radicals to explore the truth. Therefore, it is necessary to make a scientific inquiry into our consciousness. It is believed that entropy, as a crucial parameter in thermodynamics, is closely related to human consciousness, and information theory builds a good bridge for this connection. Modern technology has also laid a solid foundation for this, such as fMRI and EEG, to help humans better show the conscious activities in the brain and the relationship with system order. This paper will be divided into three parts one by one: Firstly, this paper outlines the computational framework of dynamic entropy in human brain cognition and nervous system; Then, it come up with two specific branches of research on entropy and human physiological phenomena, namely aging and dreaming with the reference of their corresponding medical treatment, so as to better understand the relationship between entropy and human consciousness. This paper also has the research value in some medical fields regarding to decrease the rate of aging and improve the quality of sleep.","PeriodicalId":432056,"journal":{"name":"Proceedings of the 6th International Conference on Biomedical Engineering and Applications","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121350235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diabetic Retinopathy (DR) is a multiply occurring complication induced by prolonged course of diabetes. Diabetic Macular Edema (DME) is the most common complication of DR which is the major threat of vision loss. Hence, it is urgently needed to expand the early screening and diagnosis via computer-assisted therapy. However, prior works mainly focus on investigating DR and DME in isolation, largely ignoring their inherent relationships. Besides, the fundus data distribution is typically long-tailed, with tail classes concentrating on critical levels of DME. Motivated by the distinctive complexion above, this work presents a novel position-guided attention block (PGAB) as well as an innovative label-sensitive (LS) loss, which are respectively in charge of extracting position-sensitive features to exploit interactions between hard exudate and macular and encouraging the model to embrace tail classes to lift the accuracy on critical levels of DME. Comprehensive experiments on popular Messidor and IDRiD datasets well demonstrate the superiority of our approach in achieving competitive performance compared to state-of-the-arts.
{"title":"Dealing with Long-tail Issue in Diabetic Retinopathy and Diabetic Macular Edema Grading","authors":"Yuze Xiao, Jianan Li, Shiqi Huang, Ning Shen, Jinhua Zhang, Fengwen Mi, Tingfa Xu","doi":"10.1145/3543081.3543088","DOIUrl":"https://doi.org/10.1145/3543081.3543088","url":null,"abstract":"Diabetic Retinopathy (DR) is a multiply occurring complication induced by prolonged course of diabetes. Diabetic Macular Edema (DME) is the most common complication of DR which is the major threat of vision loss. Hence, it is urgently needed to expand the early screening and diagnosis via computer-assisted therapy. However, prior works mainly focus on investigating DR and DME in isolation, largely ignoring their inherent relationships. Besides, the fundus data distribution is typically long-tailed, with tail classes concentrating on critical levels of DME. Motivated by the distinctive complexion above, this work presents a novel position-guided attention block (PGAB) as well as an innovative label-sensitive (LS) loss, which are respectively in charge of extracting position-sensitive features to exploit interactions between hard exudate and macular and encouraging the model to embrace tail classes to lift the accuracy on critical levels of DME. Comprehensive experiments on popular Messidor and IDRiD datasets well demonstrate the superiority of our approach in achieving competitive performance compared to state-of-the-arts.","PeriodicalId":432056,"journal":{"name":"Proceedings of the 6th International Conference on Biomedical Engineering and Applications","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115347616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this paper, Thermo-Calc and CALPHAD calculation techniques are used to calculate and analyze the multivariate phase diagram, solidification path and microstructure content of biodegradable magnesium alloys with different components. The effects of elements y and Gd on the liquidus, phase distribution, strengthening phase content and microstructure of the alloy were discussed. Under the condition of non-equilibrium solidification, the primary MG24Y5 solid phase decreases and the (MG24Y5+MG3RE_D03) structure increases with the increase of Gd element. With the increase of Y element, the liquidus increased, the solid content of primary MG24Y5 increased, and the structure of (MG24Y5+MG3RE_D03) increased. With the simultaneous increase of Y and Gd elements, the liquidus increased, and the tissue content of (MG24Y5+MG3RE_D03) increased sharply. (MG24Y5+MG41RE5+HCP_A3) the content of residual tissue decreased. Zinc rich phases such as MgZn, MgZn2 and MG2ZN3, with relatively low content, are strengthening phases of solid solution and aging treatment, which play an important role in the mechanical properties of alloy materials. This paper solves the key technical problems of rapid degradation and poor uniformity of degradable magnesium alloy materials, obtains degradable magnesium alloy materials for stents with reliable quality, controllable degradation rate and excellent biocompatibility, forms relevant process standards and technical specifications, and verifies the feasibility of the application of this material technology in cardiovascular stent interventional therapy, Provide material basis and technical support for the further clinical application of the material.
{"title":"Thermodynamic Calculation and Microstructure Optimization of Mg-Gd-Y-Zn-Zr Biodegradable Magnesium Alloy","authors":"Jinjun Tang, Cui Liang, Chenguang Xu","doi":"10.1145/3543081.3543105","DOIUrl":"https://doi.org/10.1145/3543081.3543105","url":null,"abstract":"In this paper, Thermo-Calc and CALPHAD calculation techniques are used to calculate and analyze the multivariate phase diagram, solidification path and microstructure content of biodegradable magnesium alloys with different components. The effects of elements y and Gd on the liquidus, phase distribution, strengthening phase content and microstructure of the alloy were discussed. Under the condition of non-equilibrium solidification, the primary MG24Y5 solid phase decreases and the (MG24Y5+MG3RE_D03) structure increases with the increase of Gd element. With the increase of Y element, the liquidus increased, the solid content of primary MG24Y5 increased, and the structure of (MG24Y5+MG3RE_D03) increased. With the simultaneous increase of Y and Gd elements, the liquidus increased, and the tissue content of (MG24Y5+MG3RE_D03) increased sharply. (MG24Y5+MG41RE5+HCP_A3) the content of residual tissue decreased. Zinc rich phases such as MgZn, MgZn2 and MG2ZN3, with relatively low content, are strengthening phases of solid solution and aging treatment, which play an important role in the mechanical properties of alloy materials. This paper solves the key technical problems of rapid degradation and poor uniformity of degradable magnesium alloy materials, obtains degradable magnesium alloy materials for stents with reliable quality, controllable degradation rate and excellent biocompatibility, forms relevant process standards and technical specifications, and verifies the feasibility of the application of this material technology in cardiovascular stent interventional therapy, Provide material basis and technical support for the further clinical application of the material.","PeriodicalId":432056,"journal":{"name":"Proceedings of the 6th International Conference on Biomedical Engineering and Applications","volume":"396 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123519825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The emerging modern medical technology has provided treatment for a variety of major human diseases (including cancer, cardiovascular and cerebrovascular diseases, diabetes, etc.). However, the long-term control of these chronic diseases remains a challenge. These chronic diseases are the main cause of death and a major burden on public health. One key question in chronic disease management is how to develop efficacious and reliable drugs based on our emerging understanding of disease-related gene expression (from genes to drugs). In contrast, specific medical treatments such as surgery or chemotherapy of cancer often possess a small period over the entire course of chronic disease management, meanwhile the therapy outcomes of chronic diseases also largely depend on the long-term lifestyles of the patients, such as mood and diet. Given the large quantity and complexity of traditional medical data, it is difficult to manually evaluate the impact of diets or nutrition on chronic disease control (from drugs to supplements/nutrition). This project aimed to systematically analyze disease-related gene expression data for drug development and to specify a dietary plan for specific chronic disease recovery from health big data and individualized data of patients. Using multiple gene-to-drug algorithms combined with Random Forest machine learning tools, I have discovered decamethonium bromide as a broad-spectrum anti-cancer drug targeting currently “undruggable” oncogenes and tumor suppressors and investigated honeysuckle as a potential supplement. CCS Concepts· Applied computing · Life and medical sciences · Computational biology
{"title":"Machine-Learning Based Drug and Supplement Design Platform for Chronic Disease Control","authors":"Peter Qi","doi":"10.1145/3543081.3543092","DOIUrl":"https://doi.org/10.1145/3543081.3543092","url":null,"abstract":"The emerging modern medical technology has provided treatment for a variety of major human diseases (including cancer, cardiovascular and cerebrovascular diseases, diabetes, etc.). However, the long-term control of these chronic diseases remains a challenge. These chronic diseases are the main cause of death and a major burden on public health. One key question in chronic disease management is how to develop efficacious and reliable drugs based on our emerging understanding of disease-related gene expression (from genes to drugs). In contrast, specific medical treatments such as surgery or chemotherapy of cancer often possess a small period over the entire course of chronic disease management, meanwhile the therapy outcomes of chronic diseases also largely depend on the long-term lifestyles of the patients, such as mood and diet. Given the large quantity and complexity of traditional medical data, it is difficult to manually evaluate the impact of diets or nutrition on chronic disease control (from drugs to supplements/nutrition). This project aimed to systematically analyze disease-related gene expression data for drug development and to specify a dietary plan for specific chronic disease recovery from health big data and individualized data of patients. Using multiple gene-to-drug algorithms combined with Random Forest machine learning tools, I have discovered decamethonium bromide as a broad-spectrum anti-cancer drug targeting currently “undruggable” oncogenes and tumor suppressors and investigated honeysuckle as a potential supplement. CCS Concepts· Applied computing · Life and medical sciences · Computational biology","PeriodicalId":432056,"journal":{"name":"Proceedings of the 6th International Conference on Biomedical Engineering and Applications","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121406261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Forelimb grasping experiments are important for investigating the performance of the locomotor system and the learning ability. Due to lack of automatic machines, manual operation is a heavy load for experimenters. Therefore, we developed an automatic pellet dispenser using the Arduino Nano board. The user puts a bucket of food pellets into the storage pool, the machine automatically disperses them and delivers a single pellet to a fixed position in the food plate. When the pellet is taken by the animal, then it delivers another. The system is composed of the Arduino Nano board, a stepper motor, two servo motors, two photo sensors, a display and three buttons. It is inexpensive and easy to use. When tested, it ran orderly and stably. We hope it can help in repetitive experiments, reduce the manual load and save a lot of time.
{"title":"Development of an Automatic Pellet Dispenser for Forelimb Grasping Experiments in Rodents","authors":"Shifeng Li, Canhui Zeng, Rongchao Peng, Shan Ma","doi":"10.1145/3543081.3543086","DOIUrl":"https://doi.org/10.1145/3543081.3543086","url":null,"abstract":"Forelimb grasping experiments are important for investigating the performance of the locomotor system and the learning ability. Due to lack of automatic machines, manual operation is a heavy load for experimenters. Therefore, we developed an automatic pellet dispenser using the Arduino Nano board. The user puts a bucket of food pellets into the storage pool, the machine automatically disperses them and delivers a single pellet to a fixed position in the food plate. When the pellet is taken by the animal, then it delivers another. The system is composed of the Arduino Nano board, a stepper motor, two servo motors, two photo sensors, a display and three buttons. It is inexpensive and easy to use. When tested, it ran orderly and stably. We hope it can help in repetitive experiments, reduce the manual load and save a lot of time.","PeriodicalId":432056,"journal":{"name":"Proceedings of the 6th International Conference on Biomedical Engineering and Applications","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124550552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Min Peng, Qiongfang Lv, Hui-wei Liang, Zhijian Zeng, Shao-Kang Huang, Wa Du
Objective Using the optimized method in the technical specification for 《Safety technical specifications for cosmetics 》(2015 Edition), market research was conducted on the addition of 63 prohibited hormone components in the locally marketed products claiming to have skin care effect on children (including cosmetics, class I medical devices and disinfection and sanitation products).Methods Using a column of Shimadzu shim pack XR ODS Ⅲ (2.0 × 150mm, 2.2 μm) , after gradient elution with water acetonitrile as mobile phase, 63 prohibited components were detected by ultra performance liquid chromatography-mass spectrometry (UPLC -MS). Results 63 hormone components were detected in 125 batches of children skin care related products on the market, and none of them was detected. Conclusion The market status of 63 hormone components in the local children cosmetics market is relatively good.
{"title":"Detection, Investigation and Analysis of 63 Hormone Components in Local Children Skin Care Related Products","authors":"Min Peng, Qiongfang Lv, Hui-wei Liang, Zhijian Zeng, Shao-Kang Huang, Wa Du","doi":"10.1145/3543081.3543102","DOIUrl":"https://doi.org/10.1145/3543081.3543102","url":null,"abstract":"Objective Using the optimized method in the technical specification for 《Safety technical specifications for cosmetics 》(2015 Edition), market research was conducted on the addition of 63 prohibited hormone components in the locally marketed products claiming to have skin care effect on children (including cosmetics, class I medical devices and disinfection and sanitation products).Methods Using a column of Shimadzu shim pack XR ODS Ⅲ (2.0 × 150mm, 2.2 μm) , after gradient elution with water acetonitrile as mobile phase, 63 prohibited components were detected by ultra performance liquid chromatography-mass spectrometry (UPLC -MS). Results 63 hormone components were detected in 125 batches of children skin care related products on the market, and none of them was detected. Conclusion The market status of 63 hormone components in the local children cosmetics market is relatively good.","PeriodicalId":432056,"journal":{"name":"Proceedings of the 6th International Conference on Biomedical Engineering and Applications","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126308468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cryptochrome was thought of as a magnetoreceptor based on the proposal that photochemical reactions worked as the sensor of geomagnetic field (GMF). To test the effect of GMF on cryptochrome, we created a hypomagnetic field environment by eliminating the local GMF using Helmholtz coils and grew wild-type Arabidopsis and cryptochrome double mutant, cry1/cry2, in the hypomagnetic field under blue light. We found that hypocotyl length of wild-type Arabidopsis rather than cry1/cry2 mutants was longer in hypomagnetic field than in local GMF. Moreover, we detected gibberellin (GA) levels in Arabidopsis in hypomagnetic field and found that GA4 and GA9 were increased in wild-type seedlings instead of cry1/cry2 mutants. Furthermore, transcription of GA20-oxidase genes (GA20ox1, GA20ox2, and GA20ox3) and GA3-oxidase genes (GA3ox1, GA3ox2, GA3ox3, and GA3ox4) was enhanced. Our results indicate that hypomagnetic field suppresses blue light-dependent inhibition of hypocotyl growth in Arabidopsis, and that cryptochrome and GAs are involved in the effect of hypomagnetic field on hypocotyl growth.
{"title":"Effect of Hypomagnetic Field on Hypocotyl Growth in Arabidopsis","authors":"Shanshan Feng, Chunxiao Xu","doi":"10.1145/3543081.3543089","DOIUrl":"https://doi.org/10.1145/3543081.3543089","url":null,"abstract":"Cryptochrome was thought of as a magnetoreceptor based on the proposal that photochemical reactions worked as the sensor of geomagnetic field (GMF). To test the effect of GMF on cryptochrome, we created a hypomagnetic field environment by eliminating the local GMF using Helmholtz coils and grew wild-type Arabidopsis and cryptochrome double mutant, cry1/cry2, in the hypomagnetic field under blue light. We found that hypocotyl length of wild-type Arabidopsis rather than cry1/cry2 mutants was longer in hypomagnetic field than in local GMF. Moreover, we detected gibberellin (GA) levels in Arabidopsis in hypomagnetic field and found that GA4 and GA9 were increased in wild-type seedlings instead of cry1/cry2 mutants. Furthermore, transcription of GA20-oxidase genes (GA20ox1, GA20ox2, and GA20ox3) and GA3-oxidase genes (GA3ox1, GA3ox2, GA3ox3, and GA3ox4) was enhanced. Our results indicate that hypomagnetic field suppresses blue light-dependent inhibition of hypocotyl growth in Arabidopsis, and that cryptochrome and GAs are involved in the effect of hypomagnetic field on hypocotyl growth.","PeriodicalId":432056,"journal":{"name":"Proceedings of the 6th International Conference on Biomedical Engineering and Applications","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117096332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The aim of this study is to evaluate the effects of pulse rate (i.e., stimulation rate) on Mandarin tone recognition by cochlear implant users. Mandarin tone recognition was measured by using monosyllabic and disyllabic tone data-bases at three pulse rates in cochlear implant users. The three pulse rates included each participant's clinical default pulse rate (i.e., 900 or 1200 pulses per second (pps) for each electrode), 400 pps, and 200 pps. A real-time research speech processor, CCi-Mobile, was used to implement the signal processing strategies. Although the results are variable among participants, there was a trend that the recognition rates of both monosyllabic and disyllabic databases decreased with lower pulse rates, indicating that low pulse rates degrade acoustic cues, like periodicity, for Mandarin tone perception. This study also provided preliminary data for evaluating the CCi-Mobile research processor for the first time in China. The processor could be used for signal processing algorithm development and psychophysical experiments in the future.
{"title":"The Relationship Between Pulse Rate and Mandarin Tone Recognition: A Preliminary Study with CCi-Mobile Cochlear Implant Research Processor","authors":"Yefei Mo, Huali Zhou, Q. Meng, Peina Wu","doi":"10.1145/3543081.3543082","DOIUrl":"https://doi.org/10.1145/3543081.3543082","url":null,"abstract":"The aim of this study is to evaluate the effects of pulse rate (i.e., stimulation rate) on Mandarin tone recognition by cochlear implant users. Mandarin tone recognition was measured by using monosyllabic and disyllabic tone data-bases at three pulse rates in cochlear implant users. The three pulse rates included each participant's clinical default pulse rate (i.e., 900 or 1200 pulses per second (pps) for each electrode), 400 pps, and 200 pps. A real-time research speech processor, CCi-Mobile, was used to implement the signal processing strategies. Although the results are variable among participants, there was a trend that the recognition rates of both monosyllabic and disyllabic databases decreased with lower pulse rates, indicating that low pulse rates degrade acoustic cues, like periodicity, for Mandarin tone perception. This study also provided preliminary data for evaluating the CCi-Mobile research processor for the first time in China. The processor could be used for signal processing algorithm development and psychophysical experiments in the future.","PeriodicalId":432056,"journal":{"name":"Proceedings of the 6th International Conference on Biomedical Engineering and Applications","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116874465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Postpartum rehabilitation is one of the issues that pregnant women are very concerned about. In order to facilitate the postpartum rehabilitation nursing of spontaneous parturients, assist the restoration of uterus and save labor cost, this paper designs a non-invasive and easy to operate portable low-frequency pulse postpartum rehabilitation system to help parturients alleviate their physical and mental pressure and reduce their postpartum discomfort. The system uses stm32f103rct6 as the core controller, takes the belt as the carrier, and combines the pressure control module, temperature control module and low-frequency pulse module. The pressure control module is composed of pressure sensor, airbag and air pump. The temperature control module consists of a temperature sensor and a heating plate. STM32 collects the data of each module for analysis and processing, and transmits the data to mobile app or PC through Bluetooth module. The system can not only realize the functions of low-frequency pulse current massage, pelvic pressurization and dew discharge, temperature control and heat preservation, but also be safe, reliable and practical.
{"title":"Design of a STM32 based Portable System for Postpartum Recovery","authors":"Xiaolin Lu, D. Chen, Shan Ma","doi":"10.1145/3543081.3543083","DOIUrl":"https://doi.org/10.1145/3543081.3543083","url":null,"abstract":"Postpartum rehabilitation is one of the issues that pregnant women are very concerned about. In order to facilitate the postpartum rehabilitation nursing of spontaneous parturients, assist the restoration of uterus and save labor cost, this paper designs a non-invasive and easy to operate portable low-frequency pulse postpartum rehabilitation system to help parturients alleviate their physical and mental pressure and reduce their postpartum discomfort. The system uses stm32f103rct6 as the core controller, takes the belt as the carrier, and combines the pressure control module, temperature control module and low-frequency pulse module. The pressure control module is composed of pressure sensor, airbag and air pump. The temperature control module consists of a temperature sensor and a heating plate. STM32 collects the data of each module for analysis and processing, and transmits the data to mobile app or PC through Bluetooth module. The system can not only realize the functions of low-frequency pulse current massage, pelvic pressurization and dew discharge, temperature control and heat preservation, but also be safe, reliable and practical.","PeriodicalId":432056,"journal":{"name":"Proceedings of the 6th International Conference on Biomedical Engineering and Applications","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123061662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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