Pub Date : 2021-07-01DOI: 10.4103/denthyp.denthyp_166_20
B. Quiceno, Luis A Barrera
Introduction: The purpose of this review is to establish how the theory of complexity is understood and instituted in dentistry. Methods: The stomatognathic system can be understood as a dynamic, complex, and adaptive system. Each pathological or physiological condition of this system involves physical, chemical, and biological processes in constant, open, and changing interactions with social, emotional, nutritional, political, and economic processes. Against this background, specifically, the following research questions were posed: How do researchers use complexity science in dentistry? How is complexity science described in dentistry articles?. Results: A brief literature search was implemented, which identified 11 PubMed articles as well as two from the Literatura Latinoamericana y del Caribe en Ciencias de la Salud (LILACS) database and one from the Cochrane Library for a full text review. Studies on complexity in the dental sciences are mostly presented in the form of critical opinion articles, which corresponded to 50% of the reviewed articles. In dentistry, complexity is understood as less of a theory and more as a line of thinking regarding procedures that can become complex at any given time. Conclusion: This article shows that there are great difficulties in integrating complexity and understanding it in dentistry. There are many aspects from complexity science that still need to be understood in oral health.
{"title":"A Scoping Review of Complexity Science in Dentistry","authors":"B. Quiceno, Luis A Barrera","doi":"10.4103/denthyp.denthyp_166_20","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_166_20","url":null,"abstract":"Introduction: The purpose of this review is to establish how the theory of complexity is understood and instituted in dentistry. Methods: The stomatognathic system can be understood as a dynamic, complex, and adaptive system. Each pathological or physiological condition of this system involves physical, chemical, and biological processes in constant, open, and changing interactions with social, emotional, nutritional, political, and economic processes. Against this background, specifically, the following research questions were posed: How do researchers use complexity science in dentistry? How is complexity science described in dentistry articles?. Results: A brief literature search was implemented, which identified 11 PubMed articles as well as two from the Literatura Latinoamericana y del Caribe en Ciencias de la Salud (LILACS) database and one from the Cochrane Library for a full text review. Studies on complexity in the dental sciences are mostly presented in the form of critical opinion articles, which corresponded to 50% of the reviewed articles. In dentistry, complexity is understood as less of a theory and more as a line of thinking regarding procedures that can become complex at any given time. Conclusion: This article shows that there are great difficulties in integrating complexity and understanding it in dentistry. There are many aspects from complexity science that still need to be understood in oral health.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"12 1","pages":"109 - 117"},"PeriodicalIF":0.5,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43290918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-01DOI: 10.4103/denthyp.denthyp_112_21
F. Abbasi, Ali Moaddabi, Ghazal Beithardan, M. Asnaashari, S. Rezaei, Amirhossein Moaddabi
Introduction Myofascial pain dysfunction syndrome (MPDS) can be a consequence of conditions such as temporomandibular disorders. The aim of this study was to compare the effect of diode laser and ibuprofen to reduce pain and inflammation in patients with MPDS. Methods and materials: In this study, 40 patients with MPDS were randomly divided into two groups. One group received ibuprofen 500 mg two times a day for 3 weeks and had placebo laser sessions. The other group received active laser (diode 810 nm CW) as treatment factor and placebo drug. Pain intensity was measured by visual analog scale and maximum painless mouth opening was also measured as a functional index every session and in a 2-month follow-up. Data were collected and analyzed using independent t test and analysis of variance (α = 0.05). Results Low-level laser group showed a significant reduction in pain and a significant increase in mouth opening. In ibuprofen group, neither pain intensity nor maximum mouth opening had significant improvement. Conclusion Treatment with low-level laser improved mouth opening and pain intensity significantly in patients with MPDS. Therefore, low-level laser can be a good treatment modality for these patients.
{"title":"Comparing the Effects of Low-Level Laser Therapy with Ibuprofen in Improving Myofascial Pain Dysfunction Syndrome","authors":"F. Abbasi, Ali Moaddabi, Ghazal Beithardan, M. Asnaashari, S. Rezaei, Amirhossein Moaddabi","doi":"10.4103/denthyp.denthyp_112_21","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_112_21","url":null,"abstract":"Introduction Myofascial pain dysfunction syndrome (MPDS) can be a consequence of conditions such as temporomandibular disorders. The aim of this study was to compare the effect of diode laser and ibuprofen to reduce pain and inflammation in patients with MPDS. Methods and materials: In this study, 40 patients with MPDS were randomly divided into two groups. One group received ibuprofen 500 mg two times a day for 3 weeks and had placebo laser sessions. The other group received active laser (diode 810 nm CW) as treatment factor and placebo drug. Pain intensity was measured by visual analog scale and maximum painless mouth opening was also measured as a functional index every session and in a 2-month follow-up. Data were collected and analyzed using independent t test and analysis of variance (α = 0.05). Results Low-level laser group showed a significant reduction in pain and a significant increase in mouth opening. In ibuprofen group, neither pain intensity nor maximum mouth opening had significant improvement. Conclusion Treatment with low-level laser improved mouth opening and pain intensity significantly in patients with MPDS. Therefore, low-level laser can be a good treatment modality for these patients.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"12 1","pages":"124 - 127"},"PeriodicalIF":0.5,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45720307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-01DOI: 10.4103/denthyp.denthyp_107_20
E. Rossomando
This paper examines the delivery of oral health care and compares the delivery in 2020 with that before 1900. While equipment and materials have changed, the design of the office, and the use of personnel within the office has remained remarkably similar. The doctor is responsible for diagnosis and treatment with some support services provided by hygienists and assistants. This piece work delivery model contrasts with an assembly line model. The assembly line model is explored here in a hypothetical visit to a dental office in 2025. The paper describes the layout of practice as well as the role of the doctor and auxiliary personnel in the office.
{"title":"The Application of the Assembly Line to the Delivery of Oral Health Care","authors":"E. Rossomando","doi":"10.4103/denthyp.denthyp_107_20","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_107_20","url":null,"abstract":"This paper examines the delivery of oral health care and compares the delivery in 2020 with that before 1900. While equipment and materials have changed, the design of the office, and the use of personnel within the office has remained remarkably similar. The doctor is responsible for diagnosis and treatment with some support services provided by hygienists and assistants. This piece work delivery model contrasts with an assembly line model. The assembly line model is explored here in a hypothetical visit to a dental office in 2025. The paper describes the layout of practice as well as the role of the doctor and auxiliary personnel in the office.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"12 1","pages":"54 - 58"},"PeriodicalIF":0.5,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41479686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-01DOI: 10.4103/denthyp.denthyp_180_20
P. Shetty, Barkha Udhani, Saleem D Makandar, Rabihah Alawi, T. Noorani, N. Jha, Pradeep A. Bapna
Introduction: Coronavirus disease 19 (COVID-19) is a highly contagious and virulent infection caused by severe acute respiratory syndrome coronavirus 2. The symptoms arise within 2 to 14 days after the infection. The specimens are collected from the upper respiratory tract through nasopharyngeal and oropharyngeal swab. This sampling requires close contact with COVID-19 patients and may directly cause transmission to health care professionals. Saliva specimens can be collected easily by asking patients to spit into a sterile container. Materials and Methods: In the current study, the selected patients (n = 20) were those who tested positive for COVID-19 and were admitted to the hospital. After getting approval from ethical committee of the hospital, both nasopharyngeal swab specimens and the salivary samples of each patient were collected and tested using standard procedure of real-time polymerase chain reaction. Results: The mean cycle threshold values obtained from both the sampling techniques were correlated. It was seen that there was no significant difference between them. The advantage of using saliva as a specimen is in the overall specimen collection procedure and its cost and time effectiveness. The diagnosis of COVID-19 through a rapid test procedure using salivary samples could be a boon to dentists. Conclusion: This would help in the detection of positive asymptomatic carriers of the virus among the patients who come to seek dental treatment and reduce the risk of infection in the dental office. The results of this study clearly show that the values obtained from the two sampling techniques are closely related, and hence saliva could definitely be considered as a diagnostic aid for COVID-19.
{"title":"Saliva as a Diagnostic Aid in COVID-19: A Boon for Dentistry","authors":"P. Shetty, Barkha Udhani, Saleem D Makandar, Rabihah Alawi, T. Noorani, N. Jha, Pradeep A. Bapna","doi":"10.4103/denthyp.denthyp_180_20","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_180_20","url":null,"abstract":"Introduction: Coronavirus disease 19 (COVID-19) is a highly contagious and virulent infection caused by severe acute respiratory syndrome coronavirus 2. The symptoms arise within 2 to 14 days after the infection. The specimens are collected from the upper respiratory tract through nasopharyngeal and oropharyngeal swab. This sampling requires close contact with COVID-19 patients and may directly cause transmission to health care professionals. Saliva specimens can be collected easily by asking patients to spit into a sterile container. Materials and Methods: In the current study, the selected patients (n = 20) were those who tested positive for COVID-19 and were admitted to the hospital. After getting approval from ethical committee of the hospital, both nasopharyngeal swab specimens and the salivary samples of each patient were collected and tested using standard procedure of real-time polymerase chain reaction. Results: The mean cycle threshold values obtained from both the sampling techniques were correlated. It was seen that there was no significant difference between them. The advantage of using saliva as a specimen is in the overall specimen collection procedure and its cost and time effectiveness. The diagnosis of COVID-19 through a rapid test procedure using salivary samples could be a boon to dentists. Conclusion: This would help in the detection of positive asymptomatic carriers of the virus among the patients who come to seek dental treatment and reduce the risk of infection in the dental office. The results of this study clearly show that the values obtained from the two sampling techniques are closely related, and hence saliva could definitely be considered as a diagnostic aid for COVID-19.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"12 1","pages":"87 - 90"},"PeriodicalIF":0.5,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42287777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-01DOI: 10.4103/denthyp.denthyp_62_20
S. C, S. J, N. AlMansour, Saleh Almalaq, F. Alnasrallah, T. Alshammari, Mohammad Alshammari, A. Nayyar
Introduction: Regardless of potent anti-microbial and anti-plaque properties of Chlorhexidine (CHX), its widespread and comprehensive uses are restricted by local side effects which are mostly dose dependent. Thus, by understanding the properties and limitations of the CHX molecule, consideration has been given to CHX with lower concentrations, though, this, may produce an impact on its activity emphasizing the need for further clinical trials. The present study was, thus, designed to assess and compare the efficacy of commercially available 0.12% (Periogard) and 0.2% (Hexidine) of CHX mouthrinses on dental plaque and gingiva over a period of eight weeks. Materials and Methods: A randomized control, triple blind parallel clinical trial was designed among ninety-nine subjects. The study subjects were randomly distributed into three groups with random allocation of mouthrinses to each group. Plaque and gingival indices were recorded by using Plaque and Gingival indices were recorded by using Turesky, Gilmore and Glickman’s modification of Quigley Hein Plaque Index and Loe and Silness Gingival Index. Statistical analysis was done using IBM SPSS Statistics for Windows version 21 (IBM Corp, Armonk, USA). Wilcoxon matched pairs signed rank test was applied to compare reduction in mean plaque scores and mean gingival scores at different time intervals while pair-wise comparison in between the groups was done by using Mann-Whitney U test. P < 0.05 was considered as statistically significant. Results: Both the 0.2% and 0.12% CHX mouthrinses were effective in controlling plaque and gingivitis over a period of eight weeks. These mouthrinses exhibited significant decreases in mean plaque and gingival scores during baseline to 4th week examination, however, a significant rise in mean plaque and gingival score was noted again from 4th week to 8th week examination. Conclusion: The study concluded that lower concentrations of CHX (0.12%) are as effective as 0.2% of CHX, thereby, use of lower concentrations of CHX can be recommended.
简介：尽管氯己定具有强大的抗微生物和抗牙菌斑特性，但其广泛和全面的应用受到局部副作用的限制，这些副作用大多依赖于剂量。因此，通过了解CHX分子的性质和局限性，已经考虑使用较低浓度的CHX，尽管这可能会对其活性产生影响，强调需要进一步的临床试验。因此，本研究旨在评估和比较市售0.12%（Periogard）和0.2%（Hexidine）CHX漱口液在八周内对牙菌斑和牙龈的疗效。材料和方法：在99名受试者中设计了一项随机对照、三盲平行临床试验。研究对象被随机分为三组，每组随机分配漱口液。牙菌斑和牙龈指数用牙菌斑记录，牙龈指数用Turesky、Gilmore和Glickman对Quigley-Hein牙菌斑指数和Loe和Silness牙龈指数的修正记录。使用IBM SPSS Statistics for Windows version 21（IBM Corp，Armonk，USA）进行统计分析。Wilcoxon配对符号秩检验用于比较不同时间间隔的平均牙菌斑得分和平均牙龈得分的减少，而两组之间的配对比较则通过Mann-Whitney U检验进行。P＜0.05具有统计学意义。结果：0.2%和0.12%CHX漱口液在8周内均能有效控制牙菌斑和牙龈炎。在基线检查至第4周检查期间，这些漱口液的平均牙菌斑和牙龈得分显著降低，然而，在第4周至第8周检查期间再次注意到平均牙菌斑和齿龈得分显著升高。结论：本研究得出的结论是，较低浓度的CHX（0.12%）与0.2%的CHX一样有效，因此可以推荐使用较低浓度CHX。
{"title":"Comparison of Commercially Available 0.12% And 0.2% Chlorhexidine Mouthrinses on Plaque and Gingiva: A Randomized Controlled Trial","authors":"S. C, S. J, N. AlMansour, Saleh Almalaq, F. Alnasrallah, T. Alshammari, Mohammad Alshammari, A. Nayyar","doi":"10.4103/denthyp.denthyp_62_20","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_62_20","url":null,"abstract":"Introduction: Regardless of potent anti-microbial and anti-plaque properties of Chlorhexidine (CHX), its widespread and comprehensive uses are restricted by local side effects which are mostly dose dependent. Thus, by understanding the properties and limitations of the CHX molecule, consideration has been given to CHX with lower concentrations, though, this, may produce an impact on its activity emphasizing the need for further clinical trials. The present study was, thus, designed to assess and compare the efficacy of commercially available 0.12% (Periogard) and 0.2% (Hexidine) of CHX mouthrinses on dental plaque and gingiva over a period of eight weeks. Materials and Methods: A randomized control, triple blind parallel clinical trial was designed among ninety-nine subjects. The study subjects were randomly distributed into three groups with random allocation of mouthrinses to each group. Plaque and gingival indices were recorded by using Plaque and Gingival indices were recorded by using Turesky, Gilmore and Glickman’s modification of Quigley Hein Plaque Index and Loe and Silness Gingival Index. Statistical analysis was done using IBM SPSS Statistics for Windows version 21 (IBM Corp, Armonk, USA). Wilcoxon matched pairs signed rank test was applied to compare reduction in mean plaque scores and mean gingival scores at different time intervals while pair-wise comparison in between the groups was done by using Mann-Whitney U test. P < 0.05 was considered as statistically significant. Results: Both the 0.2% and 0.12% CHX mouthrinses were effective in controlling plaque and gingivitis over a period of eight weeks. These mouthrinses exhibited significant decreases in mean plaque and gingival scores during baseline to 4th week examination, however, a significant rise in mean plaque and gingival score was noted again from 4th week to 8th week examination. Conclusion: The study concluded that lower concentrations of CHX (0.12%) are as effective as 0.2% of CHX, thereby, use of lower concentrations of CHX can be recommended.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"12 1","pages":"59 - 66"},"PeriodicalIF":0.5,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46002501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-01DOI: 10.4103/denthyp.denthyp_153_20
Melissa Tionardus, I Gusti Ngurah Agung Dwija Putra, N. Ulfah, A. Krismariono, E. Setiawatie, C. Prahasanti
Introduction: Collagen peptide extracted from gouramy fish scale has noncytotoxic effects and good viability on osteoblast cells. Various characteristic tests also show that it could form as scaffold with the potential to be a biomaterial graft used in tissue engineering. Studies in this field are vital considering the fact that graft is highly essential for the development and success of regeneration therapy. The aim of the study was to examine the expression of alkaline phosphatase (ALP) and transforming growth factor-β (TGF-β) in osteoblast cell cultures after administering collagen peptide derived from gouramy fish scale. Material and Methods: Osteoblast cells were put into 60 well plates divided into two groups. The first group was to analyze the expression of ALP, while the second group was for TGF-β. Then, each of the group was divided into five other groups consisting of cell control and culture of osteoblast cell having collagen peptide derived from gouramy fish scale with four different concentrations. The collagen peptide was extracted through enzymatic method. Then, the immunocytochemistry assay was used to detect the expression of ALP and TGF-β in the osteoblast cell cultures derived from calvaria mice after administering collagen peptide from the fish scale. The statistical methods used include Multivariate Analysisof Variance (MANOVA) analysis with a significance value of 0.000 (P < 0.05) and Tukey Honest Significance Test (HSD). Results: The statistical results showed that the collagen peptide derived from gouramy fish scales with various concentrations produced significantly different expressions of ALP and TGF-β. Conclusion: The expression of ALP and TGF-β in osteoblast cell cultures increased after administering the collagen peptide derived from the gouramy fish scales.
{"title":"Expression of ALP and TGF-β in Osteoblast Cell Cultures after Administering Collagen Peptide Derived from Gouramy (Osphronemus goramy) Fish Scales","authors":"Melissa Tionardus, I Gusti Ngurah Agung Dwija Putra, N. Ulfah, A. Krismariono, E. Setiawatie, C. Prahasanti","doi":"10.4103/denthyp.denthyp_153_20","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_153_20","url":null,"abstract":"Introduction: Collagen peptide extracted from gouramy fish scale has noncytotoxic effects and good viability on osteoblast cells. Various characteristic tests also show that it could form as scaffold with the potential to be a biomaterial graft used in tissue engineering. Studies in this field are vital considering the fact that graft is highly essential for the development and success of regeneration therapy. The aim of the study was to examine the expression of alkaline phosphatase (ALP) and transforming growth factor-β (TGF-β) in osteoblast cell cultures after administering collagen peptide derived from gouramy fish scale. Material and Methods: Osteoblast cells were put into 60 well plates divided into two groups. The first group was to analyze the expression of ALP, while the second group was for TGF-β. Then, each of the group was divided into five other groups consisting of cell control and culture of osteoblast cell having collagen peptide derived from gouramy fish scale with four different concentrations. The collagen peptide was extracted through enzymatic method. Then, the immunocytochemistry assay was used to detect the expression of ALP and TGF-β in the osteoblast cell cultures derived from calvaria mice after administering collagen peptide from the fish scale. The statistical methods used include Multivariate Analysisof Variance (MANOVA) analysis with a significance value of 0.000 (P < 0.05) and Tukey Honest Significance Test (HSD). Results: The statistical results showed that the collagen peptide derived from gouramy fish scales with various concentrations produced significantly different expressions of ALP and TGF-β. Conclusion: The expression of ALP and TGF-β in osteoblast cell cultures increased after administering the collagen peptide derived from the gouramy fish scales.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"12 1","pages":"73 - 78"},"PeriodicalIF":0.5,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42406122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-01DOI: 10.4103/denthyp.denthyp_123_20
Lina M. Escobar, H. Rodríguez, J. Castellanos
Introduction: Attention-deficit/hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder in children and can persist until adulthood. This disorder negatively affects almost all personal, academic, and work fields and often strains parent-child relationships. On the other hand, obstructive sleep apnea (OSA) is characterized by episodes of partial or complete obstruction of the upper airway during sleep. Some studies have suggested an association between OSA and ADHD in children and adults. The Hypothesis: It has been suggested that therapeutic intervention in OSA has a significant improvement in abnormal behaviors such as hyperactivity, inattention, and aggression, and in cognitive and school performance. OSA can lead to ADHD-like symptoms that disappear when OSA is sufficiently treated. The use of oral appliance therapy (OAT) is being studied as a method to control OSA. We hypothesize that the management of OSA with OAT could reduce ADHD symptoms. Evaluation of the Hypothesis: In patients who present with OSA and ADHD simultaneously, it should be evaluated whether the treatment of OSA with the use of OAT as rapid maxillary expansion devices or oral mandibular advancement devices reduces the symptoms of both OSA and ADHD, which would allow the establishment of an alternative method of treatment for both pathologies that is less invasive and less expensive.
{"title":"Attention-Deficit/Hyperactivity Disorder Symptoms can be Reduced by Effectively Treating Obstructive Sleep Apnea with Oral Appliances: A Hypothesis","authors":"Lina M. Escobar, H. Rodríguez, J. Castellanos","doi":"10.4103/denthyp.denthyp_123_20","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_123_20","url":null,"abstract":"Introduction: Attention-deficit/hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder in children and can persist until adulthood. This disorder negatively affects almost all personal, academic, and work fields and often strains parent-child relationships. On the other hand, obstructive sleep apnea (OSA) is characterized by episodes of partial or complete obstruction of the upper airway during sleep. Some studies have suggested an association between OSA and ADHD in children and adults. The Hypothesis: It has been suggested that therapeutic intervention in OSA has a significant improvement in abnormal behaviors such as hyperactivity, inattention, and aggression, and in cognitive and school performance. OSA can lead to ADHD-like symptoms that disappear when OSA is sufficiently treated. The use of oral appliance therapy (OAT) is being studied as a method to control OSA. We hypothesize that the management of OSA with OAT could reduce ADHD symptoms. Evaluation of the Hypothesis: In patients who present with OSA and ADHD simultaneously, it should be evaluated whether the treatment of OSA with the use of OAT as rapid maxillary expansion devices or oral mandibular advancement devices reduces the symptoms of both OSA and ADHD, which would allow the establishment of an alternative method of treatment for both pathologies that is less invasive and less expensive.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"12 1","pages":"99 - 103"},"PeriodicalIF":0.5,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42118032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-01DOI: 10.4103/denthyp.denthyp_80_21
Jafar Kolahi, D. Dunning, P. Iranmanesh, M. Tofanghchiha
{"title":"Dental Articles Shared the Most in Twittersphere in 2020","authors":"Jafar Kolahi, D. Dunning, P. Iranmanesh, M. Tofanghchiha","doi":"10.4103/denthyp.denthyp_80_21","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_80_21","url":null,"abstract":"","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"12 1","pages":"51 - 53"},"PeriodicalIF":0.5,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48637446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-01DOI: 10.4103/denthyp.denthyp_172_20
A. Fouad, Fatimah Patel, M. Al-Thagafi, Mawed Yahya, M. Roshdy
Introduction: Breast cancer (BC) is a public health problem and the most frequent malignancy among women. Oral health is important and directly related to the overall general health of the body; it is dependent and related to oral health knowledge and oral hygiene behavior. Several studies have associated links between BC and periodontal disease (PD). The aim of the study was to assess oral health and periodontal disease awareness and potential risk factors of BC in a sample of Jeddah residents. Materials and Methods: A cross-sectional study was conducted on 106 adults with a self-answered questionnaire in the framework of a community service initiative sponsored by the Ministry of Health on the occasion of the world BC month, where the college students participated in. Results: In our study population, 68.68% of participants expressed proper oral hygiene awareness, while merely 42.72% identified the correct risk factors of BC. Only 12.3% had awareness of PD as a potential risk factor of BC, and their awareness was measured against their oral hygiene and periodontal health awareness, where 92.3% acknowledged the negative effect of oral hygiene neglect on the overall body health, 76.9% heard of dental plaque biofilm, and only 23.1% identified it as the causative of PD. Finally, 61.5% cleaned their teeth twice a day in accordance with the recommendations of the Saudi Dental Society. Conclusion: There is an urgent need for comprehensive educational programs to promote correct oral hygiene practice and educate on its positive impact on the overall body health. The knowledge and awareness on BC and PD can still rise by community services and awareness campaigns throughout the city of Jeddah.
{"title":"Patient Awareness of Oral Health and Periodontal Disease as a Potential Risk Factor of Breast Cancer","authors":"A. Fouad, Fatimah Patel, M. Al-Thagafi, Mawed Yahya, M. Roshdy","doi":"10.4103/denthyp.denthyp_172_20","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_172_20","url":null,"abstract":"Introduction: Breast cancer (BC) is a public health problem and the most frequent malignancy among women. Oral health is important and directly related to the overall general health of the body; it is dependent and related to oral health knowledge and oral hygiene behavior. Several studies have associated links between BC and periodontal disease (PD). The aim of the study was to assess oral health and periodontal disease awareness and potential risk factors of BC in a sample of Jeddah residents. Materials and Methods: A cross-sectional study was conducted on 106 adults with a self-answered questionnaire in the framework of a community service initiative sponsored by the Ministry of Health on the occasion of the world BC month, where the college students participated in. Results: In our study population, 68.68% of participants expressed proper oral hygiene awareness, while merely 42.72% identified the correct risk factors of BC. Only 12.3% had awareness of PD as a potential risk factor of BC, and their awareness was measured against their oral hygiene and periodontal health awareness, where 92.3% acknowledged the negative effect of oral hygiene neglect on the overall body health, 76.9% heard of dental plaque biofilm, and only 23.1% identified it as the causative of PD. Finally, 61.5% cleaned their teeth twice a day in accordance with the recommendations of the Saudi Dental Society. Conclusion: There is an urgent need for comprehensive educational programs to promote correct oral hygiene practice and educate on its positive impact on the overall body health. The knowledge and awareness on BC and PD can still rise by community services and awareness campaigns throughout the city of Jeddah.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"12 1","pages":"79 - 86"},"PeriodicalIF":0.5,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45603808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-01DOI: 10.4103/denthyp.denthyp_183_20
K. Murdiastuti, Niken Olivia, Wiwin-winda Kusumadewi, Nandini Sumito
Introduction: Platelet-rich plasma (PRP) is paid attention for regenerative therapy because it clinically improves neoangiogenesis and periodontal regeneration. PRP can be made in form of homologous PRP (HPRP) from healthy, screened, and habitual blood donors and freeze-dried to increase stored time of HPRP and maintain growth factors. The purpose of this study is to evaluate freeze-dried homologous platelet-rich plasma (FD HPRP) on osteogenesis. Material and Methods: HPRP was taken from the blood bank and then a freeze-drying and γ-radiation process was carried out with doses of 20 and 25 KGy, respectively, for the sterilization. Blood was collected as much as 10 mL and then centrifuged at 700 rpm for 3 minutes to produce injectable platelet-rich fibrin (iPRF) as a positive control. Cell line MG63 were cultured to confluent, and then treated with FD HPRP 20 kGy, FD HPRP 25 kGy, iPRF, and one group non treated as a negative control. Osteocytes were determined based on morphology after hematoxylin staining to see the differentiation process. The data were analyzed using one-way analysis of variance (ANOVA). Results: There was a significant difference in the number of osteocytes between FD HPRP and negative control (P < 0.05). The number of osteocytes FD HPRP 25 was higher than FD HPRP 20. Conclusion: The present results indicate that FD HPRP could support the bone regeneration and used without any preparation like fresh PRP.
{"title":"In Vitro Osteogenic Potential of Freeze-Dried Homologous Platelet-Rich Plasma","authors":"K. Murdiastuti, Niken Olivia, Wiwin-winda Kusumadewi, Nandini Sumito","doi":"10.4103/denthyp.denthyp_183_20","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_183_20","url":null,"abstract":"Introduction: Platelet-rich plasma (PRP) is paid attention for regenerative therapy because it clinically improves neoangiogenesis and periodontal regeneration. PRP can be made in form of homologous PRP (HPRP) from healthy, screened, and habitual blood donors and freeze-dried to increase stored time of HPRP and maintain growth factors. The purpose of this study is to evaluate freeze-dried homologous platelet-rich plasma (FD HPRP) on osteogenesis. Material and Methods: HPRP was taken from the blood bank and then a freeze-drying and γ-radiation process was carried out with doses of 20 and 25 KGy, respectively, for the sterilization. Blood was collected as much as 10 mL and then centrifuged at 700 rpm for 3 minutes to produce injectable platelet-rich fibrin (iPRF) as a positive control. Cell line MG63 were cultured to confluent, and then treated with FD HPRP 20 kGy, FD HPRP 25 kGy, iPRF, and one group non treated as a negative control. Osteocytes were determined based on morphology after hematoxylin staining to see the differentiation process. The data were analyzed using one-way analysis of variance (ANOVA). Results: There was a significant difference in the number of osteocytes between FD HPRP and negative control (P < 0.05). The number of osteocytes FD HPRP 25 was higher than FD HPRP 20. Conclusion: The present results indicate that FD HPRP could support the bone regeneration and used without any preparation like fresh PRP.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"12 1","pages":"91 - 95"},"PeriodicalIF":0.5,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48413491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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