Pub Date : 2023-04-01DOI: 10.4103/denthyp.denthyp_17_23
Shurooq Muhssin, H. Akram
Introduction: We aimed to compare the changes in the two salivary biomarkers, RANKL and RANK, among patients with healthy gingiva on reduced periodontium versus generalized periodontitis stages II and III. Methods: Study subjects were divided into three groups: (1) healthy periodontium (control group) (n = 15), (2) generalized periodontitis stages II and III (n = 30), and (3) healthy gingiva on reduced periodontium (n = 30). Salivary levels of RANKL and RANK were assessed using an enzyme-linked immunosorbent assay. Data analysis was done by the one-way ANOVA and the Tukey post hoc test using R software. Results: There was a statistically significant difference among the three study groups regarding salivary levels of the RANKL (P < 0.001) and RANK (P < 0.001). A Post hoc test showed that the difference between salivary levels of the RANKL (P = 0.50) and RANK (P = 0.86) among periodontitis groups and healthy gingiva in the reduced periodontium group was not statistically significant. Conclusion: High salivary levels of RANKL and RANK in comparison with healthy gingiva are not necessarily associated with the active phase of periodontal disease and progressive bone destruction.
{"title":"Assessment of Salivary Levels of the RANKL and RANK in Patients with Healthy Gingiva on Reduced Periodontium Versus Periodontitis: An Analytical Cross-Sectional Study","authors":"Shurooq Muhssin, H. Akram","doi":"10.4103/denthyp.denthyp_17_23","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_17_23","url":null,"abstract":"Introduction: We aimed to compare the changes in the two salivary biomarkers, RANKL and RANK, among patients with healthy gingiva on reduced periodontium versus generalized periodontitis stages II and III. Methods: Study subjects were divided into three groups: (1) healthy periodontium (control group) (n = 15), (2) generalized periodontitis stages II and III (n = 30), and (3) healthy gingiva on reduced periodontium (n = 30). Salivary levels of RANKL and RANK were assessed using an enzyme-linked immunosorbent assay. Data analysis was done by the one-way ANOVA and the Tukey post hoc test using R software. Results: There was a statistically significant difference among the three study groups regarding salivary levels of the RANKL (P < 0.001) and RANK (P < 0.001). A Post hoc test showed that the difference between salivary levels of the RANKL (P = 0.50) and RANK (P = 0.86) among periodontitis groups and healthy gingiva in the reduced periodontium group was not statistically significant. Conclusion: High salivary levels of RANKL and RANK in comparison with healthy gingiva are not necessarily associated with the active phase of periodontal disease and progressive bone destruction.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"14 1","pages":"49 - 51"},"PeriodicalIF":0.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45093756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01DOI: 10.4103/denthyp.denthyp_44_23
Shahad Obaid, Shahba'a Munther, Marwa Abbas
Introduction: We aimed to assess the possible relationship between dental caries prevalence and oxidative stress markers such as protein carbonyl (PC) and total antioxidant capacity (TAOC) of saliva among type 1 diabetic children. Methods: An analytical cross-sectional study was performed among 45 type 1 diabetic children and compared with 45 healthy control children aged 10 to 12 years old. Dental caries was diagnosed and recorded using the decayed, missing, and filling index (DMFS/dmfs). Unstimulated salivary specimens were collected for evaluation of TAOC and PC using an enzyme-linked immune-sorbent assay (ELISA). A linear regression model and one-way ANOVA test were employed for data analysis using the R 4.3.0. Results: Salivary levels of TAOC and PC, having diabetes, and diabetes status (controlled or uncontrolled) were not statistically significant (P > 0.05) predicators regarding the prevalence of dental caries among type 1diabetic children. Conclusion: The diabetic status had a significant effect on salivary levels of TAOC and PC, but no significant effect on the prevalence of dental caries.
{"title":"Relationship between Salivary Levels of Protein Carbonyl and Total Antioxidant Capacity and Prevalence of Dental Caries among Type 1 Diabetic Children: An Analytical Cross-Sectional Study","authors":"Shahad Obaid, Shahba'a Munther, Marwa Abbas","doi":"10.4103/denthyp.denthyp_44_23","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_44_23","url":null,"abstract":"Introduction: We aimed to assess the possible relationship between dental caries prevalence and oxidative stress markers such as protein carbonyl (PC) and total antioxidant capacity (TAOC) of saliva among type 1 diabetic children. Methods: An analytical cross-sectional study was performed among 45 type 1 diabetic children and compared with 45 healthy control children aged 10 to 12 years old. Dental caries was diagnosed and recorded using the decayed, missing, and filling index (DMFS/dmfs). Unstimulated salivary specimens were collected for evaluation of TAOC and PC using an enzyme-linked immune-sorbent assay (ELISA). A linear regression model and one-way ANOVA test were employed for data analysis using the R 4.3.0. Results: Salivary levels of TAOC and PC, having diabetes, and diabetes status (controlled or uncontrolled) were not statistically significant (P > 0.05) predicators regarding the prevalence of dental caries among type 1diabetic children. Conclusion: The diabetic status had a significant effect on salivary levels of TAOC and PC, but no significant effect on the prevalence of dental caries.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"14 1","pages":"59 - 61"},"PeriodicalIF":0.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49566351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/denthyp.denthyp_35_23
Jafar Kolahi, H. Mirmohammadi, A. Khandan
{"title":"Bibliometric Analysis of Dental Preprints which Published in 2022","authors":"Jafar Kolahi, H. Mirmohammadi, A. Khandan","doi":"10.4103/denthyp.denthyp_35_23","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_35_23","url":null,"abstract":"","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"14 1","pages":"1 - 2"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42300194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/denthyp.denthyp_148_22
Muntadhr Al-Musawi, Omar Ali
Introduction: The study aimed to analyze the level of salivary Interleukin-1 beta (IL-1β) in subjects with healthy periodontium and patients with gingivitis and periodontitis stage I-III. Methods: A total of 90 individuals participated in the research, separated into five groups, clinically healthy (n = 10), gingivitis (n = 20), stage I periodintitis (n = 20), stage II periodontitis (n = 20), and stage III periodontitis (n = 20). Level of salivary IL-1β was assessed using the enzyme-linked immunosorbent assay. Result: A statically significant difference (P < 0.001) found amongst study groups, further multiple group comparison revealed a statistically significant difference (P < 0.05) when comparing the experimental groups with control and when comparing gingivitis with stage II and III groups. Conclusion: Within the limitations of this cross-sectional study, IL-1β can be considered as a potential salivary biomarkers to differentiate between healthy and unhealthy periodontium.
{"title":"Assessment of Salivary Interleukin-1β Levels in Patients with Gingivitis and Periodontitis: An Analytical Cross-Sectional Study","authors":"Muntadhr Al-Musawi, Omar Ali","doi":"10.4103/denthyp.denthyp_148_22","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_148_22","url":null,"abstract":"Introduction: The study aimed to analyze the level of salivary Interleukin-1 beta (IL-1β) in subjects with healthy periodontium and patients with gingivitis and periodontitis stage I-III. Methods: A total of 90 individuals participated in the research, separated into five groups, clinically healthy (n = 10), gingivitis (n = 20), stage I periodintitis (n = 20), stage II periodontitis (n = 20), and stage III periodontitis (n = 20). Level of salivary IL-1β was assessed using the enzyme-linked immunosorbent assay. Result: A statically significant difference (P < 0.001) found amongst study groups, further multiple group comparison revealed a statistically significant difference (P < 0.05) when comparing the experimental groups with control and when comparing gingivitis with stage II and III groups. Conclusion: Within the limitations of this cross-sectional study, IL-1β can be considered as a potential salivary biomarkers to differentiate between healthy and unhealthy periodontium.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"14 1","pages":"3 - 6"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48612776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/denthyp.denthyp_151_22
Duaa Rasan, F. Farhan
Introduction: This study was designed to examine the effects of addition of the combination of polymerized polymethyl methacrylate (PMMA) and zirconia (ZrO2) particles to heat cure PMMA resin on impact strength, surface hardness, and roughness. Methods: The 70% (w/w) of polymerized PMMA powder (particle size: 0.70 µm) was mixed with 30% (w/w) of zirconia powder (ZrO2) (1 µm) to produce PMMA-ZrO2 filler. Ninety acrylic specimens created were divided into three groups containing 0% wt (Control group), 2% wt, and 4% wt, PMMA-ZrO2 filler. Ten specimens were used for impact strength, surface hardness and roughness test, blindly. Data were analyzed via one-way ANOVA and the Tukey post hoc test using R 3.6.3. Results: There was statistically significant difference among study groups regarding surface hardness and roughness (p < 0.001). Yet, nonsignificant difference was found on the subject of impact strength (p = 0.33). Post hoc test showed statistically significant difference for all pairwise comparisons as regards surface hardness and roughness (p < 0.05). Conclusion: The incorporation of PMMA-ZrO2 filler did not improve impact strength (resistance during an unexpected blows or dropping). Yet, increased surface roughness and hardness, concentration-dependently.
{"title":"Effect of addition of polymerized polymethyl methacrylate (PMMA) and zirconia particles on impact strength, surface hardness, and roughness of heat cure PMMA: An in vitro study","authors":"Duaa Rasan, F. Farhan","doi":"10.4103/denthyp.denthyp_151_22","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_151_22","url":null,"abstract":"Introduction: This study was designed to examine the effects of addition of the combination of polymerized polymethyl methacrylate (PMMA) and zirconia (ZrO2) particles to heat cure PMMA resin on impact strength, surface hardness, and roughness. Methods: The 70% (w/w) of polymerized PMMA powder (particle size: 0.70 µm) was mixed with 30% (w/w) of zirconia powder (ZrO2) (1 µm) to produce PMMA-ZrO2 filler. Ninety acrylic specimens created were divided into three groups containing 0% wt (Control group), 2% wt, and 4% wt, PMMA-ZrO2 filler. Ten specimens were used for impact strength, surface hardness and roughness test, blindly. Data were analyzed via one-way ANOVA and the Tukey post hoc test using R 3.6.3. Results: There was statistically significant difference among study groups regarding surface hardness and roughness (p < 0.001). Yet, nonsignificant difference was found on the subject of impact strength (p = 0.33). Post hoc test showed statistically significant difference for all pairwise comparisons as regards surface hardness and roughness (p < 0.05). Conclusion: The incorporation of PMMA-ZrO2 filler did not improve impact strength (resistance during an unexpected blows or dropping). Yet, increased surface roughness and hardness, concentration-dependently.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"14 1","pages":"36 - 38"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44564064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/denthyp.denthyp_126_22
Zahraa Al-Obaidi, H. Jasim
Introduction: We aimed to determine how the various adhesive systems affect the shear bond strength (SBS) to normal and artificially create caries affected dentin (CAD) in permanent teeth. Methods: Forty eight sound premolars had their occlusal enamel ground to create flattened midcoronal dentin. According to the dentin substrate, specimens were allocated into sound and artificially created CAD induction using the pH-cycling technique. Each group was further subdivided according to the adhesive materials: Scotchbond Universal Plus, Scotchbond Universal, and Adper Single Bond 2 adhesives (applied in Etch and Rinse Adhesive Protocol). After that, a composite was put on and shear bond strength (SBS) tests were done. Data analyzed using two-way ANOVA and chi-squared tests. Results: Overall model test of the ANOVA statistics showed that both type of dentin and types of adhesive had a significant effect on the SBS values (P < 0.001). Tuckey post hoc comparisons showed a significant difference for type of dentin (P < 0.001) and types of adhesive (P ≤ 0.005). Mode of failure assessment is non-statistically significant difference (P = 0.41). Conclusion: All adhesives showed a decrease in SBS when used on artificial CAD.
前言:我们的目的是确定不同的粘接剂系统如何影响剪切粘接强度(SBS)对正常恒牙和人工产生龋齿影响的牙本质(CAD)。方法:对48颗正常前磨牙的牙釉质进行磨平,形成扁平的中冠牙本质。根据牙本质基质,采用ph循环技术将标本分配到声音和人工创建的CAD诱导中。根据胶粘剂材料进一步细分为Scotchbond Universal Plus、Scotchbond Universal和Adper Single Bond 2胶粘剂(适用于蚀刻和漂洗胶粘剂协议)。然后,对复合材料进行了剪切粘结强度(SBS)试验。数据分析采用双向方差分析和卡方检验。结果:ANOVA统计的整体模型检验显示,牙本质类型和粘接剂类型对SBS值有显著影响(P < 0.001)。Tuckey事后比较显示牙本质类型(P < 0.001)和粘接剂类型(P≤0.005)有显著差异。失效评估方式差异无统计学意义(P = 0.41)。结论:所有胶粘剂应用于人工CAD时,SBS均有明显下降。
{"title":"Assessment of Shear Bond Strength to Sound and Artificial Caries Affected Dentin Using Different Adhesive Systems: An In Vitro Study","authors":"Zahraa Al-Obaidi, H. Jasim","doi":"10.4103/denthyp.denthyp_126_22","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_126_22","url":null,"abstract":"Introduction: We aimed to determine how the various adhesive systems affect the shear bond strength (SBS) to normal and artificially create caries affected dentin (CAD) in permanent teeth. Methods: Forty eight sound premolars had their occlusal enamel ground to create flattened midcoronal dentin. According to the dentin substrate, specimens were allocated into sound and artificially created CAD induction using the pH-cycling technique. Each group was further subdivided according to the adhesive materials: Scotchbond Universal Plus, Scotchbond Universal, and Adper Single Bond 2 adhesives (applied in Etch and Rinse Adhesive Protocol). After that, a composite was put on and shear bond strength (SBS) tests were done. Data analyzed using two-way ANOVA and chi-squared tests. Results: Overall model test of the ANOVA statistics showed that both type of dentin and types of adhesive had a significant effect on the SBS values (P < 0.001). Tuckey post hoc comparisons showed a significant difference for type of dentin (P < 0.001) and types of adhesive (P ≤ 0.005). Mode of failure assessment is non-statistically significant difference (P = 0.41). Conclusion: All adhesives showed a decrease in SBS when used on artificial CAD.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"14 1","pages":"10 - 12"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47984914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/denthyp.denthyp_140_22
Hussein Ali Hussein, H. Al-Judy
Background: The objective of this research was to explore how the addition of boron nitride (BN) nanoparticles in the concentrations of 1% and 1.5% w/w affect the impact strength and surface roughness of heat-cured poly methyl methacrylate resin (PMMA). Methods: Sixty specimens were made from heat-cured acrylic resin and then divided into control, 1%, and 1.5% w/w BN groups. The impact strength and surface roughness were investigated. One-way ANOVA and Tukey’s post hoc test were used for data analysis. Results: Statistically significant difference is found among the three study groups regarding impact strength (P = 0.011) and surface roughness test (P < 0.001). The post hoc test showed significant differences for all multiple comparisons for the surface roughness test (P < 0.001). Yet, multiple comparisons for the impact strength test revealed only a significant difference between the 1.5% BN and control groups (P = 0.005). Conclusion: The addition of boron BN into PMMA improves impact strength with 1.5% concentration; while adversely increase the surface roughness.
{"title":"Effect of Incorporation of Boron Nitride Nanoparticles on Impact Strength and Surface Roughness of Heat Cure Poly Methyl Methacrylate Resin: An In Vitro Study","authors":"Hussein Ali Hussein, H. Al-Judy","doi":"10.4103/denthyp.denthyp_140_22","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_140_22","url":null,"abstract":"Background: The objective of this research was to explore how the addition of boron nitride (BN) nanoparticles in the concentrations of 1% and 1.5% w/w affect the impact strength and surface roughness of heat-cured poly methyl methacrylate resin (PMMA). Methods: Sixty specimens were made from heat-cured acrylic resin and then divided into control, 1%, and 1.5% w/w BN groups. The impact strength and surface roughness were investigated. One-way ANOVA and Tukey’s post hoc test were used for data analysis. Results: Statistically significant difference is found among the three study groups regarding impact strength (P = 0.011) and surface roughness test (P < 0.001). The post hoc test showed significant differences for all multiple comparisons for the surface roughness test (P < 0.001). Yet, multiple comparisons for the impact strength test revealed only a significant difference between the 1.5% BN and control groups (P = 0.005). Conclusion: The addition of boron BN into PMMA improves impact strength with 1.5% concentration; while adversely increase the surface roughness.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"14 1","pages":"19 - 21"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42932251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/denthyp.denthyp_147_22
Murtatha AL-Anezi, Shahbaa Abduljabar
Introduction: We aimed to evaluate the early and delayed effects of chlorhexidine (CHX) and ozone disinfection on the shear bond strength (SBS) of dentin to glass hybrid restoration. Methods: The occlusal surfaces of 60 extracted premolars were trimmed to obtain a flat dentinal surface and randomly divided into three groups, including distilled water (control), 2% CHX, and ozonized water. Each group was further subjected to a shear bond strength test after 24 hours and 3 months. Results: The overall model test (P < 0.001), disinfectant and time (P < 0.001), and time (P = 0.017) showed statistically significant differences among study groups. Yet, the type of disinfectant revealed a non-significant difference (P = 0.238). Post hoc tests showed SBS significantly decreasing over time in the control group (P < 0.001) while the difference between 24 hours and 3 months for the CHX (P = 0.880) and ozone (P = 0.983) groups was not significant. Conclusion: Within the inherent limitations of in vitro studies, it can be concluded that cavity disinfection with CHX and ozone before glass hybrid restoration had a significant effect on the stability of SBS to dentin over 3 months. The type of disinfectant revealed non-significant difference.
{"title":"Early and Delayed Effect of Cavity Disinfection with Chlorhexidine and Ozone on the Shear Bond Strength of Dentin to Glass Hybrid Restoration: An In Vitro Study","authors":"Murtatha AL-Anezi, Shahbaa Abduljabar","doi":"10.4103/denthyp.denthyp_147_22","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_147_22","url":null,"abstract":"Introduction: We aimed to evaluate the early and delayed effects of chlorhexidine (CHX) and ozone disinfection on the shear bond strength (SBS) of dentin to glass hybrid restoration. Methods: The occlusal surfaces of 60 extracted premolars were trimmed to obtain a flat dentinal surface and randomly divided into three groups, including distilled water (control), 2% CHX, and ozonized water. Each group was further subjected to a shear bond strength test after 24 hours and 3 months. Results: The overall model test (P < 0.001), disinfectant and time (P < 0.001), and time (P = 0.017) showed statistically significant differences among study groups. Yet, the type of disinfectant revealed a non-significant difference (P = 0.238). Post hoc tests showed SBS significantly decreasing over time in the control group (P < 0.001) while the difference between 24 hours and 3 months for the CHX (P = 0.880) and ozone (P = 0.983) groups was not significant. Conclusion: Within the inherent limitations of in vitro studies, it can be concluded that cavity disinfection with CHX and ozone before glass hybrid restoration had a significant effect on the stability of SBS to dentin over 3 months. The type of disinfectant revealed non-significant difference.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"14 1","pages":"16 - 18"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44524451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/denthyp.denthyp_144_22
O. Turki, Z. Jafar
Introduction: We aimed to evaluate the anti-bacterial effect of the Juglans regia dry husk ethanolic extract against Streptococcus mutans and Lactobacillus. Methods: A quantity of 200 g of dry husk was ground into powder and sieved until no large particles were found, then mixed with 1 L of 70% ethanol, yielding 20 g of J. regia paste after ethanol exclusion by vacuum evaporator and lyophilization. The Agar well diffusion method was used to detect the antibacterial activity. Statistical analysis was carried out using Welch’s t-test (unequal variances t-test) via R software. Results: The J. regia dry husk extract showed statistically significant higher bacterial growth inhibition in comparison with prophylaxis pumice paste for both S. mutans and Lactobacillus. Conclusion: Ethanolic dry husk extract has antibacterial activity against both S. mutans and Lactobacillus.
{"title":"Antibacterial Activity of Juglans regia L. Dry Husk Extract against Streptococcus mutans and Lactobacillus: An In Vitro Study","authors":"O. Turki, Z. Jafar","doi":"10.4103/denthyp.denthyp_144_22","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_144_22","url":null,"abstract":"Introduction: We aimed to evaluate the anti-bacterial effect of the Juglans regia dry husk ethanolic extract against Streptococcus mutans and Lactobacillus. Methods: A quantity of 200 g of dry husk was ground into powder and sieved until no large particles were found, then mixed with 1 L of 70% ethanol, yielding 20 g of J. regia paste after ethanol exclusion by vacuum evaporator and lyophilization. The Agar well diffusion method was used to detect the antibacterial activity. Statistical analysis was carried out using Welch’s t-test (unequal variances t-test) via R software. Results: The J. regia dry husk extract showed statistically significant higher bacterial growth inhibition in comparison with prophylaxis pumice paste for both S. mutans and Lactobacillus. Conclusion: Ethanolic dry husk extract has antibacterial activity against both S. mutans and Lactobacillus.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"14 1","pages":"29 - 31"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44912574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/denthyp.denthyp_149_22
Z. Hasan, Noor R. Al-Hasani, M. Mahmood, Ali I Ibrahim
Introduction: We aimed to examine the effect of amoxicillin and azithromycin suspensions on the microhardness of sliver-reinforced glass ionomer and nano-resin modified glass ionomer (GI). Method: Thirty discs (2 mm height x 4 mm diameter) of each type of GI were prepared, which were randomly assigned to amoxicillin, azithromycin, and artificial saliva groups. Microhardness was evaluated by Vickers hardness test before and after three immersion cycles. Results: The overall model (P < 0.001), before/after intervention (P < 0.001), intervention group (type of antibiotic) (P = 0.013), and type of glass ionomer (P < 0.001) showed significant differences among study groups (P < 0.001). Post hoc test showed only non-significant before/after difference for Azithromycin and artificial saliva (control) groups regarding nano resin-modified GI. Conclusion: We found significant microhardness loss for sliver reinforced GI in comparison to nano resin-modified GI after the immersion cycles. Yet, sliver reinforced GI would have higher level of microhardness than nano resin-modified GI after the immersion cycles. Longer time studies are required to assess trend of microhardness loss.
{"title":"Effect of Amoxicillin and Azithromycin Suspensions on Microhardness of Sliver Reinforced and Nano Resin-Modified Glass Ionomers: An In Vitro Study","authors":"Z. Hasan, Noor R. Al-Hasani, M. Mahmood, Ali I Ibrahim","doi":"10.4103/denthyp.denthyp_149_22","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_149_22","url":null,"abstract":"Introduction: We aimed to examine the effect of amoxicillin and azithromycin suspensions on the microhardness of sliver-reinforced glass ionomer and nano-resin modified glass ionomer (GI). Method: Thirty discs (2 mm height x 4 mm diameter) of each type of GI were prepared, which were randomly assigned to amoxicillin, azithromycin, and artificial saliva groups. Microhardness was evaluated by Vickers hardness test before and after three immersion cycles. Results: The overall model (P < 0.001), before/after intervention (P < 0.001), intervention group (type of antibiotic) (P = 0.013), and type of glass ionomer (P < 0.001) showed significant differences among study groups (P < 0.001). Post hoc test showed only non-significant before/after difference for Azithromycin and artificial saliva (control) groups regarding nano resin-modified GI. Conclusion: We found significant microhardness loss for sliver reinforced GI in comparison to nano resin-modified GI after the immersion cycles. Yet, sliver reinforced GI would have higher level of microhardness than nano resin-modified GI after the immersion cycles. Longer time studies are required to assess trend of microhardness loss.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"14 1","pages":"32 - 35"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45047751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}