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Comparative Analysis of Preoperative Ratio Based Markers in Predicting Postoperative Infectious Complications After Gastrectomy. 基于术前比例的指标预测胃切除术后感染并发症的比较分析。
IF 0.6 Q3 Medicine Pub Date : 2022-08-22 DOI: 10.5604/01.3001.0015.9662
Selçuk Gülmez, Aziz Senger, Orhan Uzun, Omer Ozduman, Cem Ofluoglu, İsmail Subasi, Bulent Sen, Mahmud Pence, Ugur Duman, Erdal Polat

Aim: Postoperative infections (POIs) are associated with prolonged postoperative recovery, delayed adjuvant therapy, psychological problems, and poor long-term outcomes. The study aims to cross-compare the ratio-based preoperative parameters to predict POIs in patients with D2 gastrectomy for gastric cancer.

Materials and methods: A retrospective cohort and single-center study evaluated the data of 293 patients who underwent curative gastrectomy between January 2007 and November 2019 in a tertiary hospital in Istanbul. A receiver operating characteristic (ROC) curve was used to assess the ability of laboratory values to predict clinically relevant POIs. The predictive capacity of the neutrophil-lymphocyte ratio (NLR), lymphocyte-monocyte ratio (LMR), platelet-lymphocyte ratio (PLR), and CRP-albumin ratio (CAR) was calculated by the area under the curve. Then, the cutoff points were determined for all 4 indexes.

Results: POIs developed in 77 (26.2%) patients. Patients with POI had higher Charlson comorbidity index (CCI) scores and a longer length of hospital stay. ROC curve analysis revealed that NLR, LMR, and CAR were significantly effective in predicting POI, while PLR was ineffective. LMR was the best ability to predict the POI. According to multivariate analysis, CCI score 3, NLR> 3.8, and LMR 2.34 were independent risk factors influencing the POI.

Conclusion: Preoperative LMR was most predictive for POI. Although CAR predicted the development of the POI, it was not superior to LMR and NLR. PLR did not have any prediction for POI. In addition, increased comorbidity (CCI 3) was an independent risk factor for POI.

目的:术后感染(POIs)与术后恢复时间延长、辅助治疗延迟、心理问题和远期预后不良有关。本研究旨在交叉比较基于比值的术前参数来预测D2胃癌切除术患者的poi。材料和方法:一项回顾性队列和单中心研究评估了2007年1月至2019年11月在伊斯坦布尔一家三级医院接受治愈性胃切除术的293例患者的数据。采用受试者工作特征(ROC)曲线评估实验室值预测临床相关poi的能力。通过曲线下面积计算中性粒细胞-淋巴细胞比率(NLR)、淋巴细胞-单核细胞比率(LMR)、血小板-淋巴细胞比率(PLR)和crp -白蛋白比率(CAR)的预测能力。然后,确定4个指标的截止点。结果:77例(26.2%)患者发生poi。POI患者的Charlson合并症指数(CCI)评分较高,住院时间较长。ROC曲线分析显示,NLR、LMR和CAR对POI的预测有显著效果,而PLR对POI的预测无效。LMR预测POI的能力最好。根据多变量分析,CCI得分为3分,NLR>3.8、2.34是影响POI的独立危险因素。结论:术前LMR对POI的预测效果最好。CAR虽然预测了POI的发展,但并不优于LMR和NLR。PLR对POI没有任何预测。此外,合并症增加(CCI 3)是POI的独立危险因素。
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引用次数: 0
Fecal Occult Blood Test, Is it still worth for Colorectal Cancer Screening? 粪便潜血试验对结直肠癌筛查是否仍有价值?
IF 0.6 Q3 Medicine Pub Date : 2022-08-22 DOI: 10.5604/01.3001.0015.9661
Ahmet Cem Esmer, Şevket Cumhur Yeğen

Introduction: One of the most critical factors determining survival in terms of colorectal cancers is diagnosis and treatment at an early stage. Diagnosis at an early stage is possible with screening programs carried out within preventive health services. In this study, we aimed to compare the results of patients who underwent colonoscopy due to fecal occult blood test (FOBT) positivity with those over 50 years of age who underwent colonoscopy with other complaints and to reveal whether FOBT test is still essential for screening programs.

Methods: This study included patients who underwent colonoscopy between January 2016 and December 2021. Patients were analyzed in two groups according to colonoscopy reasons: group I (FOBT-positive) and group II (other reasons).

Results: A total of 3393 patients were included in the study. The patients were divided into two groups for evaluation. Patients who underwent colonoscopy for FOBT positivity (Group I) and patients over 50 years of age who underwent colonoscopy for other reasons (Group II). When the colonoscopy findings were compared between the groups' inflammatory bowel diseases (p=0,03) were higher in group I, while normal colonoscopy (p=0,03) was found to be more common in group II. Polyps, malignancy, diverticulosis, and perianal diseases seem similar between the groups statistically.

Conclusion: FOBT can still be used in colorectal screening because it is inexpensive, widely available, has more participation due to non-invasiveness, and can be applied outside of clinical settings.

前言:决定结直肠癌患者生存的最关键因素之一是早期的诊断和治疗。通过在预防性保健服务机构内开展筛查方案,可以在早期阶段进行诊断。在这项研究中,我们的目的是比较因粪便隐血检查(FOBT)阳性而进行结肠镜检查的患者与50岁以上因其他疾病进行结肠镜检查的患者的结果,并揭示FOBT检查是否仍然是筛查计划的必要条件。方法:本研究纳入了2016年1月至2021年12月期间接受结肠镜检查的患者。根据结肠镜检查原因将患者分为两组:I组(fobt阳性)和II组(其他原因)。结果:共纳入3393例患者。将患者分为两组进行评估。因FOBT阳性接受结肠镜检查的患者(I组)和年龄超过50岁因其他原因接受结肠镜检查的患者(II组)。炎性肠病(p= 0.03)在ⅰ组较高,而正常结肠镜检查(p= 0.03)在ⅱ组较常见。息肉、恶性肿瘤、憩室病和肛周疾病在组间的统计学上似乎相似。结论:FOBT仍可用于结直肠筛查,因为它价格低廉,可广泛使用,由于无创性而有更多的参与,并且可以在临床环境之外应用。
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引用次数: 0
[Impact of COVID-19 on morbidity, management, and course of acute appendicitisa retrospective cohort study]. [COVID-19对急性阑尾炎发病率、治疗和病程的影响回顾性队列研究]。
IF 0.6 Q3 Medicine Pub Date : 2022-08-22 DOI: 10.5604/01.3001.0015.9659
Łukasz Nawacki

Background: Acute appendicitis is one of the most common causes of abdominal pain requiring surgical intervention. This study aimed to assess the impact of the COVID-19 pandemic on the morbidity, therapeutic management, and course of acute appendicitis.

Methods: This study retrospectively analyzed patients hospitalized at a general surgery department between 1 January 2019 and 19 March 2020 and compared them to patients hospitalized between 20 March 2020 (global pandemic declaration date) and 6 June 2021. Therefore, our analysis encompassed the period 443 days preceding the pandemic and 443 days after the start thereof. Other factors evaluated herein included sex, length of hospital stay, time from symptom onset, type of surgery, laboratory test results, histopathological diagnosis, and polymerase chain reaction test results for SARS-CoV-2 infection.

Results: Statistical analysis was conducted using statistical software IBM SPSS version 27. Significant differences in length of hospital stay, time from symptom onset to hospital admission, number of leukocytes, and type of surgical procedure were observed between groups of patients treated before and after the pandemic.

Conclusion: Acute appendicitis remained one of the most commonly encountered diseases requiring surgical intervention during the COVID-19 pandemic. Overall, significant differences were observed between patients treated before and after COVID-19 had been declared a pandemic.

背景:急性阑尾炎是腹痛最常见的原因之一,需要手术干预。本研究旨在评估COVID-19大流行对急性阑尾炎发病率、治疗管理和病程的影响。方法:本研究回顾性分析了2019年1月1日至2020年3月19日期间在普通外科住院的患者,并将其与2020年3月20日(全球大流行宣布日期)至2021年6月6日期间住院的患者进行了比较。因此,我们的分析涵盖了大流行前443天和大流行开始后443天的时期。本文评估的其他因素包括性别、住院时间、症状出现时间、手术类型、实验室检查结果、组织病理学诊断和SARS-CoV-2感染的聚合酶链反应测试结果。结果:采用IBM SPSS 27版统计软件进行统计分析。在大流行前后接受治疗的患者组之间,在住院时间、从症状出现到住院的时间、白细胞数量和手术类型方面观察到显著差异。结论:急性阑尾炎仍然是新冠肺炎大流行期间最常见的手术干预疾病之一。总体而言,在宣布COVID-19大流行之前和之后接受治疗的患者之间观察到显着差异。
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引用次数: 0
Recto-vaginal fistulas. 直肠阴道瘘管。
IF 0.6 Q3 Medicine Pub Date : 2022-08-22 DOI: 10.5604/01.3001.0015.9658
Tomasz Kościński

Rekomendacje dotycz etiologii i klasyfikacji przetok odbytniczo-pochwowych a przede wszystkim zasad postpowania chirurgicznego. W leczeniu przetok zlokalizowanych w dolnej czci odbytnicy zastosowanie znajduj techniki wycicia kanau przetoki i warstwowego zamykania powstaego ubytku, w tym rwnie z rekonstrukcj aparatu zwieraczowego odbytu. Dla wzmocnienia rekonstruowanych tkanek stosuje si matryc kolagenowo-fibrynow TachosilR. W przypadku wysokich przetok odbytniczo-pochwowych wykonuje si usunicie zmienionego chorobowo odcinka jelita wraz z ujciem przetoki z jednoczasowym lub odroczonym odtworzeniem cigoci przewodu pokarmowego.

关于直肠阴道瘘的病因和分类的建议,最重要的是,手术规则。在治疗位于直肠下部的瘘管时,使用了切开瘘管和分层闭合瘘管的技术,包括重建肛门括约肌。为了增强重建的组织,使用TachosilR胶原纤维蛋白基质。在高位直肠阴道瘘的情况下,将病变的肠段与瘘口一起切除,同时或推迟恢复胃肠道紧密性。
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引用次数: 0
Resection of a large Solid Pseudopapillary Neoplasm of the Pancreas: A multidisciplinary feat and review of literature. 胰腺大实体假乳头状肿瘤的切除:多学科的壮举和文献回顾。
IF 0.6 Q3 Medicine Pub Date : 2022-08-22 DOI: 10.5604/01.3001.0015.9664
Gautam Anand, Deborshi Sharma, Sanjay Meena, Munish Guleria, Anita Nangia

Solid pseudopapillary neoplasm (SPN) is an extremely rare tumor with low malignant potential which is generally located in the tail of the pancreas. The prevalence of SPN has increased with the recent advancement in radiological imaging. CECT abdomen and Endoscopic ultrasound-FNA are excellent modalities in preoperative diagnosis. Surgery is the main treatment modality of choice and a successful R0 resection is curative. We present a case of solid pseudopapillary neoplasm and included a summary of the current literature to provide a reference for the management of this rare clinical entity.

实性假乳头状肿瘤(SPN)是一种非常罕见的肿瘤,恶性潜能低,通常位于胰腺尾部。随着放射成像技术的进步,SPN的发病率也在增加。腹部CECT和内镜超声- fna是术前诊断的良好方式。手术是选择的主要治疗方式,成功的R0切除是治愈的。我们报告了一例实性假乳头状肿瘤,并总结了目前的文献,为这种罕见的临床实体的治疗提供参考。
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引用次数: 0
SCORING SYSTEM FOR PREDICTED SURGICAL-SITE INFECTION IN NEONATES AND PEDIATRIC INTENSIVE CARE UNIT: A PRELIMINARY STUDY. 预测新生儿和儿科重症监护病房手术部位感染的评分系统:初步研究。
IF 0.6 Q3 Medicine Pub Date : 2022-08-22 DOI: 10.5604/01.3001.0015.9660
Leecarlo Lumban Gaol

Background: Surgical-site infections (SSI) account for a large portion of morbidity with the rate of 500,000 cases per year from 27 million surgeries. Some researchers found that factors contributing to surgical wound infections are the number of bacteria contaminants, the bacterias virulence, the micro-environment around the surgical wound, and the immune system of the host.

Objective: To account the risk factors for surgical-site infections in neonatal and pediatric intensive care unit and apply them in a risk index for neonates and pediatrics in critical care unit.

Method: A cohort retrospective study was initiated to investigate risk factors for SSI at Tarakan General Hospital from January 2018 to July 2019. The different factors then analyzed with chi-square test, whereas the multivariate binary logistic regression model was used to examine independent risk factors for SSI.

Result: A total of 179 patients met the inclusion criteria. There were 66 patients in NICU and 113 in PICU. Bivariate analysis showed that SSI was associated with type of ward, operating room temperature, perioperative septicemia, length of stay, and the use of chlorhexidine bath-washing (p<0.05). Multivariate analysis identified three independent parameters correlating with the occurance of SSI: operating room temperature (odds ratio [OR] 12,510; 95% confidence interval [CI] 4,198 37,279; P<0.001); perioperative septicemia (OR 6,424; 95% CI 2,221 18,581; P=0.001); and the use of chlorhexidine bath-washing (OR 35,751; 95% CI 8,627 148,164; P<0.001).

Conclusion: From these three independent paramaters, we recommend a prognostic scoring for SSI in post operative NICUs and PICUs patients that still need another diagnostic, validity and realibility test to improve patients outcome.

背景:手术部位感染(SSI)占发病率的很大一部分,每年2700万例手术中有50万例。一些研究者发现,导致手术创面感染的因素有细菌污染物的数量、细菌的毒力、手术创面周围的微环境和宿主的免疫系统。目的:探讨新生儿和儿科重症监护病房手术部位感染的危险因素,并将其应用于新生儿和儿科重症监护病房的危险指数。方法:对2018年1月至2019年7月在塔拉干总医院进行的SSI危险因素进行队列回顾性研究。采用卡方检验对不同因素进行分析,采用多元二元logistic回归模型对SSI的独立危险因素进行检验。结果:179例患者符合纳入标准。NICU 66例,PICU 113例。双因素分析显示,SSI与病房类型、手术室温度、围手术期败血症、住院时间、洗必泰使用相关(p < 0.05)。多变量分析确定了与SSI发生相关的三个独立参数:手术室温度(优势比[OR] 12,510;95%置信区间[CI] 4,198, 37,279;术中,0.001);围手术期败血症(OR 6424;95% ci 2221 18581;P = 0.001);使用洗必泰洗浴(OR 35,751);95%可信区间8,627,148,164;术中,0.001)。结论:根据这三个独立的参数,我们推荐对术后nicu和picu患者的SSI进行预后评分,这些患者仍需要进行诊断、效度和信度测试,以改善患者的预后。
{"title":"SCORING SYSTEM FOR PREDICTED SURGICAL-SITE INFECTION IN NEONATES AND PEDIATRIC INTENSIVE CARE UNIT: A PRELIMINARY STUDY.","authors":"Leecarlo Lumban Gaol","doi":"10.5604/01.3001.0015.9660","DOIUrl":"https://doi.org/10.5604/01.3001.0015.9660","url":null,"abstract":"<p><strong>Background: </strong>Surgical-site infections (SSI) account for a large portion of morbidity with the rate of 500,000 cases per year from 27 million surgeries. Some researchers found that factors contributing to surgical wound infections are the number of bacteria contaminants, the bacterias virulence, the micro-environment around the surgical wound, and the immune system of the host.</p><p><strong>Objective: </strong>To account the risk factors for surgical-site infections in neonatal and pediatric intensive care unit and apply them in a risk index for neonates and pediatrics in critical care unit.</p><p><strong>Method: </strong>A cohort retrospective study was initiated to investigate risk factors for SSI at Tarakan General Hospital from January 2018 to July 2019. The different factors then analyzed with chi-square test, whereas the multivariate binary logistic regression model was used to examine independent risk factors for SSI.</p><p><strong>Result: </strong>A total of 179 patients met the inclusion criteria. There were 66 patients in NICU and 113 in PICU. Bivariate analysis showed that SSI was associated with type of ward, operating room temperature, perioperative septicemia, length of stay, and the use of chlorhexidine bath-washing (p&lt;0.05). Multivariate analysis identified three independent parameters correlating with the occurance of SSI: operating room temperature (odds ratio [OR] 12,510; 95% confidence interval [CI] 4,198 37,279; P&lt;0.001); perioperative septicemia (OR 6,424; 95% CI 2,221 18,581; P=0.001); and the use of chlorhexidine bath-washing (OR 35,751; 95% CI 8,627 148,164; P&lt;0.001).</p><p><strong>Conclusion: </strong>From these three independent paramaters, we recommend a prognostic scoring for SSI in post operative NICUs and PICUs patients that still need another diagnostic, validity and realibility test to improve patients outcome.</p>","PeriodicalId":43422,"journal":{"name":"Polish Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10769573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A prospective study of head injury patterns in motorcycle riders wearing/not wearing helmets. 戴/不戴头盔摩托车手头部损伤模式的前瞻性研究。
IF 0.6 Q3 Medicine Pub Date : 2022-08-22 DOI: 10.5604/01.3001.0015.9282
Yogesh Takalkar, Kumar Vashist, Vaishnavi Chakravarthy, Pravin Shinde

Introduction: Road traffic accidents (RTA) are a major public health problem and one of the five leading causes of morbidity and mortality around the world. Use of two wheelers are growing rapidly especially inlow to middle income countries leading to an increase in RTA. 27% deaths related to accidents in India are among users of motorized two wheelers.

Aims: To study the pattern of head injuries in motorcycle riders wearing/not wearinghelmets.

Materials and methods: The study is designed as a prospective observational study. Study groups shall be initially categorized based on use of helmets and will be studied in terms of clinical presentation on admission. Basic epidemiological information will be collected in every patient. Case record shall be done in two parts.1) clinical survey 2) radiological survey . Survey is designed as per ATLS guidelines of assessment of trauma patients.

Results: Helmet wearers suffered significantly less head and traumatic brain injuries than the non-helmeted counterparts.

Conclusion: Helmets provide significant protection against the morbidity and mortality of Traumatic brain injury (TBI) as a result of road traffic accidents (RTA).

导言:道路交通事故是一个重大的公共卫生问题,也是全世界发病率和死亡率的五大主要原因之一。两轮车的使用正在迅速增长,特别是中低收入国家,导致区域贸易协定的增加。在印度,27%与事故有关的死亡发生在机动两轮车的使用者中。目的:研究摩托车手戴头盔和不戴头盔的头部损伤规律。材料与方法:本研究为前瞻性观察性研究。研究小组应根据头盔的使用情况进行初步分类,并根据入院时的临床表现进行研究。收集每位患者的流行病学基本信息。病例记录分为两部分:1)临床调查2)放射学调查。调查是根据ATLS创伤患者评估指南设计的。结果:头盔佩戴者的头部和外伤性脑损伤明显少于非头盔佩戴者。结论:头盔对道路交通事故(RTA)所致的创伤性脑损伤(TBI)的发病率和死亡率具有重要的保护作用。
{"title":"A prospective study of head injury patterns in motorcycle riders wearing/not wearing helmets.","authors":"Yogesh Takalkar,&nbsp;Kumar Vashist,&nbsp;Vaishnavi Chakravarthy,&nbsp;Pravin Shinde","doi":"10.5604/01.3001.0015.9282","DOIUrl":"https://doi.org/10.5604/01.3001.0015.9282","url":null,"abstract":"<p><strong>Introduction: </strong>Road traffic accidents (RTA) are a major public health problem and one of the five leading causes of morbidity and mortality around the world. Use of two wheelers are growing rapidly especially inlow to middle income countries leading to an increase in RTA. 27% deaths related to accidents in India are among users of motorized two wheelers.</p><p><strong>Aims: </strong>To study the pattern of head injuries in motorcycle riders wearing/not wearinghelmets.</p><p><strong>Materials and methods: </strong>The study is designed as a prospective observational study. Study groups shall be initially categorized based on use of helmets and will be studied in terms of clinical presentation on admission. Basic epidemiological information will be collected in every patient. Case record shall be done in two parts.1) clinical survey 2) radiological survey . Survey is designed as per ATLS guidelines of assessment of trauma patients.</p><p><strong>Results: </strong>Helmet wearers suffered significantly less head and traumatic brain injuries than the non-helmeted counterparts.</p><p><strong>Conclusion: </strong>Helmets provide significant protection against the morbidity and mortality of Traumatic brain injury (TBI) as a result of road traffic accidents (RTA).</p>","PeriodicalId":43422,"journal":{"name":"Polish Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10747776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the relationship between serum levels of 25-hydroxyvitamin D and prognostic factors in breast cancer. 评价乳腺癌患者血清25-羟基维生素D水平与预后因素的关系。
IF 0.6 Q3 Medicine Pub Date : 2022-08-22 DOI: 10.5604/01.3001.0015.9281
Naeimeh Heiranizadeh, Fatemeh Sadat Alavizadeh, Jamal Jafari Nodooshan, Mahdi Neshan

<b> Introduction:</b> Breast cancer is the most frequent invasive malignancy in women worldwide. There is a modifiable risk factor (such as serum vitamin D level) for this cancer. We decided to conduct this study since the influence of serum vitamin D levels on breast cancer is still controversial. </br></br> <b> Methods and materials:</b> In this analytical cross-sectional study, 103 patients who were diagnosed with breast cancer were included. Patients' demographic, clinical and pathological features were all recorded. After the laboratory provided the serum vitamin D level, it was included in the checklist. Serum vitamin D level was categorized into 3 groups: <10 ng/ml, 1030 ng/ml and >30 ng/ml. The chi-square test was used to assess the relationship between vitamin D levels and clinicopathological features of the patients in SPSS software. The results were considered statistically significant at P-value < 0.05. </br></br> <b> Results:</b> The mean age of the patients was 47.97 8.8 years. The mean serum vitamin D level was 28.72 19.9 ng and it was divided into three groups: 1) deficient (10 ng), which included 20 (19.4%) patients, 2) insufficient (10-30 ng), which included 48 (46.6%) patients, and 3) normal (>30 ng), which included 35 (34%) patients. Low vitamin D level (<320 ng/ml) was mainly detected in premenopausal cases (P-value = 0.001) with poor prognosis high grade of the disease (P-value = 0.001), positive nodal involvement (P-value = 0.025) and positive Ki-67 (P = 0.021). Furthermore, patients with lower serum vitamin D levels interact in fewer outdoor activities (P-value = 0.007), sleep less during the day (P-value = 0.001) and sleep later at night (P-value = 0.009). </br></br> <b>Conclusion:</b> Decreased serum 25(OH) D levels were linked with a higher histological grade of the tumor and lymph node involvement. Low serum 25(OH) D levels were also related to prognostic factors such as high Ki67 expression and the presence of negative hormone receptors (ER and PR). Our data support negative correlations between vitamin D levels and the risk of breast cancer with poor prognostic characteristics, based on observational research.

& lt; b>作品简介:& lt; / b>乳腺癌是世界范围内女性最常见的侵袭性恶性肿瘤。这种癌症有一个可改变的危险因素(如血清维生素D水平)。我们决定进行这项研究,因为血清维生素D水平对乳腺癌的影响仍然存在争议。& lt; / br> & lt; / br>& lt; b>方法和材料:</b>在这项分析性横断面研究中,103名被诊断为乳腺癌的患者被纳入研究。Patients'人口统计学、临床及病理特征均有记录。实验室提供血清维生素D水平后,将其列入检查清单。血清维生素D水平分为10 ng/ml、1030 ng/ml和30 ng/ml 3组。在SPSS软件中采用卡方检验评估维生素D水平与患者临床病理特征的关系。在p值<下认为结果具有统计学意义;0.05. & lt; / br> & lt; / br>& lt; b>结果:& lt; / b>患者平均年龄47.97 8.8岁。血清维生素D水平平均为28.72 19.9 ng,分为3组:1)缺乏(10 ng) 20例(19.4%),2)不足(10 ~ 30 ng) 48例(46.6%),3)正常(30 ng) 35例(34%)。低维生素D水平(<320 ng/ml)主要发生在绝经前患者(P值= 0.001),预后差,疾病分级高(P值= 0.001),淋巴结阳性(P值= 0.025),Ki-67阳性(P = 0.021)。此外,血清维生素D水平较低的患者户外活动较少(p值= 0.007),白天睡眠较少(p值= 0.001),夜间睡眠较晚(p值= 0.009)。& lt; / br> & lt; / br>& lt; b>结论:& lt; / b>血清25(OH) D水平降低与肿瘤和淋巴结受累的较高组织学分级有关。低血清25(OH) D水平也与预后因素有关,如高Ki67表达和负激素受体(ER和PR)的存在。基于观察性研究,我们的数据支持维生素D水平与预后不良的乳腺癌风险之间的负相关。
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引用次数: 0
The Legal nature of guidelines of scientific societies in the light of the Polish legal system. 从波兰法律制度看科学学会导则的法律性质。
IF 0.6 Q3 Medicine Pub Date : 2022-08-12 DOI: 10.5604/01.3001.0015.9579
Maciej Śmietański, Piotr Rączka

Introduction: The paper aims to establish the legal nature of the guidelines in the Polish legal system and the possible formal consequences of introducing such guidelines (litigation, professional responsibility) as well as practical implications concerning the method of treating patients.

Methods: Analysis is clarifying fundamental issues that largely determine the content of the study. The basic assumption is to analyze the legal nature of the prepared guidelines from the point of view of public law, i.e. from the point of view of the relations occurring between the state, as the primary public law entity, and individual, private entities, such as natural persons, legal persons, or organizational units without legal personality, i.e., to be more precise, e.g., the relations between state authorities and persons practicing the medical professionConclusions:Treatment guidelines fall outside the scope of the universally applicable law subsystem. Therefore, they do not constitute sources of universally binding law. 2. Furthermore, the guidelines do not constitute sources of domestic law, as the issuing bodies have no legal authority to issue them and to mould the legal situation of their addressees. 3. In the regulations shaping the rules of practicing the medical profession, both statutory and corporate (the Medical Ethics Code), the guidelines may constitute the basis for adjudicating on the professional (disciplinary) liability of a physician. 4. The guidelines may pose a barrier to the development of medicine, especially in cases where their issuance by ad hoc groups and the lack of updates lead to the consolidation of outdated clinical practice and inhibit the research potential generated from the bottom up.

导言:本文旨在确立波兰法律体系中指导方针的法律性质,以及引入此类指导方针可能产生的正式后果(诉讼,专业责任)以及有关治疗患者方法的实际影响。方法:分析是澄清在很大程度上决定研究内容的基本问题。基本假设是从公法的角度,即从作为主要公法实体的国家与自然人、法人或没有法人资格的组织单位等个人、私人实体之间发生的关系的角度来分析拟定的指导方针的法律性质,更准确地说,例如:结论:治疗准则不属于普遍适用法律分系统的范围。因此,它们不构成具有普遍约束力的法律渊源。2. 此外,这些准则不构成国内法的来源,因为发布准则的机构没有法律权力发布这些准则,也没有权力塑造其收信人的法律状况。3.在形成医疗职业的法定和法人规则的条例(《医疗道德守则》)中,这些准则可构成对医生的专业(纪律)责任作出裁决的基础。4. 这些指南可能对医学发展构成障碍,特别是在由特设小组发布指南和缺乏更新导致过时的临床实践合并并抑制自下而上产生的研究潜力的情况下。
{"title":"The Legal nature of guidelines of scientific societies in the light of the Polish legal system.","authors":"Maciej Śmietański,&nbsp;Piotr Rączka","doi":"10.5604/01.3001.0015.9579","DOIUrl":"https://doi.org/10.5604/01.3001.0015.9579","url":null,"abstract":"<p><strong>Introduction: </strong>The paper aims to establish the legal nature of the guidelines in the Polish legal system and the possible formal consequences of introducing such guidelines (litigation, professional responsibility) as well as practical implications concerning the method of treating patients.</p><p><strong>Methods: </strong>Analysis is clarifying fundamental issues that largely determine the content of the study. The basic assumption is to analyze the legal nature of the prepared guidelines from the point of view of public law, i.e. from the point of view of the relations occurring between the state, as the primary public law entity, and individual, private entities, such as natural persons, legal persons, or organizational units without legal personality, i.e., to be more precise, e.g., the relations between state authorities and persons practicing the medical professionConclusions:Treatment guidelines fall outside the scope of the universally applicable law subsystem. Therefore, they do not constitute sources of universally binding law. 2. Furthermore, the guidelines do not constitute sources of domestic law, as the issuing bodies have no legal authority to issue them and to mould the legal situation of their addressees. 3. In the regulations shaping the rules of practicing the medical profession, both statutory and corporate (the Medical Ethics Code), the guidelines may constitute the basis for adjudicating on the professional (disciplinary) liability of a physician. 4. The guidelines may pose a barrier to the development of medicine, especially in cases where their issuance by ad hoc groups and the lack of updates lead to the consolidation of outdated clinical practice and inhibit the research potential generated from the bottom up.</p>","PeriodicalId":43422,"journal":{"name":"Polish Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10754775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhanced Recovery After Surgery (ERAS) protocol in minimally invasive gynecological surgery: a review of the literature. 微创妇科手术中增强术后恢复(ERAS)方案:文献综述。
IF 0.6 Q3 Medicine Pub Date : 2022-08-12 DOI: 10.5604/01.3001.0015.8687
Stanislav Slavchev, Angel Yordanov

Enhanced Recovery After Surgery (ERAS) is a complex system of procedures that necessitates multidisciplinary patient care during the preoperative, intraoperative, and postoperative phases. Over the last two decades, the ERAS protocol, which was initially described in colorectal surgery, has gradually expanded to other surgical specialties. Gynecological surgery is no exception, whether for benign or malignant conditions. The ERAS program's primary objective is to overcome the pathophysiological processes associated with surgical stress and to facilitate the patient's rapid recovery, while minimizing complications, hospital stays, and costs. The objectives of minimally invasive surgical procedures largely overlap with the objectives of the ERAS program. We analyzed scientific data from studies examining the ERAS system's application in minimally invasive gynecological surgery (MIGS) and present them in this review. The central question is whether the ERAS protocol can provide additional benefits beyond those inherent in minimally invasive surgical procedures.

加强术后恢复(ERAS)是一个复杂的手术系统,需要在术前、术中和术后阶段对患者进行多学科护理。在过去的二十年中,ERAS方案最初是在结直肠手术中描述的,已经逐渐扩展到其他外科专业。妇科手术也不例外,无论是良性的还是恶性的。ERAS项目的主要目标是克服与手术应激相关的病理生理过程,促进患者的快速恢复,同时最大限度地减少并发症、住院时间和费用。微创外科手术的目标在很大程度上与ERAS项目的目标重叠。我们分析了研究ERAS系统在微创妇科手术(MIGS)中应用的科学数据,并将其发表在本文中。核心问题是ERAS方案是否能提供微创外科手术所固有的额外好处。
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引用次数: 0
期刊
Polish Journal of Surgery
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