Pub Date : 2019-09-01DOI: 10.5388/aon.2019.19.3.126
P. Oh, S. Moon
Chemotherapy-related cognitive impairment (CRCI) is one of the most frequently reported side effects of chemotherapy. About 15~70% of cancer patients experience a decline in memory, face problems with attention, and complain of an inability to multitask following chemotherapy. and 17~35% of these cases persist long-term. Even if cognitive decline in cancer patients is mild, it can have a negative impact on their quality of life due to the difficulties it can cause in daily living and work. CRCI primarily presents with abnormalities in pathways connecting the frontal lobe and the subcortical regions, as well as hippocampal damage, leading to the impairment of memory and working memory (immediate memory), attention, and information processing speed. Cognitive function includes receptive functions such as selecting, acquiring, and unifying information, memory and learning, which involves storage and retrieval, mental organization of information and organized thinking, as well as expressive functions such as behavior and communication of information. In terms of anticancer agents that affect CRCI, metabolic inhibitors (e.g., 5-FU, methotrexate), alkylating agents (cyclophosphamide, carmustine), and paclitaxel are reported to be toxic to neural progenitor cells and oligodendrocytes, which form the myelin sheaths in the central nervous system. These anticancer agents are commonly prescribed to patients with stomach or colorectal cancer, which are the most prevalent cancers in Korea. The symptoms and severity of CRCI are affected by various factors, including the cumulative dose of anticancer agents, age, and nutritional status. Interest in CRCI has prompted research in diverse areas, including the treatment agents, as well as the incidence, duration, and extent of cognitive impairment. So far, basic research to manage cognitive decline in cancer patients has focused on investigating the causes of chemotherapy-related cognitive decline. Most studies that have investigated the effects of anticancer treatment itself, including drug dose (standard vs high dose) and hormone therapy, on cognitive function have dealt with breast cancer patients. Thus, further research is required to determine Changes of Cognitive Function and Fatigue following Chemotherapy in Patients with Gastrointestinal Cancer: A Prospective Controlled Study Oh, Pok-Ja ∙ Moon, Sun Mi Department of Nursing, Sahmyook University, Seoul; Surgical Department, Korea Cancer Center Hospital, Seoul, South Korea
化疗相关性认知障碍(CRCI)是化疗最常见的副作用之一。大约15~70%的癌症患者在化疗后会出现记忆力下降、注意力问题和无法同时处理多项任务的症状。其中17~35%的病例长期存在。即使癌症患者的认知能力下降是轻微的，也会给日常生活和工作带来困难，从而对生活质量产生负面影响。CRCI主要表现为连接额叶和皮层下区域的通路异常，以及海马损伤，导致记忆和工作记忆(即时记忆)、注意力和信息处理速度的损害。认知功能包括选择、获取和统一信息、记忆和学习等接受功能，其中包括存储和检索、信息的心理组织和有组织的思维，以及信息的行为和交流等表达功能。在影响CRCI的抗癌药物方面，代谢抑制剂(如5-FU、甲氨蝶呤)、烷基化剂(环磷酰胺、卡莫司汀)和紫杉醇被报道对神经祖细胞和少突胶质细胞有毒性，这些细胞在中枢神经系统中形成髓鞘。这些抗癌药通常用于治疗国内发病率最高的胃癌和大肠癌患者。CRCI的症状和严重程度受多种因素的影响，包括抗癌药物的累积剂量、年龄和营养状况。对CRCI的兴趣促进了不同领域的研究，包括治疗药物，以及认知障碍的发生率、持续时间和程度。到目前为止，管理癌症患者认知能力下降的基础研究主要集中在调查化疗相关认知能力下降的原因。大多数调查抗癌治疗本身影响的研究，包括药物剂量(标准剂量与高剂量)和激素治疗对认知功能的影响，都是针对乳腺癌患者的。因此，需要进一步的研究来确定胃肠道癌症患者化疗后认知功能和疲劳的变化:一项前瞻性对照研究Oh, Pok-Ja∙Moon, Sun Mi, Sahmyook大学护理系，首尔;韩国首尔韩国癌症中心医院外科
{"title":"Changes of Cognitive Function and Fatigue following Chemotherapy in Patients with Gastrointestinal Cancer: A Prospective Controlled Study","authors":"P. Oh, S. Moon","doi":"10.5388/aon.2019.19.3.126","DOIUrl":"https://doi.org/10.5388/aon.2019.19.3.126","url":null,"abstract":"Chemotherapy-related cognitive impairment (CRCI) is one of the most frequently reported side effects of chemotherapy. About 15~70% of cancer patients experience a decline in memory, face problems with attention, and complain of an inability to multitask following chemotherapy. and 17~35% of these cases persist long-term. Even if cognitive decline in cancer patients is mild, it can have a negative impact on their quality of life due to the difficulties it can cause in daily living and work. CRCI primarily presents with abnormalities in pathways connecting the frontal lobe and the subcortical regions, as well as hippocampal damage, leading to the impairment of memory and working memory (immediate memory), attention, and information processing speed. Cognitive function includes receptive functions such as selecting, acquiring, and unifying information, memory and learning, which involves storage and retrieval, mental organization of information and organized thinking, as well as expressive functions such as behavior and communication of information. In terms of anticancer agents that affect CRCI, metabolic inhibitors (e.g., 5-FU, methotrexate), alkylating agents (cyclophosphamide, carmustine), and paclitaxel are reported to be toxic to neural progenitor cells and oligodendrocytes, which form the myelin sheaths in the central nervous system. These anticancer agents are commonly prescribed to patients with stomach or colorectal cancer, which are the most prevalent cancers in Korea. The symptoms and severity of CRCI are affected by various factors, including the cumulative dose of anticancer agents, age, and nutritional status. Interest in CRCI has prompted research in diverse areas, including the treatment agents, as well as the incidence, duration, and extent of cognitive impairment. So far, basic research to manage cognitive decline in cancer patients has focused on investigating the causes of chemotherapy-related cognitive decline. Most studies that have investigated the effects of anticancer treatment itself, including drug dose (standard vs high dose) and hormone therapy, on cognitive function have dealt with breast cancer patients. Thus, further research is required to determine Changes of Cognitive Function and Fatigue following Chemotherapy in Patients with Gastrointestinal Cancer: A Prospective Controlled Study Oh, Pok-Ja ∙ Moon, Sun Mi Department of Nursing, Sahmyook University, Seoul; Surgical Department, Korea Cancer Center Hospital, Seoul, South Korea","PeriodicalId":43724,"journal":{"name":"Asian Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44132471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-01DOI: 10.5388/aon.2019.19.3.159
Yun Ahn, Suk-Jung Han
Purpose: This study was conducted to provide basic data for quality improvement among oncology advanced practice nurses (oncology APNs) through increasing job satisfaction by determining their job satisfaction level and analyzing the influencing factors. Methods: The subjects were 114 certified oncology APNs working at general hospitals in metropolitan areas. Data were collected using a structured questionnaire from August 4 to October 29, 2018. The instruments were the Role Conflict Scale, Self-Efficacy Scale, Professional Self-Concept Scale, and the Level of Job Satisfaction. The data were analyzed using descriptive statistics, t-tests, chi-square tests, ANOVA, Pearson’s correlation coefficients and multiple regression in SPSS version 23.0, IBM. Results: Factors that significantly affected job satisfaction were number of years since being certified as an oncology APN (β=-.20, p=.031), oncology advanced practice (β=.38, p<.001), and professional self-concept (β=.44, p<.001). The explanatory power was 39.4%. Conclusion: These results showed that factors significantly affecting job satisfaction were number of years since being certified as an oncology APN, advanced practice in oncology, and professional self-concept. Job satisfaction was found to be higher when the number of years since being certified as an oncology APN was shorter and professional self-concept was higher.
{"title":"Factors Affecting Job Satisfaction of Oncology Advanced Practice Nurses","authors":"Yun Ahn, Suk-Jung Han","doi":"10.5388/aon.2019.19.3.159","DOIUrl":"https://doi.org/10.5388/aon.2019.19.3.159","url":null,"abstract":"Purpose: This study was conducted to provide basic data for quality improvement among oncology advanced practice nurses (oncology APNs) through increasing job satisfaction by determining their job satisfaction level and analyzing the influencing factors. Methods: The subjects were 114 certified oncology APNs working at general hospitals in metropolitan areas. Data were collected using a structured questionnaire from August 4 to October 29, 2018. The instruments were the Role Conflict Scale, Self-Efficacy Scale, Professional Self-Concept Scale, and the Level of Job Satisfaction. The data were analyzed using descriptive statistics, t-tests, chi-square tests, ANOVA, Pearson’s correlation coefficients and multiple regression in SPSS version 23.0, IBM. Results: Factors that significantly affected job satisfaction were number of years since being certified as an oncology APN (β=-.20, p=.031), oncology advanced practice (β=.38, p<.001), and professional self-concept (β=.44, p<.001). The explanatory power was 39.4%. Conclusion: These results showed that factors significantly affecting job satisfaction were number of years since being certified as an oncology APN, advanced practice in oncology, and professional self-concept. Job satisfaction was found to be higher when the number of years since being certified as an oncology APN was shorter and professional self-concept was higher.","PeriodicalId":43724,"journal":{"name":"Asian Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43394004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-01DOI: 10.5388/aon.2019.19.3.117
S. Y. Lee, Se Na Jung, Sumin Jung, Hyun-Jin Cho, H. Kim
Purpose: The purpose of this study was to identify the self-care agency and quality of life (QOL) among patients with brain tumors after craniotomy. Methods: A sample of 96 patients was recruited from a university hospital in Seoul. Data were collected through a structured questionnaire from August 2017 to December 2018. Data were analyzed with descriptive statistics, t-tests, ANOVA, Pearson correlations and multiple regression analyses with SPSS 24.0, IBM. Results: The mean scores of the 1st and 2nd stages in the selfcare agency increased from 4.75 to 5.15, and in the quality of life rose from 67.94 to 78.60. The score of the second stage was higher than the first in all sub-scales of the self-care agency and the quality. Physical function was the only sub-scale of the self-care agency that affected quality of life in both stages (1st: β=.71, p<.001, 2nd : β=.77, p< .001). Conclusion: Based on the result, to improve QOL with brain tumor after craniotomy, it is important to assess physical function of patients and provide appropriate interventions.
{"title":"Change of the Self-care Agency and Quality of Life after Craniotomy among Patients with Brain tumor according to time","authors":"S. Y. Lee, Se Na Jung, Sumin Jung, Hyun-Jin Cho, H. Kim","doi":"10.5388/aon.2019.19.3.117","DOIUrl":"https://doi.org/10.5388/aon.2019.19.3.117","url":null,"abstract":"Purpose: The purpose of this study was to identify the self-care agency and quality of life (QOL) among patients with brain tumors after craniotomy. Methods: A sample of 96 patients was recruited from a university hospital in Seoul. Data were collected through a structured questionnaire from August 2017 to December 2018. Data were analyzed with descriptive statistics, t-tests, ANOVA, Pearson correlations and multiple regression analyses with SPSS 24.0, IBM. Results: The mean scores of the 1st and 2nd stages in the selfcare agency increased from 4.75 to 5.15, and in the quality of life rose from 67.94 to 78.60. The score of the second stage was higher than the first in all sub-scales of the self-care agency and the quality. Physical function was the only sub-scale of the self-care agency that affected quality of life in both stages (1st: β=.71, p<.001, 2nd : β=.77, p< .001). Conclusion: Based on the result, to improve QOL with brain tumor after craniotomy, it is important to assess physical function of patients and provide appropriate interventions.","PeriodicalId":43724,"journal":{"name":"Asian Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44206533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-01DOI: 10.5388/AON.2019.19.2.106
Jiyoon Jung, J. Park
1. 연구의 필요성 우리나라의 암 발생률은 전국 단위 통계를 산출하기 시작한 1999 년 이후 꾸준히 증가하는 추세로 2014년 암 발생자 수가 217,057명 에 이르러 한해 동안 인구 10만명 당 427.6명이 암 진단을 받았으며 이에 따라 항암제를 투여 받는 환자의 수도 매년 늘어나고 있다. 항암제는 미국 산업안전보건청(National Institute of Occupational Safety & Health, NIOSH)에서 정의한 유해 화학물질로 적은 용량으 로도 발암성(carcinogenicity), 유전독성(genotoxicity), 최기형성(teratogenicity), 생식기능 저하 및 장기 독성을 초래하며(NIOSH, 2004) 피부 접촉, 약물 섭취 등의 직접 노출뿐만 아니라 약물의 조제, 운 반, 준비, 투약, 폐기 및 환자의 체액 또는 배설물 처리 과정에서의 간 접 노출의 위험도 존재한다. 일부 연구에서 항암제 노출로 인한 의
1.研究的必要性我国的癌症发生率自1999年开始以全国为单位进行统计以来一直呈增加趋势，2014年癌症发生人数达到217057人，一年内每10万人中有427.6人被诊断为癌症，因此接受抗癌药治疗的患者数量也在逐年增加。抗癌药是美国国家工业安全与健康研究所（National Institute of Occupational Safety&Health，NIOSH）定义的有害化学物质，用量较少，会导致致癌性（carcinogenicity）、遗传毒性（genotoxicity）、致畸性（teratogenicity）、生殖功能低下和长期毒性（NIOSH，2004），不仅直接接触皮肤、摄取药物等，还会导致药物的配制、运输、准备、投药、废弃以及患者体液或排泄物处理过程中的间接暴露也存在风险。在一些研究中，由于抗癌药物暴露而引起的
{"title":"Factors Influencing Compliance with Safety Guidelines of Anticancer Drugs Among Nurses in General Hospitals","authors":"Jiyoon Jung, J. Park","doi":"10.5388/AON.2019.19.2.106","DOIUrl":"https://doi.org/10.5388/AON.2019.19.2.106","url":null,"abstract":"1. 연구의 필요성 우리나라의 암 발생률은 전국 단위 통계를 산출하기 시작한 1999 년 이후 꾸준히 증가하는 추세로 2014년 암 발생자 수가 217,057명 에 이르러 한해 동안 인구 10만명 당 427.6명이 암 진단을 받았으며 이에 따라 항암제를 투여 받는 환자의 수도 매년 늘어나고 있다. 항암제는 미국 산업안전보건청(National Institute of Occupational Safety & Health, NIOSH)에서 정의한 유해 화학물질로 적은 용량으 로도 발암성(carcinogenicity), 유전독성(genotoxicity), 최기형성(teratogenicity), 생식기능 저하 및 장기 독성을 초래하며(NIOSH, 2004) 피부 접촉, 약물 섭취 등의 직접 노출뿐만 아니라 약물의 조제, 운 반, 준비, 투약, 폐기 및 환자의 체액 또는 배설물 처리 과정에서의 간 접 노출의 위험도 존재한다. 일부 연구에서 항암제 노출로 인한 의","PeriodicalId":43724,"journal":{"name":"Asian Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49096950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-01DOI: 10.5388/AON.2019.19.2.55
Jung Ee Kim, H. So
Purpose: The purpose of this study was to explore the experience of hope of terminal cancer patients in Korea. Methods: Seven participants receiving hospice care were interviewed about hope experiences based on Parse’s research methodology. Results: Practical propositions derived from the structure of the hope experience were: Terminal cancer patients are beings newly recognizing the value of their lives by maintaining their hopes while they are experiencing powerlessness due to feelings of loss and distress. Ways of truly being with them are accepting their experience of distress, understanding the existence of paradoxical relationships, active symptom management, and finding hope in the current situation. Through these processes, the patients restructure their remaining lives for peaceful death by changing their perceptions about death. This structure can be interpreted as ‘the hope experience of terminal cancer patients is a process of changing the value of life, overcoming fear of death, enhancing meaning, and transcending.’ Conclusion: The concept of ‘true presence’ applied in this study was proved to be an effective nursing practice improving quality of life of the patients. Parse’s Human Becoming Methodology may be applied to terminal cancer patients in the future.
{"title":"Experience of Hope in Terminal Cancer Patients: Applying Parse' s Human Becoming Methodology","authors":"Jung Ee Kim, H. So","doi":"10.5388/AON.2019.19.2.55","DOIUrl":"https://doi.org/10.5388/AON.2019.19.2.55","url":null,"abstract":"Purpose: The purpose of this study was to explore the experience of hope of terminal cancer patients in Korea. Methods: Seven participants receiving hospice care were interviewed about hope experiences based on Parse’s research methodology. Results: Practical propositions derived from the structure of the hope experience were: Terminal cancer patients are beings newly recognizing the value of their lives by maintaining their hopes while they are experiencing powerlessness due to feelings of loss and distress. Ways of truly being with them are accepting their experience of distress, understanding the existence of paradoxical relationships, active symptom management, and finding hope in the current situation. Through these processes, the patients restructure their remaining lives for peaceful death by changing their perceptions about death. This structure can be interpreted as ‘the hope experience of terminal cancer patients is a process of changing the value of life, overcoming fear of death, enhancing meaning, and transcending.’ Conclusion: The concept of ‘true presence’ applied in this study was proved to be an effective nursing practice improving quality of life of the patients. Parse’s Human Becoming Methodology may be applied to terminal cancer patients in the future.","PeriodicalId":43724,"journal":{"name":"Asian Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45211104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-01DOI: 10.5388/AON.2019.19.2.90
Jin-Hee Park, Y. Jung, J. Kim, S. Bae, Yujung Jo
Purpose: The aim of this study was to evaluate the severity of menopausal symptoms and their impact on the quality of life (QOL) in breast cancer patients with chemotherapy-induced amenorrhea. Methods: A cross-sectional survey design was used. Participants were 112 breast cancer patients with chemotherapy-induced amenorrhea. They completed the Menopause Rating Scale (MRS) and the Functional Assessment of Cancer Therapy-General (FACT-G). Data were analyzed using descriptive statistics, independent ttests, one-way ANOVA, Pearson’s correlation coefficients, and multiple regression with SPSS/WIN 23.0. Results: The prevalence of symptoms among the participants were as follows: sleep problems, 88.4%; physical and mental exhaustion, 80.4%; joint and muscular discomfort, 76.8%; and depression, 70.5%. Menopausal symptoms had a significant negative association with QOL. The results of the regression analysis showed that psychological and urogenital symptoms were statistically significant in explaining patients’ QOL and accounted for 70% of the total variance. Conclusion: Menopausal symptoms appear to be a significant problem for premenopausal breast cancer patients. Assessment and control of menopausal symptoms played a large role in maintaining the quality of life in breast cancer patients.
{"title":"Menopausal Symptoms and Quality of Life Among Breast Cancer Patients with Chemotherapy-induced Amenorrhea","authors":"Jin-Hee Park, Y. Jung, J. Kim, S. Bae, Yujung Jo","doi":"10.5388/AON.2019.19.2.90","DOIUrl":"https://doi.org/10.5388/AON.2019.19.2.90","url":null,"abstract":"Purpose: The aim of this study was to evaluate the severity of menopausal symptoms and their impact on the quality of life (QOL) in breast cancer patients with chemotherapy-induced amenorrhea. Methods: A cross-sectional survey design was used. Participants were 112 breast cancer patients with chemotherapy-induced amenorrhea. They completed the Menopause Rating Scale (MRS) and the Functional Assessment of Cancer Therapy-General (FACT-G). Data were analyzed using descriptive statistics, independent ttests, one-way ANOVA, Pearson’s correlation coefficients, and multiple regression with SPSS/WIN 23.0. Results: The prevalence of symptoms among the participants were as follows: sleep problems, 88.4%; physical and mental exhaustion, 80.4%; joint and muscular discomfort, 76.8%; and depression, 70.5%. Menopausal symptoms had a significant negative association with QOL. The results of the regression analysis showed that psychological and urogenital symptoms were statistically significant in explaining patients’ QOL and accounted for 70% of the total variance. Conclusion: Menopausal symptoms appear to be a significant problem for premenopausal breast cancer patients. Assessment and control of menopausal symptoms played a large role in maintaining the quality of life in breast cancer patients.","PeriodicalId":43724,"journal":{"name":"Asian Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43227626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-01DOI: 10.5388/AON.2019.19.2.71
Y. J. Yoon, Jeong-Sook Park
치료와 새로운 치료법의 개발 등으로 암환자의 생존율이 증가하였 으나, 치료 과정에서 생기는 부작용으로 인해 암환자의 질병 경험 과 개인의 안녕에 부정적인 영향을 미치는 경우도 많아졌다. 항암 화학요법은 대표적인 암 치료방법 중 하나로서, 다양한 암종의 치료 를 위해 광범위하게 사용되고 있으나, 항암화학요법에 따르는 오심, 구토, 탈모, 점막염, 말초신경병증, 피부 및 손톱 변색, 감염, 빈혈, 출 혈 등의 다양한 부작용으로 인해 고통 받는 경우도 많아지고 있다. 이러한 부작용 중 말초신경병증은 말초신경계에 있는 감각신경, 운동신경, 자율신경 등에 염증, 손상 및 퇴화를 초래하는 것으로, 주로 손과 발의 감각 증상이 많이 나타난다. 통증, 무감각 또는 따끔 거림이 전형적으로 양말과 장갑 양상(stocking-glove)으로 나타나거 나, 근육 허약감, 균형 장애와 같은 운동증상, 뇌신경 결핍 또는 자 율신경계 증상도 나타난다. 말초신경병증은 급성으로 나타나거나
{"title":"Factors Influencing Peripheral Neuropathy of Cancer Patients Undergoing Chemotherapy","authors":"Y. J. Yoon, Jeong-Sook Park","doi":"10.5388/AON.2019.19.2.71","DOIUrl":"https://doi.org/10.5388/AON.2019.19.2.71","url":null,"abstract":"치료와 새로운 치료법의 개발 등으로 암환자의 생존율이 증가하였 으나, 치료 과정에서 생기는 부작용으로 인해 암환자의 질병 경험 과 개인의 안녕에 부정적인 영향을 미치는 경우도 많아졌다. 항암 화학요법은 대표적인 암 치료방법 중 하나로서, 다양한 암종의 치료 를 위해 광범위하게 사용되고 있으나, 항암화학요법에 따르는 오심, 구토, 탈모, 점막염, 말초신경병증, 피부 및 손톱 변색, 감염, 빈혈, 출 혈 등의 다양한 부작용으로 인해 고통 받는 경우도 많아지고 있다. 이러한 부작용 중 말초신경병증은 말초신경계에 있는 감각신경, 운동신경, 자율신경 등에 염증, 손상 및 퇴화를 초래하는 것으로, 주로 손과 발의 감각 증상이 많이 나타난다. 통증, 무감각 또는 따끔 거림이 전형적으로 양말과 장갑 양상(stocking-glove)으로 나타나거 나, 근육 허약감, 균형 장애와 같은 운동증상, 뇌신경 결핍 또는 자 율신경계 증상도 나타난다. 말초신경병증은 급성으로 나타나거나","PeriodicalId":43724,"journal":{"name":"Asian Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42863412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-01DOI: 10.5388/AON.2019.19.2.81
P. Oh, Eunjoo Choi, Jin Lee
작용을 초래한다. 그 중 항암화학요법 관련 말초신경병증(chemotherapy induced peripheral neuropathy [CIPN])은 신경독성 항암제 (platinum계, taxane계, vinca-alkaloid계, thalidomide, bortezomib)의 축적으로 말초신경손상이 초래된 것을 말한다. 이들 항암제는 대 장암, 위암, 유방암, 혈액암 등 환자에게 흔히 처방되고 있으며, 약 물투여 1달 후 암 환자의 68.0%, 3개월 후 약 60.0%가 CIPN을 경험하 며 암 환자의 30.0%는 6개월 이상 수년간 CIPN을 경험한다. 신경독 성 항암제 중 oxaliplatin의 경우 CIPN은 항암제 투여 1시간 내에 발 생하여 몇 일내로 사라지는 급성과 14일 내에 사라지지 않고 이후까 지 지속되는 만성 신경손상을 초래하는 것으로 보고된다. Park 등 은 암 생존자의 40.0%는 만성적으로 지속되는 CIPN을 경험하거나 심한 경우 불가역적인 후유증을 갖는 것으로 보고하였다. 따라서
{"title":"The Experience of Chemotherapy-induced Peripheral Neuropathy in People with Cancer","authors":"P. Oh, Eunjoo Choi, Jin Lee","doi":"10.5388/AON.2019.19.2.81","DOIUrl":"https://doi.org/10.5388/AON.2019.19.2.81","url":null,"abstract":"작용을 초래한다. 그 중 항암화학요법 관련 말초신경병증(chemotherapy induced peripheral neuropathy [CIPN])은 신경독성 항암제 (platinum계, taxane계, vinca-alkaloid계, thalidomide, bortezomib)의 축적으로 말초신경손상이 초래된 것을 말한다. 이들 항암제는 대 장암, 위암, 유방암, 혈액암 등 환자에게 흔히 처방되고 있으며, 약 물투여 1달 후 암 환자의 68.0%, 3개월 후 약 60.0%가 CIPN을 경험하 며 암 환자의 30.0%는 6개월 이상 수년간 CIPN을 경험한다. 신경독 성 항암제 중 oxaliplatin의 경우 CIPN은 항암제 투여 1시간 내에 발 생하여 몇 일내로 사라지는 급성과 14일 내에 사라지지 않고 이후까 지 지속되는 만성 신경손상을 초래하는 것으로 보고된다. Park 등 은 암 생존자의 40.0%는 만성적으로 지속되는 CIPN을 경험하거나 심한 경우 불가역적인 후유증을 갖는 것으로 보고하였다. 따라서","PeriodicalId":43724,"journal":{"name":"Asian Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47977513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-01DOI: 10.5388/AON.2019.19.2.98
J. Byeon, Mi Kyung Lee, J. Chung, Samuel Yoo, J. Jeon
암 발생률의 증가와 더불어 조기 검진을 통한 빠른 치료적 접근 및 치료 기술의 발달로 암 생존자 수는 증가하는 추세이다. 그 중 대 장암은 우리나라 주요 암 발생 중 2위를 차지하고 있으며, 5년 상대 생존율은 1990년대 50%대에서 현재 76.3%로 증가하여 대장암 생존 자가 점차 늘어나고 있다. 암 생존자들은 일반인에 비해 신체적, 정신적 삶의 질이 낮은 것 으로 보고되고 있어 치료 후 그들의 전반적인 삶에 관심을 가져야 할 필요가 있다. 대장암 생존자의 경우에는 수술, 항암화학요법, 방 사선치료를 겪으며 옥살리플라틴 관련 말초신경병증(Oxaliplatininduced Peripheral Neuropathy), 배변장애(Bowel Dysfunction), 방사 선 후 골반 불완전 골절(Pelvic Insufficiency Fractures after Radiation), 비뇨 생식기 장애(Urogenital Dysfunction) 등의 부작용을 경험하게 된다. Baker 등 의 연구에서는 대장암 진단 후 1년이 경과한 환자 들의 주요 어려움으로 재발에 대한 두려움(67.9%), 피로(60.7%) 및 미 래에 대한 불안(58.9%), 신체적 변화에 대한 불편함(35.1%)이 보고되 었다. 이렇듯 치료 종료 후 대장암 생존자들은 신체적, 정신적 다양
随着癌症发生率的增加，通过早期检查的快速治疗接近及治疗技术的发展，癌症生存者人数呈增加趋势。其中，大肠炎在韩国主要癌症发生中占第2位，相对5年生存率从20世纪90年代的50%增加到现在的76.3%，大肠癌生存者正在逐渐增加。据报告，癌症幸存者的身体、精神生活质量比普通人低，因此，治疗后有必要关注他们的整体生活。大肠癌幸存者的情况是，经过手术、化疗和放线治疗后，与奥苏利铂相关的末梢神经病症(oxaliplatinduced Peripheral Neuropathy)、排便障碍(Bowel Dysfunction)、放射后骨盆不完全骨折(Pelvic Insufficiency Fractures after Radiation)、会出现泌尿器官障碍(Urogenital Dysfunction)等副作用。在Baker等人的研究中，对大肠癌诊断1年后的患者的主要困难有:对复发的恐惧(67.9%)、疲劳(60.7%)、对未来的不安(58.9%)、对身体变化的不便(35.1%)。治疗结束后大肠癌的幸存者身体和精神上都有差异
{"title":"Exercise Participation Experiences of Colorectal Cancer Survivors","authors":"J. Byeon, Mi Kyung Lee, J. Chung, Samuel Yoo, J. Jeon","doi":"10.5388/AON.2019.19.2.98","DOIUrl":"https://doi.org/10.5388/AON.2019.19.2.98","url":null,"abstract":"암 발생률의 증가와 더불어 조기 검진을 통한 빠른 치료적 접근 및 치료 기술의 발달로 암 생존자 수는 증가하는 추세이다. 그 중 대 장암은 우리나라 주요 암 발생 중 2위를 차지하고 있으며, 5년 상대 생존율은 1990년대 50%대에서 현재 76.3%로 증가하여 대장암 생존 자가 점차 늘어나고 있다. 암 생존자들은 일반인에 비해 신체적, 정신적 삶의 질이 낮은 것 으로 보고되고 있어 치료 후 그들의 전반적인 삶에 관심을 가져야 할 필요가 있다. 대장암 생존자의 경우에는 수술, 항암화학요법, 방 사선치료를 겪으며 옥살리플라틴 관련 말초신경병증(Oxaliplatininduced Peripheral Neuropathy), 배변장애(Bowel Dysfunction), 방사 선 후 골반 불완전 골절(Pelvic Insufficiency Fractures after Radiation), 비뇨 생식기 장애(Urogenital Dysfunction) 등의 부작용을 경험하게 된다. Baker 등 의 연구에서는 대장암 진단 후 1년이 경과한 환자 들의 주요 어려움으로 재발에 대한 두려움(67.9%), 피로(60.7%) 및 미 래에 대한 불안(58.9%), 신체적 변화에 대한 불편함(35.1%)이 보고되 었다. 이렇듯 치료 종료 후 대장암 생존자들은 신체적, 정신적 다양","PeriodicalId":43724,"journal":{"name":"Asian Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5388/AON.2019.19.2.98","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48055610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-03-01DOI: 10.5388/AON.2019.19.1.47
S. Shim, Jeong Hye Kim
Purpose: The purpose of this study was to investigate the resilience and quality of life (QoL) of patients with non-Hodgkin lymphoma (NHL) and the factors influencing QoL. Methods: A sample of 85 outpatients who had been diagnosed with NHL were included in a descriptive study. The instruments used were the Connor-Davidson Resilience Scale and Functional Assessment of Cancer TherapyLymphoma (FACT-Lym) version 4. Results: The mean resilience score of the patients was 73.11±15.81 out of 100. The total mean QoL score was 130.23±20.70 out of 168, the highest category was physical well-being with a mean item score of 21.80±5.03, the lowest was emotional well-being with a mean item score of 19.28±3.95. Resilience and QoL were positively correlated (r=.65, p<.001). Regression analysis revealed that the QoL of the patients was explained by resilience, gender, and Eastern Cooperative Oncology Group performance status. These variables explained 53% of the variance of QoL. Conclusion: The results of this study confirmed the importance of resilience for QoL among patients with NHL and the relevant factors that affect QoL. This can be used as a basis for nursing interventions for NHL patients.
{"title":"The Influence of Resilience on the Quality of Life of Patients with non-Hodgkin Lymphoma","authors":"S. Shim, Jeong Hye Kim","doi":"10.5388/AON.2019.19.1.47","DOIUrl":"https://doi.org/10.5388/AON.2019.19.1.47","url":null,"abstract":"Purpose: The purpose of this study was to investigate the resilience and quality of life (QoL) of patients with non-Hodgkin lymphoma (NHL) and the factors influencing QoL. Methods: A sample of 85 outpatients who had been diagnosed with NHL were included in a descriptive study. The instruments used were the Connor-Davidson Resilience Scale and Functional Assessment of Cancer TherapyLymphoma (FACT-Lym) version 4. Results: The mean resilience score of the patients was 73.11±15.81 out of 100. The total mean QoL score was 130.23±20.70 out of 168, the highest category was physical well-being with a mean item score of 21.80±5.03, the lowest was emotional well-being with a mean item score of 19.28±3.95. Resilience and QoL were positively correlated (r=.65, p<.001). Regression analysis revealed that the QoL of the patients was explained by resilience, gender, and Eastern Cooperative Oncology Group performance status. These variables explained 53% of the variance of QoL. Conclusion: The results of this study confirmed the importance of resilience for QoL among patients with NHL and the relevant factors that affect QoL. This can be used as a basis for nursing interventions for NHL patients.","PeriodicalId":43724,"journal":{"name":"Asian Oncology Nursing","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43622857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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