Pub Date : 2019-09-03DOI: 10.12680/balneo.2019.265
A. Ciubean, Laszlo Irsay, R. Ungur, V. Ciortea, Ileana Monica Borda, B. G. Dogaru, A. Trifa, A. Buzoianu
Objectives: This study aimed to assess the relationship between bone mineral density, fragility fractures, fracture risk and polymorphisms of two osteoporosis-candidate genes (GGPS1 and RANKL) in Romanian women with postmenopausal osteoporosis. Methods: An analytical, prospective, transversal, observational, case-control study on 364 postmenopausal women, of which 228 were previously diagnosed with osteoporosis, was carried out between June 2016 and August 2017 in Cluj Napoca, Romania. Clinical data and blood samples were collected from all study participants. Polymorphisms in GGPS1 and RANKL genes were genotyped using TaqMan SNP Genotyping assays, run on a QuantStudio 3 real-time PCR machine. Results: The CT genotype in GGPS1 rs10925503 was associated with significant lower bone mineral density values at lumbar spine and femoral neck sites and a higher fracture risk compared to controls. No significant association was found between genotypes of RANKL rs2277439 with bone mineral density or fracture risk compared to the healthy controls. Conclusions: Our study showed a strong association between low bone mineral density and genotype CT of GGPS1 rs10925503 polymorphisms. No association was found for RANKL rs2277439 polymorphism.
{"title":"Association between polymorphisms in GGPS1 and RANKL genes and postmenopausal osteoporosis in Romanian women","authors":"A. Ciubean, Laszlo Irsay, R. Ungur, V. Ciortea, Ileana Monica Borda, B. G. Dogaru, A. Trifa, A. Buzoianu","doi":"10.12680/balneo.2019.265","DOIUrl":"https://doi.org/10.12680/balneo.2019.265","url":null,"abstract":"Objectives: This study aimed to assess the relationship between bone mineral density, fragility fractures, fracture risk and polymorphisms of two osteoporosis-candidate genes (GGPS1 and RANKL) in Romanian women with postmenopausal osteoporosis. \u0000 Methods: An analytical, prospective, transversal, observational, case-control study on 364 postmenopausal women, of which 228 were previously diagnosed with osteoporosis, was carried out between June 2016 and August 2017 in Cluj Napoca, Romania. Clinical data and blood samples were collected from all study participants. Polymorphisms in GGPS1 and RANKL genes were genotyped using TaqMan SNP Genotyping assays, run on a QuantStudio 3 real-time PCR machine.\u0000Results: The CT genotype in GGPS1 rs10925503 was associated with significant lower bone mineral density values at lumbar spine and femoral neck sites and a higher fracture risk compared to controls. No significant association was found between genotypes of RANKL rs2277439 with bone mineral density or fracture risk compared to the healthy controls. \u0000 Conclusions: Our study showed a strong association between low bone mineral density and genotype CT of GGPS1 rs10925503 polymorphisms. No association was found for RANKL rs2277439 polymorphism.","PeriodicalId":43815,"journal":{"name":"Balneo Research Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43579314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-03DOI: 10.12680/balneo.2019.263
I. Stanescu, A. Bulboacă, G. Dogaru, G. Gusetu, Dana Marieta Fodor
Disability as a stroke consequence is reported by 3% males and 2% females in general population. Motor deficits are common in stroke patients, but their complete recovery is seen only in a minority of cases. Assessment of motor deficits uses clinical methods, especially standardized scales, but also electrophysiological and imagistic methods. The motor recovery is a continuous process, maximal in the first month after stroke, decreasing gradually over the first 6 months. Most powerful predictors for motor recovery are clinical parameters: severity of motor deficit, onset of first voluntary movements after stroke in the first 48-72 hours, a continuous improvement in motor function during the first 8 weeks, a good postural control during the first month, young age, male sex, left hemispheric stroke and absence of other neurological impairments are strong positive predictors. Presence of motor-evoked potentials in paretic muscles and imagistic parameters as location, stroke volume and motor pathways integrity are paraclinical predictors for recovery. There are no specific biomarker which is efficient in predicting recovery. In patients with poor chances for recovery according to actual predictors, the development of more precise algorithms to assess functional outcome is needed, in order to support the choice of appropriate methods and intensity of rehabilitation treatment. Key words: ischemic stroke rehabilitation, functional assessment, motor improvement, recovery predictors, prognostic factors,
{"title":"Predictors for early motor improvement in patients with ischemic stroke","authors":"I. Stanescu, A. Bulboacă, G. Dogaru, G. Gusetu, Dana Marieta Fodor","doi":"10.12680/balneo.2019.263","DOIUrl":"https://doi.org/10.12680/balneo.2019.263","url":null,"abstract":"Disability as a stroke consequence is reported by 3% males and 2% females in general population. Motor deficits are common in stroke patients, but their complete recovery is seen only in a minority of cases. Assessment of motor deficits uses clinical methods, especially standardized scales, but also electrophysiological and imagistic methods. The motor recovery is a continuous process, maximal in the first month after stroke, decreasing gradually over the first 6 months. Most powerful predictors for motor recovery are clinical parameters: severity of motor deficit, onset of first voluntary movements after stroke in the first 48-72 hours, a continuous improvement in motor function during the first 8 weeks, a good postural control during the first month, young age, male sex, left hemispheric stroke and absence of other neurological impairments are strong positive predictors. Presence of motor-evoked potentials in paretic muscles and imagistic parameters as location, stroke volume and motor pathways integrity are paraclinical predictors for recovery. There are no specific biomarker which is efficient in predicting recovery. In patients with poor chances for recovery according to actual predictors, the development of more precise algorithms to assess functional outcome is needed, in order to support the choice of appropriate methods and intensity of rehabilitation treatment.\u0000Key words: ischemic stroke rehabilitation, functional assessment, motor improvement, recovery predictors, prognostic factors,","PeriodicalId":43815,"journal":{"name":"Balneo Research Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41583618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-03DOI: 10.12680/balneo.2019.273
S. Gushcha, A. Plakida, B. Nasibullin, V. Volyanska, Ivan Savitskyі, Tatyana Gladkіy
In the modern world, a lack of magnesium in the body is one of the most common deficient conditions in humans. Low levels of magnesium have been associated with a number of chronic diseases. This work is devoted to the study of the effect of the use of the balneological means "Magnesium oil" for the correction of the manifestations of experimentally induced magnesium deficiency. The experiment was conducted on 50 white female rats of the Wistar auto-breeding line which were divided into 3 equal groups: (1) control, (2) model of magnesium deficiency, (3) received "Magnesium oil". As a result of modeling the state of magnesium deficiency, significant changes are observed in the central nervous system, vegetative nervous system, and kidneys of animals. The use of balneological means "Magnesium oil" can significantly reduce the negative manifestations of magnesium deficiency.
{"title":"Correction of magnesium deficiency in the body with balneological means: experimental studies","authors":"S. Gushcha, A. Plakida, B. Nasibullin, V. Volyanska, Ivan Savitskyі, Tatyana Gladkіy","doi":"10.12680/balneo.2019.273","DOIUrl":"https://doi.org/10.12680/balneo.2019.273","url":null,"abstract":"In the modern world, a lack of magnesium in the body is one of the most common deficient conditions in humans. Low levels of magnesium have been associated with a number of chronic diseases. This work is devoted to the study of the effect of the use of the balneological means \"Magnesium oil\" for the correction of the manifestations of experimentally induced magnesium deficiency. The experiment was conducted on 50 white female rats of the Wistar auto-breeding line which were divided into 3 equal groups: (1) control, (2) model of magnesium deficiency, (3) received \"Magnesium oil\". As a result of modeling the state of magnesium deficiency, significant changes are observed in the central nervous system, vegetative nervous system, and kidneys of animals. The use of balneological means \"Magnesium oil\" can significantly reduce the negative manifestations of magnesium deficiency.","PeriodicalId":43815,"journal":{"name":"Balneo Research Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47962099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-03DOI: 10.12680/balneo.2019.267
Corneliu Angelo Bulboaca, M. Blidaru, D. Feștilă, Paul-Mihai Boarescu, I. Stanescu
The neurological diagnosis, can be, in some situations, a challenging one. Clinical presentation for neurological disease, which has no imagistic diagnosis criteria, can develop during several month or years. Therefore, the first evaluation of the patient with neurological symptoms is not always conclusive. Pallidopyramidal syndrome and hereditary spastic paraplegia (HSP) can present common features and diagnostic approach has to be careful. genetic assessment is the gold diagnosis method in some cases. Therapeutic strategies, following a correct diagnosis has to be addressed to improvement the patient's quality of life by rehabilitation methods and medication targeting the pathophysiological processes involvement. The aim of this paper is to discuss the clinical evolution and the diagnosis strategies in hereditary spastic paraplegia.
{"title":"Pallidopyramidal Syndrome and Hereditary Spastic Paraplegia common features and diagnostic approach and therapeutic considerations","authors":"Corneliu Angelo Bulboaca, M. Blidaru, D. Feștilă, Paul-Mihai Boarescu, I. Stanescu","doi":"10.12680/balneo.2019.267","DOIUrl":"https://doi.org/10.12680/balneo.2019.267","url":null,"abstract":"The neurological diagnosis, can be, in some situations, a challenging one. Clinical presentation for neurological disease, which has no imagistic diagnosis criteria, can develop during several month or years. Therefore, the first evaluation of the patient with neurological symptoms is not always conclusive. Pallidopyramidal syndrome and hereditary spastic paraplegia (HSP) can present common features and diagnostic approach has to be careful. genetic assessment is the gold diagnosis method in some cases. Therapeutic strategies, following a correct diagnosis has to be addressed to improvement the patient's quality of life by rehabilitation methods and medication targeting the pathophysiological processes involvement. The aim of this paper is to discuss the clinical evolution and the diagnosis strategies in hereditary spastic paraplegia.","PeriodicalId":43815,"journal":{"name":"Balneo Research Journal","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41355970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-03DOI: 10.12680/balneo.2019.276
Scientific Program Oral Presentations Authors Title Abstract CONSTANTIN MUNTEANU, Mihail HOTETEU, Diana MUNTEANU, Gabriela DOGARU - 12 minutes PERSPECTIVES OF BALNEOLOGY - INTERNATIONAL DATA INPUTS, NATIONAL OUTPUTS Link L1 UMBERTO SOLIMENE - 14 minutes CLIMATE AND HEALTH: A NEW CHALLENGE FOR AN OLD SCIENCE Link L2 Zeki KARAGÜLLE - 14 minutes BALNEOLOGICAL TREATMENTS WITH NATURAL HYDROGEN SULFIDE (H2S) Waters Link L3 Constantin Florin Dragan, Liliana Padure, Gelu Onose - 12 minutes SPECIFIC ADVANCED QUANTIFICATIONS ON THE RELATIONSHIP BETWEEN THE ANGULATION OF THE MAIN SCOLIOTIC CURVE AND LEG SWING IN THE GAIT PHASES, IN CHILDREN AND ADOLESCENTS WITH AND WITHOUT POSTURAL TREATMENT Link L4 Irina ALBADI, Camelia CIOBOTARU, Andreea-Alexandra LUPU, Ionela BALASA, Claudiu FATU, Enghin SACHIR, Gelu ONOSE - 12 minutes A MULTIMODAL APPROACHES TO MANAGE REHABILITATION THERAPY OF DISFUNCTIONALS ASPECTS TO A PACIENT WITH GOUT, MIELLITUS DIABETES, ATRIAL FIBRILATION AND MIDDLE CEREBRAL ARTERY STROKE Link L5 ELENA RAEVSCHI - 12 minutes PREVENTION CONSIDERATIONS IN Cardiovascular Diseases regarding the premature mortality reduction Link L6 ANIȘOARA CIMIL - 12 minutes THE EFFECTIVENESS OF THE REHABILITATION PROGRAMME ACCORDING TO THE ETIOPATHOGENESIS OF PROSTHETIC JOINT PATHOLOGY Link L7 TRAIAN -VIRGILIU SURDU, Monica SURDU, Olga SURDU - 10 minutes FOURTH INDUSTRIAL REVOLUTION (INDUSTRY 4.0) AND MODERN THERMAL MEDICINE (THERME 4.0) IN XXIST CENTURY Link L8 Gabriela DOGARU, Akos MOLNAR, Marieta MOTRICALA - 10 minutes EFFECTS OF CARBONATED MINERAL WATER AND MOFETTE IN BĂILE TUŞNAD IN EXPERIMENTALLY INDUCED ISCHEMIC HEART DISEASE Link L9 Q & A – 12 minutes Authors Title Abstract Aurelian Anghelescu, Valentin Deaconu, Catalina Axente,Elena Constantin, Gelu Onose - 12 minutes THERAPEUTIC DIFFICULTIES IN A YOUNG PATIENT WITH MULTIDRUG RESISTANT EPILEPSY (NEEDING VAGAL NERVE ELECTROSTIMULATION), SEQUELAE AFTER CONGENITAL VASCULAR CEREBRAL MALFORMATION, WITH CHRONIC GAIT IMPAIRMENTS AND RECENT TRAUMATIC BRAIN COMPLICATION Link L10 Luminița NIRLU, Alexandru G. STAVRICĂ, Laura Georgiana Popescu, Ana Carmen Albeșteanu, Ali-Osman Saglam, Gelu Onose - 12 minutes DIAGNOSTIC PARTICULARITIES AND MULTIMODAL THERAPEUTIC AND REHABILITATION APPROACHES TO A COMPLEX CASE OF POST ISCHEMIC STROKE WITH DYSPHAGIA AND DYSPHONIA, ASSOCIATING MILLARD-GUBLER AND WALLENBERG SYNDROMES - CASE REPORT Link L11 Cristina Octaviana DAIA, Croitoru Stefana, Mariana Axente, Gelu ONOSE - 14 minutes IONTOPHORESIS AND LASER APPLICATIONS IN FACIAL NERVE PALSY Link L12 Doina Maria MOLDOVAN, Gabriela DOGARU - 12 minutes SPLINTING VERSUS SURGICAL TREATMENT IN MALLET FINGER Link L13 Doina Maria MOLDOVAN, Gabriela DOGARU - 12 minutes EARLY REHABILITATION IN PATIENT AFTER TREATMENT FOR DISTAL RADIUS FRACTURE Link L14 Liliana PADURE, Raluca PETCU, Anca Irina GRIGORIU - 12 minutes THE IMPACT OF MULTIFACTORIAL GAIT ANALYSIS ON THE DIAG
科学计划口头报告作者标题摘要康斯坦丁·蒙泰努、米哈伊尔·霍特图、戴安娜·蒙泰努和加布里埃拉·多加鲁-12分钟心理学专业-国际数据输入，国家OUTPUTSLink L1UMBERTO SOLIMENE-14分钟气候与健康：老科学的新挑战L2 Zeki KARAGÜLLE-14分钟天然硫化氢（H2S）水的生物治疗Link L3Constantin Florin Dragan，Liliana Padure，Gelu Onose-12 minutes关于儿童和青少年在接受和不接受术后治疗的增益阶段的主要评分曲线的角度与腿部摆动之间关系的特殊高级量化Link L4Irina ALBADI、Camellia CIOBOTARU、Andreea Alexandra LUPU、Ionela BALASA、Claudiu FATU、Enghin SACHIR，Gelu ONOSE-12分钟管理GOUT、MIELLITUS糖尿病患者功能障碍康复治疗的多模式方法，心房纤维化和大脑中动脉血栓形成L5ELENA RAEVSCHI-12分钟心血管疾病中关于过早降低死亡率的预防性考虑Link L6ANIȘOARA CIMIL-12分钟根据前列腺关节病理学病因制定的康复计划的有效性Link L7TRAIAN-VIRGIU SURDU，Monica SURDU，奥尔加·苏尔杜-10分钟21世纪的工业革命（工业4.0）和现代热医学（热医学4.0）链接L8Gabriela DOGARU、Akos MOLNAR、Marieta MOTRICALA-10分钟BĂILE TUŞNAD中碳酸化矿泉水和MOSFET在实验诱导的缺血性心脏病中的影响链接L9问答-12分钟作者标题摘要Aurelian Anghelescu、Valentin Deaconu，Catalina Axente，Elena Constantin，Gelu Onose-12分钟患有多药耐药性癫痫（需要迷走神经电刺激）、先天性血管性脑畸形后后遗症、慢性增益障碍和近期创伤性脑并发症的年轻患者的治疗困难Link L10LuminițA NIRLU，Alexandru G.STAVRICĂ，Laura Georgiana Popescu，Ana Carmen Albeșteanu，Ali Osman Saglam，Gelu Onose-12分钟脑缺血后卒中伴脑脊髓炎和脑脊髓炎的复杂病例的脑脊髓炎特殊性和多模式治疗和康复方法，将MILLARD-GUBLER和WALLENBERG综合征联系起来-病例报告链接L11Christina Octaviana DAIA，Croitoru Stefana，Mariana Axente，Gelu ONOSE-14分钟PALSYLink L12Doina Maria MOLDOVAN，Gabriela DOGARU-12分钟MALLET FINGER Link L13Doina Maria MOLDOVIN，Gabriera DOGARU 12分钟患者桡骨远端骨折Link L14Liliana PADURE治疗后的早期康复，Anca Irina GRIGORIU-12分钟多因素增益分析对儿童行走障碍诊断和康复的影响链接L15 Valerica Creanga Zarnescu，Ana Maria Fatu，Mihaela Lungu，Violeta Sapira，Anamaria Ciubara-12分钟失调症患者康复的可能性链接L16Cristina DAIA，Simona SCHEK，Stefana CROITORU，Alina GHERGHHICEANU，Gelu ONOSE-12分钟一名严重左半患者在肾间血肿连接L17Elena VIZITIU后的可避免的康复结果，Mihai CONSTANTINESCU，Sînziana Călina SILIȘTEANU-12分钟治疗性游泳在学龄前儿童中遗留“C”型SCOLIOSIS的预防中的作用链接L18问答-12分钟作者：Alexandru G.STAVRICĂ，LuminiţA Nirlu，Laura Georgiana Popescu，Ana Carmen AlbeşTEANU，Gelu ONOSE-12分钟与一例严重CCT-双前额叶-基底部和口部挫伤后的四肢瘫痪（伴伴截瘫）相关的康复治疗方法。链接L19Ana Maria Bumbea、Otilia Rogoveanu、Carmen、Albu Rodica Traistaru、Catalin、Bostina、Bogdan Stefan Bumbia、Roxana Dumitrascu，Borcan Madalina神经病患者的空间管理Link L20Laura Georgiana Popescu，Luminița Nirlu，Ana Carmen Albeșteanu，Ali Osman Saglam，Gelu Onose-12分钟复杂治疗-康复管理的策略，逐步，在一个大的多器官环境中的CT后精神认知障碍患者中-病例报告链接L21Adrian MELNIC，Oleg PASCAL-12分钟制定策略以解决中风康复中的复杂性。链接L22Dorin Gheorghe TRIFF，Simona POP-12分钟肌肉关节松弛的原发性疾病。康复治疗链接L23的诊断标准和原则Catalin Ionite，Dragos Arotaritei，Mihai Ilea，Mariana Rotariu-12分钟弹性带在踝关节扭伤康复中的应用链接L24 Mariana Rotari，Marius Turnea，Calin Corciova，Catalin Ionite-12分钟立方体疗法在GERIATRICS Link L25CristianŞtefan LIUŞNEA手部关节炎恢复中的作用-12分钟舒适和健康。 概念分娩链接L26Adriana LUPU-12分钟心血管疾病患者肌肉骨骼疼痛及其特殊性的NSAID治疗链接L27问答-12分钟作者标题AbstractMihaela MANDU、Cristinel Dumitru BADIU、Raluca PETCU、Cosmin OPREA、Gelu ONOSE-12分钟临床进化特殊性和多模式治疗-康复，以及通过相关的CARES，方法，在多病理背景下的缺血性心脏-脑卒中后的偏瘫链接L28Ana Carmen Albestanu，Laura Georgiana Popescu，LuminițA Nirlu，Ali Osman Saglam，Gelu Onose-12分钟综合-复杂病理中的康复治疗方法，包括可能演变的分歧类型-病例报告链接L29Liliana PADURE，Cristian Adam，Laura Fierbienteanu-12分钟治疗-医疗康复中的预后因素链接L30Prof。Alexandru Vlad Ciurea-20分钟NEUROSURGERYLink L31Valerica CREANGA-ZARNESCU，Ana Maria FATU，Anamaria CIUBARA，Violeta SAPI
{"title":"Romanian Congress of Physical and Rehabilitation Medicine and Balneology, Galați, 4-6 September 2019 - Congress Abstracts","authors":"","doi":"10.12680/balneo.2019.276","DOIUrl":"https://doi.org/10.12680/balneo.2019.276","url":null,"abstract":"Scientific Program\u0000Oral Presentations\u0000 Authors\u0000\u0000Title\u0000\u0000Abstract\u0000\u0000CONSTANTIN MUNTEANU, Mihail HOTETEU, Diana MUNTEANU, Gabriela DOGARU \u0000\u0000- 12 minutes\u0000\u0000PERSPECTIVES OF BALNEOLOGY - INTERNATIONAL DATA INPUTS, NATIONAL OUTPUTS\u0000\u0000Link L1\u0000\u0000UMBERTO SOLIMENE \u0000\u0000- 14 minutes\u0000\u0000CLIMATE AND HEALTH: A NEW CHALLENGE FOR AN OLD SCIENCE\u0000\u0000\u0000Link L2 \u0000\u0000Zeki KARAGÜLLE \u0000\u0000- 14 minutes\u0000\u0000BALNEOLOGICAL TREATMENTS WITH NATURAL HYDROGEN SULFIDE (H2S) Waters\u0000\u0000Link L3\u0000\u0000Constantin Florin Dragan, Liliana Padure, Gelu Onose \u0000\u0000- 12 minutes\u0000\u0000SPECIFIC ADVANCED QUANTIFICATIONS ON THE RELATIONSHIP BETWEEN THE ANGULATION OF THE MAIN SCOLIOTIC CURVE AND LEG SWING IN THE GAIT PHASES, IN CHILDREN AND ADOLESCENTS WITH AND WITHOUT POSTURAL TREATMENT\u0000\u0000Link L4\u0000\u0000Irina ALBADI, Camelia CIOBOTARU, Andreea-Alexandra LUPU, Ionela BALASA, Claudiu FATU, Enghin SACHIR, Gelu ONOSE \u0000\u0000- 12 minutes\u0000\u0000A MULTIMODAL APPROACHES TO MANAGE REHABILITATION THERAPY OF DISFUNCTIONALS ASPECTS TO A PACIENT WITH GOUT, MIELLITUS DIABETES, ATRIAL FIBRILATION AND MIDDLE CEREBRAL ARTERY STROKE\u0000\u0000Link L5\u0000\u0000ELENA RAEVSCHI\u0000\u0000- 12 minutes\u0000\u0000PREVENTION CONSIDERATIONS IN Cardiovascular Diseases regarding the premature mortality reduction\u0000\u0000Link L6\u0000\u0000ANIȘOARA CIMIL \u0000\u0000- 12 minutes\u0000\u0000THE EFFECTIVENESS OF THE REHABILITATION PROGRAMME ACCORDING TO THE ETIOPATHOGENESIS OF PROSTHETIC JOINT PATHOLOGY \u0000\u0000Link L7\u0000\u0000TRAIAN -VIRGILIU SURDU, Monica SURDU, Olga SURDU\u0000\u0000- 10 minutes\u0000\u0000FOURTH INDUSTRIAL REVOLUTION (INDUSTRY 4.0) AND MODERN THERMAL MEDICINE (THERME 4.0) IN XXIST CENTURY \u0000\u0000Link L8\u0000\u0000Gabriela DOGARU, Akos MOLNAR, Marieta MOTRICALA \u0000\u0000- 10 minutes\u0000\u0000EFFECTS OF CARBONATED MINERAL WATER AND MOFETTE IN BĂILE TUŞNAD IN EXPERIMENTALLY INDUCED ISCHEMIC HEART DISEASE \u0000\u0000Link L9\u0000\u0000Q & A – 12 minutes\u0000\u0000 Authors\u0000\u0000Title\u0000\u0000Abstract\u0000\u0000Aurelian Anghelescu, Valentin Deaconu, Catalina Axente,Elena Constantin, Gelu Onose\u0000\u0000- 12 minutes\u0000\u0000THERAPEUTIC DIFFICULTIES IN A YOUNG PATIENT WITH MULTIDRUG RESISTANT EPILEPSY (NEEDING VAGAL NERVE ELECTROSTIMULATION), SEQUELAE AFTER CONGENITAL VASCULAR CEREBRAL MALFORMATION, WITH CHRONIC GAIT IMPAIRMENTS AND RECENT TRAUMATIC BRAIN COMPLICATION\u0000\u0000Link L10\u0000\u0000Luminița NIRLU, Alexandru G. STAVRICĂ, Laura Georgiana Popescu, Ana Carmen Albeșteanu, Ali-Osman Saglam, Gelu Onose \u0000\u0000- 12 minutes\u0000\u0000DIAGNOSTIC PARTICULARITIES AND MULTIMODAL THERAPEUTIC AND REHABILITATION APPROACHES TO A COMPLEX CASE OF POST ISCHEMIC STROKE WITH DYSPHAGIA AND DYSPHONIA, ASSOCIATING MILLARD-GUBLER AND WALLENBERG SYNDROMES - CASE REPORT \u0000\u0000Link L11\u0000\u0000Cristina Octaviana DAIA, Croitoru Stefana, Mariana Axente, Gelu ONOSE - 14 minutes\u0000\u0000IONTOPHORESIS AND LASER APPLICATIONS IN FACIAL NERVE PALSY\u0000\u0000Link L12\u0000\u0000Doina Maria MOLDOVAN, Gabriela DOGARU - 12 minutes\u0000\u0000SPLINTING VERSUS SURGICAL TREATMENT IN MALLET FINGER \u0000\u0000Link L13\u0000\u0000Doina Maria MOLDOVAN, Gabriela DOGARU - 12 minutes\u0000\u0000EARLY REHABILITATION IN PATIENT AFTER TREATMENT FOR DISTAL RADIUS FRACTURE \u0000\u0000Link L14\u0000\u0000Liliana PADURE, Raluca PETCU, Anca Irina GRIGORIU\u0000\u0000- 12 minutes\u0000\u0000THE IMPACT OF MULTIFACTORIAL GAIT ANALYSIS ON THE DIAG","PeriodicalId":43815,"journal":{"name":"Balneo Research Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47965263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-03DOI: 10.12680/balneo.2019.269
A. Andreev, Sergey Puhlik, O. Melnikov, I. Tagunova, S. Gushcha
Introduction: The component of the lymphopharyngeal ring is the lingual tonsil (LT), located on the root of the tongue. With pathological changes in the lymphoid tissue of the pharynx, surgical removal of the tonsils, as a result of increased antigenic load, a compensatory increase in LT is observed – «lingual tonsillar hypertrophy». This is observed against the background of age-related involutive changes, when the remaining elements of the lymphopharyngeal ring begin to perform anti-antigenic and adaptive activity. The processes taking place in, the structure of the LT, which is familiar to the body, changes - the receptor apparatus creates pathological impulses from the organ. The severity of clinical manifestations correlates with the degree of increase in LT. The emphasis on these manifestations, psychosomatic conditions, create a complex of pathological sensations that violate the quality of patients’ life. The goal and objectives of the study are aimed at improving the quality of patients’ life with lingual tonsil hypertrophy (LTH), by developing effective methods of diagnosis and treatment, assessing the role of the immunoregulatory shift in the pathogenesis of LTH of the possibility of their correction by the action of a physical factor (cold destruction). Materials and methods: When examining 850 people who underwent complex research and instrumental diagnostics in connection with the pathology of ENT organs, 119 people (the main group) were diagnosed with different degrees of LTH, with control of 30 healthy people. Cryosurgical treatment was offered to 76 patients who used the method for treating of lingual tonsil hypertrophy by cryodestruction using a hook-shaped applicator with a heat-insulating nozzle on the back surface, an individual polyethylene cap, and a cryoapparatus. Results and discussions: With LTH, an increase in the volume and mass of tissues forming the morphological basis of the tonsil was detected: the main substance was an increase in the number and size of layers of coarse fibrous fibers, fields of fat cells, and the growth of mucous glands. The mucous membrane, thinning, undergoes dystrophic-degenerative changes. The rate of proliferation correlates with the severity of inflammation, the causes of which are multifactorial, individual. There is an increased sensitivity reaction to microbial and household allergens, an increase in the content of antibodies in the blood to LT tissues, a change in microbiocinosis of the pharyngeal mucosa, and vegetation of non-resident microflora. As a result of cryosurgical treatment in 56 (73.68%) cases, a decrease in the volume of LT tissue was observed. The deep layers, partially absorbed, were replaced by healthy tissues, the surface layers were rejected with the formation of an atrophic scar or regenerate, the structure of which was close to organotypic. The cause of pathological impulse was eliminated, clinical indicators were normalized, the quality of life of patients was impro
{"title":"Lingual tonsils hypertrophy and possibility of its correction by physical factors","authors":"A. Andreev, Sergey Puhlik, O. Melnikov, I. Tagunova, S. Gushcha","doi":"10.12680/balneo.2019.269","DOIUrl":"https://doi.org/10.12680/balneo.2019.269","url":null,"abstract":"Introduction: The component of the lymphopharyngeal ring is the lingual tonsil (LT), located on the root of the tongue. With pathological changes in the lymphoid tissue of the pharynx, surgical removal of the tonsils, as a result of increased antigenic load, a compensatory increase in LT is observed – «lingual tonsillar hypertrophy». This is observed against the background of age-related involutive changes, when the remaining elements of the lymphopharyngeal ring begin to perform anti-antigenic and adaptive activity. The processes taking place in, the structure of the LT, which is familiar to the body, changes - the receptor apparatus creates pathological impulses from the organ. The severity of clinical manifestations correlates with the degree of increase in LT. The emphasis on these manifestations, psychosomatic conditions, create a complex of pathological sensations that violate the quality of patients’ life. The goal and objectives of the study are aimed at improving the quality of patients’ life with lingual tonsil hypertrophy (LTH), by developing effective methods of diagnosis and treatment, assessing the role of the immunoregulatory shift in the pathogenesis of LTH of the possibility of their correction by the action of a physical factor (cold destruction). Materials and methods: When examining 850 people who underwent complex research and instrumental diagnostics in connection with the pathology of ENT organs, 119 people (the main group) were diagnosed with different degrees of LTH, with control of 30 healthy people. Cryosurgical treatment was offered to 76 patients who used the method for treating of lingual tonsil hypertrophy by cryodestruction using a hook-shaped applicator with a heat-insulating nozzle on the back surface, an individual polyethylene cap, and a cryoapparatus.\u0000Results and discussions: With LTH, an increase in the volume and mass of tissues forming the morphological basis of the tonsil was detected: the main substance was an increase in the number and size of layers of coarse fibrous fibers, fields of fat cells, and the growth of mucous glands. The mucous membrane, thinning, undergoes dystrophic-degenerative changes. The rate of proliferation correlates with the severity of inflammation, the causes of which are multifactorial, individual. There is an increased sensitivity reaction to microbial and household allergens, an increase in the content of antibodies in the blood to LT tissues, a change in microbiocinosis of the pharyngeal mucosa, and vegetation of non-resident microflora. As a result of cryosurgical treatment in 56 (73.68%) cases, a decrease in the volume of LT tissue was observed. The deep layers, partially absorbed, were replaced by healthy tissues, the surface layers were rejected with the formation of an atrophic scar or regenerate, the structure of which was close to organotypic. The cause of pathological impulse was eliminated, clinical indicators were normalized, the quality of life of patients was impro","PeriodicalId":43815,"journal":{"name":"Balneo Research Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42206459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-03DOI: 10.12680/balneo.2019.257
Constantin Munteanu, D. Munteanu, M. Hoteteu, G. Dogaru
Introduction. Balneology has a long European and Asian tradition and Romania can be the cornerstone of international bridges in this area due to its geographical position, legendary tradition and extraordinary natural resources of all kind. The use of thermal and mineral springs on the territory of the country for health and treatment purposes is a tradition with a history of more than two thousand years. Unique spa resources, such as thermal and mineral springs, mud, mofettes, saline microclimate and bioclimate (sedative or relaxing, exciting of marine seaside or plains, stimulant or tonic), are used successfully in the sphere of health care services, preventive medical actions, rehabilitation and wellness. Legend of Hercule bathing in Cerna's waters is a proof of the use of thermal waters long before the Roman conquest. This tradition exists in almost all civilizations. Today it maintains its usefulness and is spread across all continents, mainly in the Middle East and South and East Europe, Asia (Middle East, Japan, China, Turkey), South America (Argentina, Mexico, Colombia) and North Africa (Morocco, Tunisia) (244-249). Material and method. This article is a sistematic and summarizing review of all published articles by Balneo Research Journal in its ten years of existence, from november 2010 until September 2019. All the ten volumes and more than 250 articles were analized in order to understand the main thematic of the articles, the more usefull scientific concepts, the realistic benefits of the published articles for the development of Balneology. Results and discussions. Analizing an article database of about 250 publised articles in Balneo Research Journal can be of real impact on the development of the field of Balneology but also can drive the future of the jurnal to better understand its implications in the scientific arena. Conclusions. Main scientific concepts with which Balneology is operating, interdisciplinary connections and interests were focused on ideas to have in mind by the authors and readers of this article. Key words: Balneology, Balneotherapy, Balneo Research Journal, Natural therapeutic factors, Balneary Resort,
介绍。Balneology在欧洲和亚洲有着悠久的传统，罗马尼亚凭借其地理位置、传奇传统和各种非凡的自然资源，可以成为该领域国际桥梁的基石。在我国领土上为保健和治疗目的使用温泉和矿泉是一项具有两千多年历史的传统。独特的温泉资源，如热泉和矿泉、泥浆、mofettes、盐碱小气候和生物气候(镇静或放松、海洋海滨或平原的兴奋、兴奋剂或滋补品)，成功地用于保健服务、预防性医疗行动、康复和保健领域。传说赫拉克勒在塞尔纳的水中沐浴，证明了早在罗马征服之前就已经使用了热水。这一传统几乎存在于所有文明中。今天，它仍然有用，并在各大洲传播，主要是在中东和南欧和东欧，亚洲(中东，日本，中国，土耳其)，南美(阿根廷，墨西哥，哥伦比亚)和北非(摩洛哥，突尼斯)(244-249)。材料和方法。本文系统总结了Balneo Research Journal从2010年11月到2019年9月的十年间发表的所有文章。为了了解文章的主题，更有用的科学概念，发表的文章对Balneology发展的现实效益，对所有10卷和250多篇文章进行了分析。结果和讨论。分析Balneo Research Journal上约250篇发表文章的文章数据库可以对Balneo领域的发展产生真正的影响，但也可以推动期刊的未来，以更好地理解其在科学领域的含义。Balneology运行的主要科学概念、跨学科联系和兴趣集中在本文作者和读者心中的想法上。关键词:Balneology, balnetherapy, Balneo Research Journal，天然治疗因子，Balneary Resort，
{"title":"Balneotherapy – medical, scientific, educational and economic relevance reflected by more than 250 articles published in Balneo Research Journal","authors":"Constantin Munteanu, D. Munteanu, M. Hoteteu, G. Dogaru","doi":"10.12680/balneo.2019.257","DOIUrl":"https://doi.org/10.12680/balneo.2019.257","url":null,"abstract":"Introduction. Balneology has a long European and Asian tradition and Romania can be the cornerstone of international bridges in this area due to its geographical position, legendary tradition and extraordinary natural resources of all kind. The use of thermal and mineral springs on the territory of the country for health and treatment purposes is a tradition with a history of more than two thousand years. Unique spa resources, such as thermal and mineral springs, mud, mofettes, saline microclimate and bioclimate (sedative or relaxing, exciting of marine seaside or plains, stimulant or tonic), are used successfully in the sphere of health care services, preventive medical actions, rehabilitation and wellness. Legend of Hercule bathing in Cerna's waters is a proof of the use of thermal waters long before the Roman conquest. This tradition exists in almost all civilizations. Today it maintains its usefulness and is spread across all continents, mainly in the Middle East and South and East Europe, Asia (Middle East, Japan, China, Turkey), South America (Argentina, Mexico, Colombia) and North Africa (Morocco, Tunisia) (244-249). \u0000Material and method. This article is a sistematic and summarizing review of all published articles by Balneo Research Journal in its ten years of existence, from november 2010 until September 2019. All the ten volumes and more than 250 articles were analized in order to understand the main thematic of the articles, the more usefull scientific concepts, the realistic benefits of the published articles for the development of Balneology.\u0000Results and discussions. Analizing an article database of about 250 publised articles in Balneo Research Journal can be of real impact on the development of the field of Balneology but also can drive the future of the jurnal to better understand its implications in the scientific arena.\u0000Conclusions. Main scientific concepts with which Balneology is operating, interdisciplinary connections and interests were focused on ideas to have in mind by the authors and readers of this article.\u0000Key words: Balneology, Balneotherapy, Balneo Research Journal, Natural therapeutic factors, Balneary Resort,","PeriodicalId":43815,"journal":{"name":"Balneo Research Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43011967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-03DOI: 10.12680/balneo.2019.270
Paul-Mihai Boarescu, Ioana Boarescu, I. Bocșan, R. Pop, D. Gheban, A. Bulboacă, G. Dogaru, S. Bolboacă
Introduction: Acute myocardial infarction (AMI) is an important acute disease of myocardial tissue, that occurs as a result of an imbalance between coronary blood supply and myocardial demand. Isoproterenol (ISO) is a synthetic catecholamine, a beta-adrenergic agonist that produces extensive biochemical, functional, and histological alterations in the heart, characteristic for AMI. The present study has been designed to identify the best dose of ISO that induces electrocardiogram (ECG) alterations, enzymatic reaction, and histopathological changes characteristic of AMI. Material and method: AMI was induced to Wistar-Bratislava white male rats, using three different subcutaneous doses of ISO (85 mg/kg bw, 100 mg/kg bw, and 150 mg/kg bw). ISO was administrated twice, with the second dose at 24h after the initial one. The ECGs were recorded at 24 hours after the last dose of ISO. Blood samples were collected for measurement of creatine kinase (CK), and CK-MB serum levels, and the hearts were excised and prepared for histopathologic examination. Results and discussions: All doses of ISO induced alterations in the ECG patterns such as increased heart rate and prolongation of QT and QTc intervals. Depression of the ST segment coupled with marked T wave inversion were observed at the doses of 100 mg/kg bw and 150 mg/kg bw of ISO. All doses of ISO induced an elevation of CK and CK-MB with highest levels observed for the dose of 150 mg/kg bw. Histopathologic examination revealed subendocardial AMI lesions for all doses tested. Conclusions: ISO in doses of 100 mg/kg and 150 mg/kg is useful for induction of infarct-like lesion on ECG, increased levels of myocardial necrosis enzymes and morphological changes characteristic for AMI.
{"title":"Experimental model of acute myocardial infarction for evaluation of prevention and rehabilitation strategies in cardiovascular diseases – a pilot study","authors":"Paul-Mihai Boarescu, Ioana Boarescu, I. Bocșan, R. Pop, D. Gheban, A. Bulboacă, G. Dogaru, S. Bolboacă","doi":"10.12680/balneo.2019.270","DOIUrl":"https://doi.org/10.12680/balneo.2019.270","url":null,"abstract":"Introduction: Acute myocardial infarction (AMI) is an important acute disease of myocardial tissue, that occurs as a result of an imbalance between coronary blood supply and myocardial demand. Isoproterenol (ISO) is a synthetic catecholamine, a beta-adrenergic agonist that produces extensive biochemical, functional, and histological alterations in the heart, characteristic for AMI. The present study has been designed to identify the best dose of ISO that induces electrocardiogram (ECG) alterations, enzymatic reaction, and histopathological changes characteristic of AMI. Material and method: AMI was induced to Wistar-Bratislava white male rats, using three different subcutaneous doses of ISO (85 mg/kg bw, 100 mg/kg bw, and 150 mg/kg bw). ISO was administrated twice, with the second dose at 24h after the initial one. The ECGs were recorded at 24 hours after the last dose of ISO. Blood samples were collected for measurement of creatine kinase (CK), and CK-MB serum levels, and the hearts were excised and prepared for histopathologic examination. Results and discussions: All doses of ISO induced alterations in the ECG patterns such as increased heart rate and prolongation of QT and QTc intervals. Depression of the ST segment coupled with marked T wave inversion were observed at the doses of 100 mg/kg bw and 150 mg/kg bw of ISO. All doses of ISO induced an elevation of CK and CK-MB with highest levels observed for the dose of 150 mg/kg bw. Histopathologic examination revealed subendocardial AMI lesions for all doses tested. Conclusions: ISO in doses of 100 mg/kg and 150 mg/kg is useful for induction of infarct-like lesion on ECG, increased levels of myocardial necrosis enzymes and morphological changes characteristic for AMI.","PeriodicalId":43815,"journal":{"name":"Balneo Research Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43213533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-03DOI: 10.12680/balneo.2019.264
A. Ciubean, Laszlo Irsay, R. Ungur, V. Ciortea, Ileana Monica Borda, B. G. Dogaru, A. Trifa, A. Buzoianu
Introduction: Osteoporosis has a strong genetic contribution, and several genes have been shown to influence bone mineral density. Variants in the human genome are considered important causes of differences in drug responses observed in clinical practice. In terms of bone mineral density, about 26–53% of patients do not respond to amino-bisphosphonate therapies, of which alendronate is the most widely used. Material and method: The current study is prospective, observational, analytical, longitudinal and cohort type. It included 25 postmenopausal women treated with alendronate for 1 year. Bone mineral density at lumbar spine and proximal femur was measured and bone turnover markers (C-terminal telopeptide of type I collagen and procollagen 1N-terminal propeptide) were evaluated at 0 and 12 months of treatment. Six single nucleotide polymorphisms in osteoporosis-candidate genes were genotyped (FDPS rs2297480, LRP5 rs3736228, SOST rs1234612, VKORC1 rs9934438, GGPS1 rs10925503 and RANKL rs2277439). Treatment response was evaluated by percentage changes in bone mineral density and bone turnover markers. Results: The heterozygous CT of FDPS rs2297480 showed lower increases in BMD values in the lumbar spine region and the homozygous CC of the GGPS1 rs10925503 showed lower increases in terms of BMD at the total hip region. No association was found for LRP5 rs3736228, SOST rs1234612, VKORC1 rs9934438 and RANKL rs2277439. Conclusions: Romanian postmenopausal women with osteoporosis carrying the CT genotype of FDPS rs2297480 or the CC genotype of GGPS1 rs10925503 could have an unsatisfactory response to alendronate treatment. Key words: osteoporosis; genetic polymorphism; alendronate; bone mineral density; bone turnover markers,
{"title":"Genetic polymorphisms and their influence on therapeutic response to alendronate-a pilot study","authors":"A. Ciubean, Laszlo Irsay, R. Ungur, V. Ciortea, Ileana Monica Borda, B. G. Dogaru, A. Trifa, A. Buzoianu","doi":"10.12680/balneo.2019.264","DOIUrl":"https://doi.org/10.12680/balneo.2019.264","url":null,"abstract":"Introduction: Osteoporosis has a strong genetic contribution, and several genes have been shown to influence bone mineral density. Variants in the human genome are considered important causes of differences in drug responses observed in clinical practice. In terms of bone mineral density, about 26–53% of patients do not respond to amino-bisphosphonate therapies, of which alendronate is the most widely used. \u0000Material and method: The current study is prospective, observational, analytical, longitudinal and cohort type. It included 25 postmenopausal women treated with alendronate for 1 year. Bone mineral density at lumbar spine and proximal femur was measured and bone turnover markers (C-terminal telopeptide of type I collagen and procollagen 1N-terminal propeptide) were evaluated at 0 and 12 months of treatment. Six single nucleotide polymorphisms in osteoporosis-candidate genes were genotyped (FDPS rs2297480, LRP5 rs3736228, SOST rs1234612, VKORC1 rs9934438, GGPS1 rs10925503 and RANKL rs2277439). Treatment response was evaluated by percentage changes in bone mineral density and bone turnover markers.\u0000 Results: The heterozygous CT of FDPS rs2297480 showed lower increases in BMD values in the lumbar spine region and the homozygous CC of the GGPS1 rs10925503 showed lower increases in terms of BMD at the total hip region. No association was found for LRP5 rs3736228, SOST rs1234612, VKORC1 rs9934438 and RANKL rs2277439.\u0000Conclusions: Romanian postmenopausal women with osteoporosis carrying the CT genotype of FDPS rs2297480 or the CC genotype of GGPS1 rs10925503 could have an unsatisfactory response to alendronate treatment.\u0000Key words: osteoporosis; genetic polymorphism; alendronate; bone mineral density; bone turnover markers,","PeriodicalId":43815,"journal":{"name":"Balneo Research Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48312672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-03DOI: 10.12680/balneo.2019.275
C. Bochiș, L. Lazăr, C. Nistor-Cseppento, F. Cioară, N. Paşcalău
Introduction. The two compartments, disco-temporal and condilo-discal, which make up the temporo-mandibular joint, fulfill the functions of the stomatognathic system, namely: phonation, mastication and swallowing. The temporo-mandibular degenerative pathology is one of the 5 clinical entities given by the American Academy of Orofacial Pain in 1993. The symptoms are varied, dominated by pain, impaired joint mobility, cracks, sensation of muscle fatigue in the masseter and temporal muscles. Most cases benefit from conservative treatment, consisting of anti-allergic and anti-inflammatory medication, specific orthodontic treatment, electrotherapy (TENS, ultrasound, magnetodiaflux, laser), kinesiotherapy. 2-5% of patients require surgery. Material and method. We performed a retrospective study, over a 9-year period (January 2010-March 2019), in which we included 503 patients who went to the Timisoara Oro-Maxillofacial Surgery Clinic, with a definite diagnosis of temporomandibular algodisfunctional syndrome, of different etiologies, between the ages of 6 and 85 years. We evaluated the etiology of temporomandibular algodisfunctional syndrome, the prevalence of clinical manifestations in temporomandibular osteoarthritis and their evolution after 10 days of conservative treatment. Results and discussions. Pain is present in 100% of cases, the values obtained in these patients with temporomandibular osteoarthritis are between 10 and 40mm. Cracks are present in women in the percentage of 40.8% and 37.9% in men; mobility limitation is found in women in 11% of cases, and in men in 15% of cases. Conclusions. The existence of a protocol for the diagnosis of TM osteoarthritis is essential to establish the treatment plan and prognosis of the disease. The pain from osteoarthritis TM is low intensity, present in all patients; cracks and limiting mobility are present in comparable proportions, regardless of gender. The response to treatment was optimal at 21 days of treatment.
{"title":"Prevalence of clinical manifestations of temporomandibular osteoarthrosis","authors":"C. Bochiș, L. Lazăr, C. Nistor-Cseppento, F. Cioară, N. Paşcalău","doi":"10.12680/balneo.2019.275","DOIUrl":"https://doi.org/10.12680/balneo.2019.275","url":null,"abstract":"Introduction. The two compartments, disco-temporal and condilo-discal, which make up the temporo-mandibular joint, fulfill the functions of the stomatognathic system, namely: phonation, mastication and swallowing. The temporo-mandibular degenerative pathology is one of the 5 clinical entities given by the American Academy of Orofacial Pain in 1993. The symptoms are varied, dominated by pain, impaired joint mobility, cracks, sensation of muscle fatigue in the masseter and temporal muscles. Most cases benefit from conservative treatment, consisting of anti-allergic and anti-inflammatory medication, specific orthodontic treatment, electrotherapy (TENS, ultrasound, magnetodiaflux, laser), kinesiotherapy. 2-5% of patients require surgery. Material and method. We performed a retrospective study, over a 9-year period (January 2010-March 2019), in which we included 503 patients who went to the Timisoara Oro-Maxillofacial Surgery Clinic, with a definite diagnosis of temporomandibular algodisfunctional syndrome, of different etiologies, between the ages of 6 and 85 years. We evaluated the etiology of temporomandibular algodisfunctional syndrome, the prevalence of clinical manifestations in temporomandibular osteoarthritis and their evolution after 10 days of conservative treatment. Results and discussions. Pain is present in 100% of cases, the values obtained in these patients with temporomandibular osteoarthritis are between 10 and 40mm. Cracks are present in women in the percentage of 40.8% and 37.9% in men; mobility limitation is found in women in 11% of cases, and in men in 15% of cases. Conclusions. The existence of a protocol for the diagnosis of TM osteoarthritis is essential to establish the treatment plan and prognosis of the disease. The pain from osteoarthritis TM is low intensity, present in all patients; cracks and limiting mobility are present in comparable proportions, regardless of gender. The response to treatment was optimal at 21 days of treatment.","PeriodicalId":43815,"journal":{"name":"Balneo Research Journal","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2019-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48890835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：