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Virginal breast hypertrophy – An uncommon breast disease 处女乳房肥大-一种罕见的乳房疾病
IF 1 Q3 Medicine Pub Date : 2023-11-08 DOI: 10.1016/j.ijso.2023.100711
Omobolaji Ayandipo , Oluwasanmi Ajagbe , Gbolahan Obajimi , Olusola Idowu , Amos Adeleye , Temidayo Ogundiran

Introduction

Virginal breast hypertrophy VBH with the sobriquet “gigantomastia” is an uncommon condition with sporadic presentation usually in adolescence.

Case presentation

In this retrospective study, eight patients (three case summaries presented, while the clinicopathologic features of all the patients are presented in Table 1) were managed.

Discussion

The age range in this retrospective cohort study is 13–34 years and the series consists predominantly of teenagers, a third had bilateral disease, and the symptoms triad of mastalgia, cosmetic concerns, and psychosocial/esteem issues were present in all the patients. With a third consenting to surgical intervention.

We present what to our knowledge must be in the global literature, one of the few largest accruals of cases of gigantomastia, the VBH, seen over time in our surgical oncology practice.

Conclusion

VBH should be appraised along with other BBD to exclude malignancies and provide prompt and appropriate care whilst limiting complications. A multidisciplinary approach is particularly important and incorporating care for perceived low self-esteem cannot be over-emphasized.

童贞性乳房肥大VBH,俗称“巨乳症”,是一种罕见的情况,通常在青春期零星出现。在本回顾性研究中,对8例患者进行了处理(其中3例病例总结,所有患者的临床病理特征见表1tbl1)。这项回顾性队列研究的年龄范围为13-34岁,主要由青少年组成,三分之一患有双侧疾病,所有患者都存在乳房痛、美容问题和社会心理/自尊问题三重症状。三分之一同意手术干预。我们提出了我们所知的必须在全球文献中,在我们的外科肿瘤学实践中,随着时间的推移,巨大乳房瘤病例的少数最大累积之一,VBH。VBH应与其他BBD一起进行评估,以排除恶性肿瘤,并在限制并发症的同时提供及时和适当的护理。多学科的方法尤其重要,并结合对觉察到的低自尊的照顾再怎么强调也不为过。
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引用次数: 0
The current pathogenicity and potential risk evaluation of Lassa virus to cause mysterious "Disease X" - an update on recent evidences 拉沙病毒引起神秘“X病”的目前致病性和潜在风险评估——最新证据
IF 1 Q3 Medicine Pub Date : 2023-11-08 DOI: 10.1016/j.ijso.2023.100709
Rehnuma Nasim, Md Rabiul Islam
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引用次数: 0
Cholelithiasis in childhood: Report of two cases from Afghanistan and literature review 儿童胆石症:阿富汗2例报告及文献复习
IF 1 Q3 Medicine Pub Date : 2023-11-03 DOI: 10.1016/j.ijso.2023.100705
Turyalai Hakimi , Fazel Rahman Rahmani , Mansoor Aslamzai , Mohammad Anwar Jawed

Introduction

Cholelithiasis is a rare abdominal condition in children. The cause of pediatric cholelithiasis is unclear, and the most commonly occurring type is pigment stones due to hemolytic diseases and other causes such as medications, hepatobiliary tract anomalies, and genetic problems. Asymptomatic patients require monitoring, whereas symptomatic patients require surgical removal of the gall bladder (cholecystectomy), which can be performed using open or laparoscopic techniques. Here, we present two cases of cholelithiasis (symptomatic and asymptomatic) with neglect of proper medical management until a definite diagnosis and surgical treatment.

Case presentation

A 13-year-old and an 11-year-old child were presented with the diagnosis of cholelithiasis to our pediatric surgery department. The earlier patient suffered from jaundice in early childhood and was treated with the traditional method (non-surgical home remedy using an onion). Later, he was diagnosed with multiple gallbladder stones. The later patient was asymptomatic until his hospitalization at the age of 11 years, when he was diagnosed with a single gallbladder stone (epigastric pain after heavy meals as a chief complaint). Both patients were symptomatic, so we decided to plan them for definite treatment. The patients underwent cholecystectomy with no complications and were discharged from the hospital in satisfactory condition.

Clinical discussion

However, cholelithiasis is uncommon in children, but recent reports indicate increased detection of the disease. In developed nations, an increase in childhood obesity has risen the rate of gallstone cases in the pediatric population. Typically, pediatric cholelithiasis is asymptomatic, but symptomatic children may present with biliary colic as the sudden onset of recurrent epigastric or right upper quadrant (RUQ) pain radiating to the back or right shoulder. In young children, the episodes are accompanied by nausea, vomiting, and fever. Many times, the pain develops without precipitating factors, and fat intolerance is an inconsistent feature. The management of cholelithiasis requires a concise work-up regarding its cause in children.

Conclusion

Cholelithiasis has different underlying causative factors. In otherwise healthy children, surgical treatment is only warranted in symptomatic cases.

胆石症是一种罕见的儿童腹部疾病。小儿胆石症的病因尚不清楚,最常见的类型是溶血性疾病和药物、肝胆道异常、遗传问题等其他原因引起的色素结石。无症状的患者需要监测,而有症状的患者需要手术切除胆囊(胆囊切除术),可以使用开放或腹腔镜技术进行。在此,我们报告两例胆石症患者(有症状和无症状),在确诊和手术治疗前均忽视了适当的医疗管理。一个13岁和一个11岁的孩子被诊断为胆石症来到我们的儿科外科。早期患者在儿童早期患有黄疸,采用传统方法(使用洋葱的非手术家庭疗法)治疗。后来,他被诊断出患有多发性胆囊结石。后一名患者直到11岁住院时才出现无症状,当时他被诊断为单一胆囊结石(主诉为大餐后胃脘痛)。两个病人都有症状,所以我们决定对他们进行明确的治疗计划。患者行胆囊切除术,无并发症,出院情况满意。然而,胆石症在儿童中并不常见,但最近的报道表明该病的检出率有所增加。在发达国家,儿童肥胖的增加增加了儿科人群中胆结石病例的发生率。通常,儿童胆石症是无症状的,但有症状的儿童可能表现为突然发作的复发性上腹部或右上象限(RUQ)疼痛放射到背部或右肩。在幼儿中,发作伴有恶心、呕吐和发烧。很多时候,疼痛的发展没有沉淀因素,脂肪不耐受是一个不一致的特征。胆石症的治疗需要对儿童的病因进行简明的检查。结论胆石症有不同的病因。在其他健康的儿童中,只有在有症状的情况下才需要手术治疗。
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引用次数: 0
The mysterious “Disease X” – A correspondence evaluating its public health threat, the global preparedness, and possible ways to avoid next pandemic 神秘的“X疾病”——一份评估其公共卫生威胁、全球防范以及避免下一次大流行的可能方法的通信
IF 1 Q3 Medicine Pub Date : 2023-11-01 DOI: 10.1016/j.ijso.2023.100704
A.S.M. Roknuzzaman , Md. Aminul Haque, Sabrina Sharmin , Md. Rabiul Islam
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引用次数: 0
Unintended consequences of dieting: How restrictive eating habits can harm your health 节食的意外后果:限制性饮食习惯如何损害你的健康
IF 1 Q3 Medicine Pub Date : 2023-11-01 DOI: 10.1016/j.ijso.2023.100703
Ashna Habib, Tooba Ali, Zainab Nazir, Arisha mahfooz, Qurat-ul-Ain Inayat, Md Ariful Haque

The text explores the negative aspects of dieting. Dieting has been more common in recent years as more people strive to adhere to strict food plans in an effort to achieve their desired body weight and form. Unfortunately, this strategy may have unforeseen repercussions that could have a negative impact on one's health. Insufficient calorie intake, for instance, might deprive the body of vital nutrients, resulting in malnutrition and a weakened immune system. Similar to too-restricted diets, irregular periods and even infertility can result from a disruption in the hormonal balance. Furthermore, dieting can lead to psychological distress, which in turn promotes disordered eating behaviors such as binge eating, purging, and other eating disorders. These disorders have the potential to have a long-term negative impact on physical and mental health, and in some situations, they may even be fatal. It's important to exercise caution and knowledge when it comes to various diet regimens that are advertised on social media and online.

这篇文章探讨了节食的负面影响。近年来,随着越来越多的人努力坚持严格的饮食计划,以达到理想的体重和体形,节食变得越来越普遍。不幸的是,这种策略可能会产生不可预见的后果,对一个人的健康产生负面影响。例如,卡路里摄入不足可能会剥夺身体的重要营养,导致营养不良和免疫系统减弱。与过度限制饮食类似,月经不规律甚至不孕都可能是荷尔蒙平衡被破坏的结果。此外,节食会导致心理困扰,这反过来又会导致饮食失调,如暴饮暴食、排便和其他饮食失调。这些疾病有可能对身心健康产生长期的负面影响,在某些情况下甚至可能是致命的。当涉及到社交媒体和网络上宣传的各种饮食方案时,保持谨慎和了解是很重要的。
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引用次数: 0
Resurgence of MERS-CoV in the United Arab Emirates 中东呼吸综合征冠状病毒在阿拉伯联合酋长国卷土重来
IF 1 Q3 Medicine Pub Date : 2023-11-01 DOI: 10.1016/j.ijso.2023.100691
Ranjana Rohilla, Aroop Mohanty, Najim Z. Alshahrani, Laxman Aryal, Prabha Bhandari, Prashant Bashyal, Rashmi Bhatta, Shailaj Bhandari, Ranjit Sah
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引用次数: 0
Concomitantly combined anterior cruciate ligament and posterolateral corner reconstruction: A case report 前交叉韧带联合后外侧角重建1例
IF 1 Q3 Medicine Pub Date : 2023-10-28 DOI: 10.1016/j.ijso.2023.100706
Hoc Nguyen Van, Khanh Nguyen Manh

Introduction

Combined posterolateral corner (PLC) - anterior cruciate ligament (ACL) tears account for 10% of complex knee injuries. In an ACL-PLC injured knee, an untreated PLC injury causes a significant increase in force on the ACL graft and may be a leading cause of graft failure.

Case presentation

A 26-year-old male patient with combined ACL and PLC injury. He was concurrently reconstructed in both ACL and PLC. We used 2 semitendinosus (1 in each knee) and 1 glacilis tendon (in the injured knee). The ACL was reconstructed by one 4-stranded simitendinosus with an all-inside technique and TightRope fixation. The PLC reconstruction utilized one femoral tunnel at the isometric point, graft fixation at the femoral tunnel by TightRope, and at the tibial tunnel by absorbable screw. After a follow-up of 9 months, Cincinnati's score was 70/100 and the IKDC score was B type.

Discussion

The main advantage is that surgeons do not have to care about tendon length and graft diameter compared to the previous method.

Conclusion

Concomitantly combined ACL and PLC reconstruction has good results in remaining knee functions and decreasing ACL reconstruction failure. However, femoral tunnel creation needs to be careful to avoid femoral tunnel intersections.

复合后外侧角(PLC)-前交叉韧带(ACL)撕裂占复杂膝关节损伤的10%。在ACL-PLL损伤的膝关节中,未经治疗的PLC损伤会导致ACL移植物上的力显著增加,可能是移植物失败的主要原因。病例介绍:一名26岁男性患者,合并ACL和PLC损伤。他同时进行了ACL和PLC的重建。我们使用了2个半腱肌(每个膝盖1个)和1个冰川肌腱(受伤的膝盖)。前交叉韧带由一只4股的猴用全内固定技术和TightRope固定重建。PLC重建利用等轴测点处的一个股骨隧道,通过TightRope在股骨隧道处进行移植物固定,并通过可吸收螺钉在胫骨隧道处进行移植固定。经过9个月的随访,辛辛那提的评分为70/100,IKDC评分为B型。讨论与以前的方法相比,主要优点是外科医生不必关心肌腱长度和移植物直径。结论ACL和PLC联合重建能较好地保留膝关节功能,减少ACL重建失败。然而,股骨隧道的创建需要小心,以避免股骨隧道交叉。
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引用次数: 0
Disease X: Combating the next pandemic needs the nifty wastewater-based epidemiology tool X疾病:防治下一次大流行需要基于废水的灵巧流行病学工具
IF 1 Q3 Medicine Pub Date : 2023-10-16 DOI: 10.1016/j.ijso.2023.100701
Ishrat Mohd, Namra Vinay Gohil, ArunSundar MohanaSundaram, Swathi Gurajala, Fabio Fuentes Gandara, Md Rabiul Islam
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引用次数: 0
Assessment of the efficacy of a novel adhesive haemostat using real world, case series data collection 使用真实世界的病例系列数据收集评估一种新型黏附止血剂的疗效
IF 1 Q3 Medicine Pub Date : 2023-10-12 DOI: 10.1016/j.ijso.2023.100690
M. Grosheva , M. Liese , T. Menovsky , R. Rasschaert , D. Galun , N. Maric , P.D. Hayes , I. van Herzeele

Background

Post-operative haemorrhage can lead to significant complications and even mortality. These utilise scarce healthcare resources and increase hospital costs, as well as negatively impacting on patient's quality of life. Haemostats that exhibit additional adhesive properties can reduce the rate of bleeding complications. Standard gelatin sponges have been used safely in surgery for over 75 years but have almost no adhesive properties. This article reports the performance of a novel adhesive gelatin patch in human surgery for the first time.

Methods

A CE-marked gelatin foam patch (TenaTac®, Selentus Science, UK) has been created through a physical modification of the sponge surface, avoiding the need for the addition of blood-derived components or additional chemicals to stimulate adhesion. Real-world, post-approval clinical evaluations of the device were undertaken, and a structured data form was utilised to collect information on the device's performance during these procedures.

Results

In total, 63 evaluations were undertaken by 40 surgeons in 13 countries, covering 29 different surgical procedures. When assessing the adherence of TenaTac, 83 % (48/58) of the surgeons assessed the adhesion as very good or excellent. Both “haemostatic effect” and “time to haemostasis” achieved median scores of 4/5 (IQR 4–5), which equated to “very good” on the questionnaire. When surgeons were asked to compare their experience with TenaTac against their usual haemostat, 91.7 % (55/60) rated it as good, very good or excellent. When surgeons were asked if they would recommend the use of TenaTac, 96.5 % (55/57) of the surgeons responded positively to this question.

Conclusion

Real world evaluation of the novel adhesive patch, TenaTac, has confirmed that it exhibits very good adhesive and haemostatic qualities and could be considered for use by a wide variety of surgical specialities.

背景术后出血可导致严重并发症甚至死亡。这些措施利用了稀缺的医疗资源,增加了医院成本,并对患者的生活质量产生了负面影响。具有额外粘合性能的止血剂可以降低出血并发症的发生率。标准明胶海绵已在外科手术中安全使用超过75年,但几乎没有粘合性能。本文首次报道了一种新型明胶贴片在人体外科手术中的性能。方法通过对海绵表面进行物理改性,制作出CE标记的明胶泡沫贴片(TenaTac®,Selentus Science,UK),避免了添加血液衍生成分或其他化学物质来刺激粘附。对该设备进行了真实世界的批准后临床评估,并使用结构化数据表收集这些过程中设备性能的信息。结果来自13个国家的40名外科医生共进行了63次评估,涵盖了29种不同的外科手术。在评估TenaTac的粘附性时,83%(48/58)的外科医生认为粘附性非常好或非常好。“止血效果”和“止血时间”的中位得分均为4/5(IQR 4-5),在问卷中相当于“非常好”。当外科医生被要求将他们使用TenaTac的经验与他们常用的止血器进行比较时,91.7%(55/60)的人将其评为良好、非常好或优秀。当外科医生被问及是否会建议使用TenaTac时,96.5%(55/57)的外科医生对此问题做出了积极回应。结论对新型粘合贴片TenaTac的真实世界评估证实,它具有非常好的粘合和止血性能,可供各种外科专业使用。
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引用次数: 0
The ‘‘Monstrous tumor’’ of Adrenal gland: A case report and review of literature on adrenal teratomas 肾上腺“巨瘤”:肾上腺畸胎瘤一例报告及文献复习
IF 1 Q3 Medicine Pub Date : 2023-10-11 DOI: 10.1016/j.ijso.2023.100696
Abdullah Saleh AlQattan , Mohammed Abdulmohsen AlSharit , Essra Zakarya Alsaihaty , Samma Tareq Eraqe , Miral Mashhour , Osama Habib Alsaif

Introduction and clinical importance

Teratomas are neoplasms originating from pluripotent cells, rising from more than one or all three embryonic germinal layers. The nomenclature “Teratoma” is derived from the Greek word “teras” which translates to the word “monster”. One of the rarest locations is the adrenal gland, with adrenal teratomas representing only 0.13 % of all adrenal tumors.

Case presentation

A 36-year-old female, morbidly obese, was found to have a right adrenal mass after she presented to our surgical outpatient clinic with a complaint of abdominal pain. The mass was found on an abdominal computed tomography (CT) scan, which revealed a large retroperitoneal lesion measuring 29 × 15 × 22 cm and displacing the IVC, pancreas, duodenum, right kidney, and ascending colon. The differential diagnosis based on the patient's workup was adrenal teratoma, myolipoma, angiolipoma, and liposarcoma. The patient underwent an uneventful open right adrenalectomy. The final histopathology confirmed the diagnosis of a mature right adrenal cystic teratoma weighing 4 kg. The last follow-up was 3 years postoperatively with no evidence of recurrence on CT scan.

Clinical discussion

A thorough discussion of the clinical presentations of the reported cases in the literature including the first reported case in the English literature. Furthermore, the use of the different modalities of diagnosis e.g., Ultrasonography, CT scan, and MRI. Also, the mainstay modality of treatment and the debate of minimal invasive laparoscopic adrenalectomy vs open adrenalectomy. Finally, the discussion of the period of following up the patient after successful operation and the removal of the tumor were presented.

Conclusion

Adrenal teratoma is extremely uncommon entity, with a great percentage of patient presenting with a non-specific presentation or are asymptomatic. Initial diagnosis might be made radiologically. However, a confirmatory diagnosis is based on the histopathological examination. The workup must rule out other possible differential diagnoses, like metastastis or functional tumors. Finally, surgical resection is the mainstay treatment of adrenal teratoma with an excellent survival rate.

引言和临床意义畸胎瘤是起源于多能干细胞的肿瘤,起源于一层或三层以上的胚胎生发层。命名法“Teratoma”源自希腊语单词“teras”,翻译过来就是“怪物”。肾上腺是最罕见的部位之一,肾上腺畸胎瘤仅占所有肾上腺肿瘤的0.13%。病例介绍:一名36岁女性,病态肥胖,因腹痛到我们的外科门诊就诊后,发现右侧肾上腺肿块。肿块是在腹部计算机断层扫描(CT)上发现的,显示腹膜后有一个29×15×22厘米的大病变,移位了IVC、胰腺、十二指肠、右肾和升结肠。根据患者的检查,鉴别诊断为肾上腺畸胎瘤、肌脂肪瘤、血管脂肪瘤和脂肪肉瘤。病人顺利地接受了右肾上腺开放性切除术。最终的组织病理学证实诊断为一个4公斤重的成熟右肾上腺囊性畸胎瘤。最后一次随访是术后3年,CT扫描没有复发的证据。临床讨论对文献中报告病例的临床表现进行彻底讨论,包括英国文献中第一例报告病例。此外,使用不同的诊断方式,如超声、CT扫描和MRI。此外,微创腹腔镜肾上腺切除术与开放式肾上腺切除术的主要治疗方式和争论。最后,对手术成功后的随访时间和肿瘤切除进行了讨论。结论肾上腺畸胎瘤是一种极不常见的实体瘤,有很大比例的患者表现为非特异性或无症状。初步诊断可以通过放射学进行。然而,确诊是基于组织病理学检查。检查必须排除其他可能的鉴别诊断,如转移或功能性肿瘤。最后,手术切除是肾上腺畸胎瘤的主要治疗方法,具有良好的生存率。
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引用次数: 0
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International Journal of Surgery Open
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