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Comparison of the effects of vitamin D and nasal calcitonin spray with nasal calcitonin spray on postoperative abdominal pain: A randomised controlled trial 维生素D和鼻降钙素喷雾剂与鼻降钙素喷雾剂对术后腹痛疗效的比较:一项随机对照试验
IF 1 Q3 Medicine Pub Date : 2023-10-01 DOI: 10.1016/j.ijso.2023.100687
Masoud Saadat Fakhr , Fatemeh Karimi , Kiana Rezvanfar , Delyar Mardmomen , Poorya Gholami , Zahra Amini , Koosha Amiri , Mahnaz Narimani Zamanabadi

Background

Postoperative pain control is critical after abdominal surgery. primary researches suggest that vitamin D and nasal calcitonin spray may have an effect in reducing postoperative pain.

Objective

This study aims to compare postoperative abdominal pain, in patients who received a combination of Nasocalcin spray and vitamin D to those who received Nasocalcin spray.

Methods

In this double-blind randomized clinical trial, 34 patient candidates for abdominal surgery were selected. They were randomly divided into 2 groups (group A (N = 17) received vitamin D and Nasocalcin spray, and group B (N = 17) received Nasocalcin spray). The drugs have been administered to patients 1 h before surgery. Equivalent amounts of Nasocalcin and intramuscular distilled water were administered to the calcitonin group. after the surgery Patients’' pain levels were measured using a visual analog scale (VAS) after they had gained full consciousness and 6, 12, and 24 h after surgery. the amount of narcotics injected in the first 24 h after surgery was monitored and compared between the two groups.

Results

There was no significant relation between the groups in terms of age (p = 0.98), gender distribution (p = 0.1), surgery duration (p = 0.35), and pain scores after surgery (p = 0.67). In comparison to group B, at 6 h (p = 0.007), 12 h (p = 0.001), and 24 h (p = 0.003), group A reported significantly less pain. There was a significant reduction in total narcotic injected (p = 0.003) in group A.

Conclusions

Preoperative administration of vitamin D with nasal calcitonin spray improved postoperative pain control compared to nasal calcitonin. This non-opioid drug combination represents a preemptive medication for enhanced recovery after abdominal surgery.

背景腹部手术后疼痛控制至关重要。初步研究表明,维生素D和降钙素鼻喷雾剂可能对减轻术后疼痛有一定作用。目的本研究旨在比较接受Nasocalcin喷雾剂和维生素D联合治疗的患者和接受Nasocaalcin喷雾剂治疗的患者的术后腹痛。方法在这项双盲随机临床试验中,选择34名腹部手术患者。他们被随机分为2组(A组(N=17)接受维生素D和Nasocalcin喷雾剂,B组(N=17)接受Nasocalchin喷雾剂)。患者在手术前1小时服用了这些药物。降钙素组给予等量的Nasocalcin和肌内蒸馏水。术后,在患者获得完全意识后以及术后6、12和24小时,使用视觉模拟量表(VAS)测量患者的疼痛水平。监测并比较两组在术后前24小时内注射的麻醉剂量。结果两组患者的年龄(p=0.98)、性别分布(p=0.1)、手术持续时间(p=0.35)和术后疼痛评分(p=0.67)无显著相关性。与B组相比,A组在6小时(p=0.007)、12小时(p<0.001)和24小时(p>0.003)的疼痛明显减轻。a组注射的麻醉剂总量显著减少(p=0.003)。结论与鼻降钙素相比,术前用降钙素喷鼻剂给予维生素D可改善术后疼痛控制。这种非阿片类药物组合代表了一种用于增强腹部手术后恢复的先发制人的药物。
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引用次数: 0
Rising cases of contaminated liquid medicine poisoning: Recent reported cases and what we need to learn-Correspondence 不断上升的受污染药液中毒病例:最近报告的病例和我们需要了解的-函授
IF 1 Q3 Medicine Pub Date : 2023-10-01 DOI: 10.1016/j.ijso.2023.100685
Hitesh Chopra, Kavita Munjal, Vinod Kumar Gauttam, Shabana Bibi, Partha Biswas
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引用次数: 0
Three surgical cases of Situs Inversus Totalis with individual challenges; Case report and literature review 完全性倒位伴个体化挑战手术3例病例报告及文献复习
IF 1 Q3 Medicine Pub Date : 2023-10-01 DOI: 10.1016/j.ijso.2023.100689
Arash Mohammadi Tofigh, Behzad Nematihonar, Behzad Azimi, Alireza Haghbin Toutounchi, Hojatolah Khoshnoudi, Seyed Pedram Kouchak Hosseini, Mohammad Aghaei

Introduction and Importance

Situs Inversus Totalis (SIT) is a rare congenital condition resulting in the complete reversal of thoracoabdominal solid organs. Although rare, it has a higher prevalence in males with an incidence of 1:10,000. The embryonic rotation of the midgut occurs in the opposite direction, leading to a mirror-image arrangement of all visceral organs in both the thorax and abdomen. While individuals with this condition generally live without complications, its importance lies in the differences and difficulties encountered during operative procedures, particularly organ transplantations.

Case presentation

In this article we have presented 3 cases of situs inversus with different complications, admitted in a month, an 83 year-old woman with cholecystitis, a 46 year-old woman with spontaneous peritonitis caused by peptic ulcer perforation and a 26 year-old young man with volvulus of sigmoid.

Clinical Discussion

We have provided a comprehensive description of this uncommon medical condition, including its various facets and associated complications. Medical literature has been searched to find more relevant information about SITs for better optimal planning in surgery.

Conclusion

Situs Inversus Totalis can create challenges in clinical practice, particularly in surgical procedures, due to the reversal of anatomy. Although it does not inherently cause specific complications, it can complicate the diagnosis and management of certain medical conditions. Accurate imaging is crucial for diagnosis and treatment planning. Healthcare professionals must remain vigilant and adaptable when treating patients with SIT.

引言和重要意义SIT是一种罕见的先天性疾病,可导致胸腹实体器官完全逆转。虽然罕见,但它在男性中的发病率更高,发病率为1:10000。中肠的胚胎旋转方向相反,导致胸部和腹部所有内脏器官的镜像排列。虽然患有这种疾病的人通常不会出现并发症,但其重要性在于手术过程中遇到的差异和困难,尤其是器官移植。病例介绍在本文中,我们报告了3例在一个月内入院的具有不同并发症的坐位内翻,一名83岁的女性胆囊炎,一名46岁的女性消化性溃疡穿孔引起的自发性腹膜炎,以及一名26岁的年轻男性乙状结肠扭转。临床讨论我们对这种罕见的疾病进行了全面的描述,包括其各个方面和相关并发症。已经搜索了医学文献,以找到更多关于SIT的相关信息,从而在外科手术中更好地进行优化规划。结论由于解剖结构的逆转,Totalis内翻足在临床实践中,特别是在外科手术中,会带来挑战。尽管它本身不会引起特定的并发症,但它会使某些疾病的诊断和管理复杂化。准确的成像对诊断和治疗计划至关重要。医疗保健专业人员在治疗SIT患者时必须保持警惕和适应性。
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引用次数: 0
The changing landscape of scrub typhus: Implications for global public health 丛林斑疹伤寒的变化:对全球公共卫生的影响
IF 1 Q3 Medicine Pub Date : 2023-10-01 DOI: 10.1016/j.ijso.2023.100680
Sunita Kalita , Prakasini Satapathy , Pawan Kumar, Sarvesh Rustagi, Keerti Bhusan Pradhan, Zahraa Haleem Al-qaim, Aroop Mohanty, Ranjit Sah, Bijaya K. Padhi
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引用次数: 0
Twisted ovarian cyst in postmenopausal woman: A case report 绝经后妇女卵巢扭曲囊肿1例
IF 1 Q3 Medicine Pub Date : 2023-10-01 DOI: 10.1016/j.ijso.2023.100681
Brahmana Askandar Tjokroprawiro, Khoirunnisa Novitasari, Renata Alya Ulhaq

Introduction

Twisted ovarian cysts are acute conditions that cause sudden pain in the lower abdomen and may occur in older people. A twisted ovarian cyst presents as a complex cyst picture on ultrasound and CT scans and may mimic malignant ovarian masses. A normal CA-125 level in an older woman with a complex ovarian cyst who presents with acute pelvic pain may indicate a twisted ovarian cyst.

Case presentation

A 62-year-old woman presented with acute pelvic pain. A CT scan revealed a cystic ovarian mass with a diameter of 15,1 cm x 10,2 cm x 11,2 cm. Additionally, thick septations and multiple projected mural nodules were detected with normal CA-125 levels.

Discussion

The patient underwent an exploratory laparotomy. Subsequently, a midline incision was made and 100 ml of hemorrhagic ascites was observed. Macroscopic examination of the left ovary revealed an ovarian cyst with necrosis and bleeding, weighing 830 g, and measuring 15 × 12 × 8 cm. Histopathological examination of the cyst revealed serous cystadenoma.

Conclusion

This case suggests that a twisted ovarian cyst may occur in old age; therefore, in older women with complaints of sudden pain in the lower abdomen, a twisted ovarian cyst should be suspected. In post-menopausal women, ovarian masses may not be indicative of a malignancy. However, a twisted benign ovarian cyst should be considered if a complex ovarian mass with acute pelvic pain and normal CA-125 levels is found.

卵巢扭曲囊肿是引起下腹部突然疼痛的急性病,可能发生在老年人身上。扭曲卵巢囊肿在超声和CT扫描上表现为复杂的囊肿图像,可能与卵巢恶性肿块相似。有复杂卵巢囊肿的老年妇女出现急性盆腔疼痛,CA-125水平正常可能提示卵巢囊肿扭曲。病例表现:一名62岁女性表现为急性盆腔疼痛。CT扫描显示卵巢囊性肿块,直径15.1 cm × 10.2 cm × 11.2 cm。此外,在CA-125水平正常的情况下,检测到厚分隔和多个突出的壁结节。患者接受了探查性剖腹手术。随后行中线切口,见出血性腹水100 ml。左侧卵巢肉眼检查发现卵巢囊肿坏死出血,重830g,尺寸15 × 12 × 8cm。囊肿的组织病理学检查显示浆液性囊腺瘤。结论本病例提示卵巢扭曲囊肿可能发生在老年;因此,当老年妇女主诉下腹部突然疼痛时,应怀疑卵巢囊肿扭曲。在绝经后妇女,卵巢肿块可能不是恶性肿瘤的指示。然而,如果发现复杂的卵巢肿块伴急性盆腔疼痛且CA-125水平正常,则应考虑扭曲的良性卵巢囊肿。
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引用次数: 0
Japanese encephalitis: An indian perspective 日本脑炎:印度人的观点
IF 1 Q3 Medicine Pub Date : 2023-09-01 DOI: 10.1016/j.ijso.2023.100673
Kamran Zaman, Shailendra Yadav, Rachana Mehta, Ranjana Rohilla, Aroop Mohanty, Ranjit Sah
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引用次数: 0
Nanoencapsulated bioinks: The silver lining to safe tattoos and laser-assisted tattoo removal 纳米生物墨水:安全纹身和激光辅助纹身去除的一线希望
IF 1 Q3 Medicine Pub Date : 2023-09-01 DOI: 10.1016/j.ijso.2023.100672
ArunSundar MohanaSundaram , Yashoda Pokharel, Dionisio Lorenzo Lorenzo-Villegas, Md Ariful Haque, Md Aminul Islam
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引用次数: 0
Laparoscopic subtotal cholecystectomy by linear stapler: A simple and feasible technique for difficult cases with severe cholecystitis. A case series 直线缝合器腹腔镜胆囊大部切除术:一种简单可行的治疗重症胆囊炎疑难病例的技术。案例系列
IF 1 Q3 Medicine Pub Date : 2023-09-01 DOI: 10.1016/j.ijso.2023.100671
Keisuke Noda, Tamotsu Kuroki

Introduction

Laparoscopic subtotal cholecystectomy (LSC) is recognized as a safe, feasible alternative method for avoiding common bile duct injuries in 'difficult' gallbladders. We describe the details of an LSC technique that uses a linear stapler with the reconstituting method for severe cholecystitis.

Methods

We retrospectively analyzed the cases of 19 Japanese patients diagnosed with acute cholecystitis who underwent LSC (Jan. 2017–Dec. 2020). In each patient, we first attempted to perform a standard laparoscopic cholecystectomy. Four trocars were inserted in all patients. When it was extremely difficult to expose and dissect the triangle of Calot or the neck of the gallbladder due to severe inflammation and fibrosis, an LSC was performed. The gallbladder was divided downward from the gallbladder fundus to the neck. We opened the gallbladder wall at the fundus and removed all gallstones with suction and saline flushing. The gallbladder was transected by a laparoscopic linear stapler.

Results

The median operation time was 166 min; intraoperative blood loss was 35 mL. One patient (5.3%) had minor bile leakage that promptly resolved after the transpapillary approach. The median postoperative hospital stay was 7 days.

Conclusion

Using a linear stapler to divide the gallbladder neck is a simple, feasible strategy for LSCs in difficult gallbladders.

腹腔镜胆囊次全切除术(LSC)被认为是一种安全、可行的替代方法,可避免“困难”胆囊的胆总管损伤。我们描述了一个LSC技术的细节,使用线性订书机与重建方法严重胆囊炎。方法回顾性分析日本19例急性胆囊炎患者(2017年1月- 12月)行LSC的病例。2020)。在每个病人中,我们首先尝试进行标准的腹腔镜胆囊切除术。所有患者均置入4个套管针。当由于严重的炎症和纤维化,难以暴露和解剖Calot三角或胆囊颈部时,进行了LSC手术。胆囊从胆囊底向下切开至颈部。我们在底部打开胆囊壁,用抽吸和生理盐水冲洗取出所有胆结石。用腹腔镜线性吻合器切开胆囊。结果手术中位时间为166 min;术中出血量为35 mL。1例(5.3%)患者有轻微胆漏,经经乳头入路后立即消失。术后平均住院时间为7天。结论采用线性吻合器分割胆囊颈是一种简单可行的方法。
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引用次数: 0
FDA approves first leadless dual-chamber pacing system; A breakthrough in therapy of bradycardia FDA批准首个无引线双腔起搏系统;治疗心动过缓的突破
IF 1 Q3 Medicine Pub Date : 2023-09-01 DOI: 10.1016/j.ijso.2023.100660
Eman Ali

More than 700,000 pacemakers (PMs) are implanted worldwide each year, with more than 250,000 deployed in the United States. Leadless cardiac pacemakers (LPCs) are an alternative to conventional pacemakers because they do not require permanent transvenous leads while alleviating bradyarrhythmias. An innovation in the field of pacing systems called ‘dual chamber pacing system’ has received US Food and Drug Administration (FDA) approval which is a safe, non-invasive, and efficacious procedure as documented by a landmark clinical study. It succeeded in its pre-established safety and performance goals, with definite procedural success, atrial pacing and reliable atrioventricular (AV) synchrony. Despite its hailing success, the system continues to undergo transformation and development, and requires further longitudinal data to reaffirm its safety and efficacy.

全球每年植入的起搏器超过70万个,其中超过25万个部署在美国。无导线心脏起搏器(LPC)是传统起搏器的替代品,因为它们在缓解缓慢性心律失常的同时不需要永久性经静脉导线。起搏系统领域的一项创新,称为“双腔起搏系统”,已获得美国食品药品监督管理局(FDA)的批准,这是一项具有里程碑意义的临床研究所记录的安全、无创和有效的程序。它成功地实现了预先设定的安全和性能目标,具有明确的手术成功、心房起搏和可靠的房室(AV)同步性。尽管该系统取得了可喜的成功,但它仍在继续转型和发展,需要进一步的纵向数据来重申其安全性和有效性。
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引用次数: 0
The management of torsion of huge pedunculated fibroid in 19 weeks pregnant in a low-income country, a case report 低收入国家19周妊娠巨大带蒂肌瘤扭转的处理1例
IF 1 Q3 Medicine Pub Date : 2023-09-01 DOI: 10.1016/j.ijso.2023.100676
Kenana Tawashi , Yamama Tawashi , Sami Jomaa , Eyad Alabdallah , Mustafa Al-Hussien , Ameen Ammar

Introduction and importance

Fibroids are common benign neoplasms of the uterus, exciting in >70% of women. Also, in 0.3–15% of pregnant. They are classified into submucosal, intramural, and subserosal. The diagnosis depends on ultrasound imaging, while the treatment depends on surveillance, drugs, and surgery.

Case presentation

A 43-year-old nulligravida at 19 weeks’ gestation complained of increased unresponsive subacute pain that started for 3 weeks. She was apprehensive and pale and had digestive disturbances. The physical examination showed tenderness, and the size of the uterus was equivalent to 36 weeks. The radiological investigations showed a live fetus and a well-defined subserosal fibroid measuring 20 × 19 cm, connected to the uterus by a peduncle with torsion signs on echo-Doppler. A myomectomy was done and we had good outcomes for both the mother and fetus.

Clinical discussion

Many factors get together and make our case extraordinary; the rapid increase in size, the size of the fibroid, the pregnancy, the torsion, and the lack of equipment in our area that forced us to treat the patient urgently by laparotomy, which had risks on both the mother and the fetus.

Conclusion

This case highlights that even though laparoscopy is the best choice to treat fibroids during pregnancy; laparotomy is a good choice and has good outcomes for both the mother and the fetus in low-income countries. In addition, Fast diagnosis and treatment also are important to get the best results, especially in complicated situations.

子宫肌瘤是一种常见的子宫良性肿瘤,在70%的女性中存在。此外,在0.3-15%的孕妇。它们分为粘膜下、壁内和浆膜下。诊断依赖于超声成像,而治疗依赖于监测、药物和手术。病例介绍一例43岁妊娠19周无孕妇女主诉亚急性无反应性疼痛加重,持续3周。她焦虑不安,脸色苍白,有消化障碍。查体见压痛,子宫大小相当于36周。影像学检查显示胎儿活,膜下肌瘤轮廓清晰,大小为20 × 19厘米,通过超声多普勒显示扭转征的子宫蒂与子宫相连。我们做了子宫肌瘤切除术,对母亲和胎儿都有很好的结果。临床讨论多种因素综合在一起,使我们的病例与众不同;子宫肌瘤的迅速增大,子宫肌瘤的大小,妊娠,扭转,以及我们所在地区设备的缺乏,迫使我们紧急对患者进行剖腹手术,这对母亲和胎儿都有风险。结论本病例提示尽管腹腔镜是治疗妊娠期肌瘤的最佳选择;在低收入国家,剖腹手术是一种很好的选择,对母亲和胎儿都有很好的结局。此外,快速诊断和治疗对于获得最佳结果也很重要,特别是在复杂的情况下。
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引用次数: 0
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International Journal of Surgery Open
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