首页 > 最新文献

Journal of Mind and Medical Sciences最新文献

英文 中文
Dental fear, anxiety, and phobia; causes, diagnostic criteria and the medical and social impact 牙科恐惧、焦虑和恐惧症;病因、诊断标准以及医疗和社会影响
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-10-23 DOI: 10.22543/2392-7674.1348
N. Avramova
Despite technological advances in modern medical science and practice, many people still associate dental treatment with unpleasant emotional sensations and pain. According to the current literature, dental fear and anxiety are psychological barriers that negatively affect frequency of patient attendance which results in avoidant behavior and poorer oral health-related quality of life. This paper was therefore aimed at discussing basic theoretical aspects concerning diagnostic criteria, causes, and impacts of dental fear, anxiety, and phobia. Clarifying their differential diagnostic characteristics, clinical features and specific causes may play an important role in proper diagnosing, positive influencing, and management of this group of patients, thus providing the opportunity for increasing quality of dental healthcare services as well as improving patient’s dental health and self-perceived quality of life
尽管现代医学和实践的技术进步,许多人仍然将牙科治疗与不愉快的情绪和疼痛联系在一起。根据目前的文献,牙科恐惧和焦虑是一种心理障碍,会对患者就诊频率产生负面影响,从而导致回避型行为和口腔健康相关生活质量较差。因此,本文旨在讨论有关牙科恐惧、焦虑和恐惧症的诊断标准、原因和影响的基本理论方面。阐明其鉴别诊断特征、临床特征和具体原因可能在正确诊断、积极影响和管理这类患者方面发挥重要作用,从而为提高牙科保健服务质量以及改善患者的牙科健康和自我感知的生活质量提供机会
{"title":"Dental fear, anxiety, and phobia; causes, diagnostic criteria and the medical and social impact","authors":"N. Avramova","doi":"10.22543/2392-7674.1348","DOIUrl":"https://doi.org/10.22543/2392-7674.1348","url":null,"abstract":"Despite technological advances in modern medical science and practice, many people still associate dental treatment with unpleasant emotional sensations and pain. According to the current literature, dental fear and anxiety are psychological barriers that negatively affect frequency of patient attendance which results in avoidant behavior and poorer oral health-related quality of life. This paper was therefore aimed at discussing basic theoretical aspects concerning diagnostic criteria, causes, and impacts of dental fear, anxiety, and phobia. Clarifying their differential diagnostic characteristics, clinical features and specific causes may play an important role in proper diagnosing, positive influencing, and management of this group of patients, thus providing the opportunity for increasing quality of dental healthcare services as well as improving patient’s dental health and self-perceived quality of life","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":"1 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41814955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
SARS-CoV-2 Omicron (B.1.1.529) variant: structural features, biological characteristics, impact on scientific research, general precautions and protective procedures; a systematic review SARS-CoV-2 Omicron (B.1.1.529)变体:结构特征、生物学特性、对科学研究的影响、一般预防措施和保护程序;系统回顾
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-10-23 DOI: 10.22543/2392-7674.1343
P. Nagarajan, Anitha Vetrivel, J. Kumar, A. Howlader, K. Rangarajalu, Satheesh Kumar Sabapathy, Muthu Gopal, Saravanaavel Kumar
The SARS-CoV-2 mutations that have occurred have alarmed the entire medical community. Thus, global concerns have been expressed regarding the transmission, pathogenicity and immune evasion of the Omicron strain, which shares mutations with the variants of concern Alpha, Beta, and Gamma strains. Still, Omicron transmission has crossed numerous borders worldwide compared to other types of SARS-CoV-2. The number of confirmed cases has increased and is reappearing in India. Given the worrisome situation created by the Omicron outbreak, scientists and postgraduates have had to make decisions about current research programs at institutions around the globe. The Omicron variants under development have significantly heightened worldwide pandemic concerns. In this review, the authors will outline the molecular features and efficacy of vaccination, highlight possible omicron impacts on scientific research, and provide precautions, procedural guidelines for organizing scientific meetings during a pandemic.
严重急性呼吸系统综合征冠状病毒2型的突变已经引起了整个医学界的警觉。因此,全球对奥密克戎毒株的传播、致病性和免疫逃避表示担忧,该毒株与变异毒株阿尔法、贝塔和伽马毒株有共同突变。尽管如此,与其他类型的严重急性呼吸系统综合征冠状病毒2型相比,奥密克戎在全球范围内的传播已经跨越了许多边界。印度的确诊病例数量有所增加,并再次出现。鉴于奥密克戎疫情造成的令人担忧的局面,科学家和研究生不得不就全球各机构目前的研究项目做出决定。正在研发的奥密克戎变异株大大加剧了全球对疫情的担忧。在这篇综述中,作者将概述疫苗接种的分子特征和疗效,强调奥密克戎对科学研究的可能影响,并为在大流行期间组织科学会议提供预防措施和程序指南。
{"title":"SARS-CoV-2 Omicron (B.1.1.529) variant: structural features, biological characteristics, impact on scientific research, general precautions and protective procedures; a systematic review","authors":"P. Nagarajan, Anitha Vetrivel, J. Kumar, A. Howlader, K. Rangarajalu, Satheesh Kumar Sabapathy, Muthu Gopal, Saravanaavel Kumar","doi":"10.22543/2392-7674.1343","DOIUrl":"https://doi.org/10.22543/2392-7674.1343","url":null,"abstract":"The SARS-CoV-2 mutations that have occurred have alarmed the entire medical community. Thus, global concerns have been expressed regarding the transmission, pathogenicity and immune evasion of the Omicron strain, which shares mutations with the variants of concern Alpha, Beta, and Gamma strains. Still, Omicron transmission has crossed numerous borders worldwide compared to other types of SARS-CoV-2. The number of confirmed cases has increased and is reappearing in India. Given the worrisome situation created by the Omicron outbreak, scientists and postgraduates have had to make decisions about current research programs at institutions around the globe. The Omicron variants under development have significantly heightened worldwide pandemic concerns. In this review, the authors will outline the molecular features and efficacy of vaccination, highlight possible omicron impacts on scientific research, and provide precautions, procedural guidelines for organizing scientific meetings during a pandemic.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43198507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Limb amputations; etiopathogenesis, diagnosis and the multidisciplinary therapeutic approach 截肢;病因、诊断和多学科治疗方法
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-10-23 DOI: 10.22543/2392-7674.1361
V. Constantin, B. Socea, B. Gaspar, D. Epistatu, I. Păunică, A. Dumitriu, S. Păunică, A. Silaghi
Despite remarkable advances in medicine, limb amputations remain a therapeutic measure that saves the lives of many patients. Given the varied etiopathogenesis, such operations are performed both as an emergency and as an elective procedure. Such interventions address either only the distal segments of a limb
尽管医学取得了显著进步,但截肢仍然是挽救许多患者生命的治疗措施。考虑到病因的多样性,这种手术既是紧急手术,也是选择性手术。这种干预措施要么只针对肢体的远端
{"title":"Limb amputations; etiopathogenesis, diagnosis and the multidisciplinary therapeutic approach","authors":"V. Constantin, B. Socea, B. Gaspar, D. Epistatu, I. Păunică, A. Dumitriu, S. Păunică, A. Silaghi","doi":"10.22543/2392-7674.1361","DOIUrl":"https://doi.org/10.22543/2392-7674.1361","url":null,"abstract":"Despite remarkable advances in medicine, limb amputations remain a therapeutic measure that saves the lives of many patients. Given the varied etiopathogenesis, such operations are performed both as an emergency and as an elective procedure. Such interventions address either only the distal segments of a limb","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44418208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Eating Disorders in Men: A Comprehensive Summary 男性饮食失调:综合综述
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-10-23 DOI: 10.22543/2392-7674.1362
Connor James Spratt, Liam Alexander MacKenzie Myles, E. Merlo
Eating disorders (EDs) have detrimental effects on an individual’s physical and mental health, along with significant interpersonal, social and economic effects. Furthermore, men who are suffering with an ED face unique challenges with this. Men suffering with EDs have historically received little attention within ED research, diagnosis and intervention. However, the number of men suffering with these issues is significant and growing. Understanding of EDs tend to ignore male experiences, meaning many are left to suffer in silence until the ED has developed to a critical point. However, many now recognize the need to understand the issues facing men suffering with an ED. By improving our understanding, we can better improve early detection, diagnosis and treatment for those who are suffering. This paper aims to provide a comprehensive general introduction to this growing area of research and it is hoped that it will be of good use to interested researchers, students and the general public. Prevalence, presentation, history, diagnosis and more will be covered in order to provide a well-rounded understanding of EDs in men.
饮食失调(EDs)对个人的身心健康有不利影响,并对人际、社会和经济产生重大影响。此外,患有ED的男性面临着独特的挑战。男性ED患者历来很少受到ED研究、诊断和干预的关注。然而,患有这些问题的男性数量显著增加。对ED的理解往往忽略了男性的经历,这意味着许多人只能默默忍受,直到ED发展到一个临界点。然而,许多人现在认识到有必要了解男性ED患者面临的问题。通过提高我们的理解,我们可以更好地改善患者的早期发现、诊断和治疗。本文旨在全面介绍这一不断发展的研究领域,希望对感兴趣的研究人员、学生和公众有所帮助。患病率、表现、病史、诊断等内容将被涵盖,以提供对男性ed的全面了解。
{"title":"Eating Disorders in Men: A Comprehensive Summary","authors":"Connor James Spratt, Liam Alexander MacKenzie Myles, E. Merlo","doi":"10.22543/2392-7674.1362","DOIUrl":"https://doi.org/10.22543/2392-7674.1362","url":null,"abstract":"Eating disorders (EDs) have detrimental effects on an individual’s physical and mental health, along with significant interpersonal, social and economic effects. Furthermore, men who are suffering with an ED face unique challenges with this. Men suffering with EDs have historically received little attention within ED research, diagnosis and intervention. However, the number of men suffering with these issues is significant and growing. Understanding of EDs tend to ignore male experiences, meaning many are left to suffer in silence until the ED has developed to a critical point. However, many now recognize the need to understand the issues facing men suffering with an ED. By improving our understanding, we can better improve early detection, diagnosis and treatment for those who are suffering. This paper aims to provide a comprehensive general introduction to this growing area of research and it is hoped that it will be of good use to interested researchers, students and the general public. Prevalence, presentation, history, diagnosis and more will be covered in order to provide a well-rounded understanding of EDs in men.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43668459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Management of systemic lupus erythematosus in pregnancy 妊娠期系统性红斑狼疮的处理
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-10-23 DOI: 10.22543/2392-7674.1358
O. Bălălău, M. Loghin, D. Bogheanu, N. Bacalbaşa, A. Stănescu, D. Balan, I. Păunică, O. Olaru
Systemic lupus erythematosus is one of the most common autoimmune disorders affecting young women. Pregnant women with lupus are generally at higher risk for certain pregnancy complications than women without comorbidities. Even so, a pregnancy with lupus can be carried to term in optimal conditions if it is properly managed by a doctor. Monitoring is generally recommended six months after the onset of lupus symptoms, and ideally there should be no active lupus symptoms prior to conception. General screening tests should include the anti-phospholipid, anti-Ro and anti-La antibodies. Women who are positive for these antibodies have an increased risk of congenital heart block in the fetus. In addition, pregnant women with lupus have an increased risk of spontaneous abortion, intrauterine fetal growth restriction, pre-term birth, while neonatal lupus syndrome is a major fetal condition. The maternal risks are faced with disease flares, pre-eclampsia and other complications. Treatment options during pregnancy are limited to a few safe medications. For example, prednisone is unlikely to cause fetal malformations, but it increases the risk of diabetes and high blood pressure in the mother. Consequently, a careful multidisciplinary monitoring is essential for optimal results in pregnancy with lupus.
系统性红斑狼疮是影响年轻女性的最常见的自身免疫性疾病之一。患有狼疮的孕妇通常比没有合并症的孕妇患某些妊娠并发症的风险更高。即便如此,如果医生处理得当,患有狼疮的妊娠期可以在最佳条件下足月。通常建议在狼疮症状发作六个月后进行监测,理想情况下,在受孕前不应出现活动性狼疮症状。一般筛选测试应包括抗磷脂、抗Ro和抗La抗体。这些抗体呈阳性的女性胎儿患先天性心脏传导阻滞的风险增加。此外,患有狼疮的孕妇自然流产、胎儿宫内生长受限、早产的风险增加,而新生儿狼疮综合征是一种主要的胎儿疾病。产妇面临疾病发作、先兆子痫和其他并发症的风险。怀孕期间的治疗选择仅限于一些安全的药物。例如,泼尼松不太可能导致胎儿畸形,但它会增加母亲患糖尿病和高血压的风险。因此,仔细的多学科监测对于狼疮妊娠期的最佳结果至关重要。
{"title":"Management of systemic lupus erythematosus in pregnancy","authors":"O. Bălălău, M. Loghin, D. Bogheanu, N. Bacalbaşa, A. Stănescu, D. Balan, I. Păunică, O. Olaru","doi":"10.22543/2392-7674.1358","DOIUrl":"https://doi.org/10.22543/2392-7674.1358","url":null,"abstract":"Systemic lupus erythematosus is one of the most common autoimmune disorders affecting young women. Pregnant women with lupus are generally at higher risk for certain pregnancy complications than women without comorbidities. Even so, a pregnancy with lupus can be carried to term in optimal conditions if it is properly managed by a doctor. Monitoring is generally recommended six months after the onset of lupus symptoms, and ideally there should be no active lupus symptoms prior to conception. General screening tests should include the anti-phospholipid, anti-Ro and anti-La antibodies. Women who are positive for these antibodies have an increased risk of congenital heart block in the fetus. In addition, pregnant women with lupus have an increased risk of spontaneous abortion, intrauterine fetal growth restriction, pre-term birth, while neonatal lupus syndrome is a major fetal condition. The maternal risks are faced with disease flares, pre-eclampsia and other complications. Treatment options during pregnancy are limited to a few safe medications. For example, prednisone is unlikely to cause fetal malformations, but it increases the risk of diabetes and high blood pressure in the mother. Consequently, a careful multidisciplinary monitoring is essential for optimal results in pregnancy with lupus.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48051022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The benign mimickers of carcinoma on breast MRI 乳腺MRI良性模拟癌
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-04-10 DOI: 10.22543/7674.91.p96101
I. Durur-Subasi, A. Karaman, E. Demirci, S. Sipal, M. Akçay
The similarity between benign and malignant pathologies on magnetic resonance imaging (MRI) and a wide-ranging variability of the lesions from benign proliferative changes to invasive breast carcinoma cause a lower and wide-ranging specificity of breast MRI relative to its surpass sensitivity. A wide range of tissue components such as the skin, the adipose tissue, vascular and neural tissues, connective tissues, glandular tissues, ducts, and muscle tissues are found here all together. This pictorial review was aimed at deliberating benign mimickers of breast carcinoma on MRI and trying to call attention to the overlapping and distinctive features.
磁共振成像(MRI)良性和恶性病理的相似性,以及从良性增生性改变到浸润性乳腺癌病变的广泛变异性,导致乳腺MRI相对于其超敏感性而言特异性较低且范围较广。广泛的组织成分,如皮肤、脂肪组织、血管和神经组织、结缔组织、腺体组织、导管和肌肉组织都在这里发现。这篇图片综述的目的是在MRI上讨论乳腺癌的良性模仿者,并试图引起人们对重叠和独特特征的注意。
{"title":"The benign mimickers of carcinoma on breast MRI","authors":"I. Durur-Subasi, A. Karaman, E. Demirci, S. Sipal, M. Akçay","doi":"10.22543/7674.91.p96101","DOIUrl":"https://doi.org/10.22543/7674.91.p96101","url":null,"abstract":"The similarity between benign and malignant pathologies on magnetic resonance imaging (MRI) and a wide-ranging variability of the lesions from benign proliferative changes to invasive breast carcinoma cause a lower and wide-ranging specificity of breast MRI relative to its surpass sensitivity. A wide range of tissue components such as the skin, the adipose tissue, vascular and neural tissues, connective tissues, glandular tissues, ducts, and muscle tissues are found here all together. This pictorial review was aimed at deliberating benign mimickers of breast carcinoma on MRI and trying to call attention to the overlapping and distinctive features.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2022-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45116519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The involvement of oxidative stress in non-Hodgkin’s lymphomas; a review of the literature 氧化应激在非霍奇金淋巴瘤中的作用;文献综述
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-04-10 DOI: 10.22543/7674.91.p115
R. Corbeanu, A. Gaman
Non-Hodgkin’s malignant lymphomas are a heterogeneous group of hematological malignancies, characterized by a variety of clinical, morphological, histopathological, immuno-histochemical, molecular and evolutionary features. They represent a form of cancer that develops from the lymphatic tissue, as a result of the malignant transformation of B (85%) or T (15%) lymphocytes. Lymphomagenesis is described as a multi-stage process involving the mutation and proliferation of cell clones. Oxidative stress is defined as an imbalance of cellular redox status caused by the production of reactive oxygen species (ROS) and/ or by decreasing antioxidant systems that allows their accumulation in the cell. Small quantities of ROS are involved in physiological mechanisms such as cell growth and differentiation, cell signaling, antimicrobial defense, phagocytosis. Normally, cells are capable of defending themselves against ROS damage through various scavenger systems. On the other hand, excessive ROS contribute to various diseases such as carcinogenesis, ischemia, atherosclerosis, neurodegenerative diseases. Oxidative stress exerts noxious effects on the cell structures by inducing structural changes in membranes, lipids, proteins or DNA. The present review summarizes the latest findings in understanding the ROS-linked signaling pathways in the initiation of lymphomagenesis, disease progression, metastasis, as well as in the pharmacodynamics of specific treatments for this malignancy.
非霍奇金恶性淋巴瘤是一组异质性血液系统恶性肿瘤,具有多种临床、形态学、组织病理学、免疫组织化学、分子和进化特征。它们代表了一种癌症,由淋巴组织发展而来,是B(85%)或T(15%)淋巴细胞恶性转化的结果。淋巴瘤发生被描述为涉及细胞克隆的突变和增殖的多阶段过程。氧化应激被定义为由活性氧(ROS)的产生和/或允许其在细胞中积累的抗氧化系统减少引起的细胞氧化还原状态失衡。少量ROS参与细胞生长和分化、细胞信号传导、抗菌防御、吞噬作用等生理机制。通常,细胞能够通过各种清除剂系统保护自己免受ROS损伤。另一方面,过量的ROS会导致各种疾病,如致癌、缺血、动脉粥样硬化、神经退行性疾病。氧化应激通过诱导细胞膜、脂质、蛋白质或DNA的结构变化,对细胞结构产生有害影响。本综述总结了在理解ROS相关信号通路在淋巴结转移、疾病进展、转移的起始以及这种恶性肿瘤的特异性治疗的药效学方面的最新发现。
{"title":"The involvement of oxidative stress in non-Hodgkin’s lymphomas; a review of the literature","authors":"R. Corbeanu, A. Gaman","doi":"10.22543/7674.91.p115","DOIUrl":"https://doi.org/10.22543/7674.91.p115","url":null,"abstract":"Non-Hodgkin’s malignant lymphomas are a heterogeneous group of hematological malignancies, characterized by a variety of clinical, morphological, histopathological, immuno-histochemical, molecular and evolutionary features. They represent a form of cancer that develops from the lymphatic tissue, as a result of the malignant transformation of B (85%) or T (15%) lymphocytes. Lymphomagenesis is described as a multi-stage process involving the mutation and proliferation of cell clones. Oxidative stress is defined as an imbalance of cellular redox status caused by the production of reactive oxygen species (ROS) and/ or by decreasing antioxidant systems that allows their accumulation in the cell. Small quantities of ROS are involved in physiological mechanisms such as cell growth and differentiation, cell signaling, antimicrobial defense, phagocytosis. Normally, cells are capable of defending themselves against ROS damage through various scavenger systems. On the other hand, excessive ROS contribute to various diseases such as carcinogenesis, ischemia, atherosclerosis, neurodegenerative diseases. Oxidative stress exerts noxious effects on the cell structures by inducing structural changes in membranes, lipids, proteins or DNA. The present review summarizes the latest findings in understanding the ROS-linked signaling pathways in the initiation of lymphomagenesis, disease progression, metastasis, as well as in the pharmacodynamics of specific treatments for this malignancy.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2022-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45329697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Laparoscopic versus open surgical treatment of umbilical hernia 腹腔镜与开腹治疗脐疝
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-04-10 DOI: 10.22543/7674.91.p143151
A. Moisin, Mihai Faur, C. Popa, C. Gherman, V. Dumitrescu, D. Tănăsescu, A. Boicean, S. Balasescu, M. Comandasu, D. Dumitrescu, A. Zgura, C. Mohor
Umbilical hernia is one of the types of ventral hernias of the abdominal wall and it represents the externalization of a part of the abdominal contents through a defect of the anterior abdominal wall located in the umbilical region. It is estimated that more than 20 million abdominal wall hernia surgeries are performed worldwide each year. The paper presents a retrospective study on the patients diagnosed with umbilical hernia and admitted to the First and Second Surgery Departments of the Sibiu County Emergency Clinical Hospital. The study includes 82 cases diagnosed with umbilical hernias over a period of 4 years, between 01.01.2017 and 31.12.2020. Open and laparoscopic surgical techniques are compared in terms of outcomes and postoperative complications. Most cases of umbilical hernia were within the age group 51-70 years, with a slightly higher incidence in males. Arterial hypertension and obesity were the most frequent comorbidities. The alloplastic, classic or laparoscopic procedure became the most widely used due to benefits such as: rapid socio-professional reintegration, short-term hospitalization and low incidence of relapses and postoperative complications. The current trend is for the IPOM laparoscopic procedure to become the gold standard in the treatment of umbilical hernias.
脐疝是腹壁腹疝的一种,它代表着腹部内容物的一部分通过位于脐区的前腹壁缺陷外化。据估计,全世界每年进行的腹壁疝手术超过2000万次。本文对泗水县急诊临床医院一、二外科收治的脐疝患者进行了回顾性研究。该研究包括在2017年1月1日至2020年12月31日的4年内诊断为脐疝的82例病例。在结果和术后并发症方面比较了开放式和腹腔镜手术技术。大多数脐疝病例发生在51-70岁的年龄组,男性的发病率略高。动脉性高血压和肥胖是最常见的合并症。异体整形、经典或腹腔镜手术因其优点而成为最广泛使用的手术,如:快速重返社会、短期住院、复发和术后并发症发生率低。目前的趋势是IPOM腹腔镜手术成为治疗脐疝的黄金标准。
{"title":"Laparoscopic versus open surgical treatment of umbilical hernia","authors":"A. Moisin, Mihai Faur, C. Popa, C. Gherman, V. Dumitrescu, D. Tănăsescu, A. Boicean, S. Balasescu, M. Comandasu, D. Dumitrescu, A. Zgura, C. Mohor","doi":"10.22543/7674.91.p143151","DOIUrl":"https://doi.org/10.22543/7674.91.p143151","url":null,"abstract":"Umbilical hernia is one of the types of ventral hernias of the abdominal wall and it represents the externalization of a part of the abdominal contents through a defect of the anterior abdominal wall located in the umbilical region. It is estimated that more than 20 million abdominal wall hernia surgeries are performed worldwide each year. The paper presents a retrospective study on the patients diagnosed with umbilical hernia and admitted to the First and Second Surgery Departments of the Sibiu County Emergency Clinical Hospital. The study includes 82 cases diagnosed with umbilical hernias over a period of 4 years, between 01.01.2017 and 31.12.2020. Open and laparoscopic surgical techniques are compared in terms of outcomes and postoperative complications. Most cases of umbilical hernia were within the age group 51-70 years, with a slightly higher incidence in males. Arterial hypertension and obesity were the most frequent comorbidities. The alloplastic, classic or laparoscopic procedure became the most widely used due to benefits such as: rapid socio-professional reintegration, short-term hospitalization and low incidence of relapses and postoperative complications. The current trend is for the IPOM laparoscopic procedure to become the gold standard in the treatment of umbilical hernias.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2022-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48720640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Asymptomatic jejunal metastatic melanoma. A case report of anemia of uncertain origin 无症状空肠转移性黑色素瘤。不明原因贫血1例报告
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-04-10 DOI: 10.22543/7674.91.p187192
C. Nitipir, A. Paroșanu, Cristina Orlov-Slavu, Cătălin Pîrîianu, R. Vrabie, I. Slavu, V. Calu
Gastrointestinal metastases from cutaneous melanoma are rare and usually asymptomatic, with most patients not being clinically diagnosed throughout their lifetime. We report a case of how melanoma may metastasize insidiously in the small bowel. Unexplained iron deficiency anemia was assumed to be the result of underlying gastrointestinal bleeding. Therefore, the diagnosis of jejunal metastasis from cutaneous melanoma was suggested based on imaging findings and made through the histopathological examination. According to the international guidelines, the patient underwent the complete excision of the primary tumor and therapeutic lymph node dissection. Furthermore, an adjuvant treatment was required to reduce the risk of recurrence. Both immunotherapy and surgical therapy have been shown to be effective, providing long-term survival in this case.
皮肤黑色素瘤的胃肠道转移是罕见的,通常没有症状,大多数患者一生都没有临床诊断。我们报告了一例黑色素瘤如何在小肠内隐性转移的病例。不明原因的缺铁性贫血被认为是潜在的胃肠道出血的结果。因此,建议根据影像学表现并通过组织病理学检查来诊断皮肤黑色素瘤的空肠转移。根据国际指南,患者接受了原发肿瘤的完全切除和治疗性淋巴结清扫。此外,还需要辅助治疗以降低复发风险。免疫疗法和手术治疗都被证明是有效的,在这种情况下可以提供长期生存。
{"title":"Asymptomatic jejunal metastatic melanoma. A case report of anemia of uncertain origin","authors":"C. Nitipir, A. Paroșanu, Cristina Orlov-Slavu, Cătălin Pîrîianu, R. Vrabie, I. Slavu, V. Calu","doi":"10.22543/7674.91.p187192","DOIUrl":"https://doi.org/10.22543/7674.91.p187192","url":null,"abstract":"Gastrointestinal metastases from cutaneous melanoma are rare and usually asymptomatic, with most patients not being clinically diagnosed throughout their lifetime. We report a case of how melanoma may metastasize insidiously in the small bowel. Unexplained iron deficiency anemia was assumed to be the result of underlying gastrointestinal bleeding. Therefore, the diagnosis of jejunal metastasis from cutaneous melanoma was suggested based on imaging findings and made through the histopathological examination. According to the international guidelines, the patient underwent the complete excision of the primary tumor and therapeutic lymph node dissection. Furthermore, an adjuvant treatment was required to reduce the risk of recurrence. Both immunotherapy and surgical therapy have been shown to be effective, providing long-term survival in this case.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2022-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42830790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum to: Teachers’ Views on Preparation for Employment of Young Autistic People 《教师对自闭症青少年就业准备的看法》的勘误
IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-04-10 DOI: 10.22543/7674.91.p201201
Biranavan Thavapalan, E. Merlo
Background. Contemporary literature indicates that there is significant support and assistance provided by schools for young autistic people, with a positive impact on the accessibility of jobs. Nevertheless, the employment rate of autistic people is unacceptably low in the UK. The current study investigated teachers’ views on the preparation for employment of young autistic people in the UK. Methods. Interviews were conducted with individuals from the educational field and thematic analysis was used to explore the teachers’ views regarding the factors that could have an impact on the preparation for employment of young autistic people. Results. Four main themes emerged from the analysis of this study. These themes included awareness, funding and government support, action plans and motivation. Conclusion. The results obtained appear to have critical implications for the educational field and future research, being presented in this paper.
背景。当代文献表明,学校为青少年自闭症患者提供了显著的支持和帮助,对就业的可及性有积极的影响。然而,在英国,自闭症患者的就业率低得令人无法接受。目前的研究调查了英国教师对年轻自闭症患者就业准备的看法。方法。对教育界人士进行访谈,并采用专题分析探讨教师对影响自闭症青少年就业准备的因素的看法。结果。对这项研究的分析产生了四个主要主题。这些主题包括认识、资金和政府支持、行动计划和动机。结论。本文所获得的结果似乎对教育领域和未来的研究具有重要意义。
{"title":"Erratum to: Teachers’ Views on Preparation for Employment of Young Autistic People","authors":"Biranavan Thavapalan, E. Merlo","doi":"10.22543/7674.91.p201201","DOIUrl":"https://doi.org/10.22543/7674.91.p201201","url":null,"abstract":"Background. Contemporary literature indicates that there is significant support and assistance provided by schools for young autistic people, with a positive impact on the accessibility of jobs. Nevertheless, the employment rate of autistic people is unacceptably low in the UK. The current study investigated teachers’ views on the preparation for employment of young autistic people in the UK. Methods. Interviews were conducted with individuals from the educational field and thematic analysis was used to explore the teachers’ views regarding the factors that could have an impact on the preparation for employment of young autistic people. Results. Four main themes emerged from the analysis of this study. These themes included awareness, funding and government support, action plans and motivation. Conclusion. The results obtained appear to have critical implications for the educational field and future research, being presented in this paper.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2022-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42392248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Mind and Medical Sciences
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1