Ioana Duca, F. Mihaileanu, A. Chira, R. Chira, Teodora Surdea Blaga, Diana Popovici, Adriana Albu, D. Dumitrascu
Inflammatory fibroid polyps are very rare gastrointestinal tumors. We present the case of a 66-year-old woman with severe anemia and a giant gastric polyp which had intermittent duodenal intussusception. Ultrasonography showed increased gastric wall thickness and suspected an ampulloma, as revealed also by endoscopy and computed tomography. Ultrasonography reassessment showed later the intragastric mass, which was confirmed by endosonography: giant pediculated hypervascular polyp suggesting malignancy. Challenging phenomena at different investigation methods were due to intermittent protrusion into the first duodenal segment mimicking an ampulloma, but without gastric outlet syndrome or a malignant component, despite the severe anemia. Abnormal US aspect of the stomach in clinical context of anemic syndrome, requires EUS with biopsies in order to confirm underlying lesions. The particularities of this case are the: discordance between imaging aspects and the protrusion into the first duodenal segments with consecutive cholestasis mimicking an ampulloma and the lack of gastric outlet syndrome.
{"title":"Giant gastric polyp mimicking a duodenal tumor","authors":"Ioana Duca, F. Mihaileanu, A. Chira, R. Chira, Teodora Surdea Blaga, Diana Popovici, Adriana Albu, D. Dumitrascu","doi":"10.22543/2392-7674.1316","DOIUrl":"https://doi.org/10.22543/2392-7674.1316","url":null,"abstract":"Inflammatory fibroid polyps are very rare gastrointestinal tumors. We present the case of a 66-year-old woman with severe anemia and a giant gastric polyp which had intermittent duodenal intussusception. Ultrasonography showed increased gastric wall thickness and suspected an ampulloma, as revealed also by endoscopy and computed tomography. Ultrasonography reassessment showed later the intragastric mass, which was confirmed by endosonography: giant pediculated hypervascular polyp suggesting malignancy. Challenging phenomena at different investigation methods were due to intermittent protrusion into the first duodenal segment mimicking an ampulloma, but without gastric outlet syndrome or a malignant component, despite the severe anemia. Abnormal US aspect of the stomach in clinical context of anemic syndrome, requires EUS with biopsies in order to confirm underlying lesions. The particularities of this case are the: discordance between imaging aspects and the protrusion into the first duodenal segments with consecutive cholestasis mimicking an ampulloma and the lack of gastric outlet syndrome.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47861736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. A. Secara, O. Cinteză, D. Popescu, C. Popa, Camelia Andreea Hirjeu, O. Voinea, L. Serbanescu, Andreea Pauna, M. Tudosie
Vesicants are compounds that cause severe toxic effects on various tissues. Such chemical action causes tissue necrosis, with clinical expression of skin lesions with a burning character and characteristic blisters. Clinical toxic effects of cutaneous vesicles are correlated with the absorbed dose and exposure time. The goals of the study are to evaluate in vitro the skin toxicity produced by the vesicant chemical compound 2-chloroethyl-ethyl sulfide (CEES), to develop a complex antidote formula
{"title":"Innovative therapeutic approach to chemical burns produced by vesicants; an experimental study","authors":"C. A. Secara, O. Cinteză, D. Popescu, C. Popa, Camelia Andreea Hirjeu, O. Voinea, L. Serbanescu, Andreea Pauna, M. Tudosie","doi":"10.22543/2392-7674.1355","DOIUrl":"https://doi.org/10.22543/2392-7674.1355","url":null,"abstract":"Vesicants are compounds that cause severe toxic effects on various tissues. Such chemical action causes tissue necrosis, with clinical expression of skin lesions with a burning character and characteristic blisters. Clinical toxic effects of cutaneous vesicles are correlated with the absorbed dose and exposure time. The goals of the study are to evaluate in vitro the skin toxicity produced by the vesicant chemical compound 2-chloroethyl-ethyl sulfide (CEES), to develop a complex antidote formula","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43613985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mihai Faur, Dan Dumitrescu, Dan Sabau, C. Tănăsescu, Dan Cretu, D. Tănăsescu, Vlad Denis Constantin, C. Mohor
Acute pancreatitis is an acute inflammatory process of the pancreas, which can remain localized at the level of the gland or can extend to the peripancreatic and retroperitoneal tissues. The use and interpretation of paraclinical examinations at the onset can predict the form of evolution of acute pancreatitis (mild or severe). Depending on the evolution, these data are useful in determining the type of surgical intervention that might be necessary based on severity. We present a retrospective study consisting of 118 patients diagnosed and hospitalized with acute pancreatitis during 2016-2020 in the Surgery I section of the Sibiu County Emergency Clinical Hospital. Several parameters were taken into account at hospitalization such as age, sex, the environment of origin, etiology of pancreatitis, biochemical parameters with their repetition at 24, 72 hours, and at discharge, and clinical signs at hospitalization. surgeries performed depending on the severity of pancreatitis specifying their complications.
{"title":"Clinical and biological factors with prognostic value in acute pancreatitis","authors":"Mihai Faur, Dan Dumitrescu, Dan Sabau, C. Tănăsescu, Dan Cretu, D. Tănăsescu, Vlad Denis Constantin, C. Mohor","doi":"10.22543/2392-7674.1352","DOIUrl":"https://doi.org/10.22543/2392-7674.1352","url":null,"abstract":"Acute pancreatitis is an acute inflammatory process of the pancreas, which can remain localized at the level of the gland or can extend to the peripancreatic and retroperitoneal tissues. The use and interpretation of paraclinical examinations at the onset can predict the form of evolution of acute pancreatitis (mild or severe). Depending on the evolution, these data are useful in determining the type of surgical intervention that might be necessary based on severity. We present a retrospective study consisting of 118 patients diagnosed and hospitalized with acute pancreatitis during 2016-2020 in the Surgery I section of the Sibiu County Emergency Clinical Hospital. Several parameters were taken into account at hospitalization such as age, sex, the environment of origin, etiology of pancreatitis, biochemical parameters with their repetition at 24, 72 hours, and at discharge, and clinical signs at hospitalization. surgeries performed depending on the severity of pancreatitis specifying their complications.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46237593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Tănăsescu, A. Moisin, R. Fleacă, C. Popa, C. Băcilă, C. Mohor, C. Gherman, B. Gaspar, C. Tănăsescu
Diabetic foot is a severe complication of diabetes that occurs as a result of poor glycemic control, being associated with significant morbidity and mortality. Mortality associated with this disease is estimated at 5% in the first 12 months, and about 42% in the next 5 years. On average, it affects about 15% of people with diabetes during their lifetime, including as possible manifestations neuropathy, peripheral vascular disease, and subsequent ulceration which, if treated incorrectly, can lead to amputation. This paper presents a retrospective and descriptive study of patients diagnosed and treated for diabetic foot ulcers in the Proctoven Clinic. The study includes a group of 50 cases diagnosed with diabetic foot over a period of 5 years, from 01.01.2017 to 31.12.2021. In this study, the effectiveness of the modern treatment methods most frequently used in the surgical treatment of the diabetic foot is analyzed based on several parameters.
{"title":"Modern therapeutic options in diabetic foot ulcer","authors":"D. Tănăsescu, A. Moisin, R. Fleacă, C. Popa, C. Băcilă, C. Mohor, C. Gherman, B. Gaspar, C. Tănăsescu","doi":"10.22543/2392-7674.1351","DOIUrl":"https://doi.org/10.22543/2392-7674.1351","url":null,"abstract":"Diabetic foot is a severe complication of diabetes that occurs as a result of poor glycemic control, being associated with significant morbidity and mortality. Mortality associated with this disease is estimated at 5% in the first 12 months, and about 42% in the next 5 years. On average, it affects about 15% of people with diabetes during their lifetime, including as possible manifestations neuropathy, peripheral vascular disease, and subsequent ulceration which, if treated incorrectly, can lead to amputation. This paper presents a retrospective and descriptive study of patients diagnosed and treated for diabetic foot ulcers in the Proctoven Clinic. The study includes a group of 50 cases diagnosed with diabetic foot over a period of 5 years, from 01.01.2017 to 31.12.2021. In this study, the effectiveness of the modern treatment methods most frequently used in the surgical treatment of the diabetic foot is analyzed based on several parameters.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49315097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Stan, V. Botnarciuc, A. Suceveanu, A. Costea, A. Suceveanu, L. Mazilu, Ciprian Iorga, T. Hangan, C. Tudor, D. Epistatu, S. Chirila, Viorel Gherghina, F. Voinea
Objectives . The objective of this study was to evaluate the potential use of Prostate Imaging – Reporting and Data System version 2 (PI-RADS) in combination with Glutathione S-transferase P1 (GST-P1) expression for an improved diagnosis of prostate cancer, in patients with inconclusive values of prostate-specific antigen (PSA). Materials and Methods . The study was conducted on 80 patients for whom PSA values were evaluated and were found to be inconclusive (4-10 ng/ml). These patients underwent imagistic evaluation (PI-RADS), followed by transurethral prostate biopsy, with the evaluation of GST-P1 expression and histopathological examination (for diagnosis confirmation). Results . By combining the results of PI-RADS and GST-P1 the capacity of the tests to correctly identify healthy subjects, with an area under curve of 0,832 (95% CI 0.732–0.907), with a sensitivity of 73,25% and a specificity of 77,78%. Conclusions . PI-RADS lesions and GST-P1 methylation testing when PSA levels are in a “grey zone”, provide a better specificity and sensitivity by comparison through single testing. Testing patients with inconclusive PSA levels allows for a more accurate diagnosis and less over-diagnosis by non-invasive procedures, such as repeated biopsies.
目标。本研究的目的是评估前列腺成像报告和数据系统版本2 (PI-RADS)与谷胱甘肽s -转移酶P1 (GST-P1)表达结合在前列腺特异性抗原(PSA)值不确定的患者中改善前列腺癌诊断的潜在用途。材料与方法。该研究对80名患者进行了PSA值评估，发现不确定(4-10 ng/ml)。这些患者接受影像学评估(PI-RADS)，然后经尿道前列腺活检，评估GST-P1表达和组织病理学检查(用于诊断确认)。结果。通过结合PI-RADS和GST-P1的结果，测试正确识别健康受试者的能力，曲线下面积为0,832 (95% CI 0.732-0.907)，灵敏度为73.25%，特异性为77.78%。结论。当PSA水平处于“灰色地带”时，PI-RADS病变和GST-P1甲基化检测通过单次检测比较具有更好的特异性和敏感性。检测不确定PSA水平的患者可以通过非侵入性程序(如重复活检)进行更准确的诊断和更少的过度诊断。
{"title":"Prostate Imaging Reporting and Data System score (PI-RADS) and Glutathione S-transferase P1 methylation status (GST-P1) in the diagnosis of prostate cancer patients with borderline PSA values","authors":"M. Stan, V. Botnarciuc, A. Suceveanu, A. Costea, A. Suceveanu, L. Mazilu, Ciprian Iorga, T. Hangan, C. Tudor, D. Epistatu, S. Chirila, Viorel Gherghina, F. Voinea","doi":"10.22543/2392-7674.1354","DOIUrl":"https://doi.org/10.22543/2392-7674.1354","url":null,"abstract":"Objectives . The objective of this study was to evaluate the potential use of Prostate Imaging – Reporting and Data System version 2 (PI-RADS) in combination with Glutathione S-transferase P1 (GST-P1) expression for an improved diagnosis of prostate cancer, in patients with inconclusive values of prostate-specific antigen (PSA). Materials and Methods . The study was conducted on 80 patients for whom PSA values were evaluated and were found to be inconclusive (4-10 ng/ml). These patients underwent imagistic evaluation (PI-RADS), followed by transurethral prostate biopsy, with the evaluation of GST-P1 expression and histopathological examination (for diagnosis confirmation). Results . By combining the results of PI-RADS and GST-P1 the capacity of the tests to correctly identify healthy subjects, with an area under curve of 0,832 (95% CI 0.732–0.907), with a sensitivity of 73,25% and a specificity of 77,78%. Conclusions . PI-RADS lesions and GST-P1 methylation testing when PSA levels are in a “grey zone”, provide a better specificity and sensitivity by comparison through single testing. Testing patients with inconclusive PSA levels allows for a more accurate diagnosis and less over-diagnosis by non-invasive procedures, such as repeated biopsies.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47321135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniela-Mădălina Ciucă Anghel, Elena-Elisabeta Anghel, M. Stan, Gheorghe Tudor, A. Dumitriu, S. Păunică, D. Baconi
Aim . We aimed to assess the differences among various groups of drugs users, especially in the psychiatric and psychological domains. Materials and Methods . A retrospective study was carried out in collaboration with C.E.T
{"title":"Psychological and psychiatric characterization of various groups of drugs users","authors":"Daniela-Mădălina Ciucă Anghel, Elena-Elisabeta Anghel, M. Stan, Gheorghe Tudor, A. Dumitriu, S. Păunică, D. Baconi","doi":"10.22543/2392-7674.1356","DOIUrl":"https://doi.org/10.22543/2392-7674.1356","url":null,"abstract":"Aim . We aimed to assess the differences among various groups of drugs users, especially in the psychiatric and psychological domains. Materials and Methods . A retrospective study was carried out in collaboration with C.E.T","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47381587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We propose a computer modeling approach for SARS-CoV-2 transmission that can be preferable to a purely mathematical framework. It is illustrated its functionality in a specific case of indoor transmission. Based on literature, we assume that infection is due to aerosols with viral particles that persist and accumulate for hours in the air even after the persons who produced them left the space. We incorporate also restricted opening hours as a mitigation measure and one possible behavioral change in response to this measure. It is shown via several examples how this algorithmic modeling approach can be used to run various scenarios in order to predict the efficacy of the intervention.
{"title":"An algorithm for indoor SARS-CoV-2 transmission","authors":"D. Maxin, S. Gannon","doi":"10.22543/2392-7674.1313","DOIUrl":"https://doi.org/10.22543/2392-7674.1313","url":null,"abstract":"We propose a computer modeling approach for SARS-CoV-2 transmission that can be preferable to a purely mathematical framework. It is illustrated its functionality in a specific case of indoor transmission. Based on literature, we assume that infection is due to aerosols with viral particles that persist and accumulate for hours in the air even after the persons who produced them left the space. We incorporate also restricted opening hours as a mitigation measure and one possible behavioral change in response to this measure. It is shown via several examples how this algorithmic modeling approach can be used to run various scenarios in order to predict the efficacy of the intervention.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49384556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Silaghi, B. Gaspar, D. Epistatu, D. Balan, I. Păunică, A. Dumitriu, S. Păunică, B. Socea, V. Constantin
SARS-COV 2 recently caused a global pandemic, with the first case being reported in Romania in February 2020. Important restrictive measures were imposed, so that the addressability of patients to medical services decreased. Upper gastrointestinal bleeding had more severe forms of evolution at the time of presentation, which required additional methods of diagnosis and treatment. This is a retrospective study performed on 268 patients, which aims to evaluate the type and effectiveness of different treatment methods for upper gastrointestinal bleeding during the COVID 19 pandemic. Severity assessment was performed by measuring the Rockall score and additional methods of diagnosis. The association of COVID-19 with upper gastrointestinal bleeding can lead to much more severe outcomes for the patient, so treatment must be sustained and fast established. If the initial therapeutic methods fail, the other available therapeutic measures should be introduced progressively and without delay to achieve the best possible outcomes.
{"title":"Upper gastrointestinal bleeding during the COVID-19 pandemic; particularities of diagnosis and therapy","authors":"A. Silaghi, B. Gaspar, D. Epistatu, D. Balan, I. Păunică, A. Dumitriu, S. Păunică, B. Socea, V. Constantin","doi":"10.22543/2392-7674.1363","DOIUrl":"https://doi.org/10.22543/2392-7674.1363","url":null,"abstract":"SARS-COV 2 recently caused a global pandemic, with the first case being reported in Romania in February 2020. Important restrictive measures were imposed, so that the addressability of patients to medical services decreased. Upper gastrointestinal bleeding had more severe forms of evolution at the time of presentation, which required additional methods of diagnosis and treatment. This is a retrospective study performed on 268 patients, which aims to evaluate the type and effectiveness of different treatment methods for upper gastrointestinal bleeding during the COVID 19 pandemic. Severity assessment was performed by measuring the Rockall score and additional methods of diagnosis. The association of COVID-19 with upper gastrointestinal bleeding can lead to much more severe outcomes for the patient, so treatment must be sustained and fast established. If the initial therapeutic methods fail, the other available therapeutic measures should be introduced progressively and without delay to achieve the best possible outcomes.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45992729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Holeva, V. Nikopoulou, E. Parlapani, Konstantinos Karkaletsis, Styliani Kokkoni, D. Nouvakis, P. Theocharis, I. Diakogiannis
Older age renders individuals vulnerable during public emergency crises. Considering that older adults are a highly heterogeneous and continuously growing demographic subgroup, this study aimed to assess the mental health impact of COVID-19 on two groups of older patients: a group of chronic physical disease and a group of chronic mental disease. A total of 102 patients completed the Fear of COVID-19 Scale, the Generalized Anxiety Disorder scale, the Brief Patient Health Questionnaire (PHQ-9) and several questions regarding demographic characteristics. Suicidality was assessed by the 9th item of the PHQ-9. According to the results, older chronic disease patients showed higher levels of fear, whereas anxiety and depressive symptoms were present mainly in the group of older psychiatric patients. Suicidality was reported from a subtotal of 25.4% that was composed of 7.8% chronic disease patients and 17.6% psychiatric patients. Chronic physical disease and higher anxiety predicted more severe COVID-19-related fear.
{"title":"Fear of COVID-19, anxiety, depression and suicide among elderly patients with chronic physical or mental diseases","authors":"V. Holeva, V. Nikopoulou, E. Parlapani, Konstantinos Karkaletsis, Styliani Kokkoni, D. Nouvakis, P. Theocharis, I. Diakogiannis","doi":"10.22543/2392-7674.1318","DOIUrl":"https://doi.org/10.22543/2392-7674.1318","url":null,"abstract":"Older age renders individuals vulnerable during public emergency crises. Considering that older adults are a highly heterogeneous and continuously growing demographic subgroup, this study aimed to assess the mental health impact of COVID-19 on two groups of older patients: a group of chronic physical disease and a group of chronic mental disease. A total of 102 patients completed the Fear of COVID-19 Scale, the Generalized Anxiety Disorder scale, the Brief Patient Health Questionnaire (PHQ-9) and several questions regarding demographic characteristics. Suicidality was assessed by the 9th item of the PHQ-9. According to the results, older chronic disease patients showed higher levels of fear, whereas anxiety and depressive symptoms were present mainly in the group of older psychiatric patients. Suicidality was reported from a subtotal of 25.4% that was composed of 7.8% chronic disease patients and 17.6% psychiatric patients. Chronic physical disease and higher anxiety predicted more severe COVID-19-related fear.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41915042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ruxandra Oana Alius, V. Zainea, Cătălina Voiosu, I. Ioniță, A. Rusescu, O. Bălălău, Cătălin Aliuș, Raluca Oana Pulpa, R. Hainăroșie
The endemic spread of obesity and unhealthy behaviors of modern society led to revisiting the real prevalence related to obstructive sleep apnea. Recent data support a paradigm shift towards individually tailored treatments which include functional surgery of the upper airways. This paper presents the results of a randomized interventional, prospective study on 68 patients referred by the general practitioner for obstructive sleep apnea. The eligible cohort consisted of 28 patients who were offered functional surgery for definitive relief of obstructive symptoms. After topographic diagnosis of the obstruction site and grading of the severity of the obstructive sleep apnea, the eligible lot was randomized for either nasal surgery or pharyngeal surgery. Subjective and objective measurements were carried out at presentation and three months after surgery. Results showed a significant reduction in AHI (more than 50%) after functional surgery, with marginal benefit for those treated with nasal surgery. Functional improvement is unequivocal for both surgical methods, but the superior results reported in the nasal surgery group could be related to the relatively small size of the study group. The involvement of a larger cohort in subsequent studies with a similar design could confirm these results.
{"title":"Nasal surgery versus pharyngeal surgery in the treatment of obstructive sleep apnea","authors":"Ruxandra Oana Alius, V. Zainea, Cătălina Voiosu, I. Ioniță, A. Rusescu, O. Bălălău, Cătălin Aliuș, Raluca Oana Pulpa, R. Hainăroșie","doi":"10.22543/2392-7674.1347","DOIUrl":"https://doi.org/10.22543/2392-7674.1347","url":null,"abstract":"The endemic spread of obesity and unhealthy behaviors of modern society led to revisiting the real prevalence related to obstructive sleep apnea. Recent data support a paradigm shift towards individually tailored treatments which include functional surgery of the upper airways. This paper presents the results of a randomized interventional, prospective study on 68 patients referred by the general practitioner for obstructive sleep apnea. The eligible cohort consisted of 28 patients who were offered functional surgery for definitive relief of obstructive symptoms. After topographic diagnosis of the obstruction site and grading of the severity of the obstructive sleep apnea, the eligible lot was randomized for either nasal surgery or pharyngeal surgery. Subjective and objective measurements were carried out at presentation and three months after surgery. Results showed a significant reduction in AHI (more than 50%) after functional surgery, with marginal benefit for those treated with nasal surgery. Functional improvement is unequivocal for both surgical methods, but the superior results reported in the nasal surgery group could be related to the relatively small size of the study group. The involvement of a larger cohort in subsequent studies with a similar design could confirm these results.","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41972915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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