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Perceived Stress and Religious Coping among Pakistani-Origin Emerging Muslim Adults Living in Pakistan and the United States: A Cross-Cultural View 生活在巴基斯坦和美国的巴基斯坦裔新兴穆斯林成年人的感知压力和宗教应对:一个跨文化的观点
Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-10-31 DOI: 10.22543/2392-7674.1431
Amna Khan, Kiran Bashir Ahmed
This study explored the relationship between Perceived Stress and Religious Coping levels among Muslim emerging adults of Pakistani origin living in Pakistan and Muslim emerging adults of Pakistani origin living in the United States (US). Participants (Pakistani Origin Muslims Living in Pakistan, n= 103; and Pakistani Origin Muslims Living in the US, n=50) were between 18-25 years old. The Perceived Stress Scale (PSS-10) and Brief R-Cope scale were administered using an online format. Results indicated that negative religious coping strategies were associated with higher perceived stress in both groups while positive religious coping strategies showed a weaker association with lower perceived stress levels, and this finding appeared only in the US sample. Marital status was also an important predictor of perceived stress. These findings demonstrate that Muslim emerging adults, irrespective of culture, show moderately similar patterns in their perception of stress and their utilization of religious coping strategies.
本研究探讨了生活在巴基斯坦的巴基斯坦裔穆斯林新生成人和生活在美国的巴基斯坦裔穆斯林新生成人感知压力与宗教应对水平之间的关系。参与者(居住在巴基斯坦的巴基斯坦裔穆斯林,n= 103;和居住在美国的巴基斯坦裔穆斯林(n=50)年龄在18-25岁之间。感知压力量表(PSS-10)和简要R-Cope量表采用在线格式进行管理。结果表明,在两组中,消极的宗教应对策略与较高的感知压力相关,而积极的宗教应对策略与较低的感知压力水平的关联较弱,这一发现仅出现在美国样本中。婚姻状况也是感知压力的重要预测指标。这些发现表明,无论文化背景如何,穆斯林新生成人在对压力的感知和对宗教应对策略的使用上都表现出适度相似的模式。
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引用次数: 0
Coxarthrosis etiology influences the patients’ quality of life in the preoperative and postoperative phase of total hip arthroplasty 关节病病因影响全髋关节置换术术前和术后患者的生活质量
Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-10-31 DOI: 10.22543/2392-7674.1412
Madalin Bulzan, Simona Cavalu, Amir Mohamed Abdelhamid, Calin Tudor Hozan, Florica Voiţă-Mekeres
Background. In orthopedics, the patients’ quality of life relative to the preoperative and postoperative phase is referred with a low impact compared to other branches of medicine. In this context, our interest focused on assessing the quality of life in patients with traumatic and non-traumatic coxarthrosis by longitudinally following the evolution of the patients. Materials and Methods. The well-established instrument Short Form Survey SF-36 was applied in a retrospective study, conducted on a cohort of 203 participants who underwent THA (Total Hip Arthroplasty). Statistical analysis was generated using GraphPad Prism (version 9.5.1). Results. In the pre-operative phase, physical functioning was more affected in participants with traumatic coxarthrosis, while fatigue was specific to nontraumatic coxarthrosis. Emotional well-being and social functioning were high in patients with traumatic coxarthrosis. One month after surgery, we recorded an increased physical functioning and improvement in the perception of the ability to exercise roles in non-traumatic group. Energy/vitality and general health and well-being were at high level in traumatic group, 1st month post-surgery, although pain was still frequent. Age was the sole strong independent predictor of postoperative physical functioning in the traumatic group, while in the non-traumatic group, we identified gender, age, symptoms and type of prosthesis as strong predictors of postoperative physical functioning. The overall results related to daily living activities indicated that the traumatic group displayed more favorable post-surgery evolution and higher autonomy compared to the non-traumatic one. Conclusions. We conclude that SF-36 questionnaire is a specific, useful and inexpensive tool for evaluating the outcomes of orthopedic treatment and patients’ evolution after arthroplasty, especially in terms of functional outcome scores relative to coxarthrosis etiology.
背景。在骨科中,患者的生活质量相对于术前和术后阶段,与其他医学分支相比影响较小。在这种情况下,我们的兴趣集中在通过纵向跟踪患者的演变来评估创伤性和非创伤性关节关节病患者的生活质量。材料与方法。在一项回顾性研究中,采用了完善的Short Form Survey SF-36工具,对203名接受全髋关节置换术的参与者进行了队列研究。使用GraphPad Prism(9.5.1版本)进行统计分析。结果。在术前阶段,外伤性肩关节病患者的身体功能受到的影响更大,而疲劳是非外伤性肩关节病患者特有的。外伤性关节关节病患者的情绪幸福感和社会功能较高。手术后一个月,我们记录了非创伤组患者身体功能的增强和对运动角色的感知能力的改善。术后1个月,创伤组的能量/活力和总体健康和幸福感处于较高水平,尽管疼痛仍然频繁。在创伤组中,年龄是术后肢体功能的唯一独立预测因素,而在非创伤组中,我们发现性别、年龄、症状和假体类型是术后肢体功能的重要预测因素。日常生活活动的总体结果表明,创伤组比非创伤组表现出更有利的术后进化和更高的自主性。结论。我们得出结论,SF-36问卷是评估骨科治疗结果和关节置换术后患者发展的一个特定的、有用的和廉价的工具,特别是在关节关节病病因的功能结局评分方面。
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引用次数: 0
Evaluating the effectiveness of chess as a therapeutic tool in the comprehensive management of ADHD 评估象棋作为ADHD综合治疗工具的有效性
Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-10-31 DOI: 10.22543/2392-7674.1405
Neilay Krishna Agarwal
Using databases such as PubMed and Google Scholar with the keywords "Chess" and "ADHD", this study was conducted to review the literature on the usefulness of chess in patients with ADHD. The most relevant articles were searched using the following criteria: English language, and all types of studies published in a medical journal. A total 12 articles were identified. Of a total of 12 articles, 4 met the inclusion criteria and were subsequently reviewed. The results of the review showed that chess therapy/training is effective in the management of ADHD patients in terms of reducing symptoms and severity. Due to its effectiveness, playful nature, high adherence and low cost, it can be used as a therapeutic tool in multimodal management to improve ADHD symptoms. Considering the limited number of published studies in this field, our findings need to be confirmed by further controlled, randomized and extended studies. In our investigation, we found no study evaluating the effectiveness of chess in the adult subgroup of the ADHD population.
本研究使用PubMed和Google Scholar等数据库,以“Chess”和“ADHD”为关键词,对国际象棋对ADHD患者有用性的文献进行综述。使用以下标准搜索最相关的文章:英语,以及在医学杂志上发表的所有类型的研究。共鉴定出12件物品。在总共12篇文章中,有4篇符合纳入标准,随后进行了审查。回顾的结果表明,象棋治疗/训练在减轻症状和严重程度方面对ADHD患者的管理是有效的。由于它的有效性、游戏性、高依从性和低成本,它可以作为多模式管理的治疗工具来改善ADHD症状。考虑到该领域发表的研究数量有限,我们的发现需要进一步的对照、随机和扩展研究来证实。在我们的调查中,我们发现没有研究评估国际象棋在ADHD人群的成人亚组中的有效性。
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引用次数: 0
Endoscopic approach to recurrent inguinal hernia after previous open surgery 内镜入路治疗既往开放手术后复发性腹股沟疝
Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-10-31 DOI: 10.22543/2392-7674.1402
Doru Moga, Dragos Serban, Bogdan Geavlete, Crenguta Serboiu, Bogdan Serban, Ana Maria Dascalu, Valentin Oprea
Background. The management of a recurrent inguinal hernia varies depending on multiple factors. In the case of recurrent inguinal hernias after open anterior repair, the laparoscopic approach is recommended. TEP and TAPP procedures are considered to have similar results. The purpose of the study is to evaluate on our sample if there are differences between primary inguinal hernia cases and recurrent hernia after laparoscopic TAPP and TEP procedures. Materials and Methods. We retrospectively reviewed the medical records of 300 patients who underwent laparoscopic inguinal hernia repairs at our hospital from March 2013 to March 2023. Results. Of the 300 patients, 39 of them (13%) had recurrent hernias after open anterior procedures. The mean age of patients with recurrent hernias was 56.82 years, compared to 50.47 years in those with primary hernias. In 27 cases we used the TAPP approach (69%), while in the remaining 12 cases the TEP approach (31%). Operative time for recurrent hernias was 72.69 minutes as opposed to 58.49 minutes for primary hernias. The percentage of peritoneal tears was higher for recurrent hernias (38%) than for primary hernias (18%). Conclusions. Surgery for inguinal hernia recurrence, is often more complex and time-consuming than for a primary hernia. However, postoperative results are favorable, with a low complication rate. Out of the two minimally invasive approach options, TAPP is our choice, especially due to the increased incidence of peritoneal tears.
背景。复发性腹股沟疝的处理取决于多种因素。如果腹股沟疝复发后开放前修补,腹腔镜方法是推荐的。TEP和TAPP程序被认为具有相似的结果。本研究的目的是评估我们的样本在腹腔镜TAPP和TEP手术后原发性腹股沟疝和复发性腹股沟疝之间是否存在差异。材料与方法。我们回顾性分析了2013年3月至2023年3月在我院行腹腔镜腹股沟疝修补术的300例患者的医疗记录。结果。在300例患者中,39例(13%)在开放性前路手术后复发疝。复发性疝患者的平均年龄为56.82岁,而原发性疝患者的平均年龄为50.47岁。27例采用TAPP入路(69%),其余12例采用TEP入路(31%)。复发疝的手术时间为72.69分钟,而原发性疝的手术时间为58.49分钟。腹膜撕裂在复发性疝中的比例(38%)高于原发性疝(18%)。结论。腹股沟疝复发的手术通常比原发性疝更复杂和耗时。然而,术后结果良好,并发症发生率低。在两种微创入路选择中,TAPP是我们的选择,特别是由于腹膜撕裂的发生率增加。
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引用次数: 0
Diabetes mellitus: interdisciplinary medical, surgical and psychological therapeutic approach 糖尿病:跨学科的医学、外科和心理治疗方法
Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-10-31 DOI: 10.22543/2392-7674.1445
Bogdan Socea, Adrian Silaghi, Laura Florentina Rebegea, Daniela Gabriela Balan, Cristian Balalau, Tiberiu Ștefăniță Tenea-Cojan, Doina Andrada Mihai, Ioana Paunica
Diabetes mellitus is a complex and widespread metabolic disease, having extremely complex implications (biological, psychological, social) for patients. Understanding the pathophysiology of diabetes (majorly influenced by various factors such as genetic predisposition, age, lifestyle choices, etc.) is essential for the prevention of this condition and the establishment of effective treatment strategies. The latest and relevant literature data related to the epidemiology, pathophysiology, and treatment of diabetes are presented, after an exhaustive review of the articles published on this topic and indexed in the WOS, PubMed, Scopus and Google Scholar databases. Preventing or delaying the onset of diabetes can be achieved in some patients with type 2 diabetes. After onset, treatment of diabetes is complex, involving a comprehensive approach (pharmacological interventions, lifestyle changes, surgical interventions in selected cases, as well as psychological support), depending on the stage of the disease and possible associated complications. Finally, diabetes is often asymptomatic in the initial stages, so an early diagnosis remains the essential element for the best subsequent therapeutic control.
糖尿病是一种复杂而广泛的代谢性疾病,对患者具有极其复杂的生理、心理和社会影响。了解糖尿病的病理生理(主要受遗传易感性、年龄、生活方式选择等多种因素的影响)对于预防糖尿病和制定有效的治疗策略至关重要。在对WOS、PubMed、Scopus和谷歌Scholar数据库中已发表的有关该主题的文章进行了详尽的综述后,介绍了与糖尿病流行病学、病理生理学和治疗相关的最新相关文献数据。在一些2型糖尿病患者中,预防或延缓糖尿病的发生是可以实现的。发病后,糖尿病的治疗是复杂的,涉及综合方法(药物干预、改变生活方式、选定病例的手术干预以及心理支持),这取决于疾病的阶段和可能的相关并发症。最后,糖尿病在初始阶段通常是无症状的,因此早期诊断仍然是最佳后续治疗控制的基本要素。
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引用次数: 0
From COVID-19 to long COVID; the forms of the neurological manifestations 从COVID-19到长COVID;神经系统表现的形式
Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-10-31 DOI: 10.22543/2392-7674.1403
Sana Ahuja, Sufian Zaheer
Ever since the SARS-CoV-2 infection was declared a global pandemic in 2020, numerous multisystemic manifestations have been discovered. The COVID-19 is known to cause a wide spectrum of neurological symptoms like fatigue, headache, brain fog, stroke, smell and taste disorders, encephalopathy and neurodegenerative disorders. The neurological manifestations are more prevalent in the post-COVID syndrome or long COVID. The National Institute for Health and Care Excellence and WHO defined Ongoing Symptomatic COVID as 4-12 weeks post infection and post COVID-19 syndrome as persistence of symptoms beyond 12 weeks. So far there are limited data available regarding the pathophysiology of neurological symptoms of prolonged COVID, although neuroinflammation and oxidative damage have been implicated. In this review article, we have highlighted the transition from COVID to long-term COVID, focusing the discussion particularly on neurological complications.
自2020年宣布SARS-CoV-2感染成为全球大流行以来,已经发现了许多多系统表现。已知COVID-19会引起广泛的神经系统症状,如疲劳、头痛、脑雾、中风、嗅觉和味觉障碍、脑病和神经退行性疾病。神经系统表现在COVID后综合征或长COVID中更为普遍。美国国家卫生与保健卓越研究所和世卫组织将持续症状性COVID定义为感染后4-12周,将COVID-19后综合征定义为症状持续12周以上。到目前为止,关于长期COVID的神经系统症状的病理生理学数据有限,尽管已经涉及神经炎症和氧化损伤。在这篇综述文章中,我们强调了从COVID到长期COVID的过渡,特别关注神经系统并发症的讨论。
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引用次数: 0
Revascularization impact: quality of life enhancement in chronic limb-threatening ischemia 血运重建的影响:慢性肢体缺血患者生活质量的提高
Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-10-31 DOI: 10.22543/2392-7674.1441
Cristian Traian Paius, Vlad Denis Constantin, Alexandru Carap, Andrei Tarus, Grigore Tinica
Introduction. Globally, over 230 million people have peripheral artery disease, often undiagnosed, leading to chronic limb-threatening ischemia. Revascularization is vital for preventing amputation and improving quality of life. While specific questionnaires for severe ischemia are lacking, the SF-36 questionnaire is widely used to assess quality of life, with variations like SF-12 and SF-8 for larger cohorts. Objectives. Our aim was to assess how different lower limb revascularization methods affect the postoperative quality of life in patients with chronic limb-threatening ischemia. Methods. This study was conducted at the St. Pantelimon Emergency Hospital of Bucharest, Romania. It included 166 adult patients with chronic limb-threatening ischemia who were monitored for 12 months. Quality of life was assessed using the SF-36 questionnaire. The patients were categorized into two groups: 112 underwent conventional surgery, and 54 had hybrid procedures. Data analysis involved t-tests, Mann-Whitney U tests and assessment of data reliability. Results. In the Conventional Surgery group, the average age was 70.5 years, predominantly male, with similar risk factors as the second group. The Hybrid Surgery group had an average age of 73 and exhibited more extensive distal arterial lesions, higher rates of ulcer/gangrene, and a higher occurrence of postoperative minor amputations. The SF-36 questionnaire showed low data reliability for the General Health and Social Functioning domains. Additionally, the Hybrid Surgery group had poorer preoperative perception in the Body Pain category. However, significant postoperative improvements in quality of life were observed in all domains for both groups with similar results. Conclusions. Revascularization improves the quality of life for patients with chronic limb-threatening ischemia, including those that also require minor amputations. SF-36 has good assessment for most QoL aspects, but reliability declines in severe ischemia.
介绍。在全球范围内,超过2.3亿人患有外周动脉疾病,往往未得到诊断,导致慢性肢体缺血。血运重建对于预防截肢和提高生活质量至关重要。虽然缺乏针对严重缺血的具体问卷,但SF-36问卷被广泛用于评估生活质量,在更大的队列中使用SF-12和SF-8等变量。目标。我们的目的是评估不同的下肢血运重建方法对慢性肢体缺血患者术后生活质量的影响。方法。这项研究是在罗马尼亚布加勒斯特的圣潘蒂蒙急救医院进行的。该研究包括166名患有慢性肢体威胁缺血的成年患者,他们被监测了12个月。使用SF-36问卷评估生活质量。患者被分为两组:112人接受常规手术,54人接受混合手术。数据分析包括t检验、Mann-Whitney U检验和数据可靠性评估。结果。在常规手术组中,平均年龄为70.5岁,以男性为主,危险因素与第二组相似。混合手术组平均年龄为73岁,远端动脉病变范围更广,溃疡/坏疽发生率更高,术后小截肢发生率更高。SF-36问卷显示一般健康和社会功能领域的数据可靠性较低。此外,混合手术组在身体疼痛类别中术前感知较差。然而,两组在所有领域的术后生活质量均有显著改善,结果相似。结论。血运重建术改善了慢性肢体缺血患者的生活质量,包括那些需要轻微截肢的患者。SF-36在大多数生活质量方面具有良好的评价,但在严重缺血时可靠性下降。
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引用次数: 0
Barrett's esophagus as a premalignant condition; medical and surgical therapeutic management 巴雷特食管是一种癌前病变;内科和外科治疗管理
Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-10-31 DOI: 10.22543/2392-7674.1443
Vlad Denis Constantin, Adrian Silaghi, Laura Florentina Rebegea, Stana Paunica, Anca Silvia Dumitriu, Doina Andrada Mihai, Ioana Paunica, Dragos Epistatu
Barrett's esophagus (BE) represents a special clinical entity, which may have reduced symptoms, but an increased potential for malignant degeneration. The factors that lead to the appearance of Barrett's esophagus are multiple, the most important being gastro-esophageal reflux, as well as smoking and obesity. BE occurs as a result of damage of the esophageal mucosa, caused by acid/basic gastroesophageal reflux and resulting in the transformation of the epithelium from squamous to intestinal type. The diagnosis of BE is primarily based on endoscopic examination. This method has not only a diagnostic role, but also a therapeutic one through the minimally invasive resection of the mucosa with suspicious dysplastic lesions, thus reducing the risk of esophageal adenocarcinoma. Conservative therapeutic methods by administering chemoprotective agents (proton pump inhibitors, statins, etc.) are also useful. Surgical treatment of Barrett's esophagus aims to both resect areas of high-grade esophageal dysplasia/adenocarcinoma and reduce the degree of gastroesophageal reflux through various surgical procedures. As a conclusion, the potential for malignant degeneration of BE should not be neglected, the form of treatment largely depending on the patient's age and comorbidities.
巴雷特食管(BE)是一种特殊的临床疾病,其症状可能减轻,但恶性变性的可能性增加。导致巴雷特食管出现的因素是多方面的,最重要的是胃食管反流,以及吸烟和肥胖。BE的发生是由于胃酸/碱性胃食管反流引起的食管黏膜损伤,导致上皮从鳞状上皮转变为肠型。BE的诊断主要基于内窥镜检查。该方法不仅具有诊断作用,而且具有治疗作用,通过微创切除可疑发育不良病变的粘膜,从而降低发生食管腺癌的风险。使用化学保护剂(质子泵抑制剂,他汀类药物等)的保守治疗方法也是有用的。Barrett食管的手术治疗旨在切除高级别食管发育不良/腺癌区域,并通过各种手术方式降低胃食管反流程度。综上所述,BE恶性变性的可能性不容忽视,治疗的形式很大程度上取决于患者的年龄和合并症。
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引用次数: 0
Is open surgery still part of the current treatment of inguinal hernias? 开放手术仍然是目前腹股沟疝治疗的一部分吗?
Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-10-31 DOI: 10.22543/2392-7674.1413
Dan Bratu, Alin Mihetiu, Alexandra Sandu, Crenguta Serboiu, Corneliu Tudor, Laurentiu Simion, Dragos Cretoiu, Florin Bobirca, Dragos Davitoiu, Bogdan Serban, Claudiu Eduard Nistor
Inguinal hernia repair represents one of the most frequent pathologies with surgical addressability. From the multitude of surgical procedures, a limited number still keep their indication in the current treatment of hernias. Open surgery, the exclusive repair method until recently, is associated with laparoscopic techniques with benefits that are at least superposable on those in open repair. We conducted a study, analyzing several types of procedures in open surgery and comparing them to each other, but also with the TAPP approach, which is still at the beginning in our service. The non-mesh procedures scored poorly in terms of recurrence, the duration of the surgical intervention, and complications of the pain type, the Lichtenstein procedure was frequently associated with non-infectious inflammatory complications, and the TAPP, which is still in the learning curve, presented a prolonged duration of the surgical intervention. The Lichtenstein procedure maintains its usefulness and represents the most frequent technique for sanctioning inguinal hernia, the non-mesh processes, less used lately, are more frequently preferred in situations where hernia strangulation is associated with a septic complication. Open surgery hernia repair remains a feasible option in the era of minimal invasiveness, especially under the conditions of performing a tension-free technique, for specific categories of patients or surgical services remaining the first intention solution.
腹股沟疝修补是外科治疗中最常见的病理之一。从众多的外科手术中,在目前的疝气治疗中,有限的一些手术仍然保持着它们的指征。开放手术,唯一的修复方法,直到最近,是与腹腔镜技术的好处,至少重叠在那些开放修复。我们进行了一项研究,分析了几种开放手术的程序,并将它们相互比较,同时也与TAPP方法进行了比较,TAPP方法在我们的服务中仍处于起步阶段。非补片手术在复发、手术干预持续时间和疼痛类型并发症方面得分较低,利希滕斯坦手术经常伴有非感染性炎症并发症,TAPP仍处于学习阶段,手术干预持续时间较长。Lichtenstein手术保持了它的有效性,代表了腹股沟疝的最常用技术,非补片手术,最近较少使用,在疝绞窄与脓毒性并发症相关的情况下更常用。在微创时代,开放手术疝修补仍然是一种可行的选择,特别是在执行无张力技术的条件下,对于特定类别的患者或手术服务仍然是首选解决方案。
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引用次数: 0
Prevalence of comorbidities and survival analysis of COVID-19 patients – an observational study from a tertiary healthcare center in North West Romania COVID-19患者合并症患病率和生存分析——来自罗马尼亚西北部三级卫生保健中心的观察性研究
Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-10-31 DOI: 10.22543/2392-7674.1401
Mihaela Simona Popoviciu, Lorena Paduraru, Roxana Adriana Stoica, Anca Pantea Stoian, Claudiu Teodorescu, Simona Cavalu
Objectives. The experience accumulated in the last two years shows that the prevention of COVID-19 in people with comorbidities (protective measures, vaccination, etc.) still remains a public health priority. In this context, the aim of our study was to perform a retrospective, observational study in order to assess the time-to-death and risk factors of mortality among COVID-19 patients. Materials and Methods. The study was conducted on 177 patients admitted to Oradea Emergency County Hospital, Bihor, Romania, between October and December 2021. Inclusion criteria were patients over 18 years positive for COVID-19 in upper respiratory tract samples using real-time PCR test. Exclusion criteria were pregnant women, ageyears, and patients with incomplete records at admission. Results. The mortality rate was assessed in correlation with the most prevalent comorbidities such as diabetes, cardiovascular diseases, hypertension, chronic kidney disease, and chronic pulmonary diseases, either alone or associated. During hospitalization, an aggravated health condition was noticed for 71 patients (40.11%). Among them, 47 patients were transferred to the intensive care unit (66.20%) due to severe respiratory failure, aggravation of associated diabetes and/or other associated comorbidities. Ventilation support was necessary in 122 cases (68.63%). The average survival time was 8.66 days. In conclusion, we found that the most prevalent comorbidities were cardiovascular diseases, being the major risk factor for mortality or aggravation after hospitalization. Its association with diabetes caused a risk of death 2.1 times higher than in patients without comorbidities. Based on Kaplan–Meier survival analysis, we found that the in-hospital survival rate was significantly higher in females compared to males (50.52% vs 33.75%).
目标。过去两年积累的经验表明,在有合并症的人群中预防COVID-19(保护措施、疫苗接种等)仍然是公共卫生重点。在此背景下,本研究的目的是进行一项回顾性观察性研究,以评估COVID-19患者的死亡时间和死亡危险因素。材料与方法。该研究是在2021年10月至12月期间对罗马尼亚比霍尔奥拉迪亚急诊县医院收治的177名患者进行的。入选标准为18岁以上上呼吸道标本COVID-19阳性患者,采用实时荧光定量PCR检测。排除标准为孕妇、年龄和入院时记录不完整的患者。结果。死亡率与最普遍的合并症(如糖尿病、心血管疾病、高血压、慢性肾脏疾病和慢性肺部疾病)的相关性进行了评估,无论是单独的还是相关的。住院期间,71例(40.11%)患者出现健康状况恶化。其中47例(66.20%)因严重呼吸衰竭、合并糖尿病加重和/或其他相关合并症转入重症监护病房。122例(68.63%)需要通气支持。平均生存时间为8.66 d。总之,我们发现最常见的合并症是心血管疾病,是住院后死亡或病情加重的主要危险因素。其与糖尿病的相关性导致死亡风险比无合并症患者高2.1倍。基于Kaplan-Meier生存分析,我们发现女性的住院生存率明显高于男性(50.52% vs 33.75%)。
{"title":"Prevalence of comorbidities and survival analysis of COVID-19 patients – an observational study from a tertiary healthcare center in North West Romania","authors":"Mihaela Simona Popoviciu, Lorena Paduraru, Roxana Adriana Stoica, Anca Pantea Stoian, Claudiu Teodorescu, Simona Cavalu","doi":"10.22543/2392-7674.1401","DOIUrl":"https://doi.org/10.22543/2392-7674.1401","url":null,"abstract":"Objectives. The experience accumulated in the last two years shows that the prevention of COVID-19 in people with comorbidities (protective measures, vaccination, etc.) still remains a public health priority. In this context, the aim of our study was to perform a retrospective, observational study in order to assess the time-to-death and risk factors of mortality among COVID-19 patients. Materials and Methods. The study was conducted on 177 patients admitted to Oradea Emergency County Hospital, Bihor, Romania, between October and December 2021. Inclusion criteria were patients over 18 years positive for COVID-19 in upper respiratory tract samples using real-time PCR test. Exclusion criteria were pregnant women, ageyears, and patients with incomplete records at admission. Results. The mortality rate was assessed in correlation with the most prevalent comorbidities such as diabetes, cardiovascular diseases, hypertension, chronic kidney disease, and chronic pulmonary diseases, either alone or associated. During hospitalization, an aggravated health condition was noticed for 71 patients (40.11%). Among them, 47 patients were transferred to the intensive care unit (66.20%) due to severe respiratory failure, aggravation of associated diabetes and/or other associated comorbidities. Ventilation support was necessary in 122 cases (68.63%). The average survival time was 8.66 days. In conclusion, we found that the most prevalent comorbidities were cardiovascular diseases, being the major risk factor for mortality or aggravation after hospitalization. Its association with diabetes caused a risk of death 2.1 times higher than in patients without comorbidities. Based on Kaplan–Meier survival analysis, we found that the in-hospital survival rate was significantly higher in females compared to males (50.52% vs 33.75%).","PeriodicalId":43987,"journal":{"name":"Journal of Mind and Medical Sciences","volume":"1293 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135929123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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