Pub Date : 2021-05-21DOI: 10.1080/01947648.2021.1914482
Kim Thu Nguyen, N. Nguyen, W. Havins
Screen for Lysosomal Storage Diseases, Save More Nevada Babies Kim Thu Nguyen, OMS-II, knguyen38@student.touro.edu, Nguyen Nguyen, OMS-II, nnguyen20@student.touro.edu Weldon Havins, MD, JD, LLM, FCLM, Professor Emeritus Touro University Nevada College of Osteopathic Medicine, Henderson, NV. Introduction In the US, the Recommended Uniform Screening Panel (RUSP) currently endorses 29 disorders for which newborns should be screened, given evidence of the benefits of early detection. With increasing knowledge of disease progression, new and improved treatment options, and development of efficient screening tests, the screening of newborns for lysosomal storage disorders (LSD) has been quickly gaining momentum in the last decade. In 2019, Nevada passed Senate Bill 291, mandating the screening of all conditions in the RUSP, including Pompe disease and mucopolysaccharidosis I (MPS I). Currently, improved screening technology can measure enzymatic activities for several LSDs in a single analysis, allowing for the conservation of labor, equipment, samples, and reagents. The aim of this study is to evaluate the feasibility and cost-effectiveness of adding Fabry and Gaucher disease to Nevada’s newborn screening panel once screening for Pompe disease and MPS I has been established. Methods We performed a systematic review of literature to identify evidence on the natural history of Fabry and GD, as well as availability and effectiveness of treatment options and screening tests. We also compiled a list of costs associated with common clinical manifestations of Fabry and GD that commonly occur prior to diagnosis without an early detection program. We then compared these costs to the estimated costs of screening. Results We have estimated that the cost of adding on the screening of these two LSDs, once screening for Pompe and MPS I is established, will cost approximately $89,205 per year. The estimated costs of management of Fabry and GD in the absence of early detection and treatment are shown below: 2021 American College of Legal Medicine JOURNAL OF LEGAL MEDICINE 2021, VOL. 41, NO. S1, 29–30 https://doi.org/10.1080/01947648.2021.1914482
{"title":"Screen for Lysosomal Storage Diseases, Save More Nevada Babies","authors":"Kim Thu Nguyen, N. Nguyen, W. Havins","doi":"10.1080/01947648.2021.1914482","DOIUrl":"https://doi.org/10.1080/01947648.2021.1914482","url":null,"abstract":"Screen for Lysosomal Storage Diseases, Save More Nevada Babies Kim Thu Nguyen, OMS-II, knguyen38@student.touro.edu, Nguyen Nguyen, OMS-II, nnguyen20@student.touro.edu Weldon Havins, MD, JD, LLM, FCLM, Professor Emeritus Touro University Nevada College of Osteopathic Medicine, Henderson, NV. Introduction In the US, the Recommended Uniform Screening Panel (RUSP) currently endorses 29 disorders for which newborns should be screened, given evidence of the benefits of early detection. With increasing knowledge of disease progression, new and improved treatment options, and development of efficient screening tests, the screening of newborns for lysosomal storage disorders (LSD) has been quickly gaining momentum in the last decade. In 2019, Nevada passed Senate Bill 291, mandating the screening of all conditions in the RUSP, including Pompe disease and mucopolysaccharidosis I (MPS I). Currently, improved screening technology can measure enzymatic activities for several LSDs in a single analysis, allowing for the conservation of labor, equipment, samples, and reagents. The aim of this study is to evaluate the feasibility and cost-effectiveness of adding Fabry and Gaucher disease to Nevada’s newborn screening panel once screening for Pompe disease and MPS I has been established. Methods We performed a systematic review of literature to identify evidence on the natural history of Fabry and GD, as well as availability and effectiveness of treatment options and screening tests. We also compiled a list of costs associated with common clinical manifestations of Fabry and GD that commonly occur prior to diagnosis without an early detection program. We then compared these costs to the estimated costs of screening. Results We have estimated that the cost of adding on the screening of these two LSDs, once screening for Pompe and MPS I is established, will cost approximately $89,205 per year. The estimated costs of management of Fabry and GD in the absence of early detection and treatment are shown below: 2021 American College of Legal Medicine JOURNAL OF LEGAL MEDICINE 2021, VOL. 41, NO. S1, 29–30 https://doi.org/10.1080/01947648.2021.1914482","PeriodicalId":44014,"journal":{"name":"Journal of Legal Medicine","volume":"104 1","pages":"29 - 30"},"PeriodicalIF":0.4,"publicationDate":"2021-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80829756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-21DOI: 10.1080/01947648.2021.1914480
Summer Mostafa, Anjali Renukunta, W. Havins
{"title":"Banning Condoms as Evidence against Sex Workers in Illegal Prostitution","authors":"Summer Mostafa, Anjali Renukunta, W. Havins","doi":"10.1080/01947648.2021.1914480","DOIUrl":"https://doi.org/10.1080/01947648.2021.1914480","url":null,"abstract":"","PeriodicalId":44014,"journal":{"name":"Journal of Legal Medicine","volume":"36 1","pages":"26 - 26"},"PeriodicalIF":0.4,"publicationDate":"2021-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81287440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-21DOI: 10.1080/01947648.2021.1914472
R. Briggs, D. Hilton, Joseph P. Hardy, W. Havins
{"title":"The “Strawman” in the Process of Review and Evaluation of Complaints Regarding Controlled Substance Prescriptions","authors":"R. Briggs, D. Hilton, Joseph P. Hardy, W. Havins","doi":"10.1080/01947648.2021.1914472","DOIUrl":"https://doi.org/10.1080/01947648.2021.1914472","url":null,"abstract":"","PeriodicalId":44014,"journal":{"name":"Journal of Legal Medicine","volume":"12 1","pages":"9 - 10"},"PeriodicalIF":0.4,"publicationDate":"2021-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82298326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-21DOI: 10.1080/01947648.2021.1914474
Kenneth G. Denning, Omair Javaid, Joseph P. Hardy
COVID-19 has caused an unprecedented crisis globally In response, concern about the impact of stay-at-home orders on domestic violence have led to a consensus expecting a substantial increase in domestic violence The purpose of this study is to compare the amount of domestic violence calls made to southern Nevada police departments during April and May of the COVID-19 pandemic to the amount of calls received in the same months of the two previous years The data compares documented calls to three separate police departments--Las Vegas Metropolitan, North Las Vegas and Henderson--in Clark County in both April and May in 2018, 2019 and 2020 The calls collected in this study are based on specific call codes used by police departments to document calls relating to domestic violence, including domestic battery and family disturbance The results will be beneficial to better understanding the effects of crises on domestic violence and can inform policy regarding the response of law enforcement, healthcare professionals and others
{"title":"The Impact of COVID-19 Isolation on Domestic Violence Calls in Southern Nevada","authors":"Kenneth G. Denning, Omair Javaid, Joseph P. Hardy","doi":"10.1080/01947648.2021.1914474","DOIUrl":"https://doi.org/10.1080/01947648.2021.1914474","url":null,"abstract":"COVID-19 has caused an unprecedented crisis globally In response, concern about the impact of stay-at-home orders on domestic violence have led to a consensus expecting a substantial increase in domestic violence The purpose of this study is to compare the amount of domestic violence calls made to southern Nevada police departments during April and May of the COVID-19 pandemic to the amount of calls received in the same months of the two previous years The data compares documented calls to three separate police departments--Las Vegas Metropolitan, North Las Vegas and Henderson--in Clark County in both April and May in 2018, 2019 and 2020 The calls collected in this study are based on specific call codes used by police departments to document calls relating to domestic violence, including domestic battery and family disturbance The results will be beneficial to better understanding the effects of crises on domestic violence and can inform policy regarding the response of law enforcement, healthcare professionals and others","PeriodicalId":44014,"journal":{"name":"Journal of Legal Medicine","volume":"155 1","pages":"13 - 14"},"PeriodicalIF":0.4,"publicationDate":"2021-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77027928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-21DOI: 10.1080/01947648.2021.1914468
Varchita Alishetti, Siri Magadi, W. Havins
{"title":"Enact a Safe Firearm Storage Law to Reduce Suicides and Unintentional Deaths in Nevada","authors":"Varchita Alishetti, Siri Magadi, W. Havins","doi":"10.1080/01947648.2021.1914468","DOIUrl":"https://doi.org/10.1080/01947648.2021.1914468","url":null,"abstract":"","PeriodicalId":44014,"journal":{"name":"Journal of Legal Medicine","volume":"11 1","pages":"1 - 2"},"PeriodicalIF":0.4,"publicationDate":"2021-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74529088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-21DOI: 10.1080/01947648.2021.1914471
M. Bressler, Alisa O. Girard, S. Felice, Deborah Kiehlmeier, William Blazey, J. Zampella
IntroductionSocial media (SM) is rapidly evolving as a dominant force in disseminating health information —and misinformation. Physicians engaging online are faced with new ethical and legal challe...
{"title":"Ethical and Legal Issues for Medical Professionals Using Social Media","authors":"M. Bressler, Alisa O. Girard, S. Felice, Deborah Kiehlmeier, William Blazey, J. Zampella","doi":"10.1080/01947648.2021.1914471","DOIUrl":"https://doi.org/10.1080/01947648.2021.1914471","url":null,"abstract":"IntroductionSocial media (SM) is rapidly evolving as a dominant force in disseminating health information —and misinformation. Physicians engaging online are faced with new ethical and legal challe...","PeriodicalId":44014,"journal":{"name":"Journal of Legal Medicine","volume":"2 1","pages":"5 - 8"},"PeriodicalIF":0.4,"publicationDate":"2021-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83156949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1080/01947648.2021.1935634
Shuyu Zhong
{"title":"Take Away from COVID-19 Outbreak: Enhancing Jails' and Prisons' Abilities in Response to a Future Pandemic.","authors":"Shuyu Zhong","doi":"10.1080/01947648.2021.1935634","DOIUrl":"https://doi.org/10.1080/01947648.2021.1935634","url":null,"abstract":"","PeriodicalId":44014,"journal":{"name":"Journal of Legal Medicine","volume":"41 1-2","pages":"109-119"},"PeriodicalIF":0.4,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/01947648.2021.1935634","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39211978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1080/01947648.2021.1935632
Ellen Smith Yost
{"title":"Curbing a Stealth Health Threat: Regulation of Child-Directed \"Stealth\" Junk Food Marketing.","authors":"Ellen Smith Yost","doi":"10.1080/01947648.2021.1935632","DOIUrl":"https://doi.org/10.1080/01947648.2021.1935632","url":null,"abstract":"","PeriodicalId":44014,"journal":{"name":"Journal of Legal Medicine","volume":"41 1-2","pages":"83-93"},"PeriodicalIF":0.4,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/01947648.2021.1935632","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39211975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1080/01947648.2021.1919252
Norman L Cantor
Progressive dementia afflicts millions of people, ultimately entailing precipitous mental decline and years of complete dependence on others. Many people deem the prospect of serious cognitive dysfunction, helplessness, and dependence to be intolerably degrading (as well as overly burdensome on others). To avoid being mired in prolonged dementia, they prefer to hasten death by advance instructions rejecting life-sustaining medical intervention at a point of decline they define as unacceptable.Some health care providers resist implementation of such advance instructions, especially as applied to patients with dementia who are not ostensibly suffering in their demented states and no longer recall their prior instructions and the dignity concerns that underlay them. The clash between advance wishes to hasten death and some health care providers' preference to maintain the well-being of nonsuffering patients will be surfacing, in coming years, in institutional ethics committees, professional disciplinary forums, and the courts. This article defends the legal and moral status of advance instructions seeking to shorten the unwanted limbo of deep dementia.
{"title":"Dispelling Medico-Legal Misconceptions Impeding Use of Advance Instructions to Shorten Immersion in Deep Dementia.","authors":"Norman L Cantor","doi":"10.1080/01947648.2021.1919252","DOIUrl":"https://doi.org/10.1080/01947648.2021.1919252","url":null,"abstract":"<p><p>Progressive dementia afflicts millions of people, ultimately entailing precipitous mental decline and years of complete dependence on others. Many people deem the prospect of serious cognitive dysfunction, helplessness, and dependence to be intolerably degrading (as well as overly burdensome on others). To avoid being mired in prolonged dementia, they prefer to hasten death by advance instructions rejecting life-sustaining medical intervention at a point of decline they define as unacceptable.Some health care providers resist implementation of such advance instructions, especially as applied to patients with dementia who are not ostensibly suffering in their demented states and no longer recall their prior instructions and the dignity concerns that underlay them. The clash between advance wishes to hasten death and some health care providers' preference to maintain the well-being of nonsuffering patients will be surfacing, in coming years, in institutional ethics committees, professional disciplinary forums, and the courts. This article defends the legal and moral status of advance instructions seeking to shorten the unwanted limbo of deep dementia.</p>","PeriodicalId":44014,"journal":{"name":"Journal of Legal Medicine","volume":"41 1-2","pages":"29-46"},"PeriodicalIF":0.4,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/01947648.2021.1919252","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39211973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1080/01947648.2021.1929589
Jessica Bresler, Michael S Sinha
As the opioid crisis in the United States evolved, so did the relationship between prescribers and pharmaceutical companies that manufacture prescription opioids, with policymakers at both the state and national levels focused on the issue of prescription opioid misuse. This article discusses the role of the prescriber-pharmaceutical company relationship with respect to opioid over- and underprescribing, the evolution of that relationship over time, and its contribution to what is now commonly known as the U.S. opioid crisis or overdose epidemic. The United States saw several "waves" of prescription opioid misuse, and this article characterizes the relationship between prescribers and pharmaceutical companies in similar waves. The article proposes several prescriber- and manufacturer-focused "solutions" that can be implemented to address and lessen the effects of the ongoing crisis. Changes directed at prescribers and manufacturers must be implemented in tandem to ensure such solutions do not, in attempting to fill the existing cracks in the system, create even more.
{"title":"The Other Three Waves: Re-assessing the Impact of Industry-Prescriber Relations on the Opioid Crisis.","authors":"Jessica Bresler, Michael S Sinha","doi":"10.1080/01947648.2021.1929589","DOIUrl":"https://doi.org/10.1080/01947648.2021.1929589","url":null,"abstract":"<p><p>As the opioid crisis in the United States evolved, so did the relationship between prescribers and pharmaceutical companies that manufacture prescription opioids, with policymakers at both the state and national levels focused on the issue of prescription opioid misuse. This article discusses the role of the prescriber-pharmaceutical company relationship with respect to opioid over- and underprescribing, the evolution of that relationship over time, and its contribution to what is now commonly known as the U.S. opioid crisis or overdose epidemic. The United States saw several \"waves\" of prescription opioid misuse, and this article characterizes the relationship between prescribers and pharmaceutical companies in similar waves. The article proposes several prescriber- and manufacturer-focused \"solutions\" that can be implemented to address and lessen the effects of the ongoing crisis. Changes directed at prescribers <i>and</i> manufacturers must be implemented in tandem to ensure such solutions do not, in attempting to fill the existing cracks in the system, create even more.</p>","PeriodicalId":44014,"journal":{"name":"Journal of Legal Medicine","volume":"41 1-2","pages":"47-81"},"PeriodicalIF":0.4,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/01947648.2021.1929589","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39211972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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