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Investigating the Relationship Between Opioid Prescription Frequency and Deaths From Illicit Opioids 阿片类药物处方频率与非法阿片类药物死亡的关系研究
IF 0.4 4区 医学 Q3 LAW Pub Date : 2021-05-21 DOI: 10.1080/01947648.2021.1914493
C. Wyant, Taylor Cornwell-Hinrichs, Joseph P. Hardy, W. Havins
Investigating the Relationship Between Opioid Prescription Frequency and Deaths From Illicit Opioids Cara Wyant, OMS-II Taylor Cornwell-Hinrichs, MPH, MLIS, OMS-II Joseph P. Hardy, MD, Associate Dean of Clinical Education Weldon Havins, MD, JD, LLM, MA, Emeritus Professor Touro University Nevada College of Osteopathic Medicine In accordance with the global opioid epidemic, the CDC issued guidelines for practitioners prescribing opioids for chronic pain. In response to these guidelines and to the opioid epidemic itself, Nevada issued restrictive legislation on practitioners prescribing opioids: SB 459, AB 474, and AB 239. To investigate the relationships between opioid legislature and opioidrelated death rates, data was obtained from the Nevada Board of Pharmacy and the Clark and Washoe County medical examiner offices. The data demonstrate that there was a significant decrease in prescriptions following the legislation; however, there was no correlation between the legislation and overall rate of opioid-related deaths because there was a subsequent and dramatic rise in deaths from illicit opioids. This suggests that more patients switched to the use of heroin and/or fentanyl as a result in limiting legal opioid prescribing power. A Spearman correlation was calculated (-0.04) and a two-way analysis of variance (ANOVA) was used to compare the time periods of the legislation implementation and the county. There were no interactions between the two counties and law; so, both counties experienced the same trends following these laws. To compare opioid-related deaths to opioid prescription rate for each time period, a t-test with law as the only factor was conducted with combined data from both counties (SB 459 p1⁄4 0.744; AB 474 p1⁄4 0.640; AB 239 p1⁄4 0.704). No significance was found. The COVID-19 Stay at Home order has statistically increased opioid-related deaths (p1⁄4 0.010), albeit it is unknown if this increase is due to Nevadans selfmedicating in response to work stoppages and financial stress, inability to see a practitioner in person, or restrictions involving addiction clinics during the pandemic. The goal of Nevada’s three opioid prescription bills was to reduce the rate of Nevadans dying from opioid overdoses, yet more Nevadans are dying from opioids now than before the bills passed. We recommend three provisions that will allow providers to confidently prescribe appropriate 2021 American College of Legal Medicine JOURNAL OF LEGAL MEDICINE 2021, VOL. 41, NO. S1, 49–50 https://doi.org/10.1080/01947648.2021.1914493 pain management for their patients without fear of sanction from another licensing board’s misunderstandings, allow providers to humanely manage their patients’ legitimate pain, and limit unintended consequences where patients are forced to seek out illicit opioids to control their pain and inadvertently die in the process. These are our recommendations: (1) Base law requirements on guidelines provided by professional or governmen
调查阿片类药物处方频率与非法阿片类药物死亡之间的关系Cara Wyant, OMS-II Taylor Cornwell-Hinrichs, MPH, MLIS, OMS-II Joseph P. Hardy, MD,临床教育副院长Weldon Havins, MD, JD, LLM, MA, Touro University Nevada College of Osteopathic Medicine名誉教授根据全球阿片类药物流行,CDC发布了从业人员处方阿片类药物治疗慢性疼痛的指南。为了响应这些指导方针和阿片类药物的流行,内华达州颁布了关于开具阿片类药物处方的从业人员的限制性立法:SB 459、AB 474和AB 239。为了调查阿片类药物立法与阿片类药物相关死亡率之间的关系,从内华达州药房委员会以及克拉克和瓦肖县法医办公室获得了数据。数据表明,立法后处方显着减少;然而,立法与阿片类药物相关死亡率之间没有相关性,因为非法阿片类药物导致的死亡人数随后急剧上升。这表明,由于限制了阿片类药物的合法处方权,更多的患者转而使用海洛因和/或芬太尼。计算Spearman相关(-0.04),并采用双向方差分析(ANOVA)比较立法实施与县的时间段。这两个国家和法律之间没有互动;因此,这两个国家都经历了遵循这些法律的相同趋势。为了比较每个时间段阿片类药物相关死亡与阿片类药物处方率,对两县的合并数据进行了t检验,法律是唯一的因素(SB 459 p1⁄4 0.744;AB 474 p1 / 4 0.640;AB 239 p1 / 4 0.704)。没有发现显著性。2019冠状病毒病居家令在统计上增加了与阿片类药物相关的死亡人数(p1 / 4 0.010),尽管尚不清楚这一增加是由于内华达州人为应对停工和经济压力而自我用药、无法亲自去看医生,还是疫情期间涉及成瘾诊所的限制。内华达州三项阿片类药物处方法案的目标是降低内华达人因过量服用阿片类药物而死亡的比例,然而,与法案通过之前相比,现在死于阿片类药物的内华达人更多了。我们建议三条规定,使提供者能够自信地开出适当的2021年美国法律医学学院法律医学杂志2021年,第41卷,NO。S1, 49-50 https://doi.org/10.1080/01947648.2021.1914493对患者的疼痛管理,而不必担心另一个许可委员会的误解,允许提供者人道地管理患者的合法疼痛,并限制患者被迫寻求非法阿片类药物来控制疼痛并在此过程中无意中死亡的意外后果。以下是我们的建议:(1)以医学为导向的专业或政府机构提供的指导方针为基础的法律要求;(2)首先以教育为纪律,然后以制裁为纪律;(3)通过非常熟悉提供者执业范围的实体来执行要求,例如内华达州医学检验委员会和内华达州骨科医学委员会。应要求提供参考资料。50文摘
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引用次数: 0
Increased Deaths-at-Home in Nevada During the COVID-19 Pandemic 在COVID-19大流行期间,内华达州在家死亡人数增加
IF 0.4 4区 医学 Q3 LAW Pub Date : 2021-05-21 DOI: 10.1080/01947648.2021.1914479
Proma Mazumder, Crystal Yung, C. Vanier, Joseph P. Hardy
Indirect effects associated with forced or voluntary changes in behaviors due to COVID-19 are largely unknown Fear of COVID-19 infection may cause patients to avoid medical care for other conditions, and government directives have forced major lifestyle disruptions The purpose of this study was to analyze deaths at home (DaH) relative to gender, age, ethnicity, location, and cause of death to understand the indirect effects of COVID-19 on mortality rates in Nevada DaH increased 25% in Nevada during April 2020 (27 9;95% confidence interval: 26 3, 29 5 deaths per 100,000) compared to mean DaH during April the previous four years (22 3 mean deaths per 100,000) The increase was driven by males, people aged 65-74, and residents of the Las Vegas area There was no trend related to ethnicity Causes of death that increased in 2020 were diabetes mellitus (109%), nutritional deficiencies (860%), non-transport accidents (50%), and as-yet unknown causes (863%)
由于COVID-19而被迫或自愿改变行为的间接影响在很大程度上是未知的,对COVID-19感染的恐惧可能导致患者避免因其他疾病接受医疗护理,而政府指令已迫使重大生活方式中断。本研究的目的是分析与性别、年龄、种族、地点、2020年4月,内华达州DaH的COVID-19对死亡率的间接影响增加了25%(27 9;95%置信区间:与过去4年4月的平均死亡人数相比(每10万人中有223人死亡),死亡人数的增加是由男性、65-74岁的人以及拉斯维加斯地区的居民推动的,与种族无关。2020年死亡人数增加的原因是糖尿病(109%)、营养缺乏(860%)、非交通事故(50%)和尚未查明的原因(863%)。
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引用次数: 0
Nevada Healthcare Boards: Violations of Public Record Act and Inaccessibility of Licensee Information 内华达州医疗保健委员会:违反《公共记录法》和无法获取被许可人信息
IF 0.4 4区 医学 Q3 LAW Pub Date : 2021-05-21 DOI: 10.1080/01947648.2021.1914489
Ryliezl Abby Reyes, Stephanie Quan, Joseph P. Hardy, W. Havins
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引用次数: 0
Emerging Neuralink Brain Machine Interface Technology: An Oversight Proposal to Address the Ethical, Legal, and Social Implications 新兴的神经连接脑机接口技术:解决伦理、法律和社会影响的监督建议
IF 0.4 4区 医学 Q3 LAW Pub Date : 2021-05-21 DOI: 10.1080/01947648.2021.1914490
Ali Said, L. Sánchez, M. Olek, Weldon Havins
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引用次数: 0
Assessing the Relationship between Infection Citations and COVID-19 Infections in Nursing Homes 评估疗养院感染引文与COVID-19感染之间的关系
IF 0.4 4区 医学 Q3 LAW Pub Date : 2021-05-21 DOI: 10.1080/01947648.2021.1914478
Meghan Mahalawat, Nur Fatimah Mirza, C. Vanier, W. Havins
In the US, 40% of fatalities from COVID-19 have occurred in nursing homes Identifying warning signs of nursing homes with a higher chance of having COVID-19 cases and deaths can help target interventions to lower the overall spread and mortality associated with the disease The purpose of this study was to determine whether staff shortages, staff infections, or previous citations would affect the likelihood of cases of COVID-19 and associated deaths in nursing homes Data was obtained from the Center for Medicare and Medicaid Services' Nursing Home Compare Dataset and the COVID-19 Nursing Home Dataset for six western states for 03/01/2019 through 02/29/2020 States were heterogeneous and were analyzed independently of each other The relationship between staff-confirmed COVID-19 cases and resident cases was tested using a Fisher's exact test A logistic regression was used to model how prior citations and staff shortages affected the likelihood of cases and deaths, relative to the number of occupied beds per facility
在美国,40%的COVID-19死亡病例发生在养老院,识别出COVID-19病例和死亡几率较高的养老院的警告信号,有助于有针对性地采取干预措施,降低与该疾病相关的总体传播和死亡率。数据来自2019年3月1日至2020年2月29日西部六个州的医疗保险和医疗补助服务中心的养老院比较数据集和COVID-19养老院数据集。这些州是异质的,彼此独立分析。工作人员确诊的COVID-19病例和居民病例之间的关系使用Fisher精确检验a逻辑进行检验使用回归模型来模拟先前的引证和工作人员短缺如何影响病例和死亡的可能性,相对于每个设施占用的床位数量
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引用次数: 1
Decreasing Inmate Populations to Mitigate Effects of COVID-19 in State Prisons 减少囚犯人数以减轻州监狱中COVID-19的影响
IF 0.4 4区 医学 Q3 LAW Pub Date : 2021-05-21 DOI: 10.1080/01947648.2021.1914477
Seung Joon Hwang, M. Kim, W. Havins
With the spread of COVID-19 comes reports of rising outbreaks in prisons throughout the United States. On a national level, the Federal Bureau of Prisons (BOP) has modified operation guidel...
随着COVID-19的传播,有报道称美国各地监狱的疫情不断上升。在国家层面上,联邦监狱局(BOP)已经修改了操作指南…
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引用次数: 1
Proposal for Using Digital Tools in Mitigating a Pandemic: Lessons Learned from COVID-19 关于使用数字工具缓解大流行的建议:从COVID-19吸取的经验教训
IF 0.4 4区 医学 Q3 LAW Pub Date : 2021-05-21 DOI: 10.1080/01947648.2021.1914469
Stephanie N Bernardo, Kylie Zeng, W. Havins
BACKGROUND: Since the COVID-19 outbreak began in Wuhan China, countries across the world have been forced to take unprecedented measures to combat it. While some countries are still grappling with the COVID-19 pandemic, others have fared better and have established relative normalcy quickly. The rapid transmission rate of the virus has shown a greater need for efficient and technologically modern containment measures. The use of digital tools to facilitate strict containment measures in countries that have faired well against the COVID-19 pandemic has sparked both interest and controversy. OBJECTIVE: In this study, we compare the precautions taken against the spread of COVID-19, particularly the use of digital tools in contact tracing, and propose policies that could be utilized in the U.S. for future COVID-19 waves or pandemics. METHODS: COVID-19 death rates data were obtained from the European Center for Disease Prevention and Control (ECDC) accessed through the Our World in Data database, and were evaluated based on population size per 100,000 from December 31, 2019 to September 6, 2020. All policies and measures enacted were obtained from their respective governmental websites. RESULTS: We found a strong association between lower death rates per capita and countries that implemented early mask use and strict border control measures that included mandatory quarantine using digital tools. There is a significant difference in the number of deaths per 100,000 when comparing Taiwan, South Korea, and Singapore versus the U.S., Spain, and Italy. CONCLUSIONS: Based on our research, it is evident that early intervention with the use of digital tools has a strong correlation for containing COVID-19. Infection rates and subsequent deaths in Italy, Spain, and more specifically the U.S. could have been much lower with early mask use and, more importantly, timely border control measures utilizing modern digital tools. Thus, we propose that the U.S. execute the following national policies should a public health emergency be declared: (1) Immediately establish a National Command responsible for enacting strict mandatory guidelines enforced by federal and state governments, including national mask use. (2) Mandate civilian cooperation with health officials in contact tracing and quarantine orders. Incoming travelers to the U.S. and those quarantined will be required to download a contact tracing app. We acknowledge the countries we studied differ in their cultures, political systems, and reporting criteria for COVID-19 deaths. Further research may need to be conducted to address these limitations; however, we believe that the proposed policies could protect the American public.
背景:新冠肺炎疫情在中国武汉爆发以来,世界各国被迫采取前所未有的防控措施。虽然一些国家仍在与COVID-19大流行作斗争,但其他国家的情况较好,并迅速建立了相对正常的状态。该病毒的快速传播速度表明,更需要采取有效和技术现代化的遏制措施。在应对COVID-19大流行表现良好的国家,利用数字工具促进严格的控制措施既引发了兴趣,也引发了争议。目的:在本研究中,我们比较了针对COVID-19传播所采取的预防措施,特别是在接触者追踪中使用数字工具的情况,并提出了可在美国用于未来COVID-19浪潮或大流行的政策。方法:2019年12月31日至2020年9月6日,从欧洲疾病预防控制中心(ECDC)通过Our World in data数据库获取COVID-19死亡率数据,并根据每10万人的人口规模进行评估。所有制定的政策和措施均来自各自的政府网站。结果:我们发现,较低的人均死亡率与实施早期口罩使用和严格边境控制措施(包括使用数字工具强制隔离)的国家之间存在密切关联。台湾、韩国、新加坡与美国、西班牙、意大利相比,每10万人中死亡人数相差很大。结论:根据我们的研究,显然使用数字工具进行早期干预与遏制COVID-19具有很强的相关性。在意大利、西班牙,特别是美国,如果早期使用口罩,更重要的是,及时采取利用现代数字工具的边境控制措施,感染率和随后的死亡率本可以低得多。因此,我们建议美国在宣布公共卫生紧急情况时执行以下国家政策:(1)立即建立一个国家指挥部,负责制定由联邦和州政府执行的严格强制性指导方针,包括全国口罩使用。(2)在接触者追踪和检疫令方面与卫生官员进行民事合作。到美国的入境旅客和被隔离的人将被要求下载接触者追踪应用程序。我们承认,我们研究的国家在文化、政治制度和COVID-19死亡报告标准方面存在差异。可能需要进行进一步的研究来解决这些限制;然而,我们认为拟议的政策可以保护美国公众。
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引用次数: 12
COVID-19 and Firearms: Public Health Considerations 2019冠状病毒病与枪支:公共卫生考虑
IF 0.4 4区 医学 Q3 LAW Pub Date : 2021-05-21 DOI: 10.1080/01947648.2021.1914491
Emily Silver
COVID-19 and Firearms: Public Health Considerations Emily M. Silver, MA; esilver3@uchicago.edu Department of Psychology Integrative Neuroscience Program, The University of Chicago, IL The global SARS-CoV-2 (otherwise known as COVID-19) pandemic has wreaked havoc across the world, infected over 100 million people and resulted in the deaths of approximately 2 million people to date (1). The need for people to remain physically separated from one another to reduce the spread of disease has resulted in many public health, corporate, and government policy changes. One particularly troubling phenomenon has been the increase in the rates of deaths by firearm violence in the US in 2020 (2). The evolving literature has documented increases across a number of inter-related issues including mental health conditions (3), suicide rates (4), violence (5), and firearm purchases (6). It is of paramount importance to recognize these trends and discuss the implications regarding short-term and long-term effects as well as how they may affect the delivery of health services. Pandemic-related Increases: Firearms Firearms have been purchased at historic rates during the pandemic (Mannix et al). Firearm sales in March 2020 increased by 85% from the previous year (7), resulting in an estimated 2.1 million excess firearm sales (6). The recent surge in firearm purchases is likely linked at least in part to the pandemic, which has induced heightened states of uncertainty and anxiety. The pandemic is associated with increased worry about violence, both for oneself and others, as well as increased firearm acquisition and changes in practices related to storage of firearms, including unlocked storage (8,9). Intent to purchase a firearm in the next twelve months is associated with more severe anxiety specific to COVID-19 (10). Therefore, not only are sales of firearms increasing, but people may be buying them in reaction to fears resulting from the pandemic. Pandemic-related Increases: Mental Health Conditions Measures intended to limit the spread of the virus, such as city-wide lockdowns and social distancing policies, have also induced pervasive psychological distress (11). Social isolation and loneliness, known risk factors for depression 2021 American College of Legal Medicine JOURNAL OF LEGAL MEDICINE 2021, VOL. 41, NO. S1, 42–46 https://doi.org/10.1080/01947648.2021.1914491 and feelings of hopelessness, likely contribute to the prevalence of anxiety and depression (12). An analysis of depressive symptomology in the US found a 3fold increase during the COVID-19 pandemic as compared to before (13). The pandemic has also been associated with disruptions in sleep (11,14), substance abuse (11,15), and posttraumatic stress (16,17). Frontline health workers are at particular risk for an increase in anxiety and depression (18). Pandemic-related Increases: Suicide Increases in prevalence of psychopathology and mental health crises during the pandemic has brought on concerns abou
尽管人们普遍认为,精神健康诊断、咨询,甚至是针对精神健康状况的药物治疗,都使个人丧失了行医资格
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引用次数: 0
Should Healthcare Workers Treat COVID-19 Patients Despite the Inadequate Personal Protective Equipment? 医护人员是否应该在个人防护装备不足的情况下治疗COVID-19患者?
IF 0.4 4区 医学 Q3 LAW Pub Date : 2021-05-21 DOI: 10.1080/01947648.2021.1914485
J. Parra, Heerod Malekghassemi, Joseph P. Hardy, W. Havins
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引用次数: 0
Euthanasia Should Be Legalized in Nevada 安乐死应该在内华达州合法化
IF 0.4 4区 医学 Q3 LAW Pub Date : 2021-05-21 DOI: 10.1080/01947648.2021.1914484
Ellie Ok, Kristine Rosas, W. Havins
Euthanasia Should Be Legalized in Nevada Ellie Ok, MS, OMSII; eok@student.touro.edu Kristine Rosas, OMSII; krosas@student.touro.edu Weldon Havins, MD, JD, LLM, FCLM, Emeritus Professor Touro University Nevada College of Osteopathic Medicine Current palliative care option for terminally ill patients disregards the autonomy of patients in some cases. These patients may request euthanasia with the intent to make an autonomous decision and gain back some control that they have lost to the disease. As physicians, we should strive to understand the rationale behind the patient’s request of euthanasia to alleviate suffering and provide the most suitable care that preserves the patients’ dignity and autonomy. The purpose of our research is to propose the legalization of euthanasia in Nevada for terminal patients. To examine the legality and morality of euthanasia, we applied the four biomedical ethics principles (autonomy, justice, beneficence, and maleficence) to the use of this practice. The number of cases of euthanasia and Physician-Assisted Suicides (PAS) in Netherlands and Canada were analyzed. Reports of PAS cases in Canada were obtained from Regional Euthanasia Review Committees and Interim Reports. Individual statutes and numerous studies were reviewed to compare the qualifications and requirements of euthanasia and PAS in different countries. This study found that in countries where both euthanasia and PAS are legal, euthanasia occurs at a higher rate than PAS. In Netherlands, the incidence of euthanasia from 2002 and 2010 to 2018 was 1672, 2910, 5277, 5856, 6303, and 5898 whereas PAS was 184, 182, 208, 216, 250, and 212. In Canada, the occurrence of euthanasia from 2016 to 2018 was 503, 1960, and 2613 compared to four, one, and one PAS cases. Although euthanasia is illegal in the United States, patients showed higher support for euthanasia over PAS, finding euthanasia to be more acceptable (67%) than assisted suicide (33%). We carefully compared and studied the qualifications of euthanasia in other countries to propose our guidelines for Nevada. We acknowledge that there should be strict limitations and documentation of cases to limit its abuse. Further studies are needed to examine the validity of child euthanasia or other vulnerable populations. More 2021 American College of Legal Medicine JOURNAL OF LEGAL MEDICINE 2021, VOL. 41, NO. S1, 32–33 https://doi.org/10.1080/01947648.2021.1914484 training and education of medical professionals in palliative care is indicated. This research highlights and challenges the need for change in our current palliative care options to include euthanasia. References upon request 33
安乐死应在内华达州合法化Ellie Ok, MS, OMSII;eok@student.touro.edu克里斯汀·罗萨斯,OMSII;krosas@student.touro.edu Weldon hains, MD, JD, LLM, FCLM,内华达大学骨科医学院名誉教授,目前晚期患者的姑息治疗选择在某些情况下忽视了患者的自主权。这些病人请求安乐死的目的可能是为了做出自主的决定,并重新获得一些因疾病而失去的控制权。作为医生,我们应该努力理解病人要求安乐死背后的理由,以减轻痛苦,并提供最合适的护理,维护病人的尊严和自主权。我们的研究目的是提出在内华达州对晚期病人实施安乐死的合法化。为了检验安乐死的合法性和道德性,我们将四项生物医学伦理原则(自主、正义、有益和恶意)应用于这种做法的使用。分析了荷兰和加拿大安乐死和医生协助自杀(PAS)的病例数。加拿大PAS病例的报告来自区域安乐死审查委员会和中期报告。个别法规和大量的研究进行了审查,以比较安乐死和PAS在不同国家的资格和要求。这项研究发现,在安乐死和PAS都合法的国家,安乐死的发生率高于PAS。在荷兰,2002年和2010年至2018年的安乐死发生率分别为1672、2910、5277、5856、6303和5898,而PAS的发生率分别为184、182、208、216、250和212。在加拿大,2016年至2018年的安乐死案例分别为503例、1960例和2613例,而PAS案例分别为4例、1例和1例。尽管安乐死在美国是非法的,但患者对安乐死的支持度高于PAS,认为安乐死比协助自杀(33%)更容易接受(67%)。我们仔细比较和研究了其他国家的安乐死条件,并为内华达州提出了我们的指导方针。我们承认应该有严格的限制和案件记录,以限制其滥用。需要进一步的研究来检验儿童安乐死或其他弱势群体的有效性。更多2021美国法律医学学院法学杂志2021年第41卷第1期S1, 32-33 https://doi.org/10.1080/01947648.2021.1914484指出对医疗专业人员进行姑息治疗方面的培训和教育。这项研究强调并挑战了改变我们目前的姑息治疗选择的必要性,包括安乐死。参考资料33
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引用次数: 0
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