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Comparison of the rate of maxillary canine retraction with or without modified corticotomy facilitated orthodontic treatment 改良皮质切开术与不改良皮质切开术促进正畸治疗的上颌犬后缩率比较
Pub Date : 2021-06-25 DOI: 10.25259/jgoh_56_2020
M. Kokila, V. Pai, Siri Krishna, Gautham Kalladka, Shreyas Rajaram, Shivparasad Goankar
The aim of the study was to evaluate and compare the rate of maxillary canine retraction in cases with modified corticotomy versus without modified corticotomy. Clinical interventional study. Split mouth design was used.A sample size of ten patients and 20 sites were selected within the age group of 18–35 years following all criteria of the study. Before orthodontic leveling and alignment, upper first premolar extraction was carried out under local anesthesia. Pre-treatment OPG and IOPA were taken in relation to the maxillary canine and maxillary second premolar teeth. One extraction side was considered as the experimental site and contralateral side as control. Leveling and alignment were started with wire sequence. After modified corticotomy procedure, the canine retraction was started with 8 mm NiTi closed coil spring. The amount of tooth movement was recorded with the help of a Digital Vernier Caliper at an interval of 1 month till the completion of canine retraction.Paired t-test showed higher mean velocity of tooth movement in modified corticotomy side (1.07 ± 0.25) as compared to the conventional side (0.91 ± 0.24), (P < 0.001).The modified corticotomy technique serves as an effective treatment modality for adults seeking orthodontic treatment with increased rate of orthodontic canine retraction.
本研究的目的是评估和比较改良皮质切开术与未改良皮质切开术的上颌犬科后缩率。临床介入研究。采用裂口设计。根据研究的所有标准,在18-35岁年龄组中选择了10名患者和20个地点的样本量。矫正矫直前,在局部麻醉下拔除上颌第一前磨牙。术前对上颌犬牙和上颌第二前磨牙进行OPG和IOPA测定。取拔牙一侧作为实验部位,对侧作为对照。调平和对准开始与电线序列。改良皮质切开术后,用8毫米镍钛封闭线圈弹簧开始犬侧牵。在数字游标卡尺的帮助下,每隔1个月记录一次牙齿的移动量,直到完成犬的内收。配对t检验显示,改良侧的牙齿移动速度(1.07±0.25)高于常规侧(0.91±0.24),差异有统计学意义(P < 0.001)。改良皮质切开术作为一种有效的治疗方式,为成人寻求正畸治疗增加正畸犬后缩率。
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引用次数: 0
Protecting the Volunteering Healthcare Providers in COVID-19 from Secondary Nosocomial Infections 保护COVID-19志愿医疗保健提供者免受继发性医院感染
Pub Date : 2021-06-25 DOI: 10.25259/jgoh_10_2021
S. Balaji
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引用次数: 0
Knowledge about antibiotic resistance among dental students in Chengalpattu district, Tamil Nadu – A cross-sectional study 泰米尔纳德邦Chengalpattu地区牙科学生抗生素耐药性知识-一项横断面研究
Pub Date : 2021-06-25 DOI: 10.25259/jgoh_55_2020
K. Indrapriyadharshini, S. Vishnuprasad, J. Mahesh, H. Faizunisa
Antibiotic resistance is rising to dangerously high levels in all parts of the world. New resistance mechanism is emerging and spreading globally, threatening our ability to treat common infectious diseases. Dentists prescribe about 9–11% of all common antibiotics. The aim of this study was to assess the knowledge and attitude of antibiotic resistance among graduating dental students.A cross-sectional study was conducted among 294 participants between November 2019 and December 2019. A structured questionnaire consisting of 14 questions was administered to the dental students. Descriptive analysis of demographic variables was done and knowledge score and attitude score were performed using Kruskal–Wallis H test.About 85% of the participants suggested amoxicillin as the choice of antibiotic. Among the four domains suggesting the solution for antibiotic resistance, 48% of the final year students suggested avoiding self-medication as a solution, 34% of interns suggested avoiding over dosage, and 48% of the 3rd year students suggested completing the course of antibiotics. A majority of (87%) of the final year students suggested the usage of prophylactic antibiotics in patients with infective endocarditis. The difference in mean change in attitude scores among the groups was statistically significant (P = 0.028).The research showed variable levels of knowledge and attitude about antibiotic resistance among the students of different year of study. The study result insists the need to educate the dental students more regarding antibiotics and their proper use.
抗生素耐药性正在世界各地上升到危险的高水平。新的耐药机制正在出现并在全球蔓延,威胁到我们治疗常见传染病的能力。牙医开出的抗生素约占所有常用抗生素的9-11%。本研究旨在了解牙科毕业生对抗生素耐药的认知和态度。在2019年11月至2019年12月期间,对294名参与者进行了横断面研究。对牙科学生进行了一份包含14个问题的结构化问卷调查。对人口学变量进行描述性分析,采用Kruskal-Wallis H检验进行知识得分和态度得分。约85%的参与者建议阿莫西林作为抗生素的选择。在建议抗生素耐药性解决方案的四个领域中,48%的大四学生建议避免自我用药作为解决方案,34%的实习生建议避免过量用药,48%的大三学生建议完成抗生素疗程。大多数(87%)最后一年的学生建议对感染性心内膜炎患者使用预防性抗生素。两组间态度均变得分差异有统计学意义(P = 0.028)。研究显示,不同年级的学生对抗生素耐药性的认识和态度各不相同。研究结果表明,有必要对牙科学生进行更多关于抗生素及其正确使用的教育。
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引用次数: 0
Evaluation of genetic polymorphism of interleukin-1β (rs16944) in chronic and aggressive periodontitis in a group of the Bengali population of West Bengal, India 印度西孟加拉邦孟加拉人群慢性和侵袭性牙周炎患者白细胞介素-1β (rs16944)基因多态性的评估
Pub Date : 2021-06-25 DOI: 10.25259/jgoh_45_2020
Avishek Das, Ritam Kundu, A. Pal, Somen Bagchi
The genetic basis of periodontitis was demonstrated by formal genetic studies which were focused on a range of various candidate genes selected for their roles in the immune system like genes of the interleukins (ILs) which regulate the intensity of host immunity-inflammatory response. This regulation of host response may be associated with the genetic polymorphisms, specific single-nucleotide polymorphisms of the genes of various ILs. Interleukin-1 (IL-1) is a principal mediator of inflammatory responses acting on many cell types and is itself produced by many different cells, including macrophages, endothelial cells, B cells, fibroblasts, epithelial cells, astrocytes, and osteoblasts in response to microorganisms, bacterial toxins, and complement components. In the present study, an attempt has been made to explore the role of IL-1β-511 (rs16944) genetic polymorphism in chronic as well as aggressive periodontitis in a group of the Bengali population of West Bengal, India.A total of 88 Bengali patients of both sexes were recruited in this study and they were divided into three groups: Group A (chronic periodontitis group), Group B (aggressive periodontitis group), and Group C (healthy control). The clinical parameters taken into consideration in the assessment of chronic and aggressive periodontitis were plaque index, calculus index, gingival index, probing pocket depth (PPD), and clinical attachment loss (CAL). A 3 ml of peripheral venous blood was collected from each selected participant and transferred to 3% EDTA containing serum vial and stored at −20°C for DNA extraction. DNA extraction was performed by the phenol chloroform method and ethanol precipitation. Genotyping of extracting DNA samples was carried out for locus IL-1β-511 (rs16944) by real-time polymerase chain reaction. Hardy–Weinberg equilibrium was tested for the gene polymorphism and association between genotypes and cases was examined by odds ratio with 95% confidence interval (CI) and Chi-square analysis using R programming software. Allelic frequencies were calculated according to the number of different alleles observed and the total number of alleles examined. Statistical significance was defined as P < 0.05.On analysis of minor allele frequencies of total periodontitis cases and control, the results were found to be statistically insignificant with P = 0.9799. Minor allele frequency of overall periodontitis cases and controls was 0.405 and 0.403, respectively; the odds ratio was 1.008 and 95% CI ranges from 0.53 to 1.88.The present study suggested no association of single-nucleotide polymorphism of IL-1β-511 (rs16944) with total periodontitis cases (both chronic periodontitis and aggressive periodontitis) in the present study cohort.
牙周炎的遗传基础是通过正式的遗传学研究证明的,这些研究集中在一系列不同的候选基因上,这些基因被选中在免疫系统中发挥作用,如调节宿主免疫炎症反应强度的白细胞介素(il)的基因。这种对宿主反应的调控可能与各种il基因的遗传多态性、特异性单核苷酸多态性有关。白细胞介素-1 (IL-1)是炎症反应的主要介质,作用于许多细胞类型,它本身由许多不同的细胞产生,包括巨噬细胞、内皮细胞、B细胞、成纤维细胞、上皮细胞、星形胶质细胞和成骨细胞,以响应微生物、细菌毒素和补体成分。在目前的研究中,我们试图探索IL-1β-511 (rs16944)基因多态性在印度西孟加拉邦孟加拉人群中慢性和侵袭性牙周炎中的作用。本研究共招募88名孟加拉患者,男女皆可,并将其分为三组:A组(慢性牙周炎组)、B组(侵袭性牙周炎组)和C组(健康对照)。慢性和侵袭性牙周炎评估的临床参数包括菌斑指数、牙石指数、牙龈指数、探诊袋深度(PPD)和临床附着损失(CAL)。从每个选定的参与者身上采集3ml外周静脉血,转移到含有3% EDTA的血清瓶中,保存在- 20°C用于DNA提取。采用苯酚氯仿法和乙醇沉淀法提取DNA。采用实时聚合酶链反应对提取的DNA样本IL-1β-511 (rs16944)位点进行基因分型。采用R编程软件对基因多态性进行Hardy-Weinberg平衡检验,并采用95%置信区间(CI)优势比和卡方分析检验基因型与病例的相关性。根据观察到的不同等位基因数量和检测到的等位基因总数计算等位基因频率。P < 0.05为差异有统计学意义。总牙周炎病例与对照组的次要等位基因频率比较,P = 0.9799,差异无统计学意义。总体牙周炎病例和对照组的次要等位基因频率分别为0.405和0.403;优势比为1.008,95% CI为0.53 ~ 1.88。本研究表明,IL-1β-511 (rs16944)的单核苷酸多态性与本研究队列中牙周炎病例(包括慢性牙周炎和侵袭性牙周炎)无关。
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引用次数: 0
Hypothesis: Relationship between Coronavirus Disease-19 and Periodontal status 假设:冠状病毒病-19与牙周状况的关系
Pub Date : 2021-06-25 DOI: 10.25259/jgoh_38_2020
Shruti Ligade, Yogita Shah
Coronavirus disease 2019 (COVID-19) is a global pandemic affecting 185 countries and >18.8 million patients worldwide as of July 2020. COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-2) and majorly manifesting as a hypoxic condition in the affected patients. It has shown to multiply rapidly among patients showing other debilities, majorly hypertension, and diabetes mellitus. Periodontitis is defined as a multifactorial disease predominantly governed by microbial dysbiosis and having risk factors as the presence of systemic pathology, decline in immunity, and increased stress. Keeping these factors as a plausible threat for periodontitis, there can be a postulation made that periodontitis can act as a probable risk factor for COVID-19. Limited resources and novelty of the disease hold back any confirmation of the co-relation.
截至2020年7月,2019冠状病毒病(COVID-19)是一种全球性大流行病,影响185个国家,全球患者超过1880万。COVID-19是由严重急性呼吸综合征冠状病毒2型(SARS-2)引起的,主要表现为受感染患者的缺氧状态。在患有其他疾病的患者中,主要是高血压和糖尿病患者中,它的发病率迅速增加。牙周炎被定义为一种多因素疾病,主要由微生物生态失调控制,其危险因素包括全身性病理、免疫力下降和压力增加。将这些因素作为牙周炎的合理威胁,可以假设牙周炎可能是COVID-19的一个可能的危险因素。有限的资源和疾病的新颖性阻碍了任何相关关系的确认。
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引用次数: 0
Nanoparticles in caries prevention: A review 纳米颗粒在龋齿预防中的研究进展
Pub Date : 2021-06-25 DOI: 10.25259/jgoh_57_2020
B. Tejaswi, Vidya Gopal Sree, E. Sivapriya, D. Archana, A. PradeepKumar
Nanotechnology is the branch of engineering that uses molecular machines with precise structures that are less than or equal to 0.1 μm in size. The word nano denotes 10 to the power of minus nine or 1 billionth. Treatment options for dental caries have been extensively studied; among them, the role of nanoparticles is of recent interest. Nanoparticles have shown promising results in the field of caries prevention because of their unique physical, mechanical, and biological characteristics. Nanosized systems have distinctive properties due to their increased surface-to-volume ratio and increased bioavailability toward cells and tissues. Furthermore, improved surface area results in better mechanical interlocking of nanoparticles to the resin matrix. They prevent dental caries by antimicrobial, remineralizing, and anti-inflammatory mechanisms. Although many nanoparticles have been studied for their role in caries prevention, only a few materials which were extensively studied are included in this review.
纳米技术是利用小于或等于0.1 μm尺寸的精密结构的分子机器的工程学分支。nano这个词的意思是10的负90次方或十亿分之一。龋齿的治疗方案已被广泛研究;其中,纳米颗粒的作用是最近的兴趣。纳米颗粒由于其独特的物理、机械和生物学特性,在防治龋齿领域显示出良好的效果。纳米系统由于其增加的表面体积比和增加的细胞和组织的生物利用度而具有独特的特性。此外,表面积的提高导致纳米颗粒与树脂基体的机械联锁更好。它们通过抗菌、再矿化和抗炎机制来预防龋齿。虽然许多纳米颗粒在预防龋齿方面的作用已经被研究过,但在本文中只包括了少数被广泛研究的材料。
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引用次数: 2
Changing concepts and trends from dental amalgam to composites 从牙科汞合金到复合材料不断变化的概念和趋势
Pub Date : 2021-06-25 DOI: 10.25259/jgoh_21_2020
Sriganesh Anguswamy, K. Adeni
An increase in concern regarding the safety and inferior aesthetics of amalgam restorations in dentistry has resulted in a transition from amalgam to other alternative dental materials such as composite resins. This article would critically analyze both the materials and the need for this changeover by means of scientific literature.
由于对牙科中汞合金修复的安全性和低劣美学的关注增加,导致从汞合金到其他替代牙科材料(如复合树脂)的过渡。本文将以科学文献的方式批判性地分析这种转变的材料和必要性。
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引用次数: 0
Comparative evaluation of bond strength of three self-adhering flowable composites to sound and demineralized enamel – An in vitro study 三种自粘流动复合材料对健全和脱矿牙釉质粘结强度的比较评价-体外研究
Pub Date : 2021-06-25 DOI: 10.25259/jgoh_60_2020
Shrikanth Benjwal, M. Goswami, Aditya saxena, Reenu Sarah Kurien, A. Mushtaq
The purpose of this study was to determine bond strength of three self-adhering flowable composites.Mean tensile bond strength was measured in three groups – Group A – Constic, Group B – Dyad Flow, and Group C – Fusio Liquid Dentin on sound and demineralized primary teeth. Fracture pattern was studied using a stereomicroscope for each sample and in classified as adhesive, cohesive, or mixed fracture.Mean tensile bond strength in sound enamel of Group A (Constic) was found to be 10.79 + 4.24, Group B (Dyad Flow) was 10.30 + 4.63, and of Group C (Fusio Liquid Dentine) was 11.87 + 4.45. No significant difference was found between the three groups (f = 0.327 and P = 0.724). However, a significant difference was found with demineralized enamel in three groups. Constic and Dyad Flow exhibited adhesive fracture pattern in majority of samples on sound enamel, whereas Fusio Liquid Dentin had mixed fracture pattern. On demineralized enamel, Constic exhibited adhesive fracture pattern majorly, whereas Dyad flow demonstrated mixed pattern and Fusio Liquid Dentin had more of cohesive fractures.Constic, Dyad Flow, and Fusio Liquid Dentin can be used instead of conventional pit and fissure sealants or in small occlusal cavities in primary teeth as a single step material.
本研究的目的是确定三种自粘流动复合材料的结合强度。测定三组(A组- Constic, B组- Dyad Flow, C组- fususio Liquid)牙本质对正常乳牙和脱矿乳牙的平均抗拉强度。在体视显微镜下对每个样品的断裂模式进行了研究,并将其分类为粘连性、内聚性或混合性断裂。A组(Constic)正常牙釉质平均抗拉强度为10.79 + 4.24,B组(Dyad Flow)平均抗拉强度为10.30 + 4.63,C组(fuso Liquid dentiine)平均抗拉强度为11.87 + 4.45。三组间差异无统计学意义(f = 0.327, P = 0.724)。然而,三组在脱矿牙釉质方面存在显著差异。在正常牙釉质上,Constic和Dyad Flow牙釉质多数呈粘连型断裂,而Fusio Liquid牙釉质多数呈混合型断裂。在脱矿牙釉质上,Constic牙釉质以粘连型为主,而Dyad flow牙釉质以混合型为主,Fusio Liquid牙釉质以粘连型为主。Constic, Dyad Flow和Fusio Liquid牙本质可以代替传统的坑状和裂隙密封剂,或者作为一种单步材料用于初级牙齿的小咬合腔。
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引用次数: 0
Assessment of oral health-related quality of life among head-and-neck cancer patients attending cancer care center at Kanchipuram, Tamil Nadu – A cross-sectional study 泰米尔纳德邦坎奇普兰癌症护理中心头颈癌患者口腔健康相关生活质量评估——一项横断面研究
Pub Date : 2021-06-25 DOI: 10.25259/jgoh_47_2020
Sekar Aswini, Girish R. Shavi, Sathyanarayan Muthur Shankar, R. Sanga, G. Lalithambigai, C. Rahila, S. Santhakumari
Oral health is closely related to general health and people’s quality of life (QoL), through affecting their oral functions and social interactions. This study aims to assess the oral health-related QoL among head-and-neck cancer (HNC) patients attending cancer care center at Kanchipuram, Tamil Nadu.A cross-sectional questionnaire-based study was conducted among 340 HNC patients between August and October 2019 attending Government Arignar Anna Memorial Cancer Hospital and Research Institute in Kanchipuram District of Tamil Nadu. The questionnaire has two parts. The 1st part consists of demographic characteristics and cancer-related details. The 2nd part was the European Organization of Research and Treatment of Cancer QoL in HNC patients (EORTC QLQ H&N-35) questionnaire.Among 340 patients, 72.4% were male and 27.6% were female. The majority of them had Stage II cancer. The main factors affecting oral health related QoL (OHRQoL) were taking painkillers, loss of sexual interest, difficulty in social contact, teeth problems, loss of taste, and smell senses. Significant association found between pain (P = 0.000), sense (P = 0.003), speech (P = 0.000), social eating (P = 0.016), social contact (P = 0.005), teeth problems (P = 0.031), dry mouth (P = 0.000), sticky saliva (P = 0.000), cough (0.002), feeling ill (P = 0.003), nutritional supplement (P = 0.042), and lost weight (P = 0.034) with respect to various treatment modalities. Based on the OHRQoL scores, those who were treated surgically alone had better QoL than others.We found that surgically treated HNC patients had better OHRQoL than others. Thus, Oral-Health related Quality of Life assessment can be used to analyse the outcome of treatment, patient satisfaction and their sense of self. We need to build a broader care protocol which satisfies/improves the demands arising from the patients.
口腔健康通过影响人们的口腔功能和社会交往,与总体健康和人们的生活质量密切相关。本研究旨在评估在泰米尔纳德邦坎奇普兰癌症护理中心就诊的头颈癌(HNC)患者口腔健康相关生活质量。2019年8月至10月,在泰米尔纳德邦坎奇普兰区政府阿里纳尔·安娜纪念癌症医院和研究所的340名HNC患者中进行了一项基于横断面问卷的研究。问卷分为两部分。第一部分包括人口统计学特征和癌症相关细节。第二部分为欧洲HNC患者癌症生活质量研究与治疗组织(EORTC QLQ H&N-35)问卷。340例患者中男性占72.4%,女性占27.6%。他们中的大多数都是II期癌症。影响口腔健康相关生活质量(OHRQoL)的主要因素是服用止痛药、性兴趣丧失、社交困难、牙齿问题、味觉和嗅觉丧失。疼痛(P = 0.000)、感觉(P = 0.003)、言语(P = 0.000)、社交饮食(P = 0.016)、社交接触(P = 0.005)、牙齿问题(P = 0.031)、口干(P = 0.000)、唾液粘粘(P = 0.000)、咳嗽(0.002)、感觉不舒服(P = 0.003)、营养补充(P = 0.042)和体重减轻(P = 0.034)与各种治疗方式之间存在显著关联。根据OHRQoL评分,单独接受手术治疗的患者比其他人的生活质量更好。我们发现手术治疗的HNC患者的OHRQoL优于其他患者。因此,与口腔健康相关的生活质量评估可用于分析治疗结果、患者满意度和自我意识。我们需要建立一个更广泛的护理方案,以满足/改善病人的需求。
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引用次数: 0
Oral health status of children in rural communities of Sri Lanka 斯里兰卡农村社区儿童口腔健康状况
Pub Date : 2021-06-25 DOI: 10.25259/jgoh_52_2020
Oariona Lowe, Dawn McClellan
Social determinants of health are affected by socioeconomic status, level of education attained, living conditions, and access to healthcare. Access to oral health care is impacted by the environment, in which one resides and the knowledge and benefits of good oral healthcare and prevention, most of which is influenced by parental knowledge and habits. Oral health status was reported on two populations of Sri Lankan children; one group residing in a tea plantation and the other in Mullaithivu, the northernmost area of Sri Lanka. Tea estate dwellers represent an impoverished group, where the education level attained is less than half of the national average. The decay rate in this population of children is high, many of them with early childhood caries. In Mullaithivu, children make up one-third of the population. Children between the ages of 6 and 19 were observed to have a large number of caries. Access to dental care in these remote areas is limited. Developing an oral health program to serve these populations would be beneficial to assist in healthy living.
健康的社会决定因素受到社会经济地位、受教育程度、生活条件和获得保健的机会的影响。获得口腔保健的机会受到人们所处环境以及良好口腔保健和预防的知识和益处的影响,其中大部分受父母的知识和习惯的影响。报告了两个斯里兰卡儿童群体的口腔健康状况;一组居住在茶园,另一组居住在斯里兰卡最北部的Mullaithivu。茶园居民是一个贫困群体,受教育程度不到全国平均水平的一半。这些儿童的龋齿率很高,其中许多患有幼儿期龋齿。在Mullaithivu,儿童占人口的三分之一。6至19岁的儿童被观察到有大量的龋齿。在这些偏远地区获得牙科保健的机会有限。为这些人群制定口腔健康计划将有助于他们的健康生活。
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引用次数: 0
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Journal of Global Oral Health
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