Pub Date : 2025-08-14DOI: 10.3390/audiolres15040108
Amanda Saksida, Marta Fantoni, Sara Ghiselli, Eva Orzan
Background: Ear advantage (EA) reflects hemispheric asymmetries in auditory processing. While a right-ear advantage (REA) for speech and a left-ear advantage (LEA) for music are well documented in typically developing individuals, it is unclear how these patterns manifest in young children with cochlear implants (CIs). This study investigated whether pupillometry could reveal asymmetric listening efforts in toddlers with bilateral CIs when listening to speech and music under monaural stimulation. Methods: Thirteen toddlers (mean age = 36.2 months) with early bilateral CIs participated. Pupillary responses were recorded during passive listening to speech and music stimuli, presented in quiet or with background noise. Each child was tested twice, once with only the left CI active and once with only the right CI active. Linear mixed-effects models assessed the influence of session (left/right CI), signal type (speech/music), and background noise. Results: A significant interaction between session and signal type was observed (p = 0.047). Speech elicited larger pupil sizes when processed through the left CI, while music showed no significant lateralized effects. Age and speech therapy frequency moderated pupil responses in speech and music trials, respectively. Conclusions: Pupillometry reveals subtle asymmetric listening effort in young CI users depending on the listening ear, suggesting early emerging functional lateralization despite sensory deprivation and device-mediated hearing.
{"title":"Is Pupil Response to Speech and Music in Toddlers with Cochlear Implants Asymmetric?","authors":"Amanda Saksida, Marta Fantoni, Sara Ghiselli, Eva Orzan","doi":"10.3390/audiolres15040108","DOIUrl":"10.3390/audiolres15040108","url":null,"abstract":"<p><p><b>Background:</b> Ear advantage (EA) reflects hemispheric asymmetries in auditory processing. While a right-ear advantage (REA) for speech and a left-ear advantage (LEA) for music are well documented in typically developing individuals, it is unclear how these patterns manifest in young children with cochlear implants (CIs). This study investigated whether pupillometry could reveal asymmetric listening efforts in toddlers with bilateral CIs when listening to speech and music under monaural stimulation. <b>Methods:</b> Thirteen toddlers (mean age = 36.2 months) with early bilateral CIs participated. Pupillary responses were recorded during passive listening to speech and music stimuli, presented in quiet or with background noise. Each child was tested twice, once with only the left CI active and once with only the right CI active. Linear mixed-effects models assessed the influence of session (left/right CI), signal type (speech/music), and background noise. <b>Results:</b> A significant interaction between session and signal type was observed (<i>p</i> = 0.047). Speech elicited larger pupil sizes when processed through the left CI, while music showed no significant lateralized effects. Age and speech therapy frequency moderated pupil responses in speech and music trials, respectively. <b>Conclusions:</b> Pupillometry reveals subtle asymmetric listening effort in young CI users depending on the listening ear, suggesting early emerging functional lateralization despite sensory deprivation and device-mediated hearing.</p>","PeriodicalId":44133,"journal":{"name":"Audiology Research","volume":"15 4","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12382946/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-13DOI: 10.3390/audiolres15040107
George Psillas, Petros D Karkos
We are pleased to present a Special Issue addressing new insights into the causes, symptoms, diagnosis, and treatment of hearing loss [...].
我们很高兴地提出一个特别问题,探讨听力损失的原因,症状,诊断和治疗的新见解[…]。
{"title":"Clinical Insights into Hearing Loss.","authors":"George Psillas, Petros D Karkos","doi":"10.3390/audiolres15040107","DOIUrl":"10.3390/audiolres15040107","url":null,"abstract":"<p><p>We are pleased to present a Special Issue addressing new insights into the causes, symptoms, diagnosis, and treatment of hearing loss [...].</p>","PeriodicalId":44133,"journal":{"name":"Audiology Research","volume":"15 4","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12382701/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-12DOI: 10.3390/audiolres15040105
Ambra Fastelli, Giulia Clignon, Daniele Corasaniti, Eva Orzan
Background/Objectives: Poor classroom acoustics and inadequate digital environments in educational settings can pose an additional barrier for students, especially those with special needs, such as students with hearing difficulties. These challenges can hinder communication, academic achievement, and social inclusion. Speech-to-text captioning systems offer a promising assistive tool to support education. This study aimed to evaluate the strengths and limitations of implementing such systems in schools through a structured strategic analysis. Methods: The analysis method consisted of two phases. A SWOT (Strengths, Weaknesses, Opportunities, Threats) analysis was performed on data from a survey compiled by an interdisciplinary team. A subsequent TOWS analysis was used to develop strategic recommendations by cross-referencing internal and external factors. Results: The analysis highlighted key strengths, including improved communication, support for inclusive practices, and adaptability to diverse learning needs. Identified weaknesses included cognitive load, synchronization delays, and variability in student profiles. Opportunities included educational innovation, access to funding programs, and interdisciplinary collaboration. Threats included inadequate classroom technology, poor acoustics, and the risks of social stigma. The analysis yielded 17 recommendations to improve the usability and customization of the tool. Conclusions: Speech-to-text captioning systems have significant potential to promote accessibility and inclusion in education. This strategic analysis provides a structured, interdisciplinary approach to strategic planning and the successful implementation of assistive technology in schools. By combining multidisciplinary expertise with structured evaluation, it identified key design, training, and policy priorities. This approach offers a replicable model for user-centered planning and the development of assistive tools and can inform wider efforts to reduce communication barriers in inclusive education.
{"title":"Speech-to-Text Captioning and Subtitling in Schools: The Results of a SWOT Analysis.","authors":"Ambra Fastelli, Giulia Clignon, Daniele Corasaniti, Eva Orzan","doi":"10.3390/audiolres15040105","DOIUrl":"10.3390/audiolres15040105","url":null,"abstract":"<p><p><b>Background/Objectives:</b> Poor classroom acoustics and inadequate digital environments in educational settings can pose an additional barrier for students, especially those with special needs, such as students with hearing difficulties. These challenges can hinder communication, academic achievement, and social inclusion. Speech-to-text captioning systems offer a promising assistive tool to support education. This study aimed to evaluate the strengths and limitations of implementing such systems in schools through a structured strategic analysis. <b>Methods:</b> The analysis method consisted of two phases. A SWOT (Strengths, Weaknesses, Opportunities, Threats) analysis was performed on data from a survey compiled by an interdisciplinary team. A subsequent TOWS analysis was used to develop strategic recommendations by cross-referencing internal and external factors. <b>Results:</b> The analysis highlighted key strengths, including improved communication, support for inclusive practices, and adaptability to diverse learning needs. Identified weaknesses included cognitive load, synchronization delays, and variability in student profiles. Opportunities included educational innovation, access to funding programs, and interdisciplinary collaboration. Threats included inadequate classroom technology, poor acoustics, and the risks of social stigma. The analysis yielded 17 recommendations to improve the usability and customization of the tool. <b>Conclusions:</b> Speech-to-text captioning systems have significant potential to promote accessibility and inclusion in education. This strategic analysis provides a structured, interdisciplinary approach to strategic planning and the successful implementation of assistive technology in schools. By combining multidisciplinary expertise with structured evaluation, it identified key design, training, and policy priorities. This approach offers a replicable model for user-centered planning and the development of assistive tools and can inform wider efforts to reduce communication barriers in inclusive education.</p>","PeriodicalId":44133,"journal":{"name":"Audiology Research","volume":"15 4","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12382921/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-12DOI: 10.3390/audiolres15040106
José Ramos-Rojas, Gonzalo Valdivia, Dominique Terán-Tapia, Anthony Marcotti, Eduardo Fuentes-López
Background/Objectives: Few studies have examined the relationship between hearing aid use and physical activity levels, yielding inconsistent results. The aim of this study was to determine the possible association between hearing aid use and physical activity levels in a representative sample of older adults with hearing loss and a clinical indication for hearing aid use in Chile. Methods: We conducted a cross-sectional analysis of data from a nationally representative health survey employing geographically stratified, multistage probability sampling. Participants were aged ≥60, had medical indication for hearing aid use, demonstrated normal cognitive function, and reported no motor disability. Physical activity was assessed using the Global Physical Activity Questionnaire (GPAQ). We also collected data on self-perceived hearing status, specialist recommendations for hearing aid use, and adherence among device owners. Multivariate ordinal regression models evaluated the association between hearing aid use and physical activity, accounting for the survey's complex sampling design. Results: The sample comprised 356 individuals, representing 599,912 older adults after applying survey weights. Overall, 50.5% reported owning a hearing aid; of these, 46.8% always used their device, and 19.1% never used it. Compared with consistent users, participants who used their hearing aid "sometimes" or "rarely" had significantly lower odds of higher physical activity levels (OR = 0.13; 95% CI: 0.02-0.85; p = 0.03 and OR = 0.13; 95% CI: 0.02-0.96; p = 0.04, respectively). Those who never used their hearing aid had 86% lower odds of higher physical activity (OR = 0.16; 95% CI: 0.03-0.94; p = 0.04). Conclusions: Consistent hearing aid use was associated with higher physical activity levels in older adults with hearing loss. These findings support the integration of hearing rehabilitation into broader strategies for promoting healthy aging.
背景/目的:很少有研究调查助听器使用与身体活动水平之间的关系,结果不一致。本研究的目的是确定助听器使用和身体活动水平之间的可能联系,在智利有听力损失的老年人的代表性样本和助听器使用的临床指征。方法:我们对一项具有全国代表性的健康调查数据进行了横断面分析,采用地理分层、多阶段概率抽样。参与者年龄≥60岁,有使用助听器的医学指征,表现出正常的认知功能,无运动障碍。使用全球身体活动问卷(GPAQ)评估身体活动。我们还收集了有关自我感知听力状况、助听器使用专家建议以及助听器使用者依从性的数据。多元有序回归模型评估了助听器使用和身体活动之间的关系,考虑到调查的复杂抽样设计。结果:样本包括356个人,在应用调查权重后代表599,912名老年人。总体而言,50.5%的人表示拥有助听器;其中46.8%的人经常使用手机,19.1%的人从不使用手机。与一贯使用助听器的人相比,“有时”或“很少”使用助听器的人出现高体力活动水平的几率明显较低(or = 0.13; 95% CI: 0.02-0.85; p = 0.03和or = 0.13; 95% CI: 0.02-0.96; p = 0.04)。那些从不使用助听器的人有86%的低几率增加体力活动(OR = 0.16; 95% CI: 0.03-0.94; p = 0.04)。结论:在听力损失的老年人中,持续使用助听器与较高的身体活动水平有关。这些发现支持将听力康复纳入促进健康老龄化的更广泛策略。
{"title":"Association Between Hearing Aid Use and Physical Activity Levels in Older Adults with Hearing Loss.","authors":"José Ramos-Rojas, Gonzalo Valdivia, Dominique Terán-Tapia, Anthony Marcotti, Eduardo Fuentes-López","doi":"10.3390/audiolres15040106","DOIUrl":"10.3390/audiolres15040106","url":null,"abstract":"<p><p><b>Background/Objectives:</b> Few studies have examined the relationship between hearing aid use and physical activity levels, yielding inconsistent results. The aim of this study was to determine the possible association between hearing aid use and physical activity levels in a representative sample of older adults with hearing loss and a clinical indication for hearing aid use in Chile. <b>Methods</b>: We conducted a cross-sectional analysis of data from a nationally representative health survey employing geographically stratified, multistage probability sampling. Participants were aged ≥60, had medical indication for hearing aid use, demonstrated normal cognitive function, and reported no motor disability. Physical activity was assessed using the Global Physical Activity Questionnaire (GPAQ). We also collected data on self-perceived hearing status, specialist recommendations for hearing aid use, and adherence among device owners. Multivariate ordinal regression models evaluated the association between hearing aid use and physical activity, accounting for the survey's complex sampling design. <b>Results:</b> The sample comprised 356 individuals, representing 599,912 older adults after applying survey weights. Overall, 50.5% reported owning a hearing aid; of these, 46.8% always used their device, and 19.1% never used it. Compared with consistent users, participants who used their hearing aid \"sometimes\" or \"rarely\" had significantly lower odds of higher physical activity levels (OR = 0.13; 95% CI: 0.02-0.85; <i>p</i> = 0.03 and OR = 0.13; 95% CI: 0.02-0.96; <i>p</i> = 0.04, respectively). Those who never used their hearing aid had 86% lower odds of higher physical activity (OR = 0.16; 95% CI: 0.03-0.94; <i>p</i> = 0.04). <b>Conclusions</b>: Consistent hearing aid use was associated with higher physical activity levels in older adults with hearing loss. These findings support the integration of hearing rehabilitation into broader strategies for promoting healthy aging.</p>","PeriodicalId":44133,"journal":{"name":"Audiology Research","volume":"15 4","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12382805/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-11DOI: 10.3390/audiolres15040103
Samuel R Atcherson, Evan T Finley, Jeanne Hahne
Background: Face masks are used in healthcare for the prevention of the spread of disease; however, the recent COVID-19 pandemic raised awareness of the challenges of typical opaque masks that obscure nonverbal cues. In addition, various masks have been shown to attenuate speech above 1000 Hz, and lack of nonverbal cues exacerbates speech understanding in the presence of background noise. Transparent masks can help to overcome the loss of nonverbal cues, but they have greater attenuative effects on higher speech frequencies. This study evaluated a newer prototype transparent face mask redesigned from a version evaluated in a previous study. Methods: Thirty participants (10 with normal hearing, 10 with moderate hearing loss, and 10 with severe-to-profound hearing loss) were recruited. Selected lists from the Connected Speech Test (CST) were digitally recorded using male and female talkers and presented to listeners at 65 dB HL in 12 conditions against a background of 4-talker babble (+5 dB SNR): without a mask (auditory only and audiovisual), with an opaque mask (auditory only and audiovisual), and with a transparent mask (auditory only and audiovisual). Results: Listeners with normal hearing performed consistently well across all conditions. For listeners with hearing loss, speech was generally easier to understand with the male talker. Audiovisual conditions were better than auditory-only conditions, and No Mask and Transparent Mask conditions were better than Opaque Mask conditions. Conclusions: These findings continue to support the use of transparent masks to improve communication, minimize medical errors, and increase patient satisfaction.
背景:口罩在医疗保健中用于预防疾病传播;然而,最近的COVID-19大流行提高了人们对典型的不透明口罩的挑战的认识,这种口罩会掩盖非语言信号。此外,各种面具已被证明会减弱1000赫兹以上的语音,并且缺乏非语言线索会加剧背景噪音存在下的语音理解。透明面具可以帮助克服非语言线索的丢失,但它们对较高的语音频率有更大的衰减作用。本研究评估了一种新的透明面罩原型,该原型是根据先前研究中评估的版本重新设计的。方法:招募30名受试者,其中听力正常者10名,中度听力损失者10名,重度至重度听力损失者10名。从连接语音测试(CST)中选择的列表使用男性和女性说话者进行数字记录,并在12种条件下以65 dB HL呈现给听众,背景为4-说话者胡言乱语(+5 dB信噪比):无掩模(仅听觉和视听),不透明掩模(仅听觉和视听),透明掩模(仅听觉和视听)。结果:听力正常的听众在所有条件下都表现良好。对于听力受损的听众来说,男性说话者的话语通常更容易被理解。视听条件优于纯听觉条件,无遮罩和透明遮罩条件优于不透明遮罩条件。结论:这些发现继续支持使用透明口罩改善沟通,减少医疗差错,提高患者满意度。
{"title":"Comparison of Prototype Transparent Mask, Opaque Mask, and No Mask on Speech Understanding in Noise.","authors":"Samuel R Atcherson, Evan T Finley, Jeanne Hahne","doi":"10.3390/audiolres15040103","DOIUrl":"10.3390/audiolres15040103","url":null,"abstract":"<p><p><b>Background:</b> Face masks are used in healthcare for the prevention of the spread of disease; however, the recent COVID-19 pandemic raised awareness of the challenges of typical opaque masks that obscure nonverbal cues. In addition, various masks have been shown to attenuate speech above 1000 Hz, and lack of nonverbal cues exacerbates speech understanding in the presence of background noise. Transparent masks can help to overcome the loss of nonverbal cues, but they have greater attenuative effects on higher speech frequencies. This study evaluated a newer prototype transparent face mask redesigned from a version evaluated in a previous study. <b>Methods:</b> Thirty participants (10 with normal hearing, 10 with moderate hearing loss, and 10 with severe-to-profound hearing loss) were recruited. Selected lists from the Connected Speech Test (CST) were digitally recorded using male and female talkers and presented to listeners at 65 dB HL in 12 conditions against a background of 4-talker babble (+5 dB SNR): without a mask (auditory only and audiovisual), with an opaque mask (auditory only and audiovisual), and with a transparent mask (auditory only and audiovisual). <b>Results:</b> Listeners with normal hearing performed consistently well across all conditions. For listeners with hearing loss, speech was generally easier to understand with the male talker. Audiovisual conditions were better than auditory-only conditions, and No Mask and Transparent Mask conditions were better than Opaque Mask conditions. <b>Conclusions:</b> These findings continue to support the use of transparent masks to improve communication, minimize medical errors, and increase patient satisfaction.</p>","PeriodicalId":44133,"journal":{"name":"Audiology Research","volume":"15 4","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12382911/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background/Objectives: Preschool hearing screening is justified by the risk of late onset hearing loss, the high prevalence of otitis media with effusion in school-aged children, and the critical timing just before children begin formal reading and learn to write. This study describes the results of the annual preschool hearing screening program in Campo Maior from 2007 to 2025 (nineteen years) and correlates the audiological referral to the otoscopy findings by the otolaryngologists. Methodology: Retrospective study using clinical records from nineteen years of preschool hearing screening. Results: Screening identified 310 children (29% of 1068 screened) requiring referral to an ENT specialist. Of the 217 referred children evaluated by ENT, 198 (91.2%) had confirmed pathology or healthcare needs of medical intervention. A statistically significant positive association (r = 0.254, p < 0.05) existed between abnormal otoscopy findings and Type B or C2 tympanograms (versus Type A or C1). Hearing loss occurring with Type A tympanograms (0.8% unilaterally, 0.3% bilaterally) may suggest sensorineural hearing loss. Conclusion: This study reinforces the importance of universal preschool audiological screening for all children, particularly for children facing geographic barriers to healthcare. Community-based interventions facilitated by social solidarity associations can play a crucial role in mitigating healthcare access disparities across populations.
背景/目的:学龄前听力筛查是合理的,因为有晚发性听力损失的风险,学龄儿童中耳炎伴渗出性中耳炎的高患病率,以及儿童开始正式阅读和学习写作之前的关键时间。本研究描述了2007年至2025年(19年)Campo Maior年度学龄前听力筛查计划的结果,并将听力学转诊与耳鼻喉科医生的耳镜检查结果联系起来。方法:回顾性研究使用十九年学龄前听力筛查的临床记录。结果:筛查确定310名儿童(占1068名筛查儿童的29%)需要转介给耳鼻喉科专家。在217名经耳鼻喉科评估的转诊儿童中,198名(91.2%)证实有病理或医疗干预的保健需求。耳镜检查异常与B型或C2型鼓室图(与A型或C1型鼓室图相比)呈正相关(r = 0.254, p < 0.05)。伴有A型鼓室图的听力损失(单侧0.8%,双侧0.3%)可能提示感音神经性听力损失。结论:本研究强调了对所有儿童进行普遍学前听力学筛查的重要性,特别是对面临医疗保健地理障碍的儿童。在社会团结协会的推动下,以社区为基础的干预措施可在减轻人群之间获得医疗保健的差距方面发挥关键作用。
{"title":"Preschool Hearing Screening: Nineteen Years of the Coração Delta Project in Campo Maior, Portugal.","authors":"Cláudia Reis, Luísa Monteiro, Conceição Monteiro, Joana Pereira, Joana Teixeira, João Mendes, Mariana Pereira, Magda Barrocas, Dionísia Gomes, Margarida Serrano","doi":"10.3390/audiolres15040104","DOIUrl":"10.3390/audiolres15040104","url":null,"abstract":"<p><p><b>Background/Objectives</b>: Preschool hearing screening is justified by the risk of late onset hearing loss, the high prevalence of otitis media with effusion in school-aged children, and the critical timing just before children begin formal reading and learn to write. This study describes the results of the annual preschool hearing screening program in Campo Maior from 2007 to 2025 (nineteen years) and correlates the audiological referral to the otoscopy findings by the otolaryngologists. <b>Methodology</b>: Retrospective study using clinical records from nineteen years of preschool hearing screening. <b>Results</b>: Screening identified 310 children (29% of 1068 screened) requiring referral to an ENT specialist. Of the 217 referred children evaluated by ENT, 198 (91.2%) had confirmed pathology or healthcare needs of medical intervention. A statistically significant positive association (r = 0.254, <i>p</i> < 0.05) existed between abnormal otoscopy findings and Type B or C2 tympanograms (versus Type A or C1). Hearing loss occurring with Type A tympanograms (0.8% unilaterally, 0.3% bilaterally) may suggest sensorineural hearing loss. <b>Conclusion</b>: This study reinforces the importance of universal preschool audiological screening for all children, particularly for children facing geographic barriers to healthcare. Community-based interventions facilitated by social solidarity associations can play a crucial role in mitigating healthcare access disparities across populations.</p>","PeriodicalId":44133,"journal":{"name":"Audiology Research","volume":"15 4","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12383093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-09DOI: 10.3390/audiolres15040102
David Ulrich Seidel, Simon Bode, Karel Kostev
Background: Numerous studies have demonstrated the beneficial effects of sodium-glucose cotransporter-2 (SGLT2) inhibitors on cardiovascular and renal outcomes in patients with heart failure and chronic kidney disease. However, whether SGLT2 inhibitors are also associated with a reduced risk of tinnitus has not been investigated.
Objective: This study aimed to investigate the association between SGLT2 inhibitor therapy and the incidence of tinnitus in patients with type 2 diabetes.
Methods: This retrospective cohort study was based on data from a nationally representative database of primary care practices in Germany from 2012 to 2023. Patients with type 2 diabetes who were treated with metformin and additionally received either an SGLT2 inhibitor or a dipeptidyl peptidase-4 (DPP4) inhibitor were included. Patients with a previous diagnosis of tinnitus were excluded. The primary outcome was the first tinnitus diagnosis documented by a primary care physician. The SGLT2 and DPP4 cohorts were compared for tinnitus incidence using Kaplan-Meier analysis and multivariable Cox regression.
Results: 66,750 patients with SGLT2 inhibitors and 82,830 with DPP4 inhibitors were analyzed. The cumulative 5-year incidence of tinnitus was 1.9% in both groups. The multivariable regression analysis did not show a significant association between SGLT2 therapy and the occurrence of a tinnitus diagnosis (HR: 1.04; 95% CI: 0.89-1.21).
Conclusion: There was no difference in tinnitus incidence between patients with SGLT2 or DPP4 inhibitors. The causes could lie in the heterogeneous, not purely vascular, etiology of tinnitus in general practitioners' practices. Future studies should include further clinical data, including confirmed hearing impairments.
{"title":"Association Between SGLT2 Inhibitor Therapy and the Incidence of Tinnitus in Patients with Type 2 Diabetes: A Retrospective Cohort Study.","authors":"David Ulrich Seidel, Simon Bode, Karel Kostev","doi":"10.3390/audiolres15040102","DOIUrl":"10.3390/audiolres15040102","url":null,"abstract":"<p><strong>Background: </strong>Numerous studies have demonstrated the beneficial effects of sodium-glucose cotransporter-2 (SGLT2) inhibitors on cardiovascular and renal outcomes in patients with heart failure and chronic kidney disease. However, whether SGLT2 inhibitors are also associated with a reduced risk of tinnitus has not been investigated.</p><p><strong>Objective: </strong>This study aimed to investigate the association between SGLT2 inhibitor therapy and the incidence of tinnitus in patients with type 2 diabetes.</p><p><strong>Methods: </strong>This retrospective cohort study was based on data from a nationally representative database of primary care practices in Germany from 2012 to 2023. Patients with type 2 diabetes who were treated with metformin and additionally received either an SGLT2 inhibitor or a dipeptidyl peptidase-4 (DPP4) inhibitor were included. Patients with a previous diagnosis of tinnitus were excluded. The primary outcome was the first tinnitus diagnosis documented by a primary care physician. The SGLT2 and DPP4 cohorts were compared for tinnitus incidence using Kaplan-Meier analysis and multivariable Cox regression.</p><p><strong>Results: </strong>66,750 patients with SGLT2 inhibitors and 82,830 with DPP4 inhibitors were analyzed. The cumulative 5-year incidence of tinnitus was 1.9% in both groups. The multivariable regression analysis did not show a significant association between SGLT2 therapy and the occurrence of a tinnitus diagnosis (HR: 1.04; 95% CI: 0.89-1.21).</p><p><strong>Conclusion: </strong>There was no difference in tinnitus incidence between patients with SGLT2 or DPP4 inhibitors. The causes could lie in the heterogeneous, not purely vascular, etiology of tinnitus in general practitioners' practices. Future studies should include further clinical data, including confirmed hearing impairments.</p>","PeriodicalId":44133,"journal":{"name":"Audiology Research","volume":"15 4","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12382665/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-07DOI: 10.3390/audiolres15040101
Ana Luísa Moura Rodrigues, Hashir Aazh
Background: The aim of this study was to conduct a systematic review of the research literature on the prevalence of psychiatric comorbidities in patients with hyperacusis and misophonia. Method: Four databases were searched: PubMed, PsycINFO, Scopus, and Web of Science (Wis)-last search conducted on the 16th of April 2024 to identify relevant studies. The methodological quality of each study was independently assessed using the JBI Critical Appraisal Checklist. Results: Five studies were included for the prevalence of psychiatric comorbidities in hyperacusis, and seventeen studies for misophonia. Among patients with hyperacusis, between 8% and 80% had depression, and between 39% and 61% had any anxiety disorder as measured via a diagnostic interview and/or self-report questionnaires. For misophonia, nine studies provided data on various forms of mood and anxiety disorders, with prevalences ranging from 1.1% to 37.3% and 0.2% to 69%, respectively. Conclusions: Although the 22 included studies varied considerably in design and scope, some recurring patterns of comorbidity were noted. However, apparent trends-such as the higher prevalence of mood and anxiety disorders compared to other psychiatric conditions-should be interpreted with caution, as most studies did not comprehensively assess a full range of psychiatric disorders. This likely skews prevalence estimates toward the conditions that were specifically investigated.
背景:本研究的目的是对有关听觉亢进和恐音症患者精神疾病共病患病率的研究文献进行系统回顾。方法:检索PubMed、PsycINFO、Scopus、Web of Science (Wis) 4个数据库,最后一次检索时间为2024年4月16日,确定相关研究。每个研究的方法学质量使用JBI关键评估清单进行独立评估。结果:5项研究纳入了听觉亢进的精神合并症患病率,17项研究纳入了恐音症。通过诊断性访谈和/或自我报告问卷调查,在听觉亢进患者中,8%至80%患有抑郁症,39%至61%患有焦虑症。对于恐音症,九项研究提供了各种形式的情绪和焦虑障碍的数据,患病率分别从1.1%到37.3%和0.2%到69%不等。结论:虽然22项纳入的研究在设计和范围上有很大的不同,但我们注意到一些反复出现的合并症模式。然而,明显的趋势——比如与其他精神疾病相比,情绪和焦虑障碍的患病率更高——应该谨慎解释,因为大多数研究并没有全面评估精神疾病的全部范围。这可能会使患病率估计偏向于具体调查的情况。
{"title":"Psychiatric Comorbidities in Hyperacusis and Misophonia: A Systematic Review.","authors":"Ana Luísa Moura Rodrigues, Hashir Aazh","doi":"10.3390/audiolres15040101","DOIUrl":"10.3390/audiolres15040101","url":null,"abstract":"<p><p><b>Background</b>: The aim of this study was to conduct a systematic review of the research literature on the prevalence of psychiatric comorbidities in patients with hyperacusis and misophonia. <b>Method</b>: Four databases were searched: PubMed, PsycINFO, Scopus, and Web of Science (Wis)-last search conducted on the 16th of April 2024 to identify relevant studies. The methodological quality of each study was independently assessed using the JBI Critical Appraisal Checklist. <b>Results</b>: Five studies were included for the prevalence of psychiatric comorbidities in hyperacusis, and seventeen studies for misophonia. Among patients with hyperacusis, between 8% and 80% had depression, and between 39% and 61% had any anxiety disorder as measured via a diagnostic interview and/or self-report questionnaires. For misophonia, nine studies provided data on various forms of mood and anxiety disorders, with prevalences ranging from 1.1% to 37.3% and 0.2% to 69%, respectively. <b>Conclusions</b>: Although the 22 included studies varied considerably in design and scope, some recurring patterns of comorbidity were noted. However, apparent trends-such as the higher prevalence of mood and anxiety disorders compared to other psychiatric conditions-should be interpreted with caution, as most studies did not comprehensively assess a full range of psychiatric disorders. This likely skews prevalence estimates toward the conditions that were specifically investigated.</p>","PeriodicalId":44133,"journal":{"name":"Audiology Research","volume":"15 4","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12383035/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-06DOI: 10.3390/audiolres15040097
Maria-Pia Tuset, Mary Daval, Daniel Levy, Denis Ayache, Stéphane Gargula
Objective: Hearing rehabilitation using hearing aids keeps increasing in the general population. Patient-related outcome measures are essential to evaluate benefits. Although the IOI-HA is routinely used in France, its translated version from 2002 has never been validated. This study aimed to assess the psychometric properties of the French version of the IOI-HA questionnaire. Design: Controlled, prospective, monocentric study performed between February 2024 and January 2025. The forward-backward technique was used for translation of the questionnaire. Study Sample: 100 patients fitted with hearing aids completed the questionnaire. Thirty-five patients were retested 15 days after first completion. Results: Internal consistency, assessed by Cronbach's alpha, was 0.863. Mean IOI-HA item scores ranged from 3.3 to 4.57. All seven items had a high degree of consistency with the total score, except for item Q1 which had a moderate score (0.45). Cronbach's alpha after item deletion confirmed internal consistency. Intra-class correlation coefficients ranged from 0.622 (Q7) to 0.767 (Q5) and were all statistically significant (p < 0.001), revealing high reliability over time. No significant correlation was found between item scores and age, unilateral or bilateral hearing aid use or accompanying symptoms (tinnitus, dizziness). Conclusions: The French translation of the IOI-HA questionnaire, published in 2002, is a valid and reliable questionnaire evaluating hearing aid satisfaction. This validated questionnaire can now be used in daily clinical practice.
{"title":"French Adaptation and Validation of the International Outcome Inventory on Hearing Aids (IOI-HA) Questionnaire.","authors":"Maria-Pia Tuset, Mary Daval, Daniel Levy, Denis Ayache, Stéphane Gargula","doi":"10.3390/audiolres15040097","DOIUrl":"10.3390/audiolres15040097","url":null,"abstract":"<p><p><b>Objective:</b> Hearing rehabilitation using hearing aids keeps increasing in the general population. Patient-related outcome measures are essential to evaluate benefits. Although the IOI-HA is routinely used in France, its translated version from 2002 has never been validated. This study aimed to assess the psychometric properties of the French version of the IOI-HA questionnaire. <b>Design:</b> Controlled, prospective, monocentric study performed between February 2024 and January 2025. The forward-backward technique was used for translation of the questionnaire. <b>Study Sample:</b> 100 patients fitted with hearing aids completed the questionnaire. Thirty-five patients were retested 15 days after first completion. <b>Results:</b> Internal consistency, assessed by Cronbach's alpha, was 0.863. Mean IOI-HA item scores ranged from 3.3 to 4.57. All seven items had a high degree of consistency with the total score, except for item Q1 which had a moderate score (0.45). Cronbach's alpha after item deletion confirmed internal consistency. Intra-class correlation coefficients ranged from 0.622 (Q7) to 0.767 (Q5) and were all statistically significant (<i>p</i> < 0.001), revealing high reliability over time. No significant correlation was found between item scores and age, unilateral or bilateral hearing aid use or accompanying symptoms (tinnitus, dizziness). <b>Conclusions:</b> The French translation of the IOI-HA questionnaire, published in 2002, is a valid and reliable questionnaire evaluating hearing aid satisfaction. This validated questionnaire can now be used in daily clinical practice.</p>","PeriodicalId":44133,"journal":{"name":"Audiology Research","volume":"15 4","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12382775/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-06DOI: 10.3390/audiolres15040100
Daniele Portelli, Sabrina Loteta, Mariangela D'Angelo, Cosimo Galletti, Leonard Freni, Rocco Bruno, Francesco Ciodaro, Angela Alibrandi, Giuseppe Alberti
Background/Objectives: Artificial Intelligence (AI) is increasingly being applied in otolaryngology, including cochlear implants (CIs). This study evaluates the accuracy and completeness of ChatGPT-4 and Microsoft Copilot in determining the appropriate implantation side based on audiological and radiological data, as well as the presence of tinnitus. Methods: Data from 22 CI patients (11 males, 11 females; 12 right-sided, 10 left-sided implants) were used to query both AI models. Each patient's audiometric thresholds, hearing aid benefit, tinnitus presence, and radiological findings were provided. The AI-generated responses were compared to the clinician-chosen sides. Accuracy and completeness were scored by two independent reviewers. Results: ChatGPT had a 50% concordance rate for right-side implantation and a 70% concordance rate for left-side implantation, while Microsoft Copilot achieved 75% and 90%, respectively. Chi-square tests showed significant associations between AI-suggested and clinician-chosen sides for both AI (p < 0.05). ChatGPT outperformed Microsoft Copilot in identifying radiological alterations (60% vs. 40%) and tinnitus presence (77.8% vs. 66.7%). Cronbach's alpha was >0.70 only for ChatGPT accuracy, indicating better agreement between reviewers. Conclusions: Both AI models showed significant alignment with clinician decisions. Microsoft Copilot was more accurate in implantation side selection, while ChatGPT better recognized radiological alterations and tinnitus. These results highlight AI's potential as a clinical decision support tool in CI candidacy, although further research is needed to refine its application in complex cases.
{"title":"ChatGPT and Microsoft Copilot for Cochlear Implant Side Selection: A Preliminary Study.","authors":"Daniele Portelli, Sabrina Loteta, Mariangela D'Angelo, Cosimo Galletti, Leonard Freni, Rocco Bruno, Francesco Ciodaro, Angela Alibrandi, Giuseppe Alberti","doi":"10.3390/audiolres15040100","DOIUrl":"10.3390/audiolres15040100","url":null,"abstract":"<p><p><b>Background/Objectives</b>: Artificial Intelligence (AI) is increasingly being applied in otolaryngology, including cochlear implants (CIs). This study evaluates the accuracy and completeness of ChatGPT-4 and Microsoft Copilot in determining the appropriate implantation side based on audiological and radiological data, as well as the presence of tinnitus. <b>Methods</b>: Data from 22 CI patients (11 males, 11 females; 12 right-sided, 10 left-sided implants) were used to query both AI models. Each patient's audiometric thresholds, hearing aid benefit, tinnitus presence, and radiological findings were provided. The AI-generated responses were compared to the clinician-chosen sides. Accuracy and completeness were scored by two independent reviewers. <b>Results</b>: ChatGPT had a 50% concordance rate for right-side implantation and a 70% concordance rate for left-side implantation, while Microsoft Copilot achieved 75% and 90%, respectively. Chi-square tests showed significant associations between AI-suggested and clinician-chosen sides for both AI (<i>p</i> < 0.05). ChatGPT outperformed Microsoft Copilot in identifying radiological alterations (60% vs. 40%) and tinnitus presence (77.8% vs. 66.7%). Cronbach's alpha was >0.70 only for ChatGPT accuracy, indicating better agreement between reviewers. <b>Conclusions</b>: Both AI models showed significant alignment with clinician decisions. Microsoft Copilot was more accurate in implantation side selection, while ChatGPT better recognized radiological alterations and tinnitus. These results highlight AI's potential as a clinical decision support tool in CI candidacy, although further research is needed to refine its application in complex cases.</p>","PeriodicalId":44133,"journal":{"name":"Audiology Research","volume":"15 4","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12383040/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}