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[Developing a psychiatrist's flair: Lessons learned from two clinical cases of olfactory reference syndrome]. [发展精神科医生的天赋:从两个嗅觉参照综合征的临床病例中吸取的教训]。
IF 0.4 Q4 PSYCHIATRY Pub Date : 2024-01-01
Morganne Masse, Emmanuel Stip

Olfaction is often neglected in psychiatric semiology, despite its clinical relevance and impact on social functioning. The olfactory reference syndrome (ORS), characterized by a false belief that a person emits a foul odor, causes severe distress and disrupts social functioning. This article aims to highlight the importance of olfaction in psychiatric semiology, with a focus on ORS. We present a study of two men with ORS, followed in a psychotic disorder unit, using the CARE criteria. A literature review conducted according to PRISMA guidelines examines 53 studies from PubMed, PsychInfo, Google Scholar, and Cairns. By complementing the clinical presentations, our analysis facilitates a discussion of current knowledge on ORS, refuting, nuancing and validating existing hypotheses regarding its nosography and etiology. We suggest to further explore our understanding of olfaction through its association with emotions, the formation of impressions, and the Theory of Mind. Better grasping how olfaction influences psychological and social functioning could improve diagnostic and therapeutic approaches to ORS in psychiatry.

嗅觉在精神病学符号学中经常被忽视,尽管它具有临床相关性和对社会功能的影响。嗅觉参照综合症(ORS)的特点是错误地认为一个人散发出难闻的气味,这会导致严重的痛苦,扰乱社会功能。本文旨在强调嗅觉在精神病学符号学中的重要性,重点是ORS。我们提出了一项研究,两名男性ORS,随后在精神障碍单位,使用护理标准。根据PRISMA指南进行的文献综述检查了来自PubMed、PsychInfo、b谷歌Scholar和Cairns的53项研究。通过补充临床表现,我们的分析促进了对ORS当前知识的讨论,驳斥,细化和验证有关其医院和病因的现有假设。我们建议通过嗅觉与情绪的联系、印象的形成和心理理论来进一步探索我们对嗅觉的理解。更好地掌握嗅觉如何影响心理和社会功能可以改善精神病学中ORS的诊断和治疗方法。
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引用次数: 0
150 ans de psychiatrie : histoire et évolution à l’Institut universitaire en santé mentale de Montréal. 精神病学 150 年:蒙特利尔大学精神健康研究所的历史与演变。
IF 0.4 Q4 PSYCHIATRY Pub Date : 2024-01-01
Emmanuel Stip, Lionel Cailhol, François Borgeat
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引用次数: 0
[New Educational Tool for 3D Simulation of Auditory Hallucinations, Co-Created with Voice Hearers: Pilot Study with Psychiatry Residents]. [与幻听者共同创作的听觉幻觉三维模拟新教育工具:精神病学住院医师试点研究]。
IF 0.4 Q4 PSYCHIATRY Pub Date : 2024-01-01
Kevin Zemmour, Laurie Pelletier, Sandrine Rousseau, Serge Tracy, Catherine Lejeune, Alain Berry, Sofian Audry, Kevin Whittingstall, Sylvain Grignon, Philippe-Aubert Gauthier

Objective Therapeutic relationship is a cornerstone in the treatment of schizophrenia. However, certain personal factors on the part of psychiatrists can hinder it, notably the lack of experience with auditory hallucinations. Such factors can lead to a decrease in empathy and, consequently, a negative alteration in the therapeutic relationship. Previous studies have shown that auditory hallucination simulators have a positive impact on mental health professionals. Yet, to our knowledge, no such test has been conducted on the psychiatry resident population. To address this gap, a research team was formed, including voice hearers, psychiatrists, acoustical engineering researchers, qualitative research experts, and actor-authors. This team collaboratively created the first three-dimensional voice simulator (3DV simulator) using binaural sound reproduction technology. The objective of this pilot study is to evaluate the reaction of psychiatry residents to this 3DV simulator. Methods In this exploratory and descriptive study, psychiatry residents (n=12) were included and invited to listen to the 3DV simulator for 15 minutes. Empathy was assessed before and after the 3DV simulation using the Jefferson Scale of Physician Empathy (JSPE©), a scale to evaluate empathy in healthcare professionals. Following the simulation, participants were invited to participate in a brief semi-structured interview consisting of an open-ended and general question about their experiences, along with additional questions. Results Participants (83.3%) found the 3DV simulator interesting and useful. They perceived the simulation as an aid to better understand the patients' experience and to better identify with their lived realities. Our study did not find a statistically significant difference in the total JSPE© score before and after the simulation (p = 0.797). Conclusion This article addresses the need to enhance the empathy of psychiatry residents towards individuals suffering from auditory hallucinations. One uniqueness of this pilot project is how the simulator was designed collaboratively by a multidisciplinary and inclusive team involving voice hearers throughout the research process. The results of this pilot study presented in this article underscore the necessity of continually improving educational interventions to support the development of empathy among psychiatry residents. They also suggest that the 3DV simulator was well-received by the residents, encouraging the conduct of larger-scale studies.

目标 治疗关系是治疗精神分裂症的基石。然而,精神科医生的某些个人因素会阻碍治疗关系的建立,尤其是缺乏处理幻听的经验。这些因素会导致共情能力下降,从而对治疗关系产生负面影响。以往的研究表明,幻听模拟器对心理健康专业人员有积极的影响。然而,据我们所知,还没有针对精神病学住院医师群体进行过此类测试。为了填补这一空白,我们成立了一个研究小组,成员包括幻听者、精神科医生、声学工程研究人员、定性研究专家和演员作者。该团队利用双耳声音再现技术,合作创建了首个三维声音模拟器(3DV 模拟器)。本试验研究的目的是评估精神病学住院医师对该 3DV 模拟器的反应。方法 在这项探索性和描述性研究中,精神病学住院医师(12 人)被邀请聆听 3DV 模拟器 15 分钟。使用杰斐逊医生移情量表(JSPE©)对3DV 模拟前后的移情进行评估,该量表用于评估医护人员的移情。模拟后,参与者应邀参加了一个简短的半结构化访谈,访谈内容包括一个有关其经历的开放式一般性问题以及其他问题。结果 参与者(83.3%)认为 3DV 模拟器既有趣又有用。他们认为模拟器有助于更好地了解病人的经历,更好地认同他们的生活现实。我们的研究没有发现模拟前后的 JSPE© 总分有显著的统计学差异(p = 0.797)。结论 本文论述了提高精神科住院医师对幻听患者的同理心的必要性。该试点项目的独特之处在于,模拟器是由一个多学科和包容性团队共同设计的,整个研究过程都有幻听者的参与。本文介绍的试点研究结果强调,有必要不断改进教育干预措施,以支持精神科住院医生共情能力的发展。这些结果还表明,3DV 模拟器深受住院医师的欢迎,因此鼓励开展更大规模的研究。
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引用次数: 0
[Perspectives on the Access and Effectiveness of Psychosocial Services Offered in the Context of Breast Cancer: A Qualitative Study of Patient's Experience Before and During the COVID-19 Pandemic]. [关于乳腺癌社会心理服务的获取和有效性的观点:COVID-19大流行之前和期间患者体验的定性研究]。
IF 0.4 Q4 PSYCHIATRY Pub Date : 2024-01-01
Justine Fortin, Clarisse Defer, Alain Brunet, Marjorie Montreuil, Marie-France Marin

Background The experience of breast cancer diagnosis leads to being confronted with the unknown and uncertainty. In some cases, patients develop symptoms of psychological distress after the diagnosis, which can have a negative influence during and after treatment. In Quebec, there are several breast cancer clinics that appear to offer psychological assessment to patients and psychosocial services during the different phases of the disease. To our knowledge, few Quebec studies have looked at the effectiveness of and access to psychosocial services in times of non-crisis. The COVID-19 pandemic also led to changes in breast clinics (e.g., closure of screening clinics, reception of diagnosis remotely, changes in treatment plans). However, no Canadian study has qualitatively examined patients' experiences of the impact of the pandemic on access and effectiveness of these services. Objectives The first objective of this qualitative study is to describe the perspectives of Quebec women who received a breast cancer diagnosis and/or treatment during the pandemic on the access to and effectiveness of psychosocial services. In addition, the second objective is to identify patient recommendations for improving the well-being of patients receiving psychosocial oncology services. Method As part of this larger project, we conducted semi-structured interviews with 18 Quebec patients (M = 47.05 years, SD = 9.07) diagnosed and/or treated for breast cancer before and during the pandemic. Descriptive analyses performed in MaxQDA allowed us to establish a thematic guide and narrative summaries. Results A minority of participants (n = 6) were offered psychosocial services at the time of their diagnosis. Although not all of them used the resources offered, they appreciated having them available. In contrast, 12 participants did not receive psychosocial resources, and more than half of these women were unsatisfied as they experienced intense psychological distress following diagnosis, which continued during treatment. Many women (n = 12) had to seek help on their own. Conclusion In order to improve the long-term experience of patients in times of crisis and non-crisis in Quebec, the results show that it could be beneficial to offer psychosocial services based on the needs of users, rather than solely on the severity of psychological symptoms.

背景 乳腺癌确诊后,患者会面临未知和不确定性。在某些情况下,患者在确诊后会出现心理困扰症状,这可能会在治疗期间和治疗后产生负面影响。在魁北克,有几家乳腺癌诊所似乎在疾病的不同阶段为患者提供心理评估和社会心理服务。据我们所知,魁北克很少有研究关注非危机时期心理服务的有效性和获取途径。COVID-19 大流行也导致了乳腺诊所的改变(如关闭筛查诊所、远程接受诊断、改变治疗计划)。然而,加拿大还没有任何一项研究对患者在大流行对这些服务的获取和有效性的影响方面的体验进行定性研究。目标 本定性研究的第一个目标是描述在大流行期间接受乳腺癌诊断和/或治疗的魁北克妇女对获得社会心理服务及其有效性的看法。此外,第二个目标是确定患者建议,以改善接受社会心理肿瘤服务的患者的福祉。方法 作为该大型项目的一部分,我们对 18 名魁北克患者(M = 47.05 岁,SD = 9.07)进行了半结构化访谈,这些患者在大流行之前和期间被诊断为乳腺癌并/或接受了治疗。通过 MaxQDA 进行描述性分析,我们建立了主题指南和叙述性摘要。结果 少数参与者(n = 6)在确诊时获得了社会心理服务。虽然并非所有参与者都使用了所提供的资源,但他们对能够获得这些资源表示感谢。相比之下,有 12 名参与者没有获得社会心理资源,其中半数以上的女性对社会心理资源不满意,因为她们在确诊后经历了严重的心理困扰,而且这种困扰在治疗期间仍在持续。许多妇女(12 人)不得不自行寻求帮助。结论 为了改善魁北克患者在危机和非危机时期的长期体验,研究结果表明,根据使用者的需求而非仅仅根据心理症状的严重程度来提供社会心理服务是有益的。
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引用次数: 0
[Professionals' Perceptions Regarding the Implementation of Guided Self-help in the context of the Programme québécois pour les troubles mentaux]. [专业人员对在魁北克心理问题计划框架内实施指导性自助的看法]。
IF 0.4 Q4 PSYCHIATRY Pub Date : 2024-01-01
Quentin Bet, Alexane Gilbert, Juliette Bergeron, Isabelle Fournel, Josée Savard, Guillaume Foldes-Busque, Martin D Provencher

Objective Common mental disorders, such as anxiety and depression, have many individual and societal consequences. Various treatments are available for people with these diagnoses, including medication and cognitive behavioral therapy. When these disorders are mild or moderate, psychotherapy is the recommended first-line treatment, given its greater long-term efficacy than pharmacotherapy. However, this is not what is observed in practice: medication is much more widely used than psychotherapy, the latter's accessibility being greatly reduced by long waiting lists. An alternative to these accessibility difficulties is the stepped-care model, which includes guided self-help. These are low-intensity interventions that enable more people to be treated with fewer resources (e.g., fewer meetings with a professional). The Programme québécois pour les troubles mentaux (PQPTM; Quebec Program for Mental Disorders) is a stepped-care model recently implemented in some settings in Quebec. The aim of this study is to gather the perceptions of social workers (SWs) in a Centre intégré (universitaire) de santé et de services sociaux (CI[U]SSS; Community mental health center) on the implementation of the PQPTM guided self-help. Methods To this end, three focus groups of approximately 1h30 were conducted with 13 SWs. The data were coded and analyzed using a thematic qualitative inductive-deductive approach, based on the Consolidated Framework for Implementing Research (CFIR) and the participants' responses obtained during the focus groups. Results The barriers and facilitators to PQPTM guided self-help implementation identified relate to different CFIR constructs: intervention characteristics (e.g., monitoring, type of self-help), internal implementation parameters (e.g., training, organizational pressures), caregiver characteristics (e.g., experience, appropriation time), user characteristics (e.g., age, personality) and process (e.g., treatment integrity, supervision). The results of this qualitative study show that SWs have varied perceptions and opinions of the PQPTM guided self-help: 64% of the themes discussed were nuanced, while 25% were considered exclusively as barriers and 11% exclusively as facilitators. Conclusion These results shed light on the factors that can contribute to the successful implementation of the PQPTM guided self-help in Quebec, with a view to improving it at the heart of the specific CI(U)SSS of the current study and in other mental health centers in Quebec. Several recommendations are made in this respect: for example, to increase upstream planning for future implementations, to maintain access to training and supervision, and to guarantee the availability and printing of self-help guides.

目标 焦虑症和抑郁症等常见精神障碍会给个人和社会带来许多后果。针对这些疾病的治疗方法多种多样,包括药物治疗和认知行为疗法。当这些障碍属于轻度或中度时,心理治疗是推荐的一线治疗方法,因为心理治疗的长期疗效优于药物治疗。然而,实际情况并非如此:药物治疗比心理治疗使用得更广泛,而心理治疗的可及性却因漫长的等待名单而大打折扣。阶梯式护理模式是解决这些困难的另一种方法,其中包括指导自助。这些都是低强度的干预措施,使更多的人能够以较少的资源(如与专业人员会面的次数较少)获得治疗。魁北克精神障碍项目(PQPTM)是最近在魁北克的一些环境中实施的一种阶梯式护理模式。本研究的目的是收集一家综合社会福利中心(CI[U]SSS;社区精神健康中心)的社工(SWs)对实施 PQPTM 指导自助的看法。为此,我们与 13 名社工进行了三次焦点小组讨论,时间约为 1 小时 30 分钟。根据研究实施综合框架(CFIR)和参与者在焦点小组中的回答,采用主题定性归纳-演绎法对数据进行了编码和分析。结果 在 PQPTM 指导下实施自助的障碍和促进因素与不同的 CFIR 构建相关:干预特征(如监控、自助类型)、内部实施参数(如培训、组织压力)、护理者特征(如经验、适当时间)、使用者特征(如年龄、个性)和过程(如治疗完整性、监督)。这项定性研究的结果表明,社工对 PQPTM 引导式自助有不同的认识和看法:在讨论的主题中,64%有细微差别,25%完全被视为障碍,11%完全被视为促进因素。结论 这些结果揭示了有助于在魁北克省成功实施 PQPTM 引导式自助的因素,以期在当前研究的特定 CI(U)SSS 中心和魁北克省其他精神健康中心加以改进。在这方面提出了几项建议:例如,增加未来实施的上游规划,保持培训和监督的机会,以及保证自助指南的可用性和印刷。
{"title":"[Professionals' Perceptions Regarding the Implementation of Guided Self-help in the context of the Programme québécois pour les troubles mentaux].","authors":"Quentin Bet, Alexane Gilbert, Juliette Bergeron, Isabelle Fournel, Josée Savard, Guillaume Foldes-Busque, Martin D Provencher","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Objective Common mental disorders, such as anxiety and depression, have many individual and societal consequences. Various treatments are available for people with these diagnoses, including medication and cognitive behavioral therapy. When these disorders are mild or moderate, psychotherapy is the recommended first-line treatment, given its greater long-term efficacy than pharmacotherapy. However, this is not what is observed in practice: medication is much more widely used than psychotherapy, the latter's accessibility being greatly reduced by long waiting lists. An alternative to these accessibility difficulties is the stepped-care model, which includes guided self-help. These are low-intensity interventions that enable more people to be treated with fewer resources (e.g., fewer meetings with a professional). The Programme québécois pour les troubles mentaux (PQPTM; Quebec Program for Mental Disorders) is a stepped-care model recently implemented in some settings in Quebec. The aim of this study is to gather the perceptions of social workers (SWs) in a Centre intégré (universitaire) de santé et de services sociaux (CI[U]SSS; Community mental health center) on the implementation of the PQPTM guided self-help. Methods To this end, three focus groups of approximately 1h30 were conducted with 13 SWs. The data were coded and analyzed using a thematic qualitative inductive-deductive approach, based on the Consolidated Framework for Implementing Research (CFIR) and the participants' responses obtained during the focus groups. Results The barriers and facilitators to PQPTM guided self-help implementation identified relate to different CFIR constructs: intervention characteristics (e.g., monitoring, type of self-help), internal implementation parameters (e.g., training, organizational pressures), caregiver characteristics (e.g., experience, appropriation time), user characteristics (e.g., age, personality) and process (e.g., treatment integrity, supervision). The results of this qualitative study show that SWs have varied perceptions and opinions of the PQPTM guided self-help: 64% of the themes discussed were nuanced, while 25% were considered exclusively as barriers and 11% exclusively as facilitators. Conclusion These results shed light on the factors that can contribute to the successful implementation of the PQPTM guided self-help in Quebec, with a view to improving it at the heart of the specific CI(U)SSS of the current study and in other mental health centers in Quebec. Several recommendations are made in this respect: for example, to increase upstream planning for future implementations, to maintain access to training and supervision, and to guarantee the availability and printing of self-help guides.</p>","PeriodicalId":44148,"journal":{"name":"Sante Mentale au Quebec","volume":"49 1","pages":"99-122"},"PeriodicalIF":0.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142113222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[AI based Evaluation of Psychotrauma related to Lahars in the Commune of Prêcheur in the French Antilles]. [基于人工智能的法属安的列斯群岛 Prêcheur 公社拉哈尔火山精神创伤评估]。
IF 0.4 Q4 PSYCHIATRY Pub Date : 2024-01-01
Louis Jehel, Mathieu Guidère

Objectives Natural disasters have a significant impact on mental health. Data collected from the population offer a unique opportunity for post-disaster monitoring to help identify psychological support needs. The aim of this study is: 1) to identify psychopathological aspects for the county of Prêcheur at risk from lahars (volcanic lava), and 2) to phenotype psychopathological aspects from data collected from the population. Method We applied an artificial intelligence (AI) assisted psycho-phenotyping method to data from 40 people over a 20-month period, to extract psychopathological and psychiatric aspects linked to traumatic natural hazards. These were then compared with the results of psychometric tests measuring overall mental health and post-traumatic stress. Results Rumination and negativation were among the most important psychopathological aspects identified. In addition, we noted the presence of re-experiencing and avoidance as core psychiatric dimensions over time. Among these, cognitive avoidance and emotional avoidance were found and seem to have emerged after the disaster. Conclusion We have proposed a new syndromic surveillance approach for mental health based on digital data that can support conventional approaches by providing additional useful information in the context of a disaster. Further studies are needed to better control bias, identify associations with valid instruments, and explore computational methods for continuous adjustment of the AI-analysis model.

目标 自然灾害对心理健康有重大影响。从居民中收集的数据为灾后监测提供了一个独特的机会,有助于确定心理支持需求。本研究的目的是:1)识别面临火山熔岩(泻湖)风险的普雷歇尔县的心理病理学方面;2)从收集到的人口数据中对心理病理学方面进行表型。方法 我们采用人工智能(AI)辅助心理表型方法,对 40 人 20 个月的数据进行分析,提取与创伤性自然灾害相关的精神病理学和精神病学方面的内容。然后将这些数据与测量整体心理健康和创伤后应激的心理测试结果进行比较。结果 我们发现,遐想和消极情绪是最重要的精神病理因素。此外,我们还注意到,随着时间的推移,重新体验和回避也是核心的精神病理学方面。其中,认知回避和情感回避似乎是在灾难发生后出现的。结论 我们提出了一种新的基于数字数据的心理健康综合征监测方法,它可以在灾难背景下提供额外的有用信息,从而为传统方法提供支持。我们还需要进一步研究,以更好地控制偏差,确定与有效工具的关联,并探索对人工智能分析模型进行持续调整的计算方法。
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引用次数: 0
Itinérance et santé mentale en région : mon expérience de psychiatre-dépanneur. 地区的无家可归与心理健康:我作为便利店精神科医生的经验。
IF 0.4 Q4 PSYCHIATRY Pub Date : 2024-01-01
Vincent Laliberté
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引用次数: 0
[Digital well-being, a technological mental health issue: The smartphone role]. [数字幸福感,一个技术性心理健康问题:智能手机的作用]。
IF 0.4 Q4 PSYCHIATRY Pub Date : 2024-01-01
Yasser Khazaal, Germano Vera Cruz

Objectives To introduce the concept of digital well-being and explore the place of digital tools in the service of this well-being. Methods The article is based on a description of the concept of digital well-being, the intervention models currently available and the possibilities for improvement of these models. Findings Over the past decade, smartphone use has become almost ubiquitous in modern society. The average person spends several hours a day on their device, especially among teenagers and young adults. With smart, interactive, convenient and always-on connectivity, individuals face new challenges and pressures related to when, where, how and how intensively they choose to connect or disconnect from the services provided by the smartphone. Problematic smartphone use has been linked to mental health disorders and functional problems. The concept of digital well-being has recently been introduced to address this challenge of using digital technologies to promote well-being. This is the subjective and individual experience of an optimal balance between the advantages and disadvantages associated with digital technology. Today's interventions are mostly based on technological tools focusing on screen-time control. The results of such interventions are mixed. Conclusion Better integration of dynamic human-machine interfaces may be essential for optimal efficiency of tools aiming to support digital wellbeing.

目的介绍数字幸福的概念,并探讨数字工具在服务于这种幸福中的地位。方法本文在描述数字幸福的概念、现有的干预模型和改进这些模型的可能性的基础上。在过去的十年里,智能手机的使用在现代社会几乎无处不在。人们平均每天花几个小时在电子设备上,尤其是青少年和年轻人。随着智能、互动、方便和永远在线的连接,个人面临着新的挑战和压力,这些挑战和压力与他们何时、何地、如何以及如何选择连接或断开智能手机提供的服务有关。有问题的智能手机使用与精神健康障碍和功能问题有关。数字幸福的概念最近被引入,以解决使用数字技术促进幸福的挑战。这是一种主观和个人的体验,在与数字技术相关的优点和缺点之间取得最佳平衡。今天的干预措施主要基于技术工具,重点是控制屏幕时间。这些干预措施的结果喜忧参半。结论:更好地集成动态人机界面可能是优化工具效率的必要条件,旨在支持数字健康。
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引用次数: 0
L’IUSMM et l’Université de Montréal : 150 ans de synergie au service de la santé mentale. IUSMM和Universite de Montreal: 150年的心理健康协同作用。
IF 0.4 Q4 PSYCHIATRY Pub Date : 2024-01-01
Patrick Cossette
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引用次数: 0
[The Signature Biobank: History and perspectives of a longitudinal project investigating the biological, psychological, and social signatures of patients visiting the emergency of the Institut universitaire en santé mentale de Montréal]. [签名生物样本库:一个纵向项目的历史和观点,该项目调查了到蒙特里萨大学精神健康研究所就诊的病人的生物、心理和社会特征]。
IF 0.4 Q4 PSYCHIATRY Pub Date : 2024-01-01
Enzo Cipriani, Philippe Kerr, Cécile Le Page, Charles-Édouard Giguère, Sonia Lupien, Stéphane Guay, Robert-Paul Juster
<p><p>Objectives In 2008, the National Institute of Mental Health (NIMH) published its strategic plan to structure future research aims and objectives including the development of a new method of classifying mental health disorders. This strategic plan gave rise to the Research Domain Criteria (RDoC) project, a framework aimed at establishing major functional domains of the human psyche ranging from normal to pathological. The Signature Consortium was created in 2009 to develop a data bank capable of contributing to the development of RDoC by identifying profiles, or Signatures, of a psychiatric population, collecting biological, psychosocial, and clinical indicators at critical moments in the care and follow-up of patients visiting the care structures of the Institut universitaire en santé mentale de Montréal (IUSMM). Here, we will briefly present the available data and outline some socio-demographic characteristics of our sample, in particular according to diagnosis. Methods By involving over 80 researchers, clinicians, staff, and the support of the IUSMM's institutional services (laboratory, IT, legal and ethics departments), this initiative has led to the creation of a unique data bank in Canada. Data for this biobank were collected during patients' visits to the IUSMM's psychiatric emergency department and during a follow-up in outpatient clinics. A control group was also created, with local recruitment of participants with no self-reported history of psychiatric hospitalization in the last 5 years, and with similar demographics to the psychiatric cohort. Psychological data (e.g., depressive, and psychotic symptoms scales) and socio-demographic data (e.g., marital status) were gathered from self-reported questionnaires. Medical and administrative data (e.g., treatment and diagnosis) were collected from treating psychiatrists and from the hospital's electronic registry (OACIS). Blood, hair, and saliva samples were also collected and analyzed to measure numerous biomarkers. Socio-demographic characteristics were compared based on primary diagnosis. Results Between 2012 and 2020, the Signature Biobank recruited 149 control participants and over 2172 psychiatric patients aged 17 to 81, of whom 2085 agreed to complete questionnaires, and 1986 donated biological samples. Thanks to these data, the Biobank has contributed to over forty research projects, 16 scientific publications in indexed international journals, permitted to validate 5 psychosocial questionnaires for psychiatric inpatients, and was used to create a composite sociocultural gender score. Globally, the participants presented a precarious socio-demographic profile. Patients diagnosed with a psychotic disorder seem to present the most disadvantaged profile regarding financial, professional, and relational dimensions. Conclusion The Signature Biobank is a unique biobank in North America studying mental health disorders by collecting bio-psycho-social data and associated biospecimens in
2008年,国家心理健康研究所(NIMH)公布了其战略计划,以构建未来的研究目标和目标,包括开发一种新的精神健康障碍分类方法。这一战略计划引发了研究领域标准(RDoC)项目,该框架旨在建立从正常到病理的人类心理主要功能领域。签名联盟成立于2009年,目的是建立一个数据库,通过确定精神病人群的概况或签名,在护理和跟踪访问蒙特精神病学大学研究所(IUSMM)护理机构的患者的关键时刻收集生物学、社会心理和临床指标,从而促进RDoC的发展。在这里,我们将简要介绍现有数据,并概述我们样本的一些社会人口学特征,特别是根据诊断。通过80多名研究人员、临床医生、工作人员的参与,以及IUSMM机构服务部门(实验室、IT、法律和道德部门)的支持,该倡议促成了加拿大独一无二的数据库的创建。该生物库的数据是在患者访问IUSMM的精神急诊科和门诊随访期间收集的。另外还建立了一个控制组,在当地招募的参与者在过去5年中没有自我报告的精神病学住院史,并且具有与精神病学队列相似的人口统计学特征。心理数据(如抑郁和精神病症状量表)和社会人口学数据(如婚姻状况)从自我报告的问卷中收集。医疗和行政数据(例如,治疗和诊断)是从治疗精神病医生和医院电子登记处收集的。血液、头发和唾液样本也被收集和分析,以测量许多生物标志物。根据初步诊断比较社会人口学特征。结果2012年至2020年,Signature Biobank招募了149名对照参与者和2172名年龄在17岁至81岁之间的精神病患者,其中2085人同意完成问卷调查,1986人捐赠了生物样本。多亏了这些数据,生物银行为40多个研究项目做出了贡献,在索引国际期刊上发表了16篇科学论文,允许对精神病住院患者进行5项心理社会问卷的验证,并用于创建综合社会文化性别评分。从全球来看,参与者呈现出不稳定的社会人口状况。被诊断为精神障碍的患者似乎在财务、职业和关系方面表现出最不利的形象。结论Signature Biobank是北美地区唯一一个通过收集精神科急诊生物-心理-社会数据和相关生物标本来研究精神健康障碍的生物库。虽然招募和数据收集已经完成,但生物银行仍在继续通过样本分析和参与独立研究项目来增加生物数据。
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