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The importance of considering the minimum interaural attenuation value in the masking procedure of pure-tone audiometry 在纯音测听掩蔽过程中考虑最小耳间衰减值的重要性
IF 0.1 Q4 OTORHINOLARYNGOLOGY Pub Date : 2022-04-01 DOI: 10.4103/indianjotol.indianjotol_12_21
M. Zakaria
In pure-tone audiometry (PTA) testing, air conduction (AC) and bone conduction (BC) thresholds are documented accordingly to obtain complete information on the hearing status. Nevertheless, due to the cross-hearing phenomenon, a masking procedure is typically implemented in PTA as an effort to obtain the exact (masked) AC and BC thresholds. As indicated by the respective masking rules, the decision to carry out the masking procedure is based on the “suggested” minimum interaural attenuation (IAA), which is 40 dB (for headphones), regardless of frequency. In this case report, the importance of considering the minimum IAA value based on research findings is highlighted. In particular, to produce more reliable PTA results, the masking procedure can be conducted by considering a lower IAA value (<40 dB).
在纯音测听(PTA)测试中,空气传导(AC)和骨传导(BC)阈值相应记录,以获得听力状态的完整信息。然而,由于交叉听音现象,在PTA中通常实施掩蔽程序,以获得准确的(掩蔽的)AC和BC阈值。正如各自的屏蔽规则所示,执行屏蔽程序的决定是基于“建议的”最小耳间衰减(IAA),即40 dB(耳机),无论频率如何。在本病例报告中,强调了基于研究结果考虑最小IAA值的重要性。特别是,为了产生更可靠的PTA结果,可以考虑较低的IAA值(<40 dB)来进行掩蔽程序。
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引用次数: 0
An update on autosomal recessive hearing loss and loci involved in it 常染色体隐性听力损失及其相关基因座的研究进展
IF 0.1 Q4 OTORHINOLARYNGOLOGY Pub Date : 2022-01-01 DOI: 10.4103/indianjotol.indianjotol_115_21
F. Azadegan-Dehkordi, Mahbobeh Koohiyan, M. Hoseini
Hearing plays an important role in human development and childhood speech learning for the proper functioning and development of people in society. Hearing loss (HL) is one of the most abnormal disabilities that affect the human senses. This disability may be due to genetic or environmental factors or both. Congenital HL is a disorder that occurs in at least 1 in 1000 births. At least 42 genetic loci are associated with syndromes, while more than 163 are associated with nonsyndromic HL (NSHL), and no specific gene therapy treatment has yet been proposed. Investigate the types of genes involved in regulating hair cell adhesion “and evaluate functions such as intracellular transport, the release of neurotransmitters, ion homeostasis, and hair cell cytoskeleton, and whether defects in them can impair cochlear and inner ear function.” Can help diagnose and treat the disease through various methods, including gene therapy. Given the complex internal and external structures of the ear, nervous system, and auditory mechanisms, it is not surprising that abnormalities in hundreds of different genes may lead to HL. In recent years, with the increasing number of studies on genes involved in congenital HL, counseling and treatment options with the help of gene therapy have increased. In this study, we aimed to describe genes and proteins and their functions in NSHL in the inner ear for screening and diagnostic programs of live birth and classify the genes involved in this model of deafness to open the door to gene therapy. It is on these genes. We hope to develop new molecular and gene therapies for autosomal recessive NSHL.
听力在人类发展和儿童言语学习中发挥着重要作用,有助于人们在社会中的正常运作和发展。听力损失(HL)是影响人类感官的最不正常的残疾之一。这种残疾可能是由于遗传或环境因素造成的,也可能是两者兼而有之。先天性HL是一种至少发生在千分之一新生儿中的疾病。至少有42个遗传基因座与综合征有关,而超过163个基因座与非综合征性HL(NSHL)有关,目前还没有提出具体的基因治疗方法。研究参与调节毛细胞粘附的基因类型,“评估细胞内运输、神经递质释放、离子稳态和毛细胞骨架等功能,以及其中的缺陷是否会损害耳蜗和内耳功能。”可以通过包括基因治疗在内的各种方法帮助诊断和治疗该疾病。考虑到耳朵、神经系统和听觉机制的复杂内部和外部结构,数百个不同基因的异常可能导致HL也就不足为奇了。近年来,随着对先天性HL相关基因的研究越来越多,借助基因治疗的咨询和治疗选择也越来越多。在这项研究中,我们旨在描述内耳NSHL中的基因和蛋白质及其功能,用于活产的筛查和诊断程序,并对这种耳聋模型中涉及的基因进行分类,为基因治疗打开大门。这取决于这些基因。我们希望为常染色体隐性遗传NSHL开发新的分子和基因治疗方法。
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引用次数: 0
Microbial flora of mastoid cavity after canal wall down (CWD) mastoidectomy 乳突切除术后乳突腔的微生物区系
IF 0.1 Q4 OTORHINOLARYNGOLOGY Pub Date : 2022-01-01 DOI: 10.4103/indianjotol.indianjotol_247_20
B. Barati, M. Ghazizadeh
Introduction: Many scientists have worked on microbial flora of the ear canal or middle ear in nonoperated patients, but it is not clear that what changes would be occurred in the flora of the mastoid cavity postoperatively. It can help the surgeons to choose the appropriate drugs in the perioperative period. The study was designed to investigate the microbial flora of the middle ear and mastoid cavities after canal wall down (CWD) mastoidectomy. Materials and Methods: The survey was designed as a prospective cross-sectional study. All patients with chronic otitis media who had undergone CWD mastoidectomy in a public university hospital from 2014 to 2017 were enrolled in the study. They were periodically followed up postoperatively at least for 6 months. Swab sampling from ear cavity was performed, and the samples were sent for culture and antibiogram. Each specimen was sent for bacterial and fungal analysis. If bacterial culture result was positive, the sensitivity of the cultured organisms to common antibiotics was also assessed. Results: Seventy-four patients entered into the survey. Twenty-six (35%) of samples were positive for bacteria, and 11 (14.5%) were positive for fungi. Furthermore, 3 (4%) of the studied ears were positive simultaneously for both bacterial and fungal culture. Among cultured bacteria, Staphylococcus epidermidis was the most common species (29%). Candida species was the most common fungal species (8%). Conclusions: Microbial infection is a common finding after CWD mastoidectomy. S. epidermidis and Candida species should be considered as the primary targets of treatment.
导言:许多科学家对非手术患者耳道或中耳的微生物菌群进行了研究,但尚不清楚术后乳突腔菌群会发生什么变化。它可以帮助外科医生在围手术期选择合适的药物。本研究旨在探讨中耳乳突切除术后乳突腔内微生物菌群的变化。材料与方法:本调查设计为前瞻性横断面研究。所有2014年至2017年在公立大学医院行CWD乳突切除术的慢性中耳炎患者均被纳入研究。术后定期随访至少6个月。耳腔拭子取样,送培养及抗生素检查。每个标本送去进行细菌和真菌分析。如果细菌培养结果为阳性,还评估培养的微生物对常用抗生素的敏感性。结果:74例患者纳入调查。细菌阳性26份(35%),真菌阳性11份(14.5%)。其中3只(4%)耳同时呈细菌和真菌培养阳性。在培养的细菌中,表皮葡萄球菌是最常见的菌种(29%)。念珠菌是最常见的真菌种类(8%)。结论:微生物感染是CWD乳突切除术后常见的发现。表皮葡萄球菌和念珠菌应被视为治疗的主要目标。
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引用次数: 0
Atypical manifestation in vestibular schwannoma 前庭神经鞘瘤的不典型表现
IF 0.1 Q4 OTORHINOLARYNGOLOGY Pub Date : 2022-01-01 DOI: 10.4103/indianjotol.indianjotol_99_21
A. Baki, Wan Draman, Z. Salahuddin, Nik Adilah Nik Othman
The cerebellopontine angle (CPA) is a cerebrospinal fluid-filled space, found at the junction between the cerebellum and pons. Vestibular schwannoma (VS) is the most common CPA tumor. Typical initial symptoms are unilateral or asymmetrical hearing impairment, tinnitus in the affected ear, or imbalance or vertigo. We report an unusual case of the patient who presented with right sensorineural hearing loss but was found to have left VS in the normal hearing ear.
桥小脑角(CPA)是一个充满脑脊液的空隙,位于小脑和桥脑交界处。前庭神经鞘瘤是最常见的CPA肿瘤。典型的初始症状是单侧或不对称听力损害,耳鸣,或不平衡或眩晕。我们报告一个不寻常的病例的病人谁提出了右感音神经性听力损失,但被发现有左VS在正常听力的耳朵。
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引用次数: 0
Temporal bone rhabdomyosarcoma mimicking chronic suppurative otitis media 模拟慢性化脓性中耳炎的颞骨横纹肌肉瘤
IF 0.1 Q4 OTORHINOLARYNGOLOGY Pub Date : 2022-01-01 DOI: 10.4103/indianjotol.indianjotol_151_21
Isha Shah, S. Malukar, Jayesh Singh, Ankita Parikh, U. Kunikullaya
Rhabdomyosarcoma (RMS) is one of the most commonly encountered soft-tissue sarcomas in childhood. The most common location is in the head-and-neck region, followed by the urogenital system, extremities, and torso. Head and neck is a common site though the temporal bone is an extremely rare site with only a few reported cases in the literature till now. Herein, we report a case of a sclerosing type of temporal bone RMS in an 8-year-old young girl. We discuss clinical, pathological, radiological findings and management of temporal bone RMS. Misdiagnosis is common because of this aggressive temporal bone lesion's similarity to more common benign diseases. Clinicians should maintain suspicion for RMS in patients with chronic otitis media not responsive to medical therapy and should refer a specialist multidisciplinary team in a timely manner as an early diagnosis will optimize the chance of survival. Clinical features, radiologic findings, and histopathological examination using immunohistochemistry are all important for the correct diagnosis of temporal bone RMS. It is important to be aware of and to know how to deal with such rare cases.
横纹肌肉瘤(RMS)是儿童时期最常见的软组织肉瘤之一。最常见的部位是头部和颈部,其次是泌尿生殖系统、四肢和躯干。头颈部是一个常见的部位,尽管颞骨是一个极其罕见的部位,迄今为止文献中只有少数病例报道。在此,我们报告一例8岁年轻女孩的硬化型颞骨RMS。我们讨论颞骨RMS的临床、病理、放射学表现和处理。误诊是常见的,因为这种侵袭性颞骨病变与更常见的良性疾病相似。对于对药物治疗没有反应的慢性中耳炎患者,临床医生应保持对RMS的怀疑,并应及时转诊多学科专家团队,因为早期诊断将优化生存机会。临床特征、放射学表现和使用免疫组织化学的组织病理学检查对于颞骨RMS的正确诊断都很重要。意识到并知道如何处理这种罕见的病例是很重要的。
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引用次数: 0
Persistent postural-perceptual dizziness: A multispecialty survey of clinician awareness and practices in Malaysia 持续性体位性知觉头晕:马来西亚临床医生意识和实践的多专业调查
IF 0.1 Q4 OTORHINOLARYNGOLOGY Pub Date : 2022-01-01 DOI: 10.4103/indianjotol.indianjotol_149_21
C. Teh, Salim Iffah, N. Prepageran
Objectives: Persistent postural-perceptual dizziness (PPPD) is a chronic functional vestibular disorder which is also the most common cause of chronic dizziness. Effective treatment is dependent on the awareness of the provider's knowledge of PPPD and correct provision of treatment. This study was aimed to assess the awareness of PPPD and practice patterns among a diverse group of providers who care for patients with chronic dizziness in the outpatient clinics. Materials and Methods: A 12-question web-based survey was distributed to a cross-sectional convenience sample of medical providers from primary care including general practitioners, otorhinolaryngology (ORL) and internal medicine all over Malaysia. We analyzed the responses using multivariate logistic regression. Results: Of the 186 included responses, only 46.7% (85 respondents) replied they have heard of PPPD and 158 (84.9%) have actually encountered patients with symptoms describing PPPD. Those in primary care had less odds of having heard of PPPD (adjusted odds ratio [aOR] 0.37 confidence interval [CI] 0.18–0.76) nor treated patients with PPPD symptoms (aOR 0.18 CI 0.07–0.49) when compared to the General Medical and ORL providers. In terms of treatment of PPPD, gender, level of training, and practice setting predicted the provision of therapy. Conclusion: PPPD awareness is still lacking among our providers and the current practices reflect that the management of chronic dizziness is focused on ruling out systemic causes. Now is the time to invest in health communication strategies to improve the awareness and knowledge of managing chronic dizziness especially PPPD.
目的:持续性体位性知觉性眩晕(PPPD)是一种慢性功能性前庭障碍,也是引起慢性眩晕的最常见原因。有效的治疗取决于提供者对PPPD知识的认识和正确的治疗。本研究旨在评估门诊护理慢性头晕患者的不同提供者对PPPD的认识和实践模式。材料和方法:将一项12个问题的网络调查分发给来自马来西亚各地初级保健医疗提供者的横断面便利样本,包括全科医生、耳鼻喉科医生和内科医生。我们使用多元逻辑回归分析了反应。结果:在186份回复中,只有46.7%(85名受访者)回答他们听说过PPPD,158名(84.9%)实际遇到过有PPPD症状的患者。与普通医疗和ORL提供者相比,初级保健提供者听说过PPPD的几率较小(调整后的比值比[aOR]0.37置信区间[CI]0.18-0.76),也没有治疗过PPPD症状的患者(aOR 0.18 CI 0.07-0.49)。在PPPD的治疗方面,性别、训练水平和实践环境预测了治疗的提供。结论:我们的提供者仍然缺乏PPPD意识,目前的做法反映出慢性头晕的管理侧重于排除系统性原因。现在是时候投资于健康沟通策略,以提高管理慢性头晕(尤其是PPPD)的意识和知识了。
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引用次数: 1
Speech recognition, quality of hearing, and data logging statistics over time in adult cochlear implant users 成人人工耳蜗使用者的语音识别、听力质量和随时间的数据记录统计
IF 0.1 Q4 OTORHINOLARYNGOLOGY Pub Date : 2022-01-01 DOI: 10.4103/indianjotol.indianjotol_51_22
G. Malzanni, Caterina Lerda, R. Battista, Chiara Canova, O. Gatti, M. Bussi, L. Piccioni
Objective: The objective of this study was to examine improvement in speech recognition and “the Speech, Spatial and Qualities of Hearing Scale” (SSQ) scores in monolateral cochlear implant (CI) users and its correlations to data logging statistics. Materials and Methods: A prospective observational, nonrandomized, study was conducted analyzing speech tracking with shielded mouth in noise (SMn), speech audiometry, and SSQ questionnaire (Italian version) at 1, 3, and 6 months postactivation of CI of 31 patients. The overall data of average daily use and acoustic scene analyses were extracted from data logging system. Data of 6-month cumulative speech in quiet-, speech-in-noise-, and noise-listening time of 19 patients were correlated to speech perception scores and SSQ scores. Results: An improvement was observed in all outcomes (speech tracking with SMn, speech audiometry, and SSQ scores). Listeners used their device on for a mean time of 13.45 h per day. Quiet scene was the most represented listening environment. A significant positive correlation was found between noise exposition (in hours) and hearing quality score of SSQ and between exposition to 60–69 dB noise and scores resulted from each part of SSQ. Discussion: The analysis failed to demonstrate a correlation between auditory performances and both exposition to speech scene and total exposition. However, time spent in noise using the device correlated with SSQ scores. Conclusion: Cochlear implantation ensures good results in speech recognition and quality of life, with progressive scores' improvement after activation. A predominant use in quiet was observed together with a correlation between hearing performance and exposition to noise.
目的:本研究的目的是检验单侧人工耳蜗(CI)用户在语音识别和“语音、空间和听力质量量表”(SSQ)评分方面的改善及其与数据记录统计的相关性。材料和方法:进行了一项前瞻性观察性非随机研究,分析了31名患者在CI激活后1、3和6个月使用屏蔽口噪声(SMn)进行的言语跟踪、言语测听和SSQ问卷(意大利版)。从数据记录系统中提取了平均日使用和声场景分析的总体数据。19名患者的6个月累计安静语音、噪声语音和噪声听音时间数据与语音感知得分和SSQ得分相关。结果:观察到所有结果(SMn语音跟踪、语音测听和SSQ评分)均有改善。听众平均每天使用设备13.45小时。安静的场景是最具代表性的聆听环境。噪声暴露(以小时为单位)与SSQ的听力质量分数之间存在显著的正相关,暴露于60–69 dB噪声与SSQ各部分的分数之间存在明显的正相关。讨论:该分析未能证明听觉表现与对演讲场景的阐述和全面阐述之间的相关性。然而,使用该设备在噪声中花费的时间与SSQ分数相关。结论:人工耳蜗植入能保证良好的语音识别效果和生活质量,激活后评分逐步提高。观察到安静的主要用途以及听力表现和暴露于噪音之间的相关性。
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引用次数: 1
Minimum access mastoidectomy 最小通道乳突切除术
IF 0.1 Q4 OTORHINOLARYNGOLOGY Pub Date : 2022-01-01 DOI: 10.4103/indianjotol.indianjotol_171_21
M. Taneja
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引用次数: 0
High-dose-rate brachytherapy boost following external radiotherapy in a case of carcinoma external ear 外耳癌放疗后高剂量率近距离放疗1例
IF 0.1 Q4 OTORHINOLARYNGOLOGY Pub Date : 2022-01-01 DOI: 10.4103/indianjotol.indianjotol_104_21
Jayesh Singh, Aastha Shah, Ankita Parikh, Isha Shah, D. Anand, Himanshi Jain, U. Suryanarayan
Squamous cell carcinoma of the external ear is rare and the combination of external beam radiotherapy and brachytherapy has been beneficial for tumors in this location due to the advantage of organ preservation and thereby cosmesis. The incorporation of brachytherapy allows the delivery of doses large enough for the eradication of tumor and the advantage of rapid dose fall off due to brachytherapy minimizes the radiation damage to the nearby organs at risk. Herein we report a case of elderly male with early stage squamous cell carcinoma of external ear treated with a combination of external beam radiation with brachytherapy. An eighty nine year old male reported to our hospital with the complaints of left sided ear ache the presence of some mass in the left external ear. A diagnostic Contrast enhanced Computed Tomography (CECT) scan of head and neck showed a 1.6*1.5*1.4 cm mass lesion (maximum diameter) involving anterior cartilaginous part of left external auditory canal and preauricular soft tissue,thereby staged as T2N0,stage II. Patient was planned for External Beam Radiotherapy (EBRT) using 3D CRT(Conformal Radiotherapy) technique by 6 MV photon beam to a dose of 50 Gy in 25 fractions (2 Gy/#) and following this,a gap of seven days was given and after that four fractions of HDR brachytherapy using Iridium 192 of 3 Gy/# keeping a gap of six hours between two fractions on a single day,Two flexible plastic tubes were used for radiation delivery. The size of the catheter used for radiation delivery was 6 French. Planning CT scan was taken and target volume defined as PTV and a dose of 3 Gy per fraction to a total of 4 fractions was prescribed to the target volume. The spike of intravenous site was used for fixing the plastic tube in the mould. The tumor responded ver well to radiotherapy. Brachytherapy is an effective modality to boost high risk areas without significant damage to the surrounding area. External Beam Radiotherapy in case of early stage carcinoma external auditory canal combined with brachytherapy boost can be considered as a better modality with less severe side effects and better cosmesis.
外耳鳞状细胞癌是罕见的,由于器官保存和美容的优势,外束放疗和近距离放疗的结合对该部位的肿瘤是有益的。近距离放射治疗的结合允许提供足够大的剂量来根除肿瘤,并且由于近距离放射治疗的快速剂量下降的优势最大限度地减少了对附近危险器官的辐射损伤。在此,我们报告一例老年男性早期外耳鳞状细胞癌的治疗与外束放射联合近距离治疗。一名89岁男性患者以左外耳肿物伴左耳疼痛来我院就诊。头颈部ct (CECT)诊断示1.6*1.5*1.4 cm肿块(最大直径),累及左侧外耳道前软骨部及耳前软组织,分期为T2N0, II期。患者计划使用3D CRT(适形放疗)技术进行外束放疗(EBRT),使用6 MV光子束,剂量为50 Gy,分为25份(2 Gy/#),之后给予7天的间隔,之后使用3gy /#的铱192进行4份HDR近距离放疗,在一天内两份之间保持6小时的间隔,使用两个柔性塑料管进行辐射输送。用于放射输送的导管尺寸为6法国。计划进行CT扫描,将靶体积定义为PTV,并对靶体积规定每分数3 Gy的剂量,共4个分数。静脉注射部位的尖头用于将塑料管固定在模具中。肿瘤对放射治疗反应很好。近距离放射治疗是一种有效的方式,可以促进高风险区域,而不会对周围区域造成重大损害。外耳道外束放疗联合近距离强化治疗是一种副作用小、美容效果好的治疗方法。
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引用次数: 0
Cortical emissary vein: An important vessel to look for before bone anchored hearing aid implantation 皮质发射静脉:骨锚定助听器植入前需要寻找的重要血管
IF 0.1 Q4 OTORHINOLARYNGOLOGY Pub Date : 2022-01-01 DOI: 10.4103/indianjotol.indianjotol_146_21
A. Dahlan, I. Zainon, Z. Yeoh, Mohd Khairi Md Daud
Bone anchored hearing aid (BAHA) is a device that combines a sound processor with a small titanium fixture implanted at the mastoid area. It is indicated for those having conductive hearing loss, especially in those not suitable for hearing aids. Emissary veins are residual connections between intracerebral veins and their extracranial drainage. The vein may be injured at the time of drilling procedure such as during insertion of implant at the mastoid area. We report a case of difficult BAHA surgery after encounter with cortical emissary vein. Mastoid emissary vein is a rare but definite entity which if not diagnosed preoperatively could be a cause of severe hemorrhage intraoperatively.
骨锚助听器(BAHA)是一种将声音处理器与植入乳突区域的小型钛固定装置相结合的设备。它适用于那些有传导性听力损失的人,尤其是那些不适合使用助听器的人。使静脉是脑内静脉与其颅外引流之间的残余连接。静脉可能在钻孔过程中受伤,例如在乳突区域插入植入物期间。我们报告了一例在遇到皮质发射静脉后难以进行BAHA手术的病例。Mastoid发射静脉是一种罕见但明确的实体,如果术前未诊断,可能是术中严重出血的原因。
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引用次数: 0
期刊
Indian Journal of Otology
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