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Antimicrobial Resistance in Enterococcus faecalis and Enterococcus faecium Bacteria Isolated from Bloodstream Infections: A Single-Center Evaluation 从血液感染中分离的粪肠球菌和粪肠球菌的抗菌素耐药性:一项单中心评估
IF 0.3 Q4 Medicine Pub Date : 2021-01-01 DOI: 10.36519/KD.2021.07
C. Çelik, Ayşe Hümeyra Taşkın-Kafa, M. Hasbek, Seyit Ali Büyüktuna
Objective: Enterococci are an important cause of healthcare-related bloodstream infections. The present study aimed to contribute to form empirical treatment models that can be used in the treatment of Enterococcus faecalis and Enterococcus faecium bacteria isolated from bloodstream infections in our hospital by reviewing their resistance status against antibiotics, requently used in the treatment of these bacteria. Methods: In our study, the resistance status of E. faecalis and E. faecium bacteria isolated from bloodstream infections in Sivas Cumhuriyet University, Health Services Practice and Research Hospital between January 2015 and June 2020 against ampicillin, amoxicillin, clavulanic acid, high-level gentamicin, linezolid, teicoplanin, and vancomycin was examined retrospectively. The diagnosis of healthcare-related bloodstream infections was made using the diagnostic criteria of “Centers for Diseases Control and Prevention (CDC).” Results: A total of 227 enterococcal isolates were evaluated within the scope of our study between the specified dates. The percentage of patients with Enterococcus bacteria isolated in their blood cultures were 44.5% male, and 55.5% female. Of the isolates, 60.8% were identified as E. faecalis and 39.2%as E. faecium. High-level gentamicin resistance was found to be 25.3% in E. faecalis isolates, and no resistance was found against vancomycin, teicoplanin, and linezolid. In E. faecium isolates, while the highest resistance was observed against amoxicillin-clavulanic acid and ampicillin with 87.6%, vancomycin resistance was determined to be 3.3%. No resistance to linezolid was identified. Conclusions: Enterococci cause life-threatening infections and there are some difficulties in the treatment. Especially since E. faecium has higher resistance against antibiotics, the agents to be chosen in the treatment of infections caused by these bacteria are limited. Therefore, the current local resistance data will be useful in developing rapid and appropriate treatment models, especially in cases when empirical treatment is required. We think that our study will contribute to the literature in this regard.
目的:肠球菌是卫生保健相关血流感染的重要原因。本研究旨在通过对我院血流感染中分离的粪肠球菌和粪肠球菌对常用抗生素的耐药情况进行综述,形成可用于治疗粪肠球菌和粪肠球菌的经验性治疗模型。方法:回顾性分析2015年1月至2020年6月在西瓦斯大学、卫生服务实践与研究医院血液感染中分离的粪肠杆菌和粪肠杆菌对氨苄西林、阿莫西林、克拉维酸、高水平庆大霉素、利奈唑胺、替柯planin和万古霉素的耐药情况。医疗相关血流感染的诊断采用“疾病控制与预防中心(CDC)”的诊断标准。结果:在我们的研究范围内,在指定日期之间共评估了227株肠球菌分离物。血培养分离出肠球菌的患者中,男性占44.5%,女性占55.5%。检出60.8%为粪肠杆菌,39.2%为粪肠杆菌。分离株庆大霉素耐药率为25.3%,对万古霉素、替柯planin和利奈唑胺无耐药。大肠杆菌对阿莫西林-克拉维酸和氨苄西林的耐药率最高,为87.6%,对万古霉素的耐药率为3.3%。未发现对利奈唑胺耐药。结论:肠球菌感染危及生命,治疗困难。特别是由于粪肠杆菌对抗生素具有较高的耐药性,因此在治疗这些细菌引起的感染时所选择的药物是有限的。因此,目前的当地耐药性数据将有助于制定快速和适当的治疗模式,特别是在需要经验性治疗的情况下。我们认为我们的研究将对这方面的文献有所贡献。
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引用次数: 2
Evaluation of Health Care Workers With COVID-19 对感染COVID-19的医护人员的评估
IF 0.3 Q4 Medicine Pub Date : 2020-12-31 DOI: 10.5152/kd.2020.48
E. Eren, I. Çelik, Merve Yıldız, U. Topaloğlu, Aysin Kilinc Toker, Emine Fırat, Abdullah Gur, Elif Bolat, A. Kılıc
Objective: In this study, we aimed to determine the contact risk levels of infected health care workers for patients with COVID- 19 and to evaluate their disease status Methods: Health care workers with COVID-19 were analyzed, retrospectively Close contact with patients was classified as high, medium, low-risk or risk-free contact according to the use of personal protective equipment, and transmission levels were evaluated Symptoms and disease severity after infection were determined Results: A total of 82 health care workers were infected during the study period, and only 2% had high-risk contact status There was risk-free contact in 71% of the patients Community/ family-borne contaminations were detected as the main source of transmission 82% of the infected health care workers have developed at least one symptom Fever (65%) and dry cough 54%) were more common symptoms According to their clinical severity, 66% of them had mild illness Only one had severe illness All the health care workers with COVID-19 recovered and were discharged Conclusions: Health care workers are at increased risk of COVID- 19 transmission In addition to the use of appropriate personal protective equipment, masks and social distance rules should be followed in social settings (English) [ABSTRACT FROM AUTHOR] Amaç: Bu çalışmada COVID-19 hastalarına bakan infekte sağlık çalışanlarının temas risk durumlarının belirlenmesi ve hastalık durumlarının değerlendirilmesi amaçlanmıştır Yöntemler: COVID-19 geçiren sağlık çalışanları retrospektif olarak değerlendirilmiştir Hastalarla olan yakın temasları, kişisel koruyucu ekipman kullanımlarına göre yüksek, orta, düşük riskli veya risksiz temas olarak sınıflandırılmış ve bulaşma düzeyleri değerlendirilmiştir Ínfekte olduktan sonra gelişen semptomlar ve hastalığın ağırlığı belirlenmiştir Bulgular: Çalışma süresi boyunca toplam 82 sağlık çalışanı infekte olmuştur ve sadece %2'sinde yüksek riskli temas vardı Risksiz temas ise %71'inde saptanmıştır Başlıca bulaşma kaynağı olarak ise toplum/aile kaynaklı bulaşma saptanmıştır Ínfekte sağlık çalışanlarının %82'sinde en az bir semptom gelişmiştir Ateş (%65) ve kuru öksürük (%54) en sık görülen semptomlardı Klinik ağırlıklarına göre %66'sı, hastalığı hafif şekilde atlatmıştı Yalnızca bir sağlık çalışanı ağır hastalık tablosu gösterdi COVID-19 saptanan sağlık çalışanlarının tamamı iyileşerek taburcu edilmiştir Sonuçlar: Sağlık çalışanlarına COVID-19 bulaşması riski artmıştır Uygun kişisel koruyucu ekipman kullanımının yanında, sosyal ortamlarda da maske ve sosyal mesafe kurallarına uyulmalıdır (Turkish) [ABSTRACT FROM AUTHOR] Copyright of Klimik Journal / Klimik Dergisi is the property of Turkish Society of Clinical Microbiology & Infectious Diseases and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission However, users may print, download, or email articles for individual use This abstract ma
目的:本研究旨在确定感染COVID-19的医护人员的接触风险水平,并评估其疾病状况。方法:对感染COVID-19的医护人员进行回顾性分析,根据个人防护装备的使用情况将与患者密切接触者分为高、中、低风险或无风险接触者,并评估传播水平。在研究期间,共有82名卫生保健工作者被感染,只有2%为高危接触者,71%的患者无风险接触,社区/家庭传播的污染被检测为主要传播源,82%的受感染卫生保健工作者出现至少一种症状,根据其临床严重程度,发烧(65%)和干咳(54%)是更常见的症状。所有感染COVID-19的医务人员均已康复出院。结论:医务人员传播COVID-19的风险增加,除使用适当的个人防护装备外,在社交场合应遵守佩戴口罩和保持社交距离的规则(英文)[摘要/作者]Amaç:但是çalışmada COVID-19 hastalarına bakan infection sağlık çalışanlarının temas risk durumlarının belirlenmesi ve hastalık durumlarının değerlendirilmesi amaçlanmıştır Yöntemler:2019 -19 ge:马卡尔ışsuresi boyunca toplam 82 sağl kı卡尔ış一个ıinfekte olmuş病重ve sadece % 2 'sinde yuksek riskli特马vardıRisksiz特马伊势% 71 'inde saptanmışt r英航şılıca布拉ş马kaynağıolarak伊势toplum /爱乐kaynaklı布拉ş马saptanmıştır Í nfekte sağl kı卡尔ışanlarının % 82 'sinde en az bir semptom gelişmiş行动感到吃ş(% 65)ve库鲁病oksuruk(% 54)在年代kıgorulen semptomlardıKlinik一ğırlıklarına戈尔% 66的ı,hastalığı hafiif ekilde atlatmıştı Yalnızca bir sağlık çalışanı ağır hastalık tablosu gösterdi COVID-19 saptanan sağlık çalışanlarının tamamiliyile erek taburcu edilmiurer sonular:Sağlık çalışanlarına 2019 -19 bulla masyi riski artmıştır Uygun ki isel koruyucu ekipman kullanımının yanında, sosyal ortamlarda da maske ve sosyal mesafe kurallarına uyulmalıdır(土耳其)[摘要]Klimik Journal / Klimik Dergisi版权归土耳其临床微生物学与传染病学会所有,未经版权所有者明确书面许可,不得将其内容复制或通过电子邮件发送到多个网站或发布到listserv。用户可以打印、下载或通过电子邮件发送文章供个人使用,本摘要可能会被删节,但不保证副本的准确性,用户应参考原始发布的完整摘要(版权适用于所有摘要)。
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引用次数: 6
Retrospective Evaluation of Positive Blood Culture of Bacteremic Cases With Fatal Outcome 血培养阳性致死性菌血症病例的回顾性评价
IF 0.3 Q4 Medicine Pub Date : 2020-12-31 DOI: 10.5152/kd.2020.57
Gamze Kalin Unuvar, F. Cetinkaya, Zeynep Ture Yuce, A. Kılıc
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引用次数: 0
Comorbidities, Antiretroviral Therapy Switches, and Drug Side-Effects Among HIV-Infected Patients hiv感染患者的合并症、抗逆转录病毒治疗切换和药物副作用
IF 0.3 Q4 Medicine Pub Date : 2020-12-31 DOI: 10.5152/kd.2020.50
O. Evlice, S. Başaran, S. Yavuz, A. Çağatay, O. Oncul, H. Ozsut, H. Eraksoy
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引用次数: 0
Fosfomycin: Flashback 磷霉素:闪回
IF 0.3 Q4 Medicine Pub Date : 2020-12-31 DOI: 10.5152/kd.2020.46
Gulsen Hazirolan
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引用次数: 0
Cytomegalovirus Colitis in a Patient With Ulcerative Colitis 溃疡性结肠炎患者巨细胞病毒结肠炎1例
IF 0.3 Q4 Medicine Pub Date : 2020-12-31 DOI: 10.5152/kd.2020.64
O. Akdogan, D. Yapar, T. Duzenli, Gulcan Kaplan, Pinar Tuncel Ozturk, Tugba Ozcerezci, A. Çelikbaş, N. Baykam
Cytomegalovirus (CMV) can cause severe, persistent
巨细胞病毒(CMV)可引起严重的、持续性的
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引用次数: 1
Two Cases of Orf Complicated With Erythema Multiforme 溃疡并发多形性红斑2例
IF 0.3 Q4 Medicine Pub Date : 2020-12-31 DOI: 10.5152/kd.2020.63
Mehmet Yildirim, O. Karaşahin
Orf, özellikle koyun ve keçilerle ilgilenen çiftçilerde görülen, yüksek düzeyde bulaşıcı ve kendini sınırlayan bir infeksiyon hastalığıdır. Etken, Poxviridae ailesinin Parapoxvirus cinsinden çift iplikli bir DNA virusu olan orf virusudur. Orf, sekonder bakteriyel infeksiyon, lenfadenopati, lenfanjit ve erythema multiforme ile komplike olabilir. Bu yazıda koyun teması sonrası gelişen ve erythema multiforme ile komplike olan iki orf olgusu sunulacaktır. Klimik Dergisi 2020; 33(3): 317-9. Anahtar Sözcükler: Erythema multiforme, orf. Abstract
Orf是一种高度传染性和自我限制性感染,在关注绵羊和山羊的农民中传播。这是一种orfa病毒,带有来自副痘病毒家族的双液DNA病毒。Orf、继发性细菌感染、lenfadenopath、lenphagia和多形性红斑可能是相容的。在这篇文章中,将在羊的主题之后呈现两个与多种形式兼容的孤儿。《2020年气候报告》;33(3):317-9。关键词:多形性红斑,orf。摘要
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引用次数: 0
A Clinical and Laboratory-Defined Case of COVID-19 Reinfection 1例临床和实验室诊断的COVID-19再感染病例
IF 0.3 Q4 Medicine Pub Date : 2020-12-31 DOI: 10.5152/kd.2020.62
Ismail Turkoz, Mehmet Ali Tuz, E. Gençer, Fadime Ozge Aygun Kas, T. Yıldırmak, Gogus Hastaliklari Klinigi Zonguldak Turkiye Zonguldak Ataturk Devlet Hastanesi
While the COVID-19 pandemic which emerged in China at the end of 2019 and affected the whole world continues its effect all over the world;there are still questions in our minds regarding reinfection and prolonged infection We report a case of COVID- 19 reinfection detected in a patient presenting with similar symptoms approximately 5 months after the first infection (English) [ABSTRACT FROM AUTHOR] 2019 yılının sonunda Çin'de ortaya çıkan ve tüm dünyayı etkisi altına alan COVID-19 pandemisi tüm dünyada etkisini sürdürürken reinfeksiyon ve uzamış infeksiyonla ilgili soru işaretleri devam etmektedir Bu bildiride ilk infeksiyondan yaklaşık 5 ay sonra benzer semptomlarla başvuran bir hastada saptanmış bir COVID-19 reinfeksiyonu olgusu sunulmuştur (Turkish) [ABSTRACT FROM AUTHOR] Copyright of Klimik Journal / Klimik Dergisi is the property of Turkish Society of Clinical Microbiology & Infectious Diseases and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission However, users may print, download, or email articles for individual use This abstract may be abridged No warranty is given about the accuracy of the copy Users should refer to the original published version of the material for the full abstract (Copyright applies to all Abstracts )
随着2019年底在中国出现并影响到全世界的新冠肺炎疫情继续在世界各地产生影响;关于再次感染和长期感染,我们仍有疑问我们报告了一例新冠肺炎-19再次感染病例,该患者在首次感染后约5个月出现类似症状(英文)[摘要来自作者]2019年sürdürürken reineksiyon ve uzamı未经版权持有人明确书面许可,不得将疾病及其内容复制或通过电子邮件发送到多个网站或发布到listserv。然而,用户可以打印、下载、,或个人使用的电子邮件文章本摘要可能会被删节,对副本的准确性不作任何保证用户应参考材料的原始出版版本以获取完整摘要(版权适用于所有摘要)
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引用次数: 0
Evaluation of Syphilis Coinfection in HIV-Infected Individuals hiv感染者梅毒合并感染的评价
IF 0.3 Q4 Medicine Pub Date : 2020-12-31 DOI: 10.5152/kd.2020.59
H. Dinc, Sena Alkan, Doğukan Özbey, S. Sirekbasan, N. Gareayaghi, Merve Cihan, S. Akkus, B. Mete, F. Tabak, H. B. Tokman, B. Kocazeybek
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引用次数: 0
Current Status in Intestinal Parasitic Infections: A Reference Laboratory Results 肠道寄生虫感染的现状:参考实验室结果
IF 0.3 Q4 Medicine Pub Date : 2020-12-31 DOI: 10.5152/kd.2020.61
S. Usluca, C. Babür, S. Kılıç
Yazışma Adresi / Address for Correspondence: Selma Usluca, Sağlık Bakanlığı, Halk Sağlığı Genel Müdürlüğü, Mikrobiyoloji Referans Laboratuvarları ve Biyolojik Ürünler Daire Başkanlığı, Sıhhiye, Ankara, Türkiye E-posta / E-mail: selmausluca@gmail.com (Geliş / Received: 28 Kasım / November 2019; Kabul / Accepted: 30 Kasım / November 2020) DOI: 10.5152/kd.2020.61 Barsak Paraziti İnfeksiyonlarında Son Durum: Bir Referans Laboratuvarı Sonuçları
通讯地址:Selma Usluca,卫生部公共卫生经理,微生物参考实验室和生物制品局,瑞典,土耳其安卡拉,电子邮件:selmausluca@gmail.com(高级/接收日期:2019年11月28日;接受日期:2020年11月30日)
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引用次数: 0
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Klimik Journal
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